LOCUS       DAPBBR010000001        94641 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPBBR010000001 DAPBBR010000000
VERSION     DAPBBR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 94641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.001"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(99..1229)
                     /locus_tag="RD488_000001"
     CDS             complement(99..1229)
                     /locus_tag="RD488_000001"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDT7656109.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDRLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="RD488_000002"
     CDS             complement(1878..3080)
                     /locus_tag="RD488_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7656110.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQKYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="RD488_000003"
     CDS             complement(3140..3343)
                     /locus_tag="RD488_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HDT7656111.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="RD488_000004"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="RD488_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="RD488_000005"
     CDS             4880..5692
                     /locus_tag="RD488_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656112.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6913)
                     /locus_tag="RD488_000006"
     CDS             complement(6716..6913)
                     /locus_tag="RD488_000006"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7656113.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="RD488_000007"
     CDS             complement(7059..7937)
                     /locus_tag="RD488_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7656114.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="RD488_000008"
     CDS             complement(7976..9094)
                     /locus_tag="RD488_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HDT7656115.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="RD488_000009"
     CDS             complement(9091..11190)
                     /locus_tag="RD488_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HDT7656116.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="RD488_000010"
     CDS             complement(11241..12062)
                     /locus_tag="RD488_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7656117.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="RD488_000011"
     CDS             complement(12059..12868)
                     /locus_tag="RD488_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7656118.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="RD488_000012"
     CDS             complement(12889..13383)
                     /locus_tag="RD488_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7656119.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="RD488_000013"
     CDS             complement(13395..13883)
                     /locus_tag="RD488_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7656120.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="RD488_000014"
     CDS             complement(13960..16656)
                     /locus_tag="RD488_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7656121.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="RD488_000015"
     CDS             complement(17084..18157)
                     /locus_tag="RD488_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7656122.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="RD488_000016"
     CDS             complement(18154..18981)
                     /locus_tag="RD488_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656123.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="RD488_000017"
     CDS             complement(18982..19788)
                     /locus_tag="RD488_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656124.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="RD488_000018"
     CDS             complement(19800..20885)
                     /locus_tag="RD488_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656125.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="RD488_000019"
     CDS             complement(20902..21444)
                     /locus_tag="RD488_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7656126.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="RD488_000020"
     CDS             21702..22691
                     /locus_tag="RD488_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDT7656127.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="RD488_000021"
     CDS             22688..23425
                     /locus_tag="RD488_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HDT7656128.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="RD488_000022"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="RD488_000022"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HDT7656129.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="RD488_000023"
     CDS             23989..24621
                     /locus_tag="RD488_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7656130.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="RD488_000024"
     CDS             24706..25353
                     /locus_tag="RD488_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7656131.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="RD488_000025"
     CDS             25358..26341
                     /locus_tag="RD488_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HDT7656132.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="RD488_000026"
     CDS             complement(26744..28258)
                     /locus_tag="RD488_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HDT7656133.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="RD488_000027"
     CDS             28396..29202
                     /locus_tag="RD488_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656134.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="RD488_000028"
     CDS             complement(29377..29946)
                     /locus_tag="RD488_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7656135.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30074..32089)
                     /locus_tag="RD488_000029"
     CDS             complement(30074..32089)
                     /locus_tag="RD488_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HDT7656136.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGT"
     gene            complement(32366..33844)
                     /locus_tag="RD488_000030"
     CDS             complement(32366..33844)
                     /locus_tag="RD488_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656137.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="RD488_000031"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="RD488_000031"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDT7656138.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="RD488_000032"
     CDS             complement(35150..36070)
                     /locus_tag="RD488_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7656139.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="RD488_000033"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="RD488_000033"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDT7656140.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="RD488_000034"
     CDS             37799..38332
                     /locus_tag="RD488_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HDT7656141.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38822..39346)
                     /locus_tag="RD488_000035"
     CDS             complement(38822..39346)
                     /locus_tag="RD488_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7656142.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="RD488_000036"
     CDS             complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="RD488_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDT7656143.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39935..40915)
                     /gene="pta"
                     /locus_tag="RD488_000037"
     CDS             complement(39935..40915)
                     /gene="pta"
                     /locus_tag="RD488_000037"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDT7656144.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41068..41748)
                     /locus_tag="RD488_000038"
     CDS             complement(41068..41748)
                     /locus_tag="RD488_000038"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7656145.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41874..42743
                     /locus_tag="RD488_000039"
     CDS             41874..42743
                     /locus_tag="RD488_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7656146.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42769..43284
                     /locus_tag="RD488_000040"
     CDS             42769..43284
                     /locus_tag="RD488_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656147.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43331..43924)
                     /locus_tag="RD488_000041"
     CDS             complement(43331..43924)
                     /locus_tag="RD488_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7656148.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43949..44128)
                     /locus_tag="RD488_000042"
     CDS             complement(43949..44128)
                     /locus_tag="RD488_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656149.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44205..44714)
                     /locus_tag="RD488_000043"
     CDS             complement(44205..44714)
                     /locus_tag="RD488_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656150.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44810..45190)
                     /locus_tag="RD488_000044"
     CDS             complement(44810..45190)
                     /locus_tag="RD488_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7656151.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45520..46269
                     /locus_tag="RD488_000045"
     CDS             45520..46269
                     /locus_tag="RD488_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HDT7656152.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46453..47730)
                     /locus_tag="RD488_000046"
     CDS             complement(46453..47730)
                     /locus_tag="RD488_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656153.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="RD488_000047"
     CDS             complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="RD488_000047"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDT7656154.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48652..49596)
                     /locus_tag="RD488_000048"
     CDS             complement(48652..49596)
                     /locus_tag="RD488_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDT7656155.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49598..50284)
                     /locus_tag="RD488_000049"
     CDS             complement(49598..50284)
                     /locus_tag="RD488_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDT7656156.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50758..51078
                     /locus_tag="RD488_000050"
     CDS             50758..51078
                     /locus_tag="RD488_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HDT7656157.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51232..52137
                     /locus_tag="RD488_000051"
     CDS             51232..52137
                     /locus_tag="RD488_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656158.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52134..52907
                     /locus_tag="RD488_000052"
     CDS             52134..52907
                     /locus_tag="RD488_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7656159.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53088..54512)
                     /locus_tag="RD488_000053"
     CDS             complement(53088..54512)
                     /locus_tag="RD488_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7656160.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54723..55169
                     /gene="nrdI"
                     /locus_tag="RD488_000054"
     CDS             54723..55169
                     /gene="nrdI"
                     /locus_tag="RD488_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDT7656161.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55234..57216)
                     /locus_tag="RD488_000055"
     CDS             complement(55234..57216)
                     /locus_tag="RD488_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7656162.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSAATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="RD488_000056"
     CDS             complement(57230..58126)
                     /gene="murQ"
                     /locus_tag="RD488_000056"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7656163.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58129..59190)
                     /locus_tag="RD488_000057"
     CDS             complement(58129..59190)
                     /locus_tag="RD488_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7656164.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59401..59967)
                     /locus_tag="RD488_000058"
     CDS             complement(59401..59967)
                     /locus_tag="RD488_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7656165.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="RD488_000059"
     CDS             complement(59995..61497)
                     /gene="eat(A)"
                     /locus_tag="RD488_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7656166.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKSQPKHLSISYVRQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61755..62876)
                     /locus_tag="RD488_000060"
     CDS             complement(61755..62876)
                     /locus_tag="RD488_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7656167.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPHGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63001..63942
                     /locus_tag="RD488_000061"
     CDS             63001..63942
                     /locus_tag="RD488_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7656168.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFRSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKTAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64092..64988)
                     /locus_tag="RD488_000062"
     CDS             complement(64092..64988)
                     /locus_tag="RD488_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7656169.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLAYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPIPSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65257..66597
                     /locus_tag="RD488_000063"
     CDS             65257..66597
                     /locus_tag="RD488_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7656170.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66815..67258
                     /locus_tag="RD488_000064"
     CDS             66815..67258
                     /locus_tag="RD488_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7656171.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(67523..68941)
                     /gene="nhaC"
                     /locus_tag="RD488_000065"
     CDS             complement(67523..68941)
                     /gene="nhaC"
                     /locus_tag="RD488_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7656172.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(69344..70567)
                     /locus_tag="RD488_000066"
     CDS             complement(69344..70567)
                     /locus_tag="RD488_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDT7656173.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVIAASIVEQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(70598..71437)
                     /locus_tag="RD488_000067"
     CDS             complement(70598..71437)
                     /locus_tag="RD488_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7656174.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETTVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDEKNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(71454..72134)
                     /locus_tag="RD488_000068"
     CDS             complement(71454..72134)
                     /locus_tag="RD488_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656175.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(72136..73209)
                     /locus_tag="RD488_000069"
     CDS             complement(72136..73209)
                     /locus_tag="RD488_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656176.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IIEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKINILQKNELDSRIKVIEGGR"
     misc_binding    complement(73265..73503)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(73545..73778)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(73855..74526)
                     /locus_tag="RD488_000070"
     CDS             complement(73855..74526)
                     /locus_tag="RD488_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7656177.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYFDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(74613..77291)
                     /gene="mgtA"
                     /locus_tag="RD488_000071"
     CDS             complement(74613..77291)
                     /gene="mgtA"
                     /locus_tag="RD488_000071"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDT7656178.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLTFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASMFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNVTFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIHRFQELL"
     gene            77950..78387
                     /gene="ndk"
                     /locus_tag="RD488_000072"
     CDS             77950..78387
                     /gene="ndk"
                     /locus_tag="RD488_000072"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDT7656179.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAVDAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(78409..79275)
                     /locus_tag="RD488_000073"
     CDS             complement(78409..79275)
                     /locus_tag="RD488_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7656180.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICSKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLSLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEKKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(79435..81528)
                     /locus_tag="RD488_000074"
     CDS             complement(79435..81528)
                     /locus_tag="RD488_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7656181.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWMKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVLYWLDIATFIGILVWLTIKKIPIKSQPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFSESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSAIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWNEFDN
                     AQMQRVPLMIHIPGYTKGSVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSPQHD
                     QVVAFRNGNFVTPKYTILGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKSALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNIAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKDNQ"
     gene            complement(82004..82627)
                     /locus_tag="RD488_000075"
     CDS             complement(82004..82627)
                     /locus_tag="RD488_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656182.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(82786..84183)
                     /locus_tag="RD488_000076"
     CDS             complement(82786..84183)
                     /locus_tag="RD488_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7656183.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHPEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(84215..85186)
                     /locus_tag="RD488_000077"
     CDS             complement(84215..85186)
                     /locus_tag="RD488_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7656184.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKELLEKGVTAIFVSNYNMSIGAIECFNQEGIRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGEQAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            85560..85985
                     /locus_tag="RD488_000078"
     CDS             85560..85985
                     /locus_tag="RD488_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656185.1"
                     /translation="MKKLIVLFILSAGLLTLTGCNLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQETDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATITFTKIGNYRLKDEDGNIYSL"
     gene            complement(86473..87174)
                     /locus_tag="RD488_000079"
     CDS             complement(86473..87174)
                     /locus_tag="RD488_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7656186.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIHQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(87190..87630)
                     /locus_tag="RD488_000080"
     CDS             complement(87190..87630)
                     /locus_tag="RD488_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7656187.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(87630..88205)
                     /locus_tag="RD488_000081"
     CDS             complement(87630..88205)
                     /locus_tag="RD488_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDT7656188.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(89052..89531)
                     /locus_tag="RD488_000082"
                     /pseudo
     CDS             complement(89052..89531)
                     /locus_tag="RD488_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(89690..90391)
                     /locus_tag="RD488_000083"
     CDS             complement(89690..90391)
                     /locus_tag="RD488_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7656189.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLHYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(90499..91908)
                     /locus_tag="RD488_000084"
     CDS             complement(90499..91908)
                     /locus_tag="RD488_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDT7656190.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(91956..93821)
                     /locus_tag="RD488_000085"
     CDS             complement(91956..93821)
                     /locus_tag="RD488_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7656191.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(93942..>94641)
                     /locus_tag="RD488_000086"
     CDS             complement(93942..>94641)
                     /locus_tag="RD488_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7656192.1"
                     /translation="DSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYL
                     TLTDHLHYAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEA
                     GFIAFHFVNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQF
                     FAQRYLKGEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTI
                     HIQRVVSEKKSIQS"
BASE COUNT        27708 a        19755 c        16280 g        30898 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ctatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atttttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacctatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38641 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38701 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38761 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38821 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    38881 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    38941 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39001 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39061 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39121 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39181 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39241 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39301 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39361 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39421 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39481 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39541 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39601 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39661 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39721 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39781 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39841 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    39901 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    39961 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40021 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40081 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40141 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40201 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40261 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40321 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40381 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40441 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40501 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40561 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40621 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40681 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40741 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40801 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40861 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    40921 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    40981 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41041 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41101 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41161 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41221 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41281 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41341 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41401 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41461 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41521 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41581 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41641 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41701 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41761 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41821 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    41881 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    41941 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42001 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42061 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42121 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42181 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42241 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42301 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42361 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42421 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42481 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42541 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42601 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42661 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42721 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42781 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42841 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    42901 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    42961 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43021 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43081 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43141 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43201 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43261 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43321 gtacatcttt ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct
    43381 gaccgacaac tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat
    43441 ccacacttag accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta
    43501 ataatcgcga accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat
    43561 accattcgtt gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat
    43621 atttctctaa gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac
    43681 cgtaagcaac tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt
    43741 aacgataatt tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg
    43801 tctgcttcaa aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt
    43861 ctggagcatc ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta
    43921 acatgcagaa aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa
    43981 tgaaataacc atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg
    44041 gcatttcttt atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc
    44101 cgcaattagg gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct
    44161 tagcttactc ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat
    44221 acctgacggt cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg
    44281 actagaagtg tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc
    44341 atcgctgctt gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg
    44401 gccttttccg tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact
    44461 tgtccttcac aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt
    44521 tcaactgcaa aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct
    44581 gctgcttttt tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg
    44641 gcattgagca gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac
    44701 atcatttttt tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa
    44761 cgaatgaaaa atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca
    44821 gttctaatgg caatccgtct ggatcaaaga aaaacgtcat tttttttcct gtaaaggtat
    44881 cttctctaat cggttctgat tcgatcccta aggactgcaa ttctgcaatt gtttcttcaa
    44941 tatcgtctac tttgaaagca agatgacgca agccacaagc ttctggatag tttggtcgtt
    45001 gtggcgcatt agcaattcca aaaatctcca attcagcact tcctagtttc agatctaatt
    45061 tatagtcatc tcgttctttg cggtaatttt ctctgattac ttcaaatcct aatttattaa
    45121 cataaaaatc acgtgatttc tgataatctg aaacaatgat ggctatatga tggatcgttg
    45181 taaggttcat atgagcactc ctattcttcg tttaagctcg gatctatatt aatctccagt
    45241 tccattgtaa atgtgtcaga ttgaaaaaaa tagctgtttt tcctttttat aagaaaaaag
    45301 gcaaaaaaaa cagaaagtag gtcctccaag acactcttcc tgttcccaat ataataaatg
    45361 aaagtaagaa attatatttt caagaaaaca aacagaaaat tatcataaca caaattattt
    45421 ataattgaaa gactagtttt ttttcaagaa aagcatacaa tagattgtgt tagtaaatac
    45481 agaacacact acatttagtg tcttaaggag tcctcataca tgaagtcata ttttcagttt
    45541 ttagctcatc agctaaaagg ctggccgcaa caaaattatt atcttttctt tttcagtctt
    45601 ggctgccagg tcatgactct tgtcaatagt cccatcactt ggctgtccgt tattacattt
    45661 atcggtacca cgcttggtgt attgtgtatt ttatccatca atgcggcaaa atcagtcaac
    45721 ggtattttag gtattttgtc tgcgatttgt tttattatcg ttgggttttc agcaaagaac
    45781 tatttaagta tcggtgaaca gattgcttat atgatcacat tggatatccc cgtattgtta
    45841 agtaaagaat ggaatcataa tatggcttca aaaatccgaa aattcactgg aaaaagctgg
    45901 tttatcgcaa tcatcagtac tttccttgtc tatcttgttt caggattcct gattggtcgt
    45961 tatacagatg atcctcggcc gtgggtagat gccattgctt tttctattag cttgactgct
    46021 ggtatcatca gtttcttgcg ttacaacaac caatattact ggtggttagc ttcagggctt
    46081 gctcaaatgg tcctttggta tatttcattt acgcatggat ctgcaagttt ggcgatgttc
    46141 gtgaacagct ctgtttactt gctgaatgat gtccttgcat ttaccgtttc accttggtat
    46201 aaccaaaaag aacgtgaacg tatgcaaaaa atggaagaag aatactacaa cgcacaacaa
    46261 cacgcataaa aaaactgagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    46321 acacgtataa acggcggaat cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    46381 atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc
    46441 agcctctatt ttttatagta attccttcag atactttctt gcctcatcat tgaaacgcag
    46501 tgattcttct aacttctgat aatattccaa cgcttgtttc tgagcttcag taaaacgata
    46561 atgttttcct ttccatttgt cgattgtctc ttgcacattt ccagattgga tatctttcac
    46621 tactagttgc catttttctt ttgagactgt acggtctttc ttatcagcag attgtatagc
    46681 ttctcgttct ttacgcaata cttttaaaaa accatttctg actatccgag gaatgctgtc
    46741 gaagaaccct tctgtaaaac catagcgaca atattgcttc caaataaata gatagatttt
    46801 tggttggatg aatcgttggt ttttcgcaaa atattccatc tgagcagtga cttctggtgt
    46861 tcgttgacgt tttgtctttc tcaacacgga aataaatgtt tcaaaataag cattaggatg
    46921 tactggcact tcttcatata cgatggattg ccaatcttta cgtaaaaatg cgcgatagtt
    46981 gatcaagaat tcttctacat cctttactaa ttcttctgca aagtcgtcaa atagttcttt
    47041 ttttatctgt cgcttttttg actgcccatt gatgtgttca cttattttct tgatttcatt
    47101 ttccaatgct tgataatccg ctatgtaaat cggcatttct acttggcgaa attctgcgag
    47161 ccgctgagct aattttatat ccggtaaata tggctgtttc atccgacgat tttggtacaa
    47221 gacaaaacag tatttttgcc atagtccttc aggaaaatcg atattcttct gcttaagcca
    47281 taataattcg tctaaggcca gatcaacttt tgtcattccc tgatggatcg aagctgccac
    47341 tgtcggagag acatgcaggt gatcggcaaa gtggttgatg cctagtttta ggatctttcc
    47401 ggtttttggc gatttaacga tgtattgcac ttttaattct ctaccacact cacaatacaa
    47461 tttttgctgg cttcgttttg ttcgaaaaaa cggattgatc ttgaagtcag aaaacaccca
    47521 atctgttgca gctaaataat gttcttccat aaaacgagag ctgattagat atcggcggtg
    47581 cttatcgact agttcccgct gttttttcgt taattttgca tagatctccc aacgttgact
    47641 gcttgtgtat tgtttagaaa ttttgatggg atagcttttg ctgatttctt ttggaaacca
    47701 ttcttcaaag acggattgcc attcttccac ggctgtttct ttcctttcta attacaaaaa
    47761 gctggctact aacataacgt tagcaaccag ccagtgtttc ttgctaaatt agtgagttgt
    47821 tccggcattt ccggaaatat cttctttatt ttctactgct gcttcaactg cataagtcaa
    47881 agaagaagca atgtcttcta aagacataga aggcgtaccc actggacgat cgatcacttg
    47941 atcgggtgag aatggcacgt ggatgaaccc acctcgaatt gccgggaatt gtgtttcgat
    48001 caaatgaagc aaacgataca tgatatcatt gcagacaaat gttcctgctg tataagagat
    48061 gtacgctggt agaccatgat cttgtacatt ttttgtcatt gctttgattg gcaatgaggt
    48121 aaagtaagcg gctggaccgt tttcttctaa agccgtatcg aatggctgat ttccttcatt
    48181 atcagggatt cttgcttctg ctagattgat tgcgacacgt tcgaacgaga ctgctgaccg
    48241 cccacctgct tgtccgacac agatcacgac atctggttgg tgctgttgga tggcttcttt
    48301 gactacttga ctgctttttt cgaatacggt cggtacttcc actttgatga tttcagcacc
    48361 gctgatttca tctggcattt tttttactgc ttcataggct ggattcactt tgtccccacc
    48421 aaatggatca aaacctgtta ctagtacttt catctgttgt tcctccgtcc gattgattta
    48481 acatatggtt atcttttatc ataccatttt ccttgaacag cgtaaataaa ggaaacaata
    48541 gtttaaataa cataacagat caaacttaat atattcttat aaaaaaatag tgttccacta
    48601 caatgttaga agaggttgcg acaattattc tgtcacaacc cctctcttct attatttaaa
    48661 tagaatcata taagcaattt ggaaaactag cataaataac gcaataaaca actggttttt
    48721 gatcactccg tatttgtctt tcatctccag catcgctaca ggcacgatat tgaagttagc
    48781 agccatcggt gtcagcaggg tcccacaaaa accgcaagtc aatgcaacca ttcctattaa
    48841 cgctggattc gctccatgac taaatacgaa tggtgcaccg atcccaaccg tcatcacggt
    48901 gatggccgca aatgcattcc ccatgattac cgtaaatatc accatgccaa gagcgtaaat
    48961 gatgatgccg atgttcacat ttccttctgg aacgatcgta cctactgcat tggaaatcac
    49021 tgtcccaact ccagcgcttg taaataccgc acctagagaa gctaaaagca ttggcaacat
    49081 gcttaacggc cctactgtgc ccagcatatc tgctgcatca tctaaaaatg tacttggtcg
    49141 attatctcga gaaaagaaca tcaagattag catggctgca aaaacaccga cgcccacgcc
    49201 gactaaagca cctaaattgg taaatagagc aaacaagatc gcaaagacac cgatactcaa
    49261 agctggaata aaaattttca ttcctagttt gtctgacatt ttttccatat attcttttga
    49321 tggaagccgg ctttctcctt tgctgacttt cttagcaatt gctggtatgg tcatcgcaaa
    49381 gatcaagcca ccgttcacga ttgccggaag ccatcttcct cctgcaataa ctacccctaa
    49441 gaccgtccag aaaaaggctg acccataacg atgaggattg gttttatctg ttaaatttct
    49501 tactccagtg taaatcaata cgagtcccat cacgatataa aggatctcca gtaatttatc
    49561 gcctaataaa atatcaggat ttgtaaaaaa gtccatctta ttgccccttt cctggataat
    49621 atttcttcgc taatttcttt tctttaagat agaagtagac acttgccaca actaaagccg
    49681 tgatagccac tggaacttcc actaaagcaa gctgtcccaa tgttacgtca tatcctagat
    49741 ctttcagtgt tgattggact agcaacgccc ctgctcctcc gatgaatagt acttggccaa
    49801 agaaccagca gacattttcc atagctgaag ccataccttt tagttcttct tcatgcttag
    49861 gatggacttc taaccctttt gattcgatgg tccccaatgc catcggtaaa atgattggac
    49921 gaacaaatcc agcaactcca ccaaaactca cgttaaaagc cgcaaagatc attcgaaaga
    49981 tcccataaat atctacaatc ataccagcag atactttctt gaatcgcttg atcaaggaag
    50041 ccgctgattc tttcagacca tttctttcaa gcgttcctgt tgccaacata atgatgataa
    50101 aaatcgccat cccgcgattg tttacaaaac ttgtacctaa aagttctaac attccttgaa
    50161 tgccaagacc gccagtcaaa gctgtaacaa ctaaagcaac cattacgatc aatatcgagt
    50221 ctaatttaaa tgcaaacccg agaataacaa tcaagacgcc taaaaggcta agataatttt
    50281 ccatatattt tcctccataa aatgacaata tttttttaat tataaagcaa aacacataaa
    50341 aaatatagtt gttttctcac gaaatagaca ctatttttaa atatttttcg ttattttttt
    50401 atcacaaaaa ttatcttact tattgtaagg taaagctttt tttaatttat tgcccgataa
    50461 tatatagaaa taaggtctag ttactgtttt ttttaaatga ttaataaata acaacttctt
    50521 tctatgaaat tgcaaagcat tcatcttctt ttccgctaac gatatatccg tcagtgcttg
    50581 gtacacttta ctaaaaagta tgagattgcc gatatctgga taggtgtgct atactacaga
    50641 aaaagatata cgatctgcca ccgggtagga taaagaggat gatcattcca ttaggtcttt
    50701 taagggatga ttttcctctt tttgtgtatt tttttatagt taaggaggaa tgtaagtatg
    50761 gcatggatgg aattaatcat agcaggaatt ttggaagtat tctggtcaac gatgatgaaa
    50821 tggagtgatg gtttttctaa aatcaattat tctttttaca cagtgattgg catgattgct
    50881 agtttttact ttttgtcaaa ggcaatcaaa agtttgccga tgagtctctc ttatcctatc
    50941 tggacaggga ttggcgcagt tggttcggtc ataattggtg tggtcttgtt tcatgataag
    51001 ctgaatcttt ccacttggtt ctttgtgggg atgctactca tcagtatcat tggcatcaag
    51061 attactagcg gccactagac acttggaata agtactgatc agaaaaaata agccttttta
    51121 tttaatattc aattttttta tgaaaaaata agaaataagt ccaatgacct agcgacttct
    51181 ccactcatca ggtgtatgct tgtactatct atagaaaagg agtgaatatt tttgaaaagt
    51241 ctttcggtcc aagaattatc caagaacttt ggtcacaaac aagccctcag cgatgtcagt
    51301 tttagcttat cccctggcaa aatcgttgga ttagtaggtc ctaatggcgc tggaaaaaca
    51361 acgatcatga aagctatttt aggactgatc cattactcag atggaacaat ctgtattggt
    51421 gaaaatgaga tttctccctc tagtcataaa gggttggaac aagtaggagc attgatcgaa
    51481 tacccgggta tctatccatt cttaacaggc tatgatcatc tgaagttatt ctctgaaacc
    51541 aacgatgtat ctgctatcga cactatcgtg aatcagctca agatggaaaa gtacattcac
    51601 aaaaaagcga aatcctactc gttgggaatg aaacaaaaat tgggaattgc tcttgcctta
    51661 ctgaaccatc cgtctatcgt tattttagat gagccgatga acggtttgga tccacaagca
    51721 acaagagatg tgcgaaaaat cattaccgac ttggctactc agggcacctc tttcttgatc
    51781 tccagtcact tactcagcga gcttgaaaaa atggtcgatg agctgatcct gatcaatcaa
    51841 ggaaagatca tcaaacaatg tacaatggct gaattgaacc aaacagcgca agatttcatc
    51901 gttatctcta caacaaatga tctagctgct cgaacgatct tgacagaagc tggatatact
    51961 ttggaagatc ctgataaaat caagctttta aaagaaaacg aagaattatt aggaaccgtg
    52021 atccagctat tgtctgcaca aaatatccat gtgacagacg tccagcatct gacgaatgat
    52081 ttggaatctt ctctattgga aattctggat tcagtaaagg gggaagaaga aaaatgacat
    52141 tgcttgtaaa acaagaatta tttaaattga tcaagaaaaa gtcaactgct gttttatctg
    52201 ttctattagt tgttttgctc ataggaacag cacttctagc caaaaaatac acgacgatca
    52261 ttgatccagt tgaaatgact gctcagcttt ttagtgccac atcttggatt gtctttatca
    52321 tgattgcagc tgcaagcacg atcatttcga tggaagcaca atatggtaca ttgaaaaatc
    52381 tcctttatcg aaagtattct cgaggagaaa tattagtaag caaatggatc acattagtta
    52441 tttattctgt ttatttatac cttttagcta ttattgtcac tgtgttgatg aaactgattc
    52501 ttttcccttc gatttccttc acggagaagg tttctactgg tcaaacactg atccaaagct
    52561 tgttcactta tactttgggt agttatatcg gtttatggct gattttaagt ttagtgttga
    52621 tgattgcttg ctttatcaat agttccggtg catccatctc agcaggaatc gtcttttatt
    52681 ttgcttcgtc aatcatatct ggtatcctta ttgcactcat ccaaaaatgg gagtggatca
    52741 aatggaatcc gatcagtatg ttgaatctgc aaaaccaaat tggaaacgaa gagatcatga
    52801 agcaattgac tcatctttct actaatcaaa tgctattcgg taatttagct tacatcgttt
    52861 tgttcttagc attaggatat ctcgtattta agcgaaaaaa tgtatgatga ctcatcaaaa
    52921 aagaggctgt gaaagagacg ttcagcctta ttgccgattg gctgtctctt aaacaccgtt
    52981 tattctgaaa aaggagctgt gacaacattt gtgtcacagc tcctttccta gtatgttttt
    53041 gaataaacga caggctcaca acctctcttt atacttcttt tatacttcta tacgtgaagc
    53101 atcccagtgg caaataaaac cattgcaatc actccgacca tcgtcacacc tataagtaaa
    53161 atcttatcta agtggatatg ttgtacaggc tcgttttgct ccttacgtgc tttgaggtaa
    53221 aaataaatgc ctggcaagaa aagaacaaga acaagcatta cttcattaaa ggctacgact
    53281 agcatagccc atacttgaaa ggcacttgct aaaagcccta ctaaaaattg gacccattct
    53341 ttccgctgat aagaaagttt catttggtac aatcctaaga aaagccacgt gaagaaaata
    53401 gctgctgtac caagtgtgta agcaaagtta taagcactgt cagtgaataa taatgaaagt
    53461 aaaaagacat tcgtacataa cgtcgtcaat acgatagcat aagttggtgc cccatttttg
    53521 ttgagttttc cccatgcttt aggcaaaagt ccgtcttcag ccatgtttcc cattgtttca
    53581 atcggtaaga tcgtccatga gagccaaaca ccaactaaag aaatgatcaa accgccgttg
    53641 atcacgactg ctccccattt accaaccatc atttcaaaca catagcccat agcaggctgc
    53701 gccttgatcg tttgcagctg attcatcgtc attgtcccat atggaagcat ggaaaccaag
    53761 acgtaaataa taatcaagcc gaatatccct agaatcgttg ctttcccaac atctgattgt
    53821 ttttttgctc gtgaacctac gacagaggct ccttcaatac caacaaatac ccaaagcatc
    53881 accatgatgc aactcaatac ttgactggaa aacgggatcg gctgtccatt cgcattcaat
    53941 ataatgtcgc tagaaaagtt atcaatgaat tgttggatcg aaaacgtgct gatagctact
    54001 acaataaata aaaataatgg cactaattta cagaatgtga cgatagcatt gacgaaacta
    54061 gcattttcga ctccccgatt cactagccat gcatatcccc ataaaaagac tgtactcatc
    54121 acgatcgatg ccagattttg cccaccttca aatactggga agaaatatcc taatgcgctc
    54181 atcaacaatg ttgcaaaagc tacgttgcct aaccagcatg tgagccagta accccaaccg
    54241 ctgataaaac cagcgaaacg gccaaaacct tcttctgcgt aactaaagat cccgcctttt
    54301 aaatctggac gttttttatt gatattattg atcgacaagg agagcatcaa cattgctgtt
    54361 cctacgagta cccaactgaa aatagctggg ccgccagccg atccggagat gtccgtcata
    54421 ataccaaata cgccacctcc aatcgctgaa ccaattacta aggcagcaag tggaattaaa
    54481 ccaattcctt ttttctgttg ctctgtatcc atgtaagcat cctccaaaat aaaaccgctt
    54541 ttatcaaaaa gtataacaaa ccttttttat ttttacttaa ttaataaaaa ctttaataga
    54601 aatataattc taccggcttt tttctcatta tacaagcaaa gcgcctagtc cctttccaaa
    54661 ttacaccacc aaaaaactta aaaaagatgc tatactaaaa ggaaagaatt ggaggatgat
    54721 ccatgaacat tttatatata tcgatttcag gaaatacgcg tgcctttgcc aaacatctag
    54781 cagaatatgc tgaaaaaatg catgcagaag atcctgtcaa tcctgaagtt actttaaaag
    54841 aaatccatga aaatagtgat tttacgaaag aaacagaacc attttttact ttcgttccta
    54901 cttatttaga cggcggaaat ggtttagata acggtgatac agaaatcttg accgaaacga
    54961 tgcgtgaata tctggaacat gaagacaatc ataaactttg tcttggtgta gtcggtagcg
    55021 gaaataaaaa cttcaataat cagtattgtc taacagccaa acaatatgca caaacatttg
    55081 gctttccttt cttggcagat tatgaattac ggggaacacc atctgatgtg acacgaattt
    55141 atcagatttt agcagaaaac aataaataat aaaaaagaag aagctgaaaa atagatttca
    55201 gtttcttctt tcgtttctat tgtttctatc atattaagct ttgacatcca tcacaggtgc
    55261 ttttgctttt gctttacctg ttttttccaa gacaaagttt tttacacgat ccatattggt
    55321 taccaagacg atcatggatg tttctttgcc tgctgctttg atcgcttcta agtcagcttc
    55381 tgctacaagc gtatcaggtg tcacttgctg cccttctgtt actttcacat caaatggcgt
    55441 accgcctaag tcaactgtgt tgattcccat atgaagcaag atttctaaac catttggcgt
    55501 tgtgatccca atagcgtgtt tcgttgggaa gacagagctg actaccccag taactggaga
    55561 atagatatgt ccgttttctg gttctacaaa gtagccttca cccatcatct tttgtgcaaa
    55621 aactggatca cttgctttat ctaaagaaac aactgttccg tcagcaactg atgagaggat
    55681 agtcacactt tcagctgaag tttgaggtac tactttttca ggcacttcat ttactgtggc
    55741 tgtttcagtc gctaattctt ctttttctaa acggtcttta ggaataccga agaagaatgt
    55801 agcaacgaag ccaccagcat aagctgccaa taatccaagg atgtagccta accatttacc
    55861 gtcagagatc aatgggatca aagcggctcc tgaaggtcca atagcgatag ccccgacatt
    55921 tccgatcatt ccgatcactg ccccgccgat acctccaccg atacaagcag taataaatgg
    55981 gcgtcctaga ggtaatgtta ctccgtaaat caatggttcg ccgattccta ggatcccgac
    56041 tggtaaagct cctttgatca tttctgttaa ttctttatct tttttgcagc gaatccataa
    56101 tgccaatgct gcacccactt gtcctgcacc agccatcgca agaattggaa gcaatagcgt
    56161 acgaccagtt tcatcaatca tttgcacatg gattggagtc aaaatttgat gcagtccgaa
    56221 cataaccatc ggcaagaata atgtgcctag aacgaagccg gcaaatgctc caccaacgcc
    56281 aagtacccag ttgatcccac cgaccatgcc atcagaaatg aaacctgcta aaggcatgat
    56341 gaagaaaatt tcaatcagac cgatggcaat caatgaaaga gttggtgtaa cgatgatatc
    56401 taccgcatca ggtactactt tatgcagttt tttctcaacg attgacaata gccaaacagc
    56461 gaagatgaca cctaggatcc caccttgtcc agctgcaaga gcttcaccag taaataagtt
    56521 tttcagtggt gcttccggat tcatccctgt cagcatcaca acggccccga taactccacc
    56581 aagagttggt gttgcaccaa aaacttgtgc agcattgata cctgtataga taactaggta
    56641 gctaaacatc ccgtttttca agatgttcat cacatcgata tattgttgcc atgttgctgc
    56701 atcaagtgtt ccggctgtga ctaagtttgc taaaactgcg gcaatccctg ccacgatccc
    56761 agtaccgaca aatgcaggaa tcattggcac aaagatatta gaaatgtctt ttaataccga
    56821 tttgatttta gatggttttt gtttcgattt ttgtgccgct ttcatttctt gtgcccgttc
    56881 gtttacacgg tcttttccag atgctgatga atttgctgta gctgcactta cagaagaaag
    56941 tttttctcct aatttcacgc ctgccaaatc aaccatttgc tgtgctactt tgttcacttt
    57001 cccaggtccg atgatgactt gaagctgttc atcttctact acaccaagca ctcctggaat
    57061 cgcttttaat tcagagacat ttacaagatc atcattgatg atcttcatac gcacacgagt
    57121 catgcagtgg acaatgcttt ctacattgcc catgccgcct gcccctttat aaatttgttt
    57181 tgccagttct tccaaagtca gttcgttttt tgccatggtc ttttccccct cataaggtcc
    57241 cttttacaaa tccgtttgct tcagctaatt ttgcttgagc ttcctcttta tcactatttg
    57301 tcaaaatcat gacgatagcc agcttaacat tttgatctgc ttcttcaaag tacttttcag
    57361 ctgtttcgta atcagcttct gtcgcttgca tgatgattcg ttttgagcgt tcgattagtt
    57421 tttcatttgt tggtttgaca tcgaccatca agttattgaa tactttacct ataccaatca
    57481 tactgatagt agaaatcata ttcaagataa gtttttgtgc tgttcctgac ttcaatcgag
    57541 tagagcctgt caaaaattct ggacctgcat cgacttcgat tgggaaatcc gcgtgtttac
    57601 tgatttcggc ttgtttattg caagaaatcg ttcctgtgac agcaccgatc gattttgcgt
    57661 aatctaatcc accgatcaca tatggtgtac gaccgctagc tgcgatacca ataactatat
    57721 cattttttgt caaattcagc ttgattagat cttcttgccc tagctcataa gaatcttcgg
    57781 ccccttcgac agctacagtc attgcttctt ctccaccagc aattagacct atgaccattt
    57841 ccggttctac accgaatgtc ggtacgcatt cagcagcatc taacacacct agtcttccac
    57901 ttgttccggc tcccatataa atcagacgtc cacctttttt aaaggactca atcgtgttag
    57961 caatcactgg ttcgatactt gtcagttctt tttcaaccgc agcggccact ttctgatctt
    58021 ctttgttcat tagttgaacg gcttgagaaa tactcatctc atctaatcca aaagtttctt
    58081 ggtttctgcg ttccgttgtt aggttctcta aattgatttt gctcattttt atcttccttc
    58141 ttttcttata aattgatagt tcataccagc tttgatttgg ttgatcaatg gtagctcttc
    58201 tttgataact ttagctacta cattcacttt ttcatccgct ggcaaatcat atttggttaa
    58261 ttggatctca cccatatagc gcaaatactt ttcgttatct aaagtaatag accctttcat
    58321 acgcgtagct gtatttcttg ctgggatagg cggaatctct cgaaaacgtg catctgcgct
    58381 tcgtatgaca tctcttgcat cgtcttgccg attcgtatgc ttccctaata tatattcgta
    58441 aaattcttca tctacaggtt ccgtatggag caagactgtc tgttcttttt ggaaagaagc
    58501 aaattgctcc tgaacgtttt ctgacagacc tgcatctccg atgtaaacaa tatccgtgtt
    58561 acttgctaat agatctagag cgcctgcaag aggatggatc cctcgatgtt cttccaaagt
    58621 tggcaatcct tgatatagtg ggcctctcaa ctctgtatct cctggtacaa aaccttggac
    58681 aaggagacct tgaattttga gccattgatt ttttttctga taccattctt tgtccagccc
    58741 tgtttcggga cgtggataat aattatgcca agcttcaatc tgtgagaaat cagcttctgc
    58801 ttctttcaat tcatcgatat ctttaggcgt gatcgtgcta gcattcaaac tgattttcaa
    58861 ttgatgtgac cagtcggcaa tctgctgatt ggaaatatga taatccattc ttaaacctgt
    58921 tacaccaatt gctttcaaag gcgttagatc ttctaatgaa aaacccgctc gttccaatgc
    58981 ctctcctgaa atatcgacca tcaattctag tttattcttt ttcgcttcgc ttcctagttc
    59041 gatcaatcgc ttttgatatg ccgaaacatc atcttctggt atatgcatgg aagtgaaaat
    59101 accgacaaag ccattggatg ccatttggcg gatatactgt ttcttctctt ctgacaaaga
    59161 atcgttcata aatattgaaa agccaaacat attatccctc tttttctgta tccgtcttca
    59221 tttctatgac tagagtatat atctaaagaa acaaaatttc aatactttta ttaaaataat
    59281 taaatttcat ttctaaaggt tgagtttata ttatcaaaag aattgtcata acctaaaaaa
    59341 ggcactgcta agcaaaagca gtgccttgaa atattttatt taaataacac aaaaacataa
    59401 ttactcataa gaaaccaatt ctgtattatc taccatgaat gtaaagaacc cctcattagg
    59461 catcggatga aaataagcat tgatcactct tatcaaggca ttatggcaaa ctaacagata
    59521 gacattttct tcgtcttcga tgcattcttt caataaagga acgatccgtg catacacatc
    59581 taagactgac tccccatttg ggaatcgtac agcgaacgct aaacgtgctt tttgaaagtt
    59641 ctcatctttg cttggcagtc catcataatc cccaaaatcc atttctacca atcgttcatc
    59701 aacggtcagc ggcaagctga gacgatcagc aactgcttgt gctgtatctc ttgctcgttg
    59761 aagaggggaa tggatgattt tcgtgattgg aacaggcaaa tctactacct tttctgctag
    59821 tttctgtgcc tgcatctgtc ctttttcagt cagcggcaca tctgcccgtc cgcaaactaa
    59881 tccttgtgcg ttccaagttg tttctccgtg tctcgttaca taaagcatgt gattctctcc
    59941 ttcgttggca aagttcccct taaccatacc ttgttgttct tgagattaca agggttagat
    60001 tctctcaaga gaaataatct cagtagatac tttatccagg aaggtttgat catgttccac
    60061 tagtaacatg gcaggtttca cgttcaagat cagttgttct aattgttctt gattgaagac
    60121 atccaaataa ttcaatggtt catcccatgt atatagttca gctggctgtg ataaagattt
    60181 agccaattcc acttttttcc gttggcccat actcatctgc tcgatcttgt tatgaaaaac
    60241 atctctttcc atcccaagct ttcggaggtt gttcaaaaat gcttggtagt ctacttggtt
    60301 tttctctgca aattccgcca acgttcctcg attgtcttca taattttggc gtacataact
    60361 aatgctcaga tgttttggct gggatttttc tcctataacc ttgccgttga atgcccccag
    60421 aagataatgg ataatggatg actttcctgc accgttagga cctgaaatcg ccacccgctg
    60481 atgaggctcg attgtaaaat gaattggctc gaataacaga ttttcatacc ctaattgaag
    60541 atcttctacg cttaaaagtc gcttatggtg agacgcttgg ctattcatcg tcaaagaatc
    60601 gatatattcg atatctttta atagtttttc tttctcgctg atctgggtct ccatccgatt
    60661 cacgattgct ttggatcgtt tcatcgtccg tgcagcatca gcacccactg ctcctttatt
    60721 cactcgtcta gattcagtat cgatgaatcc gacttgtttc tttgttttat ctccttctcg
    60781 ggaacgagac cattcggctt tttcagctgc tgttttcttt agcctactga cttctttttt
    60841 caatttttca ttttgagcca tttcaaattc atcacgaagt tttttctgtt cttcatagat
    60901 agagaaattc ccttgataaa gttccagttg acttttttcg attgctaaaa catggtccac
    60961 tacttcatcg ataaatcccc ggtcatggct gaccacgatg aagccttgtt ttttcttttt
    61021 caaataagcc gctacttgtt ttctaccaga gatatccaaa tgattcgttg gttcatcgat
    61081 taacgggaaa tgagtgtcat ccacaaataa aagtgccagt aggacttttg tcttctctcc
    61141 ccccgatagt gtgctgaatt ctctccataa gatttcagga tctgtttgca tcaattggag
    61201 ctctctttcg atttcccata tctcaaaatc cgtaatatca tttaacacgt aataggttaa
    61261 acgttcttta tcttttgtct gttgcgggaa ataggcaaat tcttgctgat ggattacttg
    61321 cccttgataa ggtagtttgt tttgtagaat attcagtaaa gttgtctttc ctcgaccgtt
    61381 tcgtccgata agtcctagtt tccattgtgt gtcaaaattt agatttgctt gttcaaataa
    61441 taatgtgcct tggctgtcgt agccgaatgt cagatttttt atttcgattt tagacatttt
    61501 ccatcacctc gtaaaaaaag accagtccta ttttcagaac tggctaaaga ggatgcaagg
    61561 gttggataca cacaaaaaga cccatacatc gaaaaaacca agccaatccc gaaaatctgc
    61621 acactgcttc cttgtctcca caaggtacag tctgaatgca gctttcatca atcgacttaa
    61681 tttttcaatg cacggatccc tcactttgtc ctatatttga aattacgata gcataaagaa
    61741 aatgattttg tcaactactt cgggaggatg gtgaaaaatc tgctaagtgt ctgtcctaag
    61801 atttttgttt tttctaatgt ttgcctgtgt tccattgctt cttctaaacc tattggaccc
    61861 aaatgaatac ttaagacaat tgggagaaaa tcagagagtc cttctagctc ttggtctcta
    61921 cttccgcaaa tagcgattat tggttttcga tatttttttg caagcactgc tacaccgtgt
    61981 ggaacttttc cgtggatcgt ttgctgatcg atccgccctt ctcctgtaat gatgacatct
    62041 gcttgttcga tctttttttc caatccagtg atttggctga ctaaatcgaa accagaaacc
    62101 atcttcgctc ccaacaaaaa aagggctcca ccaataccgc ctgctgctcc acttcctgga
    62161 atatcatcta aatccacctc ccagaaatct tttatttgct gagcaatctt tcctgcttgt
    62221 ttatctaaga aagctagcgt cgtatctatt cctccttttt gtcttccaaa ttgccaagca
    62281 gctccttgtt gacctgtata tggattggta acatctgcag cgataatcaa ttttacttta
    62341 gaaacaagaa cgtttcttcg atcaaaatga agttttttag tagataataa aggatttcct
    62401 tctgtgtacc cttctaaaga agcacccaag gattggagta atcctagacc accatcgcta
    62461 cacccgcttc ctcctaaagt gacaataatt tgttctactt cttgaagcag tgcatctttg
    62521 ataagttctc ctaaggcata actggaagca agtcggatag tttgatccgt tggtttatca
    62581 agtagatcta accccaatgc ttgtgcagat tcgatgactg cggtattttt tccttgccaa
    62641 gttgtcaata aatagctgat ttttcgctga cggaataaaa gatccatccc atcaatggtg
    62701 cgccatgttc ccccgagcgc gtaatagatt gcttctgcag tattttctcc gccatctgca
    62761 atcggcacat tgatttttct tcctttacga tcttcccagc catttagaac tgcctgattt
    62821 agttcaaatg aagaagcact tcctttaaat gaatcaattg ccgccaaaat atccatctgt
    62881 atccctcact ttcttcttaa gtaagacact ttttttcatt tttttcaaac aaaacaatgc
    62941 tattttcttc catttttcta tatactaaaa gggaactcat tgataaagga gagaaaaaac
    63001 atgaaaatcg caatagctgg agccggagca atgggcagcc gaatcggatt gatgctacat
    63061 caaagcggaa atgaggtcct cttgatcgat cgttggcctg cacacattga agccattcgt
    63121 acaaatgggt tgattgctga ctttaacggt aaagaagtgg tcgcaaaact gccaatctat
    63181 tcaccagaag aaatcatcga aagcaacgaa cacgtggact tgatcgtagc attaacaaaa
    63241 gcgaatcaat tagatgatat gtttcgttcg atccaatcca ttattactga caatacttat
    63301 gttttgtgtt tactaaatgg attaggtcat gaagatgtac tggaaaaata tgtgccaaag
    63361 aaaaatatct tatttgggat cacgatgtgg acagctggtc tagctggtcc cggaaaagtc
    63421 acattgttag gtgatggaga aatcgaacta gagaacttgg aaccagaagg cgaagcattt
    63481 acaaaaaaag ttgtggaagt ctttcaagaa gcaaaattaa atccgatcta tagccataat
    63541 gttcgttatt ccatttggcg aaaagcttgt gtaaatggaa cattgaatgg tttatgcacg
    63601 attttggatt gtaatattgc tgaactaggc gcgcaaaaaa cggcagagag catggttcga
    63661 acaatcgtat ctgaatttgc ttctatcgca gcaaaagaag gaatcatatt agatcaagaa
    63721 gaagtgtacc aacatattgc ttctacttat gatcctgaca acatcgggtt gcattaccca
    63781 tctatgtacc aagacctgat caaaaaccat cgtttgactg aaatcgacta catcaatggt
    63841 gccgtttggc gaaaaggaca aaaatatgat attgctacac catattgtgc ctttttgacc
    63901 caattagtcc atgcaaaaga aggaatcctt ggcgcagaat aaaaggctct ctgatgagaa
    63961 tcagctgaat cagcagctgg ttctcttttt ttaagcccaa tgaaagatca aaaagaaaac
    64021 acaactctca tgatgccata agaattgtgc ttgtttgttt cggtacataa tctcttcaaa
    64081 atgtaggttt tttatttatt ttcaacagag gagaggtcat attcgtattg ctcataaata
    64141 gtggaatcgt tagtgataaa tcgttttgcc caattttctg catcataaaa ttccaatagc
    64201 tctgatggga ttggcttaaa aggtgtatgc agaaattccg gtaattcatc taaatcacgt
    64261 tctcgaagca aaaaaatatt ttcaggacga taaaaatgat aatgagcaat cgcttgatta
    64321 tccgtcacta gtttcttttg aaaatacata gattcaaatg tccgcaaagt cactccttgc
    64381 tgaccctccc gcaacagttc cagaatcccg cgcgattccc ctgttttttt caggtactct
    64441 tcataagcaa gatatccagg ttgttcattc cctcgatgtg gaagaatgaa atagttggtc
    64501 gtaacatctc tttttataaa ttcctgctta tagctttctg ctcgttcttt tctcccatta
    64561 ttcgttgcac caaaaaatag atccgtcttt ggttcgctag aagaaaaatc catatgtttc
    64621 gaataaaatg aactattatg tttcagccca agttcttttg cttccaaaaa atcaaaatga
    64681 taaatctcat cgattgccgg ttcatcttgt gcctgcttca gcatcgcctc gtgttctgct
    64741 ttgaagtgat tccaaaaaaa taacacaatt tttgcattgg taaatgggcg cacgcgtcga
    64801 gccatctcca tattaaatcc ataatctaaa aaaacgatca gctgataatt tgccaactgt
    64861 tgtctagctg atttaatgaa ttccgactgt agtaaatctt ttccggacca aacatctaaa
    64921 gagcggatgg aaggcaaaaa ataaagtgat ttattttttg caactagcag tacgtcattt
    64981 ttgttcatct tttccgcctc actttctctg tcactttttc ctatgatagc ctgtttaaat
    65041 agtaaaaagc cagtaaaacg cttcctatat ttgtatgaaa atttaacatt tgtatgaaaa
    65101 tatgatgaaa taaatcattc ttctattaaa attcgcctaa aagttttctg aatagttgta
    65161 attgtctgaa aatttgttat cattagtcat tgttaaatat tgctatttat tcttaatata
    65221 aattttgatt gtgaatttaa aagaaagagg tcatttatgg aagataaaaa attgaaaaaa
    65281 caacttagct ccagacatat caccatgtta gctttaggtg gagcaatcgg tgcaggtcta
    65341 tttaaaggaa gtggcgaagc gattgggatc gccggccctt ctgtattgat tgcttttttg
    65401 attggcgggc tgattttata tatcgtgatg aaaggtctgg gaaaaatcgt tttaagcggt
    65461 ggcgacacgc atcacggatt atctggtttg atacgccctt atctaggtgc tcattctgct
    65521 gattttactg attgggtcta ctggtctatg tggattatca atatcatcgc tgaagctgtt
    65581 gcagctgctt cctttttgca gttgtggttc ccgcacattc cagcctgggt atttgttttt
    65641 atgttggctg ttttaactac gatcatcaat ctttattcgg tacggttatt cgcagaaaca
    65701 gaatattggc tggcttttgc taaaatcagt gtcattatct tactaatcat ttttgctact
    65761 tatcttgtcg gtcagcaaat gttgggcaca ggcgttttcc ctacccttca gcaattgact
    65821 gaccatggtg ggtttactcc tcatggtatg aagggaatca tcagttcttt gcttgtagtt
    65881 atctattctt acggcggttc tgaactgatt gctatcacgg taagcgaagc agatgatcct
    65941 aaacgtgcga ttcctaaagc catcaaaggt gtcatgggaa gaatcatttc cttttacatc
    66001 attcctttgt ttttgctttt gattcttttt ccttggaata ctttagcagg cacgaatgtc
    66061 agtccttttg tgatggtatt tgaaaaaatg aatatcccat ttgcagcgga tatcgtcaat
    66121 tttgttattg tccttgcttt gttctcatct atcaattcgg gtgtgtatgc atcttcaaga
    66181 attttgttct tccgtttgaa ggatcgaaaa ggttcctcta gaaaactagc tgttttaaac
    66241 aagcatcaag taccgcaacg tgctgtttta ttttgtacca gtgttcttta tcttggtgta
    66301 gctctttctt attttgtcgg tgacaaatta tttggctatc tggcaggttc cctttcgtat
    66361 acagtattat tgatctggat cattatcagt gcggcatcct ttgtactggc actaagaaaa
    66421 ggaacattat gggataaagg aatcagcttt tttgcattag ctgtcttagg attgattttc
    66481 cttggtatcc tgttcacgaa ctccattggg gtaactgtat tgactggcct gctttacctg
    66541 ttcatttatt tcagttatca aaaaaagaat gatgcgttcg tattgacgaa tgaatgaaat
    66601 cgatagaaaa ttttatttta tttatgtgga atagatggaa ctattgaaga aaggagttgt
    66661 gacaaaagtc ttgttgcaac tcctttttcc gaataaacag tctcatgacc tcttggtaaa
    66721 cggtgttcaa aaaccctctg tgcaaaataa ttgattgttc tccatgctca tgacatgata
    66781 gaagaaagga atgaaaaaaa ggagtttgtt ttaaatgaaa aagtattgga agtttttgtt
    66841 gatgatcggt gtttcaacgg tagttatgtt tggtatgatg tacttgaatg tctatgcgct
    66901 cgatcatatc ttcttcagtc gtacacgagt attcatggcg ttgatgatgg gtgcagtcat
    66961 ggcagtcatc atgctgttgt tcatgtggaa aatgtatgaa aacaaaaaga taaatgttat
    67021 gatcttagcc gctagtcttc ttgtttttgc cggttccttg tttatggtac gaagccaaac
    67081 tactgtcaac gacacagctt ggatgaaggc catgattcct catcattcta tcgctatcct
    67141 gacaagtaaa cgagctgatt taaaagatcc tgaagtaaaa aaattagcgg aagaaatcat
    67201 ccaggcacaa gaagaagaga tcgacaaaat gaaaaaaatg atcaaagaaa tggaatgacc
    67261 attatccgtc caaataaaaa aagaggatgt tccagaagtg atcagcttca agaaataaga
    67321 agaagctact tctggaacac cgtgaataag gggttgtgaa aaagctgccc tgcatcaagt
    67381 aataagaaca gccaaacaaa aatagcttct cctatttttc gtttggttag gcttattacc
    67441 gcagatgcaa gcttttgaac accgtttatt cgtaaaaggg attgtgacaa aaaaagtctt
    67501 gtcacaatcc ctttttatgt ttttattgtt ctaattgcgc tgtcttgctt actgcttctt
    67561 gcggtttcac aaattttttt gagattcccc aacctgtgaa ggcactgacc atcgaaaaca
    67621 caggagaaag caaactgaaa aatacgaatg gcaagtaagt gagtgtagga ataccaaatg
    67681 tacttgctac gaaacttccg gcaattcccc aaggcactaa gtagttgatt actgttccac
    67741 catcttctag cgttctacct aatacagttg gatcaaatcc tgctttttca taagtttctt
    67801 taaatgcatt accaggcaga ataacagata ggaattgttc accaataaaa atatttactc
    67861 cgatacttgt catcaatgtt gtaaaaatca attttggtgt gttcgtcatc tttcttgata
    67921 ctcgttccat cacggttgag atcaagccaa attcgatcaa caatccacct aatgacaaag
    67981 ttagaataat caatgacaca gtaggcatca tactttcgat tcctccgcga ctaagcagtg
    68041 aatcgatttg ttggtttcca gtatttgaaa caaaccctga ttcgatgacc ccagccaact
    68101 tcgttaagga agtttgtggg ttttgaataa aaatcattcc tactgctaca gcgatattca
    68161 acaaaatcgt caaaattgcc ggcacctttt tccatgcaca cagtaacatt aaaaataaag
    68221 gaatcagtga ccagattgaa atagtaaagt ttgcttctag aacatcagtc acttcacgaa
    68281 tagatgaaag acttgcggct ttacttgtgt gccctaaaat catgaataaa aagaaagaaa
    68341 caacaaatgc cggaacagtt gaccacatca tatgcttgat gtgtttgaac aaatcggcat
    68401 caacaatagc tgctgctaga tttgttgatt cggataatgg agacatctta tctccaaaaa
    68461 cggcacctga aacaatagct ccaacaacca gcgctggatt taggcctagt gttgtcccaa
    68521 taccgaaaaa tgcaatccca atcgttgaca taacagtaaa ggcactccct acagcgctac
    68581 ctacgattgc acacacaaca aatacagaag ggacaaacca ctggacactg atcaatttga
    68641 acccaatgac cattagagtt ggaatgatcc ctgcttgtat ccatacagca atcaatgaac
    68701 ctactaaaat aaaaataaag attgggatga ttcctggttt gatgccattg atgattcctt
    68761 cgtgcagcca atctgtcggg tatcttttta tcactgcata caacatgacc attccgatcg
    68821 ctgctaagat cgtgatatta ggtgagacct ttaatccgac aacgccaatc gcaatgccta
    68881 aaacaataac cattaataca agtgttgctt ctaaaaaact tggtgttcct ttttttccca
    68941 tgataatctc tcctttttta gttgttctta tgttctaaaa aagttaagat atcggattac
    69001 tccgccgcaa ttcatccgct attcctcctt tataaaaata aaaagacctg ttttaaacta
    69061 aggacgaatg actccgcggt accaccttaa ttaaaaacag atctgttttt cactttcaaa
    69121 cttttattca aatgtatgga ctttccatgt aattcgtcaa ttaggcttga tcggttcaca
    69181 gcgaccaccg actttctgaa caaaacacct aaccgctact gcgtgaaaag ttgacttgta
    69241 tgaagtttac cttccataag atcatttgtc aatgaaaaag aaaatatttt ttcatttttc
    69301 tgaaaattat ttttataact ttcacacaca agtttatttt ttactagaaa gtagcaccct
    69361 cttgtttttt tcttgctact atttcttgat gttcttgctt gattctttct aatagctttg
    69421 gctctttcaa cagatcaaga gctgtattgg cgagtagttc tgctgcaatc gcaatagaag
    69481 caaggccttt gtcactttta gcagcagctt tgaattcttc tgtgtgtccg gcaatatatg
    69541 tctcagagat tgctaccgta ggctggattg ttggtatgac ttggctgaca tttcctacat
    69601 cagaagaacc gagacttgtt ctttgttccg tttctatttc ttcatctgga acacctgctt
    69661 cttttgcatg ctggaagaat aagtcatcaa aagaaggagt aacgatgaca tcatcaactg
    69721 cattttggaa caatccaaac tcaaaagtcg tgcccgtact tatcgcagca cctcgtacga
    69781 tattttccac tttttcatat actttatcta atgtttgccg atttcctgca cgtaaataga
    69841 aacgtccagc agcgtaatct ggaatgacgt tggcagctac tcctccgtct gtaatgatcc
    69901 catggatatt gacatctttt ggcaattgca agcgtagagc gttgattcca ttaaacactt
    69961 ggatcaatgc ttccaaagca tttactcctt tttcaggtgc tgctgctgca tgggaagcga
    70021 caccgtaaaa tttgatgtcg actggatcat tcgctaaaga ttctgtcgtt ttcccataac
    70081 gaaaagctgg atggacgcat aacgctacat cgacatcctc aaaaaaacct tctcgaacaa
    70141 agctgccttt agctgatccg ttctcgcccc cttcttcccc tggggtgcca tatacacgga
    70201 tttctccacc agtttcatca ataaattgct ccactatgct ggcggctatt acggagtaag
    70261 taccaaacaa attatgcccg catgcatgac caatacctgg taaagcatcg aattctgcca
    70321 aaaaggcaat tgtgggtccg ggtttattgg aaatataacg tgcatcaaag gctgttcggt
    70381 gtccagctac ttctttttct acccaaaacc cttctttttc taattgttta atcaacgctg
    70441 ctgaggaata aaactcatag ttacttactt caggatgttc gtggatatct agagcaagtg
    70501 cttgatattc tggtaaacga tattggatta gatccttcaa ttggtttgtt gagattgttg
    70561 ttgtcataaa aaattcctcc tatgctagtc atttttctta ttttctcccg aatgtttccc
    70621 atgcaggcac gcttgatcct tttgatgttt tctcgattac tttgactgtg tcttctgttt
    70681 gataagcgtc tactattttt tgatacgttt tatttttttc atcttctttt cttgcaacga
    70741 tgatattcac ataaggacgt gcatggtcat ccactggttc taagaagatg gcatcagaag
    70801 caggattaaa tccagcatct acagctacac cgctattgat cactgaaatg tctacatctg
    70861 acaaagcacg tgctgtttgg gaagcatcta attcagaaat gtctagattt tttctattct
    70921 cggtaatatc agaaacagtg ggcgcttgtc cttttgcctt atccactttg atcaatccag
    70981 cagtttgcaa taacagaaga gctctgccgc catttgtaac atcattaggg attgctactt
    71041 ttgctccgtc tttgatatca gctacatcct tcaaagtgtt agaataaatt cccagcggtg
    71101 cattgacagt atttccgatc gatactaaat cagttccgtg ttctttattg taattgtcta
    71161 aaaagaattg atgttggaaa gaattcaaat caatcgatcc atctgctaaa gccgcatttg
    71221 gttgattgta atctgtaaat ttcacgtatt ccaaattaat gttctccttt ttcaaacggt
    71281 ctttcacgtt gtcccataca tctgtatctt ctccaataat tcctagtttt acggtagttt
    71341 cttttttgtc agttgtatct gcttttcctt ggctacaccc tgccaaccaa ataattgcta
    71401 caaatgtaat gactacaaaa cgaataattt ttttcatttt ttctcctcca ctttcaatgt
    71461 gtaatttttt taatcagttg attactgata aattgactta aaaaaactaa gattagaatc
    71521 aataatgtag ccacaatcgt tacatctgtt tggaatcgat tataccctct cgatatagca
    71581 agattcccta atccgcctgc acctactgct ccagccatgg tagtcagtcc gatcacgttg
    71641 atgatagtca acgccgagac ccgaatgata ccaggcaaac cttctaacaa atacacacgt
    71701 aaaataatac cgattggact ggttcccatc gcttctgccg cttcgatcac cccaggatca
    71761 acttctagca gtgcgttctc gatttgacga gcaaaaaacg gaacaactcc aaaaatcaat
    71821 ggcactaaag ctgctttcgc accaatcgtc gttccaacta agaaacgagt agtcaatgct
    71881 aaaagagaaa gcaagataat gaaagggatg gaacgaatga tattgatcag cttatcaagt
    71941 atttcaaata gcagacggtt agctagtaat ccattagggc gtgtcactac taacgtcaca
    72001 cctaagatga ttccgatcat cccgccaatg aatgctgtcc aaaaagacat atatagtgtt
    72061 tgcttcgtcg cttcgacaaa ttcatccgga atcaaataaa cattgggcaa atatgtttta
    72121 aagaaatcag tcattttatc ttcctccttc gatcactttg atacgactat ctaattcgtt
    72181 tttttgtaaa atatttattt ttacaccaga tttgatcaaa taatccaatg ctttttgccg
    72241 ctgtttggtt tctccagcta aagtaacgat caaactccct aacggcgttt cttgtaataa
    72301 ctctacattg ccatataaaa tattcgctgt tacttgatat ttgctgtaca gatgagcgat
    72361 tagaggttcg ttcgtctgat ttccaatata acttaattcc accagccatt tattggcgat
    72421 ctgatcggca aaagcagaat gggcaatgat cgtttctaat gcttggtcaa gatgagtagc
    72481 tgttcgaata aaatctttgg tcaattcttc ttcaggattg ctgaagatct ggatgctact
    72541 acctttttca atgattcttc catcttccat aaccgctacc ttgttgcaga tttctttgac
    72601 aacttgcatc tcatgagtga tcaggacgat tgttaaacct aactggcgat tcaatttttt
    72661 taacaatgca aggatctgaa gggtcgtttt cggatcaagt gcactggttg cttcatcaca
    72721 taataatacc ttaggttcat tcgccaaagc tcgtgcgatt gctactcgtt gtttttgtcc
    72781 ccccgacagt tgtttaggat aagcagatgc tttttcttcc aaaccgacaa gttccagtag
    72841 ttcattcact ttttgacgac gttcctgttt cgattttcca gaatacttta aagaaaaatc
    72901 aacgttgtca aaaatagttc ggctttccat tagattgaaa tgctgaaaga tcataccgat
    72961 ggcctttctt tcttttcgca attctttggg agagagctga ctcaaattcg tctgattgac
    73021 aatgacttct cctgctgttg gtttctgcag caaattcatc acacgaacta acgtactttt
    73081 ccctgcacct gagtaaccga cgattccata aacatcgcct ttttcaatcg ttaaatctac
    73141 agaatctact gcctgtatct ctttttcttt ttgtttgaaa catacagaaa catctcgcaa
    73201 ttcaatcatt aaaattcctc cttatctaaa aaaagcgtcc tcaagaaaat gaaaatgtca
    73261 ttttcttgag gaagcttttt tgcgtgttac cacctcatgt tcaagctgtg ttcacacaca
    73321 actcctcttc aagtacgatc atactctagc aagatatcgg tcgcagccgt catcgcctta
    73381 catctatgct cgggatgaat tgctcgatgg ccattttcca atagtcgttc cttgcttctt
    73441 ctcagctacc gaagctctct gtcaaaggtt cttctatcgt acttaccatt tcaatgcaaa
    73501 taatattcaa aaaaaaatcc ttttactaac ataaactatg tcagtaaaag gacgacgtat
    73561 cgcggtacca ccttttttcg gaagtttcct tccctcaagc ccaacatctc aaaaagagag
    73621 attggcgttc gttttaacgg tcgaacagtt ccgaatttgc ctacttatcg acaaattatt
    73681 ctccaaggcc attttcagct tttcttactt gactcttctc accagccaga gcctctctgc
    73741 aaagtttcca aacttacttt ccttttcaac gaaatcgata ttttgttgtt gggattaatc
    73801 tacatgagga aaactaaaaa gtcaagcacg aaattcaaat tattttttct atatttattt
    73861 ttctgttttt ttatctaaca tttcaataac agttcgaaga tcttttcctt cagcaagaag
    73921 tttcaatttt tccttttctt cgacggtata atttcggaca aaactggaat caggtatcaa
    73981 aacaacgcct aatcctgctc gtgaagcagc tgttgctcct actaaagaat cttccactgc
    74041 aaaggctgaa ctagcttcta atcctgttcg ttccaaagct gtcagataag gaatcggtga
    74101 aggcttgttc tccgacactt cgtctccgaa tgtaaacgtg tcaaagtaat cagctaattt
    74161 aaagtgatcc aagatatctg ttgctctttt cgtaacagtg gtcgtagcaa tgcctagttt
    74221 catatgacgt tcttttaagt ctgccaatat ttcttttgca tatggtttta agtggatggc
    74281 tccgcttgtc agctgttgat aaaaatattc ttcacgcttc gctcggactt cctgtacttt
    74341 ttcagggcta cctgctgctt tcactaaaat atcaaaactt tgtttccagt tttttccgcc
    74401 ccaagcgtca acgatttctt ttgggatatg gatatcaaat tgctgaaatc cccaaagcca
    74461 gccatcacga tacgtttttt ctgtgtcaac taacaaacca tctaaatcaa atattgcacc
    74521 tttcatctat acattaatcc tttccaaaac aatacacata gtttagcacg actggtccaa
    74581 aaataacaga agcaaagaac cagccttctc gtttataaga gttcttggaa tcgatggata
    74641 tagattttct tcacagctgt cacaagcgcc agataagcga tgactgtagc aaataaccat
    74701 aaccagtaat tgccaggaag tggcatcaag cctaattcag caccaaaact tgtaaaagga
    74761 aggacagaac cgacaataat tcctaatgta gtgataacaa acatggcaaa tgttacgttg
    74821 ctttggataa atggtacttt cggtgtacgc agtgcatgga gcactaaggt ttgtgtccat
    74881 agtgattcga caaaccatcc tgcatggaat aatgcgatga aaatcacttg ctgtgaacta
    74941 tccaatgtat ggaaacttcc gccaactaca gcaggacaaa taacaaaata catcaacaag
    75001 taagtagtaa tatcaaatat cgaacttgtt gggccaaagt aaaccatgaa tttcccaata
    75061 ctagatgcat tccatttttt tggctcgtcc aaatattctt tatccatccg atcccatggc
    75121 aaggaaatgc aggaaacatc atagattaga ttcaaaaaca gaagttgtaa aggcagcatt
    75181 ggtaaaaatg gcaggaacat acttgcaatc agcacggaaa acatattgcc aaaattagaa
    75241 cttgctgtag ccttgatata tttcatgata ttcccaaaag tttctcgtcc agaaagaagg
    75301 cctctttcca aaatcgtcaa atctttttct aaaaggatca cgtctgcaga ttctttcgca
    75361 atatccacag ctgtatctac agaaataccg atatcagcca ctttcattgc aggagcgtca
    75421 ttgataccat ctcctaaaaa tccgacagta tgaccatttt tacgtaaagc tgtcgtcaaa
    75481 cgtgcttttt gctgaggatt caattttacg aatacttcat ggtcttcagc tacttgtgct
    75541 aattcatgat cactcatttc cgagattttc tcaccggtaa ccaattcatt gatctctaga
    75601 cctacttgac ggcacactga acgtgtaact aattcgttgt ccccagtcag aacttttaca
    75661 gctacaccat gttctttcag agctttcaac gcttgtttcg ttgtttcttt tggtggatca
    75721 aggaaagtaa gataaccaat caaaaccatg tctgactcat ctttgactga aaattctcca
    75781 acgacgcttg gattggtctt ttgtgcgaca ccaatcactc gtaagccatc ttcattaagt
    75841 gactgtactt ttgcaagtac ggcttctttt cgttcttttg ttaatggtgt aacagtaccg
    75901 ccaagatcaa taaatttaga aatgttcagc atttcttcaa tcgcgccttt tgtgatcatt
    75961 tgtgttttac cagctggatc agcaaccaca acactcatac gacgacgttc aaaatcaaaa
    76021 ggaatttcat ccactttttg ataattgatc ttatctgtat ctaaagtttc tgttgcttca
    76081 tcaatgatag ccacatctaa caaatttttc agccctgttt gatagtagct atttagatac
    76141 gcatggcgca aaacacgatc atcttcattt ccttcacaat ccatatgata ttcaagaatg
    76201 attttatctt gtgtcaatgt ccccgtttta tccgtgcata acacatcgat tgcaccaaag
    76261 ttttggatgg cattcaaatt tttgatcact gttccttttt tggccatcac acttgctcct
    76321 ttgaccaaat tcgtcgtaac gatcattgga agcatttcag gtgttagacc aactgctaca
    76381 gatagtccaa aaagaaaagc ttctagccaa tccccttttg taagcccatt gatgacgata
    76441 actgctggag ccatcaatga cataaatttg atcagtagca tggatgtttt atggatgcct
    76501 aattcaaagc ttgattgaat tggtttttca gatagcgttt ctgctacatg accaaatagt
    76561 gtttcatttc caacagaaac aatgattcct tccgcacttc cacttatgac attacttccc
    76621 ataaagacaa gattttcgta acttgtttcg ctttgctgat cgtcttcaca tactttcgca
    76681 tgcttttcta ctggatagct ttcccctgtc aatgctgctt gggaaatgaa taaatccttt
    76741 gcggacaata aacgcatatc cgctggtatc atatcccctg ctgaaagccg aacaagatct
    76801 ccacagacga tttcttccat aggaatctct gtgtactttc cattacgttt tacagctgcc
    76861 gttactttca caagtgattt cagtttttca gccgcttgat tggaacgtac ggactgaatc
    76921 aacgtcattg tcccgctgac gatgaccata gtgaagataa tggctacacc gaaaagatct
    76981 ttatctccag gagctgctaa tacatattcc gtgatgaatg aaataattcc taatgcgatc
    77041 aacactaatg taaatggcgt gatgtatgct ttcaatattt ctacgatgaa tggtgttttt
    77101 ttgccatatg aaatcgcatt ttcaccgtaa ttttctcttg aacgttcgat ttgttcttct
    77161 gtcaatccat ttgctgatgc gtggaatagt tcaaataatt cttgtttcgt ttttccagca
    77221 aaagctgcat agattttttg tgtatctttc tttttttcca tctcaatctc tcctttgtgt
    77281 ccaaaagaca gctgttctcg ctgcttttgg tctttagcta ttcatcggat cgatagagaa
    77341 aaaactgaaa ggggctgaga acagatagat aatagccttg gcctttcctc tagatccttg
    77401 tttttcgaat gactgtcatc catttgttct catctccttt actaagtaat tttaattcat
    77461 gacttccaat catttttcga atagttattt tcccaattag accacctcct ttttattttt
    77521 caccgatggg gatttgcggc aacaaaaaaa cctctcgcca aatactcagc gaaaggtttg
    77581 aaaaagcata ttaaaaaaag cttctcagat ctcatcgttg agttttgaca ctgtacaacg
    77641 taaaaagcag atacctgctt ttagctacct tatgaaaagc cttatctcga caattcctgt
    77701 tctacccatt ggcgtctctc gacgtttttg ggcagtagcc tatgtttgta taggagcctc
    77761 acctaacaaa tcttattcgg ttttccttcg ttaatataac aactaaaaaa gaggatgtca
    77821 aatcaatttt ccatgttttt catacttttt ttaaaataca cacgttatat tcctgtctca
    77881 cgcggtttta tttgtctcat tttccacctc ccgctataat agaaatatag taggaaacga
    77941 ggtgctgtta tggaaagaac acttgttatt atcaagccag acggcgtgag acgccattta
    78001 gtcggaagca tcattcaacg ttttgaagca aagggactgg ccattgctga aatgaagttt
    78061 gaaactatga ctcctgaatt agcaaaagaa cattatcagc acttgactga gcgcagtttt
    78121 tttgatgaac tgatcgatta catgacttcc ggtcctgtcg tttatcttgt gctggtcggc
    78181 gaggaagtga tcgatatcgt ccgtaagatg gttggggcaa caaaagctgt cgatgctgtt
    78241 ccaggtacga tccgaggaga ctacgcgctg ccggggactg aaaacatcat tcacgcttct
    78301 gattcccgtg atgctgcggt aaaagagatc gcccgctttt tcccgccatt cgatataaac
    78361 aaaccgtctg aaaaagcggc gaagtgatac aaattctaaa ctgctggtct agttgctggg
    78421 ttcagcaatg gccagcagtt ttttctctaa ggacctccgt tgattctttc ctaacatata
    78481 ttcgagcact gtgaagaatt cttggtagtc tttcgtcttt ttttccccta aagcagcaga
    78541 aatcaatctt tgataataat ctgccatcaa tgtttcatag atcactgtac ttctttcttt
    78601 atgtgctaag ctccgtttca tatcttcatt cacactacgt gcctttttca accgaccatt
    78661 ttctatataa aacgaagtca ggttcattaa aaaagtaaag agatactgct catgattgtt
    78721 caactgtgct aatcgtcgca ttcttttttt gattttcaaa taattgttct caatgaaccg
    78781 atcactgaat atccaaggaa aatcagctag aatagatagt tcaaattgac catagtctgg
    78841 tatctgcatc aagtattctt caatgattcg gcattcataa cgtaaaaatt caaattctgt
    78901 ctcagatact tctgtttttt cgaccatgtg aagactcaaa accaaataat acagatcttc
    78961 tgttttctta aaatgcctac ggttattgct gatctcttta taaggatcaa agctgtcttc
    79021 ttgtacccga tctagcattc gtcttttttt ctttaacttt attggttcat ccagctggtt
    79081 tcgcatccat tcatattctg caagtgtcat gttcattcgc tctaaaaatg atctcaatgt
    79141 tacaaatgac atttttttca ctgaatttgt ctcaatcccg actagagaag tcttagaaca
    79201 gattccttcc gctaattggg actgtgtcaa cttcttgttg actcgaagtt tcttgatcaa
    79261 ttcaccatca tacataatag ttctcctttt taatttaaat ttttccacat tcaataaata
    79321 gatacgttaa aaaggaaaaa tacacgaaaa aaataaaaaa atgttttttt cataaaaaat
    79381 accaaccttc aagcattaga atgttgtcta actactgaag gttggtttga ttgtttattg
    79441 attatctttt tgctgttcaa cgtctgttct tgttactgga tataagttgg ttgttgtttt
    79501 attgccattt tttgaaaaga cacttgtcga atgttcgcct ttttgctttt cgatggctat
    79561 gttacgttct gcttcatttt tatagtcata ttttttcgga tcgatcgttt caaatccgtt
    79621 tggcacataa aaacgcaaga gattttcttg attcagctta tctgaaagac ttaaagcaga
    79681 tttgactttt tcctgatctt tggaaatttc ctcgtcgatt cctgctgctt tcgtatcgat
    79741 gatttctcct gtttggttat tgtaagcttt tcctcctaag atggtgtatt tgggtgtcac
    79801 gaagttccca tttcgaaaag ccactacttg atcatgctga ggagataata aatccgtacc
    79861 aaaatggaga tagtctttat catcgattcc caagagatga agtaatgtcg gcaaaacatc
    79921 gatttctcca ccgtattcgt gattgactga ccctttagta taaccaggta tatgaatcat
    79981 taatggcaca cgctgcattt gtgcgttgtc aaattcattc catgtatctg ggtcttttcc
    80041 aagagcactt gctaagtctt tattatctgt atttgagatg ccaaaatgat ccccataaat
    80101 cacaaagatc gaattttggt aaatagcgga ttttttcagg tacgtaaaaa attgttccaa
    80161 tgactgatcc aaataatgtg ccgttcgaac atagttatct actgtgctat ttccagtgtt
    80221 caaagatgga aaatcgaaat tcttatcatc cgtataataa ggcgtgtgat tggttacgga
    80281 aaggaatttc gtgtagaacg gctgttgtag atgttcaaga tattgggcag attcactgaa
    80341 taaatcttta tctaatattc cataacctag cgtttcatct gattcatcaa aataagatcg
    80401 atcaaagaaa ttgtcataac ctaagttttt atatacatga tctctattcc aaaaactagc
    80461 tacattccca tggaaaacag cgcttgtata gccttgcttt tgtccaagga tcgctggtgc
    80521 ggcttgaaag acattatctg acccaagttc tgtgaataat gagccttgag gtaaaccaaa
    80581 tgtgccagtt tccaacatat tttcagcatc acttgtcttt ccctgtccta cttcatgaaa
    80641 aaaattatca aagctgatcg ttgcttgatt ctggaaaata ctatttaaaa acggtgtgac
    80701 ttcttgtccg tctaccttca tattaatcaa aaactgctgg aaactttcta aatggagaac
    80761 gatcacattt ttccctttag cgatcccaaa tgtttcggga tttggctctg cataatgttt
    80821 ctttgtataa tctaaaactt catcaatccc attactgctt gcatgcgcgc gaacactgct
    80881 agtcattcct gttttgattc catcataaat agtatacgca tcgattccta gatatttgac
    80941 aatatatgaa cggtcaaatg ttcgctgcag caattgtgga cggttggctt cgctcagcgc
    81001 tagatttcct gaaaaaataa gccctgaaag acaggtcaca gcgatagcca tcggtttgct
    81061 gacaggttga cttttgatag gtattttctt gatcgtcaac caaaccagta tcccaatgaa
    81121 cgtagcaata tccagccagt agaggacatc atggggtttc atcaaagaaa aggagcttcc
    81181 tgataaccct tgcgacactt tcgaaaatcc caatacagat ttgactgtaa tgaaatctgt
    81241 gaattcccga taaaaaataa tgttcaagta caacaaaagc gtgtttaaaa tatcaatgat
    81301 caaaagaatg gctaatgctg gctttggctt tttaatatac aaagaaaggc caaaaaacaa
    81361 taaggtagtt gcaatcgggt tgatccacaa gataaagtac tggatcgtac cttccacacc
    81421 taacgaaaaa tctgcatagt aagcaataat cgtcttcatc cagaaaaaga aaacagctgt
    81481 caaaacgatt gctaaacgat tttggcacaa ttttttaagt tgtgtcacgt atatcacttc
    81541 tctctattca catttttcct tattttgctc ctgaaaaatg aaaattccct aaaaaagttg
    81601 ttatcttaag atttttttat tctttctaaa gattattccg tgcacttttc acagcataaa
    81661 accgctgtga tataagcgat tgaaacagta aggtgataaa agtcttgtcg cagctcctgt
    81721 ttagttgatg caggacagct ttttcacaac ttcttcttta aacggtgttc tcctgccaac
    81781 tcctcggcca caagtcacaa tatttataaa acatgagaag ctgttttttg aaattgttcc
    81841 ttgtggctca gagttaaacg gcaagctcaa gacctcttga tacacggtgt tcaatcagct
    81901 gaccttcggt attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc
    81961 tctaatactc aggtcaaaac gctgatttca caacctctgt ttttcattgt ccataggatt
    82021 gatattgtcc ttgtgatgac tcattcgtaa taattgaggc ttgattttct tcacttcccg
    82081 ttatcgtttg tccactgcca gaatctgaag gacttgttcc tgtcgactcg tttttttgag
    82141 aagagacagt tgttttcttg acttgttcat ttgtcttttt ccattccgct aaacgatcgg
    82201 cgaccacttt tttgtctact ttttcagaat aagcggtgat cacttttcca tttttcaaac
    82261 gggctacttt gtcgccatca tgagtcaaaa gcaaaacggt caaatgcttg tctttaaatt
    82321 gatattgtct gagagaaatc gcactaagta cgtcatcgat attaataaat tgattttctt
    82381 cttttccttt tggcaaatag atgtccaatt cgcctttttc gtaattggca gttattttat
    82441 actccgccca ccaataagtt gagaattctt ttttgaaatt atctactgat tctttgcttg
    82501 ctacgatttt ttctgtttct ttctgagcaa gatctgctgt catttttcct gaaaatgctg
    82561 cggataaaat aagcagtaag aaaaaaccga ataaccaaaa gagaagaaac ggtctttttt
    82621 tcctcatgct ttcctccact cctatttaat tttgactatt ctattatata caaaaaatga
    82681 aatagaaaga caaaaaagtt gaaaaagatc gtaaataatt gaacttcttt ttcacaaaat
    82741 ggtaagaatg gagaatttca cgcatttgct ctcaactatt ctttcttaag cctcaaatcc
    82801 gtttttatct gatacgtctt tgaaccagtg acccgatttt ttgattgttc tttttccatc
    82861 ttgtgctaag tctactgaaa taaagccata tcgattctta tatgcattgg tccatgacca
    82921 gttatccata catgtccaca tatgatagcc taaacaattg gcaccttctt gaattgcttg
    82981 atggacatat ttcagatgag attggacaaa ttcgatccga taatcatcgt ggatcatgcc
    83041 atcttctttg ataaatcgtg cttcgttttc tacacccata ccgttttcag aaataaagca
    83101 gtcgatattt ccataatgat ctcgtacatt gatcaaaata tcatagattc cttgttcata
    83161 gatctcccat ccgcgataag gattcatttt acgaccaggc atttcataat tgtcgaaata
    83221 atcctcaggc attggaccgt ttttagtatc gattggtgtt tcttttgctt ttacccggcg
    83281 tggctggtaa taattgatac ctaaaagatc tactgtattt tctttgatga ccgtcaaatc
    83341 ctctggatgg atcacaggca tgagatcaag ttcttttact atctcaatca attcacttgg
    83401 aaactcgcct tttacagctg gatcaaggaa tgaacgattg aagaacgcat ctgctatttg
    83461 cgctgcttta acatcttcag ggtttgattc gtctcttgga tagcttggtg tcagattcaa
    83521 gatgatacca ataacaccac cttgctccat ttcatggtaa gatttgatgg ctaacgctga
    83581 ggccaacgct tcatgatagc caacttggat cgcttttttc atatctgact cttctggata
    83641 atgccatcga tataaataac ctgcttcgac tggaacgatt ggttcattat gagtaaacca
    83701 tttttttact ttcgaaccga acaattcaaa acaacttttg gcatattttt cataggcttc
    83761 aaccgtttct cggttcaacc atccgccttt ttcttgcaga tacatcggca tatcgaaatg
    83821 atacagattc acaaagggtt cgataccgtt ttcaatcaac tcatcaaaat aacgatgata
    83881 gaaacgaacg gcttcttcgt tgattgttcc agattcatca ggtatcaagc ggctccattg
    83941 gatagatgtt cgaaatgaat tatgcccagt ctgtttcatc aactgtacat cctcttgata
    84001 cttcgtataa acttgtgaag ttttttcagg tcctacttgg tcaaagaact tttgcggttc
    84061 ttttttgtac caataatcaa aaatgttctc tccttttcca tcacctgaaa tccttccttc
    84121 tgtttgtggg ccacttgctg cagaacccca ccaaaaattt gctggaaatt gatatttttt
    84181 catcaaagca cctctttttc ttttttagtt cgttttagtt gattccatgt atgatatttt
    84241 ccatcacaat tactttttca ttttcttcct cttctttttt gattcgtttc aacagctgtt
    84301 ctgcggcttg ttccccgatt ttatctgttg gtggtgtgat cgtgattttc ggaaggatgc
    84361 tcaaatcgtt tttatccaaa taatcataat gactaaacgc aatatccttc ccgattctga
    84421 taccttcttg attgaaacat tcgatagcac cgatcgacat attataattg ctgacaaaaa
    84481 tcgctgttac tcctttttct aataattctt ttgccccata atagccactt tttctagaat
    84541 agtctcctgt aaagacctct aattggatcg atggatcatt ttgtaccgct tcttttgctc
    84601 ctgctaaacg ttctcttgct acgtagtctg tttgagtggc agcaataaat ccgatttttt
    84661 tatgtccttg ttcaccatga tgagcgatca cttttgctac actttctcga tcattcacta
    84721 atattgtatc aatacctgct ggtccttctg ggcaattcaa tgcgataact ggaatactca
    84781 tttttgtgag catttcaaat ccagaccact cttcttcgga taagaagaca atcagcccat
    84841 cgatcacatg cttcatcagg tattcaattt tttgttcaat tttttctggc tgatcggcaa
    84901 acccgcttaa taataagcta tacccatttt cttcagctac tctttcgatc cctgagacaa
    84961 cttccgaccc aaaacggctg gaaatcccgt ttatcaaaag tccaatagag aagcttcgat
    85021 tattcttcaa ccctttagca atgatgtttt ctttatagtc caacgctgaa atcgcttctg
    85081 ctattttttt catgttcttt tccttcagtt gctgaccatt caagtaacgg gaaactgttc
    85141 ccactgaaac accagccatc ttagccacgt cacggatcga tgccatacat tctcactcct
    85201 gccagttaca tttgatttct ctttcttgtt gttcgattat gatgaccgct ttctttgcat
    85261 agtgttgctt gtcatcaata tccatataac taaagtcttc agtagagcaa cttcctctca
    85321 ctattaatta tacttaaaca agtatttgaa ccggttcatt tttaatatag cattttttta
    85381 aaagattgca acactttttt aaaacgcttt cctaaaatgg cgaatttttt gcctttttaa
    85441 aattttattc taaaatttac tctatttgtg ggtgttttgt gcgtttttct cttccatccg
    85501 tttgaagttt tactttccaa tggtataatt tctttatcct atcaaatggg ggaagtattt
    85561 tgaagaaatt aatcgtacta tttattttgt ctgcgggact tttgacattg actggctgta
    85621 atttgtttgg cggctctgac caatcctcgg atgaaacaac cgattcttct gtcttaaaag
    85681 cggaaaaagc agatatcact aacagtgtat atacgctaaa agtacgtaaa gatatggatt
    85741 tatccgcggg acagttgaca tttacagata aaaaaatgga atggacacgc acgtatcaga
    85801 cacaagaaac tgattcttct gaatcatctg aagaaaaaac agtgctgaca gacatcaaga
    85861 ttactaccaa agatgacgaa tatattattt caggaaaaga aaataaaaaa gaagcaacca
    85921 tcacatttac caaaatcggt aattaccgtt tgaaggatga ggatggcaac atctacagtc
    85981 tatagtgccg tctgttggat cttcttttgt ttctcccctt cttttctgct atagtaaaga
    86041 agcaagatga ttgtaaagga gacgaaatgg atgatcgata gtcctgatta ttgtacatgt
    86101 aataacaaca aaaatatcca tacagaattt aatgaccaag gaagcttgag catatgcgac
    86161 aactgtcaca aactagtcaa agattcattt aaaacatttg aatcttatcc tgttcaaaat
    86221 tatgtaaaaa gtagaagaag ataaacaaat ccaagcaaaa ctcactatgg ctgattttta
    86281 tgaacttcaa actcagcttc ttcctttgat caagcttcat cagtaaaaca aacagtggat
    86341 catttcagtt tacaaatcaa agagtaaaga tttatttatt tcaaatattt gaatataaaa
    86401 taaccaaacg atagaaaggc ttattctaca tcacgtagta atttttcttt cccgtcgttt
    86461 ggttttttat ttttagccta attcttgacc ttttgcatgc tggttatccg taaaatattt
    86521 tccagcaggc tttccttcca attcagctag tttttcttgg atctgatgga tcaccttttt
    86581 tgcatcttct ggattttcta caaaatcgaa tttatcccca tccacttgta ttttaggaca
    86641 tacatcaaaa tcttcatacc attgattata gcgggtgttc aacgtttcat aataggtata
    86701 taacgtctca tcgctttcta gctgttcata gtcacgccca cgttttttga tacgttctag
    86761 catcgtgtcc aaagaaactt tgatatggac catcaaatca ggccgttttt ttggagcaac
    86821 atcatctaac tcgtttagca tcgtatctaa taagctatcg tactgctgta cttcgatatc
    86881 cgttacccga cctaaatcag cgtttagatg gaacaacagg ctatcttcat agatggatcg
    86941 gtctagcaca ttgtcatcgt tcactaaagc atttttcatt gctaaaaatc gcttgttcaa
    87001 aaagaagatt tgcaataaaa aagcgtactg ctcaggattt gaataaaaga gcggcaatac
    87061 ttcgttatct tcgacatttt cataaaatgg tttagaatca atctcttttg caagcatatc
    87121 cgtcaaactg ctcttacctg caccaatcgt tcctgaaatc aaaatcactg acatacaacc
    87181 cttcctcttc tataagtact cgcctacgta agtttcaaca ggcaatgttt caaaatcata
    87241 ttcacgtaca gcttggtctg attttaaata cgtatggaga ctttgtgtaa tcatcaagtt
    87301 cgtaggtacc gtctcttctt gtacaatgat catcggtttt ttcaacatag ttgccacacc
    87361 taattcgtaa gccgttcctg gatcgattgt ttgatgctca aagtcaagga tagcaacaac
    87421 aaattctgca tttgtcagtt cttccatatc tttttcgtat acttcctgcg cccatccagc
    87481 gctgaatagt tcataattgc tttcttggtg atgacgtgga gagtagaaac ttgtgactgt
    87541 tttgttttcc tccaacgctt tttcgatacg acttactcga tcgatttgct cctctgaaaa
    87601 aaatggtcct gctaaatata tttgactcat tattttgcct ccttcaataa taactgattt
    87661 ttaatagata ctgctcgtaa ttcattgacc agttccaatg gattgttgga aaagattact
    87721 tgatccaacc attttttatc cataaaatcc tcttttgcaa aagtttctaa taattgttgc
    87781 aagccgctgt aataaccgcc aatattcaat attccgattg gcttgtcggg cgtcagaccg
    87841 attgctatcc aagaaagaag ttgtgagaat tcctccaatg tacctagacc tccagggaaa
    87901 acgaggacag catctccctt ttcaaataat aatacctttc tttcatcgat cgtttctgta
    87961 ggaataaatg tagtaacatc ttttccaggc aattcagttt caaaaagccc attcggatag
    88021 atacctgtga cttttccgtt attttccagt actgttttac taatcactcc cataatcccg
    88081 gagtatgaac caccgtaaac cagttcgatt tcttcttgtg ccatgtattt tcctaacgtt
    88141 tgcgcaataa atttgtaact ttctttatta ccaaaacggg aaccgcaaaa aacagtaagt
    88201 ttcataaaaa aacactccct aactcaaaag tctatcttca ttctacacgt gtttttttaa
    88261 aataaaagac tagattttgt agttttttag tggtatatag gatagacacc actatatata
    88321 gtatttagaa aaaaacattt ttcagctatt ttatagataa aacaaaaata aataacgtgt
    88381 tttcatcgat gtgaaatgac ttacttatag aagatactgg gatttcgtcc tatatgccaa
    88441 taacgtgtat tattttaaac aacaaatact tgtttctttt attaacgaaa aaatcatttt
    88501 gttctcgtgt tatgtttcac tgataaatga tgtttctcta aataaaaaag ccgacgaact
    88561 aaacgatcaa aatttgatca tttttgttca tcagcttctc ctaaaaatct ttttgttaac
    88621 gataaatagc tggatttgta aaaatatcac ttgaatcgtc actgctggaa gaaaattcag
    88681 tgataaccgc acctgttgcg cctgcctgga actagtgttt gatattgggc tcgaacgtgt
    88741 actgatctct agcatgaaga ataatttctt tttttactgt ataataactt tctttccttt
    88801 ttggaatagt acaggaaagt ttttttgttt cctttccttc gacataaggt ataccagacc
    88861 ctttcgacaa cgaaaggttc tcatttttcc ttcatcgtca tttcaaggag ggtgccgatg
    88921 ctctggacag tttcgatcgc tcctaaacca aaatctgtat attcgattct ttctaactct
    88981 gattctttca taccattcct gcctcaaggt acatctattg tacttttttc ttgtaatcca
    89041 ttctgcctct cctaactaat tgtcaaatca tcccaagata tgtcttcttc ctctttttct
    89101 tcttggatga tttctgcatt cggatctact ggttttttca ataataaaat ggttattcct
    89161 gtgacaaaag aaccagctaa caatgcacca atgaatgccc atggtctggt catcgtagcg
    89221 actgcaaaca ttcccgatgc cggaatacgg ctatctgcgc cccaaaacat gcttaatccg
    89281 ccacctactg tcccaccgac tcccgttgct atgacattgc gtgccaagtc gttcaatacg
    89341 atagggaaac atccctctgt gatctgacag atccccatag gaaaagcggt cttcaatgta
    89401 tcgatttctt gacgattgag tatattttta cgaatgattt tccctaagaa ataagcgatc
    89461 gtcaagccga atggggttac catcgaagct aaaatcaata cagtgattgg ttcatagatt
    89521 ccttctgaaa atcgtgccac acccccttat ccagaataaa tggtaatcca gaaacagccg
    89581 tgtatctgcg gtaataagcc taaccaaacg aaaaatatga gaagctattt ttgtttggct
    89641 gttcttatta cttgatgcag ggcagctttt tcacaacctc tttttttatt tatgtttcat
    89701 aatcaatatg gtaaggatgc agctccgtat ggtagaccgc ctccgaatat tcaatcattt
    89761 ccccaatttg cgtagacgat ttccgtatcc gtttgatgcc gatctgtgcg tctgttttca
    89821 gaattccttg ttcttcttct gttaaaaata ctgccgagaa atcatcagaa aatgagtcaa
    89881 tagtatatcc ttttttcgtc agcaaacgat acaaagattc tttgccaaat tcttctctgc
    89941 tgaattgcat catttcttgt ggaagataat gaacaaaata aatataaggc tgattgttca
    90001 aataatgtaa gcgcttaaaa caaacagctt gctcaccgaa aaaggaaaac aaaggatctt
    90061 ccttctttat atggaccaat tgcaaatcca gcgtttcttt ccggacttca tatcgggagt
    90121 tctccaagat ttgcgtaaag cttgccgctt tggataatcg attgtaagga cgattgctta
    90181 gaaccgtcgt cccacgacca cttttctttg cgacatattc atctgatgcc agcagttcga
    90241 ttgcctttcg gacagtgatt ttgctgactt gaaacagttc ttctaattca ctttctgtcg
    90301 gcaacatcga accgactgga tattttcctg agaaaatatc ttctttaatt ttatctgcga
    90361 cttccaagta tagtacacgt gtccttttca taacgtcacc ctttgcttta ctattactaa
    90421 aagaatagca cataaaaaat aaaaaaagaa cacaaatcac atgtgagaag tgtgttcttt
    90481 ttcattcagc tgctttaatt acaagtttac gccatttgag gcaattactt ctttatacca
    90541 atcaaaagat tttttctttg atcgattcag tgtcccattt ccttcatcgt ctagatccac
    90601 atagataaag ccgtaacgtt tactcatttc tcctgttgat gcactgacaa gatcgataca
    90661 tccccaaggc gtatagccca tcaaatctac accgtctgct actgcattag ccatcgcttc
    90721 gatatgacga cgtaaataat cgatccgata atcatcaata atcgtgccat cctcttccat
    90781 atgatcaatg gctccaagac cgttttcaac aatgaataat ggtttctggt aacgattgta
    90841 taattcattc aatgcgattc tcagcccttc tggatcgatc tgccagcccc attcacttgc
    90901 ctcaagaaac ggatttttta ctcctcccag caagttccct tctgaagttg ctgcttgtgg
    90961 atcagtctca ttgattgccg tagacatata ataactaaat ccgatgtagt ccactggata
    91021 ttcttttagc aactggaagt ctttttccgt ttgctctaat ttttccggat cgactccata
    91081 ttttttatgg gtacgcgctg tgtatgcagg gtattctcca cgtacttgga catccgtgca
    91141 gaaaaaattg aattcttggt tttggatcat tgttgctgcc tgattgactg gattggcatc
    91201 gatgctgtaa gttgttgcat agataatcat gcagccgatt tggatatccg aacgcaattc
    91261 gtggccgatt tttacggctt tgctacttgc aacgaattga ttatgccatg cttggaaaat
    91321 attttggtac tctcctgctc cattgctttt tactaatcct tgacttaaag ctggaaagtg
    91381 aaaggccgaa ttgatttcat tgaaagtcat ccaatatttg actttactgc tgtatctctc
    91441 taatactgtc tgagcaaatc gttcatagaa gtcgatcagt tttcgatttt tccagccacc
    91501 gtattctttt gccaaatgaa gaggcatttc gtaatgagaa atcgtgatca caggttcaat
    91561 atcatatttt aagcactcat caatcagctg atcataaaat tctaatcccg cttcgttagg
    91621 agtaccttcg tctccatttg gaaaaattcg tgtccaggca atcgaaaaac gataacattt
    91681 gaatcccatt tccgcaaaca aggcaagatc ttctttgaaa cgatcgtaat gatcgattcc
    91741 tcgatgattc gggtaaatat atttttcttg atcaatcgtc cagtcaaatt cttcactgcc
    91801 gataatcgca aagcgctgct tacctccagg catagcatct gcaacggata gtccttttcc
    91861 gtctcgatca taagcccctt ctaattgatt tggcagcagt tgctccaccc cataaaaatt
    91921 tttctgaaaa acgtgattgc atcctgattt cctccttatt ttacaattgc cagaacatct
    91981 tcgtttgcaa taatctcttt ttggtctaat tcaagtatat cggcaaatgc atcagtattc
    92041 gtaatgacaa ctggagtgat tacgctatag ccagctgctc taattgcttc gatgtcaaaa
    92101 cgaatcaata aatctcctgc tttgacgaga tccccttgtt tgactaagat ctcaaagcca
    92161 ttcccattta attctactgt atccatcccg atatgaatca aaatctccgc tccgtcagtc
    92221 gttgtgatcc ctacagcatg tccagttgga aaaatagtcg tgatctctcc gtctgcaggt
    92281 gcaactagtt ctcctacttc tggatcaata gcgatacctt ttcccatcac gccagaagaa
    92341 aaaacttggt ctggtacttc actcaatggc agtactttac ccgttaaagg actttttaag
    92401 gtatgccgtg ctgaagtaat cggttctcct gcattcgcat gtttgttttc taattgattg
    92461 tcttgtgttt gttcgtcaaa tcctaaaatc aatgtaccta cgaatgcaag aacaaaagca
    92521 attcctgtag ctattactgc tactgtcaca tttgactcta caccatccac cgtattaatg
    92581 aaagtcggaa tcgtcaataa gctgaccaaa ctgctggaga aagcttttac tccggaaaat
    92641 ccgataatag ctccaccaat acctccagaa atacaagcgg caatgaatgg tttcttcaaa
    92701 ggtaatgtca caccatacac agttggttca gtgattccaa ataacgaagt cactgtagaa
    92761 gaaatcccta atgctcgaag tttcgtatct tttgttcgca atgctacagc taaagcagcc
    92821 ccaccttgtg ccaagatggc tggaagaagc attggcatca atacatcaaa cccatattgt
    92881 tcgatattca aaaacatgat cggtacgaat ccccaatgca tgccgaacat cacgaatact
    92941 tgccataaac ttcccatgat tagacctgct acgattggac taaatccata aatcgagttg
    93001 aagagaccgc ctaaagcatt accggcaacc gtcccgattg gtcctaaagc aagaaatgtt
    93061 aatggaacca tcactactaa aacgacaagc ggaactaaaa tcatttgcag aaattgcgga
    93121 atcacttttt ttacgaatgg ctctaattta ctttgaaccc atacggctag aatgattggt
    93181 atgacagaag aagtataacc agatggtgaa agaatcactg ggatcccaaa gaaactgata
    93241 gcttctcccg caccagcaac tgctgtgata gctggataca caagtgccat agcaattgct
    93301 actgctaaaa actggttggc tttgaacttt ttagctgctg taaaagcaag catgacaggt
    93361 aagaaggtaa agacaccatc tgctgcagca aacaatattt gataagtacc gctatcagct
    93421 gtcagccagc ccatcaccgt tgccaatgat aagaatcctt tcaatacccc ggcggctgcc
    93481 atcgccccta gaaaaggtgt aaatatacta gagataatat cgatcagacg attcaaaata
    93541 tttttggact cttcttttcc atcctccgaa actgcaagac cttcctcatc cacgatcgat
    93601 tgataaacat ctgctacatt actgccaatc actacttgat actgaccgcc actttgtacg
    93661 acttggatca cgtccgggtc ttcttttaac ttttgcgtat ctgctaaaga ttcatctttt
    93721 aatctgaatc gcaaccgcgt agcacaatgt actaaacttt tgacattctt ttgtcctcct
    93781 accgcttccc atacacgacg accaactgct tgattatcca ttgttttttc cttctttctt
    93841 ttttatttaa aaaataaaaa cccagattga aaaaaacagt cacaaacatt cgtgaaccta
    93901 ttttttcaat ccaggttttg cctgccatac agtaacaatc cttatgattg gatgcttttt
    93961 ttctcactta ctactctttg aatatgaatc gttaaataaa tctgctctgc gatccccatt
    94021 tcctgttttt gcgtttgtcg aagatactca ttgatccgtt cgacacaatg aaacgctttt
    94081 ggatactttc cttgaactaa tgcgtagaga aattcatctt gctcgtcaga tccttcccct
    94141 ttgagataac gctgggcaaa aaactgcaga tgagtaatga tacgctgata attcaaagat
    94201 tcttcatcga acacgatgcc gaagaattta ctgatgatac tcagtatatc tcttaccatt
    94261 gtggtagcgg tcatcgtcac ttgcatgtct tcgtttcctt gttggctatt cacaaaatga
    94321 aaggcaataa aaccggcttc atcctcagaa agttccacac ccgtcttttg tttcacgaac
    94381 aaaagagcct ctttcgctgc ttgatattct ttcggataaa atttttttgt ttcaaataat
    94441 aatggattag gcagttggat attttctttt gctcgtgtga tcgcataatg aagatgatcg
    94501 gtcaatgtca gataaatatt aggcgaaaat tcaactttta gtttatcttc agccagttcg
    94561 actacttgtt tgacccattc gatctcctct gccggaatat cagccatcag ctgctggaat
    94621 tggtttttag caaaagaatc t
//
LOCUS       DAPBBR010000002        85549 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPBBR010000002 DAPBBR010000000
VERSION     DAPBBR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 85549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.002"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..171
                     /locus_tag="RD488_000087"
     CDS             <1..171
                     /locus_tag="RD488_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7656193.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            406..642
                     /locus_tag="RD488_000088"
     CDS             406..642
                     /locus_tag="RD488_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656194.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="RD488_000089"
     CDS             649..2601
                     /locus_tag="RD488_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HDT7656195.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="RD488_000090"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="RD488_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HDT7656196.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3532..4572
                     /locus_tag="RD488_000091"
     CDS             3532..4572
                     /locus_tag="RD488_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7656197.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4670..4858
                     /locus_tag="RD488_000092"
     CDS             4670..4858
                     /locus_tag="RD488_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDT7656198.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4916..5269)
                     /locus_tag="RD488_000093"
     CDS             complement(4916..5269)
                     /locus_tag="RD488_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656199.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5800..6222
                     /locus_tag="RD488_000094"
     CDS             5800..6222
                     /locus_tag="RD488_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7656200.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6219..6449
                     /locus_tag="RD488_000095"
     CDS             6219..6449
                     /locus_tag="RD488_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656201.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6947..7147
                     /locus_tag="RD488_000096"
     CDS             6947..7147
                     /locus_tag="RD488_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7656202.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7174..8367
                     /locus_tag="RD488_000097"
     CDS             7174..8367
                     /locus_tag="RD488_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7656203.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="RD488_000098"
     CDS             complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="RD488_000098"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7656204.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10059..10982)
                     /locus_tag="RD488_000099"
     CDS             complement(10059..10982)
                     /locus_tag="RD488_000099"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDT7656205.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11178..11783
                     /locus_tag="RD488_000100"
     CDS             11178..11783
                     /locus_tag="RD488_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7656206.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12091..13107
                     /locus_tag="RD488_000101"
     CDS             12091..13107
                     /locus_tag="RD488_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7656207.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13248..14549
                     /locus_tag="RD488_000102"
     CDS             13248..14549
                     /locus_tag="RD488_000102"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDT7656208.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14595..15257
                     /gene="deoC"
                     /locus_tag="RD488_000103"
     CDS             14595..15257
                     /gene="deoC"
                     /locus_tag="RD488_000103"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDT7656209.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKERALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15278..15676
                     /locus_tag="RD488_000104"
     CDS             15278..15676
                     /locus_tag="RD488_000104"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDT7656210.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15742..16824
                     /locus_tag="RD488_000105"
     CDS             15742..16824
                     /locus_tag="RD488_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7656211.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17036..18598
                     /locus_tag="RD488_000106"
     CDS             17036..18598
                     /locus_tag="RD488_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656212.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18591..19724
                     /locus_tag="RD488_000107"
     CDS             18591..19724
                     /locus_tag="RD488_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656213.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19724..20680
                     /locus_tag="RD488_000108"
     CDS             19724..20680
                     /locus_tag="RD488_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656214.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20779..21945
                     /gene="deoB"
                     /locus_tag="RD488_000109"
     CDS             20779..21945
                     /gene="deoB"
                     /locus_tag="RD488_000109"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDT7656215.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21969..22787
                     /locus_tag="RD488_000110"
     CDS             21969..22787
                     /locus_tag="RD488_000110"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7656216.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22804..23511
                     /gene="deoD"
                     /locus_tag="RD488_000111"
     CDS             22804..23511
                     /gene="deoD"
                     /locus_tag="RD488_000111"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7656217.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="RD488_000112"
     CDS             complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="RD488_000112"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7656218.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24667..25248)
                     /locus_tag="RD488_000113"
     CDS             complement(24667..25248)
                     /locus_tag="RD488_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7656219.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="RD488_000114"
     CDS             complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="RD488_000114"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDT7656220.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26383..26796
                     /gene="rpsL"
                     /locus_tag="RD488_000115"
     CDS             26383..26796
                     /gene="rpsL"
                     /locus_tag="RD488_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDT7656221.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26880..27350
                     /gene="rpsG"
                     /locus_tag="RD488_000116"
     CDS             26880..27350
                     /gene="rpsG"
                     /locus_tag="RD488_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDT7656222.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27444..29531
                     /gene="fusA"
                     /locus_tag="RD488_000117"
     CDS             27444..29531
                     /gene="fusA"
                     /locus_tag="RD488_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7656223.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29703..30890
                     /gene="tuf"
                     /locus_tag="RD488_000118"
     CDS             29703..30890
                     /gene="tuf"
                     /locus_tag="RD488_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7656224.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31297..31605
                     /gene="rpsJ"
                     /locus_tag="RD488_000119"
     CDS             31297..31605
                     /gene="rpsJ"
                     /locus_tag="RD488_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDT7656225.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31636..32265
                     /gene="rplC"
                     /locus_tag="RD488_000120"
     CDS             31636..32265
                     /gene="rplC"
                     /locus_tag="RD488_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDT7656226.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32293..32916
                     /gene="rplD"
                     /locus_tag="RD488_000121"
     CDS             32293..32916
                     /gene="rplD"
                     /locus_tag="RD488_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDT7656227.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32916..33206
                     /gene="rplW"
                     /locus_tag="RD488_000122"
     CDS             32916..33206
                     /gene="rplW"
                     /locus_tag="RD488_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDT7656228.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33245..34078
                     /gene="rplB"
                     /locus_tag="RD488_000123"
     CDS             33245..34078
                     /gene="rplB"
                     /locus_tag="RD488_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDT7656229.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            34121..34399
                     /gene="rpsS"
                     /locus_tag="RD488_000124"
     CDS             34121..34399
                     /gene="rpsS"
                     /locus_tag="RD488_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDT7656230.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34422..34769
                     /gene="rplV"
                     /locus_tag="RD488_000125"
     CDS             34422..34769
                     /gene="rplV"
                     /locus_tag="RD488_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDT7656231.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34783..35439
                     /gene="rpsC"
                     /locus_tag="RD488_000126"
     CDS             34783..35439
                     /gene="rpsC"
                     /locus_tag="RD488_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDT7656232.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35442..35876
                     /gene="rplP"
                     /locus_tag="RD488_000127"
     CDS             35442..35876
                     /gene="rplP"
                     /locus_tag="RD488_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDT7656233.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35866..36054
                     /gene="rpmC"
                     /locus_tag="RD488_000128"
     CDS             35866..36054
                     /gene="rpmC"
                     /locus_tag="RD488_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDT7656234.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            36079..36345
                     /gene="rpsQ"
                     /locus_tag="RD488_000129"
     CDS             36079..36345
                     /gene="rpsQ"
                     /locus_tag="RD488_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDT7656235.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36403..36771
                     /gene="rplN"
                     /locus_tag="RD488_000130"
     CDS             36403..36771
                     /gene="rplN"
                     /locus_tag="RD488_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDT7656236.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36808..37116
                     /gene="rplX"
                     /locus_tag="RD488_000131"
     CDS             36808..37116
                     /gene="rplX"
                     /locus_tag="RD488_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDT7656237.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            37144..37683
                     /gene="rplE"
                     /locus_tag="RD488_000132"
     CDS             37144..37683
                     /gene="rplE"
                     /locus_tag="RD488_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDT7656238.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37702..37887
                     /locus_tag="RD488_000133"
     CDS             37702..37887
                     /locus_tag="RD488_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDT7656239.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37923..38321
                     /gene="rpsH"
                     /locus_tag="RD488_000134"
     CDS             37923..38321
                     /gene="rpsH"
                     /locus_tag="RD488_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDT7656240.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38353..38889
                     /gene="rplF"
                     /locus_tag="RD488_000135"
     CDS             38353..38889
                     /gene="rplF"
                     /locus_tag="RD488_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDT7656241.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            39050..39406
                     /gene="rplR"
                     /locus_tag="RD488_000136"
     CDS             39050..39406
                     /gene="rplR"
                     /locus_tag="RD488_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDT7656242.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39427..39927
                     /gene="rpsE"
                     /locus_tag="RD488_000137"
     CDS             39427..39927
                     /gene="rpsE"
                     /locus_tag="RD488_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDT7656243.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39942..40121
                     /gene="rpmD"
                     /locus_tag="RD488_000138"
     CDS             39942..40121
                     /gene="rpmD"
                     /locus_tag="RD488_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDT7656244.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            40165..40605
                     /gene="rplO"
                     /locus_tag="RD488_000139"
     CDS             40165..40605
                     /gene="rplO"
                     /locus_tag="RD488_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDT7656245.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40605..41900
                     /gene="secY"
                     /locus_tag="RD488_000140"
     CDS             40605..41900
                     /gene="secY"
                     /locus_tag="RD488_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDT7656246.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41962..42609
                     /locus_tag="RD488_000141"
     CDS             41962..42609
                     /locus_tag="RD488_000141"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDT7656247.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42800..43018
                     /gene="infA"
                     /locus_tag="RD488_000142"
     CDS             42800..43018
                     /gene="infA"
                     /locus_tag="RD488_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDT7656248.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            43051..43167
                     /gene="rpmJ"
                     /locus_tag="RD488_000143"
     CDS             43051..43167
                     /gene="rpmJ"
                     /locus_tag="RD488_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDT7656249.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            43185..43550
                     /gene="rpsM"
                     /locus_tag="RD488_000144"
     CDS             43185..43550
                     /gene="rpsM"
                     /locus_tag="RD488_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDT7656250.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43578..43967
                     /gene="rpsK"
                     /locus_tag="RD488_000145"
     CDS             43578..43967
                     /gene="rpsK"
                     /locus_tag="RD488_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDT7656251.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            44047..44985
                     /locus_tag="RD488_000146"
     CDS             44047..44985
                     /locus_tag="RD488_000146"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDT7656252.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            45013..45393
                     /gene="rplQ"
                     /locus_tag="RD488_000147"
     CDS             45013..45393
                     /gene="rplQ"
                     /locus_tag="RD488_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDT7656253.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45665..46504
                     /locus_tag="RD488_000148"
     CDS             45665..46504
                     /locus_tag="RD488_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7656254.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46480..47349
                     /locus_tag="RD488_000149"
     CDS             46480..47349
                     /locus_tag="RD488_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7656255.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47339..48136
                     /locus_tag="RD488_000150"
     CDS             47339..48136
                     /locus_tag="RD488_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7656256.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48339..49085
                     /gene="truA"
                     /locus_tag="RD488_000151"
     CDS             48339..49085
                     /gene="truA"
                     /locus_tag="RD488_000151"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7656257.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49418..52087)
                     /locus_tag="RD488_000152"
     CDS             complement(49418..52087)
                     /locus_tag="RD488_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HDT7656258.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52325..52513)
                     /locus_tag="RD488_000153"
     CDS             complement(52325..52513)
                     /locus_tag="RD488_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDT7656259.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52783..53145
                     /locus_tag="RD488_000154"
     CDS             52783..53145
                     /locus_tag="RD488_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7656260.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            53197..54879
                     /locus_tag="RD488_000155"
     CDS             53197..54879
                     /locus_tag="RD488_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDT7656261.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54996..57032
                     /gene="recG"
                     /locus_tag="RD488_000156"
     CDS             54996..57032
                     /gene="recG"
                     /locus_tag="RD488_000156"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDT7656262.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            57081..58082
                     /gene="plsX"
                     /locus_tag="RD488_000157"
     CDS             57081..58082
                     /gene="plsX"
                     /locus_tag="RD488_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDT7656263.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            58204..58446
                     /gene="acpP"
                     /locus_tag="RD488_000158"
     CDS             58204..58446
                     /gene="acpP"
                     /locus_tag="RD488_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7656264.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58714..59718
                     /locus_tag="RD488_000159"
     CDS             58714..59718
                     /locus_tag="RD488_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656265.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59719..60663
                     /locus_tag="RD488_000160"
     CDS             59719..60663
                     /locus_tag="RD488_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656266.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60663..61625
                     /locus_tag="RD488_000161"
     CDS             60663..61625
                     /locus_tag="RD488_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656267.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61652..62566
                     /locus_tag="RD488_000162"
     CDS             61652..62566
                     /locus_tag="RD488_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656268.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62592..64373
                     /locus_tag="RD488_000163"
     CDS             62592..64373
                     /locus_tag="RD488_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7656269.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64721..65407
                     /locus_tag="RD488_000164"
     CDS             64721..65407
                     /locus_tag="RD488_000164"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDT7656270.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65427..69008
                     /gene="smc"
                     /locus_tag="RD488_000165"
     CDS             65427..69008
                     /gene="smc"
                     /locus_tag="RD488_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDT7656271.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            69017..69826
                     /locus_tag="RD488_000166"
     CDS             69017..69826
                     /locus_tag="RD488_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7656272.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69837..70835
                     /gene="ftsY"
                     /locus_tag="RD488_000167"
     CDS             69837..70835
                     /gene="ftsY"
                     /locus_tag="RD488_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDT7656273.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            71022..73289
                     /gene="gshAB"
                     /locus_tag="RD488_000168"
     CDS             71022..73289
                     /gene="gshAB"
                     /locus_tag="RD488_000168"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HDT7656274.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(73378..73830)
                     /locus_tag="RD488_000169"
     CDS             complement(73378..73830)
                     /locus_tag="RD488_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HDT7656275.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            73980..74930
                     /locus_tag="RD488_000170"
     CDS             73980..74930
                     /locus_tag="RD488_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7656276.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            74923..75882
                     /locus_tag="RD488_000171"
     CDS             74923..75882
                     /locus_tag="RD488_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7656277.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            75879..76634
                     /locus_tag="RD488_000172"
     CDS             75879..76634
                     /locus_tag="RD488_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656278.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            76657..77610
                     /locus_tag="RD488_000173"
     CDS             76657..77610
                     /locus_tag="RD488_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7656279.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(78254..78550)
                     /locus_tag="RD488_000174"
     CDS             complement(78254..78550)
                     /locus_tag="RD488_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HDT7656280.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            78905..79261
                     /locus_tag="RD488_000175"
     CDS             78905..79261
                     /locus_tag="RD488_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7656281.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            79271..80170
                     /locus_tag="RD488_000176"
     CDS             79271..80170
                     /locus_tag="RD488_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDT7656282.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            80687..81418
                     /locus_tag="RD488_000177"
     CDS             80687..81418
                     /locus_tag="RD488_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7656283.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            81563..83590
                     /locus_tag="RD488_000178"
     CDS             81563..83590
                     /locus_tag="RD488_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDT7656284.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            83698..84795
                     /locus_tag="RD488_000179"
     CDS             83698..84795
                     /locus_tag="RD488_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7656285.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            85102..>85549
                     /locus_tag="RD488_000180"
     CDS             85102..>85549
                     /locus_tag="RD488_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656286.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        28139 a        15266 c        18129 g        24015 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tctataagtt atattatcat aataccacaa
     3301 aatcacaaat tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt
     3361 aatttggtat gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt
     3421 tgtactccaa aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat
     3481 ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact
     3541 tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg
     3601 caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga
     3661 aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa
     3721 cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga
     3781 tattacgtgg attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg
     3841 gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct
     3901 acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg
     3961 ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt
     4021 ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca
     4081 gttatggaag ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacggat
     4141 tgtaaaatct gttttaagta cggtttatac tatagccctg ttagtactcc agcagatttt
     4201 cggatgctta ctcctattgt actggagcaa gcctttagaa aagctggaac agaattgtta
     4261 gagccatatc ttagttttaa agtttatgca ccacaggaat atctttcacg ggcatataac
     4321 gatgctccca aatattgtgc aaatatcgta aatactcaac tgaaaaataa tgaggtcatt
     4381 attattggag aaattcctgc tcgatgtatt caagattatc gcaatgattt aacttttttt
     4441 acaaatgggc ttagtgtttg tttagcagag ctaaaaggat atcaggttac cactggcgaa
     4501 cctgtttgcc agacccgtcg tctaaatagt cggatagata aagtaagata tatgttcaat
     4561 aaaataactt agtgcgtttt atgttgttat ataaatatgg tttcttatta aataagatga
     4621 aatattcttt aatatagatt tgaattaaag tggaaaggag gagattgtta ttataaacta
     4681 caagtggata ttgtgtccta tttgtggaaa taaaacaaga ctacgaatac gagtggatac
     4741 tatacttaaa aatttccctt tatactgccc caaatgtaag aacgaaactt taattaatgt
     4801 tcaaaaaatg aatataataa caatcaaaga gccagacgcc aagacgcaga gccgataatt
     4861 tgagaaatga aactctcatc ttatcggctc tttttgttta tctgaatttt actgactagc
     4921 cttcaatatt tcttgcttca ttgatacctt ttgctagtgc ttccattaag gatagttctt
     4981 tgtctgtaaa gctatccatg tatttttcta cctgtaacct tcgagtgctt ttaatcaaat
     5041 tatctgtagg taagaaaaat tcatcaatag atacatggag taatgataca agatcataca
     5101 gcacttgtgt acttgggtgt tgtcctttgt tttctatatt tgttaaataa cgtgggtcaa
     5161 tttcaatcat tgttcccact tgttcacgag tgagaccccg tttcattcga gcctctttaa
     5221 tcgctaaacc aacggctcta aaatcgtatt tatcttcttt tttacgcata ctaaatcacc
     5281 tctatacatt ttactgttcc tatataacca taaacaggta tagaaaaaca tgttatatag
     5341 tttatgagtt cctatagaac actgtggaat ttattaatgc gatgaatcca atttcaaata
     5401 gaaaggtcgc tgattttatt tacctataca actttataaa atttagtcat actcctagaa
     5461 agtagataaa attggcgact taatggaggg aaaagtcgcc atgagaaaga taatctgtca
     5521 tctagttctc ttaattaagt tcttatcaaa aaaacttatc cacctgtact ggatagatat
     5581 gaccatcaat gtggttttgc agattacata gatagaaaaa tcaaagcata tgaacagaga
     5641 aaacaatctg tttatgtgct tttttggtca cttaataaat atcttttagg atttctcttc
     5701 atttatgcaa caaatccccc gttcgtgtcg gggtttagta tgaagggaga taaagaagca
     5761 catgccactc cctttcacga cagaaagggg gtgaaaagca tgaaaccatc ttcttttcaa
     5821 gaaaccatag aaaatcagtt tgactatatc tgcaaacaag ttattgaaga tgaacgaaaa
     5881 gattacttca aacatctaga cagactatca gcaaaagaag tctcgttttc tgatatagat
     5941 aactaccttg tcaactcttt ttctactgtt gatacgtacg tcactgattt ccaactattt
     6001 aaattatttg gattaagaat caatgttgaa agtgatttat taagtgaagc cctgcgtcat
     6061 ctttcagaga aaaaacggaa cattatttta cttcattact ttatggatat gagtgatgtg
     6121 gagattgcgg agttactaaa tttgaatcgt tcgactgttt atcgtcatcg aataagtgga
     6181 ctagccatga ttaaagaatt catgaaggag tgtaaagaat gaaaacagct tatccaaggg
     6241 ttcccttccc cctcattgta aaggcgacag atggcgacgt ggaagcaatt aatcagattg
     6301 ttaaacatta tcgagggtat acctcaaaac gttcattacg tcgcatgaca gacgaatatg
     6361 gaaattctca tatggttatt gatgaaaccc tacgtggcag aatggaaacg aaactcatct
     6421 ctaagatttt atcgttcgaa attaaatagt cccatttttt cgtggaagcg tgtcgaatcg
     6481 tatccacgct tcccgatttg ggaggtttgt tattccatca aagcatattg tgtgttcagt
     6541 aggttttgat aggctaacaa gccaaacgtt ctttgacaac caaataaagg caatcgaata
     6601 cgtttcggta agaaaagagc tgatgaacta acacgccatg acctacaaaa ttagtgagcg
     6661 attcatgtta gtaattcgaa agtaatcttt agcaggattg ctgccatgac tttcttatcg
     6721 tgataatgat actcccgtat agccatagtc cgagcgttag aagcgtcaca ggcaatgggt
     6781 acggctacat gagaaccatg cagaagtgaa attcctgtga gctttgctag agctgttcga
     6841 ttgctaagat attcttctct tgtcagtgta ttattataaa actatttgat ataattatag
     6901 gtgaatattg gagttttcct agcctataat tgggaaagga gtaataatga taacggtcac
     6961 aaaaaaggat ttagttgagc taggatatgg aacttctttt tcagcagaca tcataaaaaa
     7021 agcaaaagaa ttgatgatta caaaagggca tatctactat caatctcgaa agctagatag
     7081 agtccctcgt gaagctgttg aagaaattct aggaattcgg ttttcaaatg aaaacaggtc
     7141 tgagtagttt ttgcacagta aggagtaaaa actatggtta aagacccaat aaaaaaagca
     7201 aagaatggaa cctattattt tcgtgcaaat ctaggttatg attctaaagg gaaaaaaatt
     7261 caaaaatatc gtagtggatt cactactaaa aaagaagcaa gagaagaata ttcgaaactg
     7321 ctattgatga aaccagaaga attaagtgag aataaggata aaatgacgtt taaacattat
     7381 atctttgaaa ttttccttcc atggtataag acacaggtaa agctcagaac atatgaaaat
     7441 cgcttaccaa ctattaagaa gcatttctct tattttgata aaatggctgt ttccgatatt
     7501 gagcctattg atgtgcaaaa ttggcaacta aaattatcaa agaagtgtaa gtcttcttat
     7561 gtaagagctg ttcaaggact attttcagtt gctatggatc gagcaattgt ccttgggata
     7621 accaccacaa atccatctaa gattattggc aatgtgaaaa agcaaaagtc taaaattgaa
     7681 ttttggacaa aagaagaatt tgaaaaagta atctctctaa tttacaaaga agattactat
     7741 caacactttt tatttatctc tctgtggttt ttatttatga ctggaatgcg aattggtgaa
     7801 gctactgcca ttcaatggga agatattgat tttgactcag gagtactaac catcaacaaa
     7861 acactctatt acaagaatca atcgaattat agatttgttg aaccaaaaac aaaggcgagc
     7921 gttcgtcata ttgtattaga taaatgcaca ttaacttatt tatccgaatg gaaggaagta
     7981 caacaaaatc taattcagac agactttgta atgagctata acggtattcc tacccaaaaa
     8041 catacactat catatgctat tgaacgctat gctaagctgg ctggtatcca tcgaatcaga
     8101 atccatgggt tacggcattc tcatgcttcc ttgttaatca gtatgggaga aaatccactt
     8161 atcattaaag atcgtctagg acacgaagat attgagacga ctttaggaac gtatggacat
     8221 ctttatccta acagtaattt cgaggtagct aacaaattaa atggagccat ttcctttaaa
     8281 gaagcaaaac aaaattatga tacttcacca aagaatcaat ttactgtaga ctacttgcga
     8341 aacaaagaaa tgaaaaaagt gcaataaaag tgcagtaaaa agataagaag agccagaaac
     8401 ccttggtata agaggatttc tagctctcct acaactattc ccactccact gttgctggtg
     8461 gtttagaagt gatgtcatac acgatacggt tgacgtgggc tacttcgttt acgatacgta
     8521 cagagatttt ttgcaagact tcccatggga tacgggcaaa gtcagcggtc attccgtcga
     8581 ttgaagttac agcacggata ccgactgtgt agtcgtaagt acgtccgtca cccataacac
     8641 cgacagagcg gatccctgga agaacagtga aatattgcca gatatcacgg tcaagtccag
     8701 cagctgcgat ttcttcacgc aagatagcat cagattcgcg tacgatttct agcttgtctt
     8761 cagtgatttc gccaagaaca cgaataccaa gaccaggacc agggaatggc tgacgccaaa
     8821 cgattgaatc aggcatgcct aactgagtcc ctaattcacg gacttcgtct ttgaataatg
     8881 tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg cagtccacct acattatggt
     8941 gagatttgat cgtctgtgct gtttctgtac cagattcgat aacgtcagta tacaacgttc
     9001 cttgtgctag gaaagagacg ccttcttcac cagcaagttt tgttgcttcg tcatcaaaaa
     9061 catatacgaa ttcattccca atgattttac gtttttgttc tgggtcagat acacctttca
     9121 acttgtctaa gaagcgatct cttgcatcga ctttgatgat gttcaagccg aattttccgc
     9181 ctagactttc cattacttgt tccgcttcgc ctttgcgtag cagaccgtgg tcaacaaaga
     9241 tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac cccaacgaca ctagaatcaa
     9301 cgccacctga aagaccaagc aagacttttt tgtcaccaac ttgttcacgg attttttcta
     9361 cttgcatatc gataaagtta tccattgtcc agttaccttc acagtgacaa acatcaaagg
     9421 caaagtggcg cagcaattcg attccgtatt cggaatgacg tacttctgca tggaattgga
     9481 taccataaaa attacgtgtt gtgtcttgga tagaagcaat cggacaatct ttgcttgttc
     9541 cgactgtttc aaagccttca ggaactttag ttaccaagtc accatggctc atccatactg
     9601 tttgttgttt tggtgtttct ttaaacaaga cagcttgatc gcttgttact tctaacaagg
     9661 ctttcccata ttcgcggttt ttagcaggct ctacggaacc gccaagtttg tacgtgatca
     9721 attgcatacc atagcaaatc cctaatacag gaatacctaa attgaagatc tcaggatcga
     9781 tcccaaatgc attctcatca tatacactgt ttggtccgcc agaaagaatg attccctttg
     9841 gattcatcgc ttttacttct tctgcagtaa tgcggtggct caataattcg gaaaagactc
     9901 caagatcacg aatacgtctt gtgatcaatt ggttatactg actaccgtag tctaatacga
     9961 taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa atttattacc cctatccctt
    10021 taaattttat ctcaaaatag tcaaactatt ttaaaatgct aatattttcg catgaaaatc
    10081 gaatcgatga tatgattttc agttttatgg agaattatat cggctcttcc tcgtgtaggc
    10141 aagatatatt cctgtaaatt tttcaaattc acatttttcc atacatcttt tgccatttta
    10201 aaggcttctt cacgatctcc gatagcaaaa cgataataat aattctctgg attttggaaa
    10261 gccgtatcca gtaacgcacc aaaacgatcc aaataccatt tttcgatcag cacgggatcg
    10321 gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt agatttgctg attcgcaggt
    10381 aattgaagcg tattgatccc ctcaacgatc aagatatcag gctgctggat caattcgtac
    10441 ttgtctggaa tgatatcata cacatcatgt gagtaaacag gtacttttat ctcttcctga
    10501 ccagatttta cacggttcaa gaaatcgatc agcatctcca tatcataact ttcaggaaat
    10561 cctttacggt ccatgattcc acgctctttt aatatacgat ttggataaag aaatccgtca
    10621 gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag acaaaatcgt ctgcagcagt
    10681 ctggctgttg tactttttcc aacggctaca cttccggcga tcccgataat aaaaggcggt
    10741 acttctacgt atttatgaag aaataaacct ttactcaaga acaaagattc aaattctttc
    10801 atataaagat aaatcagatg agcaagaggt acatagatat ctcgaacatc ctgcatggaa
    10861 atgcggtcat tcaaactttt gatattatct agttcatctt gtgtcaaagg tgcttgccca
    10921 ttacgataaa attctcgcca ttcttctctt gccacacggt agtagttcat tggatcattc
    10981 atattagcct cctgcgttct cccatcaatg gaactatttt aacacaaaat aaacgcaaac
    11041 cccaccactt aagagagatt gccgatcttt ttgtataatc tttataatag aaagaaacgg
    11101 agtcttattc ttgacttgcg cacggataca taaaaggata gactgttgtc atgaaagaaa
    11161 tgagaaggat ggaagacatg acaaatcatt actattctga acgcccagat acggcgcacg
    11221 attttgaaca atgggctttt gagttaaaag gcagaacctt tcaatttgta acagattctg
    11281 gtgtattttc acgtgaaaca gtggattatg gttcacgtgt cctgattgat gctttcgatt
    11341 gggaagagtt acctgatgaa ggaaagatct tagatgtggg atgcgggtat ggaccgattg
    11401 ggttagcttt ggcatttgcg acacagcggt ttgttgaaat ggtcgacatt aatgaacgag
    11461 cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat cgaacatgtt gatatccatc
    11521 aatcgaatat ctatgaagca gttcatgaag aaacctatgc agctatcgta agcaatccgc
    11581 cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac aggcgcatat cctcggttga
    11641 agaagggcgg tacactgaca attgtgatcc agaagaaaca aggagcgccg agtgcgcaaa
    11701 agaaaatgga agaaacattt ggtaatgcag aaatcgtcac aaaagataaa ggatattata
    11761 tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg gagcgacgaa agagtggaac
    11821 tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt tgagaagttt ttaaaaacaa
    11881 agaactattt tttcttcaaa aagaaatagt aggaacagag tcgttgtttt ttacgataaa
    11941 ataaataaga tacagaactt gtatagaagg ctgccaagtc ggtagataaa ggaggttttt
    12001 atcaaaaaac atactttcct tttttctcta ttcttttctt gggggttttg gtacactgat
    12061 agggaattta gatagaaggg agccaatagg atgaagctga ccatcagaga tatcgcagaa
    12121 atggcaggcg tatcagtaac aactgtctca cagattttga ataacaaagg aagcagattt
    12181 agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg aacatcatta taagcccgat
    12241 tatttcgctt caaatgtgat caatcgacat tcaaagacca tcggaatgat cgtccctgat
    12301 gtcactgatt tcttcttctc caaactgatc gaaggtgtag agagctattt gaatcctttg
    12361 ggctatgtga tcatgttatg caattctcgt catagccaag aaaatgagat caagtattta
    12421 caagagcttt cccaccgctc agtggacgga atcttgctgg ccacaccaaa tattttacct
    12481 gagaaatatg cattagacag cggtttttat caaaaaatgc caatcatttt aatcgatcgc
    12541 ggattgaatc gtcgggataa cggacggctt atcgtaaagg aatatgaggg cgcctatcaa
    12601 gctgtttcgc tgtttattga aaatggccat acgaagatcg gcatgctgaa ggaaaccact
    12661 ggatactatc aattagaaga acgtttcaac ggatatcgtc atgcgctgaa agatcatggc
    12721 ctgcctttta atgggaaatt tgttgaacat ggagagttga ctgtccaagg tggatatact
    12781 gcatcaaaaa aattactcaa acataaagat atcacggcta ttttttgcgg gaatgatgcc
    12841 atggcgatcg gatgctatca ggcgatcgat gaattgggca aaaaaatccc agaagatatc
    12901 tcagtcatag gattcgatgg attaaagctg tcagaataca tgattccgca attgacgaca
    12961 gtgcagcagc caagttttga tattggattt tatgctgcac gtttcctgat cgatacgatc
    13021 gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa caaaattaat tattcgtgag
    13081 agcgtaaaag tattgacaaa gggctaactc ggcggtatat tgcttatgta agcatttaca
    13141 aaggctagtt agtgcttttt ttatttttag taaaccagtt tactaaagtg gtttaccttt
    13201 cctaaaaata atgtataata ccgaatgaag acaaggagga tcaggcaatg cgaatggtgg
    13261 atctgattga aaaaaagagg gatggaaacg agctgtcgaa agaggaaatc gagtacatcg
    13321 tcacgaacta tacgaatgga aagattccag attatcaagt cagtgcatta ttgatggcaa
    13381 ttttttatca agacatgaca aatgaagaaa tcacgaactt aacattggcg attgctaatt
    13441 ctggtgatgt catcgatttg agttctcttg aaggaataaa ggtagataag cattcgacag
    13501 gtggcgttgg tgacacgacc acattgattt tagcccccct agtagctagt gtcggagtga
    13561 cagtggctaa aatgtctgga cgcggtctag gttacacagg tggtacacta gacaagctag
    13621 aagcaattcc cggatttcag atcgagcttt cggatgaaga atttgtacgc attgttaatg
    13681 aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc accggcggac aaaaaattgt
    13741 atgccttgcg tgacgtcaca gcgaccgttg attctcttcc gctgattgcc agttcgatta
    13801 tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt ggatgtgacc actggagacg
    13861 gtgctttcat gaagaacatc gaagatgcaa gacgtctggc aaagaccatg acgagcattg
    13921 ggaaactggc taaccgagaa acagtggcgg ttatctcaga tatgtcagaa cctcttggcg
    13981 aagctatcgg aaatagtcta gaagttgtcg aggcaatcga aacattacaa ggaaatggtc
    14041 cagaagatct agtagaaatg tgctacgcct taggaagcca aatggttgtt cttgctggca
    14101 aagctaagac aaccgatgaa gcaagaacgt tgcttcaaga agctctggaa tcaggtaaag
    14161 cgttagcaaa attcaaagaa atgatccaaa atcaaggggg agacccagcg atcgtggaac
    14221 atccagaacg aattttgact gcacgctaca caatggagct tcctgctaaa caaagcggag
    14281 ttgtgtcaaa aatcgtggca aatgaattag gaattgctgc aatgatgcta ggtgctgggc
    14341 gtaaaaccaa agaagaagat attgatcacg ctgttggatt gaaactgcat aaaaaaattg
    14401 gtgacactgt gacaaaaggt gagtcactat tgacgatcta tagtaacgac gaagaaatca
    14461 cttctgtcat tgaattatta tataaaaata ttgaaattgg tgaatcggca atgaagccaa
    14521 cgttgattca tgacatcatc acagaataaa ggaaaaaagc ggactttacc gttttaaaga
    14581 aaaggggaaa agaaatggaa ctaaaccgaa tgatcgacca tactattttg aaagcagacg
    14641 catctaaaga agctgtgatg caaattatcg aagaagcaaa aaaataccat ttttattctg
    14701 tctgcatcaa tccagcatgg gttgcgctag cgaaagaaca attacaaggt gagccagtag
    14761 ccgtatgtac agtaatcggg tttcctctag gagcaaacac acccgagaca aaagcatttg
    14821 aaacaacaga tgccatcaat aacggtgcag atgaagtcga tatggtcatc aatatcggtg
    14881 ctttgaaatc aaaggatgat caacaagtcc aaaaagatat cgaagcagtt gttgaagcag
    14941 caaaagagcg tgcgcttgtc aaagttatta ttgaaacatc gttattagat agagaagaaa
    15001 tcatccgagc ttgcgaaata gcaaaagctg caggcgctga ttttgtcaaa acatcaactg
    15061 gtttctcaac aggcggagca aaggtagagg atgtccgttt gatgcgtgaa actgtaggac
    15121 cagaaatggg tgtcaaagct tccggcggta tccataacga agaagaagca atggcaatga
    15181 tcgaagctgg tgctacaaga atcggaacaa gcgcaggagt agcaatcgta tctggttcaa
    15241 ctggtgaagg ctattaattt tttcaaagga gaagctcatg gcagaactca aacaagaatg
    15301 gatcaacaca gctattgaag cgttagataa agcctatgtt ccttattccc attttccggt
    15361 aggcgcttgt ctcgtaacgg aatcaggcaa gatttatcaa ggcatcaaca ttgagaatgc
    15421 atcatttgga ttaacgaatt gtgccgagcg cacagctttt ttcaaagcag tatctgaagg
    15481 agaaaaaaca tttacgcatc tagtcgtagc ggggcacacc cccgatccta tctctccttg
    15541 tggtgcatgt cgacaagtaa tggcagaatt ctgttcccct gatatgccgg ttacgctagt
    15601 aggagacaat ggtgtgacga aggcaacgac cgttcgtgca ctgctgcctt atgcatttac
    15661 tgaaaaagat ctataactca tgttcattca gtcagctgac tgttgaaaaa taaaacaatt
    15721 attttaggag gctttacaga aatgaaaaaa gcaaaattat ttggtttagg tgctgtcgca
    15781 ctagcagcag ggttattttt aggtgcatgc ggcaacaacg gctctactga ttcatccggt
    15841 ggcaaaagct catcagacac aacaactgca gcattgatca cagacacagg tggtgtagac
    15901 gaccgttcat tcaaccagtc agcttgggaa ggactagaaa aatgggggaa agatcaagga
    15961 ctttcacgag gaaatgatgg cttccaatat ttccaatctt caaatgaatc agattacatc
    16021 ccaaatattg accaagcatt gaatgctgga ttcaaaacga tttttggtat tggttataaa
    16081 ctaaaaccag cgatccaaga acaagcaaca aacaatacag gtacgaactt tgttattatc
    16141 gatgatgtca tcgatggatt agataacgtt gtatctgcaa ctttcaaaga caacgaagct
    16201 tcttatcttg caggtgttgc agcagcttat acgactgaaa caaacgtagt cggctttatc
    16261 ggcggtgtaa aaggtgaagt aatcgatcgt tttgatgctg gattcaaagc cggtgttgat
    16321 gcaggtgcga aagaattagg aaaagaaatc aaagtattga atcaatatgc tggtgacttc
    16381 tctgctccag ataaaggacg ttcaattgct caaggtatgt atgcacaaaa cgcagatatc
    16441 atcttccatg cttcaggcgg tacaggtaac ggtgtattcc aagaagcaaa atcattgaac
    16501 gaatcaggcg acaaaaaagt ttgggttatc ggtgttgacc gcgaccaatc agacgaaggc
    16561 gaatacacat taaacggcga aaagaaaaac ttcacattga catctacact gaaagcagtt
    16621 ggaacagtag tagaagattt ggcacaaaaa tcagcggacg gtaaattccc tggcggcgaa
    16681 cacactgttt atggattgaa agaagacggt gttggtctaa cagaaggaca actttctgac
    16741 gaagcgaaaa aagcagttga tgaagcaaaa gaaaaaatca tttcaggtga cgtaaaagtt
    16801 ccagaaactc ctgaagaaaa ctaaaaccat ttctatagcc ttgttagaca catgtttgac
    16861 aaggctatgg tttgattaga acaagaattg ttcatttatc caagctgcct tgtgacagtt
    16921 tggataaggg aacaactccc tgaagtaatg tttgtttcaa aagaagaacg ctcactaagc
    16981 gtgaatctta gtcaatcgtt gccctagata gaaatcgtta ggatgtgaaa aaaaggtggt
    17041 tcaagaaaat attgtcatag aaatgcagaa tattaccaaa gaatttggaa cattcaaggc
    17101 aaatgacaac atcaatttac aagtaaaggc aggagaaatt catgcgttgc ttggagaaaa
    17161 cggtgctggc aaatctacat tgatgaacgt gctttccgga ttattagagc cgacatcagg
    17221 gaaaattttg atgcgtggga aagaagtaaa gatcacaagt ccgaccaaag ccaaccaatt
    17281 agggattggg atggtccatc agcactttat gcttgttgat gcctttactg taacagaaaa
    17341 catcgtgttg ggaagcgagc ctagtcgcgc agggatgctt gaccataaaa aagcacgaaa
    17401 agagatccaa aaagtttctg aacagtatgg attgtcagtc aacccagatg cttacgttcg
    17461 tgatatttca gttggaatgg aacaacgggt agaaatttta aaaacacttt accgaggagc
    17521 agatgtactg atttttgatg agccgacagc tgtattgacc cctcaagaaa ttgatgaatt
    17581 aatcgtgatc atgaaggaat tagtcaaaga aggcaagtcg atcattttga ttacgcataa
    17641 gttagatgaa atcaaagcag tagctgaccg ctgtacagtt atccgccgtg gaaaaggaat
    17701 cggtacagtc aacgttaaag acgtaacctc acaacaatta gccgatatga tggttggaag
    17761 aacggtttca ttcaaaacga tgaaaaaaga agcgaagcct caagaagtcg ttttgtctat
    17821 tgaaaatcta gtggtgaaag aaaatcgtgg attagaagcc gtgaaaaact tgaacttaga
    17881 ggttcgtgct ggcgaagtac ttggtatcgc tggaatcgat ggaaacgggc agtcggagtt
    17941 gatccaagct ttgactggtt tgcgaaaggc agaaagcgga catatcaagc taaaagggga
    18001 agacatcact aataaaaaac cccgaaaaat cactgaacat ggtgtaggac acgtgccaga
    18061 agaccgtcat aaatacgggt tagtcctaga tatgacatta tctgaaaata tcgcactaca
    18121 aacctatcat caaaaacctt acagtaaaaa cggcatgctg aattattcag taatgaatga
    18181 acatgccaga gaattgatcg aagaatatga tgttcgaaca acgaatgaac ttgttcccgc
    18241 aaaagcttta tcaggcggaa atcagcaaaa agcaattatc gctcgtgaag tcgaccgaga
    18301 tcctgatctg ttgattgttg caaatccaac tcgtggactg gatgtaggtg cgatcgaatt
    18361 tattcataaa cgtctgatcg aacaaaggga caaatacaaa gcagtgttac tgatcagttt
    18421 cgaattagaa gaaattttaa atgtttcgga tcgtattgct gttatccatg aaggagaaat
    18481 tgtcggtatc gttgatccga aagaaacatc tgaaaatgaa ttaggtctat tgatggcggg
    18541 ctatacctta gaagaagcac gaaaagagtt agaaaagggg gctggcgcac atgaatgatc
    18601 gcagcgaaaa attccgtaat ttattagtgc ctgtactttc agttgtttta ggattgatct
    18661 taggcgcgat attgatggct gcttttggtt ttcagcccat ccaaggttat tcttctatgc
    18721 tagatgcagc ccttggttcg caaagaggga taggtgaaac gttaaggcaa gcaacgccgt
    18781 tgatttttac agcattaggt ttttctgtag ctaactcagc tgggtttttc aatattgggc
    18841 tttctggaca agcactttgc gggtggatcg tcagtgtctg ggtggcactt gcgtttccag
    18901 atctgccaaa agttgttttg cttccgttat gcgtgatctt aggtgcctta gctggtgcga
    18961 tggcagcggc tgttccaggt ttacttcgag cattttttgg aacaagtgaa gtgatcgtaa
    19021 caatcatgat gaactatatc ttattatacg taagcacatt tgctttacat gaagtgatgc
    19081 ctgaaagcta tcgctcaagt ttggactctt ccaatatgat cagtcaaaat gcctcactgc
    19141 ggttaccatg gttaacacaa gcttttggcg gctctcgcgt aaactcagga ttatttttag
    19201 caatcatcgc gcttattttc gtttggctgc tgatgaagaa aacgacttta ggatttgaaa
    19261 tccgttctgt tggattgaat ccttttgctt ctgagtatgc aggaatgagt agtaaacgta
    19321 cgatcgtttt gtcgatggtc atttctggcg ctttggcagg gcttggcggt gtggttgaag
    19381 gattaggaac gtatcaaaac ttctttgttc aaacgacttc gctatctatt ggatttgacg
    19441 gaatggctgt ttccttgctt ggttctggat cagcaatcgg tattctttta tcagcgatct
    19501 tgttcagtat tttgaagatc ggtggacttg gcatgcagac aggagcaggt gttccgtttg
    19561 agatcgtcaa tgtatcgatt gctttgatta tcttctttgt cgggatcaac ttcctgattc
    19621 gtttcgtcat ggctaaagtc ttccaaggga aaaaacaaga agagatcgtt gcgacaatag
    19681 aatcgaaacc aacgaatcaa aaccatgaag ggggcgaact ataatgtcga ctatcgaatt
    19741 aattgccttg atccttactt ctacactggt ttattcaaca ccgctaattc taacgtcact
    19801 aggcggaact ttttctgaac gaagcgggat cgtaaacgta gggctagagg gaatcatggt
    19861 catgggtgct tttagttcca tcgttttcaa cttgacgatg agtccatcac ttggttctat
    19921 gacaccatgg atcgctattt tagtgggtgg cgtcgtaggt atcctatttt ctctgattca
    19981 cgcagtagca acagtcagtt tgcgtgctga ccatattatc agcgggacag taattaatct
    20041 gatggcacct gctttaggtg ttttcttgat caaagcatgg tatggtaaag gtcaaactga
    20101 taacatcacg cagaatctgg ggtatttttc tttcccagga ttagcagata ttccggtcat
    20161 tggaccaatt ttctttaaaa atacattctt acctgcttat tgtgctattt tgattgctgt
    20221 cctagcttgg gtgatcatct tcaagacgaa attcggcttg cgcctccgtt cagttggtga
    20281 aaatcctcaa gctgccgaca cattaggtat caatgtatat gctatgcgtt attcaggcgt
    20341 actgatttct ggcttgttag gcggtatggg cggtgctgtt tttgctcagt cgatttccgg
    20401 taacttttca gctggtacga tcgttggaca agggttcatc tccatggctg ctatgatctt
    20461 tggtaagtgg aatcctttag gggcaatggg tgcctcattg ttctttggtt ttgctcaaag
    20521 cttgagtatc attggcgcac aattaccagt tatttcttcg attccgccag tattgctgca
    20581 aattgctcca tatttgctga caatcattgt gctggttgtt ttcttaggga aagcttctgg
    20641 tccaaaagca aacgggaaga actatatcaa atcaaaataa tcttttagcg aataaaaagg
    20701 gtgggttacg ggaagtgttt ttcgtctcgc cctttttgtt ttaaaggcaa taaaaataaa
    20761 aagaaagaag gaataatcat gtttaaacgc gtacatctga tcgtcatgga ttcagtagga
    20821 attggagaag caccagatgc cgataagttc ggtgatgttg gttctgatac attaggacac
    20881 attgcgaaag aagcaggatt gaacgttcca catttagagc agcttggttt aggaacgatc
    20941 cgtcctcttg aaggtgtgga atcagtgaaa gatcatcaag gctatgcgac gaaattagaa
    21001 gaagtttctg tagggaaaga tacgatgaca ggccactggg aaatcatggg attgaatatc
    21061 aaaactccat ttcgtgtgtt tcctaatgga ttccctgatg atctgatcaa acaaatcgaa
    21121 gaattttctg gccgtaaagt cgtatgtaac aaaccttata gcggaacagc tgttattgac
    21181 gattacggtg aacaccaaat gaaaacaggc gatttaattg tatatacttc tgccgatcct
    21241 gtccttcaga tcgcggcaca tgaagaaatc attcctttag aagaattata tcggatttgc
    21301 caattcgttc gtgatataac aaaagatgat ccgtatatga ttggccgaat cattgcacgt
    21361 ccgtacgtgg gtgaaccagg agacttcaca cgaacaagca atcgccatga ttatgcgttg
    21421 aatccattcg gacacacagt ccttgattct ttgaaagaag caggaaagga cgtgattgct
    21481 gttggaaaga tcaacgatat tttcaacgga caaggaatca ctgaatctgt ccgcacgaaa
    21541 agcaatatgg atggcgttga ccagctgctg aaagttatga aaaacgattt ttcaggaatc
    21601 agctttacca atttagtaga ttttgatgca ttatacggtc atcgtcggga tgtagtcggc
    21661 tatgcgcatg cgattgaaga atttgactta cgaattccag aattgcttga agcgatggaa
    21721 gaagacgact tgctaatgat tacagccgat cacggaaacg atccgacgtt tactggtacc
    21781 gatcatacgc gagaatatgt accgttattg gtttacagta aaaaaatgaa agaacaaggg
    21841 gcattgcctc aaggatatta ttcagatatt tcagcaacga ttgctgagaa ctttagtgtt
    21901 tcttcgactg aaaatggcga aagcttcttg aaattattaa aataatcttt ttaaatagga
    21961 gaaagcaaat gaccaagtta agcgagatgt tacaagaaac gacccagttt atccttgata
    22021 aaggagtaaa agaaattgat tttggtttga ttctaggttc aggattaggt gaattagcag
    22081 atgaaatcga agatgctgta atgatttctt atgatgagat cccgttcttt cctgtttcga
    22141 cagtagttgg gcatgcagga aagctagttt atgggtctct ggcaggcaag aaagtgttag
    22201 ccatgcaagg gagattccac tactatgaag gtcattccat gcaaacagtg acctatccag
    22261 tacgtgtgat ggccggacta ggggcccatt cagtcattgt gactaatgca tgtggtggtg
    22321 tcaacgaatc atttgtacca ggagatttga tgctgattac cgatcatatc aattttactg
    22381 gtgaaaatcc tttgatcggt ccgaatgaag atgcaatggg ccctagattt ccagatatga
    22441 gtcaagctta tacgcctgac tatcaagcaa cagcaaaagc agcagcagaa aaactaggtt
    22501 tggatcttaa agaaggcgta tatatgggct attctggacc aacttatgaa acgcctgcgg
    22561 agatccgaat gtctcggaca ataggagccg atgcagtagg gatgtcgact gttccagaag
    22621 tcatcgtagc agctcacagc ggattaaaag tgttaggaat ctcttgtatt accaacttag
    22681 cagcaggtat gcaagcgaat ctgagccatg aagaagttgt agaaacaact cagagagtca
    22741 aacaatcttt taaagcattg gttaaagaaa cattgacatt attgtaatag gaggaacaat
    22801 aaaatgagtg tgcatattga agcgaaagaa ggcgagatcg ccgataagat tttacttccg
    22861 ggagatcctt tgcgagctaa atatattgcg gagacttttt tggaagatcc agtttgttac
    22921 aatcaggtac gcggtatgtt aggctttacc ggcaaatata aaggagaacg tatttctgtt
    22981 caaggaacag gaatgggaat gccatcagcc accatctatg cccatgaatt gatccagtcg
    23041 tatggtgtaa agaaattgat tcgagtaggt acatgcggtg cattgtcaaa agacgtccat
    23101 gttcgtgatt tagtactagc acaaggtgca gcgaccagtt cttcgatgat cgaaaaaaat
    23161 ttccaagcct ttcattttcc tccaatcagt gatttcaatc tattactgaa agcatatgag
    23221 atagctaaag aaaagggcta tacggttcat gtaggaaatg ttctttcgga agattctttc
    23281 tacaaagatg atttgacaga gacgttccaa ttagctgaac ttggcgtttt aggagtggaa
    23341 atggaagcag cggctcttta ttacttaggc gcgaaatacc atgtgcagac attaagtttg
    23401 atgaccgtta gcgaccattt gatcaccggt gaagaaacaa cagctgcaga acgtcaatct
    23461 acgttcaatg aaatgatcga agtaggattg gaaacagcga tagcagaata agaaggaaat
    23521 gaaaaagctg ccctgcatta agtaataaga acatccaagc aaaaatagct cctcatgttt
    23581 ttgacttggc tggacttatt attgcaaatg taagcttttg aacaccgttt accaagaggt
    23641 tgtgaatctg ccgtttaact ctgagtcaca aggaacaatt tcaaaaaaca gcttttcatg
    23701 tttgatgaat attgtgactt gtgaccgaga agttggcagg agaaaaccgt ttatacgaaa
    23761 aaagggactg tgacaaatcg tgtcacagtc ccttttttat agtgtttttt ataggtagta
    23821 ttttttagca actgttaagt catcatttaa ttcataaaca agtggttgac ctgttggaat
    23881 ttcaagatcc atgatgtctt cgtcagagat accttcgata tgtttagcta gggcgcgtaa
    23941 tgagttacca tgtgcagcta ctaaaacagt tttgttgtct agtaatgctg gagcaatttc
    24001 atcttgccag aatggcaaag cgcgttctaa tgtcactttc aagttttctc caccaggaat
    24061 atcgcgtttg tctaacattg cgtaacgacg gtcatttgct gcagaacctt cgtcagtttc
    24121 ttccattaat ggaggaagag tatcgtaaga acgacgccag atgtgcactt gttcgtcgcc
    24181 gtatttttca gctgtttctt ttttgttcaa accttgtaat ttaccatagt gacgttcgtt
    24241 taagcgccat gatttgattt gtggtaccca aagttgatct gaatattcta agatcaagtt
    24301 acatgttttg attgcacgag ttaaaacaga agtgtaagca acatcaaatt cgattccagc
    24361 ttctttgatt ttgcgtccgc cttcttttgc ttcttcgatt ccttctggtg ctagatttac
    24421 atcagcccaa ccagtaaatt ggttcaatgc attccattca ctaagaccgt gacgagaaaa
    24481 aactaatttt ggcatgttta gctctccttt taagataggt ttatatttct gaaattttca
    24541 gttctgtttt attgtacaat tttttggaag agatttccat cgaaaaatta gataagattc
    24601 tatgagaaaa caagtagaga atataaaaaa acgaacagtg cccacgcaac tgttcgtttt
    24661 taggtattag atgcataatt gctcgatttc tttttcaggt aaattgatat atttataaca
    24721 tgttccaact gaaacaccgc attttgaaga aataaattgg atcgtttctt ttttttcata
    24781 atagagacgt cggatttttt tgatcgtttt tgcatcgatt tttggtcttc cgccgatttt
    24841 tcctttttta cgagcttcat ctaatccaac taatgtacgt tctttgatca atgcgcactc
    24901 catgtttgct aggttttcca ttaattggaa atagattttt cccatttcgc gcgtatcgat
    24961 tccttcatca agactaatca agtgcagccc gcgatctttg aataattgcg tgagttctgt
    25021 taattgccgc gtagatttgc ctaatcgatg aagttggcaa atgactagtg catcgccttg
    25081 ttgcatgtca gcgatcactg actccaaatg aacagcagta gaatcatttt gttccacttc
    25141 atatgtctca tggaaaattt cttgacaacc aaagtcagat aattgatcaa cctgagttgt
    25201 taaatcaacg tcatttatgg ttgtgcgtgc ataaccaata attttcatgg tgattccttt
    25261 ctagcagtga ttttctaact ggatataaca gtaaaaatgt agcataaagt acgtcaaaaa
    25321 gatagttttt tcgcaaattt tccgctgtct ttttttattg gatgatcaag cagtttttct
    25381 ttatttacga cggattgcgt caagaatctc aacgcctttt tctgagccga caactacttt
    25441 agaaaccatg tttaggaaaa gcccatgttc tactacccca acaagttcat ctaaataggt
    25501 agctaagctt tctggctgtt cgatgacttc tagatgcaga tcaatgatgt aatgaccacc
    25561 atctgtggtt aagacttctc cgttttcgtc tgtacgcaag acgggttgga atcttttttc
    25621 ttcaaaaata tgaagtagct gttgggagcc ataagggatc acttcaactg ggagtgggaa
    25681 cttcccaagt ttatcgacta atttagaaga atcaacgatc caaatcgttt cttttgagta
    25741 cgtagcgact attttctcga aaagcaaagc agcgccgccg cctttgatcc cttgaaaatc
    25801 agcactgatt tcatcagcac cgtctattgt caaatcgact acggggactt catcaatact
    25861 ctttaacggt attcctaatt tttccgcttg ttcttttgtc gcatttgaag tagtaactcc
    25921 tgtgatacgt aaaccttctt cacgcatacg gcgaccaatc tcttctacca tataataggc
    25981 ggttgaaccg gtcccgagac ctacgatcat cccgtccttt acgaatttcg cggcttcaat
    26041 gccagctaat tgttttaaat tcatctttgc gtccaccttt ttttagtttg agcatcgtgc
    26101 tttcctcact attttagcgt gatttacggt aaaaagatac cattcttttt tattccaata
    26161 aagctttttc aaaaaaaatt gcatctcttg ttgacatgtt ttttcattcg tgatattcta
    26221 acaaaggtgc tttatctaca ggtttctgtg aagaaacgtg ctgactgttt atcaaagcat
    26281 atttgataag gatgcagaca ttgcatttat tttttatcac aaaaaaagaa ccacctggat
    26341 gtgtggaact agacgcaaat cgtgggaagg aggaaacaag gaatgcctac aattaaccaa
    26401 ttagtacgta aacctcgtaa atcaaaggtg gaaaaatcta attcacctgc tttgaacaaa
    26461 ggatataaca gctttaagaa aactcaaact aacgtaaact cacctcaaaa acgtggggta
    26521 gcaactcgtg tgggtacaat gacacctaaa aaaccgaact cagctttacg taaatatgca
    26581 cgtgttcgtt tgtcaaactt aattgaagtt actgcttata tcccagggat tggtcataac
    26641 ttacaagaac acagtgttgt attattacgc ggtggtcgtg taaaagactt accaggggta
    26701 cgttaccata tcgttcgcgg tgctttagat actgctggtg ttaacgaccg taaacaaagc
    26761 cgttctaaat acggaactaa aaaacctaaa gcttaatttt aattattaaa caaatgaaac
    26821 ttgcttctac tatatagaag taattactat gaacaatatt tcggaaggag gagttacgga
    26881 tgccacgtaa aggtcctgtt gcaaaacgtg atgttttacc agatcctatt tataactcaa
    26941 aattagtaac tcgcttgatc aaccgtgtaa tggttgacgg aaaacgcggg attgcagcta
    27001 acattatcta taatgccttt gacttgatca aagaatctac aggtaacgat ccattagaag
    27061 tgtttgaaca agcaatgaaa aacgttcaac ctgttcttga agttaaagca cgtcgtgttg
    27121 ggggttcaaa ctaccaagta ccagttgaag ttcgccctga acgccgcgtt actctaggtc
    27181 ttcgttgggt agtaaactac gctcgcttgc gcggtgaaca cacaatggaa gaacgcttag
    27241 caaaagaaat catggatgct gcaaacaaca caggtgcttc tgttaaaaaa cgtgaagaca
    27301 ctcataaaat ggctgatgcc aaccgtgcgt ttgctcacta tcgctggtaa gattctctct
    27361 gtttggtcgg cttttataag tcgacctcag atagtgtcct tatttttagc aactagatag
    27421 taaagagagg agaaacaagg agaatgacca gagaattttc tttacaaaac actcgtaata
    27481 tcggtatcat ggcccacatc gatgctggta aaacgactgc tactgaacgt atcttgtact
    27541 atactggtaa aatccataaa attggtgaaa ctcatgaagg agcttcacaa atggactgga
    27601 tggaacaaga acaagaacgt ggtattacga tcacttctgc tgctactaca gcacaatgga
    27661 agggtcaccg aatcaacatc atcgacacac caggacacgt agacttcaca gttgaagttg
    27721 aacgttcatt gcgtgtactt gatggtgctg taactgttct tgatgcacaa tcaggtgttg
    27781 aacctcaaac tgaaacagtt tggcgtcaag caacaactta tggtgtacct cgtatcgtat
    27841 ttgcaaacaa aatggacaag atcggtgctg acttcttata ttcagtatca actttacatg
    27901 accgtttgca agcaaacgct cacccaatcc aattaccaat tggtgcggaa gacgacttca
    27961 caggaattat cgaccttgta acaatgaagg ctgaaatgta tacaaacgat cttggaacag
    28021 agatcgaaga aacagaaatt cctgaagaat accgcgaatt agctgaagaa tggcgcgaaa
    28081 aattggttga agctgtagct gaaactgatg aagaacttac tttgaaatac ttagaaggtg
    28141 aagaaatcac tgaagctgag ttaaaagaag gtatccgccg cgcaacagtt aacgtagaat
    28201 tctacccagt actatgtggt tcagcattta agaacaaagg ggttcaatta ctattggacg
    28261 ctgttcttga ttacttgcca tcaccgttag atatcccagc tatcaaaggg attgacccta
    28321 aaactgatga agaagtagaa cgtcctgcag acgacagcgc tcctttctca gctttagcat
    28381 ttaaagttat gactgaccca ttcgtaggtc gtttaacttt cttccgtgtg tactctggtg
    28441 ttttacaatc aggttcatac gtacaaaacg caacaaaagg caaacgtgaa cgtgttggtc
    28501 gtatcctaca gatgcatgcc aactctcgtt cagaaatctc tgaagtttac gctggagata
    28561 tcgctgctgc tgttggtttg aaagacacaa ctactgggga cacactatgt gatgaaaaga
    28621 gtctagttat tcttgaatcc atggaattcc cagaaccagt tatccaagtc gctattgaac
    28681 ctaaatcaaa agctgaccaa gataaaatgg gtgtggcttt acaaaaacta tctgaagaag
    28741 atcctacttt ccgtgctgaa acaaacgtgg aaacaggcga aacaatcatc gctggtatgg
    28801 gtgaacttca cttagatatc atcgttgacc gtatgcgtcg tgaattcaaa gttgaagcta
    28861 acgtaggtgc gcctcaagta tcttaccgtg aaactttccg tgctggcact caagccgaag
    28921 gtaagtttgt acgtcagtct ggtggtaaag gtcaatacgg tcacgtatgg attgaattta
    28981 caccaaatga agaaggtgct ggtttcgaat ttgaaaatgc gatcgtcggt ggggttgttc
    29041 ctcgtgaata cattccagct gttgaaactg gtttgaaaga tgctatggaa aatggtgtct
    29101 tagctggcta tccattagta gatatcaaag ctaaacttta cgatggttca taccatgatg
    29161 tcgattcaaa tgaaactgcc ttccgtgttg ctgcttctat ggcattacgt gcagcagcta
    29221 agaaagctaa tccagtaatc cttgaaccaa tcatggctgt agaagttgtt atccctgaag
    29281 attatttagg tgatgttatg ggtcacgtaa ctgctcgtcg tggacgtgtt gaaggtatgg
    29341 aagctcgcgc tggcggccaa caagttgttc gtgcgatggt tccacttgct gaaatgtttg
    29401 gttatgctac aactcttcgt tctgctactc aaggtcgtgg tacatttaca atgacatttg
    29461 accactacga agatgtacca aaatcagtac aagaagaaat cattaagaaa aacggcggaa
    29521 aagctgaata atttcttaaa accggatagt cctgcaaaga gattatccaa agagactata
    29581 tttttaatat agtttcgtgt aaaataatta tcgatgatat gggcatgtgg tgtaccttgt
    29641 gtacatcata tacctatcag acaaataaaa aatatattgt atttttagga ggacatttta
    29701 aaatggcaaa agaaaaattt gaccgttcta aaccacacgt taacattggt actatcggac
    29761 acgttgacca tggtaaaact acattaacag ctgcaatcac aactgtacta tctaagaaaa
    29821 acggcggcca agctatggct tacgatcaaa tcgatggtgc tccagaagaa cgcgaacgcg
    29881 gaatcacaat ctcaacagct cacgttgagt atgaaacaga tacacgccac tacgctcacg
    29941 ttgactgccc aggacacgcg gattacgtta aaaacatgat cactggtgct gctcaaatgg
    30001 acggagctat cttggtagtt tctgctgctg acggcccaat gcctcaaact cgtgaacaca
    30061 tcctattgtc tcgtcaagtt ggtgttcctt acatcgttgt attcttgaac aaagtagaca
    30121 tggttgatga cgaagaatta ctagaattag ttgaaatgga agttcgtgac ctattaacag
    30181 aatacgaatt ccctggtgac gatgttcctg tagttgctgg atcagctttg aaagctctag
    30241 aaggcgacgc ttcatacgaa gaaaaaattc ttgaattaat ggctgcagtt gacgaataca
    30301 tcccaactcc agaacgtgac aacgacaaac cattcatgat gccagttgaa gacgtgttct
    30361 caattactgg acgtggtact gttgctacag gtcgtgttga acgtggacaa gttcgcgttg
    30421 gtgacgaagt tgaagttgtt ggtattgctg aagaaacttc aaaaacaaca gttactggtg
    30481 ttgaaatgtt ccgtaaattg ttagactacg ctgaagctgg agacaacatt ggtgctttac
    30541 tacgtggtgt tgcacgtgaa gacatccaac gtggacaagt tttagctaaa ccaggtacaa
    30601 tcacacctca tacaaaattc tctgcagaag tatacgtgtt gacaaaagaa gaaggtggac
    30661 gtcatactcc attcttcact aactaccgtc cacaattcta cttccgtaca actgacgtaa
    30721 caggtgttgt tgaattacca gaaggaactg aaatggttat gcctggcgac aacgtaacaa
    30781 tggaagttga attaatccac ccaatcgcta tcgaaaacgg tactaaattc tcaatccgtg
    30841 aaggcggacg tacagttggt gccggtgtcg ttacagaaat caaagcttaa ttcacttaag
    30901 ttttaaagta aagcaacatt tattcggacg taatcgctcg gaacgaaggt cttaggatct
    30961 ttgttccgag cttttttatt tattgcagga tcaggaaaaa agacaggagt attataaata
    31021 gaagaaacac gaaataaaag agtcagtatt ttctaaatga aactttatga aaacaaaatg
    31081 ttttttacaa gaaaaagcct tgctttgtga gtttatatat attataatga caaaggtgcg
    31141 tttactttag tgaattgcac agacgtaatc agaatgattt cgtcggctaa gaaacgagag
    31201 gttgcgacac gcccggacgc tttgccacga acgagcgtga cggaaatttt cgtggagcta
    31261 tgtctacttt tcaaaatagg cgaaggaggg aacaagatgg caaaacaaaa aattcgtatc
    31321 cgtttaaaag cgtatgaaca ccgtatttta gatcaatcag cggataaaat cgtggaaact
    31381 gcaaaaagaa ctggagctag cgtgtctggt ccaattccat taccaactga acgcagtctt
    31441 tacacaatca tccgtgcgac tcataaatac aaagattcac gcgaacaatt cgaaatgcgt
    31501 acacacaaac gtcttatcga cattgtgaac ccaacaccaa aaactgttga tgctttgatg
    31561 aagctagact taccatctgg tgtaaacatc gaaatcaaat tataaaacta aaacaaaaat
    31621 aatggaggtg tactcatgac caaaggaatc ttagggaaaa aagtgggaat gacacaaatc
    31681 ttcactgaat ctggtgaatt aattccagta actgttgtag aagctactcc aaacgtagta
    31741 ctacaagtga aaacaatgga aacggatggc tacgaagcta ttcaagttgg ttaccaagat
    31801 atgcgtgaag ttttatcaaa caaacctgcg aaaggtcatg ttgcaaaagc aaacacggct
    31861 cctaagcgct tcattcgtga attcaaaaat gttgagctag gagaatatga agtaggaaaa
    31921 gaaattacag tagatgtttt ccaagcagga gacattattg atgtaacagg tactacgaaa
    31981 ggtaaaggat tccaaggggt tatcaaacgc cacggacaaa gccgcggacc aatggctcac
    32041 ggttctcgtt accatcgtcg tcctgggtca atgggtccag ttgcacctaa ccgtgtattt
    32101 aaaaacaaac gtcttgctgg ccgtatgggt ggcaaccgcg taactatcca aaacttggaa
    32161 gttgtacgtg tcgatgcaga aagaaatgtt atcttgatca aaggtaatgt tcctggagct
    32221 aaaaaatctt taattactat caaatcagct gtgaaagcta aataattgta ggaagaaagg
    32281 aggaactaag gaatgccgaa tgtagcatta ttcaaacaag atggaagcca aaacggtgaa
    32341 atcacactta acgaagaaat cttcggaatt gaacctaatg aaagtgttgt ttacgatgca
    32401 atcgtaatgc aacgtgcgtc attaagacaa ggaacacacg cggttaaaaa ccgtagcgct
    32461 gttcgcggcg gcggacgtaa accatggcgt caaaaaggaa caggtcgtgc acgtcaagga
    32521 tctatccgct caccacaatg gcgtggaggt ggcgtagtct ttggaccaac accacgttct
    32581 tacagctaca aacttcctaa aaaagttcgt cgtttagcaa tgaaatctgt attgtcagaa
    32641 aaagttgctg aaaacaactt ggtagcaatc gaaggcttga acttcgacgc accaaaaaca
    32701 aaagaattca aacaagttct tgctaactta tctatcgact ctaaagtatt ggttgttcta
    32761 gaaaaaggta acgactttgc tgctttatca gcacgtaact taccaaacgt ttctgtagta
    32821 acttctgata atgtgagtgt gctagacgtt gtatcaaata caaaagtgtt agcaacacaa
    32881 actgctctta ctcaaattga ggaggtgctt gcataatgaa cttactagac gtaatcaaac
    32941 gcccagtgat cactgaaaaa tcaatgcttg ccatggatga caagaaatac acttttgaag
    33001 tggacactcg cgcaaacaaa actttagtaa aacaagcggt agaagctgct tttgacgtta
    33061 aagtcaaaaa cgtgaacatc gtgaacgtac gtgcgaaatt caaacgtatg ggcaaatatg
    33121 caggatatac aaaaaaacgt cgcaaagcga tcgttacatt gactgaagat tcaaaagaaa
    33181 tccaattatt cgaagctgct gaataagcac taatagataa ctcattaaat taggagggaa
    33241 aaacgtggcg attaaaaagt acaaacctac ctcaaatggt cgtcgtaaca tgacaggttc
    33301 tgattttgct gaaatcacaa catcaacacc tgaaaaatca ttgttacaac cattgaaaaa
    33361 ccatgctgga cgtaacaaca acggccgcat cactgtacgt catcaaggtg gcggacacaa
    33421 acgccaatat cgcgtgatcg acttcaaacg taacaaagat aacgttgttg caactgttca
    33481 aacgatcgaa tatgatccaa accgttcagc taacatcgcg ttagtacact atgaagatgg
    33541 agtgaaagct tacatcttag cacctaaagg actagaagtg ggtatgaaac ttgtttcagg
    33601 tccagaagca gatatcaaag tcggaaatgc tcttccatta gaaaacattc cagttggtac
    33661 tgttatccac aacattgaaa tgaaacctgg taaaggtgga caattgatcc gttctgctgg
    33721 tacaagtgct caagtacttg gtaaagaagg caaatacgta ttgatccgct tgaactctgg
    33781 tgaagttcgt atgatcttag ctgcatgccg tgctacaatc ggttctgtag gtaacgaaca
    33841 acacgaatta atcaacatcg gtaaagctgg acgctctcgt tggatgcgta aacgcccaac
    33901 tgtacgtggt agcgtaatga accctaatga tcacccacac ggtggtggtg aaggtaaagc
    33961 tcctatcgga cgtaaagcac cagtttctcc ttggggtcaa ccagctcttg gttacaaaac
    34021 tcgtaacaaa aaagctaaat cagacaaact tattgttcgt cgtcgcaaaa ataaataatt
    34081 actttgacca tgtgtcgcac attttgagag gaggttcacc atgggtcgta gtttaaagaa
    34141 aggacctttt gtcgatgagc atttaatgaa aaaagttgaa gctcaagcag gggttgaaaa
    34201 gaaaaaagtt atcaaaactt ggtcacgccg ttcaacagtt ttcccaagtt ttgttggata
    34261 taccatcgca gtttatgatg gacgtaaaca tgtaccagtt tacatccaag aagacatggt
    34321 aggacacaaa ttaggtgaat ttgcacctac aagaacttat cgtggacatg ctgctgacga
    34381 taagaaaacg aaacgctaat ttgaggggag gataaatcca aatggcagaa caaatcacat
    34441 cagctaaagc aactgcaaaa acagttcgca cttcacctcg aaaagcccgt ttagtaattg
    34501 accttatcag aggtaaaagt gtcgcagatg caatttcaat cttgaaattc acaccaaaca
    34561 aatctgctgg aatcattgaa aaagtattga tgtcagcagt tgcgaatgca gaaaataact
    34621 ttgacttaga tgttgaaaac ttggtagtaa gcgaagcttt tgttaacgaa ggacctacaa
    34681 tgaaacgttt ccgtcctcgt gcaaaaggat cagcttctcc aatcaacaaa cgtacaagtc
    34741 atatcacggt agtcgtatca gaaaaataag gagggataat cagtgggtca aaaagtacat
    34801 ccaattggaa tgcgtgtagg catcatccgc gactgggatg ctaaatggta tgctgaaaaa
    34861 gagtatgctg agttcttaca cgaagattta agaatccgta aatttatttc aactaaactt
    34921 gctgatgctg ctgtatcaac agttgaaatc gaacgcgcaa caggtcgcgt aaacatttca
    34981 attcacacag ctaaaccagg tatggttatt ggtaaaggcg gttctgaagt cgaaagccta
    35041 agaaaagaat taaacaaatt aactggtaaa agaatccata tcaatatcgt ggaaatcaaa
    35101 aaaccagatc tagatgcaaa attagtaggt gaaggaatcg cacgtcaatt agaaaaccgt
    35161 gttgctttcc gtcgcgctca aaaacaagcc atccaacgct caatgcgtgc tggcgctcaa
    35221 gggatcaaaa ctcaagtatc tggtcgtcta aacggagcag atatcgctcg ttcagaagga
    35281 tactcagaag gaactgttcc tcttcatact ttacgtgcgg acattgatta cgcatgggaa
    35341 gaagcagata caacatacgg aaaactagga gttaaagtgt ggatctatcg tggagaaatt
    35401 cttccaacta aaaaaaacac tgagaaagga gggaaataat catgttagta cctaaacgtg
    35461 taaaacaccg tcgtgaattc cgcggaaaaa tgcgcgggga agctaaaggc ggaaaagaag
    35521 tagcattcgg tgaatacggt ttgcaagctg ttgattcaca ttggatcaca aaccgccaaa
    35581 tcgaagctgc tcgtatcgca atgactcgtt acatgaaacg tggtgggaaa gtatggatta
    35641 aaattttccc tcacaaatct tatactgcca aagcaattgg ggtacgtatg ggttctggta
    35701 aaggggcacc tgaaggatgg gttgcaccag taaaacgtgg taaaatcatg tttgaaatcg
    35761 caggcgttcc tgaagaagta gctcgtgaag cgttacgtct agcttctcac aaattaccaa
    35821 tgaaaactaa gatcgtaaaa cgtgaggaaa tgggtggtga atcgaatgaa ggttaaagaa
    35881 atcagagaat taaccactgc cgaaatgctt gatcaagaaa aacaattaaa agaagaattg
    35941 tttaatctta gattccaatt agcaacaggt caattagaaa acactgcacg tattaaagaa
    36001 gtacgtaaat cgattgcacg catcaaaact gtgttgcgtg aacaagctaa gtaattatgg
    36061 aaggaggcca ttaagcgtat gactgaagga agaaatcaac gcaaagttta tcaaggtcgc
    36121 gtggtttcag acaaaatgga taaaacaatt accgttgctg tcgaaacaaa gaaaaaccac
    36181 cctatctatg gcaaacgcat gaactattct aagaaataca aagtgcatga tgaaaacaac
    36241 acagcaaaag ttggcgacat cgtgagaatt atggaaactc gtccattatc agctacaaaa
    36301 cgtttccgtt tgttggaagt agtcgaagaa gcagttatta tctaataaca cgagattttc
    36361 ctatatagat tgaatgcaaa atctgaaagg aggatacaca acgtgatcca agcagaaagt
    36421 cgtttaaaag tcgctgataa ctcaggcgca cgtgaaattt tgacgatcaa agtccttggt
    36481 ggatctggtc gtaaaactgc taacatcggt gatgtgatcg ttgctacggt taaacaagca
    36541 acgccaggtg gggttgtcaa aaaaggtgac gtcgttaaag ccgttatcgt tcgaacaaaa
    36601 tcaggagctc gtcgtacaga cggttcatat attaaatttg atgaaaatgc tgcagtgatt
    36661 attcgtgatg ataaaagccc tcgtggaaca cgtatctttg ggccagttgc acgtgaacta
    36721 cgtgaaaaca acttcatgaa gatcgtttca ctagcaccag aagttttata atcttgagac
    36781 acttatcaaa ggaggtgcga aacagttatg tttgttaaaa aaggcgataa agttaaagtt
    36841 atcactggaa aagacaaaaa caaagaaggc gttgtactag cagcgttccc gaaaaaagat
    36901 aaagttattg tcgaaggtgt aaatgtcgtt aaaaaacacc aaaaaccttc tcaagctgct
    36961 cctcaaggtg gaattgttga gatggaagcg ccaattcatg tttctaacgt gatggtggtt
    37021 gactctactg gtgtagctgg ccgagttggc tacaaagaag tagacggcaa aaaagtccgt
    37081 gtttctaaaa aaaccggtga agttttagat aaataaaagt ttaaggaagg agggtcttac
    37141 tgaatgaacc gcctaaaaga aaaatatctt aaagaagtaa ctccatcatt gatggaaaaa
    37201 tttaactata gctctgttat gcaaacacct aaagttgaaa aaatcgtcat caacatgggt
    37261 gttggtgatg cggtatcaaa cgctaaaaac ttagataaag cagttgaaga attaactttg
    37321 atcactggtc aaaaaccaat gattacaaaa gctaaaaaat caatcgctgg attccgttta
    37381 cgtgaaggaa tgccaattgg tgcaaaagtt acattgcgcg gagaaagaat gtacgaattc
    37441 ttagacaaat tggtttctgt ttcactacca cgtgtacgtg acttccatgg tgtaagtaaa
    37501 aaagcctttg acggtcgtgg aaactatact ttaggtatta aagaacaatt gatcttccca
    37561 gaagtagatt atgatttagt agataaagta cgtggtatgg acatagttat tgtaacaaca
    37621 gcaaactctg atgaagaatc tcgtgagttg ttgacacaat taggcatgcc attccaaaaa
    37681 taattaaagg aggcgaacta cgtggctaaa aaatcaatga ttgctaaaaa caaacgtcct
    37741 gcaaaatttt caacacaagc ttatactcgt tgcgaacgtt gcggacgtcc acattcagtt
    37801 tatcgtaagt tccatctttg ccgtatttgc ttccgcgaac ttgcctataa aggtcaaatt
    37861 cccggcgtga agaaagctag ctggtaaaaa gtaaattcgc ataagaagga ggtaaaagat
    37921 caatggtcat gacagatcca attgcagatt ttctaactcg tatccgtaac gcaaacatgg
    37981 ttaaacatga gtctttagaa gtacctgcat caaaaattaa acgtgacatc gctgaaatct
    38041 tgaaacgtga aggtttcgtt cgtgatgttg aatacatcga agatgacaaa caaggcgtga
    38101 tccgtgtttt cctaaaattt ggtaaaaacg gcgaacgtgt tatcacaaac ttaaaacgta
    38161 tctctaaacc aggtttgcgt gcttatgtca aagctgacga agtaccaaaa gtattgaacg
    38221 gtttaggtat cgcaatcatt tcgacttctg aaggtgttgt cactgataaa gaagctcgtg
    38281 aaaaaaatat cggcggcgaa gttatcgctt acgtatggta atcaagtaga atctacaagg
    38341 aggtgtcttt aagtgagccg tatcggaaat aaagtcgttg ttatccctga aggagtaaca
    38401 gttactcaag acggaaacaa cgttacagtt aaaggaccaa aaggtgaatt gactcgtact
    38461 ttttcagcag atatcaaaat gaatatcgaa ggaaacgaag taactttcac tcgtccaaac
    38521 gacagtaaag aaatgaaaac aattcatgga acaactcgtg cgaacttcaa caacatggtt
    38581 gtaggtgtca gcgaaggttt ccaaaaagcg ttagaactaa tcggggttgg gtaccgtgca
    38641 caattacaag gatcaaaact tgtattgaac gttggttact cacatccagt agaaatcaca
    38701 ccaccagctg gagtaactgt tgaagtacca gctaacacac aagtaattgt taaaggtgcg
    38761 aacaaagaag aagttggcga attagctgca aacattcgtg gaactcgtcc tccagaacct
    38821 tataaaggta aaggtattcg ttatgttggc gaatatgtac gccgtaaaga aggtaaaact
    38881 ggtaaataat cgtttagaaa aattgcatag aagccagcag caggaaaaag gcatttggct
    38941 gaagtttacc ttcaaaaaaa tacattttta cttgtgccgc agcttctatt tttcgaaacg
    39001 tatttactgc ttgaaatagt agtacaataa aaataaagag gtgacaattg tgattacaaa
    39061 accagataag aacaaaacac gtcaaaagag acatcgtcgt gtacgtaaca atatctctgg
    39121 tactgctgag cgcccacgct tgaacgtttt tcgttctaac aaaaacatct acgctcaaat
    39181 tattgatgac gtagcgggtg taacgctagc aagtgcctct accttggata aagaaatttc
    39241 aggtggaaca aaaacagaag cagcacaagc tgtcggtaaa ctagttgctg aacgtgcagc
    39301 tgaaaaaggc attaaagtag tagtctttga ccgtggtgga tacctttacc atggccgtgt
    39361 gcaagcttta gctgaagctg ctcgcgaaaa tggactagaa ttttagaaga aggaggaata
    39421 ccattcatgg tttatatcga tccaaaacat ttggaattag aagaccgcgt tgttgcaatt
    39481 aaccgtgtaa caaaagttgt taaaggtgga cgtcgtctac gttttgctgc tttagttgtt
    39541 gtcggtgaca aaaacggaca cgtagggttt ggtacaggta aagctcaaga agttcctgaa
    39601 gcaatccgta aagcaattga agatgcgaag aaaaacttag ttgaagtacc tatggttggt
    39661 tcaacaatcc cacacgaagt aatcggtgct tttagtggtg gtagaatcct aatgaaacct
    39721 gctgtagaag gttctggggt tgctgctggt ggaccagttc gtgccgtatt agaattagct
    39781 ggggtagcag atatcacttc taaatcttta ggctcaaata caccaatcaa cgttgttcgc
    39841 gcaacagttg aaggtttgaa acaattgaaa cgtgcagaag aagttgcaga acttcgcggc
    39901 aaatcagttg aagaattaat cggataagga ggacaacaat aatggctgaa ttaaaagtta
    39961 ctttaaaacg cagtattatc ggacgtcctc aaaaccaacg cgatacagtt aaagcgttag
    40021 gtcttacaaa gattaacagt tcagtggtta agccttctaa tgaagcaatt aaaggcatga
    40081 tcaatactgt ttctcaccta gtggacgttg aagaaattta atttagaaaa atcataacta
    40141 gaacattaag gaggtgccaa acctatgaaa cttcatgaat taaaacctgc tgaaggttca
    40201 cgccaagtac gtaaccgtgt tggtcgtggt acttcatctg gtaacggaaa aactgccgga
    40261 cgcggacaaa aaggacaaaa agctcgttca ggcggcggtg tgcgtttagg atttgaaggg
    40321 ggacaaacac cattgttccg tcgtttacca aaacgaggat tcacaaacgt gaaccgtaaa
    40381 gactatgcag tcattaatct tgatgtattg aaccgctttg aagacggagc tgaagtaact
    40441 cctgttgctt tagttgaagc tggaatcgtg aaaaacgaaa aagctggaat caaagtatta
    40501 gctaatgggg aactaaacaa gaaattaact gtgaaagcag caaaattctc taaagcagct
    40561 caagaagcaa ttgaagcggc tggtggatca atcgaggtga tctaatgttt agactattaa
    40621 aagatgcttt taaagtaaaa gacattagat cgaaaatcct atttactgta tttgtgttgt
    40681 ttgtatttcg cctaggtgca catattactg taccaggcgt aaatgctgct tcattgcaaa
    40741 acctttcttc tttgccattt ttcaacatgt tgaacttggt aagtggtagt gcgatgcaaa
    40801 acttttccat tttctcaatg ggggtttcac catacattac tgcttctatc gtcattcagc
    40861 ttcttcaaat ggacatcgtg cctcgatttg ttgaatggtc gaaacaaggg gaagttggtc
    40921 gtaaaaaact gaatcaagcg actcgatatc tgacattagt attggcattt atccaatctg
    40981 tcggtatcac tgctggattc aatcaatacg ctcaattagg tttcgtgaat aatcctaacg
    41041 tagcaactta cgtaacgatc ggtttgattc taacagccgg tacgatgttt gttacttggc
    41101 taggagaaca gatcacagaa aaaggtatcg gaaatggcgt atcaatgatc atttttgcag
    41161 gtatcatttc tagattgcct gaaagtatca gagaaattta tgaagattac tttataaata
    41221 ttgatccttc agacatatgg aaatctgcta tttttgtggc cattttacta gtagcggtct
    41281 tgttgatcgt gacattcgta acatttttcc aacaagctga acgcaagatc ccgatccaat
    41341 atacgaaacg cgtagctggc gcgcctacaa gcagctatct gccgttgaaa gtaaatgcag
    41401 ctggagttat tccagttatc tttgctagtt cgtttattgc tacgccaaat gctgttttac
    41461 aagcattgag cggtagattc ggttctgaaa actggtacaa agtgatgatg gagatcttta
    41521 actataatac agcacctggt gctacgattt atacgattct gatcgttgcc ttcactttct
    41581 tctacgcctt tgttcaagta aaccctgaga aattagcgga aaacttgcaa aagcaaggaa
    41641 gttatatacc aagcgtacgc cctggtaagg ggactgaaga gtatgtctca agattactga
    41701 tgcgtttaag tacagttggt gcagtcttcc ttggtttagt ggcattgctt ccaatcattg
    41761 ctcaaatggt ttgggatctt ccacaatcaa tcggattagg cggtacaagc ttactgatcg
    41821 ttatcggtgt agctttagaa actgcgaaac agttagaagg cttaatgctg aaacgtaaat
    41881 atgttggatt cattgagtaa gaaagcgtgt tgaggtttcc cctcaacaca cgttctcaca
    41941 catttattag gagggaaaac aatgaacctc attttaatgg ggctgccagg cgcaggtaaa
    42001 ggaacacaag ctgaaaaaat cattgatgct tatggtattc cgcacatctc aacaggagat
    42061 atgttccgcg cagcgatgca aaacgaaaca gctcttggcc tggaagcaaa gtcttatatg
    42121 gataaaggtg cattagttcc tgatgaagta acaaatggaa tcgtgaaaga gcgactagct
    42181 gaaccagata cagagaaagg cttcttatta gatggctttc cacgtacgct agatcaagca
    42241 aaagctctgg acgcaatgct aaaagatttg aataaaaaaa ttgatgctgt catcgatatc
    42301 catgttggtg aagaaatctt ggtcgaacgt ctagccggcc gatttatctg cagcaattgt
    42361 ggagcaactt accataaaat tttcaaccct acaaaagttg aagacacatg tgatcgttgc
    42421 ggtgggcatg aattctatca aagagaagat gataaacctg agacggttaa aaatcgtctg
    42481 gctatcaaca tcaaaaatag tgaaccaatc ttggcttatt ataaagaaca aggtttgcta
    42541 aacactattg atggtgctcg tgaaatcgat gctgtatttg cagatgtaca aaaaatcatt
    42601 gaaaaatagc acgattgccc gtagccgact tgcattatgc agttactctt gtcaagttca
    42661 ataaattatg atagaatatg tcagtccgac ttctagagaa tcctctagat gatccatttt
    42721 gagaattttg aggtgggaac tgcagtttcc gccattttat cgtgtgaaaa tgcgaaacaa
    42781 gtacaaggag gtactgtgcg tggcaaaaga agatatgatt gaagtcgaag gtacagtcgt
    42841 cgaaactttg ccgaatgcaa tgtttaaagt tgaactagaa aacggacacc aagttcttgc
    42901 tactgtttca ggtaaaattc gtatgcatta catccgtatc ttacctggtg acaaagtaac
    42961 ggttgaattg tctccatacg atcttaaccg tggccgtatt acttatcgct ttaaataatt
    43021 gtactccgta aaactacagg aggtattatc atgaaagtaa gaccatcagt aaaaccaatg
    43081 tgcgaacatt gtaaagtaat tcgtcgtaaa ggacgcgtta tggtgatttg cccagcaaat
    43141 ccaaaacata aacaacgtca aggataattg gaggtgctat aaatatggct cgtattgcag
    43201 gagtagatat tcctcgtgat aaacgtgtag tagtttcact tacttatatc tatggtattg
    43261 gtaacactac tgctaaaaag atcttagctg atgctggtgt atctgaagat gttcgcgttc
    43321 gtgaattaac gaatgaacaa acagatgcta tccgtgcaga agtagataaa ttaaaagttg
    43381 aaggggatct tcgtcgtgaa gtgaacttga acatcaaacg tttgatggaa atcggttctt
    43441 accgtggaat ccgtcatcgc cgtggattgc ctgttcgtgg acaaaacacg aaaaacaatg
    43501 cacgtactcg taaaggccca gctcgcgcta tcgctggcaa gaaaaaataa ttcttaagtg
    43561 aaggaggtta aaacttcatg gcagcaaaaa aagtgaatcg taaacgccgt gtgaagaaga
    43621 atatagaagc aggtattgca catatccatt ctacattcaa taacactatc atcatgatca
    43681 ctgatactca cggaaatgca ttagcgtggt catcagctgg ttcattaggt ttcaaaggaa
    43741 gcaaaaaatc aactcctttt gccgctcaaa tggcagcaga aactgctaca aaagcagcaa
    43801 tggaacacgg attaaagact gttgaagtaa cagttaaagg acctggttct ggacgtgaag
    43861 cagcaattcg ttcattacaa gctacaggtt tagaagtgac tgcaattcgt gacgtgactc
    43921 cagttcctca taatggtgcc cgccctccaa aacgccgtcg tgtttaatga gtgccgctca
    43981 ttttgagttt tatcagtaac gtcattgaac aagacacttt tcgttttgaa aggggtaaag
    44041 ataagaatga ttgagttcga aaaaccaaga atcgcaaaaa ttgatgaaga aaaagattat
    44101 ggcaagttca tcgttgaacc tcttgaaaga gggtatggga ctactttagg gaattcccta
    44161 cgtcgtattt tattatcttc tttgccaggt gctgccatca ctaatattca aatcgatggt
    44221 gtactgcatg aattctctac catcaaaggt gttagagaag acgtcactca aatcatcttg
    44281 aacattaaag gcttagcgct gaaaatgtat ggccaagaag aaaaaaccct tgaaatcgat
    44341 attaccggac ctgctacagt aactgctggc gatattatcg ttgatagtga tgtagaaatt
    44401 cttaacaaag atatgtacat ctgtagtgtc tctgaaggag ctacgttcca tgctcgctta
    44461 acagtgaaac ctggacgtgg ttatgttcaa gcagatgaaa ataaaaaaga agatatgcca
    44521 attggcgttc ttccagtcga ttcaatctac acacctgttc gtcgtgtgaa ctatcaagtt
    44581 gagaacacac gtgttggaca ccgtgaagat tttgataaat tgacgatgga gatttggaca
    44641 gatggttcaa ttgaaccgtt ggaagcaatg agtttgtctg cgaaaatcat gactgaacat
    44701 ttggatattt ttgtgaactt aactgatgaa gcaaaaaatg ctgaaatcat ggtcgaaaaa
    44761 gaagaaacac aaaaagaaaa aatgttggaa atgacgatcg aagagttaga cttgtctgtt
    44821 cgctcttaca attgtttgaa acgtgcagga atcaatactg tacaagaact tacaaataaa
    44881 tctgagcctg aaatgatcaa agtccgtaac ttaggacgta aatcattaga agaagttaaa
    44941 gcaaaattgc acgacttagg tttaggttta cgtaaagaag attaaaacct tttacgaagg
    45001 agggaaacca acgtgagtta tcgtaaacta ggacgcacat ctagccaacg taaagcgatg
    45061 ttgcgtgatt taacaactga tttattaatc aacgaacgta ttgtgactac tgaagctcgt
    45121 gcgaaagaag ttcgctcaac tgcagaaaaa atgatcactt taggtaaacg cggagatttg
    45181 catgcacgtc gtcaagctgc ggctttcgta cgtaatgaag ttgccagcgt gcgtgaagaa
    45241 aatgaggaca tcgtcattga atcagcttta caaaaactgt tcaacgatat tgcacctcgt
    45301 tacgcagaac gtcaaggcgg atacacacgc attttgaaga cagaaccaag acgcggtgat
    45361 ggtgcaccaa tggttgtctt agaacttgtc taaaatcaca ctaataacat cactttatag
    45421 atgattcttt tagagtgtta tgatgttgga agatattttt ccgagtctag ctcagcgctg
    45481 ctcctcaagc gaatatcgct tggggagtaa gcactcatca taaagtgttt ttttatacct
    45541 tcaattacct gtcatgacag atatgtttga aggcataaaa aaacatttta agcgagaaat
    45601 aattgaaaat tttgtctttt tttgatagtg ttagtaggaa ctttaggatg aagaaggagt
    45661 aatcatggag ccaattattg aattagaaaa gataaattat aaataccagc cagatgatct
    45721 tcgccccgca ttgaaagatg tctcctttac aattgataaa ggtgagtgga tcgctattat
    45781 tggacacaat ggttcaggaa aatcgacact tgccaaaacg atcaatggat tgcttctgcc
    45841 agaatcaggg atcgtgaaag tgggaaatca aatattggat gaagaaaata tttggacgat
    45901 ccgacagatg gttggaatga tttttcaaaa tccagacaat cagtttgttg gttcgacagt
    45961 agaagatgac gttgcttttg gtcttgaaaa tcaagggatt cccagagaag aaatgctagt
    46021 gcgtgtgaaa gatgcacttg agaaagttag aatggctgag tttgcttcac gcgagcctgc
    46081 tcgtttatca ggagggcaaa aacaacgtgt tgccattgcc ggcgtggttg ccttacgacc
    46141 tgatatcatt attttagatg aagcaaccag tatgctagat ccagaaggtc gtgaagaagt
    46201 gatctctacg atcaagaaga tcaaagaaga aagtcaattg accgttatat ctatcactca
    46261 tgatattgat gaagcagcta atgccaatcg gatactagtg atgagacaag gcgaacttgt
    46321 ccgtgaaggt acaccaaaag aaattttttc tgctggtcct gaactgatcg acttaggtct
    46381 agatctacca tttcctgaaa aactgaagag cgcactgaaa gaacgtgggg ttgatgtgcc
    46441 cagtgaatat atgacagaag aaaggatggt ggattggtta tggacatccg ttttgaacaa
    46501 gtagacttca cttatcagcc gaatacacca tttgaacaaa gagccttatt tgacatcaat
    46561 atgacgatca aagaaaacag ttatactgca ttagtagggc ataccggaag cgggaaatca
    46621 accttacttc agcatttgaa tgcgcttgtt aagccaacaa gcggtacagt ccatattgga
    46681 gaacgagata ttcagccgga tacggataat aagaatttaa agcccatccg aaaaaaagtt
    46741 ggcatcgtct ttcagtttcc agaagcacag ctattcgaag aaacggtagc aaaagacatt
    46801 gctttcggtc ctaaaaactt tggtgtcagc gaagaagaag cactagtcct agcaaaagaa
    46861 acattagaac aagttgggct ggatgaaagc tatttggaac gttcgccatt tgaactttca
    46921 ggagggcaaa tgcgtagagt agcaatcgct ggtgtgcttg ccatgaggcc ggaagtactt
    46981 gtattggatg aaccaacggc aggacttgat ccccagggca gaaaagaaat gatggagatg
    47041 ttttggcgtc ttcataagga acagcagatc actattgtat tagttacgca tttaatggat
    47101 gatgtagcca attttgcaga ttatgtctat gtgttggaaa agggacgaat cgttaatagc
    47161 ggggagccgc aagaggtctt tcaaaacatt gaatggctaa aagaaaaaca actaggcgta
    47221 cctactgcca ccgagtttgc agaagaatta atggctaaag ggatgaactt tgctaccttg
    47281 cctttgacag ctgaagaatt agcagacgct atcgtccatt atgctggagg aaatgcccat
    47341 gatgaataaa ttgatatttg gtcgttatat gcctggagat tccttgatcc atcgattgga
    47401 tccccgagct aaattattag ccagttttta ttttatcgga atcatttttt tagcaaataa
    47461 ttgggaaacg taccttttgt tggcattttt cacattactt tctgtcttct tgtcaaaagt
    47521 agatttgaaa ttttttatcc gaggcattcg cccattgatc tggctaatcc tcttcactgt
    47581 agctttgcag gtcttgttta caagtggcgg agaaacttat tggagttggg gtgttttcca
    47641 tatcactgaa tttggtgtga tgaacggcct ctttattttc tgtcgattcg tgttgatcat
    47701 ttttatgtcg actctactca cgcttactac accgcctttg gaattatcgg atgcgattga
    47761 gtacttgctt cgtccattga aagccgtacg gttcccagtc cacgaaattt cattgatgct
    47821 gtcgattgct cttcgttttg tgcctacatt gatggacgaa acagaaaaga tcatgaacgc
    47881 tcagcgcgct cgcggtgttg attttggtga aggaaaccta gttcagaaaa tgaaagcagt
    47941 cattcctttg ctgattcctt tatttgtcag cagcttcaac cgtgcggaag atcttgcgac
    48001 tgctatggaa gcaagaggct acaaaggtgg ggaaggaaga acgaaatatc gtgtattgca
    48061 ttggcataat agagacacga tggttatcat tgcttttgta ttattaactg tgctactgat
    48121 ctttttaaga ggataaacgt tcagtgggcc gctatctatt cttttcttgc tgatctgttt
    48181 gcaagaaagg atgcaagcag tgtatgacaa gaaatattag ggtctgtggc agactaaggt
    48241 cacaggcctc tttcttttat ctgaaaagaa agaacgaaaa aattttatag aaaaatcatt
    48301 attccagata accttttagg aacaaaggag agaaaaacat ggtacgttac aaagcaatca
    48361 ttgcgtacga cggaacaaat tttaatggat tccaaaaaca gccaaatggg cgtactgttc
    48421 aagaagaagt agaaaaaaca ttacaaaaaa tggcaaatgg aaaagaaatc acggtctttg
    48481 gttcgggaag gacagatgcc ggagtacatg cgatcgggca agtaatccat tttgattatc
    48541 cagaggagcg tccgttagaa cgaatgcgtt tcgcgctaga tacccagtca ccagaggata
    48601 ttgctgtaag acaagtagaa attgtttcag aagacttcca cgcaagatat ttggtcaaag
    48661 aaaagacgta tcaatttcga gtggatatag ggaaaccacg cagtcctttt cgacgccatt
    48721 atgcaagtta ttttccttac ccacttgatt tggaaaaaat tcagcgggcg cttcctgatt
    48781 tattagggac tcacgatttc acctcttttt gtgcatcagg aagctcgata gaggataaaa
    48841 tacgtacgat ctacgaggct aagatggagg taaatgaaac aaaagacgaa ttgttgttta
    48901 catttagggg aaatggcttc ttgtataaga tgatacggat cttagtagga acgcttttga
    48961 aaattggcaa tggccgattg cctgaagata gtatcccaga tattattgcg aaaaaagatc
    49021 gtaatgcagc aggacctaca gcacaccctg aaggacttta tttgtatgaa gtgaaatatg
    49081 aataagaggt tatgatagaa gtggtcagct tcaagaaata agaaggtatt tacgaaaatt
    49141 acttctcaaa attttgcaaa atttcggctt attttcgaag aagctacttc tggaacaccg
    49201 tttaagaaag aggtcgtgag cctgtcattt aactctgagt cacaaagagc aatttcaaaa
    49261 aacagcttct catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc
    49321 atctttttgt tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc
    49381 cttggtgcgg acagtctgaa caggttccat cgtttcttta ttttctacgt cttcttctgt
    49441 gtgtgtttcg tggttgttct tctattgctg gatcaatcgt gccataaaag gggcgattgc
    49501 ggtcaaggta ccagacataa agaataaaca atgcaataca taggacaaaa aggattgcac
    49561 ctatcgtaaa tccttcaggc aagtaactga aagtgacagt atgtttacct gctggaactt
    49621 ttatcatcaa gaatgcgtct ttgaaattgc tgaccttgac tggtttccca tcaattttag
    49681 ctttccatcc tttgtcataa ggaatagttg tcaccaacat ggaatcttca gcggtattta
    49741 cagtcccaga agcttttctg ccagtggctt ccatttcgac acctttttct ttgatctgat
    49801 tcattgcggc ttgataggct acaacatcta gaccaacgac tttaggctcc atgaaactta
    49861 tttctttcgt cccataaaaa cttgcagtaa atgtcactgt tgtctcttga ggataatagc
    49921 caagatcata gtattgacca gaaatgttga tttgcgtttt tcgcgatgta ccattgacag
    49981 tgatcgtcgc actagaactt tctaattgcg caaaattggt tgggaacaaa cttaagtaag
    50041 cttgtgtatt tgcaggcaca tggacttccc aagtgagctc ttttggctgg ttatctgctg
    50101 tttctgagta agtgacgcca gtcgttgtct ttgtgatcgt cgtattcaac tgattcttca
    50161 aagtaggtgt atagaatgta aaatactgtt catttagacc agacaatgta ttgatcaagt
    50221 ttgtctgact ggtcaaatta tctgtcactg gctgctcaac atcattaacg gacaacggtg
    50281 cagtaaatgc tagtggcaat gcattgacat tctgatacag tgtatagtcg ccgctttgac
    50341 cagcttggcg gaagccatat ttactgaacg tgctttcgtt tttagaaatg ttatatttga
    50401 ttcctgtaaa cccatccatc agcaaagtat tattgttata acggatattc aaatttgtcc
    50461 ctcttgaacg gaaacctaat ttatccaggt aagaggaaga attacgattt cttatagaag
    50521 aaaacaaact gataccactg taaccatagt tgatcgaatc gtttgcagat actggatcca
    50581 gattttccaa gcggtaaaac gagtcggaat ctttttttgt ttcatttaca agagctttca
    50641 agtcaggata aggatcagta tataaactgc gggaagcata attccaatca tcaagaatgc
    50701 catggatcat actgttcgta ttgaccagtg cttcagcaga catgatcaat aataacaata
    50761 tactcagatg attgaatgaa agttttttat gctgataaaa tcccacagca aaagcataaa
    50821 tccctaagaa aaccactgtc aatacaaagg aagtcatcgt cacataggtg tagcttcctt
    50881 caggtttgat gccccatgcc accgcaaaga gagcagctac gaccaaaatg attcctaaca
    50941 acagcccacc atcgtcttgt tctatctttt cccatccttt tcctgcaagc aggagcacta
    51001 agaaagagaa cagataggca taacggaata aaaacatatt cggtgcatgc ataccatgcc
    51061 agaacaaatt caatggaaca agataaaaac ttgcgataag tatggcgaaa agactgccgt
    51121 acaaaaattt atttttcaac ggtactttcc gactggcaaa ataaaacaga cagaggacta
    51181 atggtagcag acctgcgtaa acgaacggaa tcgatccgta ttttgtcgtg tcataaacac
    51241 caatcatatt tttcatgatt agatccagat aagaagtcgc ttctgttttc aacgtagtga
    51301 tctgactcag tgcctcgcca tttgaccgaa gatccagcac tgctggcaat acaatgatca
    51361 ttgaagcgcc gcctgccagt aaagaagtga taccataagg aacaatcgtt tttttatatt
    51421 ctgaccagtt tgtcaataga cgggcgataa aatataagaa agaaaatacg ccaatcataa
    51481 aacccatata aaaactggat aaaaacaaga gtaaataact gataaataaa agtttcggcc
    51541 gtttaagatc cataacacga tgaatcccca aaatcactaa tggaagataa acaaatgcat
    51601 ccagccacat gatgatctcc gaatgtgcag tgataaatga gatcaatgcg taactgacgc
    51661 taagtgcaac atgcccccag cgaggaatct tgaacgtacg tgcaagaaac caaaaagcca
    51721 atccggcaca gccgacctta agcaaagtca gaacatacag tgcatctggc atcatctggt
    51781 ttggaaaaaa gaacaccagt ggcgtgaaga tcccgcctag atagtaagaa attaaagata
    51841 aataattcaa tcctagagaa gcattccatg tataaaaaat actttgcttt ccaagaagaa
    51901 catttcggaa gctggcatga aaattagaaa actgtgaaaa ggcatcactt gccaaaatac
    51961 ttctgctgct tccaggatag attccgatac ttagataaac aagtgctaaa atcaaaaacg
    52021 gaatcaggaa actagctgct gcgtagcgtc cgttttctct aaagaatgac tttaaatttt
    52081 ttttcatatt tattttccac caaatttcta tgaagttgta ttcagtttat catatccttg
    52141 tttttctctg cttaaaaaga gtctagtttt cacaaaaaaa taaaatttag aataaataac
    52201 ttcataattt gttcgtataa caaaaataaa cgcaaaaaaa gggtaggaat caaaagtccc
    52261 acccttaaaa atttttatta aataaaaaac cgttcactat ctgaacggtc caagtatcat
    52321 tcaattaaac gcgttcaact tttcctgatt tcaaagcacg agttgacacc caaacttttt
    52381 taggttttcc gtcgaccata acgcgaactt tttgtaagtt aggtttaaca gtacgttttg
    52441 ttgagttcat agcgtgtgaa cggttgtttc cactttttgt cttgcgacct gtaaagtaac
    52501 aaacttttgc catggtaatt tcctcctttg ccttgatttg gagcaataga ataattcagc
    52561 tcataccaga ctaacatatc atatagaatg ggaatttgca agtacatttt catagataca
    52621 attgacaatt gagaagaata attgtaaatt aaacaaggtt atacctgaaa ttttgcaagg
    52681 tttttgagta ctttgggtaa ctgcctttta tttcaagttg cgctatgata aaatatgata
    52741 gaagaaaaat gggagttttt tacccgttaa ggaggctcat tcatggctgt aaaaattcaa
    52801 acgtcagctg gaaccattga aattaccaat gatgtaattg caacagttgt tggtggcgcc
    52861 gcgacagatg tgttcggtgt tgtaggaatg gccagcaaaa atcaaattaa agataatatt
    52921 actgagattt tgcgtaaaga aaattactca agaggagtag ttgtccgcca agaagataat
    52981 ggtattgctg tagatgttta tacgattatc agctatggta cgaaaatctc tgaagtttcc
    53041 cgcaacgtcc aagaaaaagt gaaatacaat ctagaggcat tattaggcgt aactgccaat
    53101 tcagttaatg tctttgtaca aggtgttcgt gtactgccag actaggcagg agactggctg
    53161 gtaactcagc agtcgatctg aaggaggatt atctaggtga gtgtaacaga aataagtgca
    53221 agccagttcc aggaaatggt ccaggcaggt gcgaatcgtc tgcaagtaaa tgcagaatac
    53281 gtcaattcat taaatgtatt ccctgtgcca gatggcgata cgggaacaaa tatgaatcta
    53341 tctatgacta gtggagctaa ggcagtagta gattcaacct cagaaaaagt aggagaatta
    53401 gcagcaatgc tttcaaaagg attgctgatg ggtgcgcgcg gaaattccgg cgttattttg
    53461 tctcaattgt ttcgtggatt ttctaagcaa attccagatg ttgtctcatt aaatgcttct
    53521 gatcttgctg cagccttcac tcatggagtt gaaactgcgt ataaagcagt aatgaaacca
    53581 gtagaaggaa cgattttgac agtagctaga gaagcagcga aagctggaga aaagaaagca
    53641 aaaagtactg atgatgtcgt tgaagtaatg acagctgttg taaaaggagc aaagcgtgct
    53701 ttagctaaaa ctccagactt gcttccagtc ctaaaagaag tcggtgtcgt agacagtgga
    53761 gggcaaggac tgctgtttgt ttatgagggc tttttaagtg cattgaatgg agaattccaa
    53821 gcggatgaaa catatgaacc ttctccagca gaaatggatg atatggtcaa tgcagaacat
    53881 catcgcagtg tccaaggtca aatggcgaca gaagatatcc attttggtta ctgtacagaa
    53941 atcatggtaa aaatcggaga aggacctaca gtcgatagta cattcgatta cgaagaattc
    54001 cgtaactatt tagatggtat aggagattct ttacttgtgg tcaatgatga cgagatcatc
    54061 aaagtccacg tgcatacaga aaacccagga gaagtcttga attatggaca aaaattcggt
    54121 tcattagtca aaatcaaagt cgacaacatg cgcttgcagc atgagacgat tttggaacac
    54181 gatgaagaag tgaacgagtt tgcgaaaaaa gaaataccac gtatcccgta tggtatcgta
    54241 gcgatcgctg ctggtaaagg cgtccaagag ctgtttgaaa gtttaggcgc taattatgtt
    54301 atcagtggtg gacaaacaat gaatccaagt acggaagaca ttgttaaagc gattcaagaa
    54361 gtaaacgcag ataaagtgat tgtcttgcca aacaataaga acatcttcat ggcagctgat
    54421 caagcagcag aagtagcaga tatcccagta gcagttgttc cttcaagaac gatttcccaa
    54481 ggattgacag ctatgctttc attcaatgat caagcttctt tagaagaaaa caaagaaacg
    54541 atgacagaaa tgttgtctag cgttgtgagc ggtcaagtca ctcacgcgat cagagatacc
    54601 tcaattgacg gtgtagagat caaagaagga gactttttgg gcatgatcga tggaaaaatc
    54661 ctgatctcta acccagatat cacagcaaca gcgttaagta cactagaaca aatgatcaat
    54721 gaggacacag agatcgtaac gatcttggca ggtgatgaag gaacagttga acaagcaaat
    54781 gaatttgctg agaaactaac agaaaaacat cctgatttgg aaatcgagat ccaccaagga
    54841 gatcagcctg tctatcctta tctattttct gctgaataat ttctgtgtca gaatatcttt
    54901 ctaacacagt attcattcat aaaaggcctt cggttagtga tcaggtatga tcgctgacca
    54961 agtccttttt ttgttaaagg agggaggaaa aatttatgcg ttctttagat gatccaatca
    55021 ctatgctggc aggagtcgga gaaaaaagag cagctagtct tgccagcttg ggcatccaaa
    55081 cgattgaaga cttactgact tattatcctt ttcgctacga agatattcag gaaagaaatc
    55141 taaacgagat ccaggatcaa gaaaaggtta ctttgaaagg aatcgtagtc tcgcctcctg
    55201 tgatgaatcg atttggttat aaaaaaagcc gattgcaatt tcgtatgatg caagaacatg
    55261 atgtgttcaa cgtttctttt tttaatcaac cttatctaaa agaaaaagtc attttatcgg
    55321 aggaaatcgc cgtatacggt aaatgggatg caaagcgtaa agccttgaac gggatgaaga
    55381 ttttaggttc tcaaacaatg gatgactttt cgccgatata tcacgtcaac aaatcaattc
    55441 gtcaaacgac attagttgat ctaatcaaaa aagggtttca agaatacggc acattgattg
    55501 aagaaaatct gccaaacaac cttgtggaga aatatcgact gcttgaccga gcttctgctg
    55561 taagaagtat gcattttcca aaagaccacg aagaaaacca tcaagccaaa cgacgtgtcg
    55621 tttttgaaga gttcttttta tttcaaatgc gtcttcaagg attgaaaaaa gcagaaaaag
    55681 cagaaacgaa tggtttggag atcctttatg atgtccaaaa attgaaacaa tttactcaaa
    55741 agctaccttt tgaactgaca aatgcacaaa aacgtgtaac gaatgaaatc tgtcgggatc
    55801 ttcgcagtcc gcagcatatg cagcgacttt tgcagggaga tgtaggtagc ggaaaaacag
    55861 tggttgccgc gattgcgtta tacgctaccg ttacagcagg tttccaaggt gcgttgatgg
    55921 tgcctacaga aatcttggca caacaacata tggaaagctt gcaacagctg tttgatccca
    55981 atgaagtaac catcgcattg attacggggt caacgaaagc aaaagaacga cgtgagctcc
    56041 ttgaaaaact agagcaaggg gaaattaacg tcgtgatcgg cacacatgca ttgatccaag
    56101 atggagtcga atttcagaat ttaggtctag ttattacgga tgagcagcac cgttttggcg
    56161 tgaaccagcg gaaagtactt cgtgaaaaag gctggcgacc agatgtctta tttatgacag
    56221 cgactccgat tcctagaaca ttagctatta cagcatatgg tgagatggat gtatctatca
    56281 ttgatgaact tccagctgga cgtatcccga tcgaaacacg ctgggtaaga acacctcaat
    56341 tggacagtgt actggattgg acgaaaaaag aactggcaag aggacatcaa atgtatgtca
    56401 tctgtccgct gattgaagaa tcagaagcat tagatgtaaa aaatgcagtg gaaatctatg
    56461 aaaaacttcg tgaactattt gcaccaaaat atgaagttgg cttgttacat ggtaaaatga
    56521 agaatcagga aaaagaagta atcatggaag ccttcaaaga caaccagatg cagatattag
    56581 tttcgactac tgtaattgaa gtaggggtaa acgtgccgaa cgcgaccgtc atgctgatca
    56641 tggatgcgga tcgatttgga ttggcacagc tgcaccaact tcgtggacgt gttggacgcg
    56701 gaagtgatgc ttcctactgt atcttagttg ctaatcctaa aaatgaacta ggtgtggaac
    56761 ggatgaaaat catgacagag accaccaatg gttttgtact aagcgaaaaa gatctggaat
    56821 tacgtggtcc tggtgaagta tttggcttcc gtcaatctgg tctgcctcaa tttgcgattg
    56881 ctgacttggt gacggatgga aatgttttgg aggtagccag agaagaggct gcagcccttt
    56941 ggcaaataaa ggattggcag atgcttcctg agtatcagcc tttagcgcaa agcctccaaa
    57001 tagaaaatca ggataatcgt tatttcgatt agcagactgt gctatacttt atactgatga
    57061 cggaaaaagg agtggaaaca atgaaaattg ccgtagatgc aatgggcgga gatcacgcac
    57121 ctcaagcaat tgtagaaggc gtggctttag cgcagcaaga ttttccagaa gtagaattct
    57181 tactttacgg aaaagaagca gaaatcaaga aatacttaac aaatgaaaaa aacatcacga
    57241 ttatccatac agacgaaaaa atcaatagtg atgatgagcc agtaaaagca attcgacgaa
    57301 aaaagactgc atcaatggtc cttgctgcac aagcagtgaa aaacggtgaa gcagatgctg
    57361 tattttcagc agggaataca ggcgcgctac tagcagcagg gttgttcatc gtaggacgta
    57421 tcaaaaatat cgaacgccct ggcttgatgt ctaccttgcc agtagtaggg aaagaaggtg
    57481 ccggtttcga tatgctggat cttggcgcta acgcagaaaa caaaccagaa catttgttgc
    57541 aatacggtat tttaggttct ttttatgcac gtaaagtccg aggtatcgga cgtcctcgtg
    57601 tcgcactctt aaacaacgga acagaagcaa caaaaggtag tgaagtgacg aaaaaagcct
    57661 atgaactcct tcagaatgaa acaagcttga attttattgg aaacgtagaa gctcgtgagc
    57721 tactcaatgg tgtggctgat gtagtggtca cagatggatt tacaggcaac gctgttttga
    57781 aatctattga aggaacagca atgaatatga tgaatctatt aaaatctgct attctaaatg
    57841 aagggatcaa aggaaaaatg ggcgctatgc ttttaaaaga cggcttacgt tctttgaaag
    57901 cagaaatgga ttattccaaa catggcggtg ccgttttgtt tggcttgaaa gcaccagtca
    57961 ttaaaactca tggagcaaca ggccccgatg ctgttcgcta tacgatccgc caaatccaca
    58021 caatgcttga gacagatgta gttggacaat tagtcgaaca atttgaaaaa agcgaagaat
    58081 agtatttgga tatctgaagc gatccgttcc attgaaaaaa aggtggacat tcctgaaaaa
    58141 tgccagtaaa attagccatg gtgtaggtaa ttgacaagtg tatgattctt ggaggtgaaa
    58201 aagttgactc gcgaagaagt atttaacaaa gtagcgaaaa ttatttcaaa tcattttgag
    58261 atagataccg ataaagtgac ggatgaattg aacatcaaag atgatttaaa agctgattca
    58321 attagtatta tggaattcgt tttagagctt gaagatgaat tcggtacgga aatttcagat
    58381 gaagacgctg aacaaattga aacagtcggt ggcgcagtag attatatcag cagccatctt
    58441 aaataatttc aaataaaagc aaagaaggat aaaaagctgc atgcagcttt ttatccttct
    58501 ttttttaatc tttttgacac gtaaaagtca tttttctgat aattctggcg ataaacagaa
    58561 attatgttgc aaagtaaagc ggttttctat ataattatta ataattcatt acacaaagat
    58621 aagaataacc tttgttataa aacgatttat tctgtgtaat gtcctttttt attaagaaaa
    58681 acttccattt aggaagcaga gaggggtatt cgattgtccg ataaccaatt attagaagtt
    58741 cagaacctac atacaggatt ccgactcaaa gatgactatt acgatgcagt agatgacgtt
    58801 tcatttactt tagacaaaaa cgagatttta gcaatcgttg gggaatctgg gtgcgggaaa
    58861 agtaccttgg ctactacgat tatgggatta cttgatccta ataacacaaa aattacaggt
    58921 gagattttat ataacgatct gaatttaatc gacctgaacg aaacgctcta taataaaatc
    58981 cgcggaaatg atatcggaat gattttccaa gatccgttgt ctgcattaaa tcctctcatg
    59041 agaatcgaag accagatcaa agaaggactt tcctatcaca caaagatgaa tgcagaacag
    59101 cgtcaagctc gtgcactaga attgctagaa caagtaggga ttcctaatcc tgcgagagtt
    59161 ggacgccaat atccccatga actatcaggc ggtatgagac aacgtgtcat catcgcaatc
    59221 gcaatcgcct gcaaacctcc aatcgtcatt gcagatgaac cgacgacagc cctagatgta
    59281 accatccaag cacagattct tgatttactg aaagaccttc aggaagaaac aaaaacaggg
    59341 atcatcttga tcactcatga cttaggagtc gtagcagaaa tggctgatcg agtggcagtg
    59401 atgtatggcg gacagttcgt tgaagtagca ggtgtaaaag aactgtttga tcatcctaag
    59461 catccttata cacgctcttt actgaactct ataccacaag aaggaaatca tgatgcagaa
    59521 ctccatgtga tcgaaggtgt cgttccttct ctgaaaaaca tgcctcgtaa aggttgtcgg
    59581 tttgcaccac gtattccatg gataccagca agcgatcatg aagaagagcc tatccttcat
    59641 gaagtcgcac cgaaccactt ggtacgttgc tcctgctata agcatttcca ctttagagac
    59701 gaaaaaggag aggtgtagat gacagaatta atcacaatca aagacctgaa agttcattac
    59761 cctattcgca gtggattctt caatcgagta acggatcatg tatatgctgt agatggtgtg
    59821 gattttatta tcgaaaaagg aaagacatat ggtttagtgg gagagtctgg ctctggaaaa
    59881 tctactacgg gaaaagccgt tgtgggatta gaaaaggtaa cagccggaca aatcatgtat
    59941 gaaggaaaag atgtaacgaa gcgaagcaac cgcaaaaaaa tgggttataa caaggatgtg
    60001 cagatgatct tccaagattc aatgtccagt ttgaatccta aaaagcgagt gttggatatc
    60061 attgctgaac ccatccgaaa ttttgaacgg ttaagcgatc aagaagaaaa gaaaaaggta
    60121 aaaggactgc tagatatcgt tgggatgccg gaagatgcgc tatataaata tcctcatgaa
    60181 ttttcaggcg gacaacgtca acgtctagga gtagcccgtg ctgttgctac caatccaaaa
    60241 ctgatcgtag ccgatgaacc tgtatctgct ctggatctat ctgttcaagc gcaagtattg
    60301 aatttcatga aacgaatcca gcaagaatac ggcctcagct atttattcat ttcacatgat
    60361 ttaggtgtag taaaacacat gtgcgacaat atcgcaatta tgtacaaagg tcgatttgta
    60421 gaaatcggta caagagaaga catttataat gacccgcgac atatctatac gaaacgtctg
    60481 ctttcagcta ttccgcaaat cgatgtagaa aatagggaaa gccacaaaga aaatcgacga
    60541 agagtagaac aagagtatat ccaaaaccaa aaagaatact atgatgcgac tggtcgagtc
    60601 tacgatttgc gtacgatcac aactacacac aaagtggcgt tgaaagatgg aggtgcaagc
    60661 taatgtggaa aacgattctg cgacgtgttt tattgatgat cccgcaagtt attattttaa
    60721 gtgttctgat cttcttatta gcccaagcga tgccggggga tccatttacc ggtttgatca
    60781 atccaaatca ggatccggca gtgatcgaac agatgcgaca agcagctggc ttgaatgacc
    60841 catggtatgt ccagtacttc cgttggatcg gaaatgcttt gcaaggcgat tttggtcaaa
    60901 gtttcttata caaacgctct gttgctgact tgatcggcga acggatcatc aacactttat
    60961 atctatcgat cttgacagtt gtccttactt atttgattgc tgtgcctctg gggatgcttg
    61021 ctggccggta tcaaaattca atcttggata agattgtcgt aatctacaac ttctttagtt
    61081 ttgctgttcc tttatttatc ttcggcttga tcatgctatt tgtttttggt tatcgtttag
    61141 gctggttccc aacaagtgga tcacaaacac taggtttgca aggtggattt atcactcaat
    61201 ggatagaccg tttgaaatat attctgttac catcaattac ccaagcattt ttggcgactg
    61261 ccgtcacaat ccaatatctg cgaagtgaag taatcgattc gaaatcgctc gattttgtca
    61321 gaacagcccg ttccaaaggg gtaccgacga ataaagtatt cagtcgacat attttccgaa
    61381 atgcagcgtt gccgatggct tctcaaatgg ggtatgaaat cacttcgttg attgctggtt
    61441 ctgtagttat cgaaaagatt tttggttatc cgggagtcgg aaaactattt attgattcca
    61501 tcggccaacg ggactatacc gtgatcacat ccttagtatt gattttagga atcgcgacgc
    61561 tagtggggac attactttca gatatcatca tgagtatcgt tgacccgcgt attcggattc
    61621 aataaaacca atcagaaagg agaatggatc gatgagtgaa aaaaacaata cagcagttca
    61681 agaaagtatt cctcctatgg ggatacgaat gattgctcga gaatttaaaa aagataaaat
    61741 tgctattttt tcattaggtt tgctagtggt tttattatta gtgatcttta tcggtgcgat
    61801 gctgaccgat caagacaaag tgatgtatgt tagtatcttc gacaaatacg ctgcaccagg
    61861 aacagtttcg acacaaggac aaaagttcat tctgggagca gatgaaggcg gacgtgatgt
    61921 attaggacaa ttgatcatag gtgctagaaa ctctgttacg atcggatttg cgatcacgat
    61981 ccttacttcg atcatcgggg ttggattagg gatcatctct ggctactacg gagggatcat
    62041 tgacaacatc ttgatgcgga tcgttgattt tatcatgatt ctaccgatca tgctgatcat
    62101 tatcgtcttc gtatcgatta tttccagata caatgtctgg tcctttatat tcatcatgag
    62161 tgcattttat tgggtagcta aagcccgatt attccgaagc aagacattat ctgaagcaag
    62221 aagagattat gtcagtgcct caaaaacaat gggaaccaat gattttaaaa tcatgttccg
    62281 cgaaatcatg ccgaatctaa gttcattaat cattactaat ttgacgatga actttgcggc
    62341 aaacatcggt atcgagacaa ctttgacttt cttaggtttc ggcttgccgg caaatgtacc
    62401 tagtttaggt acattgatcg gttatgcaag taacggagaa gtcttagtga atcggcaatg
    62461 gatctggtta cccgcatcaa tccttatttt agttttgatg ttgagtatca attatgttgg
    62521 acaagcattc aagcgttctg cagatgcgcg ccaacggtta ggctagtata gaagcgaagg
    62581 gggaaatagg aatgaagaaa acgatttttg gatttgcagc gctgatgtct gctgtcgttc
    62641 ttgcagcatg cgggggcgga ggtacagata cctctggaaa caactctgga ggcaacggca
    62701 ataacaaaga ggaattaact tttccaattg caacaaaaaa taatgatgat gcaatcgaag
    62761 acggcgaatt agaagctgcg gtcgcaacgg acagtcagtt taaaggattg ttccagtggg
    62821 agttttacca agattcatat gatgcagctt ttatggctcc ttctcatgaa ccgctatttg
    62881 caaacgatga cgatttcaga atcacagacg acggagctgc aacgcttgat ctagatgaag
    62941 atacgaaaaa agcgacaatc aaagtaaaag acaacgtcaa atggtcagat ggtgaagatg
    63001 taacggcgga cgatgtgatt ttcccttacg aaatcattgg gaataaagat tacactggta
    63061 tccgttatga cgacactttc cgtaacatcg taggtatgga agaatatcat gatggaagtg
    63121 ccgacacaat ctccggaatc aaaaaaatag acgacaaaac agttgaaatc gaatataaag
    63181 aagtaaaccc aagcatgctt caatcgggtg gtggtatctg gtcatatgca gcaccaaaac
    63241 atacgttaga aggtgtagca atcaaagata tggaatcaag cgatcaagta cgtaaaaatc
    63301 cagtgacttt tggcccttat tacatgagta atatcgttgc aggagaatca gtagaatact
    63361 tgccaaacga gcactactgg aatggtacgc ctaaattgaa aaagatcacg atgaaatctg
    63421 taccgatggc aagtgcaact gaagcattga actctaaatt atatgatatg attttccaaa
    63481 tgccaacaga tacttacgat acctataaag aaattgctgg ctatacaaac ttaggccgtg
    63541 aacaaacttc ttatacttat ctaggattca agttaggtaa atggaatgca gatacaaaga
    63601 gtgtggaata caatccagat tcaaaaatgg ctgataaatc attacgtcaa gcaatgggct
    63661 atgcattaga taataatgca gtaggtgaac gtttctatgc aggtttgaga agcaatgcga
    63721 cttcattgat tcctccagta ttccagtcat accatgatga tgagatgaaa ggattcacac
    63781 aagatctaga caaagcgaaa aaactattag atgatgctgg ctacaaagat gtggatgacg
    63841 atggtttaag agaagacaaa gatggaaata aactaacaat caactttgct tcgatgtccg
    63901 gtggggaaac agcgcaacca ttggcagatt actatatcca acaatggaaa gaaattggtt
    63961 tggatgtcca atacacaaca ggtcgtctga tcgaattcaa ttctttctat gataaattag
    64021 aaaacgatga tcctgaaatt gatgtttacc aagctgcttg gaatacagga actgatccaa
    64081 atccaagtgg actatgggga ccaaatgctg cgttcaacta cactcgttat gaatcagaag
    64141 aaaatacaaa attgatcaac gatatcagtt caagcaaagc atttgatgaa gagtaccaaa
    64201 aagaagcata tcaaaaatgg caacaatatg catttgaaga agcatttgcg attccaacgt
    64261 tgttccgtaa tgaagtattg ccagtcaacg accgtgtcaa agactgggat tggtcttatg
    64321 atgtaccaaa cccatgggca aatgtttctg ttacagcaga ttcacgttca taatcactaa
    64381 aaatgaccga aaaagggcga tgtccttttt cggttttttg atatttttct gtttatttct
    64441 ctaatattca ggtcaaggcg ctgatttcat gacttctcca ataaacggtg ttcaaagtcc
    64501 agtttctcgg tattaagtca aatttatgca aaaatatgga aagccatttt cacaaaattt
    64561 tttcttcata ctcgaaacta aacgaatttt tcacaacttc tcgtcaatca ctaggattat
    64621 taaagcttta cttacctttt gaccgaacca tttcaaattt gacaaaaaac cagtataata
    64681 aggaagtatc gaaaaaatat ccataaaagg aatgtggaaa atggacaacc agctgacaaa
    64741 agaactaaaa gaaaactata acatcgtttt tcacgatcta aatttgcttg aacaagcttt
    64801 tacccattca tcctatgtga atgagcatcg caatctgcaa ttatcggata atgagcgact
    64861 tgaattttta ggagatgccg ttttagaact gatggtttct cagtatttat tccgtttata
    64921 tcctcatttg ccagaaggaa aattgacaaa aacacgagct gcgatcgttc gcgaagacag
    64981 cttgtcgaaa tttgccaaag aatgtcactt tgatcaatat gttttgttgg gcaagggaga
    65041 agagaattca ggaggacgta cgcgaccagc attgctttgc gacctattcg aagctttttt
    65101 aggcgcgtta tatcttgacc agggattcga cacgacccat gcattcatcg aaaaagtgat
    65161 ttttcctaaa gtcaaagcag gtgctttttc acatgagatg gatcataaaa caaaactaca
    65221 agaagtcttg caaaaatcag gtgatgtatc aatcgaatac cgattgatca atgaagaagg
    65281 tccagctcat gaacgagtat tttggatcga agtttatgta gatgatcaat tgattggcac
    65341 tggacaaggg aaatcgaaaa aattagcaga acaagctgcg gcggaaaatg cattggcagc
    65401 actgtaaaag taagtgaggg aaagctttgt atttgaaacg aattgaaata gccggtttta
    65461 aatcatttgc agacaagaca gtcattgatt ttgaaaatag cgtcacagca gtggttggac
    65521 caaatggcag cggaaaaagc aatattacag aggctatccg ctgggtatta ggagaacaat
    65581 ctgctaaaag tctgcgaggc ggaaaaatgc cggatatcat ctttgccggt tccgataccc
    65641 gtaagcagct gaatattgca gaagtcacag tgattttaga caatagtgat cattatctgc
    65701 cattggagta caatgagatc agtgtaaccc gccgttatcg acggactggg gaaagcgagt
    65761 ttttcatcaa taaacaaagc tgcagattaa aagatatcca agaattgttc ttagattctg
    65821 gattaggaaa agaatcgttc tcaatcattt ctcaaggaaa agtagaagcg attttcagta
    65881 gtaaaccgga agaccgtcgt gggatctttg aagaagcagc tggtgtcttg aaatacaagc
    65941 agcggaaaaa gaaagcagaa cagaagcttt ttgaaacaga agacaacctc agccgcgtcc
    66001 aagacatcat ccacgaattg gaagaacagt taactccttt ggccgcccag agtgaggcag
    66061 caaaggagtt tttacggcta aaagaaacac tgactcaaac cgatgtctct ttgatggttg
    66121 ctgaaatcaa gacagcaaaa aaagattggg acaacaaaca agcacagctt gcgaaattca
    66181 atctagaatt aggcaaacta tctgagtcga tccaagaaca agaatccatt ttggcgaagc
    66241 agcgtaaaga aaatgcgcaa gccgatcgtc tgatcgaaaa aaatcagcaa gtattattag
    66301 atctttcgga aaaactgaag cagacagaag gacaaaaaga tgttttgcag gagcggacaa
    66361 agcatacaca aaaaagctcg caagaatatc aaacttcatt agcagaagca caaaaaaagg
    66421 ttaaacattt tgaaaagctt caagaaagct tgatgaaagc agcagcagaa aaagaaacag
    66481 agatccaaaa agctgaagca aatctcataa aaacacagca agaattagaa aaataccaaa
    66541 aatcaacgaa agaattattg gcagaattaa gagatcaata tgttgatttg atgcaagaac
    66601 aagcagctgt aggaaacgaa ctgaagtatc tagaacgtca atatatacaa gaaacagcaa
    66661 aaagcaagca gacgttagcc aagcaatcgg aagtagaagc atcagtagac cgattgatct
    66721 tacaaaaaga agaattgaca caaaagcagg cgcagctaaa atcatcttta actgaaacaa
    66781 aagagaagtt agaaatgatc caacaaaacg ggaaaaagtt ccaagaagca ttagcaaaag
    66841 aacagcctaa aatgtatcaa ttaatgaatc aagtccagca gctacgtgct cgtaagaaaa
    66901 gccttcaaga aatccaagaa aactattttg gtttttacca aggggttcga ttggtcttgc
    66961 agcataaaca gcagctttcg ggtattgtcg gagcagtggc tgaactgatc gatgttcctg
    67021 cagatttcac gttagctatc gaaacagctt taggtggggc agcccagcat gtcatcgttg
    67081 aaaatgaaaa agatgctcgg caagccatca cgtatttgaa acagcaaaga ggaggaagag
    67141 caacattcct tccactgacg acaatcaaac caagacaatt accggctcat atattgacac
    67201 aagcagcagc tgtagaaggg tttataggga ttgccagtga acaagtcagt tatcccgatc
    67261 aaatccaaac tgtggttcaa aacctgctag gaacgatcct tttagccaaa gacttaacta
    67321 gtgccaatgc aatcgcgcaa acgatccgct atcaatatcg agtggtttcc ttagaaggtg
    67381 atgtgatgaa tgccggagga tccatgacag gtggagcgaa taaacgagga aaccaaggca
    67441 gtttgtttgt acaaaatcaa gaattgaaac agttgactag tgaatttgaa gaagcagata
    67501 aacaactcca agcacaagaa aaaaaagttc aggagctgca acaagaaaca gctcgtttag
    67561 ccgaagaaca agaagttttg cgtacacgag gcgaacaatt acgttttgaa gaacaagaag
    67621 cgacaaatca gctacaaaac atcataaatg aacttgaacg ttttgaaaaa gaaaagcaaa
    67681 tctcaacttt tgagacacgt gaactgcagc agtttatcga agattacgaa aagcaaacga
    67741 acgaattgaa agacaaacaa acagatcttg aatcgcaacg acaaaaaatc gacgaagaaa
    67801 tcaaatcgtt aagtcaagaa agcgaccaga tggaagccag aagagcacaa gtacaaagtc
    67861 aaaaagcaca agaacaagca gatcttgctg tcttgaaaga gcagtttaat catctgcaga
    67921 tccagctccg cggtgcccga gtccaaaaag cagaggcaac cgaacgtcaa gaagcgatag
    67981 aaaagcagtt ggcgacattg acagcagact tttctgatca tgaagtcaca gaagaaagtt
    68041 tggaaaaaca aattaacgaa ttatctgctc agcgagaaac attaaaagcc gagttggcaa
    68101 aagccaaaga gcagcgagat agaaggcaaa aggagatcga taagcttgaa gcagtcttgg
    68161 cagagcgtaa tcgtgagcaa aaagcacgac tgtcggaaca atccaaatta gaagtccaaa
    68221 aagaccgagc tgaaatgatt ttagataatc atttgaccta tctgcagtca gaatatcagc
    68281 tgacatttga gaaagcttcc caagactatc aagaaacaac cgatatcgaa gacagtagaa
    68341 caaaggtttc atccttaaaa gaacagattg aaaaactggg accagtaaac ttaaattcaa
    68401 tcgaacaata cgaacaagtc agtgaaagac atacattctt agcaacacag cgagatgatc
    68461 tgttagcagc gaaaaaccaa ttgtttgaaa cgatggatga gatggatgat gaagtgcgga
    68521 caagattcaa agaagtattt gaagctatcc gtcaagaatt caaaattgtc tttccaaata
    68581 tgtttggcgg cggtaaagct gaattagtac tgacggaacc aactgatttg ctgaaaacag
    68641 gtattgagat tgaagtacaa cctcctggca aaaaactgca aagtctaagt ttgctttctg
    68701 gaggagaacg agcacttaca gccatcgcgt tgctcttttc cattatccgt gtctgtcctg
    68761 ttccgttttg tatcttagat gaggtagaag cagcgttaga tgaagccaac gtgaaacgtt
    68821 ttggtcgtta cttgagcgat ttccaagatg acacacaatt tatcgtagtc acacaccgca
    68881 aaggaacgat ggtcgcagca gatgtactgt acggagtgac gatgcaggaa tccggtgtat
    68941 caaaaatcgt ttctgtacgg atggaagata tcaatgaaga ggcgaaaatc aacgaaacga
    69001 aagtgtagga acgaaaatga tcaaattagt agcaatcgat ttggacggta cattattaaa
    69061 tgaacaaaag ctgatttcag atgagaataa acaagcatta gcacaagcaa aacagcaagg
    69121 ggtcaagatc gttctatgta caggacgccc cttagctgcg atggcgcatt atctgcaaga
    69181 attaggactg gtagatgaag gtgactacag catcactttc aacggcggtt tggtacaaaa
    69241 aaatgatact ggtgaaatca tggaaaagaa agtgatggaa gtatcagata tccaacgctt
    69301 atacaaactg gctcagcaat tggatctgcc actagatgtt ttgtctgaca atgtggtttt
    69361 acagctgcct agtgccccaa ggaagcaatc cttgtacaat gtgttgaata agctgctgca
    69421 attccaacca gcggatataa gcgatattac agatgaattt gtgcttaata aggcagtaat
    69481 cgcttatgac caagaagaat tagatcctaa aatcaaagaa ataccagcag aattccatga
    69541 aatgtatgag atcatcaaaa caagaagtat gcttttggaa tttatgccaa aaggtgttac
    69601 aaaagcttat ggtatttctt tattggcaaa agatcttggt ttgaaacaag aagaaatcat
    69661 ggcgatcggt gatgaggaaa atgatttacc gatgatccaa tatgctggac taggcgtagc
    69721 gatggagaat gctgtgcctt tcgtcaaaga agcagcagat ttcgtgacag ccagcaatga
    69781 agaaaatggc gtagccaaag tgatccaaaa atttgtatta gagtaggggg agtcaaatgg
    69841 gattttttga taaaatcaag cgtgctttta ctggcgaaga gaaaacagaa gaagttgaag
    69901 tacaggagaa gtacgacaag ggtttagaaa agacgcgtaa aacatttggt gaacggatga
    69961 atgagttgtt tgccaatttt cgaacagtcg atgaagactt ttttgaagaa ttagaagaaa
    70021 cacttatcgg tgcagatgta ggttttgaaa cagcgatacg aattaccgaa gcattacgtc
    70081 aagaagtgaa actcagaaat gcgaaaaaat cggcagaagt ccaaaatgcg atcatcgaga
    70141 aacttgtgga tctctatgaa gcggaaggaa tcaatgaagt aaatgaacta aatatccaag
    70201 aagacggact aacagttatt ttgtttgtcg gtgttaatgg tgtagggaaa acaacaagta
    70261 ttggtaaact tgcccatcag ttcaaaaacg aaggtaaaaa agtattgatg gcagcagcag
    70321 ataccttccg cgctggagca atcgaccagt tagttgtctg gggcgaacgc gctggtgttg
    70381 aagttgttcg tggcaatgca ggaggcgatc cagcagctgt cgtattcgat gctttggaaa
    70441 gagcaaagac agagcaggca gatgttttac tagttgatac tgcaggccga ctgcaaaata
    70501 aagtgaactt gatgaacgaa ttagaaaaaa taaaacgagt aatccagcgg gaattaccag
    70561 aagcacccca agaaacactt cttgtattag atgcaaccac tggtcaaaac gcgatggttc
    70621 aagcaaaaca attcaaagaa acaacagatg tgaccggtct tgttttgaca aaattagatg
    70681 gtacagcaaa gggcggtatc gtacttgcta tccgtaatga attgcattta ccagtgaaat
    70741 tggtcggtct tggtgaagga atcgatgact tggagccgtt tgatccaaat gattttgtcg
    70801 ttggattgtt caaaggatta ctaaaagaag aataacccat gtctaaaaag caggagctgt
    70861 gacaaaagtt gcagctcctt gtttgaatga ttgtttttaa catagctgtg tttttgatgc
    70921 cttcattttt atacttattt gtaagcggtt ctcaaacaat ttcgttcttt ttcttagact
    70981 ttttgattat aattagattc atatgaattg gaggtcactt aatgatgaat tttaagcaat
    71041 tattattgca tgtcaatgcg cgccctttta tcgaccaagc tcgatttggt atagaacggg
    71101 aaggacagcg ggttgatctt gcaggaaatc tagcaaaaac cgatcatcca gcaatctttg
    71161 gcgatcgatc ctatcacccc tatatccaaa cagattttag cgaaacacaa acagagatga
    71221 tcacccctgt taccgattct attcccgaat tatttcagta tctcgctgct gtttatgatg
    71281 tgactgctcg ttctataccg aaagaagaga tgatctggcc attaagtatg ccacctgcct
    71341 taccggaaaa agacgaagag atcattattg caaaattaaa aaatttcgaa gatgtcttgt
    71401 atcgacgtta tttagcaaaa gaatacggga agcgaaaaca gatggtaagc ggtattcatt
    71461 tcaattttga atttggcgat gagttgctaa gaacattgtt cagccatcag gaagaatttc
    71521 aagatttttc cgaattcaaa acagaacttt atttgaaaac agcgagaaac tttatgcgct
    71581 atcgctggat gatcacttat ttattcggtg cttcaccaat gagtgagaag aactactttt
    71641 tagatgaatc acatccgcaa gaacctgttc gcagtattcg caacagtgcg ctgggctata
    71701 cgaatcatcc aaatgtgaaa gtttcctatg cttctatgaa acagtattta gcagatatcg
    71761 agcgaatgat cgaagaaggg aaactttcgg aggagaaaga attttataca ccgcttcgtt
    71821 tccgaggcgg aaagaaagtc gcagatttag caacaacagg tgttcgttat attgaattgc
    71881 ggaatatcga tttgaatcct tatgcaagat tgggtatcaa tccagagcaa gttcggttct
    71941 tacaattatt cctgatgtac atgttatgga cagaagaaaa agaagactgt gaccaatggg
    72001 tagcagaagg tacgactcga aataacaaag tagcactaga acaaccatca gatcaaacag
    72061 aatttcatca agaaggtaga gaaattcttg aaggaatgaa gcaaatgctg gttgaattgg
    72121 attggttgga ttctctttat ttagtagagg aagcattgac tcaaatggat catcctgaac
    72181 aaacgttagc agcgaaactc tatcaagaag cacagctatc gagtcagcaa gaagttgctg
    72241 tggcattggg acatcaatat tataaagaaa gccatgaacg tccctatcag ttggccggtt
    72301 ttcgcgaaat ggaactttct actcagatat ttatgttcga tgccatccaa aaaggtgtcc
    72361 aagtcaaagt attagatgag tcggatcaat ttttgcgtct gcaattccaa gaccatgtag
    72421 aatatgtgaa aaatgcaaac atgacaagta aggacagcta tatcgtccca cttatcatgg
    72481 aaaacaaaac agtaacgaaa aaagtcttaa aagaagctgg gttccgggta ccaggaggcg
    72541 cagaattttc atccatggaa gaagcggtaa aagcttatcc gagatttgcc gagcaggcat
    72601 ttgtgatcaa acctaaatca accaattacg ggttaggtat cacgattttc aaggaaggag
    72661 ctagtctgga agattatcaa gcaggtttag ccattgcttt tcgtgaagac agttcggttt
    72721 tagtagaaga atttatgccg ggaacggaat atcgtttctt tgtgatcgac ggagaagtcc
    72781 aagccatcat gttgcgagtc cctgctaatg ttattggtga cagtatccga acagtgaaag
    72841 aacttgttga agaaaaaaat agtgaccctt tgcgtggaac gaatcatcgt gcacctttag
    72901 aattgatcca attaggtgaa ttagaacaat tgatgttgaa agaacaaggg ttgacgatcg
    72961 aatcagttcc ccaagccaat caaattgttt atctaaggga gaactcaaat atcagtacag
    73021 gtggtgattc gatcgatatg actgatgaat tttctgaagc ttacaaaaaa atcgccgttt
    73081 ctgcggtaga agcactagga gctaagatta gtggtatcga tttgattata ccagataaag
    73141 aaatcgatcc tacaactgat aaaaaagcat atgggatcat cgaagcaaat ttcaatccag
    73201 ccatgcatat gcatgtttat ccttttgcag gaaaaggcag aagattgacg atgaatgtat
    73261 tgaaattgtt atatcctgaa gtattttaaa agaaaaagct tttgacagat tgtcctattt
    73321 gatgtcaatc tgatcaaaag ctttttttgc atgtaaaaat ttatgtgttt tttcgtttta
    73381 aaataaacga tcccagaagc tttttttctt ttttggtttt tctttttcag ctggcgaaga
    73441 gttttcttct gggtattttt tttcgatatc aatcacaggt tcatttactg cttcttttgc
    73501 tgttaagagc aatccgaatt cctcaggatt tgcagtgacg taatcgttga ctacagtgaa
    73561 acggctattg tttttcgttg ctagctggat atattggttt tggacagaaa ggggtagagc
    73621 cccattcaag agtatggaag catctggatg ttttttgagt tcttttaaaa agttttcttt
    73681 gttttttggt tggatcattt cagcaacagt catactaaga tagcagcgtt ccctgaatgt
    73741 ccctaaatat ttatgctgtt cttcagggtt cactaaaggt gtaccataaa gtcccttatc
    73801 caaatggctt tttacatcat cttgtgccat aaaaaatacc ctccttcttc tctttgtctt
    73861 tcttacgatt atagcatatt cccaataata cctaaaacat atgaaaaagc ggttgctttt
    73921 gttcaacgat tcacttaaaa taagaatgaa aatcattctc aattagaaag gtggattgga
    73981 tgcgctacgg acgactagta gcattattag ttattttaag tagtatttca ttgttcatcg
    74041 gagtatcgaa tgtacaattg tcagaactgc tccagttaga tgggcaaagc ttacaaatct
    74101 tgctagtgac tcgtttgcca cgaacgattt gtttgatcct tgtgggagcg accagtagta
    74161 tttgtgggtt gatcatgcaa catttgaccc aaaataaatt tgtttcacca acgactgcgg
    74221 gcacgatgga tagtgcgcgt ttaggtattt tagtggctat gattttccta cctggtgcat
    74281 ccttgattgt ccgatccttg acagcatttt gctttgcttt tgcaggaaca ttgctttttt
    74341 tatcccttac gcgattgttc ctccagaaaa atcaattgat gcttccgttg attggagtca
    74401 tgttagggaa tatcattggt tcagttgcta ctttttttgc ttatcaattc cagttggtac
    74461 aaaatatgac ttcatggctt caagggaatt ttgcgactgt gatacgagga aattatgagt
    74521 tattgtatgc tgttgttcca ttgttgctct tggtttggct atttgcttac cgatttacga
    74581 tcattggtct gggcgaatcg tttgcagtaa atctgggaat agattaccag aagatgcagt
    74641 ttttaggcat tggcttagta tcattggcta gtgcagtcat gttgatcatg gtaggaagca
    74701 ttccttttat cggagtgatc attccgaatc ttgtctctag aatatatgga gatcaagtgc
    74761 acaaaacaat tggcgtaact gctttagcag gtagtttgtt cttagtattt tgcgatcttg
    74821 tcgctcgcgt gttgattttt ccttatgaaa taccagtcag tgtgatcgtt ggaatcatcg
    74881 gtggggctat cttcctttat cttctgataa ggggacgacg atatgcttaa aaaaaagcca
    74941 tctattttta ttggtatgct tgttcttgtt ttatttgtta caggaatgta cttgacgatc
    75001 catacatatg gaaactggca ttttgcatgt gcattgagga gtaagaaaat ttttgcattt
    75061 atccttgtct cgctagctgt cagcagtgcc acaatcagct ttcagacaat tacgcataac
    75121 cagtttttga ctccttcagt attgggactt gagtcgttat atgtccttgt ccaaacggtc
    75181 cttttcttct ttatcggagg agtgacgatg cttcagcaga caggtacagt ttttttctta
    75241 ttgaacgttg ggctgatggt cgggctgagt ctattgttat ttttctttct tttgaaaaaa
    75301 atgagagcga atcttttttt attactgatg tcagggatga ttttaggtac gctttttggt
    75361 agtgtcagta cctttttaca agtcatcatg gatccgaatg aatatgattt gcttcaaggc
    75421 agattatttg caagctttgg caatatccag agtcagtatc ttttgcctgc ttctttgatc
    75481 attatcggct gctggtacct gttatttcga tatcgacatg tgctagacgt tttccatctc
    75541 ggaaatgaac aagcagtaaa cctcgggata gacacagatc gttttgaatt tttgatttta
    75601 tgttgtgtca gtcttttgac agggacatca acggctcttg tgggtccagt tactttttta
    75661 gggtttattg tcgcaaatat cagttatcgt gtcttttcta cttatcgtca tggtcagcta
    75721 tttatcggaa gctttctggt agctatgctg tttctgacag gaggacagct cgcagtagag
    75781 cagattttcg gctggaatac aacagtgagt gtcgtcgttg aatttgtcgg aggaatttat
    75841 tttgtcacaa aattgattcg cgaaaggaag agtatcctat gattgattta caaaaggtca
    75901 ataaactgta ccatggaaaa tcagtggtta aagatgtaca gttaacgatt cctgaaaaga
    75961 aattgactgc ttttatcggt ccaaatggtg ctggaaagtc aacggtgttg tcgatgatca
    76021 gtcgtttgat accaaaagat acaggtgaaa tctatttaga ccataacgaa gtaaaggctt
    76081 ggaaatccaa tgaattagcc aaaaaattat cgatcctacg acaatcgaat gaaataaatg
    76141 tccaaatcac cgtgaaagaa ttagtagaat ttggacgatt tccttatacg aaaggaaaat
    76201 tgacgacaaa agacgaggaa atcgttcagg aatcactgga acaccttggg ttagaagaaa
    76261 tagcggatca atcgattgac actctttcag gcggtcaact ccaacgtgcg tatattgcaa
    76321 tggtgctagc gcaagacacg gattatattt tactggatga acctttgaac aatctagata
    76381 tgaattttgc ggttcaaatc atgcagattt taaaaaattt agtacaagaa atcgggaaaa
    76441 caattgttat tgttcttcat gatatcaact ttgctgcaag ttatgcagac gaaattgttg
    76501 caatgaaaga tggacagtta tttacgcaag gaacgaccca agaaatgata aaaaaagatg
    76561 tattggatga attatacgaa atggacatac ggatttgtga gattgaaggc cgcagattct
    76621 gtctttattt ctaaaactaa cattaggaga gaagagatga aaaaattagt agtaggtatc
    76681 ttgattctag catcatttgg tttagcagca tgtggaaata gcaacaacac cagtcaggca
    76741 gacacaaaaa aaagcagcac acaaactgaa actacattga cgataacaga tagtaatgga
    76801 gaccaaatcg aggtgccaaa taatccagaa aaagtcgtcg tattcgacaa tggttcttta
    76861 gatacgatgg atgctcttgg tgttggagat aaggtagttg gagcagctac aagcagcctt
    76921 cctgagtatc tttcatccta taaaaaagta gaatcagcag gtggaataaa agaaccagac
    76981 ttagaaaaaa ttaatcagct tcagccagat ctaatcatca tttctggccg acaaagagat
    77041 tttcaaaaag atctaagtca aattgctccg accattttcc tttctttaga tgcgaaaaat
    77101 ccatgggaat ctttccagca aaatgtcact gctttagggg agatctttgg taagcaagaa
    77161 gaagctaaaa ctcaattaga ggaattatct agtgcaatcg atcagacgaa aaagaaagca
    77221 gaagctactg acaaaaaagc actagtcaca cttgtgaatg aagggcaatt atcagcctac
    77281 ggatctggtt ctagattcgg tttcatccat gatttatttg gctttgaaca agcagatgat
    77341 caaatcgaag catccactca cggtcaaagt gtttcttatg aatatgtgct ggaaaaaaat
    77401 ccggatatct tatttgtagt agacagaaca aaagctattg gtggagacga cagcaaagat
    77461 gatatttctg ccaatgaact ggtagcacaa acgaatgctg gtaaaaatca gcagatcatc
    77521 tcccttgaac cagatgtctg gtatttaagc gggggcggtt tagaatcaat gaaactgatg
    77581 atcgaagatg tgaatcaagc atttaaatag cataaataac agaggattaa actctcatac
    77641 tatgtaacaa taatgtttct tacattctta aatagcaaga gcctatcctc aaagaagtta
    77701 tcaaaaacca tccgtaaaat cgtattgatg attttacgga tggtttttat ttatttgaga
    77761 aatctttttt caacgtgaat tcattatcta catcatacgg gttgattcta gaatggggag
    77821 tggcaaaaaa tagtgtgatc cattttttca gcatcaagat cgcctccttt gatttgaatc
    77881 aaaggtacaa agcgaaactt agataaaact taaatttaga tatttttatt ttgtaccgat
    77941 ctcttcttta aacgatgttc catctgctgc ttctcggcaa taagtccact agactagaaa
    78001 atatgagaag ctattttctg tccagcgttc ttattactca aagcaaatcg cagttgtcac
    78061 aatctcttct aaacgatgtt ccatctgctg cttctcggca ataagcccac tagactagaa
    78121 aatatgagaa gctattttct gtccagcgtt cttattactc aaagcaaatc gcagttgtca
    78181 caatctcttc taaacaatgt tcaatcagct gaccttcggt attagctcaa agcactgatt
    78241 tcacaacctc tatttaggca tgtgtctcag caagcggttg atagttgatg atctgcattt
    78301 ttcgataaaa atcggcggga agcttactcc accgttttaa taattgatag aaataactct
    78361 cttctgcttt gattttatac tcgcttaata tcaatccaaa actattcgtt ttttttgaag
    78421 ctaatttttt ataaatatcc aatgctttgg ttttatcttc attgacaaag agtgttttta
    78481 cttcaatata agaaccctcg atattttgtg tttcttcgat aaaatagatg ttttttatat
    78541 attccttcat agtgattcct ccaaagaagt cttttatttg ataagtttac tctaccgaag
    78601 agttgttaat aatccgtgaa caaaaagtaa ttctttttcc aatagttgtt aaaggttttt
    78661 tattttttat agtatttttt gttatttaag aaaggaataa ggttaaacaa ataacaggtt
    78721 gctttttggg tctttttccg ttcaagaaac tgaacgaaga aaagggaaag ttgtctcttt
    78781 tgtgataaga gaaatcataa taaacgaatg acttactttc caataaattg agaacagtca
    78841 gaaccagaca aattagttgc atctgatgaa taaagtgatt attctatgac atgaggtgat
    78901 acagatgaaa ttagaagtga caaaagaagc acaagaagta ttgaagaata aattagaagc
    78961 agacgatcaa cttttattag atatcgaaaa cggtgacggt ccatttgcag aaagccaagt
    79021 cagttgccaa ttggatacgg catttcgatt gatcattgtc aaaaaagata cacaaacaga
    79081 tctaagtctt tattctgtag tggctgatac accagttgga ccaatcaaaa tcaaagacag
    79141 tgcaatactt tacatggatg atccatccac acttgcttta gaaccaactt ataatagttt
    79201 acaattaaaa ggaccaagcg gcttgagaaa aggcaacttg caagttgttc gaaaagacta
    79261 gagggataaa atgggaaaat tggcgatcat cagcgaccta catgtggaca tcaataaatt
    79321 cggcgaatca gagctgatgc agctttggca agttttgcaa aagcacaaga tcactcggct
    79381 tcatctagcc ggagatacgg ctaataaagt agaccgttgc ctagctgttg tcgaattttt
    79441 cgtcaataaa ggattatcta cgacatttca tttcggcaat cacgagttgg cagatgtgcc
    79501 caatgaacag atgatggacc attttccaga cccacatttt ttaaatgaac ggtatattgc
    79561 tttaaatgag cagaccgttc ttttagggat gaatggctgg tacgactatc agttttccga
    79621 attgaaagat tacgaggcaa tcgtacgaat gaagcgtttg tattggtatg atcggttcat
    79681 ccagcgtggg aaaacagatc tcgaggtcaa tgcagaaatg cttgcagctg caaaaaattt
    79741 gctagaccag ctggaagcaa aaaaacttga ggtgatttta tccactcatt tcgttcctaa
    79801 acgggcattt atcatgtatc aatctgctcc ttatgagcgt tggaacaaat taaatgcatt
    79861 tttaggatca gaatcattcg gagaattact tgaccgttat tcaaatatca aacaagtagt
    79921 ttttggccat acgcatcgtc gctttgaaga taaatccatc ggtcacacga tttacagctg
    79981 cagacctttt ggttattatt atgaatggca gctgacccga gattttgtct tgaaagaaca
    80041 gttgctagac agctatgatc ctatgaaatt acgtgtcctc ttgcgtgccc atcacccagc
    80101 ttttcaggcc tatcaaacac aacatttgca agaggaattt gaacaagcga tgacaatcgt
    80161 tccgtattga gacagcatta gtaatgtgta aaagaaaata ccttgtaaaa cataaggata
    80221 agtaagagca gtagatccat ttatcgtgga tatgctgctt tttttgcgga aaataatcag
    80281 cgaatgttta tttgatcgga tgatttgtaa ctcgcagagt actagatgca agcgtgtatt
    80341 ctttttttga acgataatca caaaaaaaaa tataatatac attttttatt taattataat
    80401 taatattgat tgaagtctag gcagtcaagt cacattttga tagataggag ggggacttac
    80461 gaattatttt aaaggctatg acagctgtat ttctagattg tgtttgcatc aagttgcaat
    80521 aaaaactaga aatcaaatcg ggctgataat catttataac taatcgatac ataggaccaa
    80581 atataggtct atgttctttt atttcataag tatcgtaaaa cagaattttg ctatggatta
    80641 atccaatcga ctgatatgtt tagtaaataa agaaagagga atgtcaatga tgaaaaaaga
    80701 aatcgtatta acagcagcaa tgatgttatt cagcatggta gcaagtacga cttttgtttc
    80761 tgcaactgaa gtatacccaa aggaatataa cacagaagga acgattacat ttgaagcagg
    80821 agatgagggt gtaactcctc ctgttgatcc agagaatcct gatcccaata aacctgtcga
    80881 tccatcagat cctccaagcc ctggaacagg aggggcatta tcgattgatt atggatcaaa
    80941 attcaaattt gggactcaaa aaatttctac tgcggataaa acgtattatg cagctgctga
    81001 tgtgatgaac gatgggtcta gaaaaccgac atatgtccaa gtgacagata ggagaagtac
    81061 cttatctggg tggaaattaa gtgtctctca accagaacag tttaaaactg ccagtgggga
    81121 tgaactagtt ggagcacagc tgaaatttac gaaagggcag gctgtttctt tggttgatcc
    81181 aacatatacg ccgcaaacgg tgaattctga attaacgttg acaccgggag gaaacaatac
    81241 gttagcaatt aatgctaaat caggaacagg tgtggggact tgggtctatc gatttggtgc
    81301 aaatgaaaat gaaaatcaag atgcggtaca gctttcggta cccggtaaat ctgtcaagtt
    81361 agcgcaacaa tattccacta aattagtttg gacattagaa gatacaccta acaactagtt
    81421 tactgaaaag aactgttaaa aataaatacg tagtcatatt gtcttgcgag gtaatcgagc
    81481 aaaaattgtc aaaggctagg ctaaatttgt ttggatacga atagttcatc taggaattta
    81541 acgatcagga ggaaaagata tattgaaaaa gaggaggatc gtgctcattt taagcagtct
    81601 cttagtgact aatatctttc cgatcatagg gtactctttg gaattgaatc agttggagca
    81661 tggaaataga agagacgaag aaagcaaact cacttcgaca ttcgacagtt taatagaatc
    81721 caaccagaca caagaaagca gtgaggattt aagtatttcg agtagtggag agaccactga
    81781 caacgtagaa gctgagggtt cggacaaaca aggactagaa gatgcaccaa tttctgcggt
    81841 tgagctgcct gacgatccca atattatttc tatcgataaa atttttcaaa cacctatcgg
    81901 tactagcacg tccatattgg aaaatgggaa gttactgcag ttgaacccag cagaaaggtc
    81961 tcaaagagga gctatttggt caaataagaa gattagttta ctctcggatt ttacatttaa
    82021 atcttattta tacttaggaa atcaacgaga tagagcggga gatggcatga cctttacatt
    82081 gactggcgat cctagaatgg ctagtaatcc cagtcaagtt attggatcgc caggtatggg
    82141 aattggctca tattctactc gttctggcca accttacatt gcgaatgcgc tctcgattga
    82201 gtttgatacg tataaaaata gtggttcttc tgatcgaatg gatcgagaga taactgctga
    82261 taatagaggg catggacatg tcgcttttgt cacgcctaaa ccaaataata ataattattc
    82321 tggagagcat actggcgtga cggtagctcc tacatttctt tctaatggca catggcgctt
    82381 gttaataatt aaatgggacg cggagcaaag aagtcttact tatgatttgg aaggtgtcgg
    82441 tcactcttct cggattatac ctgatctcat taggcagttt ggttctacag aagtaaattg
    82501 ggggtttact tcttcaacag gtactttttt tcaagaaaat gctgtcgctg tcacgcgact
    82561 tccatcgaat gtcacatcaa cagctgatgt aaaagtcaac gatagtgatt atggggccat
    82621 cgctgaagct ggaggaaacg ataagataac tatcagaaat acattgaagg tcgaggggga
    82681 ttttcttgaa tataagaaaa tgcagactag tatcgacctc ccacaagaat taactattcc
    82741 cgagcatatc ttgatcaatg gaaatcaaat tgatgccaaa gatatcttga taaccggaaa
    82801 tcgagtcacg ctaaatctga cagattattt tattgctgga gatacgttaa taatcgaatt
    82861 ggagacaact ttgcaggaag taattcctga aaaagtactc actatgcatt ttgaatacct
    82921 tgaaaacggg aatttgattg agcaatcgaa tgaaataaac ctaaagatcg caaagctgaa
    82981 ggagatagat atccatgttt attataaaga taaagacagt cagattgata ttgctgaaat
    83041 gaaaacaatc actgggaaaa taggagagaa gtataaagaa actcctattg atattgaagg
    83101 gtatgttttt gactcggatt cagcgaatac agaaggcatc ttctccgaaa atacagagga
    83161 tatctatttt tattacagaa aaggcaaact ttatctctca actgctcctc aatatgtcaa
    83221 ttttggaaaa cataaaatat ccagtagacc attaagtgaa ttcggacagt tttcaggtgg
    83281 gttgaaaatt atagatgaac gggcttttgg aagttggaaa ttacaattga aacaagagaa
    83341 agttcttaca aatggagatt ttgagcttcc agaagctctt tcctttgtta cctctgaaaa
    83401 tacaacggtt atagggacat ccgctgttac gattttcgaa agtgatcaaa agggtgaaag
    83461 cgatttgtcc tctcttttag attctacagc tcatcgtgga atcagaatag atattcctgt
    83521 agaaaaccaa agaatcggaa cctttgaggg gaaactatct tggatacttg cagatgtccc
    83581 aggaaattaa caggaagaga agaatataac aaaattattg agtttcaaga agggcacagg
    83641 taccataggc tcttgtgtcc cacagagaca agattttgtt atagtcttct cttacatatg
    83701 attaaaggag cgattttctt gagaccaaaa caacaattat ttataacact cctagttatt
    83761 ttaggggcac tttttaacaa tatatcagtg tcagctagtg catttaattt ttcagtgacg
    83821 ccgataactt cagagaatca aatcgacaag agaaaaactt acttcgatct tcaacttgat
    83881 ccggatcagg aagtagaagt aaaagcggaa ttgagaaatg atacagaaaa agaagtgaaa
    83941 atcgatattt ctgtgaatag cgcaaccacc aattcaaatg tgatggttga atacggaaaa
    84001 aacgagattg aaaaagacat gagcctgatc tttgatctgg tagattatgt gagctatcca
    84061 cagatagtga cgctaaaacc taaaagtgtc caaaccgttg cttttcatgt caggatgccg
    84121 aatgagcgat ttgatggtgt attggctggt gggatcacat tccaagaaat ccagacggaa
    84181 aaggaccaaa cagaaactaa ggatcaaagc ttatcgattg agaatgaata cacctatatt
    84241 attgctttgt tgatgcaaca gacactgaac gaagttgctc cgaaccttac tcttcatgaa
    84301 gttaaaccag atcaaatcaa tgcaagaaat gtcatcttag caaacgttca aaatgatcaa
    84361 aaaacctata tcaatcaagt agttattgaa acaaaaatta caaaaaaagg acattctgaa
    84421 gttttatatc aagaggaaaa agaaggattg cagattgcgc cgaatacaaa tttttctttt
    84481 ccaactgctt taaatggtca accgctaacc ccaggtgaat atcaccttac aatgactgtt
    84541 ttaggaaatg aaaatgaaaa tggaaaattt tcgagaaaaa aaggaaatac tacgatcaac
    84601 tataccaatc aatgggtatt tgaaaaagat tttacaatag acggaaaagt agccaaggaa
    84661 ttgaacacga cggatgttac gattaaaaaa gacaataatt ggatttatat cttagtagct
    84721 tcacttttct tattgtttat tttattatgc atacttttgt ttgttttgag aaaaaaagaa
    84781 gagaaagaaa agtaaggtta agataacaaa tagtaaattt ttattattgt aggatggttg
    84841 ggctcttttt ataacaatat aaaatatacc attttattaa taaaaatgca tactagtaaa
    84901 tgatataatt ctaataacag gtttgatcgc gagaaaggcc aaataaaacg ctctccaaaa
    84961 tgttaaaaaa aagacaggac gatgtatatt atacaaacaa gaatcgctga caacagtgac
    85021 tcggatccag gaaatcagtt ttatccccag ctagttggtg aatgcatgga aagtaatata
    85081 cgtagaaaga gctgatgact aatgaattat gagttttttt taagcaaaga agatcacaga
    85141 agttattcat tacttaaata tttagaagca agctcaaatt tatcagagtc aatatcgaat
    85201 gttcaagaag agttgtcgct atcgacattt ctcttgaaaa aaacgatcga taagctgaaa
    85261 catgatttac aaaagttcga tctagagaaa aatttgcgag taaccgtcag tgaattggat
    85321 atatgtctgg aaattaatgg aaaatgttct agcaaagctc tgttatctcg ttatataacg
    85381 gattctttat ctatgaaaat ggtattggct ttctttcagg aaaaatatat ctcagtagaa
    85441 aattttgcta aacagcatca cgtgagttat tctgtggctt ataaagtatt acaaagacta
    85501 aaaagaaatc taaaaaaata tcaaattttt tttgaaaaga gaaagttga
//
LOCUS       DAPBBR010000003        83731 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPBBR010000003 DAPBBR010000000
VERSION     DAPBBR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 83731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.003"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..142)
                     /locus_tag="RD488_000181"
     CDS             complement(<1..142)
                     /locus_tag="RD488_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAT RNA binding domain-containing protein"
                     /protein_id="HDT7656287.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKE"
     gene            complement(452..1165)
                     /locus_tag="RD488_000182"
     CDS             complement(452..1165)
                     /locus_tag="RD488_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7656288.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(1233..1559)
                     /locus_tag="RD488_000183"
     CDS             complement(1233..1559)
                     /locus_tag="RD488_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7656289.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(1682..1909)
                     /locus_tag="RD488_000184"
     CDS             complement(1682..1909)
                     /locus_tag="RD488_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7656290.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(2231..3484)
                     /locus_tag="RD488_000185"
     CDS             complement(2231..3484)
                     /locus_tag="RD488_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7656291.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            3545..4284
                     /locus_tag="RD488_000186"
                     /pseudo
     CDS             3545..4284
                     /locus_tag="RD488_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(4370..5128)
                     /locus_tag="RD488_000187"
     CDS             complement(4370..5128)
                     /locus_tag="RD488_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7656292.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(5125..6153)
                     /locus_tag="RD488_000188"
                     /pseudo
     CDS             complement(5125..6153)
                     /locus_tag="RD488_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(6173..9340)
                     /locus_tag="RD488_000189"
     CDS             complement(6173..9340)
                     /locus_tag="RD488_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656293.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(9564..10448)
                     /locus_tag="RD488_000190"
     CDS             complement(9564..10448)
                     /locus_tag="RD488_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7656294.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(10543..10980)
                     /locus_tag="RD488_000191"
     CDS             complement(10543..10980)
                     /locus_tag="RD488_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656295.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(11197..12108)
                     /locus_tag="RD488_000192"
     CDS             complement(11197..12108)
                     /locus_tag="RD488_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7656296.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(12565..12993)
                     /locus_tag="RD488_000193"
     CDS             complement(12565..12993)
                     /locus_tag="RD488_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656297.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     EKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(13021..13659)
                     /locus_tag="RD488_000194"
     CDS             complement(13021..13659)
                     /locus_tag="RD488_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656298.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(13663..15645)
                     /locus_tag="RD488_000195"
     CDS             complement(13663..15645)
                     /locus_tag="RD488_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDT7656299.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            15825..16490
                     /locus_tag="RD488_000196"
     CDS             15825..16490
                     /locus_tag="RD488_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656300.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(18425..21574)
                     /locus_tag="RD488_000197"
     CDS             complement(18425..21574)
                     /locus_tag="RD488_000197"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HDT7656301.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(21587..22786)
                     /locus_tag="RD488_000198"
     CDS             complement(21587..22786)
                     /locus_tag="RD488_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDT7656302.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLIDLVVRLNKSTNSSRLPKVEF
                     EDIVAGEGRLNKDVSQKFDNRKGIEFLPNDILYGKLRPYLKNWLKATFTGVAIGDFWV
                     FRAKKSDSDFIYSLIQADRYQKAANDTSGTKMPRSDWKKVSDTVFYIPNDLKEQQKIG
                     IFFKKLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWEERKLGE
                     LGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIERKKWKPI
                     KDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFETINLPR
                     YSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLLKETKKS
                     FLQKMFV"
     gene            complement(22776..24371)
                     /locus_tag="RD488_000199"
     CDS             complement(22776..24371)
                     /locus_tag="RD488_000199"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDT7656303.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEMWLQGALEVFKHEQ"
     gene            complement(24883..25665)
                     /locus_tag="RD488_000200"
     CDS             complement(24883..25665)
                     /locus_tag="RD488_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656304.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(25730..26566)
                     /locus_tag="RD488_000201"
     CDS             complement(25730..26566)
                     /locus_tag="RD488_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7656305.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(26584..27993)
                     /locus_tag="RD488_000202"
     CDS             complement(26584..27993)
                     /locus_tag="RD488_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7656306.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(28007..29830)
                     /locus_tag="RD488_000203"
     CDS             complement(28007..29830)
                     /locus_tag="RD488_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7656307.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(30673..30999)
                     /locus_tag="RD488_000204"
     CDS             complement(30673..30999)
                     /locus_tag="RD488_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656308.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(31045..31407)
                     /locus_tag="RD488_000205"
     CDS             complement(31045..31407)
                     /locus_tag="RD488_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDT7656309.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(31444..31659)
                     /locus_tag="RD488_000206"
     CDS             complement(31444..31659)
                     /locus_tag="RD488_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7656310.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            31786..32121
                     /locus_tag="RD488_000207"
     CDS             31786..32121
                     /locus_tag="RD488_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7656311.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(32197..34194)
                     /locus_tag="RD488_000208"
     CDS             complement(32197..34194)
                     /locus_tag="RD488_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656312.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(34292..34567)
                     /locus_tag="RD488_000209"
     CDS             complement(34292..34567)
                     /locus_tag="RD488_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656313.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYH
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            34799..35533
                     /locus_tag="RD488_000210"
     CDS             34799..35533
                     /locus_tag="RD488_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7656314.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            35572..36714
                     /locus_tag="RD488_000211"
     CDS             35572..36714
                     /locus_tag="RD488_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7656315.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(36809..38200)
                     /gene="sufB"
                     /locus_tag="RD488_000212"
     CDS             complement(36809..38200)
                     /gene="sufB"
                     /locus_tag="RD488_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDT7656316.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(38205..38675)
                     /locus_tag="RD488_000213"
     CDS             complement(38205..38675)
                     /locus_tag="RD488_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDT7656317.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(38662..39897)
                     /locus_tag="RD488_000214"
     CDS             complement(38662..39897)
                     /locus_tag="RD488_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7656318.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHRAIDVQALDCDF
                     FAFSGHKMCGPTGIGALYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(39894..41180)
                     /gene="sufD"
                     /locus_tag="RD488_000215"
     CDS             complement(39894..41180)
                     /gene="sufD"
                     /locus_tag="RD488_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDT7656319.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSTVDQLGKNITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(41193..41966)
                     /gene="sufC"
                     /locus_tag="RD488_000216"
     CDS             complement(41193..41966)
                     /gene="sufC"
                     /locus_tag="RD488_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDT7656320.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFNGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(42163..43011)
                     /locus_tag="RD488_000217"
     CDS             complement(42163..43011)
                     /locus_tag="RD488_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7656321.1"
                     /translation="MKKKIFGLAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDNIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(43035..43721)
                     /locus_tag="RD488_000218"
     CDS             complement(43035..43721)
                     /locus_tag="RD488_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656322.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(43714..44748)
                     /locus_tag="RD488_000219"
     CDS             complement(43714..44748)
                     /locus_tag="RD488_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656323.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(44811..45067)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(45143..45481)
                     /locus_tag="RD488_000220"
     CDS             complement(45143..45481)
                     /locus_tag="RD488_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDT7656324.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(45483..45839)
                     /locus_tag="RD488_000221"
     CDS             complement(45483..45839)
                     /locus_tag="RD488_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDT7656325.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(45845..47032)
                     /locus_tag="RD488_000222"
     CDS             complement(45845..47032)
                     /locus_tag="RD488_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7656326.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYFYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVVGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(47223..48068)
                     /locus_tag="RD488_000223"
     CDS             complement(47223..48068)
                     /locus_tag="RD488_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7656327.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YPLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            48302..49267
                     /locus_tag="RD488_000224"
     CDS             48302..49267
                     /locus_tag="RD488_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDT7656328.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYQSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            49767..50810
                     /locus_tag="RD488_000225"
     CDS             49767..50810
                     /locus_tag="RD488_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDT7656329.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(50872..51336)
                     /locus_tag="RD488_000226"
     CDS             complement(50872..51336)
                     /locus_tag="RD488_000226"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDT7656330.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            51581..52528
                     /locus_tag="RD488_000227"
     CDS             51581..52528
                     /locus_tag="RD488_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7656331.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDVDSVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(52739..54811)
                     /locus_tag="RD488_000228"
     CDS             complement(52739..54811)
                     /locus_tag="RD488_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7656332.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKEMRINPDF
                     TIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(54744..55121)
                     /locus_tag="RD488_000229"
     CDS             complement(54744..55121)
                     /locus_tag="RD488_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDT7656333.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(55250..55828)
                     /locus_tag="RD488_000230"
     CDS             complement(55250..55828)
                     /locus_tag="RD488_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7656334.1"
                     /translation="MRGNMKMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLEGIHETNQIILQIFEAFQLTKEEKVHRSRELCSMIHGYL
                     SLRFLGYFTKESTIDPEDSYFWMINDFIATLP"
     gene            55960..57252
                     /locus_tag="RD488_000231"
     CDS             55960..57252
                     /locus_tag="RD488_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7656335.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLAHQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNAAALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLMGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            complement(57312..58430)
                     /locus_tag="RD488_000232"
     CDS             complement(57312..58430)
                     /locus_tag="RD488_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HDT7656336.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(58444..59865)
                     /gene="arcD"
                     /locus_tag="RD488_000233"
     CDS             complement(58444..59865)
                     /gene="arcD"
                     /locus_tag="RD488_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDT7656337.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFAIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVAFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(60111..61232)
                     /gene="mnmA"
                     /locus_tag="RD488_000234"
     CDS             complement(60111..61232)
                     /gene="mnmA"
                     /locus_tag="RD488_000234"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDT7656338.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNHAEVVFD
                     EPVRAITPGQAVVFYDEMECLGGGLIDHAYQETKVLQYV"
     gene            61636..62235
                     /locus_tag="RD488_000235"
     CDS             61636..62235
                     /locus_tag="RD488_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7656339.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(62385..63658)
                     /gene="efmA"
                     /locus_tag="RD488_000236"
                     /pseudo
     CDS             complement(62385..63658)
                     /gene="efmA"
                     /locus_tag="RD488_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
     gene            complement(63929..64273)
                     /locus_tag="RD488_000237"
     CDS             complement(63929..64273)
                     /locus_tag="RD488_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HDT7656340.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(64410..65555)
                     /locus_tag="RD488_000238"
     CDS             complement(64410..65555)
                     /locus_tag="RD488_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7656341.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSCQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLEQLVRAVKK"
     gene            complement(65735..66709)
                     /locus_tag="RD488_000239"
     CDS             complement(65735..66709)
                     /locus_tag="RD488_000239"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7656342.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(66789..67664)
                     /locus_tag="RD488_000240"
     CDS             complement(66789..67664)
                     /locus_tag="RD488_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HDT7656343.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     ALIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKEWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            67794..69701
                     /locus_tag="RD488_000241"
     CDS             67794..69701
                     /locus_tag="RD488_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HDT7656344.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(70241..73555)
                     /locus_tag="RD488_000242"
     CDS             complement(70241..73555)
                     /locus_tag="RD488_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HDT7656345.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESCTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIKLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSFLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNESPNESPNESPNESPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGG
                     ILLIGVVVYVMKQRKK"
     gene            complement(73827..74372)
                     /locus_tag="RD488_000243"
     CDS             complement(73827..74372)
                     /locus_tag="RD488_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7656346.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(74384..75076)
                     /locus_tag="RD488_000244"
     CDS             complement(74384..75076)
                     /locus_tag="RD488_000244"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDT7656347.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(75095..75379)
                     /locus_tag="RD488_000245"
     CDS             complement(75095..75379)
                     /locus_tag="RD488_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656348.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(75392..75955)
                     /locus_tag="RD488_000246"
     CDS             complement(75392..75955)
                     /locus_tag="RD488_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7656349.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            76182..76832
                     /locus_tag="RD488_000247"
     CDS             76182..76832
                     /locus_tag="RD488_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDT7656350.1"
                     /translation="MIKRNWPWLLALVLLFLFGFSFVLGLLLIGVVLVLWGLFGSRRK
                     KGKQEEIPALTNELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAKLKAI
                     DLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIKNKQT
                     YEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQKD"
     gene            76956..78152
                     /locus_tag="RD488_000248"
     CDS             76956..78152
                     /locus_tag="RD488_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDT7656351.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(78253..79629)
                     /locus_tag="RD488_000249"
     CDS             complement(78253..79629)
                     /locus_tag="RD488_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7656352.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSFSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIISILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(79666..80532)
                     /locus_tag="RD488_000250"
     CDS             complement(79666..80532)
                     /locus_tag="RD488_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HDT7656353.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(80621..81646)
                     /locus_tag="RD488_000251"
     CDS             complement(80621..81646)
                     /locus_tag="RD488_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7656354.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYRLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(81664..82338)
                     /locus_tag="RD488_000252"
     CDS             complement(81664..82338)
                     /locus_tag="RD488_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7656355.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKP
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(82519..83415)
                     /locus_tag="RD488_000253"
     CDS             complement(82519..83415)
                     /locus_tag="RD488_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7656356.1"
                     /translation="MKKRTGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     RNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYWKFKRQKQLRKNNRS"
     gene            complement(83489..83614)
                     /locus_tag="RD488_000254"
     CDS             complement(83489..83614)
                     /locus_tag="RD488_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7656357.1"
                     /translation="MKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKFKMKSEV"
BASE COUNT        24358 a        17416 c        14371 g        27586 t
ORIGIN      
        1 attctttttg gaccgcttct ggcgaaatct cgtccccaat ctttttttga aaagctagtc
       61 cttttcccat acaaacgact tcttccccga atccattttt cgaaatgacg acattgttat
      121 tcaaaatttt atcaattttc attttgcttc gccctctcaa gaaaaataaa aaaacctaga
      181 attcgcctac tgtttcttag ctgaattctg gttttgcctg ccgtacagta acaatccatt
      241 tcttattcaa aatcatcata ccatcgaatt tttatttatg caagcctttt catataaaaa
      301 ataaaagaac tggaacacaa gtctatctag aaaacaacca aatcagagat gcacctcttt
      361 gcgtttctct ttttttcagc aaattggttt ttccttatcg attcatatcc tttggctgtt
      421 tttaatctgt aacgacttat gtcccagtat cctaaaatgt ttttgtctct agattgaaag
      481 cagatctcat atcatctgtc gcatctttta tcgatgtaac actttccagt tctccttgta
      541 caactagtcg cgtgacggcg tccatgtcgc cacaagtaat tagtgtgaca atttcttttc
      601 cctcgacttc attcagtaat tgggtatctg taggagcaac tttttcttta aaaaatgttt
      661 tgtatgtata cacattttct aaatctgtca aatagatctt ggcacccatc tctaaatttt
      721 ctagcggtgt aaacagcaat tcagggttcg ttgcacgatg gcttgctaag gcataatttc
      781 cttttcccat ttcttgatct ggagataatg ttcctgctcc gtaaagtagt gacgtattat
      841 ccaagccttt gaaaaccggt aaattgattg aaactgaagg gactgcgata ctagcaatca
      901 ctggtagatc tgttcctctc atttgcgacc tcatgacccc ttctgtcgtc attggttcta
      961 ccgcatcaaa gtcaaaactg acatctttat cgttattctt tttcagatct tcttttgtta
     1021 cattcgctat agcatattta tctcctgtct ctctgacaaa ataatccttg atctgttcat
     1081 tgaaaatcaa agctagtcct actaataaca agaggaacaa gaggatattg actagccatc
     1141 tttttgcttt tccttttttt ttcattttct ctccctccag actcatttta ctgtttttct
     1201 tttgctcttt ccaacagccg aatgacacat ttctacaact ctgtgtattt ttttcgtaca
     1261 cctgcgcttt tttctacagg atatttcaaa ttatttttga tcaatttttc ttcaatgatc
     1321 tcatctagat ccaggtgaag gttgtctgcc atcatgtatg aatagatcaa tacatctgcc
     1381 agttcttctt tgattcgttc taattgtgtt tcttttactt cttccggcgt tttccattga
     1441 aaaagttcta acaattcaga tgcttccaaa gaaatagaga tagccaaatc tttttcgtta
     1501 tgaaattgtc gccaattacg ttcatctcta aactggttga ctttttccat actattcatt
     1561 tgcttgcctt cttccaatca cttcttactt gattaatcat accatttttt tacataaaaa
     1621 atagatgatg cttttaaaaa aactcctgtt ttcttttatt taaaataaat gtcatagaaa
     1681 atcaataatt taggtagcca ccatgtgtat gcagtagcgt gtcttcttcc cttgaggctt
     1741 tttgtttttc gatacgttct tcttcccaaa cagacaacgc tactagaatc tctcttaatg
     1801 attttccttc ttcggtgagc gagtactcta ctttaggcgg gacttggtta taggcttttc
     1861 gatggatact ttcatcttgt tctaactctc ttaactgctg ggtcagcatt ttttttgtga
     1921 tcgtagggat ttgcttgctt ctccacgcct aaaataagcg atattgctct tccctttatc
     1981 tggtgtaagc aaagcagtta gcattttgac gatcgtgggt tccgcttttc acttcttatc
     2041 tacttagtat catgaagtat actttcgtac taatactaag tagcggaagt gtcaactact
     2101 ttgtttaact acatagcaaa agaaacagaa gggtgacaac ggtcatcacg cttctgtttc
     2161 ttttgaatat gctgtgttgt tgtctctatc tccgtgtaga ctttcctcaa acttatcctt
     2221 tgacagtaag tcagtaggct gatttgctct ttctagatgc cagatacatt tctacaaaaa
     2281 aatagtgatt ctgttttgaa aattcgattt ttagttctgc attttcgtaa acatccaaca
     2341 tttttttcgc actgtataga cctaacccgc catttttttt agaggttttt cctcttttga
     2401 ccatctccga tagcgtcaaa ttcgttggat ttgccttgtt cgctatacta aaacgtgatc
     2461 cctctttttc ttccagcaga ttgatcgtaa tcggactctg atcggctaca cgatgatcga
     2521 atgcgttaga aataaaaata gataaacagc gaataaaaac aaccagatca atcgggattg
     2581 ttttcacttc gacaggaata actacttgga tcgggatttt ctccgattct gctttttcta
     2641 gaaattttaa aaagacaccc ctgacagctg gggatacaat atttgttagc tgttgtattt
     2701 gcggtttttc aaaaatagct gcagaatgat cttctaatat ttctaaaaat tccaacgttt
     2761 cttttttatt ttcctgaaga gtaattttta atgaaaacag tagactttta taatcatgtt
     2821 tgaattcctc tagatgatgg taatattctt catttatttg atacagttga agcgattcct
     2881 gatgttgtct ttcttttact tggaaactga tcaacataat ggaaaaaaac aaagaaaaaa
     2941 aactgatgac tatcgacaaa agagatagaa gcagataatt agatgagcgg aagtgaacac
     3001 ttcccaatac caagtaaatc acgccccagc ttaataaaat acaaatacct ccaaaatagt
     3061 gttcagttgg ataagtaaaa agcaagttga gaaatctcgt ctgtttgtct atacttttta
     3121 ctaatagata gaaaataaat gcgataagta gtgcaaaaaa acttgctgtt ccaagatgtc
     3181 tctttcctaa ataatccatc agatcaaaaa ccagaaaaaa gctgagtcca gtgatagcaa
     3241 aaaaaagatt actgatcaaa cagctgataa acaggttttt cgtagtaaaa taaaaaagaa
     3301 acatcaataa taagccaact aggtaaggaa agctcacttt agggatagga agtaaaagtg
     3361 tcaccaccat caaagctata caaccaaagc tgttttttac tagcagttgt ttcgaaaaga
     3421 ataaatagat acctaaatct aaaatcaaag taaaggtcaa ataaagtgtc actgttgcga
     3481 ccatcttatt cctccattgt tttgtttcaa aatgtacaca tattttttta ataggagcct
     3541 gcatatgaaa aagtatttta tcatagaaga taaccagttt cacagcgaat ggatcatcag
     3601 agaattggtc aatcatcata tcgagaatat cgtgcagctc acttctatct ctcaaatcaa
     3661 tcagttgatc cagttgggca ctattgataa tcacgatgtt ttctttatcg atatcgactt
     3721 gaagcaatca ctcacaggta ttgatgtcgc cgaacaaata cgtaaaaaaa atgcacatag
     3781 taatattgtt ttttcaccgc ttatacgaat tttgcagtag agatcatcaa tcggaaaatc
     3841 cttccgattg gatatatcag aaaagacagg aatttatctg aacaaattcg tcaagtgcta
     3901 gaacagatca attggaaaga acagcagatc gtaaatgtcg ataaaatctt tattgatcaa
     3961 aaaggtggaa gtctcgtcct gtatcctcgg gaaattttat atattgaaag tatcaaaggt
     4021 ttgaaaaacc aagttatggt caaaacaact acagaagata aattagtgaa tacttcttta
     4081 aaacaattga agacagagtt agaaaagtat gcttactttt tacttttaaa atcttactgt
     4141 atcaacttat cgcaattgca gaaaattgat tctgctcatt atgtgttaga atttttcaac
     4201 ggtgactcct tactcgttgg tcgaaagatc tttgaaaaga caaaggaacg tttccatgac
     4261 ttccaaaaaa ctgcttcgag ttgatgaata agagctgaga cgtaagcata gcagatttca
     4321 gggagtgggc cttgaatcgg ctccactccc tgaaatcgtt gatatgattt tacgcttcct
     4381 cttctgtagg agcatctgtt aacgaccatg tgaatgttga aacgtagttg tctacagcat
     4441 aattggatac aggaacaaat aattccactg attgtctccc ttgttccaca ttctctccta
     4501 atgaataaat ccatgtgcca atcccttcat ttgctcctgc agttactaga tctactgcct
     4561 gatctgctgg gatttcgatt ccttcagcgc cagttccaga aacggtagat ggcattccac
     4621 tgctattagt tgcgctattt cgaatcacgg cgtttttgaa tttcaccttt gaaccagtta
     4681 gtttattcgt atcagatgtt gtaccaataa attctgttcg tttgactgat aatttccaac
     4741 cggcataatt tccgctttta tccgttactt gtacgaaatt ctgtacttgt gtttgtgctc
     4801 cagtactgtc cgttccgctt tgtaatgcag catatactgt ttttgctgta cctaacttga
     4861 ttgttccaaa atcaagatct ggagcttggt caatcgtcag taatccggat gttccctgat
     4921 ttggttcgtc aggtgtaaaa ggagtatcag gatcatttgg atcaacagga ggaactggaa
     4981 caacgtcttc aggatttgca gcatctggtt tggtcacaga aatcgttcct tctgtagtgg
     5041 ctgagctctt attctcagca aaaacacttt gtgtacataa taatagactt ccagctagaa
     5101 cggtacttaa tgcaattgtt tttttcattt ctttttcctt ctttctttta aaataaataa
     5161 tccagcaaat aagccaataa gaatgactcc aacaagtatc agccatcgcc agtcaaatgt
     5221 ttctggctga ttttttaaat caatatcctt ttcattcaat tggtccgctg catcatcagt
     5281 tatttcaaaa tcggtatgga gattccagcg tttttctttc caagcaccct tcacaaccgc
     5341 ttgataatgt cccggagcta atttttttcc ttctaatggg acaagtaaat caaaatttgt
     5401 attgggtgct acatctattt tttctttttt tattgaaagg taaggctctt ttgtttcttt
     5461 tttgtagatt tcaaccgatg tagtcaagcc gaacatataa gaagcatttg gattttgaag
     5521 attcgcctta atcacatttc ttccatcgct ttgatccgca taagcttttt ttaatttcaa
     5581 atctggggaa gactcttttt cgctatttca aatcaagatt gctttcactt gagaaaactg
     5641 attgacgaca ccaactgtac ttttgttaga aacgttctct tttttttctt gaaacgtgat
     5701 ccctcctgcg accacaccag ccagctcttt ttctggcgct ttcagtgaaa gtgtctcagt
     5761 gaccgcactt tgaggaggaa cagttatttc tcccactgtt tttgctaagt ttttcatatc
     5821 ataacttaat gtttcatcaa atttactttt tgattctcca tattcgatca caccgtttga
     5881 attcgtcgta gcggagtgga tcaatgtctc aactgttact gatttatctg ttcggttaaa
     5941 gaccgtgtag gggatttcct gtgttttccc aggctccatc cttacattta tatatgtttt
     6001 gttcttatca atctgattag ccggtaattc aaaatctacc gcaaaattga attcggaggc
     6061 atggacaggt gtctgccaaa ggatgaatcc aaggagaagg atcataagta aagagcagtt
     6121 gtttcgatga cttttattcc atattcgatt catcaatcat cctccttgat ctttattctg
     6181 tcggcgcatc tgctaatgtc catgttatct ctgctgagta attaccagct atctgatttt
     6241 ctttggttaa gacaagttta aacgcccgac cgttatttaa atattctgaa taatctgctt
     6301 gcacattcgt tgaattttgt cctctgacaa tttccagttc ttcttcattc actaattgat
     6361 actcctctcc tttcttgaaa tataggacat cctgcataga aaatcctgca tcatttgtga
     6421 aaggctgaga taattttata gttaagatcc acggattttt cgtttctcgc tgatcataaa
     6481 tccataattt ttcctgtata tccatttggc caaatgcttc ttgtgtcaaa ccagttgctt
     6541 tgatctgacc aaaatcgagt ttggaagggg caagaaatga gagaccacct tctactacga
     6601 tcttcgtagc aggtgcaaaa ggcggggcat catgataaac aactggcgta tcacttggat
     6661 tgtgattccc aatttcatcg ttggtacttg gcttgttctg cacaccctta gcagtagctt
     6721 ctcctgcttg gtcgtttaat acaatttcta atacatctcc tgcaaaaagt tgattttctg
     6781 ggatagaaag aacaaattcc cctgtatcat caatagttgt ttctgacaaa acagcttgat
     6841 tttttttcaa tgaaaccaag gctcctgctt cacctgtacc tgtgatcgtg cgagaagctg
     6901 cattgatcaa tgtggtactt aaattagcag gttcaggagg aatcacatcg actgtcgttt
     6961 tggcagagtc cagttctgtc acttcttggc cacctcttac ttttttagca gcaacaactt
     7021 gcacttgatc ctccgttttt aatctctcat cattgggtac ttgaacttcg aacaagccgc
     7081 cttgttcgcc ttctccccat gggttatatc ctgccccttc attttcatct gtttgtcctt
     7141 gcgtgagagc agtaatttct acagatgatt tcgtcgtatc tgcgtaagta atacgtaaag
     7201 tcacttctac ttcgcctgtc caagcatctc ttggctttgc ctcgacacct tcgggaacaa
     7261 cgacatgccc atagattttt ttatctgcat tcgttggcac tcttaaggat tcaatcatcg
     7321 ggagctgatt attggcactg attcgattat aatttttcat tccggcacct gtctgagcaa
     7381 attcatttgt taaacctgca ctagggcttg atacgaaatt gcctaagtcg gtcccattga
     7441 tcgataagtc tgtcatatca gaaaaataat ccgggtcttt ttcaaagtta tcgaatgttg
     7501 cgcctgtttt tcgccataaa gcgatttctg aatgggcgat ctttaaagaa gaatctccat
     7561 ttccttggaa tacccagccg cctatgccat tggtctcgct tccaatccgt ttgttttgga
     7621 aatcaaaata ggtaggagat tctaagtcca cattcaacac atccccactg atgatgccgg
     7681 tcttatcttc ccctgttttc ccgaccatga ctaaataagt tttttcacct gccgtaaaat
     7741 ttaaatcaat atctccagtt gtatctacag ttgctccgga atctgcgcgt atatcgatat
     7801 ttgatttttc tccagtgact gtaaaatcag ctgaacctgg actttctaga aaaccagaag
     7861 cgtcataaaa ttggatcgct tgatttcctt gattgagtct gttcacgtaa gatttgccat
     7921 cacctgtatt tcttaccctc aatgagcctc cattggttac tgtcagcttt tgcgtaccat
     7981 tctcaaaacg aactgcgctg gaacgcccac tctgcttatc gatgtcgata actgatccgg
     8041 ctccttctac gatcaaagaa aggccttttc ctacaaaacg catcccattg ttcccgggtt
     8101 gatcgtcatc tccagccatt ttgaccgaga tttgtccacc acttgataca tggatttgac
     8161 tagaatctcc ttgcaagcga aatccgcccg tagttgctgt attgatggtg attttcccac
     8221 cattcgatac agtgactttc gatcctgaac ctctcatttg gatgattccg cgattgttgt
     8281 cattggtaat attgatcttt gtatttaccg aaaattcgct tcccgaacca ctgacttcaa
     8341 acatgacatt accaggtagc gtatcgactg cctctccttc atcgctaacg ccatctgccc
     8401 gatcataatc aagagagacc tttgaaccgc ttaagatatg gattcctggc gctgtttttc
     8461 cactaccagt ctcatctcct gaatctagaa aaccgtagaa tttccctaga tacggtccat
     8521 aaagttgact accattgatc acattcaatt gatagcttct acaaaaatag gctttacccg
     8581 gagcggcatt cagtccttcc ttcactggtt ggacatccaa cacaccggaa acaccatcta
     8641 atgtgacagt tgcacgagga gcgtaaatca gtcctaattt ggacccatca tacaaatcaa
     8701 gtgtcccggt aaattttatt tctcccgtaa aatgatatct gcttccccaa aaatcggtca
     8761 tataagcaat gataatggca tttccatcga tatttggtgt caatccacct ggatgtgcag
     8821 ctgttccttt aaaattctgg aactcgatcg actgaggtat ctcattgata taaatatggt
     8881 gtgtgccgaa attgtgagcg aatccaccaa aatcaataac gatatctcgt ttgatctcta
     8941 attccctgtc taaagtcaaa ggctgaatca gtcggatctt agttactgat tcgtctgcga
     9001 gaagctgcgc cagttcttct gttgtggcag cttcgctgta cccatccgct gaaacagctc
     9061 ttgccagtgc cgcttcactg ctatcagacg tttgttcagc tacttctgag gtctcacttg
     9121 tcttattttc ttcttgcctt ttattagtag aagcctcact ttgagattct gtagtttcag
     9181 aagtaatcga ttcttctgaa aaagtagtct tgtcaaaact ttgattctct gattgcgttg
     9241 attcgtttgt tttctctaca tcggcaaaaa cggatgtcac catcaagaga gggaagacaa
     9301 acaaaatcga cgcaatcagc ttttttacac attgattcat tctccaccat cctctctgac
     9361 gttttgacaa ttttatttta tcgttttaat ctatttccaa ttgtactttc atatttaaaa
     9421 tatgtatttt tatggaaaaa tttttctatt aggtgtaaat ttcttttttg tacaaaaaaa
     9481 aggctgtgac aaaagtcttg tcacagtccc ttatcccgaa caagcggtgt tctcccgcca
     9541 actcctcggt cacaacctcc attttaacaa taaacctgta aatgtgaggg caatactttg
     9601 attgtcacag gtaatttatc cccttcatct ccatcaacat tcgtcgtcaa ttcttcctca
     9661 tcagctaatg acacaactaa ttgctcacaa gtaaggtagg ctagattttt cgtagattca
     9721 tctactcctt ttaataggtc tggcaatgtt ttaagcgtat cgatcaaaga agaatctttt
     9781 aaataaacca aatggagctt accatcatcc acttttgcat ttggaagtaa tgtttcaaaa
     9841 ccgccgactg agttagttag tcctatcagc aaggtactgc tctcaatttc ttccttcttt
     9901 ccatcaactt ctacgtgaaa cgagtaggat tgtgtggaag ctaactgttt gattcctgac
     9961 atgaaataag ctagttttcc aaatttcgtc ttcttctccg catctacatc attgattgat
    10021 tcagggatag agccaattgc gacgacattc ataaaatagt cgtcatttat ttttccaata
    10081 tccaatggct tgactgattc aatcgaaaaa tgattgatcg cttcctcagg ttctagcggt
    10141 atccctaatg ctcgagccaa gtcattcacc gtacccaatg ggaaaaatcc gaaatttggc
    10201 cgatgttctt gttcagcgat tccactgatt ccttcgttga ctgttccatc tccgcccatg
    10261 acaaacacac tatgataccc ttccgtagcc gcttcgcgag taaagttttt tgcatcccct
    10321 gctttttttg tatgcaagac gaccacttca tcaaacaccg attccaattt tgctatcgct
    10381 aattgctcaa attcctttgc ttgttcaccg cctgaactgg ggtttaccac taataaaact
    10441 tttttcatca ctttctttcc cttctgattg atttctttaa tataacgata gcataaagaa
    10501 aaaaattagg ctgtgatgaa gtactgttca tgaaacattc atttattttt tgacaagata
    10561 aaacatccat actatgaaac tgaggaaaat taaaacaatg atataggaaa taaaagaaaa
    10621 tgataggcat tgtataccta ataaagtaaa aatcttaggt ggcagataaa aacacaaaaa
    10681 tagcaagaga atgtaatagc gtttcttcca ctttttgtta tcagacctta tagcgatcag
    10741 aggaatacca aatgcataac tgaaaaactc ttgatgtact gttaatatgt cacggccttg
    10801 aataataaat gcgacaatcc ccgctataat tagtgtgcct aacaccaaaa cggaaaattg
    10861 atgaatatat tttatataca aatgatccat tgtacttcct gcctttttat ttgtgagaaa
    10921 aacaaatccg tatacgtgaa taacttctag aaataaaaga aatttgcaaa accactccat
    10981 ttatctactt ctacgtgcat tttttgatat tgttttcttt atttaagatt atacagaaaa
    11041 atatctaggg tcgctggatt ctaagtaaaa aaaattttta aaataaaaag aactaaatca
    11101 agtagtaatt aaactactgt tgatttagtt ctaataaaaa gatttagatg aacagtttta
    11161 ttgatttaaa tagttcatat tttttattta taccgcttat ttactacttg ctgtactaga
    11221 atctgaagtg aatgtactca aaacattttc aaagtctttg tctttgattt ttacattagc
    11281 gtctttcaat acttcgccaa ttactttatt ctggaaggta ctgtcactta attttgtgtc
    11341 tgttgcaatt tctttcaatt cttttttgta tttatccatg tcgttgcctt tgttttggtt
    11401 tttcaccatt ttaaccacat aatattccgt agtataagtt gaagcattgg tagaagtgat
    11461 cacatcagaa acttgaccat ctttcaactt aaaggctgct tctttgactt ctgccggaac
    11521 cgttgtagta gtggaatcaa atttcacttt tccgccatct tcttttgtcg tagtatcagt
    11581 tgacttgtct ttggctaatt tagagaaatc gtctccctta tcagcagctt tcttcacatc
    11641 ttttgcatca tcttcacttg ctacttggat aatttgagct tccacttctg gatggaaaga
    11701 ttcccaagcc gtttttaaat cttcatcggt caatttgata tgtttcttta gaccttcttg
    11761 aaaggctaga ctttgtttga tactgtcttt gaatgtttgt tctgtgtaac ctgcagattt
    11821 caattgtgaa tcaaatgaat cacccaattg tttctttgtt tgatcatatt gagaatcgat
    11881 ttctttggtt gatacgtcat ctccatattt atcttcaaat acttgataaa cgatcaactg
    11941 ttgcacagcg gaatctgctc cttgcatttt tttcaagcta tccattactt cttgttcgct
    12001 gattgtaccg cctttataac taacggctgt tttttcaccg gcattcgtac agcctgacaa
    12061 taagccagtg cctagtacga tggcaagtgc taaaaatctt tttttcattt atcaattctc
    12121 ctacttttcg ttttttgcga attgctaaaa acaaaggtgt tcaagatgaa aatcatcaag
    12181 aacaccttta ctaatctgct cgatacgtcc tgaatagata taaggctaca caatccagaa
    12241 agttcgctca gcagaataaa tgtcaagtag cacatcacac cttaatatac tacttctttt
    12301 gttaccgttt ttcaagtcta tcttgcgttc cgtatttaac gtaactaatt cttagaacaa
    12361 atgttatcga ttttgttttt cttcttccgc tgctgggata ttcaaatcag acacttttat
    12421 gttcgatttt ccagacattt ttttgttgtt tttattatga tatattttta tacaactaaa
    12481 aatgaatata ttaaaactac caaaaataac ttttaacgct gtttcattat atgttttttc
    12541 tattttatat aaacttttgg atacttaata ccaaccggtt ggattgtacc aacatgagaa
    12601 tgtgtcagtt ctatttcctg tcgcacttgc ataggcccat actccttttg ttgcatttgc
    12661 tgatcgaata gagtttccaa ctttctcttt tgcaccgtga cgattataga cacgactata
    12721 gtggttagaa tgacctgttt ttctcgtaca agttgtatca ctataataaa cccatcttcc
    12781 agagctatga ttaattgctg ttctagaaat ttcccggtct actggtaaat ttgacttaat
    12841 aatattacct ttagcatcaa aatgaatctc tcctggcttt aaagatttgt aatagatttc
    12901 accgtgaact gaatttgctt ccacttcaga tgacatagcg tttcctccaa caaaacctat
    12961 ccctagtgca caaataataa ctgctttttt cataaaacga catcctttcc tttttgattt
    13021 ttaaagcatg atcttcttgt ttcctatttt ggtcagatat ggatcatgcg tgactacgat
    13081 aactaacgta ccttgggaag cttgttgcga taagatttca actactttat ccttatttct
    13141 tttatccaat gacccagtcg gttcatcggc taaaatgatt ttgctattct tcaataagac
    13201 tctcgcacag gcgattcttt gcttctcacc accagataat gtgtagatag gcgtacttag
    13261 cttcttgttt atatttactt ttttcaatgc ctcatacttt gctgttcgct tatctgaaac
    13321 atttaaattc gaaaacttca atccaatatc taaattaaaa tcgattgttt catattcaat
    13381 caacccaaaa tcttgaaaaa gaaaagatat ggtatttctt tttatcaagc gcttctctct
    13441 cccagttaat tgtttcgtct cttgatcgaa caaatagaat tgtcctgaac tgaactgatc
    13501 attcaatcct aatatattca ataacgtact tttacctgct ccactttctc caacaacagt
    13561 cacaagatcc ccagcatccg cagtgaaacg atccaaatga agaatcgttt tgtttcgaat
    13621 gatttttttc gcacctttta tcactatcaa cggctccaat tgttaacctc cattcatcag
    13681 caataactga cttttctttt ctgtagacaa aataaaaaca actgaaagaa taaaatcaat
    13741 gaagctaaag aaaaaaatat taaaaagata tttaggctct ctttctataa gaaaaaggaa
    13801 gattacactt gtcgttcccc atttgatgag gttcatcatg aagaaatctt tatacgtttc
    13861 aaagagcgaa taaccacttg aacgaaagat agcgattttc cgacaattgt agacaaaata
    13921 tatgcataac atgacatagc tcaacaagaa gaaagaaaag aaagtgagta aaaatatctg
    13981 tatcaagtaa tgaaatgatc tgcttaacac tttgacagct atctcttcag tctgagtata
    14041 cggaaatgat aactgcaagt tatcacgtaa ctgactttct tcaatcagct caaataacct
    14101 ttctttcgac aaagagccta tcttgatctt taacggtgga tagatttctc cgctgagaat
    14161 atttctttcc aaatacatac tgtttttcaa tgtcagtatt tcaacaaccg gataatgttc
    14221 gatccagggg atagaaggaa taaatgtata aatgggttga ttgtttttta taaatagaaa
    14281 tttcggttct ttttcactga tttcttgata atattctgtt atttgcgcca ggtcattttt
    14341 taaatctgta tgtctatatc gttcagggat caatataaca gggtgcgttt ctttttcggt
    14401 tatttggatc aaccttccag agacatcaat caaaggaaat ttcttaagat aattcagatt
    14461 tatttttatc cctctgccaa actgttcatt ttcttcattc aagtaatctg atacattgac
    14521 taatatactt ccgtttttat tcaaagtttc atataattcc tgatctgctg ctgatgcaaa
    14581 acgattggaa taaataaaat ccacgtggtt tttcccgatg gttactggat aaaatacatg
    14641 atagtcctca ccagcgattt cttttggtgg ttcatgggaa acagctaact gtgaagaaga
    14701 aaaaacgata gttgctaatt cgacattggc aacggtcaaa agaagagaaa acaacaatcc
    14761 aaatgtaaaa agaatgtatt ggatatagtt gaacgcttct cttaacgaag cgattttttc
    14821 aactaataaa agagaaatca aagagatacc atatattccg ctgaacaaga aaacgtacat
    14881 ctggaacaaa taaagaaatt gctccttata atacataaaa ataaaaccac caatgattcc
    14941 tgcaattatg aatgtaataa tgattttctt tttccccaat aaacaccaca atacttgatg
    15001 taatgaaaag tcattattca acaataaact gatttcttta ttcatcaata agaaaaagga
    15061 tgataacaaa aggaataaaa gaatcaatcc aatagttaaa tacactcgat aattatatac
    15121 gtctgtattt gaaataaccg aatacgaata gctattttca aagtcttcaa aaatattagt
    15181 ggcataatca gtgtgaaatg cttgattgaa tcgatcagtg aatagtgaaa tgacccgttc
    15241 ataggcttct ttttctctcg tcatcaagaa aaattcacct tcaaaatctt ttattttgat
    15301 cgattcttca atggacgtta cgcgaaagga ggtattagaa tagggtacct tctcgtgaga
    15361 agatttgaca tccccttgat aatacaatgt catttcaagc tttggctgta tcttgaagtt
    15421 ccaagatgta tctacttcat tggattcatt tactgttttt ttcatataag aaagctcagt
    15481 ttctgatgag acattttcaa ataccatgat tagctgctca tattcttctt gcccaataaa
    15541 atgttgtggc aatcgaatcg gagtataagt atctgtttga tggaaaaatt catttgtccg
    15601 atagagtacc tgtttattta tactaaccaa ggcaaaacca ctcatgatac cggtcactat
    15661 gattgtgagt aaaactgtga actttttttt gattatcacc actctccctt acttaaatga
    15721 ttctttgata aaatcatacc gtttttcatc aaaaaaacgt atctatcaag tgtataggtc
    15781 atgtagaata aatctatata ctgtagaatc gaaaggagaa gaagatgaac accggagaaa
    15841 aaatacgaac ttaccgcaga aattgtaagc ttacgcaaaa agaattaggc gaaaaaattg
    15901 gtgtttccga taaaacgatt tctagttggg aaaattctcg tacaatgcca gaccttgaaa
    15961 tgctgtcact tttacatcat actttaggtc tgccgattga ttttccttct attgaatcag
    16021 ctaccgaatc aatagaacca acattgccag atgaacctct tgttaacaag aaatcttatt
    16081 catcaaaaca acccttctca ctcaaaaaga cactatcttt ctttctgctc gtcttttgtt
    16141 tggtctatct ttttcttatc aattatcaat acaaaaatga aacgatcgat cgattcaatc
    16201 cttttttgaa accacaaatc ggctatacca cactccctgt aggatacgtg gacaattcca
    16261 tcgaacgttg ggtatgtaat gatatctttg gccatggtac atggctgtct tttcacgctg
    16321 gagaggtaga aaaagagaaa aaccatgctg taatcaaaca caaaggaaaa cacgtcatga
    16381 acgttcgcct gctcacttgg gaagccattc cctcagatta ccaagaaatc ctcagccaag
    16441 actatgacga cgccttaaaa agaagccctc aggagccaga taggcattaa gtaggagatg
    16501 aacgtagaga tagaaaaaat caatgcacat gatcttatcc aaaaaacagg ggtacaaatt
    16561 aattgaaaaa gccttgagat gaaagttcct aaataaaaaa gttcagaatg ataggtattt
    16621 ctggcttata gtataatatt tacgccacag cctcccaatg attctttttg gaatcataat
    16681 caaggatgga cattcacaaa aatattttgc tcattcgatc cgaatagatt aacgaccaat
    16741 ctagtaagta atatagattg gtacgtagtc aagctgcaca taatttagat caattttagt
    16801 tcttttttat atttctatga tctgctcatt tacttttata tgatggctta cagtaacata
    16861 aataaatatg ataatcgctg gtagtttatc caagagtact caataaaata caaaatggat
    16921 tgttcaagcg cctatcataa tgataaaatg aaacaaataa acgatacaag gaggaagaga
    16981 ctttgagtaa tggcagaaca attttttcat tgtaaaaatt gttcagttgt taatctatgg
    17041 gatttcggta gcatgggcat ttttttatag aggaatcaca ccaacctggc cgttttatct
    17101 cttgttagtg ggaatattag taggaaattt tgcccctctt cactatcgta cgaacttttt
    17161 tccaactgat tctggccttt ttcttaaaac aaagacgcga aaattagaaa acattattga
    17221 aatgacaatt acctgtataa tcattttctt agttatattc ctaaacgtct tctaataaga
    17281 atctcttaaa attagcttgt tacagttagt tacctagttt atataacaca gttatcttat
    17341 cttccttatc aacatctttt gccaactctt tgtcttaaat tcgaaacata taagcagagc
    17401 tacgaacacc aagactgttt cggctctgtt ttttgcatca aattcactct tatatagctg
    17461 ataatctcgg ctctttaaaa gaaattattt tcgcttcatt ttattataaa aaggctagga
    17521 accttgatgt tatcaggttc ctagccttta tttaagtatt accccacaga cccttccata
    17581 tagattttta aattacacac tagtttaaac taaaacaaac aaggaaaaac ttaccattta
    17641 atcaaaaaat tagctcatat gaatatatta gaatgtaaat tagactggtc aaaatctggt
    17701 caaaaaagag gacgaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt
    17761 ttttattgga ttattccctt gttcgatata gacccaaatt gatctatcaa taattatcaa
    17821 actgagtcat atagagacaa aaatttcaaa aatgacctgt taaatggtca tcgaatatca
    17881 tttaaaatca atacgacgga gtcagacacg gagtcaaaac aagcccgctg agagtaaaaa
    17941 atatacagtc ccataggtaa agtgccacag gactgtatat ttttttattt gagattacct
    18001 gaaatgattc catttaattt ttatctcatt ttttcctact agttagtatc aaatactctc
    18061 ctattttctc aataaactat tttgggttac atggtatctg aaacagctaa aaccttgtca
    18121 ttatagcaaa aaatcacttt atctccgttt catttcagat acatttcact taagcggatt
    18181 ccaaaaaaac aaaagaaaaa ggaaccccta gttagcctat gctttttatt ggttcctctc
    18241 aaaacacggt catataacaa cggggtgggg taaatgaatg aaaaaggtgg aggaaacatt
    18301 attcaatagc tgtcttaaat acttcgttat aaaatgtgaa caaataaaag acatctatcc
    18361 ctattttcta cacttccact tgactaccat ctttgaatcg tacaattttc ttaactcttc
    18421 tcgtttacct caattcattc tcaagtggaa tcaactcatc atctaacatt ttacgccatg
    18481 ctcgcttcat ttcttgtggg tatttaaatg gcttcgcttc tggatgtttg gctttatatc
    18541 cttcgtaatc cttactgttg ataattgctt tcatattagg aattggatct tcacctggta
    18601 gatattgcag attagaagca tgtaattctt tctcagaaac aaaccactca ttggaaaaga
    18661 catgaatcaa atcatcactc gcttgtgtaa aatagcgacg tttaatgaca aagatatctt
    18721 cattactatc taaagtcccc acatcaaatg catttaaaat ttgtcggtaa acttctttga
    18781 ctccttctgt tttattcaat ttagccaaag ctttttcaat ttcttctcgt gcatctgaac
    18841 tattcgcagc ataagttcct agtaattgat caatataagt tgaatcaata tcatacaact
    18901 tagtggtatt ttcactataa aattcgatcg ttgaaaaatc ttctccttct ttttctggtt
    18961 cttcctctat taatgaaccc ttcacggtct cgtacacgcc aatttgttct tccaaaagtt
    19021 gaatttgatt gttcaaagtt ggagatttca ccatgtcatc attgtaatcg tcataagtca
    19081 ctaacgattc ataagcacga ttcaattctt gaaatgcttt gacgtactcg atacggattt
    19141 caagtggcgt atgttcatca atggattcca tggatgaaac ctcttttaac ttaccatatg
    19201 cttgtttgaa tctttttttg gattcctgat aacttggata aatcaaacct gattcttctt
    19261 ttgcttttga atacagtttt gtcgcatcct cgacattctt ctccattgtc gctggcttac
    19321 gaaacgtcac aatcaatcct tttgtcttat caggatacgt acgattcgta cgtgaaaaag
    19381 cttggatcaa tcctgcatac tctagattac gatccacaaa tagggtttga atcgtagggg
    19441 cgtcaaaacc tgttaataga cgatccacta caatcgctaa atcgatttgt ttcccaaatt
    19501 gtttgaattc cgctcttttt cgtgccaaac gattattgat gtctccgtta taacgctcaa
    19561 tgtctgctaa tgaccaggaa gtatcataat actgattata ttcctcaata attttttgca
    19621 tttcttcttg ttgggcactt gaatctcggc tattttcttc taatgaatag gtaatagcga
    19681 ttcgtggaaa atcaggatcc tccatcgttc gtccttcacg aatgagctga ttgggaaact
    19741 cttttgttaa ccaatcaggc tctttcgtca tctctttgat ggcccgataa tactttttgg
    19801 ccatgtcaat ggaactcgtg gttaagattg cagatttcgt tggcctgcca tttcgaaaat
    19861 caaattttgt ataggcatta tctggacgga acattttatg aatgactttt tggatatgtt
    19921 catctgcttc aaaaacagct gggtccaaat aactttcttt tttgacaggt tccatttgat
    19981 caatcatacg attgatctgt tctgatgaat actctgcata tgtttctact tcttttaatt
    20041 tccgatagat tttattctct agtgaagtcg gctccacggt gttttcatgc tctacttgaa
    20101 atcctaagac agagccatct tctagcgcat tcttaatggt ataggtatgc aagacctctc
    20161 catactgatc atgggttgta cgtgccaatt gccctttggc ttgtttccga ttctcaggaa
    20221 aaatcggtgt acctgtaaag ccaaaccaag tggatttcgg aaacattttt ttgatttctt
    20281 ccatattttc agcacttaac gctcgatgac actcatctac tacaaacacg atatgttggc
    20341 ccattaattt ttggaagcga ttggttcctt ttttctcttc ttgtttcttt gcatatttca
    20401 acgccgcatc tagtttttga cgggttgtaa tgattacaac atttgcattg gcatctgcca
    20461 acagggtttc acttaattct ttggcacttc ccgttccaac gatcaagcta ttcgctttgg
    20521 cgttcccgga agaaatccca gtattaaatt ccgaagcaaa ttttgtaaac tctgtggtgg
    20581 tttgattatc taaatctttg cggtccacta acatgatcgt tcgatcgatc cccgattttc
    20641 gtgctaaaag cttagtagat acaaaactag tcaacgtctt tcctgaacca gtcgcatgcc
    20701 acacataccc tgattgatgt ttatttgcgg caataaacaa ggcttgaatc gcatgtactt
    20761 gataaggatg taacaccatg agggttttat tgtcttgatc ttcactgacg attgtataat
    20821 ccgcaatcaa acgatgagca tccgggatat ttaacacttg tttacaaaac tcatataagt
    20881 tttctacttt ttcattgtct ttcgttcgcc aactaaataa aaacttaggg tgcaagtctt
    20941 tcggtaaggc atttgcaaaa taccgagtgg tttgttcatt ggaaaccaca aacaactgta
    21001 aggtcgaaaa gatattgttc cgaaacatac cttcttctgc atattttttg atttggttaa
    21061 atgcctgata aacaccatct tttgcagtta cttgtttcag ctcgatttgg acaatcggta
    21121 atccattgat taataaggtg acgtcaaaac gtcgatcccg tgcttctatg ttacttccac
    21181 gttttgcaat ttgatggacc acttcataag tagagattcc tccaccaatg tcttgattgg
    21241 aataaaggat aagtgagaca gaacccaatt gcgaatcttc ccgttcaatc gtgatccgag
    21301 ccatcccatt ttcacctttt aaccatttcg cagcatcaaa tggggttttc gttcgcagca
    21361 gtaattccgt tttgatcgtt tcaaattctt tatcggtcaa aggaaaatca ttcagttctg
    21421 cttgattatt tgagataatt ttttggcgta aattgaccca aaggtcttct tctgatttta
    21481 gatccggacg atacgtccac tgattatgcc cttctccaag tacacgaatc aactgttctt
    21541 cgacttctgc ttcctcacgg tgactaattt tcattcttct tccctcctag acaaacatct
    21601 tttgtaagaa gctttttttc gtttctttta gtaaatctaa cttacgttga tgaagagcga
    21661 tcgtatcatc tagctgtttg aagaaagtac cgattttttg ttgttcatcc tttacaggaa
    21721 ccttaacact gatattctca atatcagaac tgttataaga aggcaatgcc cctacttggg
    21781 agtatcttgg caaatttata gtttcaaaca atattttacc aaaatagata tcccaagtat
    21841 tattaaataa ataagccatg gtattgttat ctattaagaa agggcttgtg accaaacgtt
    21901 ttctattaag cattattgct gcgccaactt tagcaaatat aatcgctggc acatctttta
    21961 ttggcttcca ttttttacgc tcaatttgct cattagatac ataatgattt gcatttctca
    22021 tttcatactc attaccaatg ttattcatgt cggaaacttt aaaaaatgga gtaccttcag
    22081 aaccaccttg ctcggcatca ggaaatccaa ttcccgattg agttttacct aattctccca
    22141 acttacgctc ttcccaatct tccgtaaaac caggaaaccg gatttctggc acttttgctc
    22201 cgttttcagg gaacattttt tgtaagaatc cttttttcgt ttccttcagc aaatctaact
    22261 tacgttgatg aagagcgata gtgtcgtcga gttttttgaa gaatatgccg attttttgtt
    22321 gttcttttaa atcattggga atatagaata ctgtatctga aacttttttc cagtctgaac
    22381 gaggcatttt tgttccagat gtatcatttg cagccttttg atatctatca gcttgaataa
    22441 gagaataaat aaagtccgag tcgctcttct tagctctaaa aacccagaaa tccccaatcg
    22501 ctacgcctgt aaaagttgcc ttgagccaat tttttaaata tggacgtaac tttccatata
    22561 gaatatcatt tggtaaaaat tcaatccctt ttctattatc aaatttctgg ctcacatctt
    22621 tattcagtct accttctcct gccacgatat cttcaaattc aacttttgga agtctactgg
    22681 agtttgtact tttattaagt ctaacaacta aatcaattaa cttacgctct tcccaatctt
    22741 ccgtaaatcc tgggaaacgg atttctggtc gtgtatcatt gctcatgttt gaacacctcc
    22801 agcgcacctt gtaaccacat ttcgttttca ggtgttgttt gcagggaaga gatagcttct
    22861 aaaagttctt tttctagcac ttgctgttct tgtcgtatct tcttgatgtc atttccgaca
    22921 tgaaccatat caattggttc ttcttcttcg aaagtatcta catagcgtgg gatatttaag
    22981 ttatagtcat tttctttgat ttcatcaaag gttgccaaat gagcgtattt ctcgacatct
    23041 tttctttcag cgtaggtttc gaggattttt tgaatgtttt cttccgatag tttattttga
    23101 tttttccctt taacaaattc acgactagca tcaatgaata atacatctcg agtttgacga
    23161 ttcttcttca acacaatcac cgtcgttgga atcgatgtcc caaagaacaa gttcgcaggc
    23221 ataccgatca cagcataaat actgccatct tctagtaatt tttgacggat gaccccttct
    23281 gcagcgccac ggaataaaac tccgtgtggt aagacgatgg ccatggtacc tgtttccttc
    23341 aaatgataga acccatgaag aagaaacgca aaatctgctt tggattttgg cgctaatttc
    23401 ccataacgat taaaccgaga atcatctaag aaagtcgtat ctgctgacca attagccgaa
    23461 taaggtgggt tcattactac tgcatcaaat gtgtaaggtt catctgttgg ccagtcctta
    23521 ttcaacgtat ccccattgcg gagattcatt tcttcggcgt cgacaccatg taaaatcaag
    23581 ttcatttttg ctagattgta tgtcgttgta tttagttctt gcccatgata tttaacgtta
    23641 tctgggtgtg ttaagtagtt acgtacgttt aacatcaatg aacctgaacc catcgttgga
    23701 tcaaaaacac taaagaatcg tcgttccttt tgatcgagcg ttacgatttg cgccatcata
    23761 tcagaaacca tatgaggtgt gtaaaattct ccggctttct tccctgcttc tgaagcaaat
    23821 tgactgatca gaaactcata cgcatccccg atcacgtccc catcgtgttc taaaacatct
    23881 acatcattca atttcttgat gacttcggta atcgtcacat ttcgttgttg ctcatctgtt
    23941 cctagttttt ttgattggag atccacatca tcaaataacc cattaaattg attgtaggta
    24001 gatgccaatt gcacaaaggc tttgtttaga tcgttcaatt ggaacgttgc ttgttttgct
    24061 tgatccgcta agacgttgaa aagatactct ggtgcaattg catatcccaa aatatcaacg
    24121 attgtggcaa tcagatcttc ttttgattct tcatctgaaa gtaattcacg atacaacatt
    24181 gtttgtttgc ttactgtgtc atattcctct aaggattcat ctgctaaaag aaccacttgt
    24241 tccaacaatc gatcggataa atatttatag aaaatcagtc ccaataaata atttttatat
    24301 tctgacgcat ccattttact acggagatta tctgccgcac taaataattt ttgatttaat
    24361 tctgcaccca aaaagataca ctcctatctc ttatttaaag ttgctatata ccctcttatt
    24421 ttagcatacc cccttttata aaaagcaaaa aaaaaaaaag aaagaaactt attcttgcta
    24481 ataaactacg cgaaaggagt ctaacgttgt ttgatataac ttagactgat cgttaactta
    24541 ttttttatat ttctacatag ttatttttag aaccatttca gatacatatg aaacaattac
    24601 atatgatttt ttcataaaaa aacagtactg tctagtagta taaaatatac aaatttctta
    24661 aaaatttttt cactaaaatc actacctgaa acagtctaaa acacttatat atcaacgttt
    24721 aatgaaacta tctccgtttc atttcagata caaataaata tagtcgggct ccaaatccga
    24781 aaaaaaatac ccccagtagc ttatcctaag ctactggaga tgtataagta cggtcatata
    24841 acaacggggt agggtaaata aatgaaaaag atggaagaat cattattcaa taactttttt
    24901 aaatacttcg ttgtaatcag ttacctgtcc gttcttaaat accacagaat aatctttttt
    24961 cccattttca agtaaccgaa gtggaatgtc tttaccaact tgctctgtca ctgcattact
    25021 gatacctgtt agattagcta ataaatctga taaagattga gcatctgtag aaatctctgt
    25081 atcagtattt atcgtgattc ctttatcttc atttacaagc ttccaagtag gtggtatagc
    25141 tgtgtatgtt tcgatgaatg aatcaattct ttcatctatc gtcttcccag tatctacttc
    25201 tgtctcatta ctcttagatg aatcgattct ttcatccatc gtctgctccg taactgcttc
    25261 tgtctcatta ttctcaccgg aaactctctt cacacccaaa cttatatatt gtccatcttt
    25321 agtgtgcata gttaaaattc ccacgctttt actaataaat tcactataac cagttctttc
    25381 aatagagact tcaatgtatt tcacactatc atactcaaaa gaaaaataga catgtaaaag
    25441 cattttgttg tttacatcta cataataatc ctttgactct acttgagacc ttcctatacg
    25501 gaatacagct ttactgtctg atatctctat accagcatcc ttattattaa tctgccaatc
    25561 tccaagtagc tcttctggca agctagtagt ttcttgtgaa cactttacca cttcactggt
    25621 agaggtcgaa acattcacct ccgcactgtt agaagaattt tccaaggaat caggagcctt
    25681 agcacaacca acaagtcttt atatattgtg cagccgatat tttcttcatt cagtacaccc
    25741 ttgaaatatg cagtgttaga taaagcagtt cgtcctgatt tgctgaggca cccatctctt
    25801 cttgaacgta ctccttgatt ttcaaggccg cccgatactc tttcggaaaa cgctgcttca
    25861 ctgaagccag caaaaaatca tccttctccg gcaactcttc cttcttaatc attcgggcaa
    25921 taaaaaactg taaatgcgtc acaaatctta agtaaagcat cgaatcttta tcaacctttt
    25981 tttcgggaaa cagatatcct agcatagcca agatatcctt tagtgctctt accgagagca
    26041 tggtttcttc catatttgct tgttcacttt gggcatttac aatgtgaaac gcaatgtttc
    26101 cagcctcctc ttctggcaac tgaacattca tttttttgtt gatcaattgg atagcatagc
    26161 agccgatctc aaattctttt gggtaatact tttgaatttc aatcagcagg cgattttgaa
    26221 aaacaatgcc tttttgactg cgttcaatgg catgcttcaa gtgatcaacc aaggtaaaaa
    26281 atagactttt attcagctta aagtcaaact tggcgttggc ataatcgata attcgcttga
    26341 cgcaaataat tagatcatcc ggagcagcct caaacagttt aatgtaatcc ttttttagag
    26401 catcagaaag tgaatctaat ttaaatactt tttggatttt gtcagccgga accaaatcgc
    26461 ctttctttag ttgaaatcca atccctttcc ccatcaaaat tacttctttg ccttgcttat
    26521 ctaagcaaag aattaaactg ttgtttaacg ttttaattac tctcattaga ttcaccgttc
    26581 tctctaagct aagccatttc ttgcgattac tttttgatac caaaagaagc tttctttttt
    26641 tattcgtttt aattctttaa gattctcatc ggttcggtca acatatataa aaccataacg
    26701 cttattgaag ccttgatggg tactaacaac atcaatcgct gaccaaggta aataaccaaa
    26761 aacatctaca ccatctgtta aagctgcttg aatagccaga atatgtttgg ctagataatc
    26821 aattcgatcc tggtcattaa ttcgtctatc ttcctcaact atgtcgggtg ccccatagcc
    26881 attttcagta attaaaatag gtaaatcata gcgatcgtac aatttcctca atgttaatcg
    26941 tagtccagta gggtcaacta cccagccata tggcgtttta tctacataag gattttcagc
    27001 tgcccggtag acaccttctt ctcccaacat gatctgttga tcccccgctc tagcggaaac
    27061 atctgatccg tcatttttgc tggcagcgat ggtggcagtt gaataataat taatcgcaat
    27121 aaaatcgggt ttaccggagg ataaaattgc ctgatcctct gcctcaattt taggatataa
    27181 tccacgatca ttcaaatagt tttcaaacaa ataattgtat tttccccgaa ctgctacatc
    27241 taagaaagac cagcctctca atgtttccca attatgggct gcaattgcat cttctggact
    27301 ggaggtagct tgatacatag ccgttaaatt gattgctgga ccgatttttc ctttaagatt
    27361 caactgatga tacaagtgaa ttactctagc ttgagctaat aaaacatggt gattaatttg
    27421 aaagagttct ttttttgaag gcagctctcc acttggtggc aaaccaatcg ctccaggatg
    27481 aaggatcatc gtgttttgct cattaattgt cagccaatag ttcaccttgt caccatactc
    27541 agtaagcaat acctgtacat agtccacaaa ataatcgata gttgctcgat ttaaccaacc
    27601 gccctgctcc tctagaaaat aaggtaaatc gaaatggtac atggtgacaa tcggttcgat
    27661 tccctgattc aggcattcat caattacttg atgataaaaa gaaattccct tttgattggt
    27721 tttattattt tcaatatcca taattcgcgt ccaagcgatg gaaaagcgaa aagcttttaa
    27781 gcctaattct ttaaacagct gtatatcttc tttatagtga tggtaaaaat ccgaggcaac
    27841 ttcaaaatta gctacccctt ctgtatgctg atacttgtca ataatagacg gttgtttccc
    27901 atcctcctga taggcaccct ctgcctggta ggcactaatg gaggcacccc ataaaaactt
    27961 ctctggaaat gctgaaagct gtttgtattg cacaaaaatc ctctccttaa ctaatttgca
    28021 tcaatggttc gtgttccttt aagcttccgc ttgcttcact aattcctgcg taattttcac
    28081 tgttggtcac taccacaatc actgtatcat cgtagccagc gtttctaatg gcagcgaaat
    28141 cggcgttgat taataattgt cctgctgaca cctgatctcc tgcttttaca aatacttcaa
    28201 agggttcccc ttttaaattc acggtgtcga tccccacatg gatcaataat tcaatacctt
    28261 ctttagaacg tagaccaatc gcatgtttag attctaaaat agtaatgact tctccctcaa
    28321 caggtgaata aatgctgttt tcttctggat gaatggctac gccctttccc aatagtccct
    28381 tagaaaagac agcatcgttc acttcagaaa taggacacac ggttcctttt accggatttt
    28441 caacaatgac tgcttcggct attgccgttt gctctgattc atcagaagta tcgtcaaatc
    28501 caattagata agcaatgata aaggttgcaa caaaggcgat tacacacgta ataattgcgt
    28561 gaacaatatt cattggattt tctccaataa aggctggtaa ggctgctaag ccaggggaaa
    28621 caaaggcata tctgactaaa ccgctcaagc cagcatacaa accagcaatt gcaccaccaa
    28681 tcatggaagc aactaatggt tttttcagct tcaaggttac tccatagagt gaaggctcag
    28741 taattcccat taaagcagtg atcccagtgg acacagctag ctgcttcaac tctttgtttt
    28801 tagttttcgc ggctacagca aaggtagcac ctgattgagc aatattagaa gccagcattc
    28861 ctggcccatt gatcatttca gaacccgtac tgctcaattg catagtagcg attggcgtca
    28921 ttgcccaagc tgtacccgta accaccaaaa atggctgcaa accacccatc aaaaatggaa
    28981 ttaaccaagc tgctttgccg ttaatccatt cagcccccat tgctataaga tcgttcagca
    29041 acgttccaaa cggtccaatg acaaccaacg ctaaaggccc cataattaaa aataccagca
    29101 tcggcttagt aaagaattta ataaacgaag gcgaaattcg atccgcaaag ggctctacat
    29161 aggacatgat ccaaacagta aagataatcg gtaaaactga tcccgcataa tctgcagcta
    29221 ataccggaat tcctagaaaa gaaacggcat cgccagtaga aaaaagctgt gaaatatttg
    29281 gatgaagcaa aatgccagca acagtaatcg ccaaaattgg gttgacatca aactttatgg
    29341 ctgccccata ggctaatagt actggcataa aataaaaggc tgcatcagca atagtattca
    29401 aaatgatgta agtttgacta ctgtctgata gtacaccagt caaagtcaag acggccaaaa
    29461 tggcttttac catcccggca cctgttatag ctggaatcat cggtgtaaag gtggtagaaa
    29521 tgacactaat caatcttgaa ataatacttt cttgattgtc tgaagagggg ccctttttaa
    29581 ttgaagttcc cacttccttt tgaatttcct tgaaggctgt ttggacttca ttgccaatca
    29641 ccacttggta ttgtccaccg ctatccacca cactaattac accaagtgtt ttttctaagg
    29701 ctttcgtatc ggctttcctt ttatctttga gttcaaaacg cagtctggtg gcacaatggg
    29761 ttaagctgac cacattttct tttcccccaa cctgttgcaa tacatttctt cctacttctc
    29821 tgtaatccat tattctctct ccttaaagca gtaaaaaaga ccaagtcaaa ccacgcccca
    29881 atcaacattg aagtgttagt ttgtcttggt cttgcctgca taatcagtaa catgccaata
    29941 acgttatttt gctgtaatcc aataatagca cattatgata gcgcaatcaa cagggaattt
    30001 aattttttat cttttcgttt gaccgtatag ggtaatataa cagttagatc acatcaacta
    30061 gggtatatct gcgtatactt actgctaaaa taagtatatc taatattaac tataccagta
    30121 aaaccattcc tacataacca gcgggaaatt cccaaaatcg tgaaagcatc aaaaatgcat
    30181 ataacggatc acacaacttc aacaattctg ctcttgggaa aaattgatga atttggtgag
    30241 taaaggatgg aataaacagc attccaacaa tataggcaac aatagtgata cttgtttttt
    30301 tggtaaaaat cagtaagcaa tagccaattt caatcattcc gagatataaa ggtatcgata
    30361 gaatgatttg ggctagtatt cttaaaaatt aactagcaaa tgtttaaact gatttatttc
    30421 taatctacat gtagtaagta tttcaattcc accaattatc aataaaaata ccaaacatat
    30481 ccataataat tttttctttt tcatttcttt tatattgtta taacagtgaa taacataaaa
    30541 attcccgaca atcattgtaa tatttttttg tcacctgtat tagtatttaa tttataggaa
    30601 actataaaaa ctccctagtg aatttacacc tttgggagtt cctgtttgga cggtatgcat
    30661 aatacattta aatcaattta acattaacac ctcagcatat ggtatctcca catatatacg
    30721 gtctttcttt ggatagtact caatatttat gttgatagca cttccattgt ctaatatagc
    30781 tttagcccgg tatgtgttat ctccattttc atgagtaatc gtcacatcat cacatgatcg
    30841 atttaagttg tactgttctt gtaaaatctg tgttaccaat ggttttgatg acttctctaa
    30901 tccagatgta cctgtcattt ttgaaaaaat aatacctata atagccaaga caacaatacc
    30961 tataatgaca aacttcttgt tcatatttac tttattcaac tttttatctc ctatctccaa
    31021 aataatttgc tcttatccct cttatcagta cattgacatc cctaaaagta caccaaagat
    31081 tgctccagct acccctgcta tcatcaaaat cgtacccatt ttctcatctt tttctcgata
    31141 taagtagccc ataataacag caacagcacc aaatacaaca ggaataaatg ctaacgatac
    31201 taccatagaa atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat
    31261 ttgttccttc atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt
    31321 tgtctcatct gtttcttgta gtgctccaca aaactggcaa tacttacttt catctgttat
    31381 ttctttgcca cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat
    31441 tagttaactg tttactttat taaatacatc agaaaacagc tcattcattg gtacacttaa
    31501 tatctcagaa agcatcttca tttgataggg tttaggaatc gttctccctg tttgccacga
    31561 acttacacat tgctgtgtaa cattcatttt ttttgctaac tccgtttgag aaagtccttt
    31621 ttcttttctg tatcggctga gattacttac ttttttcatg attctcccct cctgttttat
    31681 tatatacaac aatatgatgt atttcaactc ataaaatata aaaaacttca aataccatta
    31741 caaatacaac aacttgttgt actatactga gatgggggtg tattaatgaa acagaaacaa
    31801 tatgcaaagg tcattagaga aaagcgaaaa gctctcgggt ggacacaaaa agaattagct
    31861 gaaaaaatct tctctacaca acaggcagta gcaagatggg aaaattctgt aacagagcct
    31921 aacctcgata gcttaacagc tctttctaga gccctaggaa cccctgtaag ccattttcta
    31981 gacaatgttg tcgtagatta tgaggaagag tttttggctc tctatcgttc tcttagcact
    32041 gaagatgcag ttcgaacaat tgactatatg aagctattaa aaaggcaaga aaatgaacgc
    32101 aatcagctat tgaaagattg aaaaataaat aacccaccga actttaacgg tgggtgtatt
    32161 gagatgaaat aagattaaga gctatggata acctgtctag tttaatacaa ttgggtcttt
    32221 tctcttcctt actctccgtc catcatctct tgttacactt gtaaattgat acagaggaac
    32281 tatcccagct cctgataata tcaattcttt tattgtttca tctatccctg cccctttcgc
    32341 taaatatatt aaaaaactac tacttgcttt cacattgtat agtttcttaa tatccttaga
    32401 agctcgttca agagtgaatc cttgtttaac aaagtagcct ctgtttttta ttaaagcatt
    32461 tttcacgctg ttatccccaa cattacgtag gcgttcacaa acagtgttaa taagttcttt
    32521 ctctgtcatt agatatgtcc cttgccacga taagccctgt aaaacttcat gtgcttcatc
    32581 taaaatcaat tgtttttcct tgctgagttc tgatcgggaa ttttgaggaa atactctttt
    32641 agcctctttt tcgttaaaac atatcttaac ccattcataa gaaaaatatt gatatgtaaa
    32701 atgaattttt tccagaagtg gaaggatatc ttcattcaat ttttgaatca cagaagttgc
    32761 attaaaaacg tctaatcgat agacattgct tctcttatga ttaaagtttc ctaacgcttt
    32821 ctcttccttt aacctattta ggtattcgag catcttcaaa ggaacatctt catcatctaa
    32881 tttttttatc aatcctataa aagtcataag tgatagtaac ttattacatt tatctatgtc
    32941 ataagtttta ccatagtaag aactcatttt tttagctaat tgttcccccg acaaaataca
    33001 agtcacactt tccttactat catcaaaaaa attaacatca gaaagcaaga catcatagac
    33061 acgtcgcatt tcctctagat aattccttat tgtcctgaaa agtttgtctt tcattgattc
    33121 aagagtgtca aaaagtactt ttgattcctc tttcaatttt cgaaaatgtg taggatacaa
    33181 gtctaggttc tctaatagcc aattaaatgt ttctacccga ctgtctttct ttaaaattag
    33241 catcacaact ccaataaaat tttcactgat atcacaatta ctggaatgac aataaaaaat
    33301 ggaatgccca gttttactgg taaaaatact agcagaggga ttatgatcgt tgtgaaacag
    33361 acatcttaag tttttacttg acttaagtaa tttattcata tcaatggtta acaatctttc
    33421 ataaatctca ttaaaagaca tgtcggagga atcaaacagg cagtctttaa accactgttt
    33481 catttcttct ttgtcgtcat tttttatcaa cttaacaaaa tcggtttcat tgactagttc
    33541 atactctctc cctgaatcac tttgacaatt tttagaacat gtcatggtaa aatcaatcgg
    33601 aagctcagta atatctaaca tgttgtcttc attaattatt atcactgcat ctgacttata
    33661 tcctccaaaa aacattctat tcgaagcatt tacattgtca tcacacccgg ggatgttctt
    33721 tttcaagtat tcgtaaacag caaccatttt accatagtca gtaattgctt cttttaatag
    33781 aaagacaatc ttgtattttt ctagattttc agagtaccga atactttttt gtatcgcaaa
    33841 cgcagaatta tgaactaaat tgatagataa aaccttttct atgcttaagt atctactatc
    33901 atctttactc aaatctacta ccttcccctt ctcatcttta acagtgttat cgacatccag
    33961 aataattact ctggtttcca caaaactctc cttgtcattg cctttattct ttgtcttgct
    34021 tggaataaat gattgtgatg aatttagtat ctctacaaac tcatctcttg taacttctct
    34081 atagttatct aaacacctat ctcttacatc agttttttct ttttttgtaa ctggcttctc
    34141 taataatttt tcttgatcta cataaattgg aatattaatc attgatgttt ccatttgtgt
    34201 ttcctcctta taaaattctg ttaaagacta aaacatacag ataataaaaa caaactcttt
    34261 attactatat gttttagtct tatttgttta ctcaaccttt ataccgttcc atgaaactat
    34321 caatatcaga ttttttaaat ctaatgaccg tatcaatttt tataacaggt aacccgtatt
    34381 gagaaacata ttttctaatc gttcctactg atacacctag atattcactt gcctgatgat
    34441 agtccatata ctctagagtg actccagaaa taatgtcttc tagcataggc tttagcactg
    34501 taattatctc tttcacttgt tgttcaactt gtatagaaac aatgctatca atgatttgta
    34561 gagacatatt tccccctcct ttcgtgatta cttgaacaaa ttttctaaga attatcttcg
    34621 tattttttgc tcaaaataaa agtattttgt tattaaccga ttaatcaaac aaaaaatgat
    34681 taccagttca tcgacataca cataatacct cgataaaaaa ggggtgtcaa cagctttgta
    34741 aaatttattt acaacacccc ttttttgagg tatactaatt ttaggaggtg tggtcaatat
    34801 gataaaacgt ccaccaataa attatttaga acgaaaaaag atactcggaa caaaaataaa
    34861 agctataaga aagagtaaaa aattaacaca accagcattt ggtcttatga ttaacaacgg
    34921 tcaattaatt gacaaaaaaa ctatctacga atgggagaag ggaacctatt taccaatacc
    34981 agagcgatta tcccgaattg ctgatttggg aaatatgagt atagaggagt tagtttgtgg
    35041 caatgtagaa gaatatattt tgggaattat tctttataga gatagcattg tactagatgg
    35101 tataacattt ccagataaaa acctgttcca gcatcttcgt caacagttcc caccagtaca
    35161 ctctaattta gatacatggc tggatagata ttccaaatta gaaccagaga tgcaagaatt
    35221 tattgctaac aagacttgta ataaagttaa aaatgaaaaa attagtcttt tcaatatctt
    35281 aaaaatagaa gaattattca tcaatgctat tgtagaagaa tttgacaata acattctttt
    35341 cctcactagc agtatagaag aactactaga aagaatggta gatgaatggc tacctattca
    35401 attgaaagac atgtcttatc ccgaagaagc tgtgagagaa attactgata atataaacaa
    35461 gctagaacaa acgatttcat caattgggaa aaaatacact aagaaaaaaa tgaagggagg
    35521 tgataccatc tagtggtaag tactccttgt aaactaagag gagatgattt aatggcaaaa
    35581 atatcaaagt acaaaaagaa aaacggtcaa gtggcgtgga tgtataaagg acacattgcc
    35641 accgatccac gaactggtga aaaaataaat actacgagaa gaggttttag tagcaaacaa
    35701 gaagctcaaa aagattatga cgagtacaga catcaaatat tatacggtgt taaaaagaaa
    35761 gcacctgata tgacatttga agacctgtat aatgaatgga taactcatca gcgtaccagt
    35821 gttaaagctt caacaatcgc aatctcagta agatacgcaa ataatcaaat acttccagca
    35881 tttggtaagc ttaaactatc gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa
    35941 tggcacagta aatatgaaag ttacgattat atgagaaaac agactgcaca aattttacgc
    36001 tacggggttg caatgcaata tattgacaat aatcctatgg aaaaaacact tcttccacga
    36061 aaaaaagagt atgagaaaaa tcgtaaattt tactcaaaag aggagcttaa taatttactg
    36121 gatgctttta aagattttgg taacatgaaa caatacgcct tcttcagatt attggcatac
    36181 acaggtatga gaaagagtga agtactcgct ttacagtgga aagacataga cacgtttaat
    36241 aaagaactac atgtcaataa aactcttgct gtagatgaat ttggtaaagt tataattcaa
    36301 tctccgaaaa caagagcttc tagacgagtt atctctttag atactgagac tctttctatc
    36361 ctcaacaact ggaaattaca gcaaaaagaa gagtatttaa aacttggata caatactagc
    36421 tctaaagagc aacatgtttt tacaacagtt aaaaacactc tatacattcc aaacactgtt
    36481 aatgattggt taagatatat tttgaaaaaa tataacttgc ctcgtattac acctcatggg
    36541 tttagacata cacatgctag tttattatta gaagcaggag aatctgtcaa ggtagttcaa
    36601 caacgattag ggcatgaaaa tagtaaagtg acattagaca tctatgcaca tattacaaat
    36661 aatgcaccta agaaaacagg tcaagacttt gctgatatga tggctcatca gtaaaagagc
    36721 tggtcaaaat ctggtcattt ctagtataca ggcaaaacaa aaaagctaga acccttatat
    36781 atcaagggtt ctagctccta taacaggttt acccaacact gccttccatc tcataactga
    36841 tcaatcggtt gagttcgact gcatattcca ttggaagttc tttggtgaat ggttcaacaa
    36901 agcccatgac gatcatttca gttgcttcag attcggtcag gcctcggctc atcagatagt
    36961 agagttgttc ttctgagatt tttgagactt tggcttcgtg ttctaaagag acttggctgt
    37021 tgtggatctc attaaatggg atcgtatcgg atttcgacca ttcgtccatg atgattgtgt
    37081 cacattcgat atgagagatc gaacccgcac tgtttttggc gaaggttact tgtcctcgat
    37141 agtttacttc tccgccgtct tttgagattg atttagagac gatagagcta gatgtatttg
    37201 gtgcattgtg gatcattttt gcacccgtat cttggatttg gtttgctcct gcaaaggcga
    37261 tggagagcat ggtgcctcgt gcgccttttc catctaagta aacacttggg tatttcatcg
    37321 ttgtttttgc acctaggttt ccgtcaatcc attcaacggt tgcgccttcg tatgcttttg
    37381 ctcgtttggt tactaagttg tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc
    37441 aatacgcatc ttttcttgta aagatttcta cgatggcggc atgcagacta ttacttgaat
    37501 aagtaggtgc cgtacaacct tcgacatagt ggatgcttgc tccttcgtca acgatgatca
    37561 gcgtacgttc gaattgtccc gtgttttccg cattgatccg gaagtaagtt tgtaatggaa
    37621 catcgacttt gacgcctttt ggcacgtaaa taaaggtgcc acctgaccat acggctgaat
    37681 tcagcgctgc taatttgttg tcagttggcg gtacaagttt tgaaaagtac tctttgaata
    37741 attcagggta ttctttcaaa gcagagtcag tgtcagtaaa gacgattcct aacttttcga
    37801 attcatcttt catattatgg tacacgactt ctgattcata ttgtgcggaa gcaccggcta
    37861 gataagctcg ttctgcttct gggataccaa tcttttcaaa tgtatctttg attttttctg
    37921 gtacgtcttc ccagtcacga gcgggtttgt cacttggttt ttggtaatat ttgatggcat
    37981 cgaaatcgat gtctgaaagg tcggggcccc atgtttgcat tggcattttg ttaaatgttt
    38041 ctagagattt cagacggaat tcaagcatcc attctggttc gcctttgatt cttgacatct
    38101 cacggatcac ttcttctgtc aagccttctc ctgtactgaa aaccggttcg acatcatcgt
    38161 gaaacccgaa tttatattct tctaattctg gtacgcccat gttctcactc ctcttccttg
    38221 tggtaatgat ggaaagctgc ggtaccatcg ttttccattg cttttcctag tgctttccag
    38281 gcaagtgtcg cacatttgat ccgagctgga aatttagcta caccaccaag catagcagca
    38341 tcgcctaatt ggtcgggatc tttgacttct tttccttgga caagctgtag aaagtctaca
    38401 gttaaatgtt ctgcttcttc tattgatttt ccgatgacgg cgtctgtcat catcgaggca
    38461 cttgccgtac tgatggagca gccactgccg tcaaaggcga tatttttgat gattccgtct
    38521 tttacatcga cttgcaattc gatcacatct ccacatgtgg ggttgttcaa ttcgatctta
    38581 cttgtcgagt cagtcaagct tccacgatga tgcggatggg aagaatgatc caagatcact
    38641 tgacggtata aattgtctaa tttagatagt cccatgctgg aaaaactcct ttgttgccat
    38701 gattgcttca actaaacggt cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg
    38761 agcagtcgct gatacttcaa ggtacttcaa tagcggttgc gcacaatgat gacctgctct
    38821 gacggctacc ccttccatgt ctaaagctgt cgcgacatca tggggatgta acccatccaa
    38881 attgaatgca acgactcctg tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc
    38941 atcaattgct tgtaattttg gcaacacata agcggctagt tcttcttcat atcgatggat
    39001 attgtccatg ccgagttctt gcaaataatc gattgcatgg cctaatgcga tagcgccggc
    39061 gatatttggt gtccctgctt cgaatttcca aggtagttct ttccatgtac tgtcgtataa
    39121 ttcgacaaaa tcgatcattt cgccaccaaa ttcaacaggt tccatttctt ctaaccattt
    39181 tcgtttacca tataaagcac caatacctgt tggtccgcac attttgtgtc cgctgaaagc
    39241 aaagaaatca cagtctagtg cttggacatc aatggccctg tgcggggcag attgagcacc
    39301 atctactacg atgaccccgc cgttttcatg gacaagttca gctaattctt gaacaggatt
    39361 gatgacacct aagacattgg atacatgagc aatggagacg attttggttt tgtccgtaat
    39421 ctttttcgct gcatcctcca tatccaggaa gccttcttct gttagttcga tatatttcaa
    39481 gacagcacct gttcgttttg ccaactgctg ccacgggata acattagaat gatgttccat
    39541 gtaagagagc actatctcgt ctcctgcttt gatatagcgg tcgccgaagc ttctggctac
    39601 ccaattcaag cttgtcgtcg tacctcgagt aaacagcact tctgctgttt cttttgcatg
    39661 gatgaacgcc cgtacttttt ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa
    39721 cgtatggaca ccgcgatgaa cattggcgtt atcgtgttcg taatagtgcg ctaatgcctg
    39781 gagtacttgt tttggctttt gggtcgtcgc tgcattatcc agataaacta aaggttcatc
    39841 attgacgtct tgaaataaga taggaaaatc attgcgtagc tttttagcat cgatcatcca
    39901 ttcaacttcc cttcgattac ttcgactaat tctttccgaa cttgttctac agggattgct
    39961 gttaagacag aaccgaggaa tcctcgaatc actaagcgct ctgcttcttc tttatgcaat
    40021 cctcgactca tcagatagta catttcttct ggatcaactc gtcctacact ggcagcatgt
    40081 ccagcagtta cttcgttttc atcgatcaaa agaataggat tcgcatcacc acgtgcttta
    40141 tcagaaagca tcaagacacg actttcttgt tgggcatctg caccttttgc ccctttcaag
    40201 atgtggccga taccattaaa ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa
    40261 atatgcccga tcgtatgagg ggctttattg gttactcgcg tatcgattcc ttggatttgt
    40321 ctgcccgagc tgattgccac gattttgact tctgcgtgtg caccttctcc tgctaaatct
    40381 gagtcaaagt cagcgatcac atgaccgtca ttcatgacac caattgccca gtcgacagaa
    40441 gcatctcgta aaatgtgccc acggcgattc atataagaag taatattttt tcctaattga
    40501 tctacggttg aatatttgat ttttgaacca gctttagcga tgacttccac gatgatatta
    40561 cctgatgatt ttgctacttg ttctttggtt gtctggaaac gttccagata agaaaattca
    40621 ctatgttcat ctgccacgat caacacatgc ttgaagaagt gctcatcgga tgcgccatct
    40681 tgaatgaata aggactcgag tggttcatcg atcacgacat ttttaggcac atacaggaaa
    40741 ataccgctgt tcataaaagc tacatggagt gcagtcaatt ggtcttcgtt catgtttact
    40801 gcttttttca tataatattc ttggactagt tctggatatt cgatcattgc agtgaacaag
    40861 tcggtaaaaa tgactccttt ttctgctaat tccacaggca gttgttcaaa aatcgtccat
    40921 gaaccttgtt ggacaagcac aggattgtct ttcattgcat caaatgccgg aatcgtgcct
    40981 gtttcactga tggtttgtgt ttctttcaca tcaaataacg accagcgatg gaatttcacc
    41041 cgatcgatat gcggcaatgg cagttcatct gctttcgcta gtgcgtcttg acggaaggtt
    41101 ctcatccaat caggttctcc tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg
    41161 agccagtttt tttctttcat tcttgctccc ccttacgctt cttcttcttt atagtcgatt
    41221 cctaattctt tactgatacc agcgtagcct tctgcttcca gacgtttagc taggtcagca
    41281 ttccctgtca tgactactcg gccttccatc atgatgtgaa cgacatcagg tgtgatatag
    41341 ttcaataatc gttgatagtg ggtgatgatc aatgcaccga aattgtctcc gcgcatttca
    41401 tttactcctt tagcaacgac tttcaaagca tcgatatcca gacctgaatc gatttcgtct
    41461 aaaattgcaa atgttggttc taacatcaac aattgcagga tctcattccg tttcttttct
    41521 ccgccagaaa aaccttcgtt cagataacgt tcagccattt cttctggcat atttagtaaa
    41581 gccatttttt catctaactt tttcaaaaat gccataacag aaattttgtc gttttcatca
    41641 cgtttcgcat tgatcgctgc acgcatgaat tccgcattcg tgatacctgg tatctcactt
    41701 ggatattgca tagctaaaaa taagccaagt cgcgcacgtt catctacttc caagtctaaa
    41761 acatttttcc cgttaaacaa aatttcgcct tctgttactt catagtttgg attgcccatg
    41821 atagcggcag ataaggtaga ttttcctgtg ccgttaggtc ccatgatggc atggatttct
    41881 ccggttttca ttgttaggtt tacgccttta aggatttctt tttcctcgat cgacacatgt
    41941 agatttttta tttctaagac agacatgcat tataccccca aattctcttt cgttctcact
    42001 cattttagac taattgagaa tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt
    42061 tatttattat taaacaattt tgatttctaa attagaatag atataaaaaa gatgagaaat
    42121 aagccattac agacttattt ctcatctttt ttgttccata ccttattttg catcagcctt
    42181 tactggttta acagagccgc cccatttgtc tgtgatccat tcttggactt ctttgcggtg
    42241 aagcacttca atcagttttt tgattttgtc actgtcttca tcacctttac gagtcgcaat
    42301 aatattcacg taaggagagt tgtccttttc aagcaatacg gcatcttcta atggattcaa
    42361 ccctgcgccg taagcgaagt ttgcgttgat tgcaactagg tcaccttcat cattttggta
    42421 cgtagaagct aaaagtgatg ggtcgatcgt atggttgaac ttcaagttct tagggttttc
    42481 ttcaatatta tcgaatgttg ctgtttccag atctactcca tctttgactt tgactaagcc
    42541 agcatcttgt agaattgtga tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat
    42601 tgttgcacca tcttttaatt cggaaacatc tttgactttt ttagagtaca agcccattgg
    42661 ttcgatgtgg acagcaccgg cattgacaaa gtcatatcct ttttctttga tttctttgtt
    42721 caaataagga atatgctgga agtaattggc atcaatgtcg ccttcttcca aagattggtt
    42781 cggtaataca tagtcatcga atttgacgat ttcaagatcg attccttcat ctttcaataa
    42841 tggtttcaca tgttccaaaa tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt
    42901 cgtgtcgtct gctttatttg ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa
    42961 tcctacagtc agcaaaagcg ctgctgctaa tccaaaaatt ttctttttca tatcctacat
    43021 ccccctatat cctattatct tttgtctgtt ttcttagtta agaaatcacc gattccttga
    43081 acgataaata cgattagtaa aataattaaa gtcgcaacga atgtcactgt cagattacca
    43141 cgctggtagc cttcctgcca agcaagacct ccaagtccac ctgcgccgat cgcgccggcc
    43201 atcgcagtaa atccgatcat cgagatcgtt gtaactgtta atccagaaat caatgcggga
    43261 atactttcag gtatcaagac cttccagatg atttcccagt aacttgctcc cattgcatct
    43321 gctgcttcca gtacaccagg gctgacttca cgaaaagcaa tctctactag acgggcataa
    43381 aatggtgctg cggataaaac aagagctgga atggctgctt gcgcacctag catagtgcct
    43441 acgattgctt tagtaaatgg aatgatcaaa accatcagga tcataaatgg cgttgaccgg
    43501 aaaatattac tgatgatcga tacgattcca taaatgattc gagcatacgg tttgtttttg
    43561 cgtccaatag agtaaaggat caatcccaaa actaatccga tgatcgtcac taagaccatt
    43621 gagattaatg tcatatatag tgtatcaagg atagcctgat tcatcgtttc cgggttgatt
    43681 tgtttaaaat ctagatatgt ttctgaaaag cttttatcca cgatggatca cctcaattcc
    43741 tactccttgt tctttgatga acacttctgc ttgatctaat tctttggttt caccagtcat
    43801 caagacagtc aatgaaccaa aggaaccttc tttcacttgt ttgatctttc catacacaac
    43861 gttgacatcg atgttatagc gtcgaatcgc ttgggaaatg actggctcgt tggcatttct
    43921 ttcgctaaag gtcaaagttg ccaaacggcc gcttggattt tctttgatga gttcagctaa
    43981 tagttctgtc gaatcagctt ctggttcgat gtcttgttgt acaaagcgtt tggttacttc
    44041 ttttttcggt tgtctgaaga cagtcaatac gtctccttct tctacgactt tccccaactc
    44101 catcacagcg actttgttgc agattttgcg gatcacattc atttcatgtg tgatcaagac
    44161 gatggtcaaa ttcaatttct tattgatcgc taacaataag tctaatactt cttctgttgt
    44221 ttgcgggtcc aatgcgctag tagcctcatc acaaagcagg atctcaggat catttgccaa
    44281 tgctcgtgcg ataccgacgc gttgtttctg cccgccggaa agttgtgaag gatatgcttg
    44341 tccgcgtcct tctaacccga ctaaacgcaa cagttcttct gcccgttctt tacgtttgct
    44401 ctttggtacg ccagctaatt ccagcggcag ctggatattt tcaagtacag ttcttgacca
    44461 taacaggttg aaatgctgga agatcatacc gattttcttt cggaatgtac gtaattcttt
    44521 gttttttaat tttgtaatat cttgatcgtt tacgatcact tcgccgctcg tgggaagctc
    44581 aagtccattc aggagacgga ctaatgtact ttttcctgcg ccagaatagc cgacgattcc
    44641 ataaatatcc cctttttcaa cgtttagtga aacgtcattg acggcttgga tgtttccgtt
    44701 tttcccattg aatgtctttt tgacattcgt tagttggatt aatgacatgc cattcacatc
    44761 tttctcttat gatttttcaa acaaaaaagc cttcgccctc ttgccttaag caaaaggacg
    44821 aaagcttgaa cttccgtgtt accaccttga tttaccgtta cttcgcaata acagcctctt
    44881 ccagtacttg gacttagctt ctttccgtat actgtcgcgc tgtaacgggc actcccgtag
    44941 taagtttgct tacgctcgct tactctgctc taagaccatc ttccatctca ttttcgttac
    45001 ccattttcag caaacagggc tctcttcaaa cgtccgtgac atgtactctt cttttcaaag
    45061 ctttctcgtt tcatatagga ttgcttatga ttatagcaac tggaagaatc agtgtcaact
    45121 tttttcaagt gattttctga ttttataatt cgtcaaattc ttttggatca acatctttga
    45181 aacttaagat ccacgcattc atttcatctg aatcattcaa gatattgata tcttcaccga
    45241 ttttatcatt aacagaagaa actgtacccg ttagcgggct ggcaaattca ttgaccgctt
    45301 tttccgcttc aacttcgatc agaggttcat ctttttttag cgattgtcct gcttttggca
    45361 gattggcaaa cgtgatgtct ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt
    45421 attcttttcc attaaataag atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca
    45481 ttttatatca gttctccttc ataaattttt tcattgaatc caattgcaac aagctggtcc
    45541 tctcgtaaga tcagtggccg cttgatcagc ataccatctg tcgataagac ttggctcgct
    45601 tttgaagccg taaactcgcc tacttgatct ttcagtccaa gttcccgata tttcatcccg
    45661 cttgtgttga acaggcgacg gattggtact tgactcgttt ctagccaagt ctcaatcgtt
    45721 gaggccttcg gtacttcttt gatcatatca acagtttgat aactaacgcc atgctggtct
    45781 aaccacgctt tggctttttt gcatgttgaa catttcgggt accagtaaaa ggtgtacaat
    45841 tttcttacct ccttgaagat cttgcaggtg cttcattttg gtatctcatc gataatatca
    45901 acccgatacc gatcatgttc cctaaaatcg aagatcctcc ctgactaatg aaaggcaatg
    45961 ggatccctgt taaaggaagt aatccgatat ttgctccaat attctcaaag acatggaaca
    46021 gcagcatcat gatcaaaccg cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac
    46081 acacccgaat catacgatag attaaaataa aatacaagaa aatgacaaat gcaccaccga
    46141 taaagccgaa gttttcaccg acaacggtaa aaatcatatc ggactcacga acaggcacat
    46201 aaatattgct tacgttgaat cctttaccaa acaagccacc ggtaccaatt gccaaaagtc
    46261 cttgggccgg ctgataactc attcctgacg tatcatggaa agggtccagc catgaatcaa
    46321 tacgtgcaaa ctgataagat ttgaagccaa ctttgtaaag caagtctctt ccgccttcag
    46381 tcgtaaccaa gaagatcgtt cctgctccaa cgactactgc caagattact acaggtgcga
    46441 tgatgcgcca agagattcca gacatcaaga aaatcccgcc aaagatcgca agaaagacaa
    46501 gcatcgttcc aaagtcatct tgggccatga tcaatgctaa aaccggtatt gtcacgatca
    46561 agagcttccc aatcagccaa aagtccgatt tcatcgtccg ttcttttact tgcgtattat
    46621 gtttagttac gatcagtgcc atcatcaaga tgtacgcaat cttcatcaac tctgctggct
    46681 ggaaagtaaa cgcaccgaat cgaaaccagt ttttagaccc tgttgaagca gctaaattct
    46741 gatcatagaa tttgagcaag agtcccatta ccactaaccc caaaccataa aagtaaggag
    46801 tcagtttcca gatccatttg gaattcaaat gcatgatgac aacgattgct gccgctccaa
    46861 ctaaatacca gacaacttgc atccctacgc ctttcaagac tgctggattg ttcggatcat
    46921 ggctaagtgc tacatataat gagagcagac caatcaaaca taacagaaag actggtaaaa
    46981 tcacgccata atcaatacga ttatcgttcg aagcttttaa ttttttttcc atgtttcatc
    47041 ccttttctta aaaaccatac tgctgattat tatagcggtc cagttagata atggaaagtc
    47101 tttccataga catttgggaa aaattaactt tccgtttgtg cagttgcttg agcaaatgca
    47161 gtacaaaagc ctactgctta tctttagtgt atcatagaac tttttttgat acatgcaatt
    47221 atctaccaac tgagattctc ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg
    47281 atctcttcgg caatctctag cagctgatca gaaaccagat tggttcgttg gatgaaataa
    47341 aaataacgat ggaaattcaa cggagtcatt ggcacatttt ctggaacaga gcgcttagac
    47401 aaaatcgagc gaccgattcc ttccttcagc aacgcaacaa ttacatcgtt acttttcacg
    47461 atcatcttct tatcttggat attcatctct tcaaaataac gctgcgtgta atgaaaaaca
    47521 ccagagtttg cttctcttac aagccacaat ttgctttttg ggtccccagc gatgactagc
    47581 tggtcttcca tcaaagagta tctttgtacg ccggaagtct ctaatggctt ttcgataaaa
    47641 ccaaaatcgg attcatgttt cgctacttgt tctaatgatt catgagaatt cgcgatttcg
    47701 atctcaaaat gcactttagg aaaccttttg atcagatgtt tcatcaactg aggcaaagga
    47761 tagacagcaa aggtgtggga agcaacgatt cgacatactt cttcttcatt ttgttcattg
    47821 agcaattttt gctgagtttc ttcccattct tctaacaaaa ccagtgtccg ttcatataat
    47881 aagtcggctt gcttagttgg aagcatctct tttcttccgt tacgttgaaa aagatcgata
    47941 ttcaattccc gctccaactg tttgatttga ttcgagactg ctggttgaga taaaaacagt
    48001 acttctgctg ctctggaaaa atttcttgtt tcatatactg ctcgaaaagt cgttaataac
    48061 ttaaacatgg caccacttcc ataacttttt atgataatta ctataaaaac tatttgattt
    48121 aaatatacaa aaaaccatct ataatagaaa tgtacaacaa aacagttgct gatccaacta
    48181 gtaacttaga tgaagacaat cagctgtctg cttgctcgta atcatacatt cctattcatt
    48241 ttacaatgta ttcgttcatc ttggtactaa aatctattaa ataaaaagga gaatattata
    48301 tatgaagaac tttttgaaaa ttattccgat cccgatctgc gggttgatcc ttgggttagc
    48361 ttcccttgga aatctgttta aagactatca ccatgttgct ttaggcaatc taactggcgg
    48421 tatctctatg attcttatga tattcatttt tgttaaattg tttatcttat tcgaacacac
    48481 gaaacaaacg ttgcatgatc caatcatcgc ctccgtttca ccaactttta cgatgtcact
    48541 catggttatt tgtacttatt ttgtttcata tgaaagtatt gcaccaattg tcaaattcat
    48601 ttggctgtgc gctgttatct tccaagtgat ccttgtcttt tatttcaatt atcaccatgt
    48661 tatcaaagct gatctttcaa ttgaagcaat ttatccaagc tggtttatca tttatgttgg
    48721 atttggggtc atcactgtaa ctgccgggaa cttcttcccg cttattggaa aaattttctt
    48781 ttggatttca ttgatctgct atgcgttctt attgccgatc atcatcaaac gtgtcttttt
    48841 cgtaagaaat atggctcatc cgacacgtcc gctgattacg atcgttgcag cacctggttc
    48901 tctttgccta acaggttatc ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc
    48961 attgttcgct ttatctcaag tattgtattt cgttgtgctg tctatgcttc cacgtttgtt
    49021 caagcttcgt ttttatcaaa gctatgcagc ctttacattc ccgcttgtta tctctgcaac
    49081 agctatattt actactgttc attacttcaa cagtttaggt atctatagta gcgtattgga
    49141 tttcttaaaa gttgcggaat gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca
    49201 ttacgtacgt ttcttaatta aagaacatag caaacatgga aaatttgttt ctaaaaaaat
    49261 cgcttaataa tcgattcaat aggttgtgaa aaagctgttc tgcatcaagt aataagaacg
    49321 gccaaacaaa aacagctgtt catgtttttg aattggttgg gcttattacc gcagatgcaa
    49381 gcttttgaac accgtttacc aagaggtcgt aaaagaagtg gccagcttca agaaataaga
    49441 aggaatttac gaaaattgct tctcaaattt ttgtgaaatt tcggcttatt tccgaaaaag
    49501 ctacttctgg aacaccgttt accaagaggt cgtgaaaaag ccgcttagtt tcgagtatta
    49561 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
    49621 aactggcttt tgaacaccgt ttattcgaaa caagaggtcg tgacaagact tttgtcacga
    49681 cctcttgttc ttttgtcaaa atactggttt agtgctacta tgttcgagta tgcttttagt
    49741 atttattgac gaaaggaacc gatcaaatga aatcattgtc acatccaata aaatctgtaa
    49801 aggattcagc ggtccgcgaa atcttacccg gtttactgct ttcttttgcc atcgctgcct
    49861 tcagcaggct tcttgctatt tatctgccac agttaggtgg agcgactatt gctattttat
    49921 tgggtatttt attaggaaat acttttttta aacagcctgt tctagcaatc ggcacaaaat
    49981 ttgctgaaag caaactatta gaattctctg tttttttact aggtgcaact gtcacagctc
    50041 aaacgattgc tcaaattggt ataaaaggaa ttgtttttgt gttactgcaa atgtcagtca
    50101 ctatcatcgg tgcttacttg attggtaaaa aactgcaatt cagcgatact tcttctttga
    50161 tgatggctgg aggaaacgct gtttgtggtt cttctgctat tgcttcgatc gccccttcca
    50221 tccatgcgaa agaggaagaa aaaggacaga tcatcacact agtcaatcta ctgggtactg
    50281 tgatgatgtt gactctccct ttccttggat tacagttgtt tggtggaaat ctcattgaaa
    50341 aaagtgcact tttgggtggc acactccaat ctgttggtca agtagtcgct ggggcaagct
    50401 tacttgacaa ttctgttgtc gaattcgcca tgctatttaa gattctacgt attatgatgc
    50461 tcgttgttgt tgtctatctg tttgaaaaat tcatgcacaa gaaacaacca gctctgtttg
    50521 aaacgccaac tgatacgcag aaaaaacgaa aattaccact tccttggtat gtattagggt
    50581 ttgtgatctt ttgtttggtc aacagcttgt tttctttacc tgtagttatt gaccaatcgg
    50641 cacattttat cagcagctgg tttgagatca ctgctttagc ggcaattggt ctgcgtttag
    50701 actttgcaaa attcatgaaa gaaggtacac gcttcttatc ttatggatta gctgtcgggc
    50761 ttctccaaac agtgatggct ttactattta tttggctgat caaagtttag aatgaacatg
    50821 aaaaaacagt tgtgattctc gcatggaaca atgtccgaat cacaactgtt tttaattttg
    50881 cagatatcct tctaacaaca acaattggcg tttgatttca accccatcta ttgcgtttcc
    50941 catatatcct gtcagttttc cattttgccc gatcactcga tgacaaggaa taacgattgg
    51001 caatggattg gttcgatttg cctgcccaat cgctcgcaca gctttcggac tatcaacagc
    51061 aacagctact tctttatacg ttcggatttc tccataagga atggtcgaca aagctttcca
    51121 gacattttgc tgaaaaggcg tacctctctt tatagataaa ggaacatcaa attcttttct
    51181 ttttcccgca aaatattctt caaactgttc ttgtgtgcgc gttaaaattt gctgattcgc
    51241 tgattcgctt tctgaaattg gctgaaaaga tacagcagtc aatccggatt catctgcatc
    51301 taaccataaa aagccgatag gtgtgtgtat tttcattttg tttgctcctg gtcagtagac
    51361 tggaacttcc tcctttttct ctatccaaaa ctacttgcca actaataaaa attgttctta
    51421 aaagtttgat aaaccgagga aacatggtaa actaaatacg ttagtttacc aaagaatagc
    51481 tgttcttttc cataaaatca aatttaaaag gtgttattta aggtttatta aattttgaat
    51541 gtaaaccata tataaacata cgattgaaag gatagaaacg atgaaagtat caattgttgt
    51601 cccatgtttt aatgaagaaa aaactgttcc tctttttttt gatgaggttg aaaaattcaa
    51661 aggtgcccat gagttcgaat atttgtttat tgacgacgga tcaaaagacg gtacgttagc
    51721 agcaatcaag aagctagcct cagcttatcc ttatgtccgc tttgtctcat tttccagaaa
    51781 ttttgggaaa gaagcggctc tgtacgctgg attgcaagct tctacaggag atttagtgac
    51841 cgtgatggat gttgatctgc aagatccgcc cgaactgctt cctgagatga tcaaccggat
    51901 cactacttct gatgtcgata gtgtcggcac ccggcgttcg actcgtgaag gcgagcctgc
    51961 gatacgcagt ttctttgcga aaaaattcta ccagttgatc aataaaatca gcgatacaga
    52021 aatggtcgat ggcgctcgtg atttccgctt gatgactcgt caaatggtgg atgccgtcct
    52081 agaattaaca gaatacaacc gattttcaaa aggattattt agctgggtcg gatttaaaac
    52141 agaatatatt tcttatgaaa accgcgaacg tgtggctggc gaaacatctt ggtccttctg
    52201 gaaattattc aactactcga ttgatggtat cgtgaacttc tcggatgcac cgttaacgat
    52261 tgcttcattt atcggcgctt tgtcttgtgt cggttctggt attgcaattt tgttcattat
    52321 tttgcgggca ttgttgtttg gtgatcctac atcaggatgg ccttccatgg tctcgatctt
    52381 cctgttcatt ggtggaatcc aattgttatg tcttggaatc atcgggaaat atatcgggaa
    52441 aatcttctta gaaacgaaac agcgtcctgt ttatatcata agagaaacag aaaaagtgaa
    52501 gccaaatgaa ttgaagcctc accaataata tacgtcaaat gaagtaaaca tttttttaaa
    52561 tgaaaaagga ctgtgacaaa agtcttgtca cagtcctttt ttccgaataa atggtgttcc
    52621 agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaag caattttcgt
    52681 aaattccttc ttatttcttg aagctgacca cttctatcac aacctctttc atatcttatt
    52741 acttcttcat tgctgctttt agtgctgctg ctaatgggct ttcttctggt tcttctgctt
    52801 gtgcatattt tttcagcaag cgtcgttctt catgtttggt cattttcttc ttctgctctt
    52861 ttttatcaag cattttttct gtcgttccat cgtatttaca acggaaataa gcaccgtttt
    52921 taccttcgat gatttccatt ttccggtgac attgcgggca tcgatgatta gagacttttg
    52981 gatcttttct tctgcggtag ttgcaatctg aattggtgca gacatagatt ttgccgtcac
    53041 gtgtgttttt ctcgcgcaga ttggccccac attctgggca tttcttttgg gtaatcgaga
    53101 aatcttgata ttcttgtttg cttgatttga tctcattcac caagcgtttt gtttcttttt
    53161 cgattccatt caagaaggtt cctgcttgtt tctttcctgc agcaatagct tcaaggtctt
    53221 tttcccagct ttctgtcaaa tctggtgtta ctaaagaggg atttaccaat actaataatt
    53281 gcttaccttt aggagatact tgcagtcctt gaggggtacg ttccatcagt tcagatttga
    53341 ttagtttctc gataatctct gcacgcgtag ctggggttcc cagactgtat ttttccattt
    53401 gaccaagcaa gcttgcttct gacaatggtt taggcggtgc agatagttct tttttgatgg
    53461 tgaaatcggg attgattctc atttcttttt cccatttgac tgtttccgtc tcagtttcag
    53521 tttcgccttt ccatcctgct tggacgacac gattttgccg aaaaatgaat cgttctttac
    53581 caaattcaac cgtaactttt gtttggctga ctttatgggg ttgagcaaac agtcctaaaa
    53641 aacgagagac aatcatttga tagatttttt gctcttcatt acttaatttt tcataacgtg
    53701 ctctgttttc agttggcaaa agtgcatggt gatcggtcac tttactgtct tggaatactt
    53761 ttgtctgttg gacgatggct ccgtttttca aatactgctt gacctcagga gcaaagtcgc
    53821 tgactgcttg caatcgttct ttcatcgtac ttttcatgtc atttgtcaga tatttgctgt
    53881 ctgtacgcgg ataagtaacg atcttatggg tctcatacaa actttgtaca agacttaatg
    53941 ttttctttgc agaatagcca tagcgttgat tggcttctct ttggatctct gttaaatcat
    54001 aaggcaatgg cgcagattcc gtttttaatt tttcttggac ttctgtgaca gttcctttgc
    54061 ttgtactgat caattgaaca agtttttgtg cttcttcttg tgtttttaaa gcaaattgat
    54121 ttttttgaag cattttggct tgttcttttc cagcttgcaa cgtgatcgtg aaatacgttt
    54181 gtggacggaa ctgctcgatt ttcttttctt ggtctctcac taatgctagt gtcggtgtct
    54241 gcacacggcc tgctgataaa ttatccgcgt acttcacagt taaggctctg gtcacattca
    54301 atcctaccag ccagtccgct tttgcccggg caagagcaga ttcatacaat gcatcatatt
    54361 ctttcgcagg tcttagttgc ttgaatccag ttttgattgc tttatctgtt tgagaagaga
    54421 tccataaccg cttcactggt ttattgaaat gcacatactc taagatccag cgagcaacaa
    54481 gttccccttc tcttccggca tctgtcgcaa tgactgcttc tgagacatct tttcgctgag
    54541 ccagctgctt gattgctttt aattgatgtc ctgttttagg aagtggtttg attcctagtt
    54601 ttttagggat cattggcaac gtgtccattt gccagctctg ccattcctta ttcagatctt
    54661 ccggcatttt caatcctaat aaatgaccaa gggcccaagt aacgatcacc ttgggtcctt
    54721 cataataatt tttgtgcttt tgattagcac caagcacctt gcttaggtct ttcgcaacgc
    54781 ttggtttttc cgctagaatt agttgtttca taaaattcct ttccgctttc tactgtgatg
    54841 ggctgatgat ttttcaacaa cgcaagtcct ttgtattgct gtaaatcatc gtcacactct
    54901 tcacaccagc gctcatctcc gtcattccaa aaggcgctga gaaagttact ttttgcattg
    54961 atatattcat aattttgatg gatttcgttc cattgttttt cgtacgcttg tcgtgcttct
    55021 tcgaaagact cgaatgtttc ttctgcttca atatcttctt cccagtcttc aaaaaaccac
    55081 caaggctcat tgtccccgaa catggtaatt acttgataca tactcgtgct ccttctttca
    55141 gcttttctag acttatctta gtcacttttc aagaaagttg caagaattat ctcttataaa
    55201 aggatcattt aatgaacatc ttgaaaatga tataaatgaa tctgattgtt taaggcaaag
    55261 tagcgataaa gtcattgatc atccaaaaat agctgtcctc tggatcgatt gtcgattctt
    55321 ttgtaaagta tcctaaaaaa cgcaaggaaa gatagccgtg gatcatacta cataattctc
    55381 tgcttcggtg gactttttct tctttcgtta attgaaaagc ctcaaagatc tgcaaaatga
    55441 tctggttcgt ttcatggatt ccctctaata aaactgcttc attggtgtgg ggcacactga
    55501 tcagtaactc atacactgct tgatttgaaa aagcaaagga tcgataagtt tctgcataga
    55561 tctgcagtgc ttcctgacca ctttttccca caagagcccg acgcagctgg tcattaagtt
    55621 cctgcagaag tttcgctgtt agcgctgttt tgacatcacg aatatttttg aaatggttat
    55681 acagcgaggg agccttgata tccaagcgtt ttgctaaatg ctgaaaggtt atttgctgaa
    55741 catccatctc ttctgctagt tctcgaaagc agtcgatgat tttctcttga gacagatttc
    55801 tttttttcat tttcatgttt cctctcataa aataaatcct tcactctttc agtttaccac
    55861 gaaaaagaaa gagaaaaaag agactttcat tgataaacta catattgtag tttataacaa
    55921 aaagctgtag atgaaaattt tcagaaagaa ggagtctaat tggctgcaag aataaaggaa
    55981 aaattattta ggaaaagaga aacttgggaa caaaacttgt ttgtcttatg gtttggaaca
    56041 tttatggctg gtatcggatt tagtttagtc atgcctttta tgtcacttta catagatacg
    56101 ttaggtaatt atagtacgtc acaattgaac ttttggagcg gattgacttt ttcatctact
    56161 ttcttggtga ctacgctgat ctctccttgg tggggaaaat tagcccacca aaaaggaaga
    56221 aaattgatgc tgttgcgtgc ttcattagga atggcaatcg tcatttcttt gatgggttgc
    56281 gtgactagtg tgtatcaatt agtcgcattg cgtctgcttc aagggatttt ttctggttat
    56341 atcagtaatg ccgctgccct tgtcgcaact gggacgccaa aagaaaaaag tggtcaagtt
    56401 cttggaactt tagcaactgg ttctgttaca ggaacattac ttggaccgct tcttggcggg
    56461 atctctgctt cagcgtttgg ctatcgccct acctttttca ttacagggat catcttattt
    56521 ttcgtcttct tgttgagtct gtttttcgtc catgaaaaat ttgtcccagt gaaaaaagaa
    56581 aacatggttt ctgccaaaca gattttcaaa gacttgaaat atccacacgt cgtcatcggt
    56641 atgttcgtca caacgatgat catccaagca tccaacaatt ccattagtcc aatcatcagt
    56701 ctgtacattc gccaattgct gcatggacat gggaatgtta cgttgatcag cggaatcatc
    56761 gcttcgatac ctgggattgc cactttgata gccgctccaa gatttggtcg cttaggtgac
    56821 aagattggga gtgaaagaat acttgcgatt ggtttgggtt ttgcgattct ggtttatatc
    56881 ccaatggcat tcgtcacgaa tgtttggcaa ttagctgcct tacgtttttt gatgggtatc
    56941 tctgatgctt gtctgctccc tgctgtccaa gcattgatca caaaatattc tcctcatcaa
    57001 gctgctggac ggatcttcag ttataaccaa tctttccaag caactggtaa cgtagtagga
    57061 cctatgatcg gctccagtgt ttctagtgca tttggttatc gtggcgtctt tctttcgact
    57121 tctcttcttg ttttggtcaa cttcttgctt gtacgacaca atacacaaga gatccatcag
    57181 caagaaactg cagaagaaaa agcttcagga gtctccatat cttcagggca ctctccttct
    57241 catagacaat aagcgtaaat gaaaaacact gcttgaacag ttgtcacaga ctgtccttgc
    57301 agtgtttttg tttaggcctg ttttttcaag aactcagata agaggaataa tcccttttcc
    57361 aaggtttctt ttttacaaca gtaacctagt cgggcatgct tcggtaaatc aaaggcactt
    57421 cctggtacta atagtactcc tgtttcttct aataaattga tacaaaatgt ctggtcatct
    57481 tcttcgatgg ctaatttaat gaaagaagta gagacgtaat tgggagcgac aagttcaact
    57541 ttcggttcat tggctaccca ttgttttaaa atcacaaggt tctctgtaat gatctttttg
    57601 tttcgctcca atattttttc tttattcttc aatgcatgta cagcaagatc atctgacagg
    57661 actccgccgc aaatcatcgt gtagtctcga tactttcgaa aaacttctgc caactcaggt
    57721 ccagtagctg tccagccaat acgaatacct ggaatggagt aggttttgga tagggaattg
    57781 gttgctatac ctttttcata gacatctacg atcgacaaga attcaccttt atccgttaaa
    57841 ggcgcatata cttcatctat caatacatat gcatctactg tacgagcaat ttctgcgatt
    57901 ttttctaaag ttttccgatc tagcaatgtg cctgtaggat tgtttgcact attcaaacag
    57961 atgatttttg tttcaggttt gactaaggct tctagctgtt ctaaatcaaa ctgccaatct
    58021 tcttcttcct tcaaatgaac aaagtcaaca gcggcaccta aagatttggg gatgtcatat
    58081 aattgctgat aagtaggaag catcgaaaca acatggtctc ctgcttccac taacgcgtat
    58141 agagctaaaa gattagcacc agtcgctcca ttcgtttgta agatgttttc cggatcgacg
    58201 gtttgataaa gagaagcgac ttcttgtttg aaaacatctg atccttcgat ccagccatag
    58261 tccaatggtt cgtttttgcg tttttcgaaa aattcactta cgctagtccc atctaagcca
    58321 acgagttcgt ctaatgtcaa tgcttcgatc gagctttgtg caatatcata taccgctttc
    58381 ttttcccatt tatttagcca ttcttctaca ccgaaatttg cgattttcat gtttctttcc
    58441 cccttatatc ttgatccagc ctacagcaag caacccgatt gaaagcagtg cggccacaca
    58501 aatcagccca atcattactt tttcttttcc cgtaatttga tgtttggttt cacgacaagc
    58561 gatccagtag aagcaaaaac caggaagata ggcaatacta cataaaagga cataagaaaa
    58621 tcctgctaaa atgatgccca tcaattcaaa agctacagca atcccaccga tcactacttg
    58681 ttttttgatt ccttctttta aagaaaactg gacttgatag atcccgacaa gtagataaca
    58741 aatcaaaatt gccgctgtac ataaagaata ggcaaattga taggcataat cagtaactaa
    58801 gaaagtcaat aagaatagat tagtcaagat tgcagtaaca actaacgaat aagttggggc
    58861 atttttttta ttcgtttttc cccaaccttt cggcaacaga ccgtctcgag ccatcaacat
    58921 cgttgtttct gctgggagca tcgtccaaga caaccaagaa ccaatgatcg aaataatcaa
    58981 gccgatattg atcagcgctg ctccccaatt tcccacgatt ccttttaaaa tatttgccat
    59041 agcaggttgt gaaatagttg ctaactcttc ttgagataag acgccgtatg gcaagatcga
    59101 agcaaggata tagataaaca ataaacaaag cagaccaatg atcgatgctt gctgggcttc
    59161 tgaacgtttc ttcgcgcggt tggctaaaac acttgcgcct tcgatcccta caaagaccca
    59221 catcataacc atcaaacaac ctttaatctg caaccagatc gttccttgct gccctgttcc
    59281 attcactaga ttatcagata cgttacccca aaaatcagca gtgaatatat tcactttaaa
    59341 tgcgataaat acaaatatta aaaataggaa taatggcact aatttacaga tcgtcacgat
    59401 tgtattgatg acgctcgctc cttcaactcc attgtttact aataaagtca gaccccaaat
    59461 aaaaatactt gcaaataaaa tagaaggaac attttgtcca cctttgaata tcgcgaaaaa
    59521 ttctcccatg gcgctcatca gcatcgttgc aaaagcaaca tttcccagcc acgcagacaa
    59581 ccagtaaccc caaccactga tgaagccacc taatttacca aatgaagctt ccgcgtaacc
    59641 gaaaatacca ccatctagat ctggacgttt ttctcctaaa tgattcagcg ataataccaa
    59701 agctaaaata ccaatcccaa cgattatcca tgaaaggatc gctggccctg gagctgcaga
    59761 actagccaga tcacttgtga tcccaaacac accgcttccg attgacgaac tgacaaccag
    59821 agcaaccagt ccccatttgc taatacccgt tgatttcttt tccatttcca tcaccctcac
    59881 ttataaaatt gaacaaatca cttgcaaaag atttccttct attttgcaac tgctcttgct
    59941 taacaaaaag caactttatt catattattg gatattatga actttttaca caagtatttc
    60001 aagtataaaa tgaataaaaa ttaattttat tgcaaaaaaa cagctatgct atccaaaaga
    60061 aaaggtgttt cttttgttag ccatagctgt tttgattcat ttaatatcgc ttaaacgtat
    60121 tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac caccacccag acattccatt
    60181 tcatcataaa atacaactgc ttgtccagga gtgattgcac gtacaggttc gtcgaatacg
    60241 acttctgcat gattatcatc caataagcga actgtcacag gaacgtcttg ctgacgataa
    60301 cggaatttcg ctgtacactt gaattctttt ggcattggtt cattcgtcgt aaagtggatt
    60361 tcacttgcat ccaagcttgt ggcatacaat gcaggatgat ggaacccttg ccccacatat
    60421 aatgtgtttg tcgctagatc ttttcctaca acaaaccagg gttcttgcga atctcctccg
    60481 ccaccgatcc ctagtccttg acgttgacca atcgtataat acatcaagcc agcatgttgc
    60541 cctttgactt caccatcaag agtgaccata tttccttttt ttgctggcag atagttgctc
    60601 aaaaattgtt tgaagttctt ttcaccaata aaacagattc ccgttgaatc ttttttctta
    60661 gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt ctgatttttc catgccgcct
    60721 agagggaaca tcgtttttga aagctgttct tgtgataatt ggctaaggaa gtaagtttga
    60781 tctttattat tgtctactcc acgaagcatg tggaccacgc cgttttcatc gcgagtgact
    60841 tgcgcataat gtccagtagc tacataatcg gcgccaagat ccattgcata atccaagaat
    60901 gctttgaatt tgatttcttt gttgcacatc acgtctgggt taggtgtacg tcctgcgcgg
    60961 tattcggcta ggaaatattc aaatacacga tcccaatatt ctttttcaaa attcacagaa
    61021 taataaggaa tcccgatttg agcagctact ttcgctacat ccttataatc ttccgtggcc
    61081 gtgcatacac cgttttcgtc cgtgtcatcc caatttttca tgaatattcc gatcacgtcg
    61141 tatccttgtt cctttaacaa aagtgctgtt acagatgagt cgacaccgcc gctcatccct
    61201 acgacaacgc gtgttttgct gttgtctgtc atgatatcac catcatttca attagattct
    61261 gaaacatcta cgagttgaag gtcgcaactt ttcagtattt tacattatac gtcatatttc
    61321 tgaaaatttc atcccttaat tatcaagtcg taaaaatact gttctactgg acctattcag
    61381 tacacaaaca tgatagtcaa tcaaaaaatc actcatcttt tgagcattcg atataaaaaa
    61441 ttggcatact cataaaaagg gccagccttt cggcaataag gaataatttt ataaattgtg
    61501 aaaaactatt tttcaaaatt gcttcttatc gcttaaagct acacgtctca tttacaacct
    61561 tttcttttta gatgttatga gttgctcaga taagtgattt tgtttactct aagaaaaaag
    61621 ggaggcaaaa gatacatgaa ttactttacc agtgatatgc actttttcca tgaacgctta
    61681 ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg tggatgaaat gaaccaacag
    61741 ttgatcacta gctggaatgc agtaataaaa gaaaccgacc atgtttatca tctaggcgac
    61801 cttgctatgc atccgcaata tgaaaaagca aatgcagaaa ttttggaact ggtcactcaa
    61861 ctgcaaggaa caatccactt gatcaaaggg aaccatgaca gtcgcgcttt tttccgttat
    61921 ttagaaaaaa atgatcctag gcttactgac ggaagtccca aattttattt ttatgatgta
    61981 ggtgccatcg ttaaattcga ccatcaacaa tattacttga ctcattatcc gatgttgctc
    62041 gggcctaacg acactatccg caatcttcat ggacatatcc atcattacag cgtacctatc
    62101 gagaacgatg tcaatgtagg cgtagacgca ccggaaaggg aactcttaaa ggaaaaacta
    62161 ccatttggca ctccgttatc tgagcaacaa atcaaagaaa tctatgaagc aaagaggaag
    62221 tacgataggt cgtgaaaaaa ctgccctata tcaagtatta aacaaataaa gataattact
    62281 catatttttc atttgagtag gcttattgcc acaggaacat taggatcaga aatggagttg
    62341 taacaagact tctgtcacaa ctccattcca tactattcgt ctttttactc atggtgttct
    62401 tttaccaatt ttttctgtaa ttctttatca taatttcgag cagctgacgt taaaaataaa
    62461 acgattccgc ataataaaat cccgattcca gaaaacaaga acattttttc tacccctaaa
    62521 cgatcagcta atggtcctgc aaataataat ccaattggac ctgccaggtt catcaaagag
    62581 ttgaagttcc ctaagacacg acctaaaaca ttcgattcat aactctgctg gatcattgcc
    62641 atcagcagtg tattgaaata tggcgttgca caacctgctc ctgcattcaa gataagaaag
    62701 tacaagaacc cttgactatc gtttggaacc aatccgcttg caccgatcgt caggcccata
    62761 atgatgtagg ctataataat aggtttcatt cggtctttcc atgttcctat aaaactgatc
    62821 agtgcaccgc ctaagagcat tccgactgcg tagactactt ccactgctcc cgcctgtcca
    62881 acggaaccac caaagtaatc tagcgtcatc aatggataca gactgattgc tggcatgaac
    62941 aacagcatca caaatgcacc attgatcgtt atgtaccata accctttgtt atccatcaat
    63001 tgctgcagcc caaattttgc atctttaaaa atagtaagcg gaacttccaa tatttcagga
    63061 gaaacttttg ggatcttcac aaaaatcaat aagccgacac caaaaactgc ccccaataca
    63121 tctaataaaa taaggtaatt gacaggaacg actgaaaaca aagccgcacc tagagctggc
    63181 gcaatgatga aattcgctga ttggaccatt cctaactgtc cattcgtcct tgttatgtga
    63241 gaagatggaa cgattgtcgg cataatcgac tgatcgttgg catttggaat gtttgtgcga
    63301 ccgaacgcat aaacaaagac acaaaaacta gccaaatcgg gaaggattct gaaatcgttc
    63361 cgactactgc taaaataagc gcgaaaatcg ctacaataat atccgtgaca atcaaaagag
    63421 cttttttatc ccagcgatcc actagcggtt ctacaaatgg gcttagtaaa accatgggaa
    63481 tcattcctag taaagtagca aaactcaaaa ttgtcgccga accggtttct cttgtcaaat
    63541 accagatgat cgcatattgg acgaccatac tagtgattcc tgacaaaaac tgtcccgata
    63601 aaaagaacaa ataatttctc ttccaattcg ttaaaacgac cgactgttca ttttccataa
    63661 acatccctct tttctttttc attttgtata gcgtttgcac aacaatcatt atacgggatt
    63721 cttttttcaa aaaatacctt tttccctaaa taacaatcgt ttcaatttaa atttctttac
    63781 ttagaaacaa taaatcagca aaatattaaa aataacaaca tgtgttaaat ttaaaaataa
    63841 aaaagacaac taatttgcgt cgtccttaca aagttagtca tctaacaata ggccgtttca
    63901 aaactagttg tctttttata tccacagatc attcgacttt ttcgaataac ccacggctaa
    63961 tcatcccatc catcagaaaa taaaatttat cttggctcat tttctgtttt ggatctttga
    64021 aaatattgac tgctttcaat ccatttgctg tagtgatcga cattttcaat gtttgaatat
    64081 cttttgatac agtgattttt aatttgaatc cttctttgct ttgcggcgtg gcatctaatg
    64141 gtcggatcaa ttgataattg cctccgtttg tttctgtaaa tccattatcg cgcaatgtat
    64201 atctttttgc atcaggatgc aaacgatagc taattggtgc gcccagtacc gttgctgttg
    64261 tttcaaatgc catgattttc acctcgataa aattagtttc tctttattat aaaagtttat
    64321 cctgattttt actaggtttt tcagttaagt tccctaaaaa atgaaggcgt tctctcagac
    64381 atctgttcat ataagaatga cttcactagt tattttttga cagcacgaac taattgttca
    64441 aggaaatact ggatgtcgtc ttcggtattt cccaaaccaa agctgatacg gatggattct
    64501 tttagtatcg gtgtatcttc tccatacatt gcttctaata cgtgtgaagg ctcgatatta
    64561 cctgctgtac aagctgaacc agtagaaata gcgaccccat taagatcaag cttcatcagt
    64621 agcaaatcat ttgcttcgcc aattaagcga agattcaaca catgagggag tttattcgtt
    64681 aaatcaccat ttacttgata agggatttcg tttgcttcta atgtatcaag aatcaattgc
    64741 tggaatcctt tatatttgtt gttacgtgct tcacgttctt caggtgacag cagttcaact
    64801 gcttttgcca taccccagat ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc
    64861 tgctccccgc ctaaaagcaa tgcagggata tttactccgt ctcgtttata taagaaaccg
    64921 acgccttttg gcccattgat tttatgagca gagatactta ataaatcgat tcctaattct
    64981 tctggatgga tcgtttggtt tccgtacgct tgtaccgcat ctgtatggaa ataagctgga
    65041 tgatccgcta aaagttcacc gatttctttg attggcatca aatttccgat ctcattgttc
    65101 ccatacatca cagagaccaa gatcgtatct tctcgtaacg cttttttgac ctcttcgatc
    65161 gacagattcc ctttttcatc tacaggcaga tatgtaacgt caaacccctt tgtctctaaa
    65221 tatttcatgg tattaagaac agcaggatgt tcgatagctg tagtgattag atgtctgcct
    65281 tctttttgac acgagaacgc tgtttctaag atagctgtat tatccccttc tgttccccca
    65341 ctgttaaaga tgatctcgtg aggttttgct tgcagactgt ctgcaatgat ttgtcttgct
    65401 gtttccaatt tttcatgcgc gtggcgacca aatccatgta tgcttgaagg atttccaaac
    65461 gtgtcttgca tgattgccgt catcgcttca attacttgtg gatgcatggg ggtagttgcc
    65521 gcatgatcca gataaatagt tttcacttca ttcatccctt ccaaattatt gctaggcaca
    65581 ttctagcata aaatagcgaa caaaccaaag aagagctcat ttttgtctag aggacgtttc
    65641 atgggcatag aaaaaaggag ctatgacaaa agtcttgtcg cagctccttg aagctgctca
    65701 cttgtgtcac aacttctttc cctctttttt ttgtttattc gaattctttt tcttccagac
    65761 ggaataacgg actcatcggt gtattttcat ggatgcgttt gaccgcttct cccattaatt
    65821 ctgaacatgt aacgattgtt aagttttctg gatgacgatt ttcttctgtg aaaacagaat
    65881 cagtgataca aatatctttg attggtgcat tgtctaaaat acttttcgca tgatcggaca
    65941 ataatccatg tgacgcacag gcatatactt cttttgcgcc gttttctttt aatacatttg
    66001 ctgctcgtgc aagcgttgct cctgtgttca agatatcatc taccatgata catgtctttc
    66061 cttgaacatc accgatcaca taaccaccct cagttgaagc atcatctgca tgatctacga
    66121 tggctaatgt gctgttcaaa tattctgaaa gactacgtgc acgctgaaca ccgctgtttt
    66181 ttggcgaaac aactacgatg tcatctcccg tcagacctaa ttgacggtaa taatgagcaa
    66241 acaacggcat cgtaaataaa ttatctacag gaatatcaaa gaatccttgt acttgaaccg
    66301 tgtgcagatc taaagtcagt actcgagttg cccctgcttc ttcgatcaag ttagcgatca
    66361 atttcgcagt gatcggttca tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt
    66421 aaggcaatac gacattgatc gttttcgcac ttgctcgctt cattgcatcg atcatgatca
    66481 gtagttccat atagtagtca ttgacaggtg cattcgttga ttgaacgata tacacatgat
    66541 cccctcgaat actttcttcg atattgatgg aaatctcgcc atcactaaat tgcttcacga
    66601 cgcttttacc taattctgtt ccgaacactt tcgcgatttt ttcagctaat ggacggttgc
    66661 cattcaaact aaaaatcttc aacgtgtcat cctgatactt attactcatg tagtcctccc
    66721 caaaacttct ctattcttcg atagtttaac atatttttcc aagattttct gttaatttca
    66781 gcaaattctt aaggaagtga aactgttccg ttactccaac tggcaggaat gactttatga
    66841 taatcgcccc agttgtcgtg tactttgtaa taacgttctc ctgtttcagt ttcaaaataa
    66901 gcgtacgctg tcacccaatg attgccatat gtactgccaa gtactttcaa aataccaatc
    66961 atcacaggtt tgccttcacg tatacgtttt gtagctcgct gccatgaacc tagaagagtt
    67021 gctcgtgcac gctcatgatt gccattcttc tttaaaaaac tagaaatccc tgtactaacc
    67081 tgaaaaggaa tcgtaggaag tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa
    67141 accaacgaat cagccgtatt tttcttgcga atctcatttg gaagcatcca ctccttacga
    67201 tagtcttgat aataggcaag gagaactgct gccgcgtaag taccacaaag atagcctgag
    67261 ggggtagccc atttcttata cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt
    67321 gcgagttcct ttcctgacct tttttcttcg atcaaagcgg gaatatcttc ttttctgttg
    67381 atccatctag ataactcgat tggctcttca ttgatcagct tccatttttt acaagaaaga
    67441 ccctcttgat aagtatattt tgctggagaa tattctaccg gatgtcctga ttgatcgata
    67501 atcacataac tttgatcttc aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac
    67561 tgcagctgct gagtgctggc taatttttta atttttttat ctactttgaa atataaaggt
    67621 ttatccacta cttgattcag ttgggatcgc ctcctttttt tcattataag tgaaggattg
    67681 aaaaaaacaa atcagtttga ttgttcgaat tttcaatttt ttatgttcta tttgttaatt
    67741 ccttcatttt gtaagataat gggcacacga aacaaaaaag gagcgatcga tgaatgaaca
    67801 aagaacgatt gaaacaagat ttctatgaag cagtcaatga agaatggcaa aaaacagcaa
    67861 aaatccctgc agataaacca gctacaggcg gtttccaaga tttagttgac gggatcgacc
    67921 aacttttgat gggagaaaca gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa
    67981 aaatgaaaca tttccttgca tattatcaac tggcaaacga ttatgaccga agaaatgagt
    68041 tgcatgctca accacttcaa cctataatcg aaaaagttga atcattgcag tctttcgacg
    68101 aattgaatga gcaatttcca gaatggctgt tggatacatt accattgcca tttaatctgg
    68161 atgtagatgc agatatgaag aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt
    68221 tattccttcc agataagacg tattatgcat cagaccatcc caacggtgca caactaatag
    68281 gcgttttctt tgatatggct gttcagttat tagagcttgc cggcaaagaa aaaagtcagg
    68341 cagaagcaat cacggaacaa gcagtgcaat ttgataaatt gattgctcct catgtaaaaa
    68401 gtgcagaaga aaacgcagat tacagcaaaa tgtataatcc gcaatctttt gatacattta
    68461 ttcaatacac agataaactg gacttgaaaa aacttgtcac gggtttgatt gggacaactc
    68521 cagataaagt gatcgtaact gatccagtgt acttcgatca tttgaatgac atcctgacag
    68581 aagctcattt tccgttattc aaaagctgga tgatcattaa aacagtacgt tctcttagtg
    68641 gttatctatc agaagaattc cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa
    68701 cagacgaagc aatgcctcag aaaaaagcag cgtattacct tgcctctgga caattcgatc
    68761 aagtagttgg cgattactac ggaaaaaaat attttggcga agctgctaaa aaagacgtag
    68821 aacaaatggt gaaaaaaatg atcgccgttt ataaaaaacg tctagaagaa aatgactggc
    68881 ttggggatgc aacaaaagaa aaagccgtca taaaattaaa taacttaggt atccaagtag
    68941 gctaccccga taagatccca gcattattcg accagttcaa aacagtacct gcagatcagg
    69001 gtggtacttt gctttcaaat actcttgttt tcagcaaact cacattaaaa gatcgtttca
    69061 gcaaatggaa caaaccagtg gatcgttcag aatgggaaat gagtgctgac acggtcaatg
    69121 cttattatca tccatttcgg aatgtgatcg tctttccggc agcgatcctt caagcaccat
    69181 tttacagtct agaacaatca agctctgcta attatggtgg aatcggagct gttatcgctc
    69241 atgagatttc ccatgcattt gataataacg gcgctttatt tgacgaatat ggcaacttga
    69301 acaactggtg gacagaagaa gatcttacac aatttcaaaa caaagcacaa gcaatgatcg
    69361 aagaattcga tggtctgcct tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg
    69421 aaaatattgc tgatgcaggc ggtctaagct gtgcattgga agcagcaaaa acggaatcag
    69481 atctttctat cgaggaattc tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa
    69541 aagaatacca acaactttta ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa
    69601 acgtgcaacc aaaaaacctt gacgaattct atgaaacatt tggtatcacg gaacaagacg
    69661 ctatgtatct agcgccagaa aaaagagtgc gaatctggta agaggttgtg ccagaagtgg
    69721 tcagcttcaa gaaataagaa ggaattgggg aaaattgctt ctcaaatttt tgtgacattt
    69781 cggcttattt ttcgaagaag ttacttctgg aataccatgt atcagaggtt gtgaaaaagc
    69841 cgcttagttt caagtagtaa gaaaaatttt gtgaaaatag ctttccacat ttttgcataa
    69901 atttgactta ctactgagaa actggctttt gaacaccgtt tatcgagagg ttgtgaaatc
    69961 agcgtcctga cctgagtatt agagaaaaaa cggaaaaata gttcctcata ttttgccgtt
    70021 tgttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag gttgtgaaaa
    70081 agctgtcctg catcaagtaa taagaacagc caatcaaaag cagcaaggag aacctcatct
    70141 ataaaaagat agaaggaagt gagacatcta ttggtctcat ttccttctat ttttactttc
    70201 ctcagtcaat tgttttacat cataaaagga gaaattccac ttattttttt cgctgtttca
    70261 tgacataaac aactacaccg attaacaaaa ttcctccagc taatgctagc aacgggttat
    70321 taaattctcc cgtttttggg agtccttgag tgccattttt ttcactttct tttgctgtcc
    70381 tgtccggatg agaaggtttt ccatttggtg attcatttgg tgattcattt ggtgattcat
    70441 ttggtgattc atttggtgat tcatttcctg gattttctct ttctggtttg tcatttcccg
    70501 ggggcacatc ggcagtttct cgcacagtga tcgctttttg ctgggtaaca gattctgtat
    70561 gagcagacca tttttcccca tcaaatattt ccgaacgata agtgacttct agcgtatatt
    70621 ctccttttga aggtgctgaa aaaatagcgg tatgattaga aaattgagca cttgactgtg
    70681 tttcaacgat ttggatcttt tctgggaaat aacgcatatc ttcaaagaca ggcgttcctt
    70741 gatttggtgt gaaagttgac acaaaaactg taaaaggctt cagttcaatg atatttcctt
    70801 ctgcattctc cgccacacca tttgcttctt gtataataat cggattattt tgttcatttg
    70861 gttttgtctg atttggttct tgtacgattg catactctgg atattccgaa gatggcgagg
    70921 tttctccgtc aaaaatagca cctacagata atggaagacc atccactctt tccttttctg
    70981 tttgacgatt ccccggttta atctgcatca gtccatgaac atggatactt ccattttcat
    71041 agcgcgtaac aggctgctga ccttctttcg aacatgtatt tagagactcg atccaatctt
    71101 ttgatacggt atgtccaaga gtattttctg attgtttctc tcgttcattc caatagtagt
    71161 tcaacgagtg gtagatttga tcttcgtttt gattcaatgg gcggatctgc tctctcatct
    71221 caagattctc tgttcggaaa gataagatac cagaagcatg gtagtctgtg tttcctgctg
    71281 aagaggtata aagagccaca ttatatgaac cgttattaaa acttgtactg ctattgacga
    71341 taatatctgt tccgctattg gaatcgattc ctttcgcaag attttcgaaa gacaaactat
    71401 tgatcaattc atgagggccc gttaaaaaag aaccgcccat tttgaatcca ttaccgttac
    71461 cttctccctc aattcccggt acccagccgt ttcgataagc aactgagttt ttgatgatta
    71521 cttttccgat cgaacctgtt tcatttttag caaaaaggtc ccaaccgtca tctgcattat
    71581 gatacgcgat acaaccgtca aatacatttc cttctcctat tgtcagtttg gccgcaaatc
    71641 catcggcatc ttcaaatcct ggatcggcat tttcaaaaga tgtacagttc ttgactaagt
    71701 tatgcgcggg ccatgcttcg aaaggatcat ttgagctacc gctgatttgg attcctgtat
    71761 ttccattccg ataagcatga atctcttcga tcaaattatg atttccagaa atctgtaatc
    71821 ctttttgcat agctgcacta tttgtaatgt caaaccctcg taaaccccag tagtgactga
    71881 acagtgtcat cccatttcca gttcctttaa aatcaagtac aggacgcttg ttttctggat
    71941 ttttctctgc aatcaactta atcgggtttt ctcttgtccc gttaacgcct ttgggaatcg
    72001 tcaatcctct ttcgaaggaa taagttccag gcgccatgac gattgtctgc ccagcatatg
    72061 cgtatctcaa tgcttgtgtc agagataatg gattttgtct gcttccgttt cctgcatctg
    72121 acccttctgg tgttacataa actgtcgaat atttaggttt acggtagtcc actgtatgaa
    72181 gaatctcttt tgtttcataa ctagtcatct ctacgtattc ttctggcgga tagtttttat
    72241 ctggcgtaaa actgaaagta aattcgttcg ttccttccat cagttttgtc tgataatcaa
    72301 attcccgatt cgcagtgata gccaagtctt ttgcgttctt aagcacctct cctgttgctt
    72361 tatttttaat tgtcaataat ccgtcagcat ttgctctaaa ggacatagta tgatcttggt
    72421 ttcctgaatg attactagag gtcacagtgt aaatcggatc aatcaagcga gtaggtcttt
    72481 cttgcccagg aggatctgtc gcaggatctg agtaagcaac ttcgattcct tctaccttga
    72541 tcgtcatatt ccttgctgca gcaaatcctg cataaataac cgattcatct gaagcgtata
    72601 atttttccca gtcatacatg atgtcagaag ccatttcttc tcctgtttca ggatcgtaat
    72661 aatatgcctc taaaccagta ttcgtttttt tcatctctac gtccagttta gtaatcgagt
    72721 tcgtggccgg aaacagattc ccatgaccgt ttccgaatat attataagaa cctgtttctt
    72781 tttccaagaa ccctgctgaa gtctctaaag gtgttgtttc cactgagaca ctcccaggag
    72841 ctggcgcagc ttgcggatct tcagatgata ttcctgtgat tgcccgtgtc cccaatccaa
    72901 gtcgcatcgt atatttgctg ccgctcgtgt tgaccacttc ttgtctatcc gagtcccaga
    72961 catattcgat ccgactgcct agtatggcaa atgaatttga ataaaatgcc tgcccaaaca
    73021 aatgatcttt tggtactgcg tctcttacca ttaaagcaaa tccttcttgg gcattcgtat
    73081 aggtgcaaga ttctatttcg atcgtcgccc gcatcctaaa gttgatgtct ttggggattg
    73141 cttgataata ataggtcatt ccatctgatc cgcttgactg gaattttccg ccgttattcg
    73201 tggaagagag ccgcacgccg tcttctaatg gttcaatggc atacctacta gcacttgtgc
    73261 tttctccgaa aacaacccct ttccactctt catttgcttc ttcagattgc ttttttgtct
    73321 tttcattttc tgattctttc atcataggat catttccttc ttccgtatcc atatcttcac
    73381 tagttcttgg tacttcctcc attgttgaca tcccttcaat gttcacgtgt gcattttctt
    73441 cgttcacaga ctgttgttcg ttagcagcaa cttcaacgac agaaattaaa accggggtac
    73501 tgagcataag gagattcatc attagcgcac tgtattttat acgttttttt aacaagtgta
    73561 ttcctcccgc aacaaattag aaaacgttta cttaaagtat tacctaattt atttttactg
    73621 tcaataaaaa acaaaattat aataagtgta ttttataaaa agaaaaaata taacttaagt
    73681 tgttgataac aaagagattt attaacgtaa aaagaataag atttttttaa aataacgtat
    73741 aaagaagagc ataaaacaaa gtcgtttgtt ttatgctctt cttttattat tttgtacttt
    73801 ttattttatc aaatcacttt gtttttttat aaaatttctg cgcctagtgt ggattcaaaa
    73861 tgtctcaatg cccattcatg tccaacggga tcgaaacttg ccacggcatc tttgaaaata
    73921 tggagtttgt atcctagatt atacgcatcg actgctgtat gcaacacaca gatatctgta
    73981 catacgccgg tcaaataaat atctgtgatc tggcgttctc gtaaacggat gtctagatct
    74041 gttccactaa aagcggaata atgccgtttg tctatccaat aaacattttc ctcttgctca
    74101 tagtcttggt ataaactttt taaagagccg tacaattccc gtccacccgt tcctatcaca
    74161 ttatgcggag gaaataagcg gttctccgga tgaaaggaat cttttggatc atgcgcatca
    74221 atggcaaaaa cgacaaaatc cttttgatca ataaacttct ttgtatgagc agtcagcttt
    74281 ttttcaatta cttgtcctgc tgtcccagta gtcagctttc catcctctgc aacaaaatca
    74341 tatgtgtagt caatcgagat caatgcgttc atcttagtcc tccttatacg agatgtttga
    74401 caaattcgat caccatttct gctgatcgtt tgcctgcgtc ttcgataaat tcgtcaaagc
    74461 tttgtgtcgc cgagtgatct gctgtgtcgc tcattgcacg tacgatcaaa aatgggatat
    74521 tgaactgacg agctgtttgt ccaacagcgg ctccttccat ttcgcaagct aatgcttcag
    74581 ggaaattcgt taagatttct ttgattttat ctggcgagtc gacaaatgta tcacctgtaa
    74641 cgatcaatcc ttcttttgcg ttcaaattcg ttgcttttgc tgctttaacc atttcactgc
    74701 gcaaatatgt gcttgcttca taatatagag gcattcctgg taattgtcct ggtttgtagc
    74761 caaatcctgt tgcatctgca tcaaaataag ctactttgtc tgatataacg atgtcaccta
    74821 cttgtaagcc ttcaccgatt ccgccagctg aacctgtatt gatcaccatg ttcacgccgt
    74881 attgttggat caacagactt gtggtaatag atgctaagac ttttcctata ccggaacgta
    74941 cgacgatcac ttcgtggtta cctaatgaac ctgaaataaa taaagcgcct gcgcgttccc
    75001 atgataatgg ttcgcttagg ttctctctca aaatttttac ttcttcttcc attgcgccga
    75061 taataccgat tttcatcttt ttaattcctt ctttctatat aaatgcgatt gctaaaaaaa
    75121 ccacacataa cattaggata acaataataa gagatttcat caaaaaagag ttccatttgg
    75181 tcgtcttttc ccgttcgctg atccttgttt tcgtgattgg tttattcttt ttgctttctt
    75241 tacgataaaa gctggcaatc tttttttctt cttgctgata agctgtttct gcttttcgct
    75301 gtttttttaa tgactcgctt gcttgtgctt gttgtcgctt gcgaagttcg cttcgcgtaa
    75361 taagcggtcc tttggccata agccgatccc tctactttcc tttggtcaat agttcccagt
    75421 attgaatcgc ataaatcgtc tttgcatcac aaatcaactg atctttcatc gcttgttgcg
    75481 cctcttcaag agttagatga tacaactcca gtacttcgtc ttcatcttgt gctaaaggat
    75541 tctcgacctt ctctacccct tgtgcatgat aaatatgaag gacttcatta gcaaaacctg
    75601 gtgaaagata catcgaagta agatggctca gcgacttcgc acgatagcca gtttcttctt
    75661 ctaattctct agctgctgtc atttcgggat tttgtccttc tcctggatcg atttttccag
    75721 ctggaatctc caaaatcact ttttctaaag gttttcgaaa ttgcttgaca agaagcagac
    75781 gatcttgttc gtcaaaagca atgatcccaa caccgccagg atgaaatacc agttctctct
    75841 tcgaagttcc tccatctggc aaacgaactt cgtctacagc aacatcaata atttttccgc
    75901 tatagatttc tttgcgactg attgtttttt cttcaaattg ctcattgttc agcatatctt
    75961 ctcctgcttt ctttgtaatc ataactgctt tttttcattt ttcaattttt ctcaaaaact
    76021 ccttattagt ttaccataga taaaccttag attttctcta aatatagaaa atccttcttt
    76081 agtccgatac tctttctagt agtccgtatg ctaaaataag tatgtaatcg aataacgaaa
    76141 agaattcaat actcaacgat aaatgacatg gagggtttat tatgataaaa cgaaattggc
    76201 cgtggcttct agcattggtc ttgctatttc tctttggttt ttcttttgtt ctaggacttt
    76261 tattgatagg tgtagtttta gttttgtggg gactctttgg ttcgcgcagg aaaaagggaa
    76321 aacaagaaga aattcctgca ctgactaacg aacttgaaac tcactatgaa aaaagcggta
    76381 tgacagcgaa tgaaatttca ttttttcgac aaacaatgaa tcaaacaaaa aatgagatca
    76441 atcaattgca aatgaatatg cagcagacag ccaaacttaa agcaatcgat ctccgccatg
    76501 atccagtcaa agcagcaaaa gctttattca aagaattggt gaaagaacca aaccgactgc
    76561 atgaagcaag tcagtttctt tatacgcatc tgccgaatct agttgatttg acaaataagt
    76621 ataatgagat caatgaccat gagatcaaaa acaaacagac ctatgaaaaa ctagaagaaa
    76681 gcgcgcagat catcgaccag ctgtcagctt taatcgcaca agattatcaa aaattcgttg
    76741 ctgaggatct agatgatatc gacgtagaga tatctgttgc gaaacagagc ttaaagcgtg
    76801 ataataaata tgaaccagaa caaaaggatt aactcttttg ttcataaaag aagactcgga
    76861 acattcagat gatgtctggc tgtttcgagt actttttcta aagtagagac attcatgtaa
    76921 gaatcgagaa cagattcaac aaggaggaat tttttatgga tcataaaccg actgaaacaa
    76981 aagatgttac accagttaac gatacacttg aagatttatt gaacaacccg ttttcaactc
    77041 caacagatac gctgaccact tcacaacaag cggagattga tcagctccaa gagcaacaga
    77101 cagctgctcg tttaattgac aaactaccgg cggaacgcca agaacaagct aaacagctag
    77161 cagcaaaaat cgatgctaat gatgcacagt ctgtcatcag ctacggatcg gctgcccaag
    77221 caaaattaag tgaattctca caatcgatgt tgaatcatgt gcaagcacaa gatattggtc
    77281 ctgtaggaga ttccttaact gaactgatgt atcgtctcca agaagccaat cctgacgaac
    77341 tgcgtgccgg agaagggaac atcttccagc gtgtcttcgg gaaggtcaaa caatcgatct
    77401 atgaagtgac agcaaaatat caaaagattg gtgcacaaat tgacaagatt tcagtgaaat
    77461 tagataaaga aaaagacggt ctgctaaaag ataatctgat gttagaacag ctttaccaga
    77521 aaaacaaaga ctactttgat gcactgaata tttatatcgc tgctggagaa ttgaaaatgg
    77581 aagaacttca aacaacgatc attccagaag cgatgaaaag agcagaagaa actggcgatc
    77641 agatggatgt tcagattgcc aatgattaca cgcaattcct agatcgtctg gataaacgta
    77701 cgcatgatct tcgcttagct agacagatca cgatccagca agcaccacaa atccgtttga
    77761 tccaaaacac aaatcaggcc ttggctgaaa agatccaagc atctatcgct acagccattc
    77821 cgctgtggaa aaaccaagtc gtgatcgcat tgaccttgct tcgtcaaaaa gatgcagtaa
    77881 ctgctcaacg ccaagtctct gaaacaacaa acgacttatt gaagaaaaat tcagaaatgc
    77941 tgaaaatctc agccatcgaa acagcgaaag aaaatgaacg tggaatcgtg gatatcgaga
    78001 cccttcaaac tactcaaaat gatttgatcg aaacaatcca agagacattg cgtatccaaa
    78061 aagaaggaaa agaaaaacgt cgtcatgcag aagtagagct tggacacatg gaagaagatc
    78121 tgaaacaaaa actgttggat ttaacccaat agatcacctt tcgcttgtta ctaaaacaaa
    78181 cgcccaacaa cagtttatta caactgttgt tgggcgtttt tcttatcttt cttctaactt
    78241 ctccattgga gtctatttct cattcatctt gctgtgtcca tagccatagc caaaataaat
    78301 gatcagtcca ataaccatta cgataccgaa cacgatccat gtcacagttt gcagacgaag
    78361 catcaataca atacaagtca agatggaaat gattggcaat agcggaacga atggcacttt
    78421 gaattctcca gcttttggtt tgccaaacat ttttctcaac tttagtaagc ctagactaac
    78481 aagcatcaaa taggcgagcg ccatgatatt cgttagttcc gctaatacat tcaatgggaa
    78541 aaatccggca aagaatacag ctgccacacc agcggcataa gtcgcttttt tcggtgtacg
    78601 atgcttttga tcgatttctg tcataaactt aggaagtaag ccatccttgc tgacagcaaa
    78661 cagtaaacga gcaagtgaat acatcatcga gattgttacc gtcagtagcg ttaaaatggc
    78721 ccctacagcg atcaccgcgc ccactgttcc atgtcctaca tacctcattg caaaagccac
    78781 tgggtcattg actcctagtt cagtatacgg aacgattcct gtcaagatca gcgtcacgat
    78841 gatgtaaagg acagtagcaa tcagtatcga accaatgatt cctcttggca catctttttg
    78901 cgggtttttg acttcctcgg ctgccattgc aacggcatca aatcccaaga aagcaaaaaa
    78961 cacaagagct gcaccatcta gcacaccgga aaaaccaaaa ggcatgaatg gctgccaatt
    79021 atcaggttta acgaaaaata ttcctacaat gataaacaac gcgatgatac caaatttgac
    79081 atataccatg gcattattca aacgtaatgc tttcttggct tcaagcgaca cgatgtaagt
    79141 gacgaatatc actacgagca ccgcaatcaa gtcaatgtat gtaccatttt ccggattgta
    79201 cccgccagtt aatgcttgtg gaagttcggc ccctaaactt ttcaaaaaac cttgcatata
    79261 gccagaccat ccggaagcaa cagaggaaac cgctagtaaa aattccccga tcaacaacca
    79321 ccctgtcagc caggcagcaa attcaccaaa tacaacatac agataggcat atggcccacc
    79381 aatcactggc actcgcgaag caaattctgc gaaacttagt ccagacaaaa tgacaacgat
    79441 tgcagctaag acaaatgaaa atgacagtgc tggaccagca ttttgattgg ccgcaacccc
    79501 tgtcaccaca aatattcccg taccgatgat cgcaccaatt ccaagcatga tcaaatcaga
    79561 cgtttttagt tcttttttca tctcactcgt atgattgaga ttgatctctt tcttacgaaa
    79621 caaatccatt gaagttcctc cccattttag gttggaaaac agcgattaaa ctgttttcat
    79681 ataccctaaa aggataccac ctaaaatgac taaaaggcaa ccaacaataa cataaatgag
    79741 ctcttttttc gtttttcttt cgccaaggat gaaaatccca cctaaagtag agataatgat
    79801 ccccatttgt gaaagtgaga agccaacagc taaaccaagt gatttgactg ttagaagcat
    79861 gcagatgttt cctaagcccc ataataatcc acagatcatg tttttccaca caaactgatc
    79921 gactttaact ttacggaaag caaagaagct tgcgcctaag atcattccga tactttgagg
    79981 taagataatt gacatcgcat ccaaattcgc ccagttgacg atgatggtat atacaccata
    80041 accaatcgta gagaagatca atgctctaaa acccttacca aaatcaagca ttttattatc
    80101 tgtatctatt tttccttcgt catcttgtcg ggcagtcaaa tacgcaccgc ttacaagaag
    80161 agctaaagca ataataccgt atacataatc tttcgtttgt gtccattcat ggaagaaaac
    80221 ggctcccgca atcgtattca aaattaattg aaaaccagta gacaatggta accctacaga
    80281 aacacccatg tacttcattc catggaactg tccattttgt ccaacactcc aagctaagcc
    80341 ggataaaaat ccgatcaaga aaatccaagg ggtgattaca ggactaacaa cgaaaaagac
    80401 aactaaagaa aacagaaatg caccgatcgt cattcctagt gtttgttgat tggcatcgcc
    80461 accaatttta ccacttacta aaccaatact accccatgcc aacataggga ctaatgctat
    80521 taaaatttcc ataaccaatc tccttttatt tcacatgata agaaacttat cagcgaaaac
    80581 gttaacaaca caagcacttt ttttcgtttc taacgatttt ctaacgtttt tcattataaa
    80641 aatttaagat tgggaaaaat aaagtcattg ttgtcccttt tccttcagtt gattcagccg
    80701 tcaaatggat acctaatttt tcggccagat tttttgctaa ataaagtcct aatcctgttg
    80761 aatgtgtttt gctaagtcga ccatttctcc cagtaaatcc cttatcaaag atccgtttca
    80821 agtcttccgc tgggataccg atccctgaat ctttaactga aaggctgact ccttgtgctt
    80881 ccttttctat gctcacaatg atgtttccgt gatccggcgt atatttgatg gcattactaa
    80941 gcaattggtt gaagataaaa gcgatccatt tagcatcggt caaaacagta tgatcctcac
    81001 caacaatctc gtagcgaata tttttttgga taaaataatt tgcctgactg cgtatcacag
    81061 gctgaatgat tccttttagc ctatattctt ggatgaggta gtcccgcgaa aaactgtcta
    81121 gtcttgcata atacaaaact tgttctacgt attcatcgat ttttgataat tcattttcta
    81181 gtaatgtata cttttgatcg tcaatatcga actcgatcga acgaactagc aatttagaag
    81241 cggaaagtgg cactttgatt tcatggaccc atgagtcaat ataatctttt tggtcttgtt
    81301 gattactgat tgctgattgc attacttctt ggtgttcacg gatcagctga ttgatatatt
    81361 cttctaccag tttttcttct tctgttcgtc caccgctcaa atagttttgc aaaggggaag
    81421 ttttttgtat gtcggctaat tttccccacc atcttctctt gctcaagtaa ccacccagca
    81481 gataaaaaat cagaaagacg ccctcaatca aagctaaata agcaattgtg ctcaaatcaa
    81541 ctttgatgtt tggcgccagc cacatcacaa agatcgtcaa tgcaataaaa aacagccatc
    81601 ccaagatcaa tgtccactga tctttcaaat atttaaaaaa attcatctta accgctcatc
    81661 ctttcaggga acgatatatc cctgtcctac ttttgtttcg atatatcctt ggatacctgc
    81721 ctgttcgatt tttcggcgta accgattgat gttgactgtc aatgtattgt catctacaaa
    81781 tcgttcgtca tcccacagtg ctcgcagcaa tttttcccga cttaagatct ttccattgtg
    81841 cttcatcaaa ataaataata gacgatattc atttttgctc aaatcaatga tctctccgtt
    81901 gatttccata cttccgttgt caacattcaa cgtaatgcca ttgtggctca tcatttcact
    81961 agataattct gtgtagttgt aagaacggcg aagtaatgca ttgatttttg caatcagtac
    82021 atcgatttgg aaaggttttg tcacaaaatc atctgccccc atgttcatag ccatgatcat
    82081 atccatattc gtattcctgc tggagataaa aatgatcggt actttcgata cttcacgtat
    82141 tttttgacac caataatagc catccaaaac gggaagatta atatctagta atacaagctg
    82201 tggttcttct ctttcaaagt ctgagaacac ttgattgaaa tcggtcgttc caaaggtttc
    82261 aaattgccat ttctcaagtt cctccatgat caattgtcga atgatctctt cgtcttcgac
    82321 taccatgatt tttgccataa aaaatccctc catctttctt cttgctacta caatatcaaa
    82381 gaagcccttg tgaaacaagt tggcttacct ggaaaatgtc attttagcaa acgttaaaaa
    82441 aaactggaaa tatgcgattt aatcgctttt gtcttttcaa tacagcttaa atttattatg
    82501 ttattcttaa caattggtct atgatctgtt atttttcctt agttgttttt gtcttttaaa
    82561 tttccaataa caccaataac cgaaaagcgt tagcactagc aatataccta gaaggagtat
    82621 aagtaatcga taaagatggt atttttttgt ctgttctatc tttgaagaga cttcttctgt
    82681 aaagggaact cgccttcctg tcactagtaa tcggtgagtg ttcacggtgt aaggtgtaca
    82741 agtgataagt gtgactagat cctgcttttc tctgattgct aatgtatttg tttttgttgg
    82801 aaggacaaca attttctcaa cgacttcata agcgagcatc cgaccataca cttcaagata
    82861 gaatcggtca tcttgctcca tttcttcaag atccgtaaag agttttttct cagcaatacc
    82921 gctatgggcg gtaatcacgg aatgtgtact ctctcctcca gttggaaaag aggtgccttg
    82981 caggactgtc gctcctctat ctaacaaaag atcattcgtt tcatcaaata aaggcaagct
    83041 aacattgatt ttcggaatat agattgctcc gatcatatgt tgttcgtagt attcttttcc
    83101 tggatttcgg acatttctaa ccgcttgctc aaaaggatct ttgacttgtc ccattcctgg
    83161 gattactgat gtatgagcaa gcgtctgatt tttcttttca tgcactgcta attgttgctc
    83221 atgtttttct tctttatcgc gttcaagctg cttttgataa ttctcgatcc ttctttgatc
    83281 caaataattg ctgagagcat ctgctaaaaa tggatatgta aaaactgcag ctccggcaag
    83341 aaacatcact gccataaata attgtaataa aagactgatt tgggtttgag gtctattacc
    83401 tgttctcttt ttcattttct tcaccttctt atttaaaaaa actgcagcaa tcggttttat
    83461 aaaggttgct gcagcttatt tttgttgctt atacttcaga cttcatttta aatttacggt
    83521 accagctgta cgctccaatc atcaaactta ttccgattag taagaatgcc aagagcccgt
    83581 tcccaccagt agcaggaagt gacccgcgtt tcatattcgg tactctttct ggccctggat
    83641 tttctactcc tacgatctga atttcttcat tatagcttcc ataagagatg ataaattcag
    83701 taaaggctgc ctcacctgtt ggaagtacat a
//
LOCUS       DAPBBR010000004        78462 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPBBR010000004 DAPBBR010000000
VERSION     DAPBBR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 78462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.004"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1818
                     /gene="acm"
                     /locus_tag="RD488_000255"
     CDS             <1..1818
                     /gene="acm"
                     /locus_tag="RD488_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HDT7656358.1"
                     /translation="ENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2090..2575)
                     /locus_tag="RD488_000256"
     CDS             complement(2090..2575)
                     /locus_tag="RD488_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDT7656359.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    2665..3010
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3055..3696
                     /locus_tag="RD488_000257"
     CDS             3055..3696
                     /locus_tag="RD488_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7656360.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            3715..4350
                     /locus_tag="RD488_000258"
     CDS             3715..4350
                     /locus_tag="RD488_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7656361.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4368..5183
                     /locus_tag="RD488_000259"
     CDS             4368..5183
                     /locus_tag="RD488_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7656362.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5502..6938
                     /locus_tag="RD488_000260"
     CDS             5502..6938
                     /locus_tag="RD488_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7656363.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7127..9574
                     /locus_tag="RD488_000261"
     CDS             7127..9574
                     /locus_tag="RD488_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7656364.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            9804..10871
                     /gene="rlmN"
                     /locus_tag="RD488_000262"
     CDS             9804..10871
                     /gene="rlmN"
                     /locus_tag="RD488_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7656365.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11064..12167)
                     /locus_tag="RD488_000263"
     CDS             complement(11064..12167)
                     /locus_tag="RD488_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7656366.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            12720..13268
                     /gene="aac(6')"
                     /locus_tag="RD488_000264"
     CDS             12720..13268
                     /gene="aac(6')"
                     /locus_tag="RD488_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7656367.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            13814..15475
                     /locus_tag="RD488_000265"
     CDS             13814..15475
                     /locus_tag="RD488_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7656368.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPIPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15545..15892)
                     /locus_tag="RD488_000266"
     CDS             complement(15545..15892)
                     /locus_tag="RD488_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDT7656369.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            15976..16917
                     /locus_tag="RD488_000267"
     CDS             15976..16917
                     /locus_tag="RD488_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656370.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            16918..17961
                     /locus_tag="RD488_000268"
     CDS             16918..17961
                     /locus_tag="RD488_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656371.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            17967..19037
                     /locus_tag="RD488_000269"
     CDS             17967..19037
                     /locus_tag="RD488_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656372.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19027..19980
                     /locus_tag="RD488_000270"
     CDS             19027..19980
                     /locus_tag="RD488_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656373.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            19992..21002
                     /locus_tag="RD488_000271"
     CDS             19992..21002
                     /locus_tag="RD488_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7656374.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21287..22108)
                     /locus_tag="RD488_000272"
     CDS             complement(21287..22108)
                     /locus_tag="RD488_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7656375.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22205..22483)
                     /locus_tag="RD488_000273"
     CDS             complement(22205..22483)
                     /locus_tag="RD488_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656376.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            22751..24760
                     /gene="metG"
                     /locus_tag="RD488_000274"
     CDS             22751..24760
                     /gene="metG"
                     /locus_tag="RD488_000274"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDT7656377.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25239..25826)
                     /locus_tag="RD488_000275"
     CDS             complement(25239..25826)
                     /locus_tag="RD488_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656378.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26001..27323
                     /locus_tag="RD488_000276"
     CDS             26001..27323
                     /locus_tag="RD488_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7656379.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27478..28254
                     /locus_tag="RD488_000277"
     CDS             27478..28254
                     /locus_tag="RD488_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7656380.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28247..28816
                     /gene="rnmV"
                     /locus_tag="RD488_000278"
     CDS             28247..28816
                     /gene="rnmV"
                     /locus_tag="RD488_000278"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDT7656381.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            28809..29693
                     /gene="rsmA"
                     /locus_tag="RD488_000279"
     CDS             28809..29693
                     /gene="rsmA"
                     /locus_tag="RD488_000279"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDT7656382.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30144..30773
                     /locus_tag="RD488_000280"
     CDS             30144..30773
                     /locus_tag="RD488_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656383.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(30896..32005)
                     /gene="ugpC"
                     /locus_tag="RD488_000281"
     CDS             complement(30896..32005)
                     /gene="ugpC"
                     /locus_tag="RD488_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDT7656384.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32214..32636
                     /gene="mgsA"
                     /locus_tag="RD488_000282"
     CDS             32214..32636
                     /gene="mgsA"
                     /locus_tag="RD488_000282"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDT7656385.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            32959..33495
                     /locus_tag="RD488_000283"
     CDS             32959..33495
                     /locus_tag="RD488_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7656386.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(33535..35298)
                     /locus_tag="RD488_000284"
     CDS             complement(33535..35298)
                     /locus_tag="RD488_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656387.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35301..37016)
                     /locus_tag="RD488_000285"
     CDS             complement(35301..37016)
                     /locus_tag="RD488_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656388.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(37795..38019)
                     /locus_tag="RD488_000286"
     CDS             complement(37795..38019)
                     /locus_tag="RD488_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656389.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38210..40987
                     /locus_tag="RD488_000287"
     CDS             38210..40987
                     /locus_tag="RD488_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7656390.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            41068..41487
                     /locus_tag="RD488_000288"
     CDS             41068..41487
                     /locus_tag="RD488_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDT7656391.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            41499..41969
                     /locus_tag="RD488_000289"
     CDS             41499..41969
                     /locus_tag="RD488_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7656392.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            41986..42765
                     /locus_tag="RD488_000290"
     CDS             41986..42765
                     /locus_tag="RD488_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7656393.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            42752..43573
                     /locus_tag="RD488_000291"
     CDS             42752..43573
                     /locus_tag="RD488_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7656394.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            43590..44639
                     /locus_tag="RD488_000292"
     CDS             43590..44639
                     /locus_tag="RD488_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7656395.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            44652..45656
                     /locus_tag="RD488_000293"
     CDS             44652..45656
                     /locus_tag="RD488_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7656396.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            46289..47308
                     /locus_tag="RD488_000294"
     CDS             46289..47308
                     /locus_tag="RD488_000294"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7656397.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            47351..48232
                     /gene="galU"
                     /locus_tag="RD488_000295"
     CDS             47351..48232
                     /gene="galU"
                     /locus_tag="RD488_000295"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7656398.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            48532..48909
                     /locus_tag="RD488_000296"
     CDS             48532..48909
                     /locus_tag="RD488_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656399.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            49515..50129
                     /locus_tag="RD488_000297"
     CDS             49515..50129
                     /locus_tag="RD488_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7656400.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            50902..52641
                     /gene="yfcC"
                     /locus_tag="RD488_000298"
     CDS             50902..52641
                     /gene="yfcC"
                     /locus_tag="RD488_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDT7656401.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            52798..53982
                     /gene="iadA"
                     /locus_tag="RD488_000299"
     CDS             52798..53982
                     /gene="iadA"
                     /locus_tag="RD488_000299"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDT7656402.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            54093..54296
                     /locus_tag="RD488_000300"
     CDS             54093..54296
                     /locus_tag="RD488_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7656403.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(54397..55059)
                     /locus_tag="RD488_000301"
     CDS             complement(54397..55059)
                     /locus_tag="RD488_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656404.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(55072..56574)
                     /locus_tag="RD488_000302"
     CDS             complement(55072..56574)
                     /locus_tag="RD488_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656405.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            57122..58801
                     /locus_tag="RD488_000303"
     CDS             57122..58801
                     /locus_tag="RD488_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7656406.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            58928..59407
                     /locus_tag="RD488_000304"
     CDS             58928..59407
                     /locus_tag="RD488_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HDT7656407.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            59626..60306
                     /locus_tag="RD488_000305"
     CDS             59626..60306
                     /locus_tag="RD488_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDT7656408.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            60314..61645
                     /locus_tag="RD488_000306"
     CDS             60314..61645
                     /locus_tag="RD488_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7656409.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            61660..62622
                     /locus_tag="RD488_000307"
     CDS             61660..62622
                     /locus_tag="RD488_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDT7656410.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            62733..63071
                     /locus_tag="RD488_000308"
     CDS             62733..63071
                     /locus_tag="RD488_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDT7656411.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            63150..63857
                     /locus_tag="RD488_000309"
     CDS             63150..63857
                     /locus_tag="RD488_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDT7656412.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(63960..65441)
                     /locus_tag="RD488_000310"
     CDS             complement(63960..65441)
                     /locus_tag="RD488_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656413.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            65750..66286
                     /locus_tag="RD488_000311"
     CDS             65750..66286
                     /locus_tag="RD488_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7656414.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            66364..67734
                     /locus_tag="RD488_000312"
     CDS             66364..67734
                     /locus_tag="RD488_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDT7656415.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            67801..68136
                     /locus_tag="RD488_000313"
     CDS             67801..68136
                     /locus_tag="RD488_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656416.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(68217..69074)
                     /locus_tag="RD488_000314"
     CDS             complement(68217..69074)
                     /locus_tag="RD488_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656417.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            69181..69696
                     /gene="tadA"
                     /locus_tag="RD488_000315"
     CDS             69181..69696
                     /gene="tadA"
                     /locus_tag="RD488_000315"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDT7656418.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            69719..69803
                     /gene="ffs"
                     /locus_tag="RD488_000316"
     ncRNA           69719..69803
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RD488_000316"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            70013..71398
                     /locus_tag="RD488_000317"
     CDS             70013..71398
                     /locus_tag="RD488_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7656419.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            71435..72112
                     /locus_tag="RD488_000318"
     CDS             71435..72112
                     /locus_tag="RD488_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDT7656420.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            72120..72884
                     /locus_tag="RD488_000319"
     CDS             72120..72884
                     /locus_tag="RD488_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDT7656421.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            72886..73545
                     /locus_tag="RD488_000320"
     CDS             72886..73545
                     /locus_tag="RD488_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDT7656422.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(73575..74084)
                     /locus_tag="RD488_000321"
     CDS             complement(73575..74084)
                     /locus_tag="RD488_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDT7656423.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(74196..75194)
                     /locus_tag="RD488_000322"
     CDS             complement(74196..75194)
                     /locus_tag="RD488_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7656424.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            75395..75979
                     /locus_tag="RD488_000323"
     CDS             75395..75979
                     /locus_tag="RD488_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7656425.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(76056..77249)
                     /locus_tag="RD488_000324"
     CDS             complement(76056..77249)
                     /locus_tag="RD488_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7656426.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            77313..77693
                     /locus_tag="RD488_000325"
     CDS             77313..77693
                     /locus_tag="RD488_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDT7656427.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            77767..78129
                     /locus_tag="RD488_000326"
     CDS             77767..78129
                     /locus_tag="RD488_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656428.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT        25828 a        13447 c        16245 g        22942 t
ORIGIN      
        1 gaaaatatta aaaacctaga ctcagtagaa ggttgggggc aatttgagat acaggccaga
       61 aacgtaaccg ataccggtga agaaaatacg ggaccattca ccgtgacgag cggtgataaa
      121 acagctactg taaatgtgac aaagccagct tctggttctt cttctagcgt tttttattat
      181 aaaacaggag acatgctacc tgaagatact aagcacattc gatggttttt gaatattaac
      241 aataacggca cttatgttga acaaccagtt aaaatcagtg atgaaatcca aagtggacaa
      301 agattagatc caagtacgtt tgaaattaat caaatacact taggtgaaca gaaggtttat
      361 agaggagaag agggaatcca acaattttta caagatttcc ccagcgctac atttaatttt
      421 tcagtaactg ataattacat tgaaataact ataccaaaaa actttgtcaa tcttaggaaa
      481 ataatggtga gttataagac gatcatagaa aacccagaac aaataaattt tgagaatcat
      541 tcggaagctt ggtttaaaga atttaataaa cctgctgttg atggagaaag tttcaatcat
      601 acagttaaaa atatttcagc ttctggtgga gtcaacggta cagttagagg cgaattgaag
      661 attttcaaat atatcaatga cacagagatt ggtatcccaa atgtgacttt cgaattaaga
      721 cgagcagatg aacagcctat tcaaggacag tctagtatcc tgttgacttc gaatgaacag
      781 ggagaagcta gtatcaaagg cctgcaagta ggagactatg ttgtaaaaga aaaagaagca
      841 cccaattgga ttgattttga tccactaagt tcaaatgaac tcaaattctc cataaacgaa
      901 aatgatacag agggagtcag tttacctatt tataacaaga aaaaggttac gaacatcaca
      961 gcaactaaaa tttggaacgg tggaaccact ccaagaccga gtatttattt taaattattc
     1021 agagcaagta caaacaattg ggaaccagtt cctgatgcag aaacaaaacg attagacaat
     1081 ggaataactt cagtgacttg ggaagatatc caacagtatg atgatagtgg aaacgaatat
     1141 acgtttaaag tgcaagaagt agatcaaaac ggaaatgatt atgtcccttc aggttatcaa
     1201 aaaattgaaa acgggctagt cgttacaaat gagaataaag aagtcatttc agtctcagga
     1261 caaaaaacat gggaagacaa tgagaaccaa gacggcaaac gaccgacgac gatcacagta
     1321 aatctattag ccgacggtca accgatccaa cacaaagaag taagtgaaaa agatgattgg
     1381 cgctatcgtt tcacaaatct gccaaaatac agagacgggc aagaaatcat ctatactgta
     1441 acggaagaca acgtgcccga atacagtacg acgattgacg ggtataacat caaaaacagt
     1501 tatacaccgg aaaaaacaaa tatatctata ccaggtagcc atataacacc gtggaaaaat
     1561 tttccagaga agacagagag agagaaaatt agaaatctat tctctcaaaa attgcaaata
     1621 tttgctcata caggagaatc cagcgaacaa agaagcaatt atattagtaa gagagctgta
     1681 cctaaacaga taacaaataa atcaaaaagc attcttccta aaacaagtag taaaaaatct
     1741 agttttgctg taatcattgg tttattgata gtaactatct gtgctgggat attcttacaa
     1801 aaatataaaa aagtttagtt agaatataat attttttgtt aaatatgact gaaatcaaaa
     1861 gaataaaatt ccgatttata atcgaaaaaa gaagcatttt tatatatgct tcttttttcg
     1921 tagaatcaat aaatatggat ttggctaact atggaagaat actcgtatta gttttcagcg
     1981 ttcatactag ttgttacatt gtttgattgg ccaaaagaat ttctgatata ttttgtgcta
     2041 aataaagaaa aagacgcttg aattgggaaa taagaaaact actctatcat tacaaatttt
     2101 cataaactgg cagatgttct aagtaaacaa gtatcttttc aaagtcggaa aaatccataa
     2161 tcaacgtagt ggtattgata tttggatgaa agcctacggt atcttgacga tcaatagcag
     2221 catcgatcac gacttggatt tttttctctt tgtcgtgcat caatgctaat ggagtcactg
     2281 tacctgctgg aacgcctagg aggtcaggaa gctgttcttc agaaacaaaa gataagcgct
     2341 tttcttttaa ttgttcagct agttgtttta aatcggcgtg cttttcatca ggcaagatga
     2401 caagatagat ttgttttcct tttcttgatt tcaataatag attttttact tgcggaccag
     2461 gtagggaaaa agggacattt ttgactgacg taatcgcagg atgatcgact ttttgaaaag
     2521 agatacccag tttttttagt agttcataag cttcttgttc ggttgcacga ctcatcgcgc
     2581 atcaccctcc tttttttatt agtgtatcat aaaaaagagt tgacaaatga aaaataatca
     2641 tgtaaattac acgtaaagtt aaaacaaatg acatcgaaaa gaagagtagc cgttaggtgt
     2701 ttttagagag tctctggttg gtggaaagag gcagcagtta accgtgaaac acatcttgga
     2761 gtcgattttc tgaagcgtat agtaggaaaa tccggggagc ccgttacagc tgcggtcgtt
     2821 gctagatgac cagataaggc tggcttttcc gtgaggagtc ggtaaaaaaa ggtggaacca
     2881 cgtgattaac gtcctttgat cttcggatca aaggactttt tgttttcatc tgaacggcaa
     2941 cgactgtgtg aggttttttc tgcaaggaaa aaataaacag aggtggaacc acgtataata
     3001 cgtcctcttg gcatttgcca agaggatttt tttattttaa aggaggaaaa gaagatggag
     3061 tatttgattg aagttatgcc gcaattatta gtaggagcac tcacaacatt gaaattattt
     3121 ttatttacct tgattggctc attaccatta gggattgttt tagcattagg attgtctttg
     3181 cattttaagc cgctacgcta cttgcttcaa acatatgtat gggttatgcg gggaacaccg
     3241 ctgttgttgc aactgatttt tattttttat gggttgccga cgattgggat cgtttttgat
     3301 cgtttcgaag cagcactcat tgcctttatc ttaaactatg cagcttattt tgcagagatc
     3361 tttcgtggag ggatacaatc gattcctcaa ggtcaatatg aagcagcgca agttttgcaa
     3421 ttaagtccct ttcaaacggt gacgaaaatc gtcatcccac aagtgacaaa gattgtttta
     3481 ccttctgtag ggaatgaagt tatcaacttg gtcaaagatt cttccttgat ctatatatta
     3541 ggtttaggtg acgtaatgcg tgctgggaaa atcgcgatgg aacgcgacgc gactttactg
     3601 cctttgctag gcgtggcaat catctatctt acattgactg gtattctaac aatcgtaatg
     3661 aaacaagttg aaggaaaatt aaattattac cgctaactga taggaggaag aaatatgatt
     3721 gaattgaaga aagtgaacaa agcatttggt gaaaaaaaaa taatcaaaga tttgaatcta
     3781 atcattccag atgggaaaac attagctatc gtaggtcctt ccggtggcgg taaaaccacg
     3841 cttttacgta tcttggctgg cttagaaagt tctgacagcg gagaatttta tttagacggt
     3901 gtaccgttca acccattcga gcttaaaatg aaagaacaag ttgtaggagt cgtattccaa
     3961 gacttccagc tatttccaca tctgaatatt tttgaaaaca ttaccttagc accaaaaatg
     4021 gtattgaaac agacaaaaga agaatacacc aaaaaagcag aagaattagc ggcttcatta
     4081 gggattagtg atttattgaa tatctatcct tatcagcttt ctggcggaca aaaacagcgg
     4141 gtagcgattg ccagagcatt ggctatgaat ccacgggtat tggcttatga tgaaccaaca
     4201 agtgctttag atcctgaatt acgccagcaa gtcgagcgtt tgatcctatc attgaaagaa
     4261 gatggggtaa cccaaattat tgtcacccat gatttagtat ttgcagaaaa tgtcggtgat
     4321 caattactaa aagtttcccc aattcattaa gaaaggagaa gatagagatg aaaaaaacca
     4381 gttttctatt cgctttgatc gcaggtcttc ttctttttgc aggctgttcg aacaaaaaaa
     4441 cttcagcaga taattgggcg actatcaacg aagagaaaaa aatcgttata ggtttagacg
     4501 atacatttgt tcctatggga tttagagata aagacgggaa gctcacagga tttgatattg
     4561 atttagccaa agcagtcttt gaacaatatg ggattacggt agactttcag cccattgact
     4621 ggtcaatgaa ggaatttgaa ctgaacaatg gaacgatcga tttgatatgg aacggctatt
     4681 ccaaaacgcc ggcaagagaa aagaaagtgc aatttacaaa accttatatg gaaaacgatc
     4741 aagtgctgat cacacctaaa gaatcaggaa tcacaaactt tggacaaatg aataataaga
     4801 gattaggtgc gcaaaatggg tcatctggtt atgatgtatt tacgaaacaa ccagaagtat
     4861 taaaagagat agtcaaaaac caagatgctg ttttgtatga tagttttaat gaagcattga
     4921 tcgatctgaa aagcagacgg gtcgatggtc tgctgatgga taaagtatac gcagactatt
     4981 atttgaaaca aagaaacgaa ctagaagact tcaacataac aaaaggttct tatgagagtg
     5041 aggattttgc agttggtgca cgcaagtcag atagtacatt agtgaaaaaa atcaatgaag
     5101 ccctagatca actagagaaa acaggtgaat tccaaaaaat atccgataaa tggtttggcg
     5161 aagatgttac gccgagaaat taacaaatag gggactgtga caaaagacgt gtcacagtcc
     5221 ctttttccga ataaacagtg ttctcctgcc aactccttgt gactcggagc tgaatggcag
     5281 gctcacaacc tcttggtaaa cggtgttcaa aagccagttt ttcggtatta agccaaattt
     5341 atgcaaaaat gtagaaagcc attttcacaa aatttttctt actactcgaa actaagcgac
     5401 tttttcacaa cctcctttac atatttttat tttgttgtgg aaggggtttc gtgttattct
     5461 aaaagaggaa cgattgaagg ttataggaaa ggaagagatg aatggaacac aaagaactta
     5521 cctcatttcc aaaagatttt ctgtggggct ctgcttctgc agcgtatcaa gtagaaggag
     5581 cttggcaaga agatgggaaa ggagaatcag tctgggatcg atttgtacgg atacctggaa
     5641 agacatttaa aggaacgaac ggtgatttgg cagtagacca ctatcatcgt tataaagaag
     5701 atattgcttt aatgaaagaa caaggtctga aagcttaccg cttctctgta gcttggacac
     5761 ggatttttcc taatggacga ggagaagtca atcaagctgg gctcgctttt tatgagagat
     5821 tgatcgacga attgattgaa aacgatattg aacctatgtt gactttatat cattgggatc
     5881 ttccacaagc attgcaagat gaatataatg gttgggaatc acgtcagatc attgaagatt
     5941 tcactcatta tgcagaaaca ttatttgagg cattccgcgg gaaagtccat tactggatta
     6001 gtttgaatga acaaaatatc ttcacttcat taggttattt gttagcagca catccgccag
     6061 gtgtgacaga cccgaaacga atgtatgaag ttaaccatat tgctaattta gcaaatgcat
     6121 ctgtcatcaa taaatttcac gagttagaaa tgcctggaaa aatcggacca agctttgcgt
     6181 atacgccaaa ttatccaatt gacagtaatc ctgaaaatgt tctggctgct gaaaatgcag
     6241 aagacctgat ggccaattat tggatggatg tctatatgtg gggaaaatat ccgattgctg
     6301 ccatgaggtt cttagaagaa aaaggatggg caccaacgat tgaagctggc gatgcagaat
     6361 tgctagaatc tgctaaacca gattttcttg ggatcaatta ctatcaaacg gcgacgaatg
     6421 cattcaatcc attaaacgga gttggtgctg gaaaaatgaa tacgacagga aaaaaaggtt
     6481 catcagaaga aactggagtt cctggaatgt ataaaaaagt tgagaatcca tttgtcgaac
     6541 gaacaaattg ggactgggag attgacccag aaggattaag gatcggactg cgtcgtatca
     6601 caagccgtta ccgcatgccg gtactgatta cggaaaatgg cttaggagag tatgacaagt
     6661 tgacagaaga taaacaaatc catgacgact atcgaatcaa ttacttacaa agccacgtca
     6721 aagccatcaa agaagcaatt tcggatggag cagaagtcct aggctattgc acctggtctt
     6781 atacagattt gcttagctgg ctgaacggtt atcaaaagcg atatggattt gtatatgttg
     6841 atcaagacga aacacaagaa ggatctttgg aacgatataa gaaagacagt tattactggt
     6901 accaaaaact gattgaagaa aatggagaga acctttagtt cacatactta aaacaagaag
     6961 gtacggctgg atatggccgt gccttttctt gataaaatca tttagaaatt aagaaaaact
     7021 gtaaaataag ctgaaaaatg aaagaaagcg tcagttcttt caaacaaaac tttagttccc
     7081 ttactttttt ttgtataatg aaacttgatg aaatgaggga taataaatgg cacaaaagaa
     7141 acggcctact aaaaaaagga aaaagacgaa aaaaacgaaa aagcaaaaac agcagcagga
     7201 acaaatgctg acgattggtg ttgggtttgc cttgatttta tttgctgtct tcggcttttt
     7261 aaaattaggt tttttaggaa tattgattgc aaacggcttt cggatcattg caggaaatac
     7321 ttaccaaatc ctctgtcttt tattagccgt attaggattt tggattgtca ttaagaatac
     7381 agagttttca attggtaaaa accgacgctg gtttggcggc atactctttt atttcggtat
     7441 cttattattg ttacatgccc atttatttgg caaactccat actggggaac caaatatcat
     7501 ggggacgaca tgggatttgt tagccagtga tataaaacaa agtcaagtag acaataacgt
     7561 tggtggtggg atgattggag caatccttta tcattttact tacttcttga ttgcacagcc
     7621 tggaagttat ttagcagcag tgctattact ggcaggagga gcattcctgt tcagtaatct
     7681 ggaaggctat cagctgttaa atggtatcca atcaattgga gaacgagtac aggaattatt
     7741 ggaaggtgat cctgccaagc aagctcgaaa gcaagcggca aaggaagaga gaatgaaaca
     7801 gcgcgcagaa gcgaaagaag caaggcgctt agctgcaaaa gaagctgcag aaaaagaagc
     7861 tgcagaatat gagaagaaaa aagcggtgag ccagcaaagg gaaaatactg ctgatgaatg
     7921 gcaggaacca gaaaatacag agccggagca gctaagtttt gttccaatcg acagttttca
     7981 agaaaatatc catcctgcga atctagagaa accagtacca gatacaccaa aacagaccaa
     8041 tacagcagaa ggtttttcag atgagttgcc agaggatgac ggtacctcat tagaatttga
     8101 gattgaagca gaacaggaaa atcaagacta tgaattaccg acagttgatt tgcttgattc
     8161 tataccaact gtggatcaaa gtgatgagta taaaaaaatt gaaaaaaata tcggcgtatt
     8221 agaacaaact ttccaaagtt tcggtgtcga tgccaaggtc gtcaaagcca gcttaggacc
     8281 atccgtcaca aaattcgaag tccagccggc tgtaggggta aaagtaagta aaattgtgaa
     8341 cttaacagat gatatcgcgc ttgctttagc ggcgaaagat gtccggatgg aagcaccgat
     8401 tccaggtaaa tcactgattg gtattgaagt accaaatgga aagatcagta tggtttcctt
     8461 tagagaaatc atcgaagcac aaccaaacca cccagataaa ttactagaag tacctttagg
     8521 acgtgatgtt tctggacggg tacaaacggc tgatctttcg aagatgcctc acttactcgt
     8581 ggctggttcg actggtagtg ggaagtcagt agcaattaat gggattatca caagtatatt
     8641 aatgcgtgct aagccccatg aagtaaaact gatgatgatc gatccgaaaa tggttgaatt
     8701 gaatatgtac aacggcatac ctcatctgtt gacgccggtc gtgacgaacc ctagaaaagc
     8761 agcgcaagcc ttacaaaaag tagtacaaga aatggaagaa cgatatgaaa aattcgcggc
     8821 aaccggagta agaaatattt ctggttacaa tgaatttgtt caacagaaaa acttggaaaa
     8881 cggaacgaaa catccaacct taccattcat cgtagtgatc gtagatgaat tagctgattt
     8941 gatgatggta gccagcaatg aagttgaaga tgcgattatt cgtttagcgc aaatggctcg
     9001 ggcagcgggg attcatatga tcctagctac tcaacgtcca agtgtggatg ttatcacagg
     9061 aatcatcaaa gcaaatgtac cttccagaat ggcatttgcg gtatcaagcg gtacagattc
     9121 tcggacgatc attgattcta atggggcaga aaagctctta gggcgaggag atatgctatt
     9181 cttgccaatg ggtgagaata aaccgatccg tgtgcaagga gcattcattt ctgaccacga
     9241 agtagaacgg gtcgttcaat ttgttacaga tcagcaagaa gctcattatg aagagaaaat
     9301 gatgccgaca gatgaagttg aaacgacagg tgctccagaa cagccacaag atgagctgtt
     9361 tgaagaagca aaagcacttg tcgttgaaat gcaaacggca agtatttccc ttctccaaag
     9421 aagatttcgg atcggttaca accgagcagc acgtttagta gatgaactgg aagctcatgg
     9481 agttgttggc ccgtcagaag gaagcaagcc tcggaaagta ttcattgagc aggaagaaac
     9541 atcagaaacg ttgccggacg ataatgacat gtaaaacttg tgtgatgaag ggttgaaaaa
     9601 cgaataacca ataaaaagac aaggcatgat gataccaaaa gaaaaaatgg tttttttcca
     9661 tcttttctaa tacggtatga tgtcttgtct ttttagtttt tgtgagatta aagttctatt
     9721 cgatttattt gtgaagtatt gcattaagga aatgaatcat gtatagtatg tagcgaaact
     9781 ttgagaaaaa gagggaaaat actttggaaa aacagtccat ttatggcttg acgaatgaag
     9841 aattaatcaa ttggtttata gaaaacggcg agaaaaaatt ccgagctgcc caagtttggg
     9901 aatggttgta tcaaaaacgt gtaagtaatt tcacagaaat gacgaatcta tcgaaacaat
     9961 tgatcgaaaa attatcggag cattttatca tcaatcctct aaaacagatg gtcgtccaag
    10021 aagcttcgga tggtacagta aaatatttgt ttgaactccc tgataaaaac atgattgaga
    10081 ctgtactgat gagacaagaa tatggcttgt cagtttgtgt gacgacacaa gtaggatgta
    10141 atatcggctg tacgttttgt gcaagcgggc tgctcaaaaa gaaccgtgat ctgactgctg
    10201 gagaaattgt tgcacagatc atgatggtcc aacattattt tgatgagcgc aatcttggcg
    10261 aacgcgtttc acatgtcgtt gtaatgggga tcggtgagcc atttgataat tacgacaatg
    10321 taatggactt tttgcatatc atcaatgatg ccaaaggatt ggcaattggt gctcggcaca
    10381 ttacagtttc cactagtgga ttagcacaca aaatcaagga attcgctaat aacggcttgc
    10441 aagtcaatct ggctatttcc ttgcacgcgc cgaataatga ggtgcgaaca tcgatcatgc
    10501 ggatcaaccg aagtttccca attgagaaat tgatggaagc tgtggatgag tatttagaga
    10561 aaacaaaccg tcgaatcacg tttgaatata tcatgttgaa tcaagtaaat gatagaccag
    10621 agcatgcgca acaattagca gatctattaa aagataagaa aaaattagca tatgtcaact
    10681 tgattccata taatccagtc agtgaacatg atcaatattc tcgcagtcca aaagctgatg
    10741 tattgagatt ttatgatgta ttgaagaaaa acggcgtaaa ctgtgtgata cgtaaagaac
    10801 atggtacaga tattgatgca gcttgcggac aattgcgaag caagcaaatg aaaaaaacag
    10861 ttgccaaata atcgtatcct actcgttttt tcaattacca taaaaggagc agttttctta
    10921 attaaggaac tgttcaactt aaataagaga aaagattcta tagcgaaagc tataaagctt
    10981 tttttgacaa gaaaaaccct catcaagcaa agaaatgtcc tcaatttgat gacagcctgc
    11041 ttgatggggg ttttagcaat tatttaactg attttcttat atccttgctg gctttcttgt
    11101 gtagcatgat aagtttctac gtcaagaatg gcctgtttaa atttttctcg ggtgatttca
    11161 taaggcacat gtttaatatc atttgttgcc atggctttat ctaagattgc ttctaaatcg
    11221 gtcgtgacat tgagattcat gtcggttaac gatactggaa gttggttctt tttcataaac
    11281 acatagattt tatcaaacaa atcgaactgc tgatccatca tcaataaggt cagtacacca
    11341 taactgacag atgctccgtg aaggtatccc tccatttttt ctagaacagt cgtaccgtaa
    11401 tagaatgagt gtgccatagc agaattatag ttattgttaa ctaaaacaga aaccaatccg
    11461 gtagtaacaa tgatatccga aacgacttgt tcaattgcat atgagggacg atcgtcggca
    11521 ctatctttca atgcttgcgt accataagtc aagagacgat caatgcacat ttttccgatt
    11581 tggattccta atctatccgt gtagcctaga tcatcgccac gagcagaaaa agtagattcg
    11641 acttctttgg ataaagcatc gccaatacct gcccataagt atttatcagg tgcttcggca
    11701 ataattgctg tatcaatgaa ggtgtgtaca ggtggttttg aaggaaagaa gagtccgtcc
    11761 attacgcctt cttcgttata gatgacacat accgcagtga cgggcgaaca gttcgaacca
    11821 atagtgggaa aggtgaagac tggtttagct agtttttcac caatgacttt tacagtatcg
    11881 caagcacggc caccaccgac tgcaaacagg acgtctgctt tttggacact ttcatgctgg
    11941 atcaactgtt caatatttcc ataagttgaa ttacccccgt accagagact ggcgacaacc
    12001 tctatttcct gtgtcaaagc tacttttatt ttgttttctg cctttgaaag tgcagtcttc
    12061 cctccaatca gcactacttt tgtcccatat tctttgacga ttccatttgc tttttcatac
    12121 gcatctgttc caatggtata atttggtaag aaaacacttt gactcatatt catttccttc
    12181 tttcttcgtt gaaacgggtt aaaattttaa agagtgatcg atctgactgc ggctgtagat
    12241 ggagtagagg tgaacctaag acaggataag tgatgaataa ggtggcatga acaccttgaa
    12301 atcatcaata agtatcctaa aaacgaacaa gtacaaaaac attgaaaacg acaataatga
    12361 atttttgttc ctcttagtat ttctaccgat tccctttgct tttttgtaat tatctaaaaa
    12421 ttctaaaaat taagattatt atatgaaaac aggttttatt tgtcaattca taattggttt
    12481 tttttaaagc aaaagataat ctatatcatg atgaacaaac agagtttttt cctccaattg
    12541 atggctttcc tgatctttcc tattttgaat aaagtgtttc tgtataattt ttttatttta
    12601 taagtaagat aaataatgaa agaatagaga tactgattgg tagctaaaga tttttgagcg
    12661 agaacatttc gttttttcaa aaggactgtt agaataagca agaacaaggg ggaagacgta
    12721 tgataatcag tgaatttgac cgtaataatc cagtattgaa agatcagctt tctgatttac
    12781 tgagactgac ttggccggaa gaatatggag acagctcggc agaagaagta gaagaaatga
    12841 tgaatccaga acgaatcgcg gtagcagcgg tagaccaaga tgagttagta ggatttattg
    12901 gtgcaatccc tcaatacggt atcacaggtt gggaattgca tccattagtt gtagaaagct
    12961 cccgacgaaa gaaccaaata ggtactcgat tagtcaatta cttagaaaaa gaagtagctt
    13021 ccagaggagg aatcacgatt tatttaggta cggatgattt agaccatgga acaacgttaa
    13081 gtcaaacgga cctgtatgag catacatttg ataaagtggc ttccatccag aaccttcgtg
    13141 aacatccgta tgaattctat gaaaaattag gttataaaat cgtaggtgtc ttaccaaatg
    13201 caaatggctg ggacaaaccg gatatttgga tggcaaaaac gattattcct cgaccaaatt
    13261 ctcaataata aaaagaggtt gtgacagaag taatcagctt caagaaataa gaaggaattt
    13321 acgaaaatta cttcttgaat ttttgtgaaa ttccaactta tttccgaaga agctactttt
    13381 ggaacaccgt gtaccagagg ttgtgaaaaa gtcgcttagt ttcgagtagt aagaaaaatt
    13441 ttgtgaaaat ggctttctac atttttgcat aaatttggct taataccgag aaactggctt
    13501 ttgaacaccg tttattcaga taagggactg tgacaagact tttgtcacag tttctttttg
    13561 tttattcttt tttatctttg tatggcaata atagacaata taacgaaaat tatttaatgg
    13621 cttttggaag accatggaaa accttgtaca aagctatttt ttctgaaaaa ttccttgaaa
    13681 cctcacgaaa aaatcattat tttatgaaaa agacaaaaaa aagtgttgat tttttaataa
    13741 ttattcatta aactcttaaa caacttcaga aaatattaat tattctgaaa attccaataa
    13801 aggggtacgt aaaatgaaaa agaaatttac atttggtttg gttgcggtat gcggccttgt
    13861 acttgctgga tgttatggcg gcagttcagc cacaagcagt agttcagcaa aaagcggttc
    13921 agcagatgga ggaggcgtat ttaacttagt cgtgcctcaa gaaatgccta cagctgactt
    13981 atcagttgca acagatacaa tcagttttac agcattgaat aacgtttatg aaggaattta
    14041 ccgtcttgat gaagacagca aaccacagcc ggcaggagct agcgagttgg cagaagtcag
    14101 tgaagacgga ttaacttaca aaatcaaatt acgagaagac gcaaaatggt caaatggtga
    14161 tcctgttaca gcagcggatt acgtttatgg ctggcaacga acagtagacc cagctacagc
    14221 ttctgaatat gcttacctgt atgcgccagt tgaaaatgca gaagacatta cagctggaaa
    14281 gaaagataaa tcagaactag ggatcaaagc agttggtgac tatgaattag aaatcaaatt
    14341 gacgaaacaa acaccatatt tccaatatct gcttgctttc ccatcatttt tcccacaaaa
    14401 acaatccgta gtggaagaaa atggggatgc ctatgcatct gcaagtgata aagctgttta
    14461 taatggacca ttcacattag aagattttga tggaccagga acagatacag aatggactta
    14521 taagaaaaat gatcattact gggacaaaga tacagtaaaa ctttctgaaa tcaaagtcag
    14581 tgtagtaaaa gaatcttcta ctgcattgaa cttattcaaa gatggccaag cagatgacgt
    14641 gatcttgtct ggtgagttag cacagcaaaa cgcaaacgat ccagcttata cttctgttaa
    14701 agaagcgcgg acaagctata tcgaattcaa tcaacgtgaa aagaattcac cattcaacaa
    14761 tgtgaaccta agaaaagcta tttcttattc tatcgatcgt gaagctttag taaaacaagt
    14821 actaggtgac ggatcagttg tctctacagg attgatccca tcagatatgg taaaaagtcc
    14881 aacaacgaac gaagactttg caaaagaagc tggaaaatta gtttcttatg acaaagataa
    14941 agcaaaagaa tattgggaaa aagcgaaaaa agaattgggc gttgattctt tagaatttga
    15001 tttgatggct tctgatgatg attcatcgaa aaaagtaatc gaatatgttc aaaactcaat
    15061 ccaagaaaac ttggatggcg taacagtcaa accaatacct gttccattct ctgtacgtct
    15121 tgaccgctca acttcgggtg attttgacgc agtactaggc ggatgggctg ctgactatgc
    15181 agacccaagc agctttactg atttgtttgt cacaggtaat tcatacaacc gtggtcgctg
    15241 gagcaatgca gaatatgacg aagcagttaa agcagcttca tcaacagacg ctggcgatga
    15301 acaagcccgt tgggatgatt tccaaaaagc aatcaagatc atctctgatg atatgggtgt
    15361 cgttccggtg taccaaaaag cagaaggtca cctagtgaat gaaaaaatca aaggtatcgt
    15421 tcaccatgcg gcaggcgctt catgggatta caaatggaca tacgttgaag aataatcgtt
    15481 aataccgtga gcatgagaaa aaacgaggct gcggcaaatg tcgcaacctc gttctcatat
    15541 tcacttatcc taacaaagaa aaaagcatga aaatagcaga aagagcaatt agtattccgg
    15601 caatgatcag ccaaaagctg tacataccgt agctggcaga cgagagcgag gaaaattctg
    15661 gttttttctt tcggttcctt gttcgtgcaa gatggaccga tcgctgaaaa tgatcgaaga
    15721 aacccgaaga aaagacccat aaaaaaccgc cgataatcag aaacggcaat gaccataaga
    15781 atagatcatt agataattga atgagtgtaa aggaatggtt gatgagattt tttattaaaa
    15841 taaccagaat cagtagaaaa gctactgcgt aggggataga tttttttttc atttgattgc
    15901 tcctttattt ttggttcatt atctaataat gtagcgaaac atctgtcaga agtcaaaagc
    15961 tagggggaaa cattagtgaa tagttatatc aaatatgtat taaaacgtgt ctttttcatg
    16021 atcatcacgc tttggttaat tgcaacaatc acctttttct tgatgcaatt gctgccgggc
    16081 acgccatata cgaatcagga acgtttgagt cctgaaacaa tcgagatgct aaataaacaa
    16141 gtcggtttgg ataaaccagt tatcgtacaa tatgggattt atctttctaa tttgcttcaa
    16201 ggagattttg gaatttcctt ccaatttaaa aaccagccag tcgcacattt gttagctgga
    16261 agaatcggac catccttgca gttagggtta caggcaatta tctttggaac agtcctaggg
    16321 acgattttag gaacgatctc tgccatgaag caaaatacat gggcagatac atcttctaca
    16381 ctcgtagcga tattaggtcg ttccattcca aactttgtat ttgctgtttt attacaatat
    16441 atctttgcaa tcaaattaca agttttgcca atcgcaaaat gggatggctt tgtgtacaca
    16501 atcttaccaa caattgcgtt ggccatgtcg ccgcttgctg actctgctcg gtttatccgt
    16561 acggaaatgg tggaagtact gcatagtgat tatgtggaat tagcaaaagc aaaaggattg
    16621 agccgttggg aaatcgcctt taaacatggt cttcgaaata gtttgattcc attgatgact
    16681 ttattaggac cgttagctgt agcattgatg accggatcac tggtggtaga aaatatcttt
    16741 gctattcctg gtatcgggga acaattcgtt aagtcaatca caacaaatga ttatcctacg
    16801 atcatggctg taacgatcct ttactcattt atgctgattt ttgttatttt gatcgtggat
    16861 ctattgtacg gtctagttga tccaagaatt cgtgtttcag aagggagccg aggataaatg
    16921 gaaatgatac caaagcgtta tgaaacagtt gcagatatcc ctgcggatga atttcttcca
    16981 ttacaaaaaa ataccgaaga agaacgtgaa cagattactg caccttcttt gaattttatc
    17041 caagattcat ggcgccgttt aaagaaaaac aaagctgccg ttatttcaat ggttttacta
    17101 ttggtcatca ttttgatctc tgtgatcaca atctttgttt ctcctcatga tccaactgcc
    17161 caaaacgtgg cttatatcaa tttgcctcct cgtattccgg gaatcaatat cgatggattg
    17221 aatggaaaag caatggttgg tggtgaactt gttgataaat atgctcaagc aaacgtccct
    17281 tcaaacgtaa atttcttttt aggaacagac ggtttgggac gtgatgtatt aagccgctta
    17341 tttatgggaa tgagaatctc gttgctgatc gcatttattg ctgcattact agatgtaacg
    17401 attggtgtag cttacgggtt ggtttctggt ttgttaggcg gacgtgtcga taacgtgatg
    17461 caacgttttt tggaaatctt atcaggaatt ccaaacctcg ttgtcatgat tttgatgttg
    17521 gtcgtttttg aaccaggaat tttttcaatc gtggctgcta tggccatcac aaactggata
    17581 ccaatggcac gtatcgttcg tgcacaaaca atgaaattaa aagatcaaga atatgtttta
    17641 gctggattga cattaggtga atcaagaatg aaaattgcat tcaaacatat tttgccgaat
    17701 atctctagtg tcattattat tcaaatgatg tttagtattc catctgctat tttcttcgaa
    17761 gcctttttaa gctttatcgg tttaggtctt acgcctccgt cagcttcatt aggaacgatg
    17821 ttgagcgaag ggtacaagac attcctgtat ctgccttatc tattatggat tccggcagta
    17881 actttatcgg ttatcatgat tggctttaac ttacttgctg atggattgcg tgatgccttt
    17941 gatcctaaaa tgaaagagtg aagacgatga cgaaaatttt agaagtgaaa gacttagaaa
    18001 tctcttttga tacgtatgct ggaaaggtac gagcgattcg cggtgtcaat tttcatttga
    18061 ataaaggaga aacattggcg atcgttgggg aatctggaag tggaaaatca gtgacgacca
    18121 gaagcatcat gcgcttgctg tcaagcaacg ccaatataga tgctggtcaa atcctcttta
    18181 aaggtaacga tatcgttgga aaatcagaaa gagagatgca aaaaatccgt ggtaaagaaa
    18241 tagcgatgat tttccaagat ccaatgacct ctttagatcc gacgatgccc attgggaagc
    18301 aagtcgctga gtcccttaga aagcataata aagtttcaaa aaaagaggga caaaaagctg
    18361 cattagaatt gcttaaatta gttggaatac ccgaagctga gaaacgtatc aacagttatc
    18421 cgcatcagtt ctcaggaggt cagcgtcaac ggatcgtgat cgcgattgca ctggtatgtt
    18481 atccggaaat cctgattgct gatgaaccta caacagcgct tgatgtgact attcaagcac
    18541 agattttgga gctgctgaaa gaaattcaga caaaaatcga tacatcaatt atctttatca
    18601 ctcatgacct tggtgtagta gcgaatgtcg ctgatcgtgt cgctgtcatg tatggaggaa
    18661 gaatcgttga agttggaaca tcggaagaaa ttttctacaa cccgcaacat ccctatactt
    18721 ggggactgct tggttcaatg ccgacattag atagtgcgaa cgatcgattg tatgctattc
    18781 ctggttctcc accggattta ttgaacccgc caaaaggaga cgcattctat ccaagaaatg
    18841 aattcgcgat gaaaatcgat gcagaacaag aaccaccatt ttttgaacta tcaaaaacac
    18901 acaaggcagc aacttggcta cttgctccgc aggcacccaa agtgacaccg ccagaagaaa
    18961 tccaacgtcg ctgggctatc tttaaagaga aacaaaaaca tacttacggt caaggaggaa
    19021 ttgctgatgc caaataaact acttgaagtt aaaggattga aacagtattt caatgtagga
    19081 aaaaagaatg aagtacatgc tgtaaatgac atcagctttc acatttatga aggagaaaca
    19141 ttcggtttag ttggagaatc tggaagcgga aaatccacta ctggccgtac gatcattcgc
    19201 ttgaatgaac ctactgatgg tgagatatta ttcgacggtc aagatataac gaagatcaaa
    19261 gataaaaaag gtttgacgaa attccggcat gatgttcaga tgatctttca agatccatac
    19321 gcttcgttga atcctcgtat gaaagtcaga gatatcattg ccgaaggaat tgatgttaat
    19381 ggactagcta aatcatctga agagcgtgca aaaaaagtcg atgatctatt gagaactgtt
    19441 ggattgaatc caagccacgg tactcgttat cctcatgaat tttcaggtgg gcaacgccag
    19501 cgtattggta ttgcacgagc attggcagta aaaccgcgtt ttatcatttg tgatgaacca
    19561 atttctgcac tagatgtgtc gatccaagcc caagtggtca atttgttgca agatctccaa
    19621 aaagaacatc aattgaccta tctatttatt gcacatgatt tgtcgatggt taaacatatt
    19681 agtgaccgaa tcggtgtaat gcataacggc ttgttattag agatgggaac aagtgatgaa
    19741 atctataatc acggtgttca tccttataca gaaagtttgt tatctgctat tcctctacca
    19801 gatccagacc atgagagaaa acgcagaaga atcaaatatc aacctgaacc agatgacgga
    19861 caagtacgtc aacttcgtga aatcgcacca gaacattttg tctatgcaac tgagcaggaa
    19921 gtcccatatt acgcaaaaaa actaaaacga caaaaggaat ctcttctggt tgctaactag
    19981 gagggacata gatgctaaaa gcttttaaat tccgtatgta tccgacagaa gaacaaaaac
    20041 agcaattgat tcgtactttt ggatgtgctc gatttaccta taaccatttg ctgaaaaagc
    20101 ggcagaaaag ttggcaacaa acaggagtag ccaatttttc gctcacaccc gctacattaa
    20161 aaaaagaata cccattctta aaagaagtag acagtcttgc tttagcaaat gcacagctta
    20221 atttggatcg ggcttttcgc aattatttca agggacgtgc cagcttccca aagcttaaaa
    20281 cgaaaaaaag tatgtggcaa tcttatacga ccaacaacca aacccgtacg atctatctgg
    20341 aaaatggcta cttaaagtta ccaaaacaaa aagaactaat caagataaat cagcatcggc
    20401 cagttgaagg atcgattcgc tccgctacga tttctgctcg atataatgaa gaattttatg
    20461 tcgcactact ttgtgatgtt tcgccagtaa aaaaagaatc tttagctaaa tggatcggga
    20521 tcgcctatca tccgaagaca ttgatccaaa catctcgacc tctagaagta actttaccaa
    20581 aatttcacca gacagaagaa aagctgcaac atgcacagcg gaaattgaat gtgaaagtcc
    20641 gctccgctca ccatagaaag atcaggttag atcaggcaag caattatcag aaacaaaaga
    20701 gaaaagtaat ggatctttat ctgaaacaaa agaaccagcg agaagattat cttgaacaat
    20761 tatctgggaa attggtcaaa caatatgact acttatttgt agaatctttt ccaaaagaag
    20821 aggcacatgc tgatttttct attcacgact ggcataaatt aataacaaaa ttgcgttata
    20881 agtcccaatg gtataataaa aaatttcttt tgatcaatac cgacggagca gaagaaagca
    20941 attccgtaag aaagagccaa gtagtagaaa aaatgggcag acattcggtt atcaagggat
    21001 aaaaaatgaa tgaaactgat aggagcgtta gggttagcct tgttaataaa aagtcttaat
    21061 gacttttgtt tctaggaatt tttcttttga agaaaagctc actaattatg acaaaccaat
    21121 aaaacaatag cagaaaaagt tcgtacgagc tttttctgct attgttaatt ttttattcag
    21181 aaagtttacg aatacatcaa aattctgaaa caaaaaacgt aactcacaaa gagttgtttt
    21241 tgcgtttttt cttgaatgat taggtctgaa tcttttgctc acaaccttat tcatggtgcc
    21301 ccggcttgag ctgatagatt tttgaaggac ggccgattcc tacaggacgt tcaccgatct
    21361 catcgaaata ttggagcata gctttcttaa aattggaatg atcgatcgtt ttataatcga
    21421 tccctaagaa tttagcaaat acttttcgag cttccgtaat cgtgaaatct ttacctaaaa
    21481 cttgtagaac ttgcggctcg tgttccattt tattgactac acggttgaat gctttcaaga
    21541 tgatttgact atggtcaaaa gccaaagtat ctttgccaga agactctcca gtgactaaat
    21601 caagcgagat agccacttct ccgctagata aatggatctt gttactatga cgttctagtg
    21661 tgaaccagcg tacttccttg gcatcatctc cggcgattag cggttcttct ccaataaagg
    21721 ctaagtagct gactgtgacg acccagcctc gcggatctcg attaggcgta ctgaatgtat
    21781 gcagttgctc aatattttct tttgaaataa ccacaccagt ttcttccttt gtttctctta
    21841 agacgctttc tccagttgac tcatcctttt ggacaaagcc accaggcaat gcccatgaat
    21901 ttcgataagg atgccctttt ctttggatca acaaaacttt cagctgatct tcttctttgt
    21961 tatagcacat cagtacgata tcgacagtca aagagggctt gtcatattct ggacgttcct
    22021 gtttttgata ccagttaaga aattcttctt cacttgcttt atgttcataa tataattttt
    22081 cttcttcttt agaagcaaaa cggttcatct gaccacctcc attgacagta aaagtacttt
    22141 ttaccttatt gtagcagact ctgaaaaaaa accaaggatt tacttgaaaa atctaggtta
    22201 tcatttaaat atgaaaaata aatggaagta tgagattgaa taaaaagaaa agcagataaa
    22261 acggcaatac tttataccgc tcttcacgaa tggcaaagaa gccacaaata acgatatata
    22321 cgtcaatgat aaaacgcaaa atccaagctg ctgtcataaa actgttcaaa tgcccatgga
    22381 ggttaaaata accatacata cgaatataaa aatagctgaa tattaaatgt gctaatgaaa
    22441 gaaaagcaat actaagtgta aaaaaaagat gtttcttctg catgattgtt ccagtccctt
    22501 actaagatag atagtcttta ttataccacg tgtgagggga gaaataaaaa gccgtttttt
    22561 agtagatatg aaacaaaaca aaaacccgca tttattcaac ctattcatcc ttttaaagga
    22621 tagattgaac gtagatagaa gtcgtttatc cagtcttttt cattttgaaa aaaagctaac
    22681 agcatgcttt ttttatggta tactagcaag gaaacgaatt cgcatcatgc gataaaggag
    22741 gaagagcccc gtggcagaaa aggaaacttt ttatatcact acgccaatct attatccaag
    22801 cggcaaactt catatcggca actcgtatac tacgattgca tgtgacgcaa ttgctcgtta
    22861 taaacggttg atgggctttg atgtgtttta tctcactgga gtggatgaac atggtcaaaa
    22921 aatcgaaaca aaagcagaag aactaggtgt aaaaccgcaa gaatatgtag ataaaatggc
    22981 ggctgatgtc aagaaattat ggaaaacgct tgatatcagt tatgataaat tcattcgcac
    23041 gacagatgat taccataaag cagctgttca aaaaatattt gatcgtttat tagaacaggg
    23101 agatatttac ttaggtgaat atgaaggctg gtactctgtt tctgacgaag aattctttac
    23161 agaaacacaa cttgcagaag tgtacaaaga tgacgaaggt aacgtgatcg gtggtaaagc
    23221 gccaagtgga cacgaagtag aattggtaaa agaagaatca tacttcttcc gcatgagcaa
    23281 atacgcagac cgtctattgg aatactatga agaacatccc gaattcatcc agccagaatc
    23341 tcgtaaaaac gaaatgatca acaactttat caaaccagga ttagaggatc ttgcagtttc
    23401 acgaacaact tttacttggg gagtaccagt caagagtgat ccgaaacatg tggtgtatgt
    23461 atggatcgat gcattatcca attatattac tgcactagga tatggctccg aagatgaaag
    23521 tctattcgaa aaatactggc ctgcagatgt tcagatggtc ggtaaagaaa tcgttcgctt
    23581 tcatacgatc tattggccaa tcatgctgat ggcccttgat ttgcctctac ctaaaaaagt
    23641 atttgggcat ggctggctat tgatgaaaga cggaaaaatg tctaaatcaa aaggaaatgt
    23701 cgtttatcct gaaatgcttg tggaacgtta tggtttagat gcactccgtt attatttgct
    23761 tcgtgctgtt ccgtttgggt cagatggtgt ctttacgcca gaagattttg tttcccgtgt
    23821 caattatgat ctggcaaatg atctagggaa cttattgaat cgaacgattg ctatgatcaa
    23881 caaatattgt gatggactcg ttcctgacta tgcctcactt gtcactccat ttgatagtga
    23941 actgtctacg acggctgcta acgttgtcgg acgttaccat gatgcaatgg aaaaaatgga
    24001 attcaataca gcattggctg aaatctgggt gctgatttct cgtgcaaaca aatacattga
    24061 tgaaacagaa ccatgggtat tagcaaaaga cgaagaaaag aaagctgaat tgaatagtgt
    24121 catgatccat ttagctgaat ctttgcgtat cgcagcgata ttacttcagc caatcatgac
    24181 agaaacgcca gagaagatct tcaatcaact aggattggac tctgaaacaa tgaatcttga
    24241 aggattacac tttggcgaat ttccttcagg aacaaaagta gttgcaaaag gtacaccaat
    24301 cttcccacgt ttagatatgg aagaagaagt tgcttttatt caagaaaaaa tgtctgaagg
    24361 tactcaaaca aacgaagata cagtcaaatg ggatccagaa gaaacagaac ttgtttcaac
    24421 gaaagaaaaa caaatcaaat ttgatgtatt tgaaaaagta gaactaaaag tagcagaagt
    24481 catcaactgt caaaaagtag aaggggcaga taagttgctg caattccgac tagatgctgg
    24541 agacagccaa gaccgtcaaa tcttgtcagg aatcgctgaa ttttatcctg atccaagcga
    24601 attgatcggg aaaaaagtcg tcattgtagc aaatctgaaa ccacgaaaga tgcgtggaca
    24661 aatcagtcaa ggaatgatcc tttctgcaga agcaccagat ggctctttac aagtaatcga
    24721 agcaccaaaa tccatgccaa atggctcaga aatcgcatag aaattcaaag ggggtatgac
    24781 actagttgtg tcataccccc tttttccgaa atttgagaag caattttcgt aaattccttc
    24841 ttattacttg aagccaatca tataatacag aaacagagaa ctatccaaaa taaatcctag
    24901 aaaaagaagt acgagcttcg ctgatttttg ttaatttaga ataatactaa taggaatcgt
    24961 aaaaacagaa aaaaagcata atgataaagg gtcgggcaga ttttaattga ttcatctggt
    25021 actctttttt attgtcctta cattcataaa gtttgaatgc aatgacttta ttacatctat
    25081 atttatatct aacagtagcg ttgatgtgtt aattataagt tctatcactt tatgttcaat
    25141 tagtttgtgc tcttatatgt gtgattgaaa atatagataa aaaaacaatc atcggctttg
    25201 acttcgatga ttgttttctt tattttgtaa aaatcctatc acttgatttt atggtaacct
    25261 tttatttttg tcttcaaacg gcttggtaag agagcagtaa gcagtgcaaa tgggatcgaa
    25321 aagacatacc agaaaatcgt acgtccgata ccataatgtt gatagagctt tgtcaacatc
    25381 acgtgtaaca agatcaaccc taaaagcaag gagccagcta taaaccaatg attatcccaa
    25441 tgcatgactt cactaagtgc catcactcca aaaggataga aataaaaata gatcccgact
    25501 aaggtcatcc gccagttctt tgtaaatgtt ccgatattca ataaaaagaa aatcgctgaa
    25561 agcaaaatac cgataggcgg aaaaagccca accaaaaagg aatacaacat cccccacaag
    25621 atcatcacag gacctttgat caatgcaacg attgcgatga acaaagtcag caatattagt
    25681 ttttgtgata acgttgcaac agtcattaat ccaaataaaa ttaatgtgaa ccaatgccaa
    25741 tgggactgct gttgttcttt acgggaaaaa tcgacccggt tggataaata atctgctaat
    25801 ttcggataag aacgcttaaa atccataaac tgttcctcct tcgtggaaaa ggtaggttta
    25861 gtatacgaaa aataaaaaag aaatacatcc gtcttaagag ggagtttttc actgaaagtg
    25921 gagaaaaaag aatggtaaat taaaatattc tcagttatac tgaaaattat accaaatttc
    25981 aaagaagaaa gaggatggga atgaaaggca aactaaaacg agaaatcaat ctgtttggcg
    26041 cattagctac cgttatggga accgtgatcg gtgcaggcgt cttcttcaaa actgctgctg
    26101 ttactgctag tactcagtct acaagtttga cattgctagc ttggcttttg ggtggtttct
    26161 taacgatctg tgctggattg acagtggctg aattagctac agcaatcccg gaaactggtg
    26221 gagctgtaaa atatattgaa gctgcgtatg gaaaattgcc cagcttttta ttaggatggg
    26281 cgcaaagctt gatttacttt cctgctaata ttgctgcatt atcgattatc tttgcgacac
    26341 aattgacgaa cttattacaa ttatctaccg attatctttt gttgattgca gtgatcaccg
    26401 ctgtttctgt gacagggttg aatttgttag ggacaaaagt cggtgcttct gtacaatcag
    26461 tgacgttgat tgttaaatta ataccaattg ctgtgattgt catatgggga ttattgaccc
    26521 caggacaagg aactgtccag ttatttccaa tcgaagctgg aaaagatgtt acttttgtcg
    26581 aaggattgag cagtgcgttg ttagcaacgt tgtttgctta tgacggctgg ttaggtgtcg
    26641 gtgcaatggc aggggaaatg aaacggccgg aaaaagattt gcctaaagca attattcttg
    26701 gtttgagttt tgtaacagtc gtttatctat tgatcaattt tgtttttttg aaaactttgc
    26761 cgattgatca tcttgccggt aatttgaatg cagcttctga agcatcagac gtcatttttg
    26821 gaggaatcgg tggaaagctg gtcactattg ggatcttgat ctcggtatac ggtgcattga
    26881 acggttatac actaactggg atccgcgtgc cttatgcgat ggctttagaa gacgagctac
    26941 ctttcagtaa acagctgaca aagctttcaa agaagtttac ggttccttat gttcctgcgg
    27001 ttttccagtt agcagtagct tgtattatga tgagccttgg ttctttcgac tttttaacag
    27061 acatgttgat ttttgtgatg tggctattca gtttactgat ttttatcggt gtctttattt
    27121 taagaaaaaa agcgccggaa ttgccacgtc catataaagt accactttat ccaatcgttc
    27181 cgattattgc gattctcggt gctattttca ttttaggtat gacgatgatg acgcaaacga
    27241 aattagcatt gatcggtata ggtgttacct tgataggtat cccagtctat tatcaaaaaa
    27301 agaaaaaacg ctcagaagag taaaatattt caacaacaga cagaaaaagt acgaactagg
    27361 tcctctagat cttcgtgctt tttctatttc aataaaacaa gttcttctat tttgattttt
    27421 gctacttctg caagtagtgc ttatgtgcta aagtaagaat gaaaaggaga gataaacatg
    27481 atatttgatt ctcataccca tttaaatgct gaacagttca atgaagatat tccagaaacg
    27541 attcagcgag cacaagaaat gggggtaacg aaaatggcgg tcgtgggctt cgatacgcca
    27601 acgattgaaa agtctttgca attaagccat gactatccaa atatatacag tattatcggc
    27661 tggcatccga cagaggctgg cagttatacg aaagaaatcg aaaataaatt acaagaacaa
    27721 ttgactttac caaaggttgt agcattaggg gaaattggct tggattatca ttggatggaa
    27781 gacccgaaag aagtccaaga taaagtattt cgcagacaga ttgctatcgc aaaagaaatg
    27841 aacctaccaa tcagtattca tactagagaa gcacttgaag acacgtatca aatcctaaaa
    27901 gaagaagatg ttcgagatat cggtggaatc atgcatagtt tcagtggtga ttatgaatgg
    27961 gcaaaacgat ttcttgactt agggatgcat atttcattta gcggtgtcgt cactttcaaa
    28021 aaagcattag acgtccaaga ggctgcagca aatgtaccaa tcgaacgatt acttgtggaa
    28081 acagatgccc cttatctggc accagttcct tttagaggaa agcgaaatga accaggctat
    28141 actcgttata cagtagaaaa gattgctgaa cttcggaatc ttccgacaga agaagtggct
    28201 gcccaaacat ggacaaatgc gcaccgatta tttggtctaa gcgaacatgg ataagatgaa
    28261 gatccaagag attatagtcg ttgaaggaaa agacgataca agaaggctgc gggaagtagt
    28321 tgatgcagat acgatagaaa caatagggtc tgcaatcaat gaagagatcc tgatgcaaat
    28381 tgaacatgcc caagagactc gtggagtgat cgtttttacc gatcctgatt tttcaggaga
    28441 aaaaataaga aaaatcatta tggaagctgt tcctcaggca aaacatgctt ttttgccgcg
    28501 cacacaagct aaaccaaaga aaaagggaag ccttggtgtc gagcatgcaa gtgatgctgc
    28561 tattttagaa gcattgaaaa aggtcgtgac gccagacatt tcccaaacgg ctgtttctga
    28621 aatcactaga caagaccttt tagactatgg tttaatagct ggggcacaag caaaagaaaa
    28681 acgagaaaaa ctaggtgacg agttgcgcat cggttacacg aacggcaaac aattggaaaa
    28741 acgtttgaag atgtttcgta ttacgccgaa agaactcgcc caagcaatga aaatagtgga
    28801 ggaacaacat gagtgaatat cgtgaaattg cgacaccctc tagaacaaaa gagattttat
    28861 tgaaacatgg tttttcattt aaaaaaagtt taggacaaaa ttttctgact gaaccaaata
    28921 ttttaaggaa aatcgtagaa actgcgcaaa tagatgaaca tacgaacgtg atcgaagttg
    28981 gaccaggaat cggtgcattg acggaacaat tagccaagca tgcaaaacaa gtcgtagcat
    29041 ttgagatcga tgatcgtttg atccctgtat tggctgatac gatgcaaccc tatgacaatg
    29101 tgactattgt acatcaagat attttaaaga ccgatttgtc aacagctgtt agagaaacat
    29161 ttcatgagga gcttccgtta aaagtcgtag cgaatttacc ttactatatt acgacaccga
    29221 tcatgatgca ttttcttgaa tcagatttgg ttgtggatga actagtcgtc atgatgcaaa
    29281 aagaagtagc tgatcgtatc tctgctgaac caggaacgaa agcttatggt tcattatcga
    29341 ttgctgttca atattatatg gaagccagtt tagcattcat cgtaccaaaa acagtatttg
    29401 tccctcagcc aaatgtagat tcagcgattt tgaaactgac aagaagagat ataccggcag
    29461 tcgaagtgac agacgaaaaa gcatttttcc gattgacaaa agcggcattt cagcaaagaa
    29521 gaaaaacgct ttggaataac ttgcagcatt cgtatggcaa agatgaccag acaaaagcat
    29581 ggttagcaaa aagcttggaa acagctggaa tcgatccaaa acgtcgtggg gagactttgt
    29641 cattacaaga attcgccgca ttaagcaatg cgatgtcaga aaatatgcag taaaaaaaga
    29701 ggttgtgaca gaagttgtga aaaagctgtc ctgcatcaag taataagaac agccaaacaa
    29761 aaatagttcc tcatgttttt cgtttgtttg ggcttattac cgcagatgca agcttttgaa
    29821 caccgtttaa gaaagaggtt gtgggcctgc cgtttaactc taagtcacaa ggaacaattt
    29881 caaaaaacag cttctcatgt ttttgagtta gttggtctta ttacttgatg caagcttttg
    29941 accactatta tgccgaacaa ggagatgtga cacaaatttt gtcacatctc ctatttttgt
    30001 ttcttgatca aaaaattctt atacttgata ctcacactca ttttgtatgg atttagaaaa
    30061 gaatatgtgt cttgacagtt attagtaagt gagttatact aagtcgacat ttatgtgtca
    30121 agacatatta ggagagagaa aaaatgagaa aaaattcagt tcgaaaacta acgatttctg
    30181 ctttattgat tgggatgggg gtcattatcc caatggtcat gcctaaaatc atgattccac
    30241 cagcttcctt tactttggcg tctcatgtgc cattatttat tgcgatgttt tttacaccag
    30301 gagttgcagt ggctgttgcg ctaggtacga catttggttt ctttttaaca acgccggtta
    30361 tcatcgcatt gcgagcattg tcacatcttg tgtttgcgtt gattggggct tggtacttgc
    30421 aaaagcatcc gagtatcgtt ttaaaaaatg gacagtttac ttttgctaat tggcgtttcc
    30481 aagggttcaa ttttgtgatc ggtgtgattc attctttagc agaaatgcta gtagtcagca
    30541 tcttttactt tattggtaat atgcctgaaa catattattc tcaaggatat ttttatacag
    30601 tattcatctt gatggggatt ggtgggctta tccacagttt agttgattat aatattgctt
    30661 attttatagc aggaacactc agcaaatatt ttgatatccc cgtatttacg gcagcaaaaa
    30721 aagaaaatcg gaaagagtcg attcaagggt acgcgaagaa aacgacatat tagacatgat
    30781 ctctcaaaaa aaaactctca tctagtaatg gataataaat cctctaagat gagagttttt
    30841 tgtcctaaaa agagctgcac caacatcttc tggcacagct ctaacagggg gcaatttatg
    30901 gaagtttgat gacttgttct gtttctttat caaagaagtg gcctttgctg atgttgaagg
    30961 caaggtcgac tatttcgcct ggtttatgga aatctcttgc atctactttt gagatgaact
    31021 cagtagaacc agtttttgtg taaagcatcg tttcagctcc aagtaattcg gaaacgacaa
    31081 cttctgattt cactacggct tcaggtgaag cttcaagggc tacttgttca ctgtggatgt
    31141 cttctggacg aataccgaag ataacttctt ttccttcata acctttttca actaatactt
    31201 tgttttttcc ttcaggaata cgaagcttaa gcccatgtcc atctgtgata acaccatttt
    31261 tcaatgtcac attaaagaag ttcatggcag gagatccaat aaagccggca acgaacatat
    31321 tgacgggtgt atcataaact tctttcggtg taccgatttg ttggataaat ccgtctttca
    31381 tgataacgat tcggtcagcc atagtcattg cttctgtctg atcgtgagta acatagatgg
    31441 tcgttgtttc aagacgctgg tgaagtttgg caatctcagc acgcatggct acacgtaatt
    31501 tagcatctaa atttgataat ggctcatcca ttaagaagac ttttgcatcc cgaacgattg
    31561 cccgtcccaa tgccacacgt tggcgttgtc caccagataa agcagctggt tttcgtttca
    31621 agtattctgt cagacctaag atctctgctg cattgtccac acgttttttg atgtctgctt
    31681 tatcatattt acgtaatttc aagccaaaag ccatattatc aaaaacagtc atatgaggat
    31741 acaatgcgta gttttggaaa accatggcaa tatcacggtc tttaggtgcc acgtcattca
    31801 tgacttttcc gccgatattt agttctcctt cagagatatc ttccagtccc gcgatcattc
    31861 gcaaagtagt tgactttcca caaccggaag gaccaacaaa aacgataaat tcacggtctt
    31921 tgattgatag attaaaatca gttacagaat aattttctgc attgtcatat tttttatata
    31981 cgtttttcag agccatttct accataatac gttccacact ttctttttta gttttattaa
    32041 ctatttaaag tataaatgaa agcgttaact aacttcaatg tcatgttgaa caagaatttt
    32101 ttcttttttt tgtcaatgtg ctagttttaa gctttaataa atatccataa gaaataaaaa
    32161 ctgatacact ggagtaaata agtatgttaa caatatcaaa aggagtgtct cttatgaaaa
    32221 tcgctttgat cgctcatgac cgaaaaaaac ctatgatggt gaaattagca acagcgtata
    32281 aaacaatatt ggaaaaacat gaactttttg ctaccgggac gactgggcag aggatcacgg
    32341 aagcaaccgg cttgccgatc catcggttta aatccggacc gttaggcggg gatcagcaaa
    32401 ttggagccat gatttcggag gatcagttag atttggtgat ttttcttcga gacccgctgg
    32461 ctgcacagcc ccatgaacca gatgtaacag cacttatccg tttatctgat gtctatgaga
    32521 ttccgttagc tacgaatatc ggaacagctg aggtgctact aagaggactg gaagccggct
    32581 tcctagattt tcgaagaatc gtccatgaaa tagacaagca tccactttca ttttgatgga
    32641 taagcgtatg gaaaaataac gtttaatgtt cgcctatatg tagctataaa agctaaacaa
    32701 actgataata tgcgatataa tacgaacgta ttggataata taaacaataa tattagtttt
    32761 tcgtatttgc agtaaatgtg aaaatatgct atagtttctg tgggaaaaga tcccaaaaat
    32821 aatacagagt agaaaataaa gcgttaagtg ctaagaggat gggatgttgc ctcttggacg
    32881 aaggacgtaa tgttcgcggt tttattttcg cattcgctgc atgatacgat gtagcagctc
    32941 ttaaaggaga tgctaaaaat gaagaaacac cggttagacg cacgtatgat tgctattatg
    33001 ggcttattga ttgcattgat ggtcactttg tcccgactgg tagcaatcga gaccccattt
    33061 attaaaatca gtgtcacatt tattccacaa gtgatcatgg gcattctttt tggtcctttt
    33121 tggtcaggga taggcgcagt tttagctgat ttagtaggaa tggccctctt ctcgaaatct
    33181 gcattcttta ttggatttac attgaatgca tttattgaag gagcaatcta cggattcttt
    33241 ttctatcgaa aagagatcac ttggaaaaat gccattctgg ctacgcttag tgtcacgctg
    33301 atcatcaact tatttttgac accattatgg cttgcgttga tgtaccatgt gccattgttc
    33361 agctgggtcg tttgggcgcc ccgcctgtta aaaacagtaa tatggttacc gattcaatca
    33421 attgccattt attacgtagg acgtagtatt ccttacaaaa aaattttaag aagtttagcg
    33481 atccacgcta aataaaaaac aagcagtctt cccatcccag aagactgctt gtttttattg
    33541 tgctgtgaat tgtgcttgat agagccgtcg gtaataacca tctttttgaa gcagctcatc
    33601 atgggtgccc atttcgacaa tagctccctg atccatcact aatatctggt ccgcattttt
    33661 gattgtggac aggcgatggg caatcacaaa actggttttt ccttccatca ttgctaagaa
    33721 ggcttgttgg atttttttct ctgtcaatgt atcgactgag ctggtagctt catctaagat
    33781 caacataggg ggattactga tcatcgttcg agcaatcgtc aacagttggc gttgtccatc
    33841 tgatatcttt aacccttgac cgccaatctt agtatctaat ttttccggca aacgttctac
    33901 aaattcatac atataagagg cttttagggc atcattgatt tctgcgtcac ttgcttccgg
    33961 attcccaaaa cgaagatttt ctcgcaatgt actgtcaaat agccaagtat cttgtaacac
    34021 cattccaaaa cttttacgta atgtatcacg ttggatagag cggatgtcat ggtcatcgac
    34081 tgtaattgtt ccttttgttg tgtcataaaa acgcatcagc aaattaacaa gtgtggattt
    34141 tccggcccct gtttttccta ctatagcaat ggtttgacct ggataagcag taaaattgaa
    34201 atcttcgatc aaacgctgct tggggtcata agaaaaagaa acatgatcaa aagagacttt
    34261 tcctttgata tttttgggtt ccaaggcata ggcatctggc aaatcaggct tttcttctgg
    34321 ctgatcgatc aaatcaaatg ctcgttctag accagaaaaa gcggtttgca gttgtgtcgt
    34381 gattccagaa agttcgataa atggtttaga aaactgactt gagtagatcg taaagctgga
    34441 aatcacacca acagtgattg acgaaccact cttcaatgcc aataggccgc caactaaacc
    34501 aatcgataaa taagcaaggt gatctacaaa acgagaagac gggtttgtca aggaagaaga
    34561 aaattgtgcc cgttgtcctt tttcatatag atcagcattt agcagttcaa attgctgttg
    34621 actagcttct tcttgctgaa aagctttcac gattttctgg ttaccgattc gttcggtcac
    34681 aaagcccgag atatccccaa taatcctttg ctgtctatcg aaatttgttt gtgaagcacg
    34741 agcaacgatc caactcacaa ggaaaataat tggtgtagaa caaagaacga ccaatgtcag
    34801 aagtggactt agacgcatca taaaaataaa cgaaagaatg atgattgcca ctccagaaaa
    34861 taattgattg aaggccgcag aaattgcaat ggaaatattg tccatatcat ttgtaaatcg
    34921 actgacgata tttccgtggg agttttgatc ataataacga agtggcaatc gattcagatg
    34981 agcaaatgca tcttttctta attttgcaac ggataagtaa gctaaccgat tgcttaacac
    35041 ttggatgagc cattgactga ctacgttgat taaaacgata ccaccgaata gaataagtaa
    35101 atggaacagt cgattgaagc ggacctgtcc ttctccaatc atttgatcga tactttgacc
    35161 aatttgtaac gtcatcacaa ctgttgcaat cccattgatg attcctagta tcacagctag
    35221 ccaaatgtct tttgcatagg cagtaaggta aggaatgaat cggcggagcg tctgcaagga
    35281 taattttttt actttcataa ctattcttcc tcctgtgatg cgacgatttc ctgatattct
    35341 gctgattgag caagtaattc ttcatgggta ccctgagcag caatcttacc ttgatccatc
    35401 actaagatat gatgtgcttc ttgaatagag cggacacgtt gggagataat aatcactgta
    35461 ctgccaagat aagtctgtag cgccttacgc aaatccaagt ctgtttgata atccaacgca
    35521 cttaaagagt catctaaaat cagtaatgct ggcttggcaa tcaaagctct tgcaatcgtc
    35581 agtcgctgtt tttgtccgcc agagaaattt ttcccatttt ccatgacttt tgtatctaaa
    35641 ccatttggaa gctgacggac aaattcttct gcctgagcga ttttcagagc ttcccaacat
    35701 tctttttctg tggcgtcttt cttaccccat tgaaggtttt cacgaatagt cccggtaaat
    35761 agtacagaag tttggggaac aagagcaatt tgctgacgga gatgatccag ctgccaagaa
    35821 cgaacatcca ttccgtccat tataactgta ccggaactga catcatagaa acgcggaatc
    35881 aattgtgtca aagtcgtttt cccgcttccg gttggaccaa tgattccaag gactgtattt
    35941 cgcttcagct gaaatgtaat attttggaga gaaagaccag aatcaggagt ataacggaag
    36001 tcaacatggt caaaagcgat aattgcttca gaagaaaaat cgggagtagt actgacctca
    36061 gcttcaagaa tcgaattttc tgtgtctagc acctctttca cccgatttcc tgaagcttcg
    36121 gcacgtgtga agatcacgac gaggtttgaa acaacgatca gtgccaaaag catttgattc
    36181 atataattga tcaaagcaag aacttgtcct tgttgcaagc taccaatatt tactttgatc
    36241 ccgccaactg tcagcaaaca gatgatcccg acattcatga tcaaggttgt agcaggtgat
    36301 aatagggcag agatattgga aacacgtaaa taattgttcg ctagatcatt tgtgctttta
    36361 tcgaacttct ctgtttcttt ttttgtctgc gcaaatgcgc ggatgacacg aacaccgcta
    36421 agattctgac taacgtgttc attgagctga tctagttttt cttgcacttt ttggtagaga
    36481 ggaacggttt ttttgatgat aaaaaataaa atgattgaga aaataggcaa taatgctaag
    36541 aaaaacagac ctacttccca gtcgatcaca aaagccatga ccactgaccc gatacttaaa
    36601 aacggtgctc tgatcaataa acgaatgacc attgctaaag ctagctgaag ctgattgatg
    36661 tcgtttgtca ttcgggtgat caaggtatct gttccaaaat gattcaactc gttgtgagag
    36721 aaagtattga tttttttgat tagctgatta cgtaactctg taccaaatcc ttgtgaagct
    36781 actgaagcat agtattggca aatgatagca caaatcagac caatcacaga catagcgacc
    36841 atccataagc ccatttcaat gatttttcct cggtcattca tttttagtcc attatcgatc
    36901 aaggaagcca tcattaaagg caggacaagt tcgaagacag cttcaagaaa tttgaagaac
    36961 gggcccaaaa tgatttgctt acgatagtct tttgcataac gtaataactg aatcatatga
    37021 ttcctcctat tatttatttg tccacaattg aaaaaacaag tactaccaca ttgtagctta
    37081 ggaaatttag aatgaaaaga gaacaagcct tttcataaat gaaagtttta ttatgaagaa
    37141 gctttagaaa ttgaatagac tatttttttt aaaaaaaaga aaatgagaaa acatgccagt
    37201 ctcttcattc ataggaacgt ctattttact taatttttct ataaatgaat tctgcataaa
    37261 aaatatatca agtaaatgtt tatagatgaa actctattta cttctttttt aatttgttct
    37321 tgcaatcttt tttgctacgt aatttttgta aaaaagtggg ttgagagaaa tctaattgat
    37381 tttcaaagaa ggagtatgaa aatgagaaaa atatttattc gtttattgtg ggtactatct
    37441 tagaggaata aataatagtg gagaaaacta tggtttggcg cagattctat caggtttgat
    37501 ggaacgaaga caacctcccg acatcaagtc aaaagctact tgagattttg atctgaaaat
    37561 aaaaaaagaa aacaaggtag gaacatcaat gtttctacct tgttttcgta atcaatggga
    37621 aaaaactaag agtggtgtac gtaatcaata aaaaggatgg tgacaacagt acctctttac
    37681 tctctgaaag catcataact cgtttttcct cattatgcca ataaattgtt gttataccac
    37741 atataaggat ttgtaatagc taaaaacaga caggaaagtt gaaatctgtg aatcttattt
    37801 tgtatggaag gatttataga acgcaaaaat caagataaag atgaataaaa atcctgtttc
    37861 ggctatatat tgcgtatcta cgccaataaa acgagtttgt tctgtcatag ccatataaag
    37921 caaaggcaaa aatacaacta cagcgagata agatccgatg atttctcgaa aagttttcca
    37981 ggaagtatgt ttcctgtttt tatatttatc cgatttcatt gaatagtcat agcctcctta
    38041 ttctttcata tgttgaaatt ccagtataaa aactggaagg aactgtacgt tttttagaat
    38101 aaaaattata agggataagt aggctgctgt ctataataag atatattttt caattcttta
    38161 ttaaagattt tattgacaaa atgaatccgt tttctatgat ggaggagggg tgaataagtt
    38221 gttgaagaag gaaattttat gttacttaga gaaccagaca gcctttttcg atttagaaca
    38281 tatgaacgag gtctttacag cacaaaggtt agctgatcat tttggggtaa aaagaaacac
    38341 agtcagtcat tatttgaacc agttaaatga tgagcaacta ctagtcaaaa tcaattctcg
    38401 accagtgatt tatttccaca aagaagcttt tgaaaaacaa ttttttaagt tacgcacgaa
    38461 tttttatttt tctatcgatg atctcaaaga ggaacagcct tttttcgcgc aaccaaaaga
    38521 cttattctct tttatgatcg gatacgacgc cagtttgaaa gaaagtatcg aacaaatcaa
    38581 aacagctctt tactatccag atggcggatt accacttttg attacaggcg aaagtggcac
    38641 aggtaaaagt tatttagtta atttggtcta tcagtattgt ctgcttcatg atctgctaga
    38701 agattctgca ccattcatca cttttaattg tgcacaatat gcagataatc ctgaactttt
    38761 gactagcaat ttgtttggac atgttaaggg agcgtacact ggtgcagaag aaaataaaaa
    38821 aggggctttt gaagcagcag atggtgggat cttgttttta gacgaggtac atcgcttaac
    38881 accagaaggt caggaaaaac tgttcaccta tcttgatcaa ggtgtgattt atcgtatggg
    38941 agaacctaat ttgtcacgcc ggatcaaaac acgtctcttt tttgctacga ctgaagagat
    39001 tactagtcat ttcttaacaa ctttcattcg aagaatacct atccgaatcg aactacctgc
    39061 acttaatcag cgtagtcgta atgaacggct agaactgatt tactcttttt ttctcgaaga
    39121 acaaagaaaa atggggagcc ctttgtcagt cagtggacca gctttgtcac ttttaacaag
    39181 tcagaaatta tccggaaaca taggagagct gaaaaatatc gtcaaagttt cagcagcaaa
    39241 agcatatgct gaacagcgtg aacagcctga aatccatgtc acgatccatc atttgcaaaa
    39301 agaactactt gcgcagccta ttactaaaaa tacagcacag caaggaatct atattacgca
    39361 agaccagacc ttagagcaat taatggagaa gcaacagccc gaacagcagc gaatcgttaa
    39421 aagttttgag caaatcctaa ttgatttcaa gaaaaataac tgtctgctat attcttgcga
    39481 aggaaaatta aagcaagaag tgattcaatt atttgatttt ttgctgtttg agaccagtag
    39541 acaagaaaaa cacgagctgc tggtttattg gacacaatct atccgagaga cctttcgaca
    39601 aatggaaact gcctatcaaa tcaaattcga tggaaacagt gtctatgcct tgagttacta
    39661 tctctatcag cgaagcacta tcaaatggtt accggaagaa catgatatta tccaactaat
    39721 caaagaatta gaacaacaag tttctcagtc ttatccatct agttatcact atgtccaacg
    39781 aattctggaa ttaagtaaga tcaaattaga tattgaagac acaagtatgg atcggatttt
    39841 actgacgatc tatctaaaaa aagcgaaatg gtcaaaagaa aaacgactgc caaaagcgat
    39901 gattgctgct cacggttatg caactgctag cagtatggca aatgtagtaa atcgtttatt
    39961 acaagaggat ctatttgaat catttgatat gccactagat gtcacaccac agcagattgc
    40021 ttcagaaatc cttgattatt gcgaaaacag cgatgtttca aatggattga tcatattagt
    40081 agacatggga tctctgaaag aaatccatca gttttttaaa aaacagttat ccgtaccgct
    40141 tttgattttg aataatgtga cgacaccttt agcaatcaca gtaggggaat gcctgcaaaa
    40201 aaatgtatca ttagaagaga tagcagaaga gactgttcga cagatccagc cagaatggcg
    40261 actgctctat ccagaggaaa acaaacccaa agcactcatt actacttgct tcactggaat
    40321 cggtacggcg gtccacttaa gtgaactgct agaaaaaagc ttacctacgg cttgtcagtt
    40381 gaaaatcatc ccatatgaat atcagcaatt aaaagataag aaaaacagtg acccattatt
    40441 ttccatatac gaagtcgtag gaatgattgg caccacagat cctgatatca ccaatatcga
    40501 ctatctttca ttagaagacc tcatctcggg ggaaaagatg tctgtactag ctgaatggtt
    40561 ggacactact atgaatgctt cagagaagga aatattcaat cagcgcatca ttcgtaattt
    40621 ttcattggaa aaagtactgg attccgtgac tattctagat acagagaagg tgatgggaga
    40681 aatcgatcat tttatgagag aattagaggt gcagttgaat cgaagcatca gcaatcccaa
    40741 aaaattagcg ttgtatgtcc atgtgagctg tctcattgaa cgattgatcc gacaaatgcc
    40801 aatcgaaacc tatcaaggat tagagaaatg gaagcagtgt caaaaagaag ggttatctgc
    40861 tattaaatct gcgtttagtg tcattgaaga gcattatagt gtcatgatcc ccaattctga
    40921 gattgcctat atctatgata ttttgagtga agatacagag tttctctcga tagaagaaga
    40981 attttgaaca taagcaagtt gttgccacta attttggcat gcaacttgct tttttagtat
    41041 gtgtaagtga aaagaggaga tgaaaaagtg gatagagaaa ttatcttagc ttcccatgga
    41101 aaatttgctt cagggatatt agattcatta gagctgatct atgggaaaaa tcattctatt
    41161 actgtattcg attgctatac tgatgagaat tttgatttag cggaaacagt aaggcagctt
    41221 tttatgaggt acaaagataa agaaatcatt gttctgacgg atctttttgg cggaagtgtc
    41281 aacaacgaat tcttacaata tatcaatcgg gatcatgtct atctcgttgc cggattgaat
    41341 ttgccactat tgattgagct agtatctcgg ttggacgctg aagtagagac aactgttttg
    41401 atccagcagg tgctaactga ttcaaaaaaa atgatccagt tttgtaacga gcggctcaat
    41461 cagaaaatag aagaagacga attttaggag gaagaaaaat gattgtattg acaagagtcg
    41521 accatcggtt attacacgga caagtagctt tttcatggac acaaacaata ggcgcagact
    41581 gtattttgat tgctaatgat gatgtaccta cgaatgagat acgaaagaca acgatcaaat
    41641 tagccaagcc acaaggagtc aaactagtga tcaaatcaat tgatgactcg attgccgcgt
    41701 tgaaaagcgg ggtgacagat aaatataagt tattcatcgt agtggaatcg atcgaggatg
    41761 catataagct ggcagaagcg tatccagaaa tcaaaaccat caacttagga gggatcaagg
    41821 caaaacctgg tactcgcagc atcggaaaag cggtaaatat tttaccagaa gaggaggaac
    41881 gcttgaaacg attaattgac aaacaaatag aagtagaaat ccgtcaagta ccagcagata
    41941 aaaaagtgga tgtaagagaa gttttgtaag aaaggaagaa cctcaatgat tgtacaagca
    42001 gtcttattag gaattgttgc atttgtcgca caatcagaat atgcactagg gacatcgttg
    42061 ctttctcgtc cgattgtgac ggggctgttt acaggaatcg tgttaggtga tgtaaaaact
    42121 gggatcatta tgggcgcaac tttagagtta gcatttatcg gatcgttctc agtaggtgct
    42181 tcgattccac ctgatgttgt gaccggtggg attttaggga cggcttttgc tattacagct
    42241 ggagccggta cagaaaccgc gcttttacta ggtttgccga ttgctacgtt gacattgata
    42301 ttgaaaaata tttacttagg gcttttgatt ccaattatga accataaagc agacaattat
    42361 gcagaagaag gaaattataa aggagtcgag catatgcact tgcttgccgg tatcggtctt
    42421 tccttgatgc ttggtgttgt ggtaatggtt tcttatatgg tgggaagcaa tacgatcgga
    42481 aatctattaa atatgattcc tgacttcgtt caaaaggggt tgtcagtagc tacagggttg
    42541 attccagctc ttggttttgc gatgcttgct cgtttgctga tcaacaaaca agttgcacca
    42601 tattttttct taggttttgc tatagcttct tacttagaga ttcctgtgac cggagtagct
    42661 atttttggtg cgattttagc agttgtggta gtcaatatta tgaatgtccg tcaactacca
    42721 cttcaaacaa ctgcagggga ggtagaagaa gatgaagaat tctgagatca aaaacagcaa
    42781 aataacgaaa aaagagctaa atcacgtatt ttggcgttct tttcaaatgg agttttcttg
    42841 gaattatgaa cgtcagatga atatggctta tgtttatgca atgattccga ttttgaaaaa
    42901 gttatatcag tcgaaagaag aaatggcagc agctttgaaa cggcatctag agttttttaa
    42961 cacgacccca catatcgtta cactgatttt aggaatcacg gctgcaatgg aggaagaaaa
    43021 taaggatgat cctgaatttg atgtgactgc gatcgatagt atcaaaacat ctttgatggg
    43081 acctcttgca gggttaggag attctttctt ttggggaact ttgcgattga ttgccacagg
    43141 tgtgggtacc tctttagcca tgcaaggaaa tattttaggc cctatcttgt tcattttgat
    43201 tttcaatatt ccgcacattc tgtttcgcta tctagcaaca ggttggggat atcgcttagg
    43261 aacgggtttt ttgaaaaaga tccaggcaaa cggtatgatg gaaagtttga cattaggcgc
    43321 gtctattatt ggactgatgg tcgttggagc aatgactgcc acgatgatca ccatcaatat
    43381 tcctttaaaa atcggttcag gagaaaatgc tgtgactgtt caaagtattt ttgatgatat
    43441 cgttccaaat atcttatgtc ttggagcatt tggcatagtg ttttatctat tgaagaaaga
    43501 agtgaaacca ttaacgatct tgatcggact agctttcttt ggaatttttg gttcgtggat
    43561 agggattttt taaaaaagga gcagagaaaa tgtttacgat gcaagattat atctatgaag
    43621 aaaaggaagt actaagtacg atcttgaaaa agaatgattt ttcgacaaga gaacatatga
    43681 aaaaaacagt gaatttactg atcttagcaa cgggttcatc ttataacgct tgtttagcag
    43741 cgaagccagc attggaatct tatggtgatc ttactgtcga tattcaagaa cctttttatt
    43801 ttttcaatta tggaaaactt tctccttcaa tcgatactgt gattgctgtg tcacaaagcg
    43861 ggaaaagtgc ttctactgtt gaagcagtaa aaatgataca aaaacaaggg ttacctgttg
    43921 ttgctatcac aaatgacgtg caaagtccac ttgctttaga agctgcacaa attattgatt
    43981 taggtgccgg ggtagaatca gtaggcttcg ttacaaaagg ctattctgcg actgttttac
    44041 agttactact cttagggata ggaattggaa taagtaaaaa taaaatcagc aaaaaaatag
    44101 aacaagacta catgcaacag ttgcgcaaaa taatcaacca tttaccagcg attattcaaa
    44161 aaacggaaga attttttgat ggatatcaaa gtttatttcg tttagcacag cgtttcgtca
    44221 ccattggata tggtccaaac tggggaacag ctaaagaagc agagacgaaa ttgactgaaa
    44281 caatccgcgt tccgtcacaa ggatttgagt tagaagctta tatgcacggc ccatacctgg
    44341 aggcagatgc ttcgcatttg ctattcttta ttgaagggga aagtgtaaat aaggaacgtt
    44401 cgcaaaagtt gcaaagatat atgagtcggt acgttggaga gactctcacc attaccacaa
    44461 aaaaagcaag aaacgagaaa acacttggat tagcaataga atgtgatgaa tatctgtctg
    44521 tattagcgct tgtcgttccg tttcaactat tcgcttataa aaccgcagta gctaaaggta
    44581 ttgacttgaa caaaaagatt tttgaagact ttgatacagt cttgaaaagt aaattataag
    44641 aggtggaaat catgctgaaa ttcaatgaag aagaacaaat caaagcaata aaaggcgcac
    44701 tagctttacg tccgcaagta gaagaaatca tcgataaact ttatgcggaa aaatttgacg
    44761 ctgtctatta tctaggaatc ggtggaacgt atgcttcctc gatgcaagct gtcacttata
    44821 tgaatgggaa aagcaacttg cctgtctttg tacagcatgc tgcagaatat tacactactg
    44881 gaaacaaaag attaacaaaa gattctatcg ttattttgtc ctctgttacc ggtacaactc
    44941 aagaagtagt gaaagcagta gaacaaatca agaaagtagg agcgacactg attggattta
    45001 tcgataaagc gaacagtaag ttgtctcagc tatgcgattt tgtggtcact tatccagctc
    45061 ctggaacaga acaaatcaaa ttttttatgg cagcagatcg attgatgtat ttgaatggag
    45121 aattcgaagc ttattcagaa tactatgaac agctcgaacg ttatttacca acagggttag
    45181 tggaagcaga gaaaaaagca gatgcatttg gcttatcatt tgcagaaaaa catcgacgtg
    45241 atagtatgca ttattttatt ggagcaggga atcaatgggg agctgtttat tcatatgcca
    45301 tgtgttactg ggaagaacaa agctggcttc catcgaaatc tatccatgct gccgagtttc
    45361 ttcacgggac gttagagatc gtagaagaaa caaccccagt cacattattt ttaggcgaag
    45421 atgaacagag agtgttatct gaacgtgtgg ctaaactttt gccaaaaatt tgcagcaatt
    45481 atacattgat agacacaaaa gactatccag tagaaggtat cagtgaaaaa tatcgcggac
    45541 gtgttttgtc tttcttattg atgcatgtag tgacacaacg catcgatgct catgtggagc
    45601 agttgaactg ccatccatta gagatacgcc gctactatcg tcagtttgat tattaggata
    45661 gactggataa aaagaatata aaaaataaag agagcagcga taactgctcc ctttattttt
    45721 ttaaaatatt ggcatcaatt acgttataaa acacattttt tgcattatct acagttcaac
    45781 ttataatctg tttaatggga catgtgggtg ccaaccattt tttgttatgc aatagtacta
    45841 tttagttgtt gcatggatcc gtagtaaaag tccaagtaca acgagttgcg ccagtttaca
    45901 tagcgttttg tatccagaat gttgactaaa acaaaagttc ctatgtcaac cgtcaacaga
    45961 gacaatctgt ccgttgcagg acctgacaga tttagaaatg ttcaatctgt ctcttatgta
    46021 ttttaaatca atactcacta ggagaagttt cctaacctcc taatagtaat gctggtagta
    46081 acattgtcaa aactgcttcc tcttaggaac aagcaaagca taacgagtgt aaaaataaaa
    46141 tgtagactat tgtaacatat cattgattat ttcaagtaaa aacgataaaa gaagtaaaca
    46201 aacacttaaa aacaatggaa attagtccca actttaagaa atgtatacta taatggaaat
    46261 tatcaattat ttatttggag gaatatccat gaaacaaaaa atcgcagttc ttggtcctgg
    46321 atcttggggc actgctttag cacaaacatt ggcagaaaac gggcatgatg tccgtatttg
    46381 gggaaatgta cctgaacaga ttgatgaaat caataagtat catacaaatc agcatttttt
    46441 acctgatttg acgatcccag aatcgattat cggatataaa gaattggcag aagcagtgga
    46501 taacgcagat gctattttat ttgttgttcc aacaaaagcg attcgttcag tcgcacagga
    46561 acttattggt aaaatgaata ctaagccaat cattatacat gcaagtaaag gactagaaca
    46621 agatacgcat aaacgaatct cagaagtttt ggctgaagaa attccagaag aaaaaagaca
    46681 ggcaattgtt gtattatctg gtcctagcca tgctgaggaa gtggcagtac atgatatcac
    46741 aacaattaca gctgcaagta ttgatcaaaa agcagcagcc tatgtacaaa aactgttcat
    46801 gaatgattat ttcaggattt atacaaataa tgatgtgatt ggcgtagaaa ctggtgcagc
    46861 actgaaaaat atcattgcaa ttggtgccgg cgctatccat ggattaggat tcggagatga
    46921 tgcaaaagca gcaatcatga ctcgaggatt ggcagaaatc agccgtcttg gtgtcgcgat
    46981 gggtgccaat cctctgacat ttatcggttt gagtggtgtg ggggacttga tcgttacttg
    47041 tacaagtgtt cattctcgca attggcgtgc cggtaacttg ttaggacagg gacataagct
    47101 ggaagaagtt ctagaaaaca tgggaatggt cgttgagggt gtggcaacga caaaagcagc
    47161 agtagagcta gctcaacagc taggtgttga gatgccaatt actcaaacaa tctataatgt
    47221 tttgtataat ggagaagata tcaaaaaagc agcaaaagaa atcatgttac gtgacggaaa
    47281 aatggagaat gaattttctc ttcgttaaat agatgatcaa tagttaatcg tcgtttagga
    47341 ggaacagcaa gtgaaggtca aaaaagcagt cattcctgcc gctgggctag gaacacgttt
    47401 tttgccggca acaaaagcca tggcaaaaga aatgcttcca atcgtggata aaccaacgat
    47461 ccagtttatt gtggaagaag cattggattc gggaatcgaa gacatcttga tcgtaacggg
    47521 aaaagaaaaa agacccattg aagatcactt tgatgcaaat atcgaattgg aaaacaattt
    47581 gcgggaaaag gaaaaaacag aattactcgc tttagttgaa gaaacgactc aagtcaatct
    47641 tcacttcatc cgtcaatctc atccaagagg actgggggat gccgtgcttc aagcaaaagc
    47701 atttatagga aatgaaccgt ttgtcgtcat gctgggggat gatttgatga aagatgatat
    47761 cccattgact caacaattga tgatggatta tgaagaaaca caagcttccg ctgttgccgt
    47821 catgcgtgta ccagaaaatg aaacatctaa atacggaatt attgatccta aaacagatag
    47881 cgaaaagggt cgttgcagag taaaagggtt tgtagaaaaa cctgaaatgg gaaaagcacc
    47941 aagtaattta gccattatcg gacgttatct actgactcct aaaatatttg agatattaga
    48001 aactcaagaa ccaggagcag gaaacgagat acagctaacg gatgcacttc agactcttaa
    48061 ccagacagag gcggtctatg cgagagagtt taaaggaaaa agatacgacg taggcgataa
    48121 gttaggatat atgaagacaa atattgaata tggacttcaa cattcggaaa ttgggacttc
    48181 attaagtgca tatattatcc agttgagtaa aaagctaaga acagaaagtt aactggaaat
    48241 aagtggcctg ctgagaatga aaggctattt gttattaaag cggcagcttg tgcgtcattt
    48301 gcgcaactgt cgttttagtt ttttgactct agatcagttg agtcgtggaa aacgaaagat
    48361 agaaaaagac tttcgtgaat agattcagaa aatattatgc taatggttta attttttttt
    48421 aagttgtata aaagaaaatg attacataag agaaatgaaa gccaagccag aagattcata
    48481 gtagaataaa aaggcgaatt ttttaattat aaaaaaaggt gtgtgttcac tatgggaaaa
    48541 ttagtcgctg ttgcacagtc gctgcttgat atactcaagt ggctgatgga aggaagcaat
    48601 tggatatttg tgttgccact attgcttatt agtctattta tcatgtttcg catggtcaga
    48661 aaaaaagaaa cgtttctgat ttttatctgg tatgcagcat ccgttggggt tgctaccttg
    48721 atggttgaat tggcgttagg tagttgggaa gcttgcgtat ttgctttatt ttttgctgta
    48781 ctgtatctaa tcatttatat cccatatatg aaaagaaagt ctcggatagg cagaaaaggt
    48841 agacatacaa ctactttttc tagtacagat tctctcgaac aaagtagaag aacgagaaga
    48901 agacggtaat atttagtagg tatacgcaaa aaaagataaa ataatggata aactattgag
    48961 atgagagatt tatttaattg gtggaaaaaa gcttttttca cttatataaa agaatctttt
    49021 ttaaaggaat gcttgttgta tcgggataag ccattccttt ttttatgtta tttatatata
    49081 tataaatcat accaatgttt ttttgtattt tcttgcttgc acttggataa gagattactt
    49141 acaataaatt cagatagaaa cagctgaata aaaaaaggct ccctgaccct tagttggcgc
    49201 taagaatcag ggaatgacca gtcacacaca tacaccctga ccgatcattt tgccatagtc
    49261 aatgcagtgc atcgacctaa tttattgtac ctaatctagg gtgaaaattc tacccctatg
    49321 tagatatttt ccatggtctg cacgttgttt tatttgctat gtcaaggtat tgggcgtatt
    49381 cgttcaatgc cttttttgtg tttgaaacag caaagaccac atgtgttact gtctaactac
    49441 tgttttttta tgtacttcct tagattaggc agctgtttct attcatgtca agtatagcta
    49501 ggcgggagag ataaatgagt ttatgttatt ttgactatta tcaccaattg gaagagaaat
    49561 taaggataga agagccgctg atgcttcaag ctggcacttg gatcgcgaaa caaattaatc
    49621 aaggtggtag attgcagata tatgctagcc gcacactaag tggtgtagca tttgaatttt
    49681 gggatcaaac cccggatctt gtaccaagta tattgattga aaatccagcc ggaggtgtct
    49741 atgaaacgct agaaggtgca ggacaggcaa ttattgatca gctttctgtc aaatcagaag
    49801 acatttttct tcttctttcg aatgaaggaa gaaacccggc aatcatcgaa ctagctcagt
    49861 ggatcaaaga aaatggtcat ccattaatca ttgttactgg atttgatttg tcacgaagta
    49921 tcaaatcgca acatagcagt ggtttgcgat tatttgaatt tgctgatttg gttttggaca
    49981 accacgccaa tttacatgat gcagtcttga ctttgccaaa tctagatcca gcgatctgcg
    50041 gaacagcctc tcttgcaacg atctttttgc tgcagcaagt tttgtatttt acagcaaaac
    50101 agctagtcca ggacacaagt ggaaaatagt tatccacatg ttgacaaagt tccttaaaaa
    50161 aataatgttc cacataaaaa tggagcgttt gaaaaaaaga aaacgattat taatgaggat
    50221 taacaacgac tacttttttt gttttagtta ttttaagatg gatcatcttt gattttaagc
    50281 ttgttttgtt taaagtttgt tatttttata agttgtttca cagttatgag aaatgagtta
    50341 taagaatatg tagtgtcaga aaaataaaaa gtagtggaaa aagagacaag aaagaatcca
    50401 tatggattct ttcttgtctc ttaatacacg ttgatgaaag agtcttcccc aaaactcttt
    50461 acaaagtaat tatagtacat ttgttatcat tattgcaatg aagtttacct gatataacaa
    50521 aattgtccaa caggatacct ttttctaata gaaataaaat acacaaaaat tgaaggatag
    50581 ataatggata tttataagtg tttattattt tttttgcaat gaaattcaat ttttcaatga
    50641 ttgtaaaatg aaaaaaacag gacgagattt tctctaatct aaaaataaaa aaagaatttt
    50701 aaggaaaaac agagaaataa aatacttaat ataaatggaa agagaaaaaa ataatcatac
    50761 ataggagaaa aaaaacaaaa tagaaaaaag tgattttcta ataaattatt catgtggaaa
    50821 tgtcattttt actgtataat tcatttgatt atccattttt tattcatcaa aattactgaa
    50881 aaaagaaagg aagaaataaa tttgaagaaa acaaattctt caggaaaacc gaaacgcgac
    50941 ttcactaaat tatcgacacc ccatacgtat gtcattattt ttggtgtagt catctttgca
    51001 tggatactga cttttgtcgt tccagcagga aagttcagca cgcaagatat tgaatacaaa
    51061 gatgcaaatg gcgaaacaag tactcgtact gttttacgtc aagattcctt ccgttatgct
    51121 tacgagctgg ataagtcgta tgtgtttgat caattagaag aactgcaaga tcatccagca
    51181 gaacgtgaaa aactggatgt tccggaaaaa ggattggaaa aagtcattgc tgacggagaa
    51241 aaaaatctta cgcaggaaaa actagatgaa atctccttga cagatgatgt gctttacgat
    51301 cagtacggcg aaaatatcta tgatacttct aaaaaattgc ataaaacagc caaaatatgg
    51361 ggaacagatg attttggcgg ctttggtttc ttaaattttg tttttgaagg actagtatct
    51421 ggagataagt atggatctgc tgtagggatc gctgcattga tccttgttgt tggaggtgct
    51481 tttggtatta ttatgcgtac cggagcgatc gacgcaggta tctatgcgtt tatcagtaaa
    51541 actaagggac tggagcgttt agctttaccg ctattattct ttgctttttc attcggtggc
    51601 gctacattcg ggatggcaga agaggtaatt ccattctcaa tggtgatggt tccatttgtc
    51661 attgcgttag gatatgactc gatcgtagca gtaaccgtga cttatgtcgc atctcaagtc
    51721 ggaaatgcga cctcttggat gagcccgttt agcgtagcgg tggctcaagg gattgctgga
    51781 atccccgtgt tgtctggtgc gacattccga ttgattatgt gggtagttgt tactgcatta
    51841 gccgctggtt atatgatgat atatgcagaa aaaatccgta aaaaaccaga aagttcgttg
    51901 acttacaaat cagatgatta tttccgttct catatcaaaa agacatctga tgaaaataaa
    51961 aaattcatgc ttgggcataa attgatctta ttagagatgt tagttgtcct tgtctggatc
    52021 gtttggggcg tgactcaaaa aggctattac attccagaaa tcgcttctca attctttgtg
    52081 atgggattag ttgctggaat cattgctgtt cttttcaaat tagatggaat gaaagtcaat
    52141 gacatcgctt cttctttcca atctggtgca gctgatttag ctggtacagc aatcgtagta
    52201 ggtatggcca aagggattct tcttgtcttg ggaggatctg atgcatctgt tccttcagct
    52261 ttgaatacga ttttgcatgg gatcgggacg gcgttgaccg gtgttccagc tgtcattggt
    52321 gcttgggcga tgtacatctt ccaaagtttg ttcaacttgg ttgttacatc aaattcagga
    52381 caagcagctt tgactatgcc aatcatggct ccactggcag atttagtagg tgtatccaga
    52441 caagtagcag ttcttgctta tcagcttggt tcaggtttta tggacgcttt tacacccgta
    52501 tcagccagct tgattggtgt gctaggtgtt gcacggatcg aatgggcaaa atgggcaaga
    52561 ttccaaatca agatgcaagg attcctgttt gttttaggaa ctattttcat catgattgcc
    52621 attgcaatag gtctgcagta gtactggaga cctgtaaata aaaaagtaat ccaaacagta
    52681 gataaggact ccaagaaccg tcattttacg gtaaaatcaa aggagtaaag atcctatcgt
    52741 ttggattatt ttttaagatc ctatcatcag ttatacttaa agaaagagga aaaatgtatg
    52801 aaaatcattc gacaaattga agtgtttgca ccagattact taggaaaaat ggatgtactg
    52861 attgccggtg ggaagatttt ggctgtagaa gaacagctag aaggcggcta cgaaggagtg
    52921 gaagtagaag aactttcagg tgagggaaaa gtactaaccc cgggtttcat tgactgtcat
    52981 ttccatattt taggtggagg aggagaaggc ggttatcaaa atcgaacgcc agaagtcaca
    53041 ttgagccaat tgactacagc tggtgtaacg acagttgtcg gttgtttggg aacagacgga
    53101 gaaggtagag atatgactgc gttgatcagc aaagcgaaag gtctggaagc agaaggaatc
    53161 tccacttatg tatacgaagg ttcgtaccga ttgccggtaa aaacagtaac agattctatc
    53221 atcaaagact ttttgacaat tgataaaatt atcggaatcg gagaaatcgc agtatccgat
    53281 caccgttctt ctcagccaag ttttgaagag ttcgctcgtg cagtagcaga tgctcgtgta
    53341 ggaggcatgt tatccggaaa agctgggatc atcaatgtcc acttaggcgg aggaaaaaga
    53401 aagctagagc tattgacacg aatcgtagaa gaaacagaaa ttccgatcac acaatttttg
    53461 cctactcatg caaatcgcac accagaatta tttgaagctt gcgtggcatt tgccaaacgt
    53521 ggtggcacga ttgacttcac tgctagcgaa gatcctgatt tttgggagaa gacagatggt
    53581 gaagttcgct tcagcaaagc actgaaacga ttgatcgagg aagatgtttc tttagataat
    53641 ttcacgatga cctcagatgg acaaggaagc ttgccttatt ttgatgaaaa caatcatttc
    53701 ctagggttag gagtaggaag tgccaaggca ttgctagtag ggatcaaaga agctgtgcaa
    53761 aaagaaagta tccctttgga aatcgcctta cgagctataa ccagtaatcc agcacgtata
    53821 ttgaaattgg ataaaaaagg aaaaatcgaa attggtgctg atgcagatct gtgtatcttg
    53881 gataaagaaa cgcttgatat tgatacagtt atcgctaaag gagaaataat ggtccaagaa
    53941 aaagaagtca aagtatgggg gactttcgaa aaaagttttt aatcaacagc tctaactatc
    54001 ttttttagaa aacgagcgtt ctgtttgtct gtatctgttg ttgatgttac cctgaaggta
    54061 gatcaataaa caaactaaga ggaggaagca caatggcaga tttaaaagga cgttctaaag
    54121 atatgaaaga taaagtagtc ggtgaaggaa aagaagcata cggcaaagca acagacgaca
    54181 agagcaaaga aacagaaggg aaagcacaat cactaggtgc tgacatcaaa gaaaaagctc
    54241 gaaatttagg cgacgaagtc aaagacaagt tttctcgaaa agacgaaaaa aaataaaaac
    54301 cacttattac taattgaatc aagcaaataa aaaatccgaa ccatatctgc gagacagata
    54361 tggttcggat tttttatttg atcattatcc tgttttttaa acttcgattt tttgaaattt
    54421 tttatttttt agttcaaaga cttcatcaca gctttttgct acttcaatct catgagtcac
    54481 gatgataata cagcgatttt gttcatgggc gatttcttgg aaaagtttga cgatatcttg
    54541 tgaagttgtt tcatctagat ttccagtagg ctcatccgct acgattagtt gatgttcaca
    54601 gcagatagca cgaacgatag cgactcgctg ctgctgacct cccgaaagtt tggtcacctg
    54661 tttttttgct aatatttcat caattcctac acgagccagt cgatctaaag caacttgtcg
    54721 ataattctct tgcttggtct tagtgatttc cattgctgct atgacgttgt ctagagccga
    54781 taaataagga agcaagttgt aagcttggaa aataatcgag acatcatttt tacgataact
    54841 tcttaacccg attttgttca gtgaacgatc ttgatagtat acctttcctt cttttggtgc
    54901 atctagtcca gaaataagcg aaagaaaagt cgtttttcca gaaccacttg ctcctaaaat
    54961 agcgtacatt tttccagctt cgaaattcag ttctacatct ttataaagcg catcttgcgg
    55021 atcttgatac caaaatccca attgttctgt ccgtaacatc aaattcctcc tttagtttaa
    55081 taggattttt cttgggttta atcttaatat ccctatagaa gctaaaaaga cagaaaacag
    55141 actgattcca aatgctactc cggctaatag tcccaattgt gcaggtttga cattgatttc
    55201 caattcgctg acttgatcag aaacagcaaa tggattattc gtggttcctt gttgaccatc
    55261 gcgttgaccg ccttgttctt gtctgttacc tggcatttgt ccaccgccag gagcttgctg
    55321 gttttgtgtc gtggtttctg tctgttggtc aagtagctgc tgtcccacgg cattcgcgac
    55381 gacgtttccg ctaagcgaag caactcctaa tgcaagaatc atacaaatag ccacttcggt
    55441 aaacaattgg agaatgattt tacttctgga ttctcctaaa gatagcaaga cgcctaactc
    55501 atgccgacgc tcccgaatgg taatcataat gatcagagta agtatgataa taccggctac
    55561 agccactagt aaaacaacat ttttagaaaa acttgccacg ttgtttaaag gttccaacat
    55621 tgactgatac atggaatcat ttgattgtaa gctaaatgta tctgtgtcga tcagcttctc
    55681 agcttctttg agaaactcat ccattttatc tggatcagat agagtgtaaa tagcagaatc
    55741 tatcgtgtta tcgtcagatg tcccatttag ttcatttgca aaagtgtaag aagtgtaaag
    55801 tgtattcgac ggattcatga agttgaattt catacccata ctgccgcttg tttcgctgga
    55861 ttcataaatt cctttgatcg tcatttcata agtggtatct tcatcttcag tactcgtgat
    55921 tgtgaaagta tctccgactg ccaggtcatt tgtttctgct agagtagaat caatgactac
    55981 attgtttgtg cctttgtcgc tgtcatctat tccttcacca tccgtgattt ttgctgttcc
    56041 atcagaaaaa ttactatttt gtgcagttgc tgacacacca ctgatttgaa agtctgcttg
    56101 agtcatttgc ggattcccgc ccattcctcc agcaggttca ccgcctgcat cagtagtttc
    56161 tgaactgtct tcacttgaat cagaactagt gatggcagtt attccatctt ttgccatagc
    56221 tgaggcggaa ctttcaaagg aataactctt tacattatct aattcagcta ttttttccgc
    56281 gtccgttaag gaaactggtg taagagaaaa actgcctgga tctggacgtt cttcagtggt
    56341 agaaccgctt gaagaagttt gttcctgttt tttaaatgaa gcttctcgat tggcacttaa
    56401 agtcactgtt gctccaactt ctttttgtgc ttgattcgct gcttcttctg cagcgcttcg
    56461 aatcgtgagg ccagctagca caaaaataag aatggctgtg aacacggcaa acaataacaa
    56521 tgaacgtccc cattttactt ttgtactttt ccatgcacgt ttcataaaat tcatattttg
    56581 catccctcct agtagatgca tttgataata gacaacctat cttaaagcta gcttaaatct
    56641 tatgctgttt gcacaccatc aacatgaggt tctgtatata taaaaagtca ctatagttat
    56701 tgcaaaaaat gtggtaaaat gaaaaaagta tgtttcaaac cgacgaagaa gaaatgaaag
    56761 aggaatagca aaagaaatcc tagatgctac agagggattt ttacgtgcat agttgttcta
    56821 acaattgctg atactagcga tttagtttat ttgttgtata ataatgggga acagctgaat
    56881 acttatataa gtattctggc tatagcgttt cgcaaaagat ccattttgtt aatgaagtat
    56941 atccaaaata aaatgcccat ccaactgtca gaacgcggat gtgctggtaa ttttcctgct
    57001 gattctccat aagttgagaa atagtgattt tgcatatgct tcattggaat ggctcatata
    57061 tttagataaa gaagaaaatc gacatcttta aacttggatg tcataagaag aggtgaagtt
    57121 tgtgagtacc attaaaatta tcccattagg cggcgttcgt gaaaatggaa aaaacatgta
    57181 tgtcgcagaa gtgggcgagg atatttttat tttagattgt gggctaaaat atcctgaaaa
    57241 tgagttgttg gggatcgacg tcgtaatccc tgattttacg tatttagaag aaaacattga
    57301 tcgtgtagct ggtgtctttt taacacatgg acatgcagat gcgatcgggg cacttcctta
    57361 cttgttgtca aaaatttctg taccagtatt cgggacagag ttgacgatcg agttagcaaa
    57421 attgaatgtc agtcgtaatg aagcagccaa aggatttaag gatttccatg tggtagatga
    57481 gcatacagaa atagactttg gtgaaacagt agtgagcttt ttccgtacca ctcatacgat
    57541 accagattca gtggggatca atctgaaaac aaaagaaggt agtatcgttt atacgggaga
    57601 ttttaaattt gaccaaacgg ctatcccaat gtatcaaaca gattatgcac gattggcgga
    57661 aatcggcaaa gaaggagtct tagccttact aagtgaatcg gcaaatgcag aaaatcctca
    57721 gcctgtagct tctgaagccc aaatagcaga tgaagtattt gatacgatca aatattggga
    57781 agggcgtatc atcgtcgctt gtgtagcaag taatttgcaa cgagtgcaac aagtattgga
    57841 tgcagcagaa aaagcacaac gaaaagttgt cttgactggt caagatttcg aacgaattat
    57901 tcgcacagcg atgcgtttag aaaaacttca attaccaagt gaagatctgc ttgttacgtt
    57961 gaaagacatg aaaaactatg atccagaaga actgatcatt ttagaaactg gccgaatggg
    58021 tgaacccatc aagtctctgc aaaaaatggc aaacggtaca caccgtaatg tcaagattga
    58081 agaaggagat ttggtttata tcactactac gccaagcatc gcgatggaaa ccatcgtggc
    58141 gaaaacggaa gatatcattt atcgagctgg tggaacagtg aagttgatct ctgagaatat
    58201 gcgcgtttct ggccatgcca atcctaatga cttgcaatta atgatcaatt tgatgaaacc
    58261 aacatatttt gtgccagttc aaggagagta tcgtgaatta gctgctcatg cagatttggc
    58321 tcatgcagta gggatgccat acaaaaatat ctatattact ggacgcggag acgtgctgga
    58381 atataagaac aagcgtatga gtgttgcagg aactacaagt gcagaaaatg taatgattga
    58441 tggattaggc ataggtgata tcggaaacat tgttttacgt gatcgaaaaa tcttgtcaga
    58501 agacgggatt ttcgtagcgg ttgtcactat cagtcggcga gaaaagaaaa tcatttcaaa
    58561 acctcaaatt acttcacggg gattcgttta cgtaaaagct agccgtgatc tgatgaaaga
    58621 aagcagcaat atgattgaaa caatcgttga gaaacattta gaaagcaatg attttgagtg
    58681 gagcaaatta aagcaagaca tccgagatca attaggccgt tacttatttg aacaaacaaa
    58741 acgccgccca gtgatcttgc cagtcattat ggaagctact caacgtcgaa ataaaaaata
    58801 aacaaaaaga gtaagatgaa cctctctata gagtgctcgt cttgctcttt ttttgcgaaa
    58861 aacaaataat ttttgaatac agcatccctc gctttataat aaacgataga ataaagggag
    58921 tgaatcaatg atgagtcaaa caaaagtcga acgttattta gaagaacaaa agatcagcta
    58981 tcaaccactt gattttagtc atgtggtaga agaatctttc acagaagaac tacaaaaaag
    59041 agggattgat ccagctttga tatgtaaaac tctcgtagtg aaaggaaaca aaactggggt
    59101 gatcatcgca ttgattcctt tgaacgatca cttagattac aaaaaaacga gacaagtgac
    59161 gaaagatcgt aaagttggtt ttcctggaat ggattttgta ttaatgcata caggatatcc
    59221 ccacggagca aacaccccta ttggaataaa actcgcacat cctgattatt gttttttagc
    59281 agacagttct ttaaaagaaa aagaagaagt aattgtgtca agcggtgaaa tcgggagaag
    59341 ccttcggata aaagtagccg atttagaaaa gatcgtccat cctatttacg ctgatttaat
    59401 tagttaaggg acgagaagag aagctaagca gagcagagac ctcaaacttg agattatatc
    59461 tgcttggtac ttggtgcatc ctgtattatc tgttacaatt gctttgtaca tactgtacta
    59521 tcaatccaat gaaaatatat ttagcagcta tattttttca ttgatgtgca agtgatgaaa
    59581 tcgtttttaa taaaaaagat acagagaaaa cgcgaggtgt aaaatatgaa aattacgtat
    59641 catggacatt cctgtttaac aattgaaatg gaaaatggcc aacgcgtgat gattgacccg
    59701 tttattacag gaaatccatt gacagactta actgcagaag aagtaaagac agattggttg
    59761 ctgattactc atggtcatag tgaccacata ggagatatga ttcctattgc aaaagaaaat
    59821 caagccacaa ttatcagtat tgttgagatt gctgattatg cgaacagcag aggagtagat
    59881 tcattcggta tgaatatcgg tggaaaacat gcgtttccat tcggcgtggt aaaattcgta
    59941 catgcacagc atagttcaag ctatgaagta gacggtatcg ttcagtatat gggcgagcct
    60001 agcggaatta ttattcaagc agaaggaaaa acgatttatc atgcagggga tactgcttat
    60061 ttcagtgatc taggattgct tgcagaagaa ttcgatattg atgtcgcttt cttgccgatt
    60121 ggcgataact atacgatggg gccagaagat gcagcaaagg ctgcgcaaac aattcgtgcc
    60181 aagaaagtag ttccaatcca ttacaatact ttccctgtca ttgaacaaga tcccgaatct
    60241 tttgtagagt tactggaaga tagtgaagga aaaataatga gcgtctcgga aacgctggaa
    60301 gtgtaggcag aaaatggcga caaaacatga tttgatttta gaatatattg aaagtttacc
    60361 tgttggcaat cgaatttctg taagaagcat cgcaaaagaa ttgaatgtca gtgaaggaac
    60421 agcgtaccgt gcaatcaaag atgcagaaaa tgtcggacta gtttcaacaa ttcaacgagt
    60481 agggaccatc cgtatcgaac gcaaattaaa aaaacatatt gaacgtttga catttggcga
    60541 ggtcgtcagg atcattgaag gggacgtttt aggcggggcg gcaggattag acaaggtctt
    60601 gaataaattc gtcatcggcg cgatgactaa acatgccatg gaacgctata ttacgccagg
    60661 atcactaatg atcgtcggca accgggcgga agtccaaaaa ttagcattgg aagatggcgc
    60721 cgcagtattg atcacaggag gattcaatac gactgctgag attgcaaagc tagctgatga
    60781 tcttgaaatg ccgatcttac gcacctctta tgatacattt acagtcgcaa ccatgatcaa
    60841 ccgagcgtta agcgaccaat tgatcaaaaa agatatcatg cttgtcagtg atatctatat
    60901 gccagctgaa aagactcatt atttgcagca gacagatacg atttctgatt atcagcgttt
    60961 gtcagaagaa acgcagcatt cgcgttttcc agtcgtcaac cgccatcatc gtttgatggg
    61021 gattgttacg gcaaaagatg ttttagggaa atcgccaaac cagatcatcg atcgggtgat
    61081 gacgaaagaa ccaatcagtg taaagaaaac aatgagtatt gcctctgtta gccatcaaat
    61141 gatctgggat gggctagaag tcatgccggt cgtttccgat gacttgacat tggaaggctt
    61201 gattacccgg caagatgtaa tgaaagcgat gcagcttgtc cagcgacaac cgcagattgc
    61261 agatacgatt tcggatcaga tatctggaaa tatccatacg attgatactg accgtgaagg
    61321 aaatcgtttg gaaaacccta agttcaaatt cgtagtagca ccacaaatgg tcaatggcgt
    61381 tggaaccatt tcttttggcg tacttagcga aatcatttct gatgtcgcac aaaaaacaat
    61441 ggtgatgaac caaaaacgaa atatcttgat tgaacaagtg aacctacatt atttgcggct
    61501 gatccaattg gaaagcgaat tagacattcg tccacgtgta ttggaaatcg gcagacgttc
    61561 cgctaaactg gatatcgaag tgtttattga aaacaccatc gtttccaaag caatcgttgt
    61621 ttgtcaagta atggaacgtt cttagaaagc aggagtgaaa tgacagtaca gcaagaaata
    61681 gtagatacaa taaaaaaata cgataaaatc attatccaca ggcatttgcg ccctgatcct
    61741 gatgcattag gatcacaagt aggattagcc gaactattac gggaaagttt cccagaaaaa
    61801 gaaatacgtc aagtaggtga aacgattgaa gggcttcgct ttttagcaga aatgcaagaa
    61861 gttgaagatg tcttctacca aggagcgcta gtcatcgtga ctgatacagc taattcaccc
    61921 agaatcagtg atcaaagata tcagttggca gaaaaactga tcaaaatcga ccatcatccc
    61981 aatgatgacc cttatggaga tcttgtgtgg gtaaatacaa aagcaagtag ctgtagtgag
    62041 atgattgcag aatttgcttt gatgtttcct gaatctttaa agatgaacgt taaggctgca
    62101 cggttacttt atgcaggaat cgtcggagat acagggcgct ttttgtatcc ctccacgacg
    62161 tcccgtacat tagagattgc ttcgatattg agaaattatc catttgatgc aagtgctttg
    62221 aacagagaga ttgaacaaat gccgatgaaa gtcgctaaac tttccggtta tctttatcaa
    62281 aatatccagg tggatgaaaa tggtgcagga agaataatcc ttccgcaaga aattcttgat
    62341 aaatatggaa tcgatgattc agagacagct tcgatcgttt cacttcctgg agtgattgac
    62401 gaagtgctgg cttgggggat ttttgttcag cagccttcag ggtattaccg cgtacgttta
    62461 cgttctaagg ggccgatcat caatgaattg gctaaacgcc atcatggagg aggccatcca
    62521 ttagcaagtg gtgcgaatgc aaaagattta gcagaagtag aggaaatcta taaagagatc
    62581 caagatatat gccaatcgta taagagcaga aaaacagaat gatacttcgt tcgaaaacgt
    62641 gccttttgta gtaaaaatca caaatgtatc ttttcaagat cttctttttc cgttacaata
    62701 gtgctcacta aagattttaa aggagaaaga agatgacatt accaaattgc ccagaatgtg
    62761 gctcagagta cacatatgaa gatcgaggct tgttgatttg cccagaatgc gggaacgaat
    62821 ggaacaaaga agaacaagaa actgtcatag aagacggatt agtggtatta gatgcaaatg
    62881 gaaaccgtct gttagagggc gatagcgtga cagtgattaa agacttgaaa gtaaaaggtg
    62941 cgtcaggtgc cattaaacaa ggaacaaaag tcaagaacat ccgtttagta gaaggcgatc
    63001 ataatatcga ttgcaaggta gaaggatttg gaccgatgaa actgaaatcg gaatttgtga
    63061 aaaagaatta aagaatattc aaggtctttt cacattcttt tcctactact aatgataaaa
    63121 taaagtaaac gaaaaggagt gaaacgaaaa tgtatggtta tggaatgtat ggttttttag
    63181 atccgacatt tcttttggtc attcttggat tagttatttc cggaattgcg tcagcgtacg
    63241 tcaatagtac tttccgaaaa tacgatcaag tgagaagcaa aaacaatgtg actggtacac
    63301 aagcagcaca atatatatta caaagtcaac agataaataa tgtcggtgtt caacaaattg
    63361 ccggagatct cacagataac tacaattcag gtaataagat gttgagtttg tctcaagcaa
    63421 ctgcacagtc tacttcagtt gctgcgatag gtgtagcagc tcatgaatgc ggacatgcgg
    63481 tacaagatgc ttcgggttat gtcccattga agattcgtgc agcacttgtt ccagcagcta
    63541 actttggttc gatgatttcg ttccccttga ttatggtagg tgtattgctt agctggaact
    63601 ctacgttaat caatatcggg attttcgctt tttctttagc attacttttc caattggtga
    63661 cattaccagt cgaatttaac gcgtctcggc gagcaatcca aattttgagt gaaggcggac
    63721 tactgacgga agaagaagta ccgatggcaa gacacgtatt atttgcagca gcactgactt
    63781 atgttgcagc agcgctttcg acattcctgc agctgttgcg cttgatctta ttgttcggcg
    63841 gcaaccgaag agattaaaat aaagaagttg tgaaatcagc gctttgatct gagctaatac
    63901 cgagagttag ctgattgaat accatttatt tggaataaga ggatgtgaca agaattttgt
    63961 cacatcctct ttgttttgtt ctcataacct tttttcatat acagttcatg aaccgctttt
    64021 attaacttgc caaataacac tgtattgtgc gttgtatcca gatagaaagt ctccgtttca
    64081 tctgaaattt tctcatgctg atctgtaatg atcaaatcag catgttctga atatgcggta
    64141 attttaacag catctttgcg aaataactgc tgcaaatggc tttgaagatg ataatttcct
    64201 gtaaactgtt tggttatctg caaatggatg agtaactgct ctttcgtttc tgtttgtagt
    64261 aagtgttgga tcaattgact aaggtattga ctgatttggt ttctttcccc attttttgaa
    64321 aaaattgtat cgattttttc tcttaatttc ttttcctgta taaaagaact agaatgattg
    64381 gacgtggctt ctggaaagca aagtgtagaa aaactactgc tggattcacc caacagttcg
    64441 aaaaaaacaa ctgccaacac aagaaaataa aaataaattg gtattttatt ttctaaatgg
    64501 ttgagaggaa actgttgagt taagtaagtc atcaattgac cgacttgtcg acaaataagg
    64561 tttttgcttg tggaaaataa aaaaccaatc tcctgttttt gtcgaaaaga gatttgattt
    64621 ggaaaaaaac aatagaaaaa ataattaaag taggctctct ctgtttctgt ctcttcacaa
    64681 gggcgactca ctgaaaaaga agtaaagtat tctgaataat catgtgtatg ctgcaataag
    64741 tccatcaatt cagtgatttc agaagaagtt tttggaaaat atgcctgttg tttgtttcgt
    64801 aatatgaata aagttaacag caagtagata tttttttctt gttttgaaat tttttctatt
    64861 tgctcatctg tactgttcat ttttagtgca tttaattcaa gtgaggaaaa tggccaatcg
    64921 ttacctccaa atgtatctga aagaaaaaag taaagataga gacggataga taactcattt
    64981 ccttcaagag tacagcaatt ttttacagat aggatccgta aatggaattt ttttaaggaa
    65041 tgattgagct gttttgtcag tttttcgaga taggagggcg atatataaag ttgttcaagt
    65101 aaatattttt ttggtacagc agtttgtgga taattgatta gtaacatcaa atagttaaaa
    65161 cgattggatt cttttaggta gcataatttt aacttagaaa aaacagctaa ctttttagtt
    65221 tgatcggttt ctttggtttg gatctctcct ttatgattag aataaataaa ttcatcaatc
    65281 aataaaaatt gcttgagtga tacatttatt tttcggatca gttctttgat tgtccgtttt
    65341 ggaatatgta agtcattgga taattcttgt aaagaacaat tatttttttg aatgaccatt
    65401 tgtagaacaa gtaactcttt ttttcttgct tcaattagca taaatacctc ctttttattc
    65461 tgtttttgta tatagttaga caaaaactgt gagtggaaag tcatttcagt ctgtgttatt
    65521 ctcacagagt gtcgccttct tttttatata acgttattta atttttttgt taccttgttt
    65581 attctattgt ttatttccta gggtattttg tcaagatatt cttgttttta aggcggaaaa
    65641 attgattttt aatggatata actaaatatg ttttgataat tatcaataat atttttagaa
    65701 ttatttatgt tatttattta tgggtagatg aaaagagacg gaggtaagaa tgatggggag
    65761 agtaacaaat tatagtaaag aatatttgct gttcaaaagt atggtatacg tggaagaata
    65821 tggaatgaag tcaattactg caagagagtt agcagagttc tgcggttgtt ctacataccc
    65881 gatttataca catttcaaat caatcagcgg gttaaaagag aagatattag aagaaatcac
    65941 tgtttatttt gaaaactact tagctgaatg cagttccgat gatgttttaa gcattgtcta
    66001 cttattgaaa gatttttttt ctatccatga aagtattcgt gaaatcattg caaaatctga
    66061 tttagacatg gattcgctat ttaagcggcc atttttctca tatgtcaaag gtcacacgaa
    66121 gatcaaagaa gaaaagtcgc ttgaattggt atggcttaat gcattgggaa gtttgcgctc
    66181 agatgattct tctcaagatt ttcttgaaat gatgaacgct gtttgggata aaaacgaggt
    66241 gacggatgaa tacttggaaa atatcttaaa ggaacagtca ccttaggcag caacatgaaa
    66301 aagtagatca gccaccttta tttttcgtaa aaaagattgt aaaatgtcta acgaaacatt
    66361 ggaatgaagg aggaagcgac aacgttacca cagcaattta tcaaaaaata tcgtcttctt
    66421 ttaggcgaag aagcatccga ttttttttct gcgcttgaac aaggaagcgt gaaaaaagga
    66481 tttcggtgga atccactaaa accggcagga ttggacatgg tccaaactta ccatagcgaa
    66541 gaattacaac ccgctcccta cagcaatgag ggatttcttg gcactgtcaa tggaaagtct
    66601 ttcctccatc aagctgggta tgaatatagc caagaaccaa gtgcaatgat cgttggaaca
    66661 gctgctgcag caaaacccgg tgaaaaagtt ttggatttgt gtgcggctcc cggtggtaaa
    66721 tcaacccaat tagctgctca aatgaagggg aaagggttat tagtgacgaa tgagatcttt
    66781 ccgaaacgtg cgaagatttt atcagaaaat atagaacgat ggggagtttc gaacgcaata
    66841 gtgacaaatc atgcacccgc agaacttgtc cctcattttt cgggcttttt tgatcggatc
    66901 gtggttgatg ctccttgttc aggagaagga atgttccgaa aagatccaaa tgcaataaaa
    66961 gagtggacag aagaatctcc gctatactgt caaaaacgtc agcaagagat tttgtcttca
    67021 gcaataaaaa tgctaaaaaa taaaggacaa ctgatttatt cgacttgtac gtttgcacca
    67081 gaagaaaatg aagagatcat tagctggctt gtagaaaatt atccagtaac gattgaggag
    67141 attcctttga ctcaatccgt tagttcagga cgttctgaat ggggaagcgt agctggtttg
    67201 gaaaaaacaa tacgtatatg gcctcataaa gatcagggtg aaggacattt tgttgcaaag
    67261 ctgacttttc atggacaaaa tcagatgcat aaagaaaaga agacacgaaa aaaaagtaaa
    67321 gtgcaaatga caaaagagca ggaaaaactc tggacggagt tttcaaatga ttttcattat
    67381 gaagctactg gaagactttt agtgttcaac gaccatcttt gggaagttcc tgagttagcc
    67441 ccttctctcg atggtttaaa agtcgtacgt acaggtttgc atttaggaga tttcaaaaag
    67501 aatcgatttg aacctagcta tgcattagcg cttgctacaa aaaagataga gaatatacct
    67561 tgcttgccga tcactcaaaa ggaatggcaa tcttacacag caggagaaac atttcaacgt
    67621 gatgggaatc aaggatgggt tttgctagta ttagataaga tacctgtcgg atttgggaaa
    67681 caagtaaaag gaacagtaaa gaactttttc cctaaaggat tgagatttca ctgagtggat
    67741 tagttcgttt atttttttgt ctatgctatg atggagatag ataaaaagga gctgatactt
    67801 atgaaaacat caacaaaagt aacaatcgga ttaagcgtag cagccgctgc cagtgtagcg
    67861 acagcagtcg ttgtatcggg aaaagtaatg gaaaagatcc atcatatgac tactcggacg
    67921 aaagtaaaaa aattcgtcta tgacaaattt gatggaaatg aaaaattact agaaatcgta
    67981 gatggtcttt cagatagtga cttggattct ttgatgggaa tgttagcaaa aatcaaatca
    68041 ggaaaaaaga aaatctctgt ttatggtgat tcaatcaaag attcaaccga agatgtaaaa
    68101 gaccggctaa tgcattttgt tgaaaaaatg atgtaagaga aactagcttt tgaacactat
    68161 tcattcgaaa taaggggttg tgacaaaatt attgtcacaa cccctttaat ctatctttaa
    68221 ttatgttcat gaagcaataa aagatagcaa aacagtaaat cgttggcttt ttttagattg
    68281 aaaccagact gttcttgaaa tttttcgatt cgatatttta gagtattacg atgaagaaac
    68341 agtgtttttg cagcagagct gacattgcct aattcattcc ataattcttg aatgatcact
    68401 tccatttcat tttgtttgat cagttctatg taacttttga tcaacttact atcttttaca
    68461 gtatcttttg tatagtaatg taaagccaca tcttgcatag aaaaagtacg gctgtgagta
    68521 taaagattgt tttgctctgt taaaaaaatt tttctttctt cagcaaacaa agggacgagg
    68581 tcggtgccag gtgaatggaa agaaccaacg aatacagacg ttgtcgtatc aaaatcagca
    68641 tctaaagata gaaaaatacc gttgatttca gtagcatcaa gataatcacg gtttatttgt
    68701 tcgactaaga gcgcatctgt gtctgtataa aaaaagaaat cagcagaata gcgaaataat
    68761 tccaaaatag tatcttgcca ttcttttttt aagaattctc cttttgattc gacgtgaagc
    68821 tggatcaaac gaaagctttt ttcttgaaca caagaagcat ctttaaaaag atagtgatac
    68881 catgggtgtt ttttttgatc gttgattaca gggaataacg ctttcaaaag gctggtttct
    68941 tgttgagata atgaatcttg tttgatccag ataaaagcat catcaattgc aaaagaaagg
    69001 atatccgctt ctgatgctgg agagtttttt ttctgtgctt gtgggtaaag agcaagtaat
    69061 ttatccattt tcatcttgtt cacctcttgt atttatttta ccatagaaaa aaaagttagt
    69121 tacagccttt ttatcatatg ctaaagtaaa acaagaaaaa acaaaggcag ggaagggtaa
    69181 ttggtaaata caaatcttga tgcagtagaa aaagaaaaat ggatgcgcct tgcattggca
    69241 gaagcaaaga aagcagaaat gcttcatgaa gttccgattg gagcagtggt tgtattggat
    69301 ggaaaagtga ttggaagagg atataacctt agagaaacca cgcaagatgc tactacacat
    69361 gcagaaatgc ttgcaatcaa ggaagcctgt gaaaaagtgg gaagctggcg cttggaagat
    69421 gctgcacttt ttgttacctt agagccttgt cctatgtgca gcggcgcgat gattttgtct
    69481 cgtgtagcag aagtttattt cggcgcgtat gatccaaaag gcggaacagc cggtaccttg
    69541 atgaatcttt tggaggacga gcggtttaac caccaagcat atgtagaagg tggcatttta
    69601 gaagacgaat gtgggatgat tttgactgac tttttccgaa agctccgcca gcgaaaaaag
    69661 aaattaaaaa aagactggtc aacgaatgaa aaataaggta tactattctt tgccgaaagg
    69721 ctaggacaat ggtgggcttg tgaagcgtgt caggtctgga aggaagcagc actaagcagg
    69781 ttccgccatg tgtctgatta taatgaaacg acaacagact ttcgggtctg ttttttttat
    69841 ttttatagta ctgtaaaaat gaatgttcct gattttttag ccagactgat ttatcgaata
    69901 ttgtacttat acaatttgct tcaaggcagg aaaaactctg aaatagagct tgtttcaatg
    69961 gaagaaaaag ctgcctatgg tatgataaag ataaagagag gcgagagggt acatggaaaa
    70021 aatagtgatt ttacatacga atgatctgca ttctcattta gaaaattggc caaggatcag
    70081 aaggtttttg gatcaacgta aacgagaaaa cgaaaagaaa gaaaaaacga caacgattgc
    70141 agtagatcta ggtgattttg tggatcgttg gcatccattg tcagaagcaa cgaatggaca
    70201 ggaaaatatc ttgctgatga atgaagttgg ttatgatgca gcgacgatag gaaacaatga
    70261 aggcgtagga aattccaaag aagagttgaa tcatttatac gatcatgctg agtttgatat
    70321 catcctggat aacttattcg ataaaaatac gctccagcca ccggcatgga cgaaaccata
    70381 taaaatcatt acaacgaaac accagacgaa aatcggacta attgcattta ctgctccatt
    70441 tccgcttact tataatccga atggctggga catacggaat ccttatgata ttttgccaga
    70501 attagtcgaa gatttacgtt cacaagtgga tgttttagtt ttgatgagtc atctcgggat
    70561 tcaggatgat ttccaaattg caaaagaaat accagcaatt gatgttattt taggatcgca
    70621 cacccatcat ttattcagag aaggtcacgt aatcaatgat gtccaaatag cagccgctgg
    70681 aaagtacggg cagtatgtcg gtgaagtcca tttaaccatc gatgaagaga aaaaaatcct
    70741 taagcattca gccaaagcca tccctaccga aacaatgaca gcttttacag aagatgaaca
    70801 agaaataaat agttatctag aacgtgggca tgaattatta aaagaaaaag aagtagcaga
    70861 tttgccattt tctctgagtc tagatatctt caatgagcat tcgtttatcc aagtagcctt
    70921 tgaggcggtg aaagaacgag gaaagacgga agcagcaata ttaaacagtg gtctgttttt
    70981 aactgaaatt ccaaaagggc gggtcaatca ggatcagctt cacactgcgt tgccgcatcc
    71041 gatgcacttg ttaaatgtca cattgggtgg aaatgatctg atccgcttag ttttagaaat
    71101 agaaaaaaat cgtaactttt tacgtaacta tcctatgaag ggaatgggat ttcgcggtaa
    71161 gatttttggg cagatggtct ataatggaat cacatatgat tctattaacc atcaagtctt
    71221 ttggaagaac aagccaatcg atctgaataa aaattatact tttactaccg tagatcattt
    71281 gatgtttgtt ccattttttc caacgattga gattgctgga aaaaatgaat ttttgttccc
    71341 tgaatttatc cgaagtgtgg taggagatta cttgaaagct cactacccaa tcaaataaaa
    71401 acaaggtata ataaaaaaga taggtggtga acgcatgtct gcaaaacaaa atgaacagca
    71461 gaacgttgag cataaaacag aaattgctaa gaaaaaatca tcagctgaac aggaaacaac
    71521 agtcaccgaa gaactgacag ctgctttgga agaaatcgtt gaggagccta aagcagaaaa
    71581 agtcaaaggc gagctagtga cactgttaga tgacagtaat tttttgatag gtgaaagaca
    71641 ttatcggctt gtgtccgatt atcgtgaagg atttaatgca gaaaagcttg gagaacgtta
    71701 cagtgatgta ctagcccgat atgattatat cgtaggagat tggggttatg aacaactacg
    71761 cctaaaagga tttttccaag cggataatcg acgggcgcat ccagatcagc gaatcgattc
    71821 cttggaagac tatctttacg aatattgcaa ttttggttgt gcgtattttg tcatcgagag
    71881 aatcggcggt aaaaaagaaa agacaactca gcgccgaaaa aagaaaaaaa accataatcg
    71941 tgcgtatatc gatgagaaaa aaggaccagt cgcatctaat cgcaaaaaac cggttattaa
    72001 aaatcgaaaa acagagtcag caaaaacctc tgaaaaagta aaaaaacaag aacaacctaa
    72061 acaagtagaa aaaacaaaaa cagcatttac gatcagaaaa agggaagagt agtggatgaa
    72121 tggactataa aggatattta attgatttag acggaacgat ttatcgtggg acacaaccca
    72181 taccggccgg taaacgattt gtggaagaat tgcaaaaaag aaaattacct ttcttgtttg
    72241 ttaccaataa cacgactaag tcaccagaaa cagtagctaa tcgtctagca gatgagtttg
    72301 acattcatgt agctccagag acagtctaca cagctacttt ggcaacaatc gattttatga
    72361 aagcagatgg aaaagggaaa aaagtctatg ttatcggaga agcaggattg attgacttga
    72421 ttttagctgc cggatttaca tgggaagaag aggctcctga ctatgtagtg gtaggcttag
    72481 ataattatct gacctatgaa aaagtagtta aagcaacact tgctattcaa aaaggtgcta
    72541 ctttcattgg aacgaaccca gataagaata tacctactga acgcggcctt cttcctggag
    72601 cagggtcagt catctctttt gtagagacag caacccaaac gccgccgatc tacatcggaa
    72661 aaccagaagc catcattatg gataaagccg ttgaagtatt agggctgcaa aaagaagaag
    72721 taatcatggt tggagataac tatgaaacag atatccaagc tgggatacgc aataatatag
    72781 atactttgct cgttttatca ggttttacaa aagaagaaga tgtacctggg ttgcctatcc
    72841 cagctaccta tgtgaaacaa tcactggatg aatggagctt ctaatatgaa aaattcgaga
    72901 tggcagtgga tggaatatgc tggattgttc agcctatttc tgacactgat cagtctggca
    72961 gttggtgtga cgatcaactt tcgaccacta tacgtatttg atatcggaca tttgcaaatt
    73021 ttggattata cttctttaga tcaagagacg ttactgaaaa attttgatca cctaatgaat
    73081 tatctcaata atcccttcaa aaccatcctc agcttgccag atttcccagt ttctgctagc
    73141 ggagcccatc acttttatga agtgaaaatt ttgtttttag tggattatgc tgtgtttttc
    73201 atcactttga tcccgagtat tttgtttatc aaatatttgc aaaagaatga tcggctttgg
    73261 cggttgattc gtccgtttca aatcggcatg ttactgccag ttgttttcgg ttttttcatg
    73321 atgataggat ttgatcgctt ttttatcctt tttcatgaaa cgtttttcaa caacgatgac
    73381 tggttattcg atcccgttac tgatccaatc atcaatgtac ttccagaaga atttttcatg
    73441 catagcttta tcttattttt tgtattatta gaattatttt ttgctgtttt tcttttctta
    73501 ggaaaaaata gcttgaaaca aacaaaaaag aaagaactcg tctaaataga cgttttcttt
    73561 ctttttttgt tgaattattg agtaaggcga cttctttttt ctggttcttt gtgtgctaat
    73621 cgactggcag cagcagcggc gatcgctccg acgatatcat ctaagaaggt atggacatga
    73681 acgccatcgt ggctgtttag ttcttttaaa ataccaggtt tcaccttgtc gatataacca
    73741 taattcgtaa agccgatcgt accgtaaaca ttcacgattg acaaggctag gatctcatcg
    73801 ataccgtaaa ggccttcgtc atcttcgata atatgttgca acggactcat caattttttc
    73861 ttttctgcta atatatctaa ttggattcca gtgataatgg cgttatgtac ttcacgcttt
    73921 gttagcacgc tgttgacact ttcagtacaa tccgccaaag tcaaatcaga aatatagtct
    73981 ttttgtaaaa acatgacaag ttgtgcgata tcttctacag ttacgccacg ttccttcaat
    74041 agttctcttg ccttttcttc taaagtctca gttttgacga ccatattatt gctccccctt
    74101 tattttttct ttctctattt catgttaacg gaacatgaaa aaaatgcaag aaactgcttt
    74161 cgggtttaac ttgaaatgca aagagatata aaaaatcaac taggacgaag atttttatcg
    74221 tataagcttg tgctgtgacc aggctgagtt cgttcctttg gattaatata gtgtaaagcg
    74281 ttgttcactg cagtaggtgc ttcaccgagc ccagtagcaa tcagtttcac ttttccttca
    74341 taggtacaga tgtcaccagc tgcataaacg cctggaatag aagtagacat atctgatttt
    74401 acagtaatgg catttctggt actatcaagt ccccaagaag aaagatgttc taaattagaa
    74461 gagaatccat aattgacgat cagagaatca atcatcaaat caatcgtctc gtcacttttc
    74521 acttttttta accggatatc tgtcagttcc ccattattgc ctgataatcc atcgatgaga
    74581 tagggagtaa gcaagttgac agatgaagat ttcaagcgtg atacactatg ttcgtgcgca
    74641 cgaaattccg ggcgacgatg aatcaagtaa acttcgcttg caataggctc taacatcaac
    74701 gtccaatcga tagcagaatc accacctcca gcaatagcga ctttttttcc agcatacttc
    74761 atcaaatcat tcacgaaata atccaatccg tggttttcaa atgattcagc attatctaaa
    74821 ttcaattttc ttggctggaa tgaaccattt cctaaagcta aaatgactgc tttggaataa
    74881 tggatgcctt tatttgtagt aatctcgata acttcgtctt cacgagtaag cgagagaact
    74941 tcttctttta aatggaatgt atggttaaaa gtagttaatt gtttttctaa ttgatcgatt
    75001 aattcacttg cttttattgc tggataccca ggaatatcgt aaatatattt ttcgggatac
    75061 aaagttgcta attgaccacc aagttgaggt agactgtcaa tgatttttgt tttagcttgg
    75121 cgcattcctg cgtaaaaagc ggcaaacatc cctacaggac ctgcaccgat gattgtaatg
    75181 tcatagattt ccataaaaat tcctcccttt tcacactata gcagaattta attgagaatg
    75241 cttctcaaaa atgtttgaat tcgaaatcga aacggtaagt tatagaatgt atctagtgat
    75301 gaaaaataaa agaaaacaaa tctagtattt ttacgagagg ttaggtatta tgttattatt
    75361 attatgaagt atgcaaatat taggaggaaa caatatggca ttcccacaac tagatttaaa
    75421 aagtgaaaaa ggaccaaaag ctgttatcaa aacaaaccgt ggtgacatta ctgttcaatt
    75481 attccctgaa ctagcaccga agacggttca aaatttcatt gaactttcca aaaaaggtta
    75541 ttatgatggc gtgatttttc accgcgttat tcctgatttc atgatccaag gcggcgatcc
    75601 aactggaaca ggaatgggtg gcgaaagtat ttatggcgaa agttttgaag atgaattcag
    75661 tcgtgaactg ttcaaccttc gcggagcttt atctatggca aattcaggtc caaacacaaa
    75721 cggaagccaa ttctttattg taaataacac aaatgtgcca gctaatatgc ttggacaact
    75781 agaaggtgct ggattcccat cagaaatcat tgaagcgtat aaaggtggcg gaactccttg
    75841 gctagatttc cgacatacag tctttggaca tgtactagaa gggatggaca cagtagatga
    75901 aatcgcaaat gtacaacgtg gtccacaaga ccgacctgta catgatgtag tgattgaaac
    75961 aattgaaatt tcagaatagt ttggtatggt acggagtaat tatgaaaaag gacgaaacct
    76021 agtaaggtct cgtcctttta ttttgaataa atgatttaat cgattgtctc taaagcatac
    76081 ttgattcgat taagtccttc cagtaaagtt tcttctggac aagcaatatt caagcgcata
    76141 tgcccatgac cggaaggacc aaacgtgatg ccaggattta atacgacttt tcctttccga
    76201 acaagagtgt tctccaattc ttggtcgtct gaaatatagg cggtaaaatc taaccacatt
    76261 aagtaagttc cttcagggtt cattattctc actttcggaa gatactgttc aaaaaactga
    76321 ttaactgttt gaacattttt ttctagataa ggaatcagtt ggcttaacca ttctccaccc
    76381 gtctcataag ccgcttgggt tccaatcagt ccaaaagtgt tgatttcgtg ctgttggttc
    76441 atcactaaat gtttttcaaa atcagctttc atctctggat ttttgataaa taccattgaa
    76501 tttttgattg cagctagatt gaaagtcttg gttgcggaag taaaagcaac tagtagatca
    76561 tctaaattag gatcaatcgt tagcatggaa gtaaatgtat gatcgaataa agttaaatct
    76621 tgatggatct cgtcactaaa cagaatcact tgatgtttta aacacaattc gcttaactgt
    76681 ttcaattctt ctttgctcca aacacgccct ccaggattgt gaggattgca taaaatcatt
    76741 gcttttacat tgttttcttc gatttttttc tccatgtcag acaagtccat gatgaaatga
    76801 ttattttttt ctagcaaaga gcttcgaacg atgtgacgtt gatttgtttc tataatagag
    76861 gaaaatggag gataaactgg gtcatgaatc aaaatagaat cgcctggttt tgtaaaagtt
    76921 tgtactgctg cagctaaact ggttaacaca ccacttgtaa aaacgatatt ttctttcgtc
    76981 aactccacag catggtgttg gcgttcccaa tgaatgatag cctgatatag tttatcagac
    77041 agagtggcat aaccaaagat tccatgtttg atgtattcac taaacgcttt agctacccca
    77101 ccgggagaca agaagtccat atctgctacc cacaaaggaa gtaagtcatc catttgatat
    77161 gtctcagcaa ttgcgtccca ttttacactt tctgtatctt ttcttgaaat ctgtttatca
    77221 aattcgatca tcttaagacc tccagtcatt ttcgtcgctt ctttttttga gctatttaca
    77281 gtataatgat aaatgcgaag agagggaagt agatgactta taaaattgga caaataattg
    77341 aaggaaaagt gacagggata cagccttatg gcgcattcgt ttctcttgat aacgagacgc
    77401 aaggacttat tcatgtttca gaagtacaat ccggttatac gaaaaatatc cattcattgt
    77461 taaaagtcgg acagccagta acagttcaga tcatcgacat tgatgaatat tccaaaaaaa
    77521 tcagtttatc tttaagaacg ttagaaaaaa caaatccagc tgttccatat cgcagaaaaa
    77581 ggtatttcac gaataaaaat cgtaagatcg gatttaccac tattgcggag cagttaccta
    77641 tttggataga agaagcatta tctgaactag aacggaaaga aaataagaaa taaaaagtgt
    77701 attttttctg aaaatgtgct agaattttta tgtaagccat agaacaagtt gatcgaggtg
    77761 gaaattttgg caagcaaaag agttgctggt acaattatgt tgcatttgga ggatggtact
    77821 aaaaaatttt tggtccattc aattgatgac aagttggaat ttgcgttagc ggaactttct
    77881 gaaggaaaga ctggtttagc gaatatactt aatttcttaa aagaaatagt tcatatcgat
    77941 gttagcaaga ttagtttgat ggaattgaca aatacacata ttaaagagga aaatgttccg
    78001 ttgtttgtct ttgaaactga acaaaagaat caaagagaag aattaggcga aggatatatt
    78061 tgggaagaac caggtcaaat gcgctctgtt cttggaactt acgaagtaga gggagtgcct
    78121 ttcttctaaa atacagatta agcgaacaaa gaagtttgaa tttttttcaa acttcttttt
    78181 ttattgtttg gtccaaaaaa tacaatgaaa tgttctgcta aagatagttt tttagtgcat
    78241 tttattttca aaatatgttg aaaacggttg tataacgaat aataataatt gatcgaaaaa
    78301 tcatttcaca aagtaatgct taatttatag ttgaccaagg aagaaataca tgataaattt
    78361 aacagcgttg attctgaagt ggatgttata tcacatttct aaaaaattta aaaaatagtt
    78421 attgacatgt tactaacgac atgataagat aactgagtcg tt
//
LOCUS       DAPBBR010000005        77295 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPBBR010000005 DAPBBR010000000
VERSION     DAPBBR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 77295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.005"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            598..1287
                     /locus_tag="RD488_000327"
     CDS             598..1287
                     /locus_tag="RD488_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7656429.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="RD488_000328"
     CDS             1274..2482
                     /locus_tag="RD488_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7656430.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="RD488_000329"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="RD488_000329"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDT7656431.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="RD488_000330"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="RD488_000330"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDT7656432.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="RD488_000331"
     CDS             complement(6585..7280)
                     /locus_tag="RD488_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HDT7656433.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="RD488_000332"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="RD488_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDT7656434.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="RD488_000333"
     CDS             complement(8479..8670)
                     /locus_tag="RD488_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDT7656435.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="RD488_000334"
     CDS             complement(8691..9581)
                     /locus_tag="RD488_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDT7656436.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="RD488_000335"
     CDS             complement(9568..10335)
                     /locus_tag="RD488_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7656437.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="RD488_000336"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="RD488_000336"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDT7656438.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="RD488_000337"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="RD488_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDT7656439.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="RD488_000338"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="RD488_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDT7656440.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="RD488_000339"
     CDS             14906..15289
                     /locus_tag="RD488_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656441.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="RD488_000340"
     CDS             complement(15457..16215)
                     /locus_tag="RD488_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HDT7656442.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="RD488_000341"
     CDS             complement(16233..17051)
                     /locus_tag="RD488_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7656443.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="RD488_000342"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="RD488_000342"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDT7656444.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="RD488_000343"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="RD488_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDT7656445.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="RD488_000344"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="RD488_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDT7656446.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="RD488_000345"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="RD488_000345"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDT7656447.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="RD488_000346"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="RD488_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDT7656448.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="RD488_000347"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="RD488_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDT7656449.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="RD488_000348"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="RD488_000348"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDT7656450.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="RD488_000349"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="RD488_000349"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDT7656451.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVKEQGSEE"
     gene            27093..27392
                     /locus_tag="RD488_000350"
     CDS             27093..27392
                     /locus_tag="RD488_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDT7656452.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="RD488_000351"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="RD488_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7656453.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="RD488_000352"
     CDS             27980..28216
                     /locus_tag="RD488_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDT7656454.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="RD488_000353"
     CDS             28359..30332
                     /locus_tag="RD488_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDT7656455.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="RD488_000354"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="RD488_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDT7656456.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="RD488_000355"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="RD488_000355"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDT7656457.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="RD488_000356"
     CDS             33211..34503
                     /locus_tag="RD488_000356"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDT7656458.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35239..36102
                     /locus_tag="RD488_000357"
     CDS             35239..36102
                     /locus_tag="RD488_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7656459.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36231..37853)
                     /locus_tag="RD488_000358"
     CDS             complement(36231..37853)
                     /locus_tag="RD488_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656460.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38102..38623
                     /locus_tag="RD488_000359"
     CDS             38102..38623
                     /locus_tag="RD488_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7656461.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="RD488_000360"
     CDS             complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="RD488_000360"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDT7656462.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40704..41522
                     /locus_tag="RD488_000361"
     CDS             40704..41522
                     /locus_tag="RD488_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDT7656463.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41625..41822)
                     /locus_tag="RD488_000362"
     CDS             complement(41625..41822)
                     /locus_tag="RD488_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656464.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41991..42569
                     /locus_tag="RD488_000363"
     CDS             41991..42569
                     /locus_tag="RD488_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7656465.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42664..42801
                     /locus_tag="RD488_000364"
     CDS             42664..42801
                     /locus_tag="RD488_000364"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656466.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43614..44117)
                     /locus_tag="RD488_000365"
     CDS             complement(43614..44117)
                     /locus_tag="RD488_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7656467.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44476..45501
                     /locus_tag="RD488_000366"
     CDS             44476..45501
                     /locus_tag="RD488_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7656468.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45848..46726
                     /locus_tag="RD488_000367"
     CDS             45848..46726
                     /locus_tag="RD488_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HDT7656469.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47202..47318
                     /locus_tag="RD488_000368"
     CDS             47202..47318
                     /locus_tag="RD488_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7656470.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48246..48584
                     /locus_tag="RD488_000369"
     CDS             48246..48584
                     /locus_tag="RD488_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656471.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48678..48908
                     /locus_tag="RD488_000370"
     CDS             48678..48908
                     /locus_tag="RD488_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656472.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49308..49679
                     /locus_tag="RD488_000371"
     CDS             49308..49679
                     /locus_tag="RD488_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDT7656473.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49953..50645)
                     /locus_tag="RD488_000372"
     CDS             complement(49953..50645)
                     /locus_tag="RD488_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7656474.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50648..51433)
                     /locus_tag="RD488_000373"
     CDS             complement(50648..51433)
                     /locus_tag="RD488_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7656475.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51670..53070
                     /gene="lacG"
                     /locus_tag="RD488_000374"
     CDS             51670..53070
                     /gene="lacG"
                     /locus_tag="RD488_000374"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDT7656476.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53095..53412
                     /locus_tag="RD488_000375"
     CDS             53095..53412
                     /locus_tag="RD488_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7656477.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53425..55098
                     /locus_tag="RD488_000376"
     CDS             53425..55098
                     /locus_tag="RD488_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HDT7656478.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55112..56743
                     /locus_tag="RD488_000377"
     CDS             55112..56743
                     /locus_tag="RD488_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HDT7656479.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57615..58805
                     /locus_tag="RD488_000378"
     CDS             57615..58805
                     /locus_tag="RD488_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HDT7656480.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58939..61128
                     /locus_tag="RD488_000379"
     CDS             58939..61128
                     /locus_tag="RD488_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7656481.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61125..62918
                     /locus_tag="RD488_000380"
     CDS             61125..62918
                     /locus_tag="RD488_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDT7656482.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            63118..63432
                     /locus_tag="RD488_000381"
     CDS             63118..63432
                     /locus_tag="RD488_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7656483.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63453..63830
                     /locus_tag="RD488_000382"
     CDS             63453..63830
                     /locus_tag="RD488_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7656484.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            63840..64613
                     /locus_tag="RD488_000383"
     CDS             63840..64613
                     /locus_tag="RD488_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656485.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64635..66038
                     /locus_tag="RD488_000384"
     CDS             64635..66038
                     /locus_tag="RD488_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7656486.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            66220..67404
                     /locus_tag="RD488_000385"
     CDS             66220..67404
                     /locus_tag="RD488_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7656487.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67401..67691
                     /locus_tag="RD488_000386"
     CDS             67401..67691
                     /locus_tag="RD488_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656488.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67688..67909
                     /locus_tag="RD488_000387"
     CDS             67688..67909
                     /locus_tag="RD488_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656489.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            67951..68730
                     /locus_tag="RD488_000388"
     CDS             67951..68730
                     /locus_tag="RD488_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HDT7656490.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            68797..69291
                     /locus_tag="RD488_000389"
     CDS             68797..69291
                     /locus_tag="RD488_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7656491.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            69347..69985
                     /locus_tag="RD488_000390"
     CDS             69347..69985
                     /locus_tag="RD488_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656492.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            70057..70452
                     /locus_tag="RD488_000391"
     CDS             70057..70452
                     /locus_tag="RD488_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7656493.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            70436..72889
                     /locus_tag="RD488_000392"
     CDS             70436..72889
                     /locus_tag="RD488_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7656494.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            72886..74913
                     /locus_tag="RD488_000393"
     CDS             72886..74913
                     /locus_tag="RD488_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656495.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            74910..75932
                     /locus_tag="RD488_000394"
     CDS             74910..75932
                     /locus_tag="RD488_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7656496.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            75949..76878
                     /locus_tag="RD488_000395"
     CDS             75949..76878
                     /locus_tag="RD488_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7656497.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            77123..77239
                     /locus_tag="RD488_000396"
     CDS             77123..77239
                     /locus_tag="RD488_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDT7656498.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT        24511 a        13813 c        15262 g        23709 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca caacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttaaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaacaaacgg tgttcaaaag cttgcatcta cggcactaag
    34681 cccaatcaga tgaaaaatat ggagtgctat ttttatctga ttgttcttac tgcttgatgc
    34741 agagcagctt tttcacaacc tctccactaa acggtgttct cctgccaact cctcggtcac
    34801 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    34861 agctaaacgg caggctcaca acctcttggt aaacggtgtt caatcagctg accctcggta
    34921 ttagctcaaa aaacggcaaa atatgaggaa ctattttttc cgtttttttc tctaatactc
    34981 aggtcaaaac gctgatttca caacctctga ttcacggtgt tccagaagta gcttctacgg
    35041 aaataagccg aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    35101 ttgaagctga ccacttctgt cacaacctct tattttgatt agaacttgcg aaaataaacc
    35161 ggttaaagtg tgtctagcgc aagagatttg ctataataga cgataagggt aaaatgtaac
    35221 gagaaggggt tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga tctgccatac
    35281 catgtattag caaaagaaaa agttgatttt ttatcaatga atctccaatt gaatgatcaa
    35341 gagttagtag atgacctcgg aaagacattc aattatgacc gctacatgaa tcagctgaaa
    35401 aatggtgcga tgcctacgac atcacaaatc aatgttggcc gatatttaga atttttccgt
    35461 tcttatgcgg aaaaacagat tcctgtttta tatgtggctt tttccagtgg attaagcggc
    35521 tcttacagta gtgcgcttca agcggttgaa ttgctgaagg aagaatatga agaccctgag
    35581 atctatgttt ttgatacaaa agctgcaagt attggggaag ggcttttagt attggaagct
    35641 gtaagattga aaaaagaagg taaaagcatc gaagaaaccc tagagtggct ggaaagtaat
    35701 tatttgaaag tccattcatg ggtaacagta gacgatctga aatatctaga acgaggcggt
    35761 aggatttcca aagcaagtgc tactcttggc agtctattga gtgtaaagcc tattattacg
    35821 gtggataaag aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa caagtcgatc
    35881 cagacaatcg tcaatgagac ggtaaaaaca atcgttgcac cacttgatca aatcgtttat
    35941 gtggcttacg ctggggatct agagagcgcg gagaaggcaa aacggctttt ggaagagcag
    36001 ataaagatga aagatgtgaa gctttatccc ttaggaccaa cgatcgccag tcacacaggc
    36061 tatggctgta tcgcgatttt ttcgatggga atcagtcgat aaaagcagta actcattctg
    36121 taaaaaagcc cagaaattga ttgtaacaaa aacagcgact cttaaaagat agatgagcat
    36181 cctatctctt agaggtcgct gtttttttat tttttaagct aaataggcca ttatgcccat
    36241 aactcgttca attgtttttg aatatctgca ttttccaaaa attcatcata tgtcgtatca
    36301 gctcgatcga tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa tgtttggata
    36361 aattgatggt catgtgacgc aaataagatt gagccagtaa atgccatcaa gccgtcattc
    36421 aatgctgtga ttgattctaa gtctaaatgg ttcgttggat catctaatac aagtacgtta
    36481 gctttcgaaa gcatcatttt tgaaagcatg caacggactt tctctccacc agataaaaca
    36541 ttcactggtt tcaatacttc ttcaccagaa aacaacattc ttcctaagaa gcttcttaag
    36601 aaggtgttat catcttcttc tttacttgca tattgacgca accagtctaa aatcgttaga
    36661 tcagtatcga attctttcgt tgtatccttt ggtaaataag aattacttgt tgtcacaccc
    36721 caacgtactg ttccagtatc tggcgtaatt tcacccatga taactttgaa tagcgttgtt
    36781 gttgttatat cattttctgc gacgaaagcg accttgtctt ctttgctcaa attaaaagat
    36841 atatcatcta aaattttctt tccatcaatc gttacactta cattttctac ctgcaataag
    36901 tcgtttccaa tctcacgttc aggtttgaat ccaacgaatg gataacgtct agaagaaggt
    36961 tggatatcgt ctaaagtaat tttttcaagc atttttttac gtgaagttgc ttgttttgat
    37021 tttgatgcat tcgcactaaa gcgggcaata aattcttgga gttctttgat ttgttcttct
    37081 tttttggcat ttgcgtttgc ttgaagttta gccgctagtt gactagattc caaccaaaaa
    37141 tcataatttc ctacataaag tttgatttta ccaaaatcta gatccgccat atgtgtacat
    37201 actttgttca aaaagtgacg gtcatgggat acaacgatca cagtattttc aaaattgatc
    37261 aaaaattctt ccagccaatt gatcgattgg atatccagac cgtttgttgg ttcgtctagc
    37321 aaaagaacat caggtttacc aaatagtgtt tgtgctaata acacttttac cttttgtcca
    37381 ccagttaatt cactcatttg ctgatggtgc aattcttcag ggatgttcag accttgcagt
    37441 aaaacagctg cttctggttc agcttcccat ccattaagct cagcaaattc tccttctaat
    37501 tcagctgctc gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat cgcatctttt
    37561 tctttcagca cttcatacag acgcttgtgt cccatgatga ctgtttcaag tacagtatag
    37621 tcttcatagt cgtaatggtt ctgtttcaat acggccatcc gttcatctgg tcccatagta
    37681 acggaacctg tggaaggctg cagatcccct gataacactt taaggaacgt tgatttacct
    37741 gcaccatttg caccaatcaa gccatagcag tttccggggg taaatttaat attcacatca
    37801 tcaaatagtt tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat caattttttt
    37861 cctcactttt atcattatta gttttgacaa gtcttataga attatatagg ggaaaggtaa
    37921 aagattcaag gcaatcgaac attctttgtg tttcacgtga aacagaatga aaaaaataaa
    37981 aataaaagcg gagcgaaaat agctactata ggatttatta gtttgcaaca gcataatttt
    38041 tgacgttatt tataagaggg agtactataa aactgtaaaa gaaatgaaag aaggattgaa
    38101 aatggatgaa aaaagaacca tcgactgggg ctcattgatt ttgggaattt tatttgtact
    38161 tgtctcattg ttatcatttc aagaccctgt cggaaattta gttgcaattg tagtagtctt
    38221 tgcgattttt gcctttatta aagggatatt tgaactgttt gtacggaaca gattaaaaga
    38281 gctaacagga tataaaggaa agatgccctt aataatcggg atcatcgata ttctagttgg
    38341 cgtctttttc ttattcaata ttggtgcagg agtcgcagca ttgccttttg tttttgcagt
    38401 atggtttatt gctgattcag ttttagcgtt atttactgct gacttggcaa gaggagtaag
    38461 tgaaggatat tattggttta cgatcatcgt caatatttta ggaattttat taggaatttt
    38521 cttattgttt aatccaattt cttctgcgtt gacattaagc tttttagttg gattctattt
    38581 tatgttattt ggtatcacac atatcgtcta tgcatttaga taagtaaaat caaacaaata
    38641 aaaaagccgg cttccgatta cagttttact gttgtaattg gaagccggct tttttatcat
    38701 ggacaaatat gcacgaggtg atttttaggt gtcgagacaa atttatgcaa aaatgtgaga
    38761 agctatatac acaaatttta tcttaatact cgaagcatag cgcagttgtc acaacctctt
    38821 ttcatataat tcattcaata ctggcaaatc atggacttca tatttttctt tgaatgcttg
    38881 gatttcttct tcagaatatt ttcttggatc taaatgcaga tcttctactg gcaatgggcg
    38941 cttgttattg atcttcacat cgattactac aggacgatct gattttgcag ctgcatcaaa
    39001 ggcaaatcga agttgcgagt attctgtgac tgtaaagcta tttgccccga gcgcttctcc
    39061 aactttaccg aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt ccgtatcttc
    39121 ttgttctgct tcgatgaaac caaaagaatc attcgaaaag acaacattaa taattggaag
    39181 ctgatatttg acttgtgtaa tgatatcttg catgaccata gcaaacccgc catcaccact
    39241 taaggtaaat acttgttttt ctgggtagct tagttgtgcg gcaattcctc ctggcacacc
    39301 attacccata gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt tcatattcaa
    39361 taaacgaata gaatggatag tcgtgttacc gacatctgtg acgaaaatcg catcgtcttc
    39421 agcaatacga ttgatttctt tatagacagc ctctggacga atcggttctt cctctcgatc
    39481 ttcaaaagat ttcaaccaat ttacccattt ttctttattt tcttgatttg ctaggtacca
    39541 gctatcagca gggcgagcat cccctaactc gacaagtctt tgcaaagctg tgtttgcatc
    39601 accgaggatc gacaaagatg tttcatggcg tcgtccaaat tttgacgcat cgatatcgat
    39661 ttggataaat tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt cgctaccgac
    39721 aaataagatc agatcggctt ctgccaatgc ttcatttccg ggtttagtag cgacacgtcc
    39781 agcaaaacca agaaagtttt cataatcatc aggaataatt ccttttgcta gaacggaagc
    39841 gacaacagga actgaaaaat gttctgagaa ttctttgatt tgcggaaatc cgtttcgcgt
    39901 tccttgacca acataaagaa ctggtttttt tgctttttca agataaggca aagcagctag
    39961 caaatctttt tcttctggta atatcacact tgttttgtga gtgtgagcgg tggagaaagg
    40021 ttgttcgtca atttcttcaa aaccaagatc aacagggata gtcacgatag ccacgccttt
    40081 atgctcatag gcggctttaa tggcttcatc tactacatgc ggaagacttt gtggtgtcat
    40141 gactgtacga ttgtatacgc taacatctgc gaaaatagga ttttcattta gttcctggaa
    40201 agagttatag ttcatggatg tagaagcaac ttgtcctaag aacgctacta gaggcacatg
    40261 gtccatctgt gcatcataca aaccattgat caaatgtgtc gcaccaggtc ctgcagagcc
    40321 gaagacagcg ccgactttcc ccgttaattt tgcatctgca gcggctgcga gtgcgccgac
    40381 ttcttcatga cgaacttgaa tgtagttgat ttcggttttt tcttgatata gcgcatccat
    40441 aattgaattg aaagatcctc cgggaatgcc gtaaatatgg tcgatacccc agctttcaag
    40501 aacttttacc attgcgattc ctgcattgat ttttgacatg gtgtttcact cctttagcaa
    40561 tgatgataca taaatttttt gtatctagag tatagaactt tttatcgaaa atcccaacta
    40621 attcgtcttt tcacaaaaat gtagtcatgt ttttgggaat atgctagagt agtacataga
    40681 tagattcaag agaggggaat ggcatggttg aatggctatt gagacttgaa ccttggcagc
    40741 aagcacttgc tgggacagct tttacttatt ttatgacagc tcttggtgcc gggttggttt
    40801 ttttctttaa agaaatcaaa aaagaagtgc taaacttgat gttaggattt gcttctggtg
    40861 tcatgattgc tgcaagtttt tggtctttgt tagatccggc tattacaaaa gcagaagaaa
    40921 atggagatat tgcttggcta gttgtaagta ttgggtttgg tttaggcggt gtgtttttat
    40981 atatggcaga taaaacactg ccccatatgc attttggacc acaacatgaa gcagaaggat
    41041 tgcctaccca tttaaaacgg acgatcttgc ttgttttttc tattacattg cataacattc
    41101 ctgaaggttt agccgtgggg gtagcattcg gtgcagcagc aactgcggat aatccgacag
    41161 ccgctatatt agccgctgtt tcggtggcgc taggtattgg tatccaaaac ttcccagaag
    41221 gagcagctgt atcaatcccg ttgcgacaag aaggtctgag tcgtaaaaag gcctttgttt
    41281 acggacaagc ttctggaatc gttgaaccaa ttgctggagt gattggagcg ctactagtaa
    41341 cgaaagtgga gctgctgctt ccttatgcac ttgcttttgc cgcaggagca atgatttatg
    41401 tcgtggtgga agaattgatc cctgaagcac agcagacatt gtccagcaaa cgtcattttg
    41461 cagtttttgg cgtcatgagt ggatttatca ttatgatgat tttggatgtg gcattaggat
    41521 aaataaaaaa aatatatatg atatatcaaa tagggccgcg aacttatatc gcgaccctat
    41581 ttttttagta agttatatca taatgaagtg aatggtatca tacattaata atagtttttt
    41641 ctatgtgtat ttcctttgat ccagcgaaca agccagatga taagtgcgat tgggattaga
    41701 actttgaccg caaaccataa aagcccgctt aggacactga caaaaagact gatgacgaag
    41761 ctagctgcaa ttagcactaa aagaaccatg aagatattta agaacatatt tttttgacgc
    41821 atacaaaacc ctcctcttgt tcattcttta ctatagaaaa agtataacag ggattgttta
    41881 aaaacacctc caactgaaga ctgattttta cttcatctac ttaaatgatc aaacaattgc
    41941 tttttctctg gtttatcatc taaaatagag cggaaaagga ggagaatatc atgcctaaaa
    42001 atcgtcttga agcatttaca gatgctgtaa tcgcgattat catgactatt ttagttttag
    42061 aacttcatga acctaacgga gacacgtggg aggcgctcgc tgcattaggt taccgatttt
    42121 ttatctatat tgtcagtttt atcattttag cgatttattg gaacaatcat catcatttat
    42181 ttcaagttgt acataagata aatggacggg tcttatgggc gaacagtttc tttgtttttg
    42241 cgctttcgct ttttccgttt gcaacttcat ggatcagtga gtacatcaat agcctggctc
    42301 cagaaatgac ttatggtttt gttaccttga ccgctaatat tgcgtattat atcttggcaa
    42361 aagaacttgt caaagcaaat aaaggccacg agaaagcatt gaaggcgatg ttgaataatt
    42421 acaagaaatc gtatctatcg attggtttga atgtgttagg aattgtctta gggtatttag
    42481 tagcgccagt agccgtgctg atcgcaaaca tcgtgattct agctgcttgg atcatcccaa
    42541 gtcgtaccat cgaatcacaa tatcggtaaa atgatccgtg tttaaaattt aagagaaaaa
    42601 tatagaaaaa ataaataaac gatcaaatat ccgagtgata ctagtattca aagagggatg
    42661 cagatggatc aaaaaagaat tcatgtagga ctgattacta gttttgtcac gatgcttatt
    42721 tatttggatc aaggtcattt gacttggaca gtagttggtg tcgtaggatt tttgacatta
    42781 ttcacagcaa taaaaaaata aacatcttta tgtaatctga tgttctatct atttaagaaa
    42841 agcatgttta cagcagtatg attctgttgt aaacgtgttt ttatttgtgg aaaatttaat
    42901 ttttagaaaa gtgtatcgaa aaatagatag ttagtttttc cacagtggat aacttcgtaa
    42961 gagataaaaa taaaaaatta gtcaaagaag ggcgtataga tttcttttga taggagatat
    43021 acaacagaaa tgaataaata ttaacgtgtt ttcaaacagt ataaaacggt gtggtttttg
    43081 gaataaaaaa ataacatatc tcattttacg cttttgttat tttatactta aaaaataacg
    43141 acacagaaaa taccgtgtct cagatttctc tactacttct aaaaactact gtttttttcc
    43201 tttgaaatgc cttcaaaaag taggatcagg cagaatatac tggcagaatc aaggagaagg
    43261 gagcctaaat aaggagaaaa accatagaaa atataaagta attacttata aaacaagctt
    43321 tttatagaaa aataatatac ctgagtaggg tataaattaa gacggaattc ctttctagat
    43381 tgagatattg actaggaaga atgttaagat tttaagcctt taagctaaaa aaaaaccctt
    43441 tttgttaaat aaggggaata tagcctgtca gtttcaaact gcaagtcgtc ctgctgcaat
    43501 aatatagtag attagagatg aaaatagatt tttttaaacc aatgactgaa taaaaagacc
    43561 gtcatagata cacattggaa tgtgtctatt acggtctttt tttacgaacg attttattga
    43621 agacggacag ttcgggtcaa aaataaaaaa gctacgatca gaaataagaa taaaatgtat
    43681 cccaaaataa tggctagacg gtctaactta tttgtcgata gatgtttgtt tagaagttga
    43741 taggcccata aacctatcag tcctcctgtt gtattagtta tcaaatcagt gatgtccgct
    43801 acgccaatac cgaataggaa ttgaatcaat tctgccaaga agcttacaag gaaaataatc
    43861 cctaattttt tagaaaaaga aagtctcttg aaattgacat tcaaaagcac cccaaaagga
    43921 aaaaagacaa tcaagttata agtggtctca cgtaataccg tcgtattttc aaaagaaaaa
    43981 gtagaaaaag ggacgagatt gacattgctg taagaataag tgagaaattg tggaagatta
    44041 aatgatagct tgaataaaat caaccataat agaaagaata aataaatccc taataaaaat
    44101 tttgatacat accgcataga catctcctcc atttaaaaag tataccatcg aaaaccgctg
    44161 aaaaatcata aaaaagtatg aagtttaagg accaacgtag ttatcgtacg aaaattagaa
    44221 gctttttttt gttgggaatc cggtttcttt aacaaagcta agatagcgag ttgcttggaa
    44281 aagttgctat cttttttctg tcaaaacgac tcggaatgtt cgttttttgt tctaatttct
    44341 ccaagttgtt tactttttga tactaagttt atgaaaaatc aagaaatagt tgttatacta
    44401 ggtaatgctg acaaacggga ttggcatttc atcttggttc agcttttttt ccaattacta
    44461 ggaaggaggg atagattgtt caagacttat tttcgtttca ataaaataca agataatcct
    44521 tttcgtatca tgaatctgat gctacttatc tttattgtat tatggttagg ttacataaat
    44581 catgattttt tgatttcaag tttttcatca ttagggatct ttactttttt ctattatcaa
    44641 aacataccga tgaaatattt gctgaaacgt atgtttctga tcggttgcgg actgttggtt
    44701 gctttcgttt tggggatctt atcgacttat gttttatggc ttgaaccatt tgccgtagct
    44761 ttggttgctt tttccagcag attcgtgttg cgattattcc atatttctaa accaggtggc
    44821 ttgttttttg cgatgctttc tgccatggga acgagcatgc agctgccaat cgctcaatta
    44881 ccgatcgtct cactttattt ttttatgggt gtcgtttttg ccctgattgc ggcagtgatt
    44941 acaaaattac tggattcacg gcctgagcag acaattgaaa aagcaacttt aaaagaaaga
    45001 tttcacgaag agcctttagt gatcattgat tctgttttct acagcgctgc cttatttctt
    45061 tccgtttatg tcagtcacgg cttgaatctg cataatcctt attggttgac cttgtcatgt
    45121 gcatcgattt tgctagcaga aaacttggat gcgatgaagc atcgacaagt ccaatatctg
    45181 attggatcga tgggtgggtt atgtgtgtcg gcattcttgt catttgtgcc gtttacgcag
    45241 ttgcagacca tttttctgat cacttttcta tatggaatcg cacaatttct agttgctaga
    45301 aattatgcag ttgctaatat ttttcttaat ccgatggcgt tgatgctatc tacacttatt
    45361 cgtggagcat acttgatttc tttgatcgaa tatcgttttt tagggatcgt cataggaagt
    45421 ttcatcggtt taggtgttgc gtgggtaatg acggttggtt tgcaacatta tttaacggtt
    45481 gttcgtcaaa aattagaata gaaggacaaa tatatgtgcc aaaagaggtt atgacaagat
    45541 ttttgtcaca acctctaatt caaggtgttc aaaagccaga ttctcagcat taagtcaaat
    45601 tcacacaaaa atgtggaaag gaactttcaa aaaaatttta tatttattct atcaaaaaat
    45661 tttatattta ttctatcaaa aaattttgtt tatgatggta actgaataaa ctttcctgag
    45721 atggtcaatg ctttccttga aagtcttaca gatattcttt cttcatagaa agtttaagtt
    45781 ttatagttag tgtacaataa aagtatgttt ataccatatg gtgtccggat aatcagtcat
    45841 ttaaacaatg aggttcaaag atatgaaaag gggaaatttg atgaagaaaa taagcaatga
    45901 aatccaaatt ctggcagaaa ctttaactct tcccaaagtc gttatagagc aaatgattgt
    45961 acaagcaaaa aacatccttg atgaggtgtt tgagcaatat agtcatgaac taatggatcc
    46021 taataaagca aaggcgactg caaagaaaat agacaaagtc tatgaagagg aaccttttgc
    46081 agcattagct atttatctat atgcagcttc tcaaagttgg aaaaaaattt atcaaccatt
    46141 gaagattcca agaactatct atttggcaac aatgaatgct tttactagat ttattcatga
    46201 acatttccaa gtaacaggaa gctatcgctt tgaccgtggt ttttggattt ggcattacac
    46261 tagtggcttg atctttcgga ttggtgaatt ggagtacgaa atgacatatt ttccgaaagg
    46321 gtacacggat ctaagattag aaggaaagca gtgcctttct cttcatattc cttccgatgc
    46381 agatttatct cagaataaga taagagatag ttacgaaagt gccattcgtt tttttgaact
    46441 ttattttcct gattaccatt accaagtgat gtacacagat acttggttac tatcacccaa
    46501 tcttactaaa tggttgaaaa aagagtcaaa aatctgtctt tttgcagccg attatcgatt
    46561 attatcagtt gatgaacagg acgatagtgg agtcccttgg atctttggac gagtagatgc
    46621 ccaaatacat gattatccag aaagtacgag tttacagcga caagcaaaag agcaattgct
    46681 tgcaggcgag cacattggct ctggcttagg tattcttact tcataagttt agtacttcga
    46741 aatagtttaa aagagcgtga gacaaaagta aagaacactt ttgtctcacg ctctaaacac
    46801 gtataaacgg cggaagcaga agcaactcct tcggaaataa gctgaaattc acaaaaattt
    46861 gaaaagcaat tttcgtgaat ttcttcttat ttcttggagt taaacgcttc tgtcccagcc
    46921 tcttttttag tgttctatcg aacacacagt acgttcaata ggtaaactag ctataacaat
    46981 agatattaaa gttaacggac aagagggcct tttttaggta gctaaaacgt aataatgaaa
    47041 atttatttcc agagatagga gtcaatcagc tagtctgatc gactgtttta acaagttgac
    47101 tttcatttta acttttgata ccatttaaaa cacaaatcgt aattgtttcg atttgtgttt
    47161 tttagcatga ctacaatcaa agaagaaagt gggtcgtcca tatggaaaaa acagatatct
    47221 caagtgcata ccgccgcttg aaaagcccaa atatcaaaac acgaaaacgt gcgctgaaga
    47281 tcatcaaaga tgtgaaacgg aatagtggga aaaggtaaga agaaggaaac ttaattaaaa
    47341 aaatagccga aaaacgtttt tcggctattt tcaataatcg gtttttgtgt aaggtttccg
    47401 aaagaactgc tgttgatttt ccatttttaa catatgataa attggtagaa tctttctttt
    47461 caaattgata ccattcccta attccagtta tatagttaac tacagaacca caaagcacgt
    47521 acgtttataa aagtattatc tgtagttatt tttcaattcc ctttcaacct cttattttga
    47581 ccagtagtat tgatcacttt accttttaac acctttgttc gtttttgaaa catttttagt
    47641 caagaatgga aacgtaacta cataatcaaa ggttttgcga aatatttcat gaaatatttc
    47701 atgtagaagc gagcaatacg gttgcaaata accattatcg tttaataagc agttacgaaa
    47761 gctcccaata tctctaacgt tcagctcact ccatttcttt tcttcaaaaa aatcagtgat
    47821 tcgtatctct ttctatttgt cgaaaaagtt aactttaaaa agtaacgccg aaaaaatatg
    47881 caaaaaaata aaaaagcagt tactattgct agaataacat caaggaataa taagttttgg
    47941 ttttcagata atagtcgata agttgtgtat tggaatttta gatacagtaa taaagtattt
    48001 ttcatgaaat tttgtgagaa tcactattac aagtatcttt aataaaatta atggttaagg
    48061 aggaacttaa agtagaatgt aaatgaatag ttgtagtcag tcgattgtga tactagactc
    48121 aaagttgcag gaataagttt ttcaatttgt gattggaaga taaaaaatga aaaagaaggg
    48181 ctttttttta tactttgttg attgtagtgt ttattttccc tctgtttagc caagtaacat
    48241 tttctatgac tcaaccagtt tcaagtgagg aacatgataa cctttttcgt gctacagaag
    48301 agtttaagaa atatcaggaa aatattgttc cggagactcc attagctagt gagccaatta
    48361 ctgatattga tggaaaccaa ataggatggt atatacagta cgaagttatg gtggtaaata
    48421 atgactcaat agtaaaaaat acagtaggct tagagctaac accgattgaa aaggtgagtt
    48481 cattgttaac gtatatttat actgatgaaa gtgacgagac tgagatcatt ttaacggatt
    48541 actcaaaaat tgctactgat aaaaagtata tattgtggat gtagacacta gtgaaatact
    48601 ttatgatata gaaattgatg aaaatttact agatgtagca caagaaatcg atcatcaaaa
    48661 gcaggaagct attcgatatg ctggtagaaa agggaaaaga aaatatttat tacgtgaatg
    48721 tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt caagagtcgc tactcaatta
    48781 actcgactcc gacatttaca gtttacagag aaggatcgat agaaaaaact gttttttgga
    48841 ctaaagaaag tggaatgtct ttagctgaag tagaagagtt tttggattat gttagtatgc
    48901 aacagtaagg gagttcttat tatgaaaaat tttgacacat attatgttat tgttttttcg
    48961 atatctttgc tgttaatatt actaacttta atgcagtata aagagtatcc agagtatttt
    49021 attttaactt ttgtatattt agtaagtagc tacacacttc tatataaatt cagaagttct
    49081 tctagagttt ctaaagtttg tttcttaatt agcttattga ttctataata tttttgattt
    49141 atataggaaa ttaaaaatat tatagaatca acactcagag aacgggttgg tttttaatag
    49201 atttaataag tactgataat gaaatttctc ctggttggga aaacgaagtt ggttaccctg
    49261 tagaagaatt ttttcaagat tactttgcgg agtatgccga taggataatg agagattacg
    49321 taacagataa aactcaagaa gtcatcaatc aatcccagtc attaaatgaa ttatctgata
    49381 aggcgaaaga agaagcagtt gccattattt cttcagggat tagtgactat attgatatga
    49441 gtggtgaaat caattatggc gataaagaca aaattgtacg catgataaaa gcttttatca
    49501 aaacttttga tgtgaaggca gatcttaagt ttaatgatac ttacctagta ggaaaattaa
    49561 ttaatatcct tgggacagag aaagatacgg aaacgtttat ttcctctttg tctatgttgt
    49621 ttacagataa gcatttttca actcagcttg gtggagagga actagtggaa atcttttaac
    49681 cattacgccc agcattaata aaagtatatc aaaaaagtac tcctgatgat ttttaagatt
    49741 ggtttgagaa ataatgtgaa aacactattt ttaatgttaa ttatagatag agatgaacgc
    49801 gtcatatggt taaaagaatg aaaaagtcaa agatacactg ctatatttca ctaaggatat
    49861 agcagtgtat ctttcatgtc gtttcactgg cagtttttta taaaaggagg tgtgcatttc
    49921 agttgctttt ctttggtagt tagttgaatc gtttaagaat taacggatgt ggcagacagg
    49981 tgctctgtcc aaaaaccagt aaaatctttg atggttccat ctttatttag ctgtgcctgt
    50041 tcaaatactg ttttgttttt accgaatgga tcaattgcaa taattgttcc gatccccgca
    50101 cgtttggcag caagtaatcc tgagtaagca tcttcgataa caagacaatc agccggagct
    50161 aagctcagtt tgtctgccgc tttaagaaaa atatccggtt gcggtttccc agggaaagag
    50221 ccgtcgtcat agacaatctt gtcccagtca aaccagcggg ctaaatcgaa aatatcaaaa
    50281 taaaaagcaa cattctcttt gacagtagcc gtggcaatcg ttaatggaat ctgttggtca
    50341 gtcagctggt caagagtcgc ttcaagccct tttgtcaact gaagctcgtt ttcattttgc
    50401 aagcaaagca tacgataata gctttctttt tcttctgaca atacggcgat ctcagaggcg
    50461 gtcaaatgct ctgaaatgaa atgtttcaaa atctccgtat tcgtccgacc atgaatattt
    50521 tttaaaatat cctcgtctga taaaccatct tttgtatgat catgtatcat atgcagccaa
    50581 gcagcttcat gcagatgaga gtccaaaaac attgttccgt tgaaatcaaa tataatccct
    50641 ttcatagtta cgctcctata gtggtatttt cggttgaatc agcaatttgc agatcgacat
    50701 attgtgcata gtgctcttga acctcccgcg agatctggcg atccgtaatg agcagatcga
    50761 aatcatgcaa attataaaac acataaaaat catctcgatt gaatttttta ttatcaacga
    50821 gtagatattt cttacgggaa ttatttagag cgatctgctg tgcttctcct tcttcggtac
    50881 tgtaagtaga gatcgcttcg ttgtgaacgc catttgaact gataaatgct tttgtaaact
    50941 ttagtcttct taaattgtcg ttggtgatcg gtccgacaaa tgcgccggta tttttccgga
    51001 aatcaccgcc aatcagtaga atttctggtc catctgcttg agcaagaata tcaaaaactg
    51061 gataattatt tgtaatgatc cgaattttct tgttcagtaa atgcgtcgcc aatagttcga
    51121 ttgttgtacc tggtcctaag aaaatcgttt ctccctcgtg aatcaaggag gctgctgtgg
    51181 cagcaatttc ttttttttct tgaatctgca gagtggcttt ttcagtgtga gaaagttctt
    51241 gatctaaagt gtaggaaaga ctttgagccc ctccatggac acgcagcagc ttgcccgatt
    51301 tttctaattc atctaaatct ctgcgaacgg tcatatcaga aacatctaat tgattgatga
    51361 tttcattaac ggtaaggatt ccttttttat tgaccatttc tacgatagta agcaatcttt
    51421 cttttttcaa cattgtcttc acctctaatt taaggataat ctatcatata aacggacaac
    51481 agtcaatcta attcgaacaa aagtaaacat ttagggtggt ttttatgttt gttacaatag
    51541 attttattgc tgttttctgg tttttatgat tatttgtgtt tgtttttgtt gacaaatgtt
    51601 ttggatgcgt ttacaatgca atcagttaga aagagcgaaa actgattata gatttgagga
    51661 gagatgtaca tgcttaaatt accagaagat tttatttttg gcggagccac agcagcctat
    51721 caggttgaag gagccactaa ggaaggtggc aaaggcgctg ttgcttggga tgacttttta
    51781 gaggaacaag ggcgattcag tcccgatccg gcaagtgatt tttatcatca atatgcaaag
    51841 gacattgaat tgtgtgaacg ttttggtgta aatggtctaa gattatccat tgcttggagc
    51901 cgcatttttc ctgatggagc tgggaaacca aatccagaag gaatcgcttt ttatcatcgt
    51961 gtgttcgaag aatgtaagaa aagaaacgta acgccgtttg tgacgttgca tcattttgat
    52021 acccctaaac gtttgtttga ccatggagat tttttgaatc gagaaacaat agaagcattt
    52081 gtttcctatg ccattttttg ttttcatgaa ttcaaagaag tcaaggtgtg gagtaccttt
    52141 aatgaaatct atccagttgc aaccaatcaa tatttgttag gtgttttccc accaggaatc
    52201 aaatatgatt ttacaaagat cgtcgcctgt cttcataata tgatggttgc tcatgcccgt
    52261 gtagtgaact atttcaaaga aaacgaactt ccgggtgaaa ttggtgtagt tcactcatta
    52321 gagacgaaat atgcggcaac agacgcgccg gaagataagc atgctgcctt tttagacgat
    52381 gcattgtcga tccgtttctt attagatgct acctatttag gctattattc aactgaaacc
    52441 ttgactgctc ttgatgagat atgtgaagca aatcaggcca gctatcattt tcctgaagaa
    52501 gatttcgttg aattgaaaaa agcatccacg cgtaatgact acttagggat caatcactac
    52561 caatgccatt ttgtcaaagc ttacgatgga gaaaatgcaa tccatcataa cggtacgggt
    52621 gaaaaaggga cctctgttta taaagtgaag ggaatcggag aacgtattta taaagaagga
    52681 attcctcgaa ctgattggga ctggctgatt tatccagaag gtctatatga cttgttgctg
    52741 cgaattaaaa gcgattaccc acattacaac aaaatctata tcactgagaa cgggatgggg
    52801 tataaagatc agtttgaaga tggcattatt atggatcagc cgagaatcga ctatttgaga
    52861 gtctatttgg aatccttaag caaggcgata acagccgggg taaatgtgaa ggggtatttt
    52921 ttgtggtcgc ttatggatct tttctcatgg acaaatgggt ataacaaaag gtatggcttg
    52981 ttttatgttg attttgaaac ccagaagcgt tacccaaaag aatcagctta ctggtacaag
    53041 ttggtcagtg aaaccaaaac gattatttaa taagtgataa tggaggaaga aaagatgaat
    53101 aaagaggaat tacaaatgct tggttttgag atcgttgcat attcaggcga cgctcgcagt
    53161 acattattga aattattgaa agaagtaaga caaggaaact ttgaacatgt tgattcggcg
    53221 ttgaaagaag ccgacgaaaa tttaaccctt gcacataatt cgcaaacaaa aattttagcg
    53281 gaagaagcat ctgggaaaga gatggagatg ggattcattt ttatccatgg gcaggatcat
    53341 ttaatgacca ctttattgct gagagatctg attcaagact ttattgtact gtacagacag
    53401 aatcaaggat aggagaagaa cgctatggat ggaatcatta aacaaatcga aaaagggaaa
    53461 ccattttttg aaaaaatctc acgtaatagt tatttaggag ccgttcgtga cggattttta
    53521 acagcgatgc cagctatttt attttcaagc attttcattt tgattgctgc ggttcctgag
    53581 atttttggtt accaatggcc tgaatctgtc tccacatggc tatggaaagt ctataattat
    53641 tcgatgggtg ttgtagggtt actcgtttca gcaaccactg ctcgctgctt ggctgattcg
    53701 atgaatcgtc gcttaccgaa aaacaaagta atcaacacca cctctgtgat gctggcctct
    53761 gtggtaagtt tcctgttgtt aagcgtctct ccgattgaag gtggattttc aacggaatat
    53821 atggggacaa agggactact ggcttccttt gtcgctgcat ttttaacagt taatttatat
    53881 aagttttgtg tgctgaaaga tattaccatt aaaatgccta aagaagttcc tggaacgatt
    53941 tcgcaaacct tccgagatat ttttcctttc tctttttcag tatttgcggc cgttttaatt
    54001 gatttaggca ttcgacaaat cttccaaatc tcatttgcag aagcaatcat tacggtgctg
    54061 cagccgctat ttacagcagc tgacgggtac ttaggaatcg ctattatctg gggagcgatg
    54121 gcgctgtttt ggtttgtcgg tgttcatgga ccgtcgatcg tggagccggc aattgcggca
    54181 attatctatg ccaatgtgga aaccaatctg caattgttca attccggtga acaagcttct
    54241 aaagtactga cggtgggttt agggaatttt gtaggaacta tgggaggaac tggggcaaca
    54301 ttggttgttc cttttatctt cctactcttt gctaagtcta agcagttgaa ggcagttggg
    54361 aaagcttcct ttattccagt aagtttcgct gtcaacgaac cattgctatt tgcggcaccc
    54421 atgattttga acccttattt ttttattcca tttttgttaa cacctgttgt aaacgtttgc
    54481 ctgttcaagt tttttgtcga tgtattgggc atgaacagct ttatgtacgt tttgccttgg
    54541 gcaactccag caccgatcgg tttggttcta ggaacgggca tgggtatctt agcttttgtt
    54601 ctagcagcgg ttctaatcgt cgttgacttc ctgatctatc taccattttg caaagcatac
    54661 gatgctgtct tagtagagaa agaagcacaa aaagcagagg tgatcgcaac cgaggaaggt
    54721 gcttctgccg atgtacgtga ggaagtacct gtggcagcga gtcaagttat cagcgatgca
    54781 aataaagaaa tcaatgtgtt ggtactttgt gctggcgcag ggacaagtgc gatgttagct
    54841 aatgctttaa aaaaaggtgc atctgaatcg aaagcaccga tcagtgcaat ggcgggtgct
    54901 tatggttctc attacgaaat gctgcaggat tttgatatgg tggtcttagc accgcaagtc
    54961 aattcttact atgatgatat caaagaagac accgatcgct taggaatcaa gctggttgcg
    55021 acaaaaggag cagaatatat cggattaacg agagatcctg aaaaagctgt tcagtttatt
    55081 ctgaaccaat ttcaataaag gaggagccat aatgaaaatg ggaatttggt tgcgtaaagc
    55141 tgttttattt gcagctgtgt taggggcttt gggggctgtt tcaaaaactg ttgaagcatc
    55201 tgccagcgaa tttattcgcg gagcagatat ttcgatcctg tcagatatgg aaaaatctgg
    55261 tgcaaaatat tatgaagacg atatttcaaa agatgcctta gagattttaa aaaataatgg
    55321 tgtcaactat gttcgactgc gtttgtggca ggatccttat aatagtaatg gagaaagtta
    55381 tggagcaggg acaaatgatc tggaaacgac gattgacctt gcaaaacgag caaaaaatct
    55441 gggacttaag gtgctgctgg attttcacta cagtgatttt tgggttgatc ctgggaaaca
    55501 gaatcttcct aaagcatggc aaggtctgac ctttgaagaa atgaatacgg cattgtacga
    55561 ctatacaaag aacgttctgt cggaaatgaa gcagctggac gtttatcctg atatggttca
    55621 gatcggcaat gaactgaata gcggaatgct ctggccttat ggcaagtctt ggggagaagg
    55681 cgggggagaa tttgatcgat tggctgcttt tttgaagtct ggtatccaag ctgttcgaga
    55741 cactcaacct aaaacaactc cagtaatgct ccacttagct gatggtggcg atacaggagc
    55801 atttacttgg tggtttgatg aaatcacgag tcgaggtgtg tcatttgatt taattggagt
    55861 gtcgtattat ccgtattggc acggttcaat gaatgaactt caaaccaata tgaatgcgat
    55921 cagccaacgg tatggtaaag aagtgatcgt agttgaaaca gcttatgggc atacaacagc
    55981 gaatgccgat actatgccaa atgcttttgg tgaagccgaa gcagctgcgg ggggatatga
    56041 accaacaccg acaggacaag cagagtattt gctggatctt gccgatcgga ttcaggcagt
    56101 accgaataat cgcggggcgg gcttcttcta ttgggaacct ctttggtaca acggaaatgt
    56161 gagttgggca acacaagcag gtatgaatta tctcagtgtt caatccacta tgggaaacga
    56221 atgggacaac caagcgatgt ttgattttgc tggaaacgcc ttgccaagct tgcgtgcgtt
    56281 taaacaagca ggggcgcaaa taaatctagt taaaaatgca agtttcgaaa gcgatggacc
    56341 aacgaccagt ccttccaatt ggcaaacctg gtttcaacaa ggaaccgcta agggtacgat
    56401 caaaacggaa gcgggcactt tttttgggga ctacaaacta actttttggc aggatcaagc
    56461 atacgaggca tcagcttatc aaaatgttag tggcataagc aaaggaactt acacattgag
    56521 tgcctatgta atgtctgggg gagagtttga tactaatcag ttatatatca aaaattatgg
    56581 tggagcggaa ctaaatactg cggttgttaa aacaagtgaa tggacaaaaa ttacaatcaa
    56641 agacattcca attacaacag gtgtttgtga aattggggtt tatagcaagg cttcaggaaa
    56701 tgcttggacg aacgttgatt ttgtttcatt ggtgaaacaa tagactgcgg atcgtttcga
    56761 ttcaagatcg gaggttccct tcagccacat cgttagcgta gaaggcagga atcgaacctg
    56821 cacctcgcct ttgccaaaaa taaccagaaa cgatttccag tcatttttac caaaacgagt
    56881 aaagcaccag acttcatcta cactttgtat tatgctaaag agagttcaac gatttcgtaa
    56941 gaagcaatga aaaaattgca aaaagttgtg cagataacat aaagtttgtt taagaaaggg
    57001 taaccttaga attccgtcgt gaatatgatt tgagcactta gatggataga aaaaagttct
    57061 cggaaaacag ttcgtttttc gagaacttct ttttatgata agaatgaaac aaattaactt
    57121 atattatagt ctcttttggt agggaaccat cttattttta atgaaaatca agcattttag
    57181 ctattgaaga atgttgattt atagggattc cccctccata ttatgttggc tctttattcc
    57241 cactctgttt tcaacgtaaa gtgtataaaa cagaatgcga tactatcaag ggagttaaaa
    57301 caatatacag aacagtaaaa cactataaat aaaaataaaa gtgcaataaa agtgcaattt
    57361 ttgcacctaa tcatactctg tttatatatg aaaactagat tctgaatcca atatttggtt
    57421 aacgagaggc gttcgaattt gaacgtcttt tatatattac tttcaaataa atatgaggta
    57481 gaatactatc tattttcttt ttaacccaat tgttataatg gagagtgtaa aatattttgt
    57541 gtaaatagaa aaaaggaagt cccttctgta gaatagagtt accacaacac attcacagaa
    57601 gagaggactt ccctatgaac gattttacta cagaaattct aaagactcta gcgaacaaag
    57661 gcgatttgaa tgaattattc cgtgtccatt tggagaaagc agtcaatacg cttctcaaaa
    57721 cggagttaac ggctttccta gattacgaaa agtatgatcg cattggtttt aacacgggta
    57781 attctcgtaa cggctcctat gaccgtacgg tcaagaccga gtatggggaa cttcatctcc
    57841 agattccgcg cgaccgcaat ggtgagttca agcaacagac tgttcctgct tatagacgga
    57901 cgaatgacac gttagaggag accgtcattc acctcttccg aaaaggtatt accatgtcgg
    57961 aaatcgcaga cttgattgag aaaatgtatg ggcattacta cacgccccaa accatgtcca
    58021 atataacaaa atcatttaca gaagaggtaa cggcgtttaa tgggcgggag cttcatgacc
    58081 gttatgctgc tatttatatg gacgcaacgt atattccgtt aaagcggaaa accgtcgcca
    58141 aggaagctat tcatatcgca gttggcattc gcccggacgg atcaaaggaa gtattgagct
    58201 atgcgattgc accgactgaa tccatcacga tttgggagga aattttattg gaccttcaag
    58261 agcgcggttt gaaaaatgtc ctcctgttca tcacggatgg cttaaagggg atggtaggag
    58321 cgattagtcg gttctatccc aaagctcgtt ttcaacattg ttgtgtacac gtttcccgta
    58381 atatcagtca taaagtgcgt gtcgatgatc gtaaggaagt ctgtgatgat tttaaaatgg
    58441 tgtatcaagc ctcatctaaa gaggtggcgt tggaagcacg tggtactttt gcggaaaaat
    58501 ggaaaaccag ctatccaaaa gtggttgaat cgattctttc gaacgatcac ttgctcactt
    58561 tctatgattt ccccttggcc atacgcaaga gtatttattc tacgaacttg attgaatcct
    58621 ttaataaaca aatcaagaaa tacagccacc gcaaggaaca gttccaaaat gaagagtcga
    58681 tggaacgttt cttagtctcg tcttttgata cttacaacca aaaattccta ggtcgcagtc
    58741 ataaaggttt ccaacaggcc gaaggcgagc tcgaacaaat gctaagccaa ctgattgaga
    58801 attagaaaca atctgcagta gggaagaatc atttacacaa aattattgac gctcccttat
    58861 aatgagaact tttactaaca taatttatga taaacttact atataatcat attaattaaa
    58921 tagttaggag atctgcttat gtttatatct actcttcaaa ttcgaaattt tagaaattat
    58981 gaatccgaaa tctttcgatt cgataatgag acaaatacta ttataggtga gaatgattca
    59041 gggaaaacca atgctcttac tgcattgaga atcttattag atgatagtta ttactatagt
    59101 agtaaaacac taaaagaatc agattttttt catggaattc aaaatgggtg gcaagggcat
    59161 tggattatta tctctgcgac atttgaagga atcagcgaag aagaatttga caatgagatt
    59221 tgtgcttcca tttctttaaa ttctgaaagt caaacaatct tagaagaatt gatttcaaat
    59281 gcagataaag gtgtaggtag tatttctcta tttattagac ctaacaaagc tattagaaag
    59341 caattatttg atatttccac tgaattagac tctcatcaat ttaacgaatt tagaaattct
    59401 attcgtctat ccgactatga attttactac acatctaaat caaatctaaa tttctgtatc
    59461 aatgaaaatt atgataaatt ggtaggaaga ctcaatgaca atatagctag taatcctgaa
    59521 gaagacgatg aagctctgtt gggctcaaga attgacatgt cagatatttt caagcatatt
    59581 tcggttgttt atgttgacgc tcttcgagat gttcttagag aaatgaaaaa caatcgaaac
    59641 ccagtcaaaa gaatcatgga aacaattgaa tcaaaaatat catcagataa tgttgagtca
    59701 ttaaaaacaa ttatacagca attaaatgag actattacca gtgttcctga aattaggaaa
    59761 attggcgaaa atattaatcg gcaactaaat agcataattg gttcagtgta ttctcctaat
    59821 cttcttcttt cctcaactat gtcagatgat atgggttctt tagcaaaatt tctttcaatg
    59881 aagccagaac aaaatatcga cttagactta ctagggttag gacatctaaa tatgatttat
    59941 ttagctttga aaatagtcga atttgaagcg tgtcgttcaa gagaactact taatattatg
    60001 ttgattgaag aaccagaagc tcatattcat catcatattc aaaaaactct gttcgaagga
    60061 ttaaatcttc aaaaaaacta tactcagatt ctcatgacca cacattctgt acatttagct
    60121 gaagtgtctg aaatatctcg gatgaatgta ttaaaatcgt ttaatggcaa atctatcgtt
    60181 atgaatccag caaataatct gaactcattt gctaaagaaa agttaaaaaa gaacaatcta
    60241 aatctaataa acgcagtaga gagatattta gatgttaaaa gaaatggatt gcttttttct
    60301 aaaggtgtta tcttagttga aggagatgct gaagaaatac ttattcctca aatagtaaaa
    60361 aaattatttg gtataaactt agacgaactt ggaataggtt tgattaatgt tggtagtact
    60421 tcgtttgaat atatcgctag cttgtttgac gatgatagaa tacagagaaa gtgtgctatt
    60481 gtaactgatt tagatgaaca ggcaatccca tcagaacatc gattgtataa aagcactgca
    60541 caagagaaag gtcaagcaag aaaagaaaaa ttatcctccc tttttaatga aaacaattgg
    60601 gttaattgtt tttatgctaa tacaacattt gaaattgagt ttttagatgt gaataaagaa
    60661 aatattctaa cttatgtcag tccaattata gatgacgcat tcaaagataa aaaaacaata
    60721 actgcttata aagaagaaat acaaagtgaa caatatttag aaagaaattt agcgatgtta
    60781 aaactagcca atcatgttgg taaggggtgg tttgcaattg agttaggtga aaaaattgac
    60841 tttttaatca aaattcctaa gtatattctt aatgctattg cttttgcatg tcaggaaata
    60901 gtagatctct caatttataa aaaaattcta ctccatacaa tcgacttgta cgaggaaact
    60961 acagaattgt cagctttatc agctagttta aaaacaagtg atacagctga tttgaatata
    61021 gcaataattt ctttattaga gtactttggt aaagatgagg atgttgtgta tctaatcaat
    61081 cagatagaaa attacacaaa aatactttat gctgaggttt caaaatgaca aatatcttcg
    61141 aaaaaatcgt aaatgattta aatttagaac aaaaagatgt tgtggaaagt gaagataacc
    61201 tttatgtaaa tgcatgtcct gggagtggga aaacaagggt acttacaagg aaaattgctt
    61261 accaagcaat taaacacgat ggatcactaa aaagaataat tgctatcaca tacactaata
    61321 gagctgctga agaaattaag gaacgcctaa gtttacttag tatagatgat gatattaata
    61381 tttgggtggg gacaatacat cagttttgtc ttgaatttat tatttatcct tttaaaatga
    61441 atctctcaag agtatcaaaa ggatttacaa ttattgatga ttatactcaa agagcttacg
    61501 tcagccaaat taataatatg ctgaatttaa atctcaaaac gtatgaactg aacaaaattg
    61561 atttgtcact ttctcatgat tttaaaatta atgaagttca gtatactcaa gtttctgaaa
    61621 tgtatcacac tatgttggaa aaaaataaag aaattgattt tgatatgatt ttactagtag
    61681 cgtataaaat tttaactgta aacagtaacg ttgcacgtaa tattgctagt aatataaggg
    61741 cgatttatgt ggatgaattt caagatacta gagaattaca atacaatgta atagctaaat
    61801 tacttcaaaa caaccctcaa attcagtcaa tgtttgttgg agatattgac caagcaattt
    61861 atggatcatt agatggtata gctaaatcag ttgaagaact agaaatgcta actagtcaca
    61921 cttttcaatc aaagacgcta catggctgtt acaggtctaa tcagagatta gtagacttct
    61981 actctaattt tcagagttgt ccttacgaga ttgaaagcag agggaataat aaaaacgacc
    62041 gtggttttat aagttatgat tgcaaagtta ctaaggagga tttacccaac ataataaaaa
    62101 atataataaa ggaaaagatt gaaagcggca ttcatgaaaa agatatttgt gtacttgctc
    62161 ctcaacacta tcctctgttt tcactgggtg agtatttaaa gaaagaatta ccgtattgca
    62221 attttgatgc tataaatata tcaccaatta aggtaaataa tcatagttta tttttcaagt
    62281 tagcaatttt gtactttact gaatcaggtg aaaaggttcg aagaagaaag ctaattgcaa
    62341 acgatatttt aattatatta aaaaatgaat ttggaataga agttaaagat tattttattg
    62401 acttagattt attacagcta ataaacagtg tgaaaagaat gtatagtgga gacgacaacg
    62461 gtgttgattt atacaaattt gttaccaaac atatatttgt taatcttaat attgacgaga
    62521 aaaattaccc gtctattttt aagcactatc tattttttat taacgaagta gaagatcgga
    62581 taaaaaataa ttcattatct agtagtgtat ctagttttaa gaagatgttt aaatctcgag
    62641 atggtatcac acttactaca gcacataaag ttaaaggaaa tgagtatgat actgttatcg
    62701 ctattaatct tctaaacggg aaaattcctc attggaatga aatttttaat gtttctgata
    62761 aaggaattag ttcagcgaga aaactactat acgtaatttg ttcaagagca aaaaataatt
    62821 tatttctttt ctcagaggtg ggttatttta cgagtaaagg agacttgctt tatcccactc
    62881 aattattaga taaaatagaa tttgattata atatttaaaa tacctaggta gtcgttgttt
    62941 taaatatagt aggaatcgga cgctcagtac ggagcgtcta tttttttacc caattttgaa
    63001 aggaagtgaa cttatgaaaa taaaaaatca agaatcaaaa ggtcgctctc ccccctttaa
    63061 aaccatcaca caaataagat tcattcaaac ataaaaacag aaaggatagg taaaaatatg
    63121 gaacttaaat atgtcattcc caatatggaa aaaacatttg gacaattaga atatgctggt
    63181 gaagggaaca ttgaacaacg tcgaataaat ggcagaccaa ccattctctc tcgtagttac
    63241 aatttatact caacgattca acgagcagat gatattgttg tcattcttcc ctccgaagct
    63301 ggcgagaaac attttgaatc cgacgaaaaa gtcaaactca tcaacccaca tattaccgca
    63361 gaaggttata aaattggcaa tcgaggattt accaattaca ttatgcacgc agacgatatg
    63421 gtgaaagcat aagaaaggaa aggtgaaaaa atatgagatt agcagaaggt attgtgattg
    63481 aaaaagacca gacatttggc acattgaaat tttccgcctt gcgtcgtgag gttcgtatcc
    63541 agaatgaaga tggtacggtt tccgaagaaa ttaaagaacg tacctatgac ttaaaatcaa
    63601 aaggacaagg acgcatgata caagtcagta tccccgcttc tgttcctttg aaagaatttg
    63661 actacaacgc agaagtggaa ttaatcaatc ctgtggcaga taccgtagcg acggctactt
    63721 ttcgaggggc agacgttgat tggtacgtga aagcagacga tcttgtatta aaaggacaga
    63781 caaaacctca tcagaaatat aaaaaagaag cgtccgaaag tgaaaaatag gtgttgctta
    63841 tgacaaacac accattgatt ttgaaagaaa ttccgaagga tgaagccatt tcttttattc
    63901 ggcaatacca ttattcaaag atactcccta gattgtgtaa atactttcta gggatttttt
    63961 cagaagaaaa attattaggc gttgtggaat taggctgggg tacgcaaccc ctacaaacca
    64021 tacgcaaact ctttcccgac agttcccttc aaaccacaga ttatttagaa attggaaaga
    64081 tgtgttttct tccagaaatg aatcaaacca attattttgg cagtcaagct ctttcagctc
    64141 taattaagtg gttgaaagaa catacggact gtcatttttt atatacactg gcagatggaa
    64201 ttgagggaaa atgtggctat gtctatcaag cgtccaactt cttttactgc gggtatttca
    64261 agacaagtgt ctatcgtgat aagcagtcat gggaaaagat acaccctcga agtgctcgcc
    64321 ttttattaga ggaaaatgct cgctttgaac aggtagagaa aaagcattgg ctttcccagg
    64381 cattttgcga atacaaaggg attgagaaaa tcaatggacg catgtttcgc tatctctatc
    64441 cgttgacaaa agaagcgaaa aaactgttag gacacactct ctatcgacgt cattattatc
    64501 cgaaagaaaa aaatttacgc tttgaaaagc gaatcgctta tcagaaatat gaagccattt
    64561 ctcaaccaac ttttgataaa caggctcgta tctacaatac acaattattt tgataggtgg
    64621 aaaggaggat ttttatgcca ttgcttcatg acagaggaga gcgaatcaaa gccaacgata
    64681 agcacttggt ctatcatttt gtactaattt cattgctggt agtttttcta gtcgtcctac
    64741 tcccttttca ttggagagcg ttacaatcgg tgaactggca agcagttcag ttagatacat
    64801 ttttctatca acttcatacg ccatactttt ggagcagtat tctcactgct ctttttgtat
    64861 gcggacttat cagctggctt tattatcact atcgtataga ttctataaaa cagttagagc
    64921 accgtcaaaa gttagctcgt atgattttag aaaatcattg gtatgaagcc gaagaaactc
    64981 aatcagaggg attctttaaa gatttaccca gcaagaaaac caaacaacga atccgccatt
    65041 ttcctaaaat atattatcga atgaaagatg gactaatcca tattcatgta gaaatcacct
    65101 tagggaaata tcaagatcag cttttgcacc tagaaaacaa actagaaaca ggattgtatt
    65161 gtgaattagt ggaaaaaacg ttgaaagatt cttatgtaga gtatgtccta ctttatgata
    65221 ctattggcaa tcgaattggc attgaagacg tggtagctca agatggacgt gtcaaattga
    65281 tggaatcggt ctattgggag ttcgattctc tccctcacat gttaattgct gggggcactg
    65341 gtagtggaaa atcctatttt attctcacat tgattgaatc tctcctgcat acaaatgcaa
    65401 agctttatat tcttgaccct aaaaatgctg atttggcaga cttaggggcg gtcatgaata
    65461 atgtctatta ccgtaaagaa gatatgttgg catgtatcaa tcaattttac gaagatatga
    65521 ttgatcgcag tgaaaccatg aaacaacacc ctaactataa aacaggagaa aattatgctt
    65581 atcttggttt gtctgccaat tttcttattt ttgatgaata tgtggcaatg atggatatgc
    65641 taggtcgtga aagtaccacc gttattcata aactcaaaca aattgtaatg ttaggacgac
    65701 aagcaggctt ctttttaatt cttgcctgtc aacgtccaga cgcaaaatat tttagtgatg
    65761 ggattcggga caactttaac ttccgtgtgg ctttgggtcg tatgtctgaa atgggctttg
    65821 gtatgatgtt cggaagcgat acacaaaaac aatttttctt aaaacccatc aagggaagag
    65881 gttacgtgga tacaggaaaa agtgtgatta gtgagtttta tacacccctt gtaccaaaaa
    65941 ggtacgattt cttaggagaa ataggaaaag tcattcaaaa aaagcaatct gagcctgtac
    66001 cgcacgaagt gaaaggtaca ggttcagact tgctttgatt ggtgtggcgt tagccacgcc
    66061 aatcctttag ccccctctat ctaacagggg ggcacaaata caactgaaaa caggcaattc
    66121 tcatcaacca atgttgatgg tacaaaggat tgcggaaaat atgaaaggtg taaactcaag
    66181 ggtcatagtt tacatctttt ttagattgga ggtttgcgaa tggaaaacga aaaaatttgg
    66241 attaaggaat tgaaagaaaa gcgactggct tatggcgttt ctcaaaataa actggcggtt
    66301 gcttctcata ttaccagacc ttacctatcg gatattgaaa caggcaaggc agtccctact
    66361 caacaggtga aagaagattt actgaacgct ttggaacgct tcaatcccga taacccattg
    66421 gagatgttat tcgactatgt acggattcga ttccctacca atgatgtggc tcaaattatc
    66481 ggtgaggttt tacgtttgaa tatggattat atgctacacg aagactttgg ctattattct
    66541 tatcccgaac actatcgttt cggtgatatt gttgtcctag tctctcatga tgtaagtaaa
    66601 ggtgttttat tagaactgaa aggaaaaggc tgtcggcaat ttgaaaactt tctattggct
    66661 caacatcgga gctggtatga tttctttcaa gattgcatgg aacataaagg tattttcaaa
    66721 cgcttggatt tagctatcaa cgataaaaca gggattttga atattccaga tttggcaaag
    66781 aaatgtaaac aggaagaatg catttccgtc tttcgaagct ttaaaaatta tcgcagtggt
    66841 gaattggttc accgtgatga aaaaccatac atgggaaaca cactttatat tggctcatta
    66901 aaaagtgaag tctatttctg tatatatgag aaagattatg agcaatacgt gaaaaatgat
    66961 gttcccttag aagacgcaga agtaaagaat cggtttgaaa ttcggttaaa aaatgaccga
    67021 gccacccaag ccatgaaaga tttattggca catcaacagg cggaaaaaac agcctttgaa
    67081 attatcaatc gctatatccg ctttgcagat aaagacgaca ctaaacgtcg gagtgattgg
    67141 aaaactaatg aacgttggga atggtttatc ggtaaaaatc gtggagcatt acgcctaacc
    67201 acacagccag agccttattc ttttgaacga acattgaact ggttacatca tcaagtcgcc
    67261 cctacattaa aaatcgcaag cattttagat gttctcaacg gtacaaccat tatctccacc
    67321 atgattcagg aagccaaact gacagaaaaa catgagaaat taattgaaca acaacatcta
    67381 gccatggagg atttgattac atgagccttt taacaaaaga attaaagaag ttagggtttc
    67441 agtgtggcat tgagtttcaa gcgtatatac aaaatacagg gaaatatacg tctctcatta
    67501 ttgagggaaa acggcaagct ggtgatacca tctataccta tgatttttac aaggtgagat
    67561 tttataataa ttataccaat cgagtaaccg tctatggaga gcatttaacc ccttttcaat
    67621 tattaaggcg tgtaaaaagc tatatctatt atcgagaaaa atatcttaag gaaaggagga
    67681 caatcacatg aattttgggc agaatttgta caactggttc ttggataatg cacagtcatt
    67741 ggtattgtta gcgattgttg tcattggact gtttttaggt tttaaacgag aattttcaaa
    67801 actcattggc ttcttgatta ttgctctaat cgccgtcgga cttgtgttca atgcagctgg
    67861 cgtgaaagat gtgttattaa acttatttaa ccgaatcatt ggtgcttaac agatattttt
    67921 catgataaaa taggaagtat atattttgtt atgaaaggat ttatgaatat gtttacaaat
    67981 gatcaattta aatctctttt aattaaaaca ttagaaagaa agagctcttc aaattattat
    68041 gaaggaggta acgagattgt ttctaaaatg aaaatatcag aggtaacttt agatgagact
    68101 gacgatttta cttattataa aggatataaa aagggctgga atacgctttg cacatatctt
    68161 aaaataagag ttccttttga tgatttagac ttttttgaaa gtcataaaga tttgattacc
    68221 cagacagcaa gctccatata tgataaacaa ggtgataatg tattagtgga tactatttta
    68281 gtaccacttc cagagaatta cgaagtaatt aactttagtc agttgaaaat tagtgatgtg
    68341 gtttcacaag ctattgaaga cgctgagtct tttatgagta atggtgaata tcaacgtgcc
    68401 tttgacagag ttcacactgc ttttcatgga tatttaattg aaatactaaa aaaatatgaa
    68461 attacagttc ctagagacga aaatctatct aaattatata gtaggataca acaattaatt
    68521 gaaaaagaaa ttcaacctac tgaacttgct gatatagtga agacaacgat aaggtcatca
    68581 aatggaatga ttagctctct taatgaagca agaaataggc attcacttgc acaccctaat
    68641 acaaatatta ttggaaagag agaagcaaaa ctaataatag gtatttcaag tacagttaca
    68701 gattatatta gcggatacct tgataagtag cgtcattaac tgattgctac tttttttatg
    68761 actattttta taaaaaggat gtgataagaa ttggaaatga aagtctatgt ggcaaattta
    68821 ggacggtata atgaaggtga attagtcgga gcatggttta ctccaccaat tgatgaggaa
    68881 gaaatggcag aaagaatcgg tttaaatgag gactacgaag aatatgcaat acatgatttt
    68941 gagcttcctt ttgatgtgga cgaatacacg ccgattagtg aaatcaaccg tctatgtgaa
    69001 gccattcaag aaatcgaagg tacacctatt tataatgaac tcaaagaaat tcaaggcatg
    69061 tggtttagta gcttggaaga attactggaa aacaaagagg atattcattg ttatagtgat
    69121 tgtgattcga tggaagatgt cgcccgttat tacgtggaag aaacaggaca gcttggtgaa
    69181 gtcccttcca atttacaaaa ttatattgac taccaatctt tgggacgtga tatggaaata
    69241 gagggtaatt acctagttac ctctcatggg gtatttgaat attgtcagta agtttaacaa
    69301 tccgtgttat aattaaatta ataaatagca cggagaggta taaattatgg taaatgtatt
    69361 tgaaaatctt aaactattaa aactagacat gaaagataaa ggctgggtga tagattcctt
    69421 ttactttcgt tacaaacagc aaaattatat tgtacttgtt aagctatttg aaaaagagga
    69481 aaaagttcca gaatatgctc tgttaaaact agaattttta aaggaaaacg atttttcaga
    69541 tatgctagct gtctatgcta attcggtaaa attatataca gacacgaaaa caataagaga
    69601 atattttggt atcgaataca gtagtaactt gggagatgtt ttatttcaat ttagccaaac
    69661 tcttgctcga tttattccga cagaagttag tgagaagaaa aatgaagacc aaaaagaagc
    69721 catgtgtttc tcattaagtc aaagtgattc agaagatccc agaaaaaaat attgtttttc
    69781 agttagaaga aatcctttaa agggaaatgg tgagctggga aaacgaagtc cttttaatga
    69841 caataaaacg agattgtata gacccagctt atatgaacga ttagggtcag ataccaattt
    69901 aagtttcaga tattcaatga atccagatga tgaagaaact gatgaaggta ttattgcaaa
    69961 atggacaaaa aataaaattg aatagttaaa gcattgaaag agcaatcacc tattttgatt
    70021 gttctttttc tatttttacg gaaaggacgt gaagacatga aaaaaataag aagttacacc
    70081 agtatttggt cagtagaaaa agtgatttat gcgattaatg atttacaact ccctttccca
    70141 attaccttta cgcaaatgac atggtttatc gtttctttgt ttgtcgtcat actctttggc
    70201 agtttaccac cactttctct gattgacgga gcactactca aatacttagg gattcccatt
    70261 gttctcactg ggttcatgtg ccaaaagacc tttgacggaa agaaacccta tggatttcta
    70321 aagtctatca ttacctatgc tctacgccct aaagtaacct acgctggcaa acaaatacga
    70381 ttaaaaaaag aaacaatgaa tgaatcgatt acgattgtaa ggagtgaaca actagatggc
    70441 atatccgatt aaatatatgg aagataatct cgtatttaat catgatggcg aagtattcgc
    70501 ttattatgaa ttaattccct ataattacag ttttttaagt tccgatgaaa aaattcaagt
    70561 tcatgataat ttctgtcaat tgattgccca aaatcgtgat ggcaagattc atgctctgca
    70621 actagcaacc gaatcaagta ttcgagccac acaggaacaa tcgaaaaaag aaatcactgg
    70681 acgattaaaa gagatagctt acgaaaaaat agatgaacag accgaagcgt taatttctat
    70741 gattggtgac aatcaagtag actatcgctt ttttattggt tttaaactct acctcaatga
    70801 acaggaagta tccgtaaaaa atgttgggaa agaaattcaa aaagcatttg cggaattctt
    70861 tcatggtgtg aatcacaaat taatgggcga ttttgtttct atgcctatgg cggaaatcga
    70921 acgcttttct aagatggaac agttgttaga aagtaaatta tccagacgct ttcagattcg
    70981 taaattggag aaagatgatt ttggttatat tattgaacat ctttacgggc aaacaggtgt
    71041 cccttttgat gactacgact accatttacc gaaacgatac gaagataaaa aagtgttggt
    71101 aaagaaatac gatattctca aacccactcg ctgtttaatc gaagaaaatc aacgctattt
    71161 acggattgaa caggaagata ccactactta tgtggcgtat tttacaatta atagtattgt
    71221 tggtgaattg gatttcccta atagtgaaat tttttattac cagcaacagc agtttacttt
    71281 ccccgttgat accagtatga atgttgaaat tgtcgccaat aaaaaagcct tatctaccgt
    71341 tcgcaataaa aagaaagaac tgaaagattt agatagccac gcatgggaaa gcgacaacga
    71401 aaccagtact aatgtggtgg acgctttaga atctgtcgat gaattagaaa gtaatttaga
    71461 ccaaaccaaa gaatctatgt acaaactaag ctatgtggta cgggtatcag caaagaattt
    71521 ggacgagctg aaacaacgtt gtgatgaagt aaaagatttt tatgatgatc tgtctatcaa
    71581 attagtacga ccttttggcg atatgctagg cttgcataat gaatttattc cctcaagcaa
    71641 gcgatatatc aatgactata ttcaatatgt cacgtcggat tttttggctg gtcttggttt
    71701 cggtgctaca caaatgattg gtgaaaattc tggtatttac gtcggttaca atctcgatac
    71761 aggcagaaat atttatctcc aacctagcct tgcaagtcaa ggaattaaag gctctgtaac
    71821 aaatgcatta gcgtccgctt ttattggttc attaggtggc ggaaaatcat tctctaacaa
    71881 tatgctggtc tattattcag tactctttgg cggacaggca accattgttg acccaaaagc
    71941 tgaacgtggt gaatggaaag aaaccttacc tgatattgcc catgaaatca atattgttaa
    72001 tctcacgagt gagaacgaca ataaagggtt acttgaccct tatgtgattt taaaactccc
    72061 gaaagattca gaaagccttg ccattgatat tctcacgttc ttaacaggta tttccagccg
    72121 agatagcgag aagtttcctg tcctgcgtaa agctattcgg agtgtaactc aaagcaaaca
    72181 acgagggttg ttattggtga ttgatgaatt gcgaaaagaa gatacgccca tcagcaatag
    72241 tattgctgac catatcgaaa gctttgtcga ttatgatttt gcccatctgt tattcagtga
    72301 tggcagtgtc acccaatcca ttagcttgga aaaacaactc aatattattc aagtggcaga
    72361 tttggtctta cccgattcca atagctcttt tgaagaatac actaccatgg aattattaag
    72421 tgtggcaatg ctgattgtca ttagtacctt tgctttagac tttatccact ctgaccgttc
    72481 catttttaaa attgttgacc ttgatgaggc ttggagtttt ttacaagtgg cacaaggaaa
    72541 agctctatct atgcgattgg ttcgagcagg acgtgccatg aatgcagggg tctatttcgt
    72601 tactcaaaac gcggacgatt tactagatga aaagatgaag aataatattg gcttgaaatt
    72661 tgcctttcgt tccactgacc tagtggaaat caaaaagacc ttagaatttt ttggtgtgga
    72721 caaggaagat gaaaacaatc agaaacgctt acgtgaatta gaaaatggac aatgtttagt
    72781 ttcagacatc tatggtcgtg taggggttat gcagtttcac ccgatttttg aagagttgct
    72841 tcatgccttt gataccagac cgcctgtgcg aaatgaggtg gaagaatgac acaaaaacaa
    72901 aagaaatttc ttcactatag ttggataacg ctcctttgtg tgggcgttat tttactttta
    72961 ttaggcacgc tgggcaatgc agtacaagcg acaggcttag ttgatgaaac cattgataca
    73021 agcaatgaat actccaagta tggtttgaat caatatcagc ttgattatta tgtggacaat
    73081 agctggggct ggcttccatg gaattggagt gatggcatag gacaatcggt gatgtatgga
    73141 ttgtatgcca ttactaattt tatttggaca atttctcttt atctatcgaa cgccacaggt
    73201 tatttggtga aagaagccta tgccttagat ttcattagtc aaacatccca agcaattggc
    73261 gaaaacatgc agacgattgc aggcattaca ccgaatggct tttccagttc agggttttat
    73321 gtcggtttcc tccttctttt tattctcatt gttggaatct atgttgccta tacaggattg
    73381 gttaagcgag aaacgacgaa agtgatacga gctgttttaa actttgtcgt ggtgtttatt
    73441 ctatcggctt cctttattgc gtatgcaccc gattatattg cgaaaatcaa tgatttttcc
    73501 aaagatgtca gtaccgccag tctgaatatt gggacaaaaa ttgttcttcc taacacggat
    73561 agtcaaggga aagacagtgt ggacatgata cgtgacagct tattctctgt tcaagtaaag
    73621 caaccatggc tattgcttca atatggctcc actgatgtag aagcgttagg ggaagaacgt
    73681 gtggaaagtt tattgtctac cagtccagat acaaacaatg gtgaagatag agaaaatgta
    73741 gtgattgaag aaattgaaga tcatgacaat acctatttaa ccctaccgaa gacgatttcc
    73801 agattaggaa cagtcttctt tttgtttgta ttcaatattg gtatctcgat ttttgttttc
    73861 cttctaacag gaatcatgat tttttcgcaa gtgctattta ttattttcgc tatgtttttg
    73921 ccaatcagtt tcctattaag tatgttgccg agttttgatg gcatgggcag gcatgccatt
    73981 accaagttat ttaatgtgat tatgacaagg gctggtatta ccttgattat taccgttgcc
    74041 tttagtattt ccactatgct ttattcgctg tcagcaagtt ctcccttttt catgattatg
    74101 tttttacaaa ttgtgacctt tgcagggatt tattttaaac tgggcgattt aatgagccta
    74161 ttcactttac aaagcaacga ctctcaaaac atgggcagac aagtgtttcg cagacctcgt
    74221 caaatgatga atcgacaaac cagaagattt caacgcagta tgagtaagat ttttcgtgga
    74281 aaagcagggt caacgaagca aaagacaatg acaacaaagc agaatcaaac caataaagct
    74341 aaccatactc gtcaaaatga acggactaca ccaaagaaag aaacagcact ttccaatgtg
    74401 aaaaagcaac aaggcggtat cgggcaacga ttaggtgaaa agacagccca tgtattggac
    74461 acgaaaaatc gtctagtcaa taaaagaaag caggcaaaac aacagataca ggcgacacca
    74521 acccatgtca aatatgccct tcatcaagga aaagagaatg tcactcataa tgtaacagac
    74581 tttaaacaat ctatggcaga taccaaagct caacgcaaac aacagcgtat gaaccagcag
    74641 gagcaaaaac gaaagaacat tgctcaaaag cgtttggagc tggataaagc aaaagaaaaa
    74701 agacgaaaag aaaacccatc atctcctgtt cagaataacc agcagcatgt tcgcaagcgt
    74761 cagcaaaccg tcacgcctgt tttgtcacaa aacactaaac gtgaaaatca tcagcgacca
    74821 ttgaaaaaag agcaaaaaca aaagacacca ccgaagcaat tcaatcagag gaagctaaat
    74881 aaaagaacgg ataagcgagg acaacaaaca tgaagctaaa aataacagtg atttgtagtg
    74941 tggtcttctc tctcttcttt tttctcttat tattcctagt cattttcttt gcagatgata
    75001 cggacagtgg cgaaaacaac aaggattctt ctattccaca aggcggtgtg accgtttcac
    75061 cagaagtgtt ggcacaccgt ccgttgattg aaaaatatgg taaggaatat gggattgaag
    75121 actatgtttc ttatatctta gccattatgc aagtggaatc gggcggtaca gcagaagatg
    75181 ttatgcaaag ttccgaatct ttgggtttac cgcccaacag tttgagtacc gaagagtcca
    75241 tcaaacaagg ggttaaatat ttcagtgaat tattaaccag tgcagaacaa caaggagtgg
    75301 atatagattc tgttatccaa tcttataatt atggcggtgg ctttttaaat tatgtgagga
    75361 gtcatgggaa aaaatatacc tatgaattag ccgaacagtt ttctaaagag aagtcgggtg
    75421 gtcaaaaagc agactatccc aatcctatag ccatacctgt gaatggtggt tggcgatata
    75481 actatggaaa tcagttttat gttcagttgg tttcacaata cctaaccgac acttccccaa
    75541 cagaatttga tgatgaaacc gtgcaagtca ttatggacga agccttgaaa tacgaagggt
    75601 ttccctatgt ctttggaggg gcgtcgccta ccacctcttt tgattgtagt ggcttaatac
    75661 aatgggtgta tgacaaagct ggcatttctc tccctcgtgt cgcccaagat cagtatgacg
    75721 ctacgcaaga aatctctatg gaagaagccc aagcaggcga ccttatcttc tttcattcaa
    75781 cctataatgc aggcacatat gtgactcatg tggcgatata tttagaggga aatcgctttt
    75841 atcatgcagg cgacccaatc ggttatggcg acttaagcag tcgttattgg caagaccatc
    75901 tgattggggc tagacgtgtt attcataact aagaaaggaa tgaatcaaat gattataaaa
    75961 atcgagcgaa aagaaaagaa ggagaaacca aagaaatcta aaaaaccgag caagcaaaga
    76021 aaagttccga tgattaaagt tggcacgcat aagaaattaa cctttgtttt atgggtttta
    76081 ttgattggta gtgtcggatt tggaatctat aaaaatttta ctgccattga cactcatact
    76141 gtccgtgaaa cagaaatcat taaacagcag attgtcgata ccaaccaagt agaaagtttt
    76201 gtgaaatcct ttgcgaaaga ctacttttcg tggcaacaat cccaagaagc cattgataaa
    76261 cgaaatgaaa aattgaccca ttatttgacg gaagaattgc aggtattaaa tgaagaaatg
    76321 attcgtaagg atattcctac tagttctagt gtgaacgata tacaggtgtg gcaggtttct
    76381 caagtgaatg agaacacctt tgaggtactg ttttctgttg aacaagttat taccgaagac
    76441 aaagacaagg aaactatatc gtctagcttt catgtggttg tccatataga tgaatcagat
    76501 aatatggtta ttatcaaaaa tccgacaatg agtaagaaac ctcaaaaatc ggactaccaa
    76561 cccaaacagc tagaaagtga ccatacagta gatacagaaa cgatggacga aatcactagc
    76621 tttttagaaa cgttcttcca gctctatcct accgccacag aaaaagaatt gacttactat
    76681 gtaagtaatc atgtgttacc tatgattaac aaggaatatg ttttcgagga attggtgaat
    76741 cctatcttta ccagaaaaga taaccaagta atcgtgaatg tcgctgtgaa atatttagat
    76801 caagaaacaa aggcaaccca aatctcgcaa tttgagttga tattagaaaa acaagataat
    76861 tggaagattg taaaataaca aatattggta catgattaca gatactttgt aatcatgtac
    76921 tctttttgat aaaaaattgg agattccttt acaaatatgc tcttacgtgc tattatttaa
    76981 gtgactattt aaaaggagtt aataaatatg cggcaaggta ttcttaaata aactgtcaat
    77041 ttgatagcgg gaacaaataa ttagatgtcc ttttttagga gggcttagtt ttttgtaccc
    77101 agtttaagaa tacctttatc atgtgattct aaagtatcca gagaatatct gtatgctttg
    77161 tatacctatg gttatgcata aaaatcccag tgataaaagt atttatcact gggattttta
    77221 tgcccttttg ggtttttgaa tggaggaaaa tcacatgaaa attattaata ttggagtttt
    77281 agctcatgtt gatgc
//
LOCUS       DAPBBR010000006        74441 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPBBR010000006 DAPBBR010000000
VERSION     DAPBBR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 74441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.006"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(161..445)
                     /locus_tag="RD488_000397"
     CDS             complement(161..445)
                     /locus_tag="RD488_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656499.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="RD488_000398"
     CDS             complement(463..1353)
                     /locus_tag="RD488_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDT7656500.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="RD488_000399"
     CDS             complement(1373..1591)
                     /locus_tag="RD488_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HDT7656501.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="RD488_000400"
     CDS             complement(1561..3261)
                     /locus_tag="RD488_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDT7656502.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="RD488_000401"
     CDS             3528..4301
                     /locus_tag="RD488_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656503.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="RD488_000402"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="RD488_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HDT7656504.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="RD488_000403"
     CDS             complement(5125..6096)
                     /locus_tag="RD488_000403"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7656505.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="RD488_000404"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="RD488_000404"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDT7656506.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="RD488_000405"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="RD488_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDT7656507.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="RD488_000406"
     CDS             complement(9051..9875)
                     /locus_tag="RD488_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7656508.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="RD488_000407"
     CDS             complement(9848..10528)
                     /locus_tag="RD488_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7656509.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="RD488_000408"
     CDS             complement(10551..11489)
                     /locus_tag="RD488_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HDT7656510.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12597)
                     /locus_tag="RD488_000409"
     CDS             complement(11734..12597)
                     /locus_tag="RD488_000409"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDT7656511.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="RD488_000410"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="RD488_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7656512.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="RD488_000411"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="RD488_000411"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDT7656513.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="RD488_000412"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="RD488_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDT7656514.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="RD488_000413"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="RD488_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDT7656515.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="RD488_000414"
     CDS             complement(19463..20704)
                     /locus_tag="RD488_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDT7656516.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="RD488_000415"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="RD488_000415"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDT7656517.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="RD488_000416"
     CDS             complement(21731..22654)
                     /locus_tag="RD488_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656518.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23393..24679)
                     /locus_tag="RD488_000417"
     CDS             complement(23393..24679)
                     /locus_tag="RD488_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7656519.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24672..25940)
                     /locus_tag="RD488_000418"
     CDS             complement(24672..25940)
                     /locus_tag="RD488_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7656520.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26192..26653
                     /gene="mscL"
                     /locus_tag="RD488_000419"
     CDS             26192..26653
                     /gene="mscL"
                     /locus_tag="RD488_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDT7656521.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26712..27158)
                     /locus_tag="RD488_000420"
     CDS             complement(26712..27158)
                     /locus_tag="RD488_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7656522.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27251..27496)
                     /locus_tag="RD488_000421"
     CDS             complement(27251..27496)
                     /locus_tag="RD488_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDT7656523.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27611..28189)
                     /locus_tag="RD488_000422"
     CDS             complement(27611..28189)
                     /locus_tag="RD488_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7656524.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28266..28796)
                     /locus_tag="RD488_000423"
     CDS             complement(28266..28796)
                     /locus_tag="RD488_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDT7656525.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28800..29660)
                     /gene="rlmB"
                     /locus_tag="RD488_000424"
     CDS             complement(28800..29660)
                     /gene="rlmB"
                     /locus_tag="RD488_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDT7656526.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29653..30048)
                     /locus_tag="RD488_000425"
     CDS             complement(29653..30048)
                     /locus_tag="RD488_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDT7656527.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30045..31457)
                     /locus_tag="RD488_000426"
     CDS             complement(30045..31457)
                     /locus_tag="RD488_000426"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDT7656528.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31454..31990)
                     /gene="cysE"
                     /locus_tag="RD488_000427"
     CDS             complement(31454..31990)
                     /gene="cysE"
                     /locus_tag="RD488_000427"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDT7656529.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(32076..32315)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32312..33772)
                     /locus_tag="RD488_000428"
     CDS             complement(32312..33772)
                     /locus_tag="RD488_000428"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDT7656530.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33942..35099)
                     /locus_tag="RD488_000429"
     CDS             complement(33942..35099)
                     /locus_tag="RD488_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDT7656531.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35133..36503)
                     /gene="radA"
                     /locus_tag="RD488_000430"
     CDS             complement(35133..36503)
                     /gene="radA"
                     /locus_tag="RD488_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDT7656532.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36566..37093)
                     /locus_tag="RD488_000431"
     CDS             complement(36566..37093)
                     /locus_tag="RD488_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDT7656533.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37323..38129
                     /gene="proB"
                     /locus_tag="RD488_000432"
     CDS             37323..38129
                     /gene="proB"
                     /locus_tag="RD488_000432"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDT7656534.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38126..39373
                     /locus_tag="RD488_000433"
     CDS             38126..39373
                     /locus_tag="RD488_000433"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDT7656535.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39449..39793
                     /locus_tag="RD488_000434"
     CDS             39449..39793
                     /locus_tag="RD488_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656536.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39910..40236)
                     /locus_tag="RD488_000435"
     CDS             complement(39910..40236)
                     /locus_tag="RD488_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656537.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40609..41810)
                     /locus_tag="RD488_000436"
                     /pseudo
     CDS             complement(40609..41810)
                     /locus_tag="RD488_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41927..42442
                     /locus_tag="RD488_000437"
     CDS             41927..42442
                     /locus_tag="RD488_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7656538.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42641..43087)
                     /locus_tag="RD488_000438"
     CDS             complement(42641..43087)
                     /locus_tag="RD488_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7656539.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43134..44612)
                     /gene="msr(C)"
                     /locus_tag="RD488_000439"
     CDS             complement(43134..44612)
                     /gene="msr(C)"
                     /locus_tag="RD488_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7656540.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44966..45595)
                     /locus_tag="RD488_000440"
     CDS             complement(44966..45595)
                     /locus_tag="RD488_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7656541.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45579..46043)
                     /locus_tag="RD488_000441"
     CDS             complement(45579..46043)
                     /locus_tag="RD488_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7656542.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46530..47798)
                     /locus_tag="RD488_000442"
     CDS             complement(46530..47798)
                     /locus_tag="RD488_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7656543.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48029..48766)
                     /locus_tag="RD488_000443"
     CDS             complement(48029..48766)
                     /locus_tag="RD488_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7656544.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48833..49402)
                     /locus_tag="RD488_000444"
     CDS             complement(48833..49402)
                     /locus_tag="RD488_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7656545.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49530..50402
                     /locus_tag="RD488_000445"
     CDS             49530..50402
                     /locus_tag="RD488_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7656546.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50744..51616
                     /locus_tag="RD488_000446"
     CDS             50744..51616
                     /locus_tag="RD488_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7656547.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51613..53571
                     /locus_tag="RD488_000447"
     CDS             51613..53571
                     /locus_tag="RD488_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7656548.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53822..54673)
                     /locus_tag="RD488_000448"
     CDS             complement(53822..54673)
                     /locus_tag="RD488_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7656549.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54796..55263
                     /locus_tag="RD488_000449"
     CDS             54796..55263
                     /locus_tag="RD488_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDT7656550.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55526..56008)
                     /locus_tag="RD488_000450"
     CDS             complement(55526..56008)
                     /locus_tag="RD488_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7656551.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56108..56971)
                     /locus_tag="RD488_000451"
     CDS             complement(56108..56971)
                     /locus_tag="RD488_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7656552.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57569..58417
                     /locus_tag="RD488_000452"
     CDS             57569..58417
                     /locus_tag="RD488_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656553.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58588..58929)
                     /locus_tag="RD488_000453"
     CDS             complement(58588..58929)
                     /locus_tag="RD488_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HDT7656554.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59015..59722
                     /locus_tag="RD488_000454"
     CDS             59015..59722
                     /locus_tag="RD488_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7656555.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59709..60032
                     /locus_tag="RD488_000455"
     CDS             59709..60032
                     /locus_tag="RD488_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7656556.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60121..61158)
                     /locus_tag="RD488_000456"
     CDS             complement(60121..61158)
                     /locus_tag="RD488_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7656557.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61605..62588)
                     /locus_tag="RD488_000457"
     CDS             complement(61605..62588)
                     /locus_tag="RD488_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDT7656558.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63004..63774)
                     /locus_tag="RD488_000458"
     CDS             complement(63004..63774)
                     /locus_tag="RD488_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656559.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63767..64702)
                     /locus_tag="RD488_000459"
     CDS             complement(63767..64702)
                     /locus_tag="RD488_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656560.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65296..66945)
                     /locus_tag="RD488_000460"
     CDS             complement(65296..66945)
                     /locus_tag="RD488_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7656561.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67140..68036)
                     /locus_tag="RD488_000461"
     CDS             complement(67140..68036)
                     /locus_tag="RD488_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7656562.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68029..68709)
                     /locus_tag="RD488_000462"
     CDS             complement(68029..68709)
                     /locus_tag="RD488_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7656563.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68710..69492)
                     /locus_tag="RD488_000463"
     CDS             complement(68710..69492)
                     /locus_tag="RD488_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656564.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69485..70402)
                     /locus_tag="RD488_000464"
     CDS             complement(69485..70402)
                     /locus_tag="RD488_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656565.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70405..70689)
                     /locus_tag="RD488_000465"
     CDS             complement(70405..70689)
                     /locus_tag="RD488_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656566.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71390..72010)
                     /locus_tag="RD488_000466"
     CDS             complement(71390..72010)
                     /locus_tag="RD488_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656567.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72091..72501)
                     /locus_tag="RD488_000467"
     CDS             complement(72091..72501)
                     /locus_tag="RD488_000467"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656568.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            72531..73709
                     /locus_tag="RD488_000468"
                     /pseudo
     CDS             72531..73709
                     /locus_tag="RD488_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT        21520 a        15817 c        13085 g        24019 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcta tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggag
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    23401 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    23461 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    23521 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    23581 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    23641 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    23701 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    23761 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    23821 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    23881 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    23941 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    24001 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    24061 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    24121 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    24181 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    24241 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    24301 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    24361 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    24421 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    24481 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    24541 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    24601 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    24661 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    24721 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    24781 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    24841 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    24901 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    24961 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    25021 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    25081 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    25141 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    25201 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    25261 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    25321 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    25381 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    25441 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    25501 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    25561 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    25621 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    25681 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    25741 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
    25801 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    25861 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    25921 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    25981 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    26041 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    26101 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    26161 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    26221 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    26281 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    26341 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    26401 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    26461 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    26521 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    26581 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    26641 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    26701 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    26761 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    26821 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    26881 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    26941 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    27001 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    27061 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    27121 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    27181 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    27241 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    27301 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    27361 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    27421 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    27481 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    27541 ttcaagttta ccataaaaaa aaaagaaatg caataaaaat aaataagaag ctcattaaga
    27601 tttttctaaa ttattcctca ttataaaatt tcaagtgttt ttttattttg agttttactc
    27661 tcccgtaagc gctcattact tgcttgtgat ccattgctaa acattcagcc atgtctacaa
    27721 aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc tatttttgaa aactggattt
    27781 cgcaattttc gattgcttct tttaataaaa gatgctgaat cgctaaaggt tcttgcaatg
    27841 tgatctctgc taaaaagtct ggtccttctg tctctatttt ttggtcgatt gagacttcat
    27901 ctttttgatc acgacgcttc agcgcgttct gcttcctcaa cagagaatag atttgattgc
    27961 ttataatgct tttataataa cttccaaagc taacaccttt gcttttttcg taagttctca
    28021 atgcctgata taaagcgatc cttgcttctt gttcccaatc ctcagaaaca taatttctta
    28081 aataataggt gtttttcaaa cgtagtaaaa gtggaaaata tttttgatac agggcagcaa
    28141 atgcttcttc gtcaccatta cgtgcagcgc gcaataactc ctcagacata aaataattcc
    28201 tccataaatt cgtttatgga ggaatcttat catcaatgat tcatcgaact gattagaacg
    28261 atatgttatt tattttttct cattaaatcg tccaattttt gggacaattt ttttaactgc
    28321 tcttcattcc atggagaatt acgtcggaaa tcaataaaat gcatatcttt attttcttgg
    28381 gctattgttt tttccgtttt ttttatcgtc ttatataatt cataagcaga agttcgtaat
    28441 gctccttggg aaaagatcat ccactgttct gctaaatcgc ttgtcgccac tgtcacttgt
    28501 gtcaaacggt cattcagctg accagcgatt ctctcgatat aactgtcagc cgtttcgtct
    28561 tctttcgtaa aaacaacatc caactggtat ttcttataat tttgttggat gcccggaact
    28621 agttgggcat cgaagacaac gatgacttcc attccttcat atttcgcata atttgataaa
    28681 cgatgtaaaa gagcttctct tgcatccgcc attttgtcct gctttttaag ctggacaagt
    28741 tccggccacg aaccaatcat gttgtagccg tctacaatca acagctgttt tttcatggtc
    28801 tactccccct gacgttggga aaaagcctga tacataagca aaccagcagc aacactggca
    28861 tttaagctct ggacgtgccc ggtcatcggg atcgtcagca attcatccat ttcttttttc
    28921 aatcctggac tcattccttt gccttcatta ccaatgacta aagcaattga tcctttggca
    28981 ttccattttt ggaagtttgt gccggtcata tctgtgccaa atacccaaaa tcctgtttct
    29041 ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg caacagggac atgttcgact
    29101 gccccagtgg aagtctttgt tacgataggt gtgattccaa ctgctcggtg ttttggtatg
    29161 atcacaccat cgacgccact tgcgtctgct gtccgtaaaa tcgacccaaa attgtgtgga
    29221 tcttcgatgc tatccaaaat caaaaagaag gggtcttctt ttttctcttt tgttcgttca
    29281 atcagttggt caagggataa atattcataa ggtgtaatcg caagaacgac tccttgatgc
    29341 acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa cccatttgac tggcacagct
    29401 tgttcacgtg cgatttcttt cagttcttct actttttctc ctcgtgaatc ttcttgaaga
    29461 aagagtttat tccctcgccc ttgttgtagc gcttctactg cggcatggtg cccaaagacg
    29521 aaattatctt ctaatgcttc ttcattttga tcagaaactg actgatttcg tccagtttgc
    29581 tttttatttg aatatctatt ttgttttttg tcttcaaatc cacgtttcga ttgatgtttg
    29641 tttgttcttt ctttacccat ttttttcacc aactttctga atacaccagc ggatcaattc
    29701 ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc atgagcgctt cgaaccctgt
    29761 tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc gtatggcttt tagcatttct
    29821 tcctctgcga taataaagtt cttcttcttc tgtcaaaaga tgttcttcca gcatttgctg
    29881 aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt gccgcacgat gcagcttatt
    29941 gggttttgtt tctccttgat caatcaggtg gtcacgaaca tagatttcgt aaatcgcatc
    30001 tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa tctctcatgc ttctcttctc
    30061 catcgggttc cttgcggtgt atcttctaat aagatccctt tttctttcaa caaatcacga
    30121 atttcgtcgc ttcggacaaa atcacgattg cttcttgctt gatttcgttc ttcgatcaat
    30181 tgttcaatct cttcatctaa taactcttct gctgtaaata aaataccgaa gatcgaaagc
    30241 cattgcgaga ataaagcttc tccttgtgcc aagacagcgg cagaaacttt cggctggtct
    30301 agataagtgt tcagccactt agcaagctca tagaccactg tgatcccatt tgctgcatta
    30361 aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat tttctaacaa agcgatttta
    30421 tccgcatcat ctgccaaatt ctctgaggca gtttcttggc ggaatttcaa attgtcaaac
    30481 gtattcttca gtcgttgtaa attggtggct gcttctttca tcgtcgtttc actgtagcgg
    30541 atcggacgac ggtattgtgt ggtcgccatg aagaaacgca agacttgtgg atcaacgttt
    30601 ttgatcattt catgtacagt gatgaaattc cctagagatt tactcatttt ttcatcgtct
    30661 tcgccaatcg ttacatagcc attgtgcatc cagtaattag cgaatttttt ccctgttttc
    30721 gcttcacttt gtgcgatttc attttcatga tgaggaaatt ctaaatcttg cccgccacca
    30781 tggatatcga tcgtttctcc taaatgtttt gttgccataa cggaacattc aatatgccaa
    30841 ccgggacgtc ctttgcccca tggtgaatcc caagaaatct cgccaggttt tgcttgtttc
    30901 cataaagcga aatctaatgg gtcttctttt tgctgctgtt cttcccctgt acgctgactt
    30961 gctccgactt ccagttcatc gatggattgg tcacttaatt tcccataatt ttcaaattta
    31021 cgggtacggt aatacacatc acctgaagat tcataagcat agcctttttc aaccaacact
    31081 tgaataaatg ctaaaatatc tggcatatga tccatgactc ttggatgcag tgtagcaggc
    31141 tcgacattca acgctttcgt atcttcttca aatgctcgga tgaaacgatc agcaacttct
    31201 ggtgctgtaa tacctaattc gtttgctgta cggatgattt tatcgtctac atccgtgaaa
    31261 ttcgatacga aatcgacttt atagcctcga tattcaaaat agcgtcgaat tgtatcgaaa
    31321 gcaatggtgc tacgagcatt tccgatatgg atataattat acacagtcgg tccgcagaca
    31381 tacataccga catgtccctt ttgtataggg atgaattctt ctttttttct ggtcaatgta
    31441 ttgtagattt ttatcattct gatctcctca ctttttctcc tttgattcga acgacttttg
    31501 ctggtactcc taccgctgta gcgtcgtctg gaacatcttt caacacaacg gcacctgcac
    31561 cgattttggc gttttttccg atcgttaccg gtcctaatat ctgcgcattc gcagagagca
    31621 tggctccttg tttaacagtt gggtgtcttt tacccgtttc ttttcctgtg ccgcctaatg
    31681 ttacgccatg gaataaaatc acatcgtcct cgatttctgc ggtttcgcca atgacgattc
    31741 ccattccatg gtcgatgaac acgccagttc caatcgttgc tcctggatgg atctcaacac
    31801 cagttaggaa acgccagaat tgagcattga tcttcgccaa taaaaagagc cggtgctgat
    31861 ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa accagggtat gtcaaaacga
    31921 tctcagctgt cgaacgtgca gccggatcgt ttctctttgc tgcatcaatc gctcgggtaa
    31981 accaactcat gactttccac tcctttcgta agaattttat gtaggaaatc atcttcttat
    32041 aaagaaaaga agcgcctttt aaataagttt ccttatcaaa agacgctttc cgcgtggttc
    32101 cacttttctt cataatcaat gattatctct gacagctaac gcctgttata cgttcttggc
    32161 tactttgttt cctataaaac agtttttcct gttttctgtg tttcgccaag accactccca
    32221 gaggcatttc ggcaaccatt cattgatacc ttgcaccacc cggtatctct cttgtaatga
    32281 tcagctgctt acttttttct gttcatcgtg tttagttcag tacttgattt aaatgtgcta
    32341 atgatttttc acgaccaagc aattcgatcg tttcaggcaa ttctggacca tgcatttgtc
    32401 ctgatacagc tacacggatt ggcatgaaaa gattttttcc ttttacgcca gtttcttttt
    32461 gaacagcttt gatggcagct ttgacagttg gagcatctac tacttccatt tgttctagct
    32521 gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc agcaagtact tcttttgctg
    32581 cttcattcaa tacaggatgt tcattgaaaa atagcgtaga cagatcaacg atttctgcag
    32641 catagctcat ttgaggttga tacaggctaa cgatcttctt cacccattcg attgtctttt
    32701 catctgggtt ttctgctaca cgtccatcag cgattagata aggcagacac atgtcagtaa
    32761 atgcatctag atccattgct ttgatgtaat ggttgtttac ccattgcagt tttttcgcat
    32821 cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa cattttgatc aattcttggt
    32881 gttcgaagat ttcgtcttcg cccacaggtg accagcccaa taatgcaata aagttgaaca
    32941 ttgcatctgg tagatagcct aattcgcgat attgttcgat aaattgcaag attgattcgt
    33001 cacgtttgct tagtttttta cctgtttcac tgttgatgat caatgtcata tgtccgaagg
    33061 ttggtggtgt ccagccaaat gcttcataga tcatcagttg ttttggtgta ttggcaatat
    33121 ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg atcatcgacc gcaacagcaa
    33181 aattataagt tggcatacca tcgcgttttt gtatgacaaa gtcgccaccg atattatcgg
    33241 attcgaacga aatagcgcct ttcaccatat ctgtaaatgc gtattctgta ttgcgaggca
    33301 cacggaaacg tacaacagat tctagacctt gtgcttcttt ttctgcttgt tcttcaggtg
    33361 tcaagttcgc acatgttcct gcgtaatgag gcatttctcc tcttgcgcgt tgtgcttccc
    33421 gttctgcttc taattcttct tctgtgcaat agcatttgta tgctcgattg ctagcaagca
    33481 gctgatcaat cagcggttga tagatttctt tacgttcaga ttgacggtaa gggccgtatt
    33541 ctccaggatt ttcaggagat tcatcccaat tcattcccaa ccaagcaagg ttttccaact
    33601 ggcttttttc gccatcttcg atattacgtt tttggtcagt atcctcaata cgaataataa
    33661 agtctccatc attgtggcgg gcaaacaaat aattgaataa tgcagttctt gcatttccaa
    33721 tatgcaggtg cccagttgga cttggtgcat agcgtacgcg tactttcgtc attttcttcc
    33781 tcttctttca aactagactt tgactaacag caaaaattcc gtcagttacg gcttctcaaa
    33841 tatcatttat ttaaagccac tcagcacaaa ttttaccttt tctaaggtaa atagtaaagc
    33901 caactggttg aatttcctta ccagttggct gaatttcttt tttattttga ttgtttagtc
    33961 tttttctctg tctctttttt attgtcgatt cctcgtcctg catgtgcagg tttagcaaag
    34021 atcatgcgtc cagcagctgt ttgaagggca cttgttacaa cgacttcgat acgttcattc
    34081 atgtaatgct gtccatcttc tacgacaacc atcgtgccgt catcaaggta ggctactcct
    34141 tgttggcgtt ctgtcccggc ttttactact agaacattca tcgtttcacc agggatgacg
    34201 actggtttta cggcatttgc caacgcattg atattaagaa caggtacatt ttggaattca
    34261 gagactttat tcaagttata gtcattggtt acaatgacac catctaaaag cttagccaat
    34321 ttgatcaatt tgctgtctac ttcactgata tcttcaaagt ctccatcgta catttcgaca
    34381 gatataccct cttctttttg caaggcattt aggatatcta atccgcgacg accacgcaca
    34441 cgtttcaaac tatcccctga gtccgcgatg tattgtagtt cgtaaagaac aaaattaggg
    34501 atcatcaagg ttccttctaa gaatccagtc tttgtaatat cataaatccg accgtcaatg
    34561 atcacgcttg tatccaagat tttatattta tggaaatttt ctcctgattt tcgttctaac
    34621 agttgactct caacttgact agctgtttct tgctcgattt ttttgcttcg tgaaccaaaa
    34681 actttcttcc attcttcgat tcgtgtcgtt cccattctca atcccagata gcctaagatg
    34741 atcatcagta aaatcggcaa tacactattg acgaatggaa tttccatatt gtaaagaggg
    34801 gtcgagatca caacacctaa agtcaatccg atgatcgcac cgatcgcacc gaagagaaga
    34861 taagtcaagc tgacctcact tagtttttgt tctacttgtt tgataatagc tgagatatgt
    34921 ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc ctaacaggct gttggtaaat
    34981 gtattattca gccatccgtt tgactgttga ccgattgcct gccaagctga gggtaaaaat
    35041 gaaataccca agcttgcgcc gacaatgatc atcagcaaag taatgacacg tttttgcatc
    35101 gtttttcctc cgtttcgaca atcatttatt agttagcgga acacacgctt caacgtttca
    35161 gccaaagttg ctactccaac tatctcgatt ccttttggcg cttcccagtt acctaagttg
    35221 tttttaggta ggtatacttt tgtgaagccg agtttttgga cttctttgac tcgttgttca
    35281 atatgactga cacgtctgat ttctccagtc agtccaattt caccgatgaa acattccgtt
    35341 ggctgtgttc ctttttcttt atagcttgaa gcaatactga cagcgatagc taaatcaatc
    35401 gctggttcat ttaattttac cccacctgca gcttttaagt aagcatcttg attctgaaga
    35461 agcaacccag ctcttttttc cagcactgcc atgatcagag atacccgatt gaaatcaaga
    35521 cctgttgttg ttcgtttggc atttccgaac atagtaggtg tgactaatgc ttggatctct
    35581 accaaaattg gacgtgtccc ttccattgcc acaacgatag cagagccagt tgcaccgtct
    35641 aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt cttccaatcc atgctcatgc
    35701 atttcaaaaa tcccaatctc attcgttgag ccaaatcggt tttttactgc tcgcaaaatc
    35761 cgaaaactat gatgttgttc accttcaaaa tataacaccg tatccaccat atgttctaac
    35821 attcttgggc cggcgatcga gccttctttg gtaacatgac cgacgataaa aatggctatc
    35881 ccatttgttt tagcgatttt gagtagttct gcagtggttt ctcttacttg gctgacactt
    35941 cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga tggaatcaat gataacataa
    36001 tcaggggaga tatgttcgat ggcacgactg atttcgttca tatctgtttc agcgtataga
    36061 taaaattctg tgttgatact tccgaggcgt tccgcgcgta attttatctg ctctgcgctt
    36121 tcttcgccgg atacatataa gacttttccg cctatggctg ctaattgctg agaaacttgt
    36181 aacagcaaag tggatttccc gatacctgga tcgccaccaa tcaagaccat agaccctggc
    36241 accacacctc cgcctaacac acggttcagt tcttctaatt ttgttttgat ccgaggttct
    36301 tttttaggga cgacgtctgc gatttttgtt ggttttgctt tttctcctgt caaacttgtc
    36361 cgagttctgc ggtccgttgt atcttgttcg atttcttcga ccatcgtatt ccattttccg
    36421 caatttgggc agcgtcccaa gaacttaggc gacacatacc cgcaattttg gcaaacaaat
    36481 tgtacttttg atttttttgc cattgtaccg cctcctttta tcctaatcat gagacattaa
    36541 atcaagctta agtatcttta acgttttatt tactggaaga accaaatccg ccttgacgtt
    36601 gagcagtcgt ttgatcttga tctgctttta aaaacggcaa aaagatccct tggccgatac
    36661 gctcgccttt tttgatcact acatccttga aaccaaagtt ggtgaattgg aacatgatat
    36721 ggccttcatt tgcctcatta ttgtaataat cactgtcaat cacacctact ccgtttgtca
    36781 acactaaaaa ccgcttcaac ggattgcttg aacggttagc aagctgcaaa aattcatctt
    36841 ctcccatgta agctttgatt ccagtaggca cgagggttgg tttcaattgt ttttcatttt
    36901 ctgatacatc ttttttcaat ccatctgcga ctgtttccaa cccctttttc cagcctgctt
    36961 tccagatact tggaatcacg acctcttctg ctgcttcaaa atcatagcca gcagcatgat
    37021 gtgtagcgcg ctgcggtaga ttgatatttt gatctttata tttagaaata acttcaaatc
    37081 ctctttttct caccggtttt cctccctaaa taaactactc ctattctaac atatccgagg
    37141 ctgtaaaaga ctttctttac aaattcttca agaaattctg ctatcttaaa gtaaaccatt
    37201 aattcgttct ttttccaaac gactgcaagt tgtacaaaaa aactattttt tacatgactt
    37261 tactcgtcaa aacaagtaga atagaacgaa attaatgagt ggatatttga ttgaggtgtc
    37321 acatgcgtaa agaaattaaa aatgcaaaac gaattattgt caaagtagga acaagtacat
    37381 tgatttatcc caatggaaat atcaatcttg cggcaatcga tcagttagct tttgtccttt
    37441 ctgatcttag aaatcgggga aaggaagtga tcttagtctc atcaggagct gtaggcgttg
    37501 gtatgcataa attacatttg tcagaacgtc cgactttgat tcctgaacag caagctgcgg
    37561 cggctgttgg tcaagccgaa ctgatgaata tctataatca aagattcagt gtatataatc
    37621 aacagacggc acagatcctc gtgacaagag acgtggtaga ttatcctgaa agtcgtaaaa
    37681 atgtgaggaa tacattggaa cagcttttga ttatggacac gatccctatc gtgaacgaaa
    37741 acgatactgt agcagtggat gaattagatc atctgacaaa atttggcgat aatgatcagc
    37801 tgtcagccat catggcaaaa cttgtcgcgg cagacctttt gatcgtcctt tctgatatcg
    37861 acgggtttta ttcagataat ccgactacaa atcccgaggc tcagatgtat cgctatatcg
    37921 ataaaatcga tgaaaagatt ctggcacaag caggtggtgc tggtagcaca tttggaacag
    37981 gcggtatgca gagtaaatta aaagccgctt ctaggatatt tgaagcaaac agcgcaatga
    38041 ttttagcaaa tggaaaaaat ccggcaatta tttttgatat tcttgcagga aaagaagtag
    38101 gtactttatt taaggaggac ttgaaatgac tgacttgatg caattaggac aacaggcaaa
    38161 agatagcgcg caacaactag cacttatgcc tacaaaccgc aaaaatgagc tacttgttca
    38221 aatggcacaa accatcaaaa agaatcaaca agcgatcatt gaagcaaatc ataaagactt
    38281 agaaaaagca gtcgaaaaca atatcagtga aacgatgcaa gaccgcttgc agctgacacc
    38341 tgagcgaatc aatgccatgg ctacagagat cgaaaaaatt gcttcgttag acgatcctat
    38401 tggaaaagta gatgagatgt ggacgaacac cgacggattg agaatcggca aaaagcgcgt
    38461 gccactaggc gtgaccggca tcatttacga atctcgtcca aatgtcacga cagatgcagc
    38521 tagtctagca ttcaaatcag ggaatgccgt tatccttcgc ggtggcaaag aagcattctt
    38581 ctcgaatcaa ttattagtcc aattattgca gcaagtactg gtcagtgctg gcgaatctcc
    38641 ttatgccatc cagtttgtcg atgatacttc tcatgaaact gcaggacagt tgatgcgatt
    38701 gacagaatac ttagatgtgc tgattcctcg aggcggagca aaattaatcc aacgagtcaa
    38761 agaacaggca acggtaccta tcattgaaac aggtacagga aataatcacg tatatatcga
    38821 taaagaagca cagttatcta tggcagtgaa catcatcgtc aatgcaaaag cttcccgtcc
    38881 atctgtctgt aacgcggcag aaacattgct gatccattct gagatcgcac cttttttctt
    38941 gccagctatt gaaaaagaac tggtagaaca cggggtctct ttacgtgcgg atgctcgtgc
    39001 gttagaatat ctagagacgg ctgctttagc agaagacaca gattgggata ctgaatatct
    39061 agattatatc cttgctgtca aagtggtcga ttctttggat gaagcaattg cacatatcaa
    39121 tcggcataat actaaacatt cagaaacgat cgtgacagat agttatgcgg ctagtcaacg
    39181 tttcttaaat gaagtggacg cggcggctgt ctatgtcaat gcctccactc gttttacaga
    39241 cggatcggta tttggttttg gtgcagagat tggtatctct actcaaaagt tgcatgcccg
    39301 tggtccaatg gggttaaatg aattaacttc cacaaaatat atcatttatg gcgatggaca
    39361 aatccgcgaa taatgtttcg tgtgaaacat tattcccgcc ttttgccttt tttctgtaaa
    39421 ggttctatcc aactagaaag gtgtcaatat gtttgaaatt ttaatgattt tttttattta
    39481 ccttatttct ctgaatatcg ctgcttttct gggagtcggt attttatccc ttttctttca
    39541 attcaaaaaa cgaagcatag ggagtcaacg ggaaaaatgg tcgcagtatt ttgacaaaat
    39601 cgggcaaaaa gggctggtta cacgcttgca cattagttac atggttgcat tatgcttatt
    39661 agcgacaatc aattactatt cttttttcga tcattcaatc gcttatacga ttacgctact
    39721 gattgctggg atttttcact tatcttataa atatcagctg aataaaaacc acttgaatcg
    39781 gactttccgc taaaaaatat ccgtacgata agtagagtgc cttgaagatc ggcaaaaaac
    39841 tgccggactt tttagaggct gtgacaaaga ttttgtcaca gcctcttttt ccatataaac
    39901 ggcgttcgcc taccagctgc ctggtaaatc tgtttcctct tcgttaagaa gcgaaaatcc
    39961 gtcaaatgtt tcgccatcat aataacgaag cagctcatcc atggacaagt tcatcgtttt
    40021 ttctttttct tcttccgctg attcagccag tagctgttcc cgatacacct gatacatacc
    40081 agctattttt tgctgcatcg cttttctagt ttcaccttcc gcattgatta ttggcaattc
    40141 tttgatatag ccacgataaa tcaaccgatc atctgaaaat tcaatgggta attcaacgag
    40201 tgtcaacccg acttcctgaa aatattcttc cagcatctat tatcccccca ttctttttct
    40261 taaatgaatt ttagcttacc tactgaaaat tttccagttt cattattttg agaaaaaaag
    40321 ggaatgtgac aaaaatcgtg tcacatcccc tttttccgaa taaatggtgt tcttctgcca
    40381 actcctcaat cataagtcac aatattcaac aaacatgaga aactgttttt tgaaattgtt
    40441 ccttgtgatt cagagttaaa cgacagtctc acaacctctt ggtaaacggc gttcaaaagc
    40501 ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc
    40561 tgttcttatg acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc
    40621 atttgtagca aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc
    40681 acctgcaaaa taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa
    40741 tggtgctaaa gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg
    40801 ttgcagacct ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa
    40861 aaatcctgct aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa
    40921 taacagcaaa caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa
    40981 cttccgctca agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc
    41041 aaaaaataca aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc
    41101 aagtaaagta aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt
    41161 atgattgctt aacgctttga caccttccca aaggcctact tttctctttg gtttctcagt
    41221 ttcaggtaaa agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa
    41281 aaatggataa cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat
    41341 tccgcagcca agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat
    41401 actgacgatc gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc
    41461 acgtaaccca atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac
    41521 gatgataaac aatcctgtca tcaatgtttt ttcaaaccga tccgactaga taagaaacct
    41581 gtaaatagca tcaccacacc agtgactaac atgtaactag taaataacag ggtcgtttca
    41641 gctggcgtag cgtttaactg tgcagcaatc gtttttaaga ttgggtctac tagacccact
    41701 cccataaaag cgatcataca ggtagctgct acaactagcg ctgaactttt cccctttgtt
    41761 tcttcatttg tttgttcttg tatatctatt tgattctcca atatttccat ccctttctct
    41821 ctattagcat catacatgat ttattttaca tgtaaatatg cacatgtaaa acgtggaaac
    41881 tttactgtga tataataaag aaaataagac gagaggtagg atttttatga atactttagc
    41941 ctatatatta ttatgcgtgc ttttatccaa accacgttct gggtatgaat tgaagcagct
    42001 gatcacaatt ttttgggaag cccatcacag tcagatctat acaacgcttg ccaagttaga
    42061 ccagcagggt tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa agatctacca
    42121 cttgactgat gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa ctcccgctcc
    42181 tacgcaaaaa gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg ataaaacaac
    42241 agctactgga ctgctattca ctagagaaca acagctgaac aaaatcatgc aaaaaaatca
    42301 aaaaaaattg aatgacctct cgctagacaa gaaacaagaa tttggacgtt atgttgtgat
    42361 ccagcgcaga attatgcttt gtcagcagga actccaatgg tgtcagcaag taagagaaca
    42421 aatgcagcag ttttttgagt aagggataaa cagaaccttt ctagaaatat ctattgaaga
    42481 gcaaattatc ttcaataaaa gagcaataca gttggaaaag aaaaagcgat ccgaacgaca
    42541 ggccaaaacc tatcgttcgg atcactattt ttctagaact gcattcaaga gactatgaca
    42601 aaaagcatgc caaggccttt tttcaaataa cagtgttcca tcattcatta ctttgaattg
    42661 cttttagcac acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt aaagcggcaa
    42721 tcacattcat tttccaagca ttcatataag cagagaataa ttgatcaggt attccttgtt
    42781 ccatgatcac accgaataaa gacatacatg tcaccattcc taaaaccatc aagcatgaaa
    42841 tagttaagat catttggacc ttgctttctg gatttactgg tagtttaaag gcaatttttt
    42901 tcgccagcac accgatgatg aagacatcca aaatgaaagc caccacgaat ccaggcacta
    42961 gaccaatcaa caaacttgat aaatgaagat cttgatgcag ccataaatta tacgcgctca
    43021 tccccaagac catcaaaaaa cacatcattg ttgtaaaaat tattccttct tttttatttg
    43081 taggcaatct gtaccactcc tttaaatttg tcacgaaaat catcgtagca catttaaaaa
    43141 tttctcgtaa gtactttttt tattttctgc ccttttattt cataaacttc atcagccgta
    43201 cgctcgacaa agtaagaatc atgagaagta aacaaaatcg ttcccggata tatttgcatt
    43261 agcttctcta aagcttcgat cgttgccata tcaataaaat tagtcggttc atctaacagc
    43321 aacacattac ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc ttctccccca
    43381 cttaatgtac ataacggttt cgtcaaagtt tcctgagcaa accctaagtg attcagcaaa
    43441 ctacggacaa gcgattctga aaactctgtt tgtctcatga caaaacgaat gatggattct
    43501 tcagatgtca tttgataacc cttttgctga tatacttgaa agcttacttt cggagagaga
    43561 aggattcctt ctccttgttt gcggatatgt tctaataagg ttgtcttacc tgaaccattt
    43621 tcaccgacaa tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt taccagtaat
    43681 gttctcccac ttctttccaa ttggacattt tgtcccatga tgggatagcg gctgtggagt
    43741 tcaagagatt ttggtactgg aaaacggatt tgtttcatct gctgcggctt ggttgtttct
    43801 cctatttttt ggagtcttct ctctaatgtt ttcgcattct tttggatggc tttttgtaca
    43861 ctgtcttttt gtttagagga agacaaccga tccggtctga tttgttgctt tttcttttta
    43921 ctggacactt tttccaactt ttccgcttgt tttttctttt cttggatcga tttttccaat
    43981 cgttttttct ctttcatgat cgactctgct tctcgtagct gagtcttttt ctccaattcc
    44041 ttttgagtga gataggcact ataattcccc gaaaactctc ggatttctcc gtcttttact
    44101 tcccagattt tcgatgctag ctcatctaga aaatagcgat catgactaac aaaaaccagc
    44161 gtaccataat aataacgaag ctcttcaatc agtcgatcaa tactttttct atctagatgg
    44221 gttgttggct cgtctagaag catcccttgt tcataagaag aaagaagacg tatcaactcg
    44281 atctttcgtt cttcccctcc gctccatttc cgctctgaag tttcttccag tcttaactgg
    44341 aaatgactgg ctaattccaa atttaggtcc tttgcttcag cgagataggt taattgaggc
    44401 aggtagttga aggtgatctc tgtttggatt ttcccatgat cgggaaaaag ttcaccggct
    44461 attagtttga gcaaagtcga tttaccgaca ccattttctc ctatgatccc tatacgatct
    44521 tgctgataga cacgaagaga atcaatagat agttctagct ggttgccaaa gctgacttgt
    44581 agatttgtta tatttactgc taaattttcc atatgtttta cactcctatt tcatgtaaaa
    44641 caacaattat cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa ctgcatcaca
    44701 tcttttccta ctctgaacga aataactatg actaaatcac caaatctgtc atagctttca
    44761 cctattctac tgtcgttcga aaaaatggac atactccatc catgaaattg ttgtttatac
    44821 atgtcttttg aatttattta gttgttattc aaaagttcga aacgtaattt catcgatgca
    44881 gtcatttttc cgacctcctt ttttattagg ttaccacaca cgattcaaaa aaagcaatag
    44941 ctactgaata gtaactgaaa accttttatt cgaacgtagt gatcttttct ggtgctaaac
    45001 gaacagactc gtaaccttct tctaccgctt ttcctattga taaaataata actggaacat
    45061 aacggtcttt atccaaacca aatgcctctg ccaactgatc tgcttcgaat ccaccaattg
    45121 gatttgtttc atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc gctaagctag
    45181 aatcgacttt gactacatcg ttcatttctt ctcttgaaaa actcttgtaa taaggaatga
    45241 tcgcagctaa ttgttgatct ctgacttctt ttggcatctt ccctgattcg taagcttggt
    45301 tatagatttc ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg accattgcag
    45361 aagaagtatc attttgtctc gtattgaaac ggatcaaagg acgcaagatt tcttttgctt
    45421 cctcgctttc agcgaccaca aagcgccatg gttgcatatt gacagaagaa ggtgcagtcg
    45481 tcgcttcttt gatcatttcc agcatttctt cgtgtgggat tttgtatgtt tcatcatata
    45541 cgcgaacgga tcttctacca gtcataattg ttgaaaaatc atttttttgt tccattatta
    45601 ttaacctctt tcgtttctgt tgttatattg caaagttggg tattcaattt atctaaaagt
    45661 gttagaaatt gtttcatttc tacatcgctg aaagccgggg atagcacgga acctgtatct
    45721 ttatggtcca tttcacaatg ctcgattttc ttctgggctt tttctgttag cgctacatac
    45781 acttcccggt tgttctgagg atttctctga cgcgaaacat agccatttgc ttccaatacc
    45841 ttcagatgac gagtaactgc tccttgatca atctgcaact tttcttgcaa actgctttgt
    45901 agcaatggat tttcttcttt cagtctcatc atgatctcgt atctagtaag acttataccg
    45961 atattttctt caaagatctg gacgattttt tgatcggcta atttgatttg atataaaagg
    46021 tgactaatct cttctaaaga cataatttcc tcctttctaa taattgactc gtcaacgatt
    46081 gacttgtcaa taatagaata aaaaaagaaa aaagtcaaag aatcagctgt gtaataaaaa
    46141 aaacgctctc aatagaaaag tatagagaaa agaaattttt tgtagaatga acggaaaaaa
    46201 tgataaagaa agcacaacgc taaaaccaag attattgatt cttatcaaac tatagaagat
    46261 agctcttctg cagtagaaaa ttttacaccg ccaaaaattt ccgaaatcgc cttttgcaag
    46321 aatcccgtcg aatattagaa attggatcag tatgcttaaa cagtaataaa aaagttatga
    46381 caagatgttg tcacaacctt ttttgagtaa acggtgttca aaaacttgca tctgcggtaa
    46441 taagttcaac caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc ttactacttg
    46501 atgcagggca gctttttcac tacctctttt taataaccat aaaatcctat tccttcatat
    46561 ctccagccca tcggtgttag ccaatctctt tccttagcac tcaaggtata gtgatgggta
    46621 ccagtttttt catttggatt aaatagtcga taaattggct tggaaccacc agaataaaaa
    46681 cttagacctt cataacgcca accgattttt gttaaagagt tgatctcaga ttgtgccatt
    46741 gtgtaatgat ggtctccact gtaaggattg tataaacggt agacaggttg tccgctgttt
    46801 ggtgcttgcc aagcaatccc ttcatattcc cagcctacag ttggcagata atttttttct
    46861 ccggcattca atgtatataa atgttctcct gtatgacggt tatacagacg atacatcgga
    46921 gaagttgaag ttggtgctgt atcatactgt gtcagattat aggtttcgat tacattgttc
    46981 aatgtagaac cataattagg cgcagtggca taacgacctg ttagccaagc cgtagcatct
    47041 ttgtaagagt tcgtattgct tttccatgca ccggaatagt agtaaacgcc tggctgaaaa
    47101 gaagtcgtct tcaataccgt tacgttatct tgcaatgatt ctttgtacga aggatatttt
    47161 ctaaaagcgg cattcaccgt aatccattgc ccattcacat attccgaagt aggcatcgta
    47221 acagattggc cattatagct tcctttaatc ccaaatagat tgtaattagg ggcagaagcc
    47281 aaagtactgt tcccccagcc actttcaacg atggcttgag caatcatgac tgatgcatat
    47341 aagtcattgg cacttgccaa actttgtgca gttgaggcaa tactatcaat gaacgcttgt
    47401 tgagaattag cagatgagcg agcataaaaa gcatagccag tatagttttc gaattcagac
    47461 aaatctgctt gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt cgtgatttct
    47521 tctgcattct ctggattgtt ctgagcttct gctgatgtac tgtcttcggt ttgtgtttgt
    47581 tctgttgttt cagttgttgg ttcttcggtt gaaattgtat tttctgagac agtagctgac
    47641 tgcaaagtac tctctgtatc gttttcaatt cctgtttctg aagaactcga tgtctgagtt
    47701 gcgacagttt ctgtcgattc ttcagctagc actgttgtgt tggcaactgc tagatttcct
    47761 aaaagaataa cgctaaataa taaattcttt gctttcatct tttttctcct ttgaattatg
    47821 aaacttttcc taaataacag tgtaactaaa aaagtaaaag caagtcaatg tccatattta
    47881 aataacattt gtttcttttt gataaatttg ctttttctac ataaaaagac gtaaatgaag
    47941 aatattcttc tccattcacg ccttaaattg atggtcgttt gaataactat ttaacaagta
    48001 attctctttg gatattatcc gttatggatt atacttcctg tgtcgtcgga cggataatca
    48061 tgttactgac agacatccgg tctggcgttt ctatcgcaaa tgctacagca gaagctatat
    48121 cttcggaggt caatccccat tctttttgcg cttcatgaag ttcaagagca gcctttttgt
    48181 cgctgatggt ttgatataat tcagtttgaa cagctcctgg agagatgatc gtagatttga
    48241 tgttattttg ccgttgctct tgacgtaatc cttccatgat tgcacggaca gcaaattttg
    48301 ttccgcaata aacggcggaa tcaggataaa caacatgtcc cgccacagaa tcagttgaaa
    48361 tgatatgccc agatttttgt ttttccatga ttggaagtac ggcggaaatt ccatttaaca
    48421 cacccatgat gttgatatca agcatatttt gccattcatc acggtgacct tcaactaatg
    48481 gagcggttgg catgattcct gcattattgt acaatacatc gattcgaccg aacttttcca
    48541 tcgctaaatc gataactgct tggacttgtg caaaatctct tacatctgct gtttgaatat
    48601 atagctcagc ttctggtaaa gattctttta ttgcttttag gcgatcttct cggcgtgcag
    48661 ctataactag tttagcccct ttttctgcta atagcttcgt tgttgcttca ccgattccgc
    48721 ttgaagcgcc catgatgaca atcacttttt ctgataaatc attcattcta ttctcctcct
    48781 gttttgaaaa atctcttgct tatactcact atctcttatt tcatcttact gttcaaataa
    48841 tccgttcgac aggtttgacg attttggcag ggattcctgc aacgatggta ttgtctggga
    48901 catctttcgt aacagttgca ttcgctgcaa caatggcatt ctcgccaatc gttacgcctg
    48961 gcagaatagt tgctcctgct ccgatccaag catttttctt gatgtggatt ggctttactg
    49021 acaagcctct tcgttctttt ggatcggtta gatggttcac cgtgatgagg ttgacacgag
    49081 gaccaatcaa tactgaatct tctaaacaga tgccacctaa gtcaacgaac atcacttgac
    49141 gattgataaa gacatttttc cctatactaa tatgtttgcc gaaatctgta taaaaaggca
    49201 gcagaacagt caccgtatca tctactttgt cactaatgat attttctagc cgtttgcgga
    49261 tatctgctgg ttcatggtac ccagtattca gcgctgctaa aggctcttcg ttttcagctt
    49321 ggatctgatg gatcacttca aagagcggat ccgttactcg aatctcttta ttgacgattt
    49381 gtttttcgat gaggcttgtc attttgctcc ctccttttat ccttacttta taacggacgg
    49441 cttatcatgt ctaatactta taaaacatac ttaactattc cttttaacta tacttagtgg
    49501 tatgcttttt taaaaacagg agggaaaaaa tggatattcg tatactgacg tattttttag
    49561 cagtagctag agaaaaaaat atcagccgag cagcaaaatc tctgcatatc acgcaaccta
    49621 ctctctcaaa acaactgaaa gatttagaag aagaacttgg tgtgacactt ttcactcggg
    49681 gctcccgaga gatacagttg acggattctg gtcgatatct ttattcaaaa ggaaaagaaa
    49741 tcttgtcgtt ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc atctctggag
    49801 aaatctacat tggcggaggc gaaactaaag caatctcttt catttctgat agccttcatt
    49861 cgttgatcaa ggcgcatcct gatatccagt ttcatttata tagcgggaat gcagatgata
    49921 tcatagacaa actggatagc ggattacttg attttggact cgtaatcgaa ccgacaaaca
    49981 aacaaaaata ccagtcattt cgactgccag cccaagatcg ttggggactt ttgatacatc
    50041 gaaatcatcc tttagcaaag caaaccgtca tccatccgca ggaactgaaa actgttcctt
    50101 tgatcatttc ccggcaaacg tcagtggaca gtcaactagc tgaatggcta ggtttcagca
    50161 tagatcagtt atcgatcgtc ggaacatata acttattgta caatgcttct ttgatggtcg
    50221 ataacgggac ttttggtgca ttagctctag atgggatcat caatacttat gggacggaaa
    50281 aaatattcat cccactcgat ccgccattac aagcttcact gaatctcatt tggaaaaaag
    50341 accagcctct ttctcctgct gctcgtaaat ttttagatgt cctaacggag aaatacagtt
    50401 aagtagagtt tttttccttc gctttcagct ttttaacaac gaataagata agcaaaagat
    50461 ccaacgatta aataacataa gtttcttaat ttatttcttc cttttatttc tgataattcc
    50521 agtaaattac tataattata aaaaaagaat tgacaaaaca taactgtcta tataaaattg
    50581 attacgttaa caataattcg tttcatgtga ctagatcata ctaggcatga aaaatctctg
    50641 aggaacatgg tttccctagg aggtttttcg tgtctatttt tgtttggccg caatcaactg
    50701 gtctagcaaa cgtgaaaacc aaatcttcaa aaagggtgcg cgcatgaaaa tcaaaaagat
    50761 ctttaatcaa aatgcagtat tggtagatga cggtggacag gaaaaagtag ctattggaaa
    50821 agggattgga tttgacagaa aaagaaatga tttgattttt gatcgtgatg tcgaacggat
    50881 atttgtcatg gaaccagaag gtcaaatcaa gttgcaaaat ttacttaatc agattgatga
    50941 acgcttttta tttgcagcag aaacgatcat tgatcatgcg gaaactgttt tgatggaaaa
    51001 gttgaatgaa catgtattga tcgctttgac cgaccacatt gctttttctg cggagaacat
    51061 taataacggt atcgtcatcc gcaacaaact tttaagagaa atcgaagtgc tttacagtga
    51121 tgaattcagt attgctcaat gggcagtaga gtatctgaca aaagagcttg ggattccata
    51181 tacttatgac gaagcaggat atatcgcaat ccatattcac agcggacgaa gcggtcggaa
    51241 caataaccat cgcagtatcc gtgaagtgac gattgtatct gacatcatcc atttagtgga
    51301 atcagaattg gaaacagata tccattcaga accattttca ctgaattatt caagactggt
    51361 gaatcattta cgactgcttc tacaacgaac ccatgcgcaa caatatgctg ttttagacac
    51421 ggaaatcgta gaaatggtca aacgaaaata cccagaaagc tataagattt ctaaaaaaat
    51481 ccgtgtgttg ctgaccaaag aataccagct cgcgatcacg aaagaagaac tgggttactt
    51541 ggccatccat atcgagcgtt taagaagcgc aatcgtacaa acaaatgtta acaatcatga
    51601 ggaggaaaaa aattgaaagc atatctacaa cgaatgggac gttcccttca acttccagtt
    51661 gcggtcttac ctgctgctgc tttactagta gggatcggaa actggtgggc atcttatagt
    51721 aacgacattg tcgctcattt tttacaagct ggcggtaacg cagttttagg tcaattacct
    51781 ttgctgtttg ccgttgggtt agcactaggg atgtcagtgg acaaatcagg tgctgctgcc
    51841 ttggcaggtt tggtcgcatt tgaagttcca gtaaatgttt taaaaactga ttcagtagct
    51901 actttattga atatcaaacc agaatcagtt gatccatctt ttgctcagat cagtaacgta
    51961 tttattggta ttattgccgg attgattgcg gcagctcttt ataatcgttt ccacgaagca
    52021 aaattaccga tggctttatc tttctttagc ggcaagcgtc tagtgccaat cttggctgcc
    52081 tttgtcatgt tgctgatcag tgcagtgcta ctgctcgtat ggcctccggt ttactctgct
    52141 ttagtttctt ttgctaaatt cattttgagt ttaggctggg gtggtgcagg tctttatggc
    52201 ttcttcaacc gtttactgat ccctacagga ttgcatcaag caatgaactc cgtgttctgg
    52261 tttgacgtag caggaatcaa tgatattggt aaatttttgg cttctgaagg aacaaaaggc
    52321 gtaacaggaa tgtatcaagc tggatttttc ccaatcatga tgttcgggct tccagcagga
    52381 gcatatgcta tttacagaaa tgcacgtcca gaaaacaaag caaaaacagc ttccttgatg
    52441 ctagcagcag cttttgcttc attctttact ggtgtgacag aaccacttga attttcattt
    52501 atgttcgttg cttggccatt atatgtcttg catgcaattt tcactgggat ttctttagca
    52561 gtgagtgcat tcttccattg gacagcagga tttgccttta gtgccggatt tgtcgattac
    52621 ttcctatctt tgaaaaatcc gattgcgaat cagccattga tgttgatcgt ccaaggatta
    52681 gtaacagcag tgatttacta ctttggcttt aactttgcta tcaaaaaatt ccatctgatg
    52741 actcctggcc gcgaggaagc agatctttca gatgacgata ctgcaacgac taattcagac
    52801 aataaatatg cggcacaagc aagcaaaatc tacgctgcat taggcggagc cgacaatgta
    52861 acttcgatcg ataactgtac tacacgcctt cgtttgcaag tcaaagatac aggcctgatc
    52921 gatcaaaata aaatcaaagc cactggcgta cctggtatga agatcatcga cggaaaaaat
    52981 gcgcaagtca tcgtaggtac agaagtacaa ttcgttgcag atgagatggc aaaactacat
    53041 ggtggtgctg cagcacgacc tgcacaaaca aacaccgtgg ttaaaacaga aacatttgcc
    53101 ggtgaaacga tcgaacaaga tatttacgct atcgcaaatg ggaaactgat tccaatcact
    53161 gaagtttcag atgatgtatt cgcggaaaaa atgatgggtg acggctatgc tgtattacca
    53221 gaaaatggag aaatcttctc tccaatcgct ggtacgatca caaacatttt cccaacgaaa
    53281 catgctgtcg gaatccaaac agatgctggt atcgaagtct tgcttcatat gggcatcaac
    53341 actgttgact taaaaggcga accattcact ttatatgtag aagaaggtca aaaagtcgca
    53401 agaggtcaat tgattgcttt agttgatctt gccgctattc aatctgcagg caaaaacacg
    53461 gatatggtcg ttgtattcac aaatggcgac aaagtccaaa gcttagaaat cgaacccgca
    53521 cgtgatgtaa aagcaaatga taaaatcggc tctgtttcca acaaagcctg agccatcgtc
    53581 ttccccagac ttttttatcg ataaacaaac aggagcttag acaaaaatct tgtctcagct
    53641 cctttttccg aataaaaacg gcgttctcct gccaactccg cggtaataag tccagctaaa
    53701 cgaaacatat gaagagctat tttttatttg actcttctta ttacttgatg cagaacagct
    53761 ttttcacaaa atttttcttc atactcaaaa ctaatcggct ttttcacaac ctctttatac
    53821 attattcctg atccaatatt tcttttaatg ctgcttcaag agaagttaat ggttttccca
    53881 atactttttc taaatcatca gaggaaatag ctaactgatc ctttttaata tcatgttgga
    53941 tcgctaaaaa catgtcagct gcttcttgag ggaatccggc ttcttttaga ttttcgacaa
    54001 acgctgcatc acttgcttca ataatttcta actctttacc tgtcgcacgc tctaatgcct
    54061 tggctaattc ttcatagtca gttagattgc cggataattc taagatttct ggagagtcac
    54121 tttctactag tacttttgct gcagcttctg catattcacg tttcaatgcc caacctgttt
    54181 ttccatttcc tgcagcataa acgaattgac cagtttttaa agcctgccca atgataggta
    54241 attcattctc tacataccaa ttattccgta aaaatgtatg ggaaatacct gaatccttaa
    54301 tcattttttc agtgaattgg tgatctggcg ctaatacact gatcgagtga tcggcatctg
    54361 caaaacttgt ataagcgata taagataccc cagctgcttg tgctgccttc actacattct
    54421 tatgttcggc ttgacgattt cctggaacgc cagagacaaa aagcaatcga tctattcctt
    54481 tcaacgcttc tttcattgag tctaaatcat cataatcacc aatacgtata ttaaatccag
    54541 cttctttcag tgcttctcct ttttcttcac tacgtactag tacatagatt tcattttgtg
    54601 gaaccatctt ttttaagaat tccagcgcat aaccaccaaa acctccagtt gctcctgtta
    54661 ctaaataatg catatttgcc actccctatt ctttttattt gttaagattt acagctgtac
    54721 atttataaat tacaccttta tcataaagag tgtggtaaga taagtcaagc aaaaaaaatg
    54781 aaaggatgac aactgatgaa gtattctctg caatttagtg atgcaatcca tgtacttgcc
    54841 tatattgaaa tgtttcaaga tacccgatca ctttctagtg agatgattgc cagtagtatc
    54901 gaaacaaatg cagcaaatgt acgtaaaatc atgagtcagc tcaaaaaatc cggtttgatc
    54961 tttacaaaaa ccggaaaacc gcagccttcc cttgccaaaa gtccagatca gatttcttta
    55021 ctagatgtct atcgcagcat cgaaggtaat acacagctta tccaagtcga tccaaaaaca
    55081 aatccaaatt gcgtcgttgg tgcgaatatc caagaagctt tagaagaaag ctacgctcgg
    55141 ctgcagaaaa aggcagaaga agaaatggct aagatcacac ttgatagtct gatacataaa
    55201 atagccgttt tggaaaaaga aaaaagacca gaaaacacag gcctcgtaga gagattttta
    55261 taattctctc tactgtgcct gcatttttct gatcggaatc gtctacataa attcttttat
    55321 tctccggggg acaaaagcct tgtcatgccc ctttttcctc tctaatgctc aggtcaaagc
    55381 gctgaagtca tgacgtcttg ataaacggtg ttcaagtagc tgaccctcgg cattagttct
    55441 gaaaaatgca aaatatggaa agctatttcc catttttcct ctctaatgct caggtcaaag
    55501 cgctactttc acgacctcta tattatcatg gtttattgac taccggtatc cagatttctc
    55561 ccatatattt cccgttggta actcccattt cgactacagc atttggaccc ccaacatagg
    55621 cgtaatcttc tacttctctt aaaacatgcc caaaggccgt attcgtcaaa tcatttctta
    55681 attcttcagg cgattctgct aaagcgctta caacaagata cgttcctttt gggaatggga
    55741 tgattcgcgt agtgtttgga acatcctgac tcgtttgaac accgacatag tacatcattt
    55801 tcccgttata gggttcgttg actgtaaaga aataatgatt ttcagcagct tgtttcaatg
    55861 catctattgt tccattaccg ataacttttt gctcaaatgc ttgtttctct gcagccaaac
    55921 cgacaaaatc cgtattgcta ctcttcaatt ccacaccaat acccgtcacc gtaaaatctg
    55981 gtttttcttc gatcctatac tttgccattt ctcccaccct ttctattata ttaagttcat
    56041 cttacataaa attaaaggga aatgacacga ttacgctctt ttttctaggg atatttttat
    56101 tttttaacta tttttttgct ttcactgcaa tccaaatctc actgtaaaca ttactgaaat
    56161 cctctcccca ttttgtaaaa gagatctcgg gagcttcgac taacccataa tctgaagaag
    56221 gaagccattc tgcatagatt ttcccccaag tatcttgtaa agtttgggga aatggccctt
    56281 tattaggaaa aatggcccaa gtgtgttctt ctatagcaag catttctaaa tcagcgtacg
    56341 gattttcttt tgtcgtagca aagccaatca tgtgcatcaa actgcccttt tcttccaagc
    56401 ggtctccatc aaatccataa gaaacgttga ttacttgatt tggatataaa tctcctaact
    56461 tatgcatctc ttccctttga gtctccgtga tcgtctgcgc taacttttgt atttcttgat
    56521 tgactccttc aaatttgaca ggaacttttt tcgccacacc tgccacataa aactgttctt
    56581 tcttttcgat acgaaattcc atcgattttc ctcctctgac atcaataaaa aatgtcaagc
    56641 gtggaaaaga tttttgtatg ccgtatctac tgatttctga aggcagatat cctgaccaat
    56701 cacgaaaagc tcttgaaaaa ccttcgactg tttcatatcc atatctaaac gccgtttctg
    56761 tcactcttga tccatctaga agatcgcgat tagccaaagc caatctacgg tttttgatat
    56821 agtccattag cgacatccct gcaataaacg taaagatgcg ttttaattga tattcagaga
    56881 ttcctgtatt ttcggctatt attttatagg aaagtccttc tgtcaaatgt tcttcgatgt
    56941 aatcgatcaa ttggttcaga tctttaagca tatttatctt cctccttgat tgccttttta
    57001 tcatattatc aaagaaagtc aattacttga tgaatcagga accaatttag tcagatgtag
    57061 aaaatgttgt atggatctaa agaaaattct caagcagcgt ttcgtaacgg ataattggta
    57121 ttatctgcct atctatgttt tacctttaga aaaataaatt ttggggaaga cagattctaa
    57181 gtaaacaaag cggtaaaaat atcttttatt cccttagtta atccgcttac tacctactgt
    57241 acaaagcaaa ttgttgttca aactgctgat cagaacgctg cttggatttt tctttgcgat
    57301 acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat cacttcattt
    57361 ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat tcttttactt
    57421 tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc gagcaaaagt
    57481 gattatcaaa tatgtaaaat cagctacttt tttcttaaac gtttctttat actaaatata
    57541 aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt ttcctgaaaa
    57601 cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt tgaactatac
    57661 aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag tgatcacttg
    57721 ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa aaaaatgcaa
    57781 acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat ccaactactc
    57841 actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac gggagctttt
    57901 aacagagatt cttatagaac atccgcactt tatcgaacgc ttcaaagtta agatgccatt
    57961 tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg atcatattat
    58021 caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa agttcatcca
    58081 agaagcagtt gaatcgctta ttcagcaaaa tgcctatctt cccgcattcg aattgatcaa
    58141 tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac gaacccttct
    58201 tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac ctcatgcaga
    58261 aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg cctcttattc
    58321 aaaacgctac tctataaaaa tcctgaaaga agactttcgg gaaaaagaat tttctaacca
    58381 aaagaaaaaa atagataaaa aactaaagaa acggtaaaga aagacgattt caatgaaaaa
    58441 tagcaagtaa acgataacaa ccatcctaaa tccacaagaa atacagcaga ccttgcttta
    58501 aaaacacgaa tcatgcaaag gatgaagtaa agaagactta acgcgtaccc aatattagtc
    58561 atttgactat taggtacgcg ttttgtttta taagtcatga caaatttcct tcgttgctgg
    58621 atagattttc cggcattgtt gatagatttt atgatacttt tctacatttt gtaagagagg
    58681 ttccgctgca tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg tgtcgaacca
    58741 ccctaaccct agtgcagcaa tcattgttgc gcctaatgca ggtccttcct ccatacttaa
    58801 acaatagacc gttgcatcga aaatatcagc ttggatttgt agccatgcaa gatttttcgc
    58861 gcctcctccc accgaaacaa tacgtgtaaa tctgcgaccc gctagttctt tacgtttcaa
    58921 tcccaccatt gacaaatgct cattaaaaat ttagaatatt cacaagttta acgacaatta
    58981 tgaaaattta tgtcgtgcta aaggagtttt gttattggat gaaaagttag atataaaaac
    59041 tgcgatcaaa gacacgttac ctaccgtttt cggttatatc ggtattggac ttgcatttgg
    59101 tatcgttggg aaagctgccg gatttcatcc actagtcgtc acgttgatgt ccctgctggt
    59161 ctatgctggt tctgcccaat ttatcacagt cagcatgctt gctagtcaca gcccattgct
    59221 ttccatcgtt ttctcgacct ttctagtcaa ttcccgaatg attctgatga gtatgacgat
    59281 tgctccttat ttcaagaaaa atcggctgct tcaaaatctg ctgattggca cattgctgac
    59341 agatgaaagt ttcgcactgg gaatgaataa attgaactat actggacaaa agttaaactt
    59401 tcgttggatg aatacagcta attggatttc ttatttgacg tgggtgggtt cttctcttgt
    59461 tggcgcactt ttagggaatt ttattactga tccgaaaaag tttggtttgg atttcgccat
    59521 cgtcgctatg tttatcgggt tactttatct tcaagtcatt tctgatagaa acacctctaa
    59581 acgattacag ttgatcctga ttggtctcac tttgattctg gtatatgtcg gactgatttt
    59641 tatcccaagc aacttagtga ttgtagttgt aacactgatt gggtgcggat tgggggtgtg
    59701 gatcaaacat gccttctttt gagtttacat tgctgactat tttaggttgt actttagcaa
    59761 cttggctttc tagggtccta ccatttgtct tactgaaaaa attcgattta ccgcaaccgt
    59821 tgcttgagta tttaagtttt gtcccgatcg tcattatgtc tgctttatgg ttcagcagtc
    59881 tatttaccca aaatatcgga catctgccgc agatcaatct cgaaaatgct ttggcttcag
    59941 ttcctacact tttagctgct attctttcaa aaagcttatt ggtgatcgtc ttggcaggaa
    60001 ttctttccct ttcgttgatt cgcttattat aaataaaaaa acaagagctt atggcaaatt
    60061 actgtcatgc gctcttgttt ttatcaaagt caaataagaa aaaaatcggc gtattcttgc
    60121 ttatccgttg aacggaccac taacaacgac ttttcctaac atatgtcctg tttctacgtc
    60181 tttggttgct tgtttcaagt tcttcgcatt catcccatct gaatagacct tgctcaatgt
    60241 actgcggata atcccttcat ttgctaaagc agcaatgtgc gctaaagctt ctccttgcgt
    60301 ttcgatttca tagttatagt ctgttttagc gaacatatac tcccagtcga agctgataga
    60361 ttggtttttc caaacaccta tatctaacgg ctctttgatc cctacgatcg ttcccacatg
    60421 tccaaatggt cggacaaggt gcttgatttg atcaaagtag cgggtaatat cgaataatac
    60481 agcgacatac tctacttgat cgattcctaa ttcacgaaaa cttttactta agtcgtgatg
    60541 ataatcgatt ggatagtcta cacctgtttt tttcagccat tcaaaattct tcggacttgc
    60601 agtcgcgtag acttctaggc cagcccaatg cgctagttga ttcaaaatcg aaccgacgcc
    60661 cccggatccg ttgatcacta agattttttt cccgcgattg gcattttctt ctggagttag
    60721 accaaatttt tcaaataaca attcataagc ggtcaatgag gtcaacggca aggctgcagc
    60781 ttcttcatct gaaagatttt ttggtgcaag agcgacaata cgttcgtcaa ctagttggta
    60841 ttcttgattg cttcctgctc ttgttgttgt acctgcgtaa aaaacgcgat cgccgacaga
    60901 aaatttttgc acttcgtcac ctacagcaac aactttcccg actccatcaa aacctaagat
    60961 acgtaaagca tttcttatcc cgttatcttg gcgaagtttc gtatcgacag gattaacaga
    61021 tactgcgttg acttttacca gaagatcccg tgaactgggt acaggtatct gttctttttc
    61081 atcaataaag ctttttggat catcgatcgg caacccttca taaaaaccga ctaccttcat
    61141 taattccttt tctgacatac gaattcctcc ttagcttcat caagttggag catccataca
    61201 gtgttcattt caatatatat agtatgctat ttgttccacc ttttttattc atcataatta
    61261 ttctcttact taaagtaaac tatttgcact tttttggtta aaaaagaggt tgcgacaaga
    61321 cttttgtcac aacctcttat aaacggtgtt ctcctaccaa ctcttcggtc acaagtcaaa
    61381 atattcatca aacatgagaa gctgtttttt gaaattgctc cttgtgactc agagttaaac
    61441 ggcaggctca caacctctga tataaacggt gttcaatcaa ctgaccctcg gtattagctc
    61501 aaaaaacgac aaaatatgaa gagctatttt tgtttggctg ttcttattac ttgatacagg
    61561 acagcttttt cacgacctct aattcacggt gttcaagcaa gaaatcattg ttcactgaaa
    61621 agcgttggat gttctttttc aaaggtctct aagatctctc gtacttcatc agtagatttc
    61681 gtattcatca actgaactcg caagtcattt gctcctggaa atcctttgat atagatttta
    61741 aagaaacgat gtagtcctgt gatggaacgc gggatgattt ctgaataatg atcttgcaga
    61801 tctagttgca gacgaagtag tccgatcagt tctttttctg tatgttccct cgggtctttt
    61861 tcaaatgcat aaggattctt gaaaatccct cggccaatca tgatgccatc aacgccatat
    61921 ttctcggcca attcttctcc tgtctggcga tcggggatat ctccattgat cgtgattagt
    61981 gtttgtggag cgatttggtc acgtaaagca atgattttag gaatgacttc ccaatgtgca
    62041 tctactttac tcatctcttt acgcgtacgc aaatggacag aaagattggc tatatcttga
    62101 tgaagtaggt gactgatcca ttcttccatc tcagacattt ccgtatagcc gatacgcgtc
    62161 ttgacgctga caggcaaacc gccagcttta gctgcttcaa tcaattgtgc cgctacttct
    62221 ggacgaagga tcaagccact gccttttcca cgttctgcta cattagggac tgggcagccc
    62281 atgttgatat cgattccttg gaagcccatt tctgccatag caatgctcat ttctctaaaa
    62341 aattctggct tgtctcccca aatatgggca accatcggct gttcatcttc tgtaaatgtt
    62401 aatcttcctc gtacactgtc ttttccatct ggatgacaga aactgtctga gtttgtaaac
    62461 tcagtaaaga agacatccgg tgctgctgca tgctttacga catggcgaaa tacaacatct
    62521 gttacatctt ccattggtgc taaaacaaaa aaaggctttg gcagctcttt ccaaaaatta
    62581 gtagtcattt atttgttact ctccattcta tcaagcagtg aagtcgcaat ctttctcaaa
    62641 aacattgtca ttatactagg aaacaaaaaa agaagcaaag tgaacagctt aaaagatgtt
    62701 tctgattgag caaaaaaaag actgtgacaa aaatcttatc acagtccatt ttccggaata
    62761 aatggtgttc aaaagcttgc atttgcggta ataagtccaa ccaaacgaaa aataggagga
    62821 gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca caacctctcc
    62881 actaaacggt gttcaatcag ctgaccctcg gtattcgctc aaaaaacaac aaaatatgag
    62941 gaactatttt cccgtttgtt tctctaatac tcaggtcaaa acgctgattt cacaacctct
    63001 tttctaactt ctcaatcctc ttcctttatt gatcaaatac caagtaacgg cgtacaaaac
    63061 aacgatgaat aacacaagta cgatcatcga tgttgctact ggcacatcga tcgttccaag
    63121 gaatccgtaa cggaaaccgg agatcatata aacgatcgga ttgacttttg aaacagcttg
    63181 ccaaaagggc ggtaacatag agatggcata gaaaacgcca cctagataag ttaacggctg
    63241 caagacaaat gtaggcacga tcgatacatc atcataagac tgagcaaaaa tcccgttgag
    63301 cagtcctgct aatgaaaaca agattgccgt catcaataat gtaatgatga ccatgaacca
    63361 tgaatacaca tgaagtggta caaagaacaa ggaaatgatc gttacgagag agccgacgag
    63421 aatactgcga cccacaccac caatcacaaa gccccaaata atcacatgcg taggaacagg
    63481 tgctaccaag atttcttcga tatttttctg aaatttttga gagaagaagg acgaagaaac
    63541 attggcatac gaactagtga tagcagacat cataatcaaa ccaggaacga tgaattccat
    63601 atatgaaaaa ccacccatgt caccgatccg cccaccgatc atttttccga aaataacaaa
    63661 atacaaggat gtcgtgatca ctggcggaac cagtgtttgg acccatatac gcaaatagcg
    63721 gttcgtttcc ttgatagcta aactttttaa tgcagtaaaa taaagattaa acatttttct
    63781 cctccgtatg attattttct tctgtgattt tcaagaacag ttcttctaaa cgattcgact
    63841 tattcctcat agaaagaact ttgattcctt gtcttgtaag ctgatcgaag attccgttca
    63901 ccccttgatt tcgttcaact tcgacagcga ttgtctgctc atcttcaaat gtacaagcat
    63961 atccttcaat cacaggtttg gtatcatatg gcgctaaatc aaagataaat gtttcaaatt
    64021 gcagttttga cagaagctct ttcatacttg tattctcgat cagttcaccc gattggatga
    64081 ttccgatgtt gcgacaaagc atttcagctt cttctagata atgcgtcgtc aaaatgatcg
    64141 ttgtaccatt ttcgttcaat tctcgtagaa actcccacat ctcgcgtctc aactcgatgt
    64201 caactcctgc tgttggttca tccaagatca gcaaacgtgg ttcatgcatc aatgccctag
    64261 caatcatcag tcttcgcttc attcccccgg aaagcatacg tgcacggaca tttctctttt
    64321 cccaaagatt ggactgcttc aaatattttt cgctgcgttt catcgcttct ttgcgagaga
    64381 caccgtagta gcctgcttga ttcacgacga tttgctggac cgtttcaaaa gggttaaaat
    64441 tgaactcttg tggaaccaat ccaatctgtt gctttgctcg aactagatcc ttgtccagat
    64501 cataaccgaa gacattcact tttccagatg ttttattgac taaagaagta ataatcccga
    64561 tcgttgtaga cttcccagct ccatttggcc ctaatagcgc atagaaatct ccttctttca
    64621 ccgaaagatc gattccccgc aatgcttcga ccccacttcc atagatcttt ttcaaattat
    64681 ttatttcaag cgcatttgcc atttatttcc tatctcctta tagacatgat tcttaattgt
    64741 atcatggaat acagcagatg aaaaaacaac ttggcttcca cacaaaaaca cacctgctaa
    64801 caaagaggag atgtgttttc tagttcatga tcatcttcga tagaataact atctaaacaa
    64861 ctctggaact tttaaaatca taaaagtacc gacagcaact actacgatga catatagaag
    64921 atccttataa ctgaggttct tgtctttttt attcatgtta agctttcctc cgtcctttta
    64981 tcgaaagctt ttttctttta ttttaaccga aataaataaa atggaaatag ttattttcaa
    65041 tttctgtttt cgctgtttgt tttacggaga actttgccat ggaacgtgcg tctcgtcgct
    65101 gatgctaagt tttttcgata aaagctgcta gaaggaagac agcgtggttt attttgtatc
    65161 gtcttttgct aaatcttcca agatcatctg gacagcagac tcgttcccat tgaattctgc
    65221 cacttttttg gcatcaatgt acttcttttg ataatcgtct ttttggaccc acgcatcatg
    65281 cttcgtttga taaagttaat caaacggata ccactgacgc tgttcatcga acaacaaact
    65341 ttctttttgg gcctgttcaa ctatggattt aggataattc aaaactttca gcaaggcaat
    65401 cgcatttcgg gtccttgaag gtccttcttt taatttgaaa tcaaaactga ttccttttcc
    65461 ttctgttact tgttcttcaa agtggacatt ctcacaataa ttctttaaaa tctctgtcaa
    65521 ttcgatatca tgtgtggcga caaatgctaa agatggatac tccgcaagcc accgaacgac
    65581 tgaagcggaa gaagcaatcc gttcgatcgt atttgttcct tttaaaatct catctacgaa
    65641 gcagtagcag cgttctttgg aagccacttg gtccagcaaa cgtttgatcg atttgatttc
    65701 tgaaacaaaa taactgtcgc cttcaaataa atcatcttcg attgccatgg aagtcaacac
    65761 atgtccaggt tgcagggtaa actgttctgc aatcgctgtt tggatcgtct gtgctagaat
    65821 acagctgatg gctatacttt tgacatacgt agattttcct gatgcattgg aacccgtgac
    65881 taatgtattc ttctgccagt tgactggatt aactaccgct tcttttaaca atggatgata
    65941 gatatctttc gctgtcacac cgccctcagt aaactctggt cggcaagtga tcggcatata
    66001 ggtgcgataa ttcaaaacgg ctgctgcaac ttccaattct cccagcaatt cccacagctt
    66061 gatggcttca gttgaatgct tttctaattt agtgagaacg aaatgatagg agataaatgg
    66121 cagcatgaac atgatgttga catattcaaa aatcaattct gcttcactcc cgctcttcat
    66181 tcgaaatgaa aaacctaatt tagggatgtc tcttaatggt ttagtttgct gtttcagctc
    66241 tttttgaagt ggtgtcgtca tttttgctaa ctgattggcg gctgaaatcg ttgaaaccaa
    66301 ataactcatg ctattcagct ctgtttctag tgtttgtttc ttcactagat aatagaccgt
    66361 attgaatact aagccaccga ttgctagata gattcctagt acttgcccta aaagaagcaa
    66421 acctacaccc accagcggaa gcaagccaag aaaaataaat aaacctacgc gtccaatctt
    66481 tttacttttt ccatccgcta gatattgttt tgcaaaatta tgatcttttt ttcctaaacg
    66541 agcgaattga tattggattc tttctctcag ttgaggattt tcctgataaa aagcaattag
    66601 tttttctaac tgataatctt ctccaaaatc aaagctacgt aaacgctgat acaacgcttc
    66661 tgaacctaca ctagaatagg tactgttgat cccttcaaat acttcgaaca tatccaagtc
    66721 ataccaagta agatcgtcga tttcactatc ccatgaacgg aattttttct ccgtgagcca
    66781 cgcatccttc aaactttctt ctttatcaaa tctcggttga taaggaattt ttccccaatt
    66841 actacgaact gtttccttta ctttcaaacg tgaaaaaatg tctaaaacaa ctaataaaat
    66901 aacaactgca ataataatta aaacgataaa ttctctttgg cccatatccc tctccgttcc
    66961 ttgatttgtt agttttagta tagcactgtt gcgctatttg aaaagggggt acaaaaataa
    67021 ctgtcttcgt tacctaattc gtatcaatca caccaaaata aaaacacctt ccaaaaaaga
    67081 agatgtcttt aaaacgagat acaatttttt gtcattcact tcaggtaaat tagagccaat
    67141 taaaccctcc gcaacttgac ggagatggag aagatgcccc cgtctaatct agcggtcatc
    67201 tctcctccca ttccttccac caattttttt gacaggtaaa gcccgattcc gctagattcc
    67261 gtatttgtgc ggctggtatt ttcggtataa aaacgctgga agactttttc aacagaggtt
    67321 tgcgctcctg gtttgatagg attggccact gttaatcgaa tgaatgaatc ctcttttgaa
    67381 aatgtcacct ttgcttgtcc atctgcataa cgcaataaat tctgtatgat attttgcagc
    67441 actcgcagca acatgagcgg atctgctaat acagttgtat ttatcgagtg ttcagcgaac
    67501 gctacctcga tatttttctc agaaaattgt tcataaaaag agaaaaatac ttcttccacc
    67561 tctttagaaa aagaaagcgt atggagatcc atttcttttt gcttcgtctc tattcgagca
    67621 agatcataaa actgatccgt catactgagt aatcttgcaa cagattgttt gatgatcgtt
    67681 aaatacttct cccgtttctc cgtatcctct acctgttcca gtaattgtac ataaccgtta
    67741 atagcagtca aaggagttct gagatcatga gaaaggccga cgatcgatag tctgatgttt
    67801 tcttccattt cttgaaatgc ttgtcctttt tgttcatttt catccaccca tgtattcagt
    67861 gcatctacta ggtccattag attcttttct cgaaattcga ctgaaagacg accaccatat
    67921 tcttgtcgtt cagaaagagt ggcgattttc ttagttaatc tcttgatttc cctttgcagg
    67981 aagaaaataa aacttcccat aaagataaca acgagaagca acagccactt aatcaaatct
    68041 aaaccccact ccccacaccg tatgaatata cacagcatgt gcctttgcta gtttccctcg
    68101 aagattggaa atatgcatat tcactgtttt ctcactatca aaatatggtt cttgccaaac
    68161 tgtttcataa agatttgctc gcgaaaatac ttttttcgga tgttctaaaa aaagcttcag
    68221 cagatcgaat tctcttcctg tcaaatggac agccacacca ttcacattta catccctcga
    68281 ctctttgtcc agtaagattt ccttgtaata gatgcgttgc gacagatctt ttacttggac
    68341 agaagtctga tgacgaagtt ggatgccgat tcgtaacaac agttcttcga tatcaaatgg
    68401 tttcgtcaca tagtcatccg ctcctgctgc caacaaggaa actttatctc tttgatcgct
    68461 ttttgctgaa agaacgatga tcggaacatt cgatgtctgt cggatttctg ctaacaatgc
    68521 ttcacctgaa agccctggaa gcatgagatc tagaaggatc aaatcgacag gatatgtgct
    68581 taacaataat tttccttccg tacctgaata agcatcaaga agtttgtatc tctgttcaag
    68641 aacctcctcc agtaaagaat gaacagcttc atcgtcttcg ataatcaaaa tagtttccag
    68701 caggaacacc tacttaatgt cagatttttg gaaaataaac attcctagag ctgatgatac
    68761 cacgattgtt actagactga ccagaatcat tttcggtgct tgcgaataag ttgcttgttg
    68821 cgcaaagtcc gtatacatga gccacgtttc cgtaaaccac tccgttagaa attccaagcc
    68881 tttgattttt gcgaaaacac cgggaacgaa ggccgttccc atgatataaa gaaaagaaag
    68941 aagcaaactg acactggtac ttctagtgat gaatgtcaaa gccactggaa cagataatgt
    69001 cgctaatatc agcagaagca atacaggaaa tacttttaga acataatttc catagttttt
    69061 gattccctca acttcaccaa atccgaaagc aagtgtgtaa gcaatcatgg ctagccccgt
    69121 aatcaaaacc acgccaagtg ttgtgatcaa aagcgtaacg agaagtttcg acacataata
    69181 agtcattcga ttccgtccta aagataacgt attgcgaatc gtaccgtttt gaaattcttc
    69241 cccaatataa aagcacgcaa atgctgcgaa agccagaaga atccatgcag ccattttttc
    69301 caccattaaa atccctgttg caccgttgat gactgtatcc gttgcttggt ttaattcatt
    69361 gccgtatttt gtatgcatat accattcgtt ccaagaataa aaaagcggaa gtacgaccat
    69421 cagtcctagt gagacccaca ttttacggct cttccatact tttatttttt cagcagttaa
    69481 tagattaaac atgtggattg cctccagtta attgtaagaa ataatcttcc agtttttgcc
    69541 caactaggtg gataccatcc acaggaactt ttgcctctac caatgcttga ttgatggctg
    69601 ctacttggtc aattccttca aaaagctgga taacacggct agattggaca aaataatccc
    69661 tataaccaag agagtcgaga accgttactg cttgttccgt cgccgaagtg tcaattttta
    69721 taaattgacg agattcttgt gccaattctt ctttcgataa ttctttgatc aagtgtcctt
    69781 catgcaaaat accgtagtga gtggcgatct gtgacaattc atctagcaag tggctagaaa
    69841 gcaagacggt gatgccccgt tcttttacca aacgttggat gatttctcgc atttctgcca
    69901 tccctgctgg atccatccca ttcgtcggtt catccaaaat caaaaattct ggattcgtga
    69961 tcagtgcatt tgcaatagct aaacgctggc gcatacctaa agagaaattc tttgctttct
    70021 ttttccctgt attttccaat cgcatcattt tcagcaggtc ttcgatttct ctatccgaca
    70081 caccgccgtt cgctgcttgg atacgtaggt tatctcttgc agttaattct ggataaagag
    70141 caggggtttc aatcgattga cccatacgtc gtcttgctgc ctgcaaatcc gtcgttccaa
    70201 ataattcgat cgaaccttca tcaatcgaga tcaaacccat aatagttctc ataaaggtag
    70261 acttacccgc tccattctcc ccaatcaaac catagatcat tccacgtttg atttcgatcg
    70321 atactttatc taatgcttta gcagcaccgt attttttggt tataccagtt gctttcaaga
    70381 ccgtttcatt tccaaaatcc atacttatcc ttctttctta ttgataagtg aagtatagtt
    70441 gacgggtata aagaaagcag ccagaaatgt ataaagaaag tgtaaatttt ccaattgaat
    70501 ttcaagaaaa atcagactgt ctcgcagacg tggttgagtt gtctgccaat caaagagcgc
    70561 accaaacagt gctaatccaa gtggactggc caccatggta atcgttgtta tcgttgacat
    70621 cagacgtcct tgtatatgcg ttggaacttc tcgctgaagc cagaccatat aaaaagcaaa
    70681 agaaaacatt aatccttaaa aacggactta tgaaaaataa tacatgccgt ttgggattta
    70741 caattagcta ccaaataaga ggttatgaca aaagactttt cacaatccct tcttccgaat
    70801 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatttatca aacatgagaa
    70861 gcaatttttg taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaga
    70921 agcggataaa taatattgtt tgatgatact ttatcttttt cccgtttgtt tatagatcga
    70981 atgatattat agaccaagaa tcctacctat taacatagct aaaaacacaa aaaaggcact
    71041 ttccaaattg tggaaagtgc cagaaaagtt aggattaagg taactgcgct cagcattgct
    71101 tcgcccagta cgattctcgt aactcgtgaa ctcgaacgat aatcgcaatt aacgttttga
    71161 gaactgtgaa gctttacggg ctttcttaag acctggttaa acaaaactct attttattgc
    71221 attttacagg aatgtatttc atgcgaaatt aataagtctt tgtttataga gttttactag
    71281 ggtataaaaa gttgtatgtt atcattacct caaaacatta cctcagcttg gcgagttggt
    71341 tgattgaaga ataaatcatt tatctagata tctcaataaa aaatgatttc taagaaactt
    71401 gtattttcgt gttattattt ttttgcccta tcaaaatttc taattcttct agcgtaatat
    71461 gattatgaca cataatcgat tcaattactt caatacctat ttttttcgag aaagatccct
    71521 tttgttcact cacaaaaata ctttcagaag acatatataa ggaacgaagt tttggaatta
    71581 gtatatcgta caaatagacc accataaaat cgtccttgca accattctca aaaagaatta
    71641 aatttgctga ttgtgttaca tatatcactg aattacattc atggtcaatt ccaaaaacaa
    71701 tgtctacttc attttctttt ctaattcgcg cagttacatt tttcaaactt tcaccattac
    71761 ttataaatgc tttagttact gtaagctctg atgtttgttc agatattcct tttataatat
    71821 tttgttcatc agccacattc cccataaatc cgccgattcc ttttaagtaa taattctcac
    71881 ctaagagtcg cttgcattca ctgaattgat aaaaaaacca gttaaaaaaa tcttctggaa
    71941 aaataaattc tgatcgaact ttatttatat ttttagctcc tattaatttt ataactcgat
    72001 taatgttcac ttgctgcgat gaacatataa ctgaataaat tgagttgttt aattcaaaaa
    72061 aacaacttta acatatgcat cattaattcg ttatttttta ggtagatatt gatcattgtt
    72121 atctctcttt ttttgcttcc catactccaa cttagaaatt gccgttataa aatttatttt
    72181 aaaggtgact ttttcccctg aagtatcggt agtaggaata cttaatacct cagcttctga
    72241 ggaggtatcc caattatagt tatactttgc atcatcacca taaagaacaa ttccattttt
    72301 tttatcttgt gccgttagct ttactggttc gcttactttt cttgttaata tcttggactt
    72361 tacatcatcg atattgctta ttttatcaag cttaaataat ttacaaatta atttcgtact
    72421 agtttttata tttgacgaga gtgtaaaata ttttgtgtaa atagaaaaaa ggaagtccct
    72481 tctgtagaat agagttacca caacacattc acagaaaaga ggacttccat atgaacgatt
    72541 ttactacaga aattctaaag actctagcga acaaaggcga tttgaatgaa ttattccgtg
    72601 tccatttgga aaaagctgtc aatacgcttc tcaaaacgga gttaacggct ttcctcgatt
    72661 acgaaaagta cgatcgcatt ggttttaaca cggggaattc tcgtaacggc tcctatgacc
    72721 gtacggtcaa gaccgagtac ggggaacttc atctccagat tccgcgcgac cgcaacggcg
    72781 agttcaagca acagactgtt cctgcttata gacggacgaa tgatacctta gaggagaccg
    72841 tcattcacct cttccgaaaa ggtattacca tgtcggaaat cgcagacttg attgagaaaa
    72901 tgtatgggca tcactacacg ccccaaacca tgtccaacat gactaaagtg ctgactgaag
    72961 aagtaaatgc atttaaagtt agaactctaa atgataagta tgtcgctatt ttcatggatg
    73021 ctacttatat tcctttaaaa cggcaaaccg tctccaaaga agcaatctat attgccattg
    73081 gtatacgaga agacggcact aaagaagtac taagttatgc gattgctccg actgaatcga
    73141 cctacgtttg gaatgagttg ttacaggaca tttactccag aggggttcat gatgtcttac
    73201 tgtttattac cgatggctta aaaggcatga aagatacgat tcaccagatt tatcctaaag
    73261 ctaaatacca acattgctgt gttcacgttt cccgtaatat tgctcataaa gtacgtgtca
    73321 aagatcgaaa agaaatctgt gatgatttta aggctgttta tcaagctagc tcaaaggaag
    73381 aggcaaatac ctttttaggg agtatgattg agaagtagca aaaaacttat cctaaagtga
    73441 cgcagtcact gataaaaaat caagatttat tgacttttta tgagtttccg cctggtatcc
    73501 gccgaagcat ttactcaact aatttaatcg aatctttcaa gaaacaaatc aagaaataca
    73561 gccgcagaaa agagcagttt caaaatgaag aatcactaga gcgtttccta gtatccatct
    73621 ttgatacata caatcaaaaa ttcttaaata gaagccataa aggcttccaa caagtgacgg
    73681 atacattagc ttcaatgttt actgagtaac ccattatttt gcagaaggac gagttattta
    73741 cacaaaatta ttgacgctcc ctccaaatta cttcatcaaa acattgatat aatttttatt
    73801 atatcagtat ttattcttga tacataaatg agaaaataaa tactttaaat ctattgacta
    73861 caagtagtca ttaagtcttc ataagatgta caatatgaca ttaaaaaaat aaaagcttac
    73921 gaccatccgt taaatctgac actaaataat ggactgcttt cttttgtatt agcaggttac
    73981 gttgactatg aatattcacc agattatttg gagaaacctc ttcaacacga gaacaatgat
    74041 attaatttta gatttgtcta cgagtcaaaa agtaaaacat ggttagttga tcaattaagc
    74101 acgataaaca caagcttcca tgaattacct aaacctgaaa atgaagttga gatggtcatt
    74161 aaaatcttct aaaaaagaag cgttgaaggg gaaatattcc tttcaacgct cttttttata
    74221 tgcttagaaa cataaataaa ttgtatactt tctttttagc ccctattact tttcacgaaa
    74281 aatatctttt tttcgacgct agcgtttctc tacttctaat actgtacaca gtttttgtat
    74341 tattgaaaaa ttactcatta tttagcatta atccacatcg ttttatcaat cgaccttcat
    74401 actaaactac tttaaagtca tcttccttct cgtttttcat t
//
LOCUS       DAPBBR010000007        69297 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPBBR010000007 DAPBBR010000000
VERSION     DAPBBR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 69297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.007"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            169..1227
                     /locus_tag="RD488_000469"
     CDS             169..1227
                     /locus_tag="RD488_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDT7656569.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1231..2265
                     /locus_tag="RD488_000470"
     CDS             1231..2265
                     /locus_tag="RD488_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDT7656570.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2367..3083)
                     /locus_tag="RD488_000471"
     CDS             complement(2367..3083)
                     /locus_tag="RD488_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7656571.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3052..3837)
                     /locus_tag="RD488_000472"
     CDS             complement(3052..3837)
                     /locus_tag="RD488_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HDT7656572.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3828..4577)
                     /locus_tag="RD488_000473"
     CDS             complement(3828..4577)
                     /locus_tag="RD488_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7656573.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4875..5399
                     /locus_tag="RD488_000474"
     CDS             4875..5399
                     /locus_tag="RD488_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDT7656574.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5415..6914
                     /locus_tag="RD488_000475"
     CDS             5415..6914
                     /locus_tag="RD488_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDT7656575.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7002..7604)
                     /locus_tag="RD488_000476"
     CDS             complement(7002..7604)
                     /locus_tag="RD488_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7656576.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7708..8664
                     /locus_tag="RD488_000477"
     CDS             7708..8664
                     /locus_tag="RD488_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDT7656577.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8969..9925)
                     /locus_tag="RD488_000478"
     CDS             complement(8969..9925)
                     /locus_tag="RD488_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7656578.1"
                     /translation="MKKYQWGIVGLGTIAHGFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10099..10659
                     /locus_tag="RD488_000479"
     CDS             10099..10659
                     /locus_tag="RD488_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656579.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10652..11476
                     /locus_tag="RD488_000480"
     CDS             10652..11476
                     /locus_tag="RD488_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDT7656580.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11486..12103
                     /locus_tag="RD488_000481"
     CDS             11486..12103
                     /locus_tag="RD488_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7656581.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12121..12804
                     /locus_tag="RD488_000482"
     CDS             12121..12804
                     /locus_tag="RD488_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDT7656582.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13487..14770
                     /locus_tag="RD488_000483"
     CDS             13487..14770
                     /locus_tag="RD488_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7656583.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14786..15673
                     /locus_tag="RD488_000484"
     CDS             14786..15673
                     /locus_tag="RD488_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7656584.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15690..16526
                     /locus_tag="RD488_000485"
     CDS             15690..16526
                     /locus_tag="RD488_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7656585.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16529..17152
                     /locus_tag="RD488_000486"
     CDS             16529..17152
                     /locus_tag="RD488_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656586.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17149..18441
                     /locus_tag="RD488_000487"
     CDS             17149..18441
                     /locus_tag="RD488_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7656587.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18800..18897
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19013..19594
                     /locus_tag="RD488_000488"
     CDS             19013..19594
                     /locus_tag="RD488_000488"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDT7656588.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19597..20904
                     /locus_tag="RD488_000489"
     CDS             19597..20904
                     /locus_tag="RD488_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDT7656589.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21320..21808
                     /gene="purE"
                     /locus_tag="RD488_000490"
     CDS             21320..21808
                     /gene="purE"
                     /locus_tag="RD488_000490"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDT7656590.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21801..22925
                     /gene="purK"
                     /locus_tag="RD488_000491"
     CDS             21801..22925
                     /gene="purK"
                     /locus_tag="RD488_000491"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDT7656591.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22938..24233
                     /gene="purB"
                     /locus_tag="RD488_000492"
     CDS             22938..24233
                     /gene="purB"
                     /locus_tag="RD488_000492"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDT7656592.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24413..24790)
                     /locus_tag="RD488_000493"
     CDS             complement(24413..24790)
                     /locus_tag="RD488_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656593.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25046..25774
                     /locus_tag="RD488_000494"
     CDS             25046..25774
                     /locus_tag="RD488_000494"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDT7656594.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25774..26028
                     /gene="purS"
                     /locus_tag="RD488_000495"
     CDS             25774..26028
                     /gene="purS"
                     /locus_tag="RD488_000495"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDT7656595.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26030..26701
                     /gene="purQ"
                     /locus_tag="RD488_000496"
     CDS             26030..26701
                     /gene="purQ"
                     /locus_tag="RD488_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HDT7656596.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26702..28924
                     /gene="purL"
                     /locus_tag="RD488_000497"
     CDS             26702..28924
                     /gene="purL"
                     /locus_tag="RD488_000497"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDT7656597.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28909..30348
                     /locus_tag="RD488_000498"
     CDS             28909..30348
                     /locus_tag="RD488_000498"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDT7656598.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30371..31423
                     /locus_tag="RD488_000499"
     CDS             30371..31423
                     /locus_tag="RD488_000499"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDT7656599.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31420..31998
                     /gene="purN"
                     /locus_tag="RD488_000500"
     CDS             31420..31998
                     /gene="purN"
                     /locus_tag="RD488_000500"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDT7656600.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31995..33530
                     /gene="purH"
                     /locus_tag="RD488_000501"
     CDS             31995..33530
                     /gene="purH"
                     /locus_tag="RD488_000501"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDT7656601.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33546..34820
                     /gene="purD"
                     /locus_tag="RD488_000502"
     CDS             33546..34820
                     /gene="purD"
                     /locus_tag="RD488_000502"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDT7656602.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34942..35856
                     /locus_tag="RD488_000503"
     CDS             34942..35856
                     /locus_tag="RD488_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7656603.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35989..37554)
                     /locus_tag="RD488_000504"
     CDS             complement(35989..37554)
                     /locus_tag="RD488_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7656604.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37547..38998)
                     /locus_tag="RD488_000505"
     CDS             complement(37547..38998)
                     /locus_tag="RD488_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7656605.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39012..40028)
                     /locus_tag="RD488_000506"
     CDS             complement(39012..40028)
                     /locus_tag="RD488_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7656606.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40248..41336
                     /locus_tag="RD488_000507"
     CDS             40248..41336
                     /locus_tag="RD488_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HDT7656607.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41390..42916
                     /locus_tag="RD488_000508"
     CDS             41390..42916
                     /locus_tag="RD488_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDT7656608.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42918..44123
                     /locus_tag="RD488_000509"
     CDS             42918..44123
                     /locus_tag="RD488_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7656609.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44380..45357
                     /gene="guaC"
                     /locus_tag="RD488_000510"
     CDS             44380..45357
                     /gene="guaC"
                     /locus_tag="RD488_000510"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDT7656610.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45621..47045
                     /locus_tag="RD488_000511"
     CDS             45621..47045
                     /locus_tag="RD488_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7656611.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47506..48615
                     /gene="pdhA"
                     /locus_tag="RD488_000512"
     CDS             47506..48615
                     /gene="pdhA"
                     /locus_tag="RD488_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDT7656612.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48618..49595
                     /locus_tag="RD488_000513"
     CDS             48618..49595
                     /locus_tag="RD488_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDT7656613.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49620..51263
                     /locus_tag="RD488_000514"
     CDS             49620..51263
                     /locus_tag="RD488_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDT7656614.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTVTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51271..52677
                     /gene="lpdA"
                     /locus_tag="RD488_000515"
     CDS             51271..52677
                     /gene="lpdA"
                     /locus_tag="RD488_000515"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDT7656615.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52839..53114
                     /locus_tag="RD488_000516"
     CDS             52839..53114
                     /locus_tag="RD488_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDT7656616.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            53120..53887
                     /locus_tag="RD488_000517"
     CDS             53120..53887
                     /locus_tag="RD488_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HDT7656617.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            54055..55884
                     /gene="typA"
                     /locus_tag="RD488_000518"
     CDS             54055..55884
                     /gene="typA"
                     /locus_tag="RD488_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDT7656618.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            56145..57917
                     /gene="recQ"
                     /locus_tag="RD488_000519"
     CDS             56145..57917
                     /gene="recQ"
                     /locus_tag="RD488_000519"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDT7656619.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLRKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            58031..58333
                     /locus_tag="RD488_000520"
     CDS             58031..58333
                     /locus_tag="RD488_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDT7656620.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            58336..59499
                     /locus_tag="RD488_000521"
     CDS             58336..59499
                     /locus_tag="RD488_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7656621.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            59525..62953
                     /locus_tag="RD488_000522"
     CDS             59525..62953
                     /locus_tag="RD488_000522"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDT7656622.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            62974..64098
                     /locus_tag="RD488_000523"
     CDS             62974..64098
                     /locus_tag="RD488_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656623.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            64088..64525
                     /locus_tag="RD488_000524"
     CDS             64088..64525
                     /locus_tag="RD488_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7656624.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            64509..64847
                     /locus_tag="RD488_000525"
     CDS             64509..64847
                     /locus_tag="RD488_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDT7656625.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            64966..65526
                     /gene="rsmD"
                     /locus_tag="RD488_000526"
     CDS             64966..65526
                     /gene="rsmD"
                     /locus_tag="RD488_000526"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDT7656626.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            65523..66014
                     /gene="coaD"
                     /locus_tag="RD488_000527"
     CDS             65523..66014
                     /gene="coaD"
                     /locus_tag="RD488_000527"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDT7656627.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            66004..67047
                     /locus_tag="RD488_000528"
     CDS             66004..67047
                     /locus_tag="RD488_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDT7656628.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            67206..67934
                     /locus_tag="RD488_000529"
     CDS             67206..67934
                     /locus_tag="RD488_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDT7656629.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            68050..68295
                     /locus_tag="RD488_000530"
     CDS             68050..68295
                     /locus_tag="RD488_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7656630.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            68292..68510
                     /locus_tag="RD488_000531"
     CDS             68292..68510
                     /locus_tag="RD488_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDT7656631.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            68646..69185
                     /locus_tag="RD488_000532"
     CDS             68646..69185
                     /locus_tag="RD488_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDT7656632.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
BASE COUNT        22504 a        11941 c        15251 g        19601 t
ORIGIN      
        1 ttttttgtgt tctagtaaaa atcactttac ataagtttca aaagtttctt taatttccta
       61 ttgttcaata agtaacaatg taaagataaa attaaaaatg ttaatacgta ttagcaaaat
      121 aaaagctttt tttattgtga ataaatgaac ataattagga ggagaaagat gaacttattt
      181 gacatttttc gatcgacttt gacagatatg tcgattgtca gtgcaatcac ttcaacagtt
      241 tttattatat tattagggtt tgtttgtaga aaaaagggga ttttttctga atctgttgga
      301 aaaattctat cgaaagtcgt cttaacagtg gctttgccag cactggcatt tcgagctttc
      361 atgcaagata tcaatacaga attactgatg caaggaatca atgtcttgat ttggggatta
      421 gttatttata ttattcttat tctagtttca aaaccttttt tcttaagcta taaaggggat
      481 aagcaaacaa cgttgcgtgt cctgacgatc tttggttcta cgaccttttt cggaacgcct
      541 atcgtcagtg cgatttatgg tcctgtcggc gtgatgtatt cctcaatttt caatattggc
      601 taccgaatct ttttgtattc ttatggatac ataaaaatga gtggcttgaa gatggaagct
      661 aaaaatatca aagcgatgtt cgtcaatcca atcattatcg ctacttttgc cggccttttc
      721 atttggctgt tccaagggta tctgccacaa gtgtcagtta caggtgcaga aggagagata
      781 agccaagtag cgtttttgcg aattgaccag actgcaccgt ggctatttca gccgatggat
      841 tatttagctg gtttaagttc accattggcg tggctagcaa tcggcgcaac attaggtgaa
      901 gtaagcttca aaaaagctgc atctgaaaaa acttcatggt attacagtct agtcaaagtg
      961 gtatttgtac ctgcattgaa tatcgtgatt ctagcagttt tgacggcaac gaatattcta
     1021 ccagtcaatt ttgaagcact ggcaacaatc gttatcatga tggctacacc agctgcaaca
     1081 gtggcagcag cctatgctat cagttttgat agggaggcac ttttagcctc caatgcatcc
     1141 ttactgtcaa ctatttttgc tgtggtactg acacctgtat ggatcgttgt attacaaatg
     1201 attcatggca taggtttatt ttcataagaa atggaggaag aaagtatgag aatcgcatgt
     1261 tacggtgttc gtccgaacga gatagatttt tttgaaaaat tgaatattta ccattatgat
     1321 ctcagtcttt atgaagaact gttgacacat gacaatatcg tgtcagcaaa ggaccatgat
     1381 gctgtattgt tgaggggaaa ttgtatagca gatgagacca atcttgcaaa aatgcaggaa
     1441 tatgggattc gttatgtttt tacacggact gtgggagtca atcatatcga tctacaagcg
     1501 gcagctgatt ttggtatgac agtagcccgt gtaccatcgt attcgccaaa tgcgatagca
     1561 gagttatctt tgacttttgc catgatgctt ttgagaaata ctgcgtatac gacgatccga
     1621 acatctttca aagattttcg agtggatgag caaatgttta gtcgtgaaat cagaaattgc
     1681 acagtaggga tcataggaac aggcaggata gggttgacgg aagctgtttt gtttaaggga
     1741 ctaggagcca aagtgatcgg ctacgatatt catcagacag aagctgctaa aaaagtattg
     1801 acgttccact cgcttgaaga gttattagcc aaaagcgata ttgtcagtat tcatgtacct
     1861 catatcccag gtgaaaacga tcaaatgatc aatgaaggat ttttagctca aatgaaaaaa
     1921 ggtagcatct tgattaatac agcccgtgga gagcttcaag ataatgaagc tattttaaga
     1981 gctttgaaaa gcaatcattt agctggtttt gcaaccgatg tttttgcaaa tgaaacagag
     2041 gtttttttcc gatccttcaa gccatgggag acgattccag accctgctat ccagcaatta
     2101 gtagaaatgt accctagagt tcttgtaacc ccgcatgtag gttcaaatac agatgaggca
     2161 ttatcaaata tgatttcgac aagtttcgag aactttcgtg aaataataga aactggaaaa
     2221 acgaaaaatg aggtatctct tcctaaagcc cgtcaattaa gataagaaaa catggatatt
     2281 cgtcaataaa atgtttaaaa atagtccaag taaacagttg ttacttctgt atacttggac
     2341 tattttgtat gggataattc gatgactcaa cagtaatctg tgagcttttt ccgcccattc
     2401 tttgtcaatt cataacaggt tagcggccgg ccgatttcca aatatttgat tctttcgttc
     2461 aatatatctt gttctactaa aaaattcaaa tatttcttga cggatatacg tgacagtgag
     2521 cttttttgag ccagttcttt tgttgaaaaa atagtatctt cttttagaat aaatgcactt
     2581 atttttttta aagtcagttt tgacagacct ttaggcaaat cgatgaatga tggtatttcg
     2641 tgaatgggag tggtgtggtt gaatacttga tcgatcaatt tctgatcggc tttttcagtc
     2701 gtttggattg tctgagagaa agcaagatac ttttcgatcg ccagctgaaa acgttgcaaa
     2761 gtgaacggtt tgatcaaata atctaaggca ccgtagcgga tcacattctt tatggtttcg
     2821 atatcatctg cagcagtgat caaaatcact gggatatcat ttccttgctg tctaagccaa
     2881 gataaaaaat ggataccact ttcgccaggc atgtatacat caagcagcag cagatctgcg
     2941 tttttttgtc tgaaatattt ttttccttct tctacatttc tgaaactttc gattacgttc
     3001 atattaggga tgctttccac aaaagtacga ttcaattctg caaccattgg atcatcttcg
     3061 attatcagga catttgtcat cattttgatc ttcctttttt ggtaattcta gatagacgat
     3121 tgtaccgcca tttgtttgtt tggaaaattc taaaaatcca ccgtggcgtt tgacgattga
     3181 atggatgaga ttcaatccaa acccacgatt gattcccttc gtcgaaaaac ctagcgtaaa
     3241 tattttttct gagatttctt ctgatatccc gacaccgtca tcgcagacgg tcacgatgaa
     3301 tacttcagct tctgtgtcat agtttaaatg aatccggacc tgtccgtttc tttcatgttt
     3361 ttgtagcacg gcttcttttg cattatcaag taagttccct aacacttgca aaagtgaatg
     3421 gatggagtca tccatctcca ttttagggat aaaagaatcg ctttctaaca gcatttcaac
     3481 agattgttct ttggcttcgt ttattttgcc taataaaaaa ccggcaattg caggtacttt
     3541 gatcagactt gagacttggc caatctcttt tttataattt tgatttagct gctggataaa
     3601 atgggtgact tcttcatact tcttcaaatc aatcaaacca gaaatgacat gaagtttatt
     3661 catgaattca tgggtttgag ctctcatgga gtttatatat tgtttcgtcc ccccaagctc
     3721 ctccattaat ttcattactt ctgatcgatt tcgtaaagtt gcgactgctc ctaaaaaacg
     3781 gtcattgcta aaaagaggtg taacgctaga aatagtttct atcccattta aatacatgga
     3841 ttgagtccga acggtcgttt gatgctcaat cgtctcttta aacaaaacgt catatagatt
     3901 atcactgatt tttttcctac ttcgaaatcc aatagctgct ctgtttggta gaaaatgttt
     3961 tttgcaggtg tattgatcaa gaggatagtt ttatcagaag agatggctaa gattccttca
     4021 tctacttcat tttcgataat cgttttttca cttaactgtt ctgctatttc ttgtggttca
     4081 agtccaagca gtactttttt cattttttgg gcaagaaaaa cggcgcctat gatgcctacg
     4141 ctaagtccaa taatcaatga aaaaacaatc attttttgtc catctttgac ttgattgtca
     4201 atcgtgttgt ttgttaagcc aacacaaact gcaccaataa tctcttgatc ataataaata
     4261 gggacgaaat agcggaagcc gaaccctaac attccttctt tttcagagaa aaattcttgt
     4321 cctccaatca cttttttcac atcttcatga cttgagaaag gaagaccgat gtaacttggg
     4381 tctgcgtgag aatatcgaat gccttcaggg tccatgacaa cgataaaatc taaattcgat
     4441 gcaatcatga tttcatttgt tattccttga atcgcatgtg tcgggtcacc agtctgcagc
     4501 tttttttgga tgagtttatc attggcaacg attttagcaa tgctagagat tttatctgac
     4561 acactagatc ggttcatcga aagaataaaa ttcctgatca atatggcaga aacaatcaaa
     4621 gaaacgaatg tggagaaaca aacgacaagg atgatcgtgt tctggagctt taatggtttt
     4681 ttcttaaaaa aaggaaacat aggctacctc gaaagaattt attgtgaaaa ttttaacatg
     4741 aaaacaaaaa tttaacaaat tgtcaacgat aaacacaacc ttcctataaa aaacaccact
     4801 gagtcggtaa aagaagctat acagaatttt caaacattgg tatgatagac gtagaaatgg
     4861 aaggaggcgt gtatatgata gggggaatcg cacttgagac gatttattgg tatacattgc
     4921 tgatttgtgc aggattggca gtcctattga ttatttttgg agatgtattc gattttgatg
     4981 gcccgcttga tccgatgctt attatccctt ggttaacttt cacaagctta tttggttttc
     5041 taggtgagcg tttaacagat caatcatctt tatttttatt tattgctagt ggaggcatat
     5101 cgatagtgtt ggtatttttg cttaatttct atatattgat gccgatgaaa catgccgaat
     5161 caacgatgtc gtcttctgaa aaaactctgg aaggacaagt agctgttgtg atcacaccga
     5221 tccctgtacg aggtatggga gaaattcagt tgaaaagtgt taccggttcc attagtcgtc
     5281 cagcttgttt ttacagcccc caagaacaga cagctgagcg gggaacgaaa gtattgatca
     5341 ttgagatcaa ggaaagaatc tgttatgtca tgccttatga aagcatgata aaagcttaaa
     5401 ggagcgtgtg ttaaatggaa ataccagttg tttttatcgc gatcgcaatc gcagctttga
     5461 ttttactgat gttgctgatc gtctttgtag cgaagtacca gacagcaaaa ccggatgaag
     5521 cgttgatcat cagtggaagt tatttaggaa gcaaaaatgt gcacattgat gaaagcaata
     5581 acaaaatcaa aattgtgcgt ggaggtggcg cattcgtctt gccagttttt caacgttcga
     5641 atcggatcag tctattatcg agtaaattgg acgtctccac ccctgaagtg tatacggaac
     5701 aaggcgtacc ggtgatgtgt gatggtactt cgatcatcaa aatcggttca tctgtagaag
     5761 agattgctac agcagcagaa cagtttttag gcaagacaag agaagaactg gaaaatgaag
     5821 caagagaagt attagaagga cacttgcgct cgattcttgg ttctatgact gtagaagaaa
     5881 tctatcaaaa tcgcgataag ttcagtcaaa gcgtacaaga agtcgcttct gtagaccttg
     5941 caaaaatggg gttgatcatc gtttctttca ctatcaaaga ggtcagagac aaaaacggtt
     6001 atcttgactc tttagggaaa ccaagaatcg cccaagtcaa aagagatgca gatatagcag
     6061 aagcggaagc tctaaaagaa acgcgtatca aaaaagctca agcagaaaaa gaatcacaag
     6121 cagctgaatt acagcgacaa acagagatcg cagaatcatt aaaagaaaaa gaactgaaat
     6181 tagcaaccta caaacaagaa caagatgttg ctaaagcaaa agcagaccaa gcctacaatt
     6241 tagaaagtgc ccgagcacaa caacaagtaa tcgaacagga aatgcagatt aaaatcgtag
     6301 aacgtcaaaa acaaatcgaa ctggaagaaa aagaaatcac acgtcgtgaa aagcaatatg
     6361 attcggaagt gaagaaaaaa gcagatgccg atcggtacgc taaagaacaa gaagcacaag
     6421 ctcaaaaagt caaagaagtg actgaagccg aagcagaacg attccgtgtg gaagcactgg
     6481 cagaagcgga agccaataag acacgtttag ctggacaagc agaagccgaa gcagcactag
     6541 caaaaggaaa agcagaagcc gaagcaaaac aaaagatcgc caatgccttc aaggaatatg
     6601 gcgaagcagc tgtcttgagt atggttatcg atatgctacc gcaattgatg cgcgaagcag
     6661 cacagccgct aggaaatatc gaaaaaatct ctgttgtcga tacaggaagc agttcaggag
     6721 aaaccagtgg agcgaaccga gtgacaaatt atgccacaaa tttgctttct tctactcaag
     6781 aaacactaaa agcgacaaca ggacttgact tgaaggaaat cgtagagaat ttgtcgacac
     6841 gtgggactac tagccaagta aatatgtatg aagcgccaaa agaggcagaa caaaactcga
     6901 tgaaggaaga ataaagtagt acacttcacc gttcaatcaa aaatggagga agacttttta
     6961 aagttcttct ctccattttt ttattttatt gcaaaagaaa attagtcctc gctatttttc
     7021 ttttgttttt ggatcttagc ttctatctct tgtaaatttg ttcttagcaa tcgttctttc
     7081 ttttggagtt cgaccaaatc ttctgatagt tcttccttct tttctgtttc aggaggacga
     7141 agaaagaaat tgataccgat tgcaatgaat gtccctataa aagtatctag tacacgttgg
     7201 atagcataca aagcggattc gccttgaggg atgctcaacg caatcagcaa caacgtagct
     7261 attgcggaaa tgataccgga attattgtta ataccatctg acacgacgat cacaataata
     7321 actagaatag gaagcaagat caattctacc aaaaaatcat tgtgaaaata gcttttgaca
     7381 aaaaaataaa tgatagctaa tgtaccacct aatgtattgc cgatgatcct agactttcca
     7441 aaagaaacgg ttgtagtcaa gtcctgacgc aaagaaaaaa cagcagataa tgcagcaatc
     7501 atcgggattc ctcgttgagt caaatgaaaa aacaagatac ataaaaaaac agctaaggca
     7561 cttttgatcg tacgcatacc tagtcgaaaa cggccaaatt gcatagagat tctccttttt
     7621 ggtcttttta ctatcatacc taaacttttg tctgatagct agtttttcat tattcaagta
     7681 taattaaaat aaaaaagggg gaagtaaatg cgtataggaa tgcgaacagt caaaacagtg
     7741 atcagtgtct tcttttcgat ggtcacagcg ggtagcttat cgctgttgta ttggccagct
     7801 gcagggatca ttgcattatt aagtgtagga aataccaagc gctctacatt gcgtacgggc
     7861 atgaatcgaa tcgcagcctt tatattagct acggcaacag cactgttcag tttttttgct
     7921 gttgggtata ctatttttgg cttcagtctt tttttattcc tgttcatccc gcttgcctct
     7981 cgcttcaaat taaccgaagg gatagtagta aattcggttt tggtcactca ttatttagtg
     8041 gaggaaaaca tgtcttggca gctgatcggc aatgaagcgg gattaatggc gattggatta
     8101 gtatttgctt tgcttgcaaa tgtttacatg ccagatcgta cgaagcagct gaaggaaaac
     8161 caaatacaga tcgaaaaaga atttcgaaat attttgagac aaatggcaga atttctttta
     8221 tcagaaaata aagaagatgt gcagatcaaa tgcgaacatt tactgacatt cattcgcgaa
     8281 agccaagaag atgccagaga acatcaagaa aactactggc tcagacagcc gctatactac
     8341 gaaacttact tctctatgag aagagcacag gccaatgtga ttaaagacat gctggaaaat
     8401 ctagagagaa tccagcaacc agcttattat ggaaaacata tctatggttt attgatttat
     8461 actgcagaaa cattttcaga gtcaaatgat ggcagacaaa ttttaacacg tattgaagaa
     8521 gtttatgtat tgtatcggca aatgcctctg ccgactagtc gccctgaatt cgaggatcga
     8581 gcagaattgt tccagttttt gcagtctttt aaaagtttta ttgaaatcaa ggcagaattc
     8641 tcccaacaaa aaatccaaaa atagaggttg tgaattcagc taatattcag gtcaaaaagc
     8701 tgatttcaca acctcttctt taaacggtgt tctcctgtca actcctcggt cacaagtcac
     8761 aatattcaac aaacatgaga agctgttttt tgaaattgct ccttgtgact cggagctgaa
     8821 cggtaggctc acaacctctt tcttaaacgg tgttcaaaag ctttcctctg cggtaataag
     8881 tccagccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
     8941 agaacagctt tttcacaacc ttttaaaatt acatattttt ccatagaact tgcatttgat
     9001 ccaagatttc gatgacatct tttgtcaaga agagagagcg attgggcaag tcaccttcaa
     9061 tcatgtgtac catattcttt atttcgtaat tcattgcttc agatgtattc ccgctttcga
     9121 tgaattcctt tgtaccatct gtaaataaga tctccgcacg atcagcacgc gggtaatcag
     9181 caatcgtcac ataaccgttc tcaaaggcaa cgataccgac ttttggcatt tttgcctgaa
     9241 aagtcaagct gacagcagca agttcatttt ctttgttacg caagatagtg acggattgtt
     9301 cgtccacgcc tgtttcaaaa ggaaccattg tagaggcaac tacttcaggt tgagagctca
     9361 aaaagaaacg agcgaaagat acagcatacg taccgatatc caacagagct cctccagcta
     9421 attctggatt gaagaaccgg tttttagggt ctggttcttt gtaactgccg aaaggtgctt
     9481 ggatcatttt taaagccccc agttttcctg tatccattat tgagcgtaac tgctgataaa
     9541 gtggcatgtt gaagattgtc atcgcttctg ctaagatcaa attcttttct tctgctaagc
     9601 gcatagcgtc agccagttct tttttattca tcgtgatggc tttttcacat agaacgtgtt
     9661 tgcctgcttc caatgctgcc aagatatggt cgatatgctg tctatttggt acagcaatgt
     9721 acacgatgtc gatttcagca tcgtctaaca tttcttgata gcttccgtaa gcttttggaa
     9781 tattgtaacg gtgagcgaag ttttccgctt tttctgaagt tctggaagca actgctgtta
     9841 gttcgctcgt ctcttgattg aagctttcgg caaacccatg tgcgatggta ccaagaccaa
     9901 cgattcccca ttgatatttt ttcatctgaa aacgctcctt catagttgga ttgagtttct
     9961 tgtctgtcta ttattataac aaaaatcacg aagaataaag aggagaggac ttgaaacatt
    10021 aaaaaaaata aaagcagcga tttaagaggt gctttttgat caaaacttaa gtagaatagt
    10081 taaaaggagg ggataaacgt gcatcaagta tatattgatc ttattatgag tgtattatta
    10141 gaacagtttg aaactgaaaa aaatttttta gatgaatact tgctgatcag tccagaacaa
    10201 tggcaaaaat ggaaagatgg cgagaaaaat ctgccatctg aagcgatgca gaaagtaaaa
    10261 aatcttttca ctgattatga atggatgcta acgcaaaaga ttttgcgtca aacgattatt
    10321 tttcccgaaa aacgaaacgt tgccgttgca gagtacaagc aaatcaaaac acgcatcgcg
    10381 caaaaatggc ttagcagcaa agcagcaaaa gtcgagctga tccctttgaa aaataatcag
    10441 caggctggta gataccttga cttgaaagta agtattcaat atgatgaatg gggctatgat
    10501 gatattttga attttcgtct gccagcagat gttcaaaaac agatcgaagg agaaaaaatc
    10561 gaacttctcg attgggtgaa tgaaaatctg gaagaaactt acgttcatga ggcgaatggg
    10621 gaacgtgaag aacaacgaaa ggatttttca agtgaataaa tttttaggat ttggagcagt
    10681 tgtgattatg atcgcagcaa tgggctatgt tatttttagc gatgatgatt cgcatgttca
    10741 agccggcaat caagcagtcg aacgaacaag caccaaaaca actgctagta aagaaaagaa
    10801 cagtcaaaca accagcagca aggtaaagga caaagaaaca aaagatcgta cgtccaaaca
    10861 attgccagat gttaaaacag acgattggaa gctagttttg gttggtccag atcacaaatt
    10921 agaaaaagaa attgatgagt ctactcaatt ggcatcatta agtaacggat acttgatcga
    10981 caaacgcatt gctccagaat atgaagcatt tgccaaggct gctgaagcag ctggatttcc
    11041 attagtgatg gtctcagctt accggtctgt atcatcccaa caacaagttt tcgaacaaaa
    11101 tgtccaagat gtgatgagtc gtcaaggtgt atcagaagag gaggcgacaa agattactaa
    11161 agaaacgatt acggagccag gatacagcga acaccacaca ggtctggcag tcgatgtcgt
    11221 cgatcaaaac tggtacaaca gttatccttc tactgtattg gatgcaagtt acggagatca
    11281 gcctggagct aaatggatcg cagataatgc tgcgcagtat ggatttatcg ttcgttatcc
    11341 aaaaggacac gaagatataa ctaagatcac atatgaacct tggcacttac gttatgtcgg
    11401 taaagaaaac gctgagtata tcaccaaaca ccaattgacg ctagaagaat atctgaatga
    11461 attaaatgaa aagtaggaat tgatcatggc gaaaaaaaag tggaaaaagc aaaagcgcaa
    11521 gaatatccgt tggccagcag tggttgccgg tgtagcagtg atactcttag cctttgtttt
    11581 ttccttgaag aatctgtctt ctccttttac tgataatcag caagaaaatg aagcgcaatc
    11641 ccatcagcaa tttattgaac ggcttgttcc gcatgcccaa gaactacaag atggttatgg
    11701 agtgcttcct agtatcattt taggacaagc tatattagaa tcaaattggg gaaaaagtac
    11761 cttggctagc aaatacaata atcttttcgg gatcaaggct tatggggatc agaagaaagt
    11821 aagcctggaa acaaaggaat ttgttaacga agaatggata actatccaag gagacttcaa
    11881 agtgtatgat tcatgggaac agtccatgga tgaccataca caactgttcg tccaaggagt
    11941 agattggaat cctgcgctgt atgaaaaagt gattacggcc accaactatc aggaagccgc
    12001 acaagcattg caagatgcag gttatgcgac agaccccggt tatgcgcaaa aaatcatcca
    12061 ggtcatcgag acgtatcaat tgaatcagta tgaccggaga tagcaaagga gaagtggctg
    12121 atggcagaac aatttacgcc agaaatcatg acggaattga gaaaagatat cgtaagagta
    12181 ccggaaatca ttttagaagc aagcgggatc aagatatttg gaaaattgat ccgttcgatc
    12241 atctttacta cggatattgc gatcatacgt aatacaaatg cgaatgcagt aattgctgtg
    12301 tatcctttta cacctcatcc agcgattact aaaagcatta ttgaggcagc tgacattcca
    12361 gttttctccg gtgtaggtgg tggtttgaca caaggtgctc gttcttccta catgagcatg
    12421 ttcgcagaag cgcaaggttc gttaggggtc gttttgaacg gtcctacgcc tttagagaca
    12481 gtaaaagaag tttgtcgagt agttgatatt ccagttatca gtacggtaac gtcgaaatat
    12541 acagaaatag atgaaaagtt agcagctggt atttcgatta tcaatatcag tgcaggtaaa
    12601 gaaactgcag aagcagtacg ccattttcgt aaaaaatatc ctgaacttcc tatcattgcg
    12661 acaggtggtc caacggaaga aagtattgct gagaccattc aagcaggagc aaatgccatc
    12721 acatatacgc caccaagtag cggagagctt tttagtcgta aaatggaaaa atatcgggaa
    12781 actgagaaaa agaatcatga ataacaggtg agaatcaaaa gacgaggaag agcagatagt
    12841 ggctcttcct cgtcttttgt actccagtac tatttgttca gaattcaaaa aaaagagaaa
    12901 tttttttgtt tttttacctg taatgtacat aagaagagtt aaaacctttt gttattatta
    12961 gcattctaac aaaaaaatgt cttgatttat tgaagcgctt tctatagaat gaaaaacgaa
    13021 taaaaactaa aaaaggcacc cgacaattta gtagcagcta aattgtcggg gcttgaaaag
    13081 tcagcgggaa ctgaccaatc aagttgccat agtcaatgct tgtgcatcga cgtgtatatt
    13141 gtacctaatt tcatacagaa ttactagtta tttttctgtt ttttagggaa gagcgcacac
    13201 gaagaagcat gcttatttag ctatgtcaag gatattgggc agttgtctga tatccttttt
    13261 tctttgcgta attatcctcc catcattgaa gcaagaagtg tttttagcga tgaaagaaga
    13321 atcagcacta tctaattttt cttgaaagta ttgagttgtt catcctaggc agaacgataa
    13381 ggcaagtctt ggtttttatt ccccttgaaa aagatcgttt aataaatatg ttctgtataa
    13441 aaatacagta tattgaaaaa taacaatgga agtagaggtg cagagaatga agaaaagaat
    13501 gagaatcatc ttagctttaa gtgttatgtt attcttcttg acggcttgtg ggcaagaaga
    13561 tgacaaaaaa atcacgctga acatggcttg gtggggttcg caagtccgac acgatgcaac
    13621 agtaaaagta atcgagcttt atgaagaaaa aaatccccat gtgacgatcg attatgaatt
    13681 ttatgattat gaaggatatt acacaaaatt aggtacacta gcagcatcag atgatatctg
    13741 ggacattttc caactgaaca atcaatttcc tcaatacatc aatcagattg aaccattaga
    13801 tgaatatgtg gagcaaggga taattgatat ttctaatgca gatgaatcct atttagcaac
    13861 gacgacttac gacgggcaat tagttggact gtctaacggg gtgaattcgt ttgcgattgc
    13921 ttacaataaa aatatatttg aacaattaaa tatccctgaa ccagcttcaa attggacatg
    13981 ggatgaattt gaacaaatca gctatcaaat cactgaagaa ttaggaatct atgctatttc
    14041 aagattcgaa gattttatag ctggctgtat tattcaaata ccacaagttg agaaaggatt
    14101 gaatttttat aatcgggaag atctatctaa cagcttggga tttgaaaatc cagactatct
    14161 aacagatttt ttccagctgc gtaaaaatct ggtagacaaa ggggcccatc cagaaccagg
    14221 tggtggagct gcaagtacga cggatctgtc ttttcaggcg gttagggata gagaagcggc
    14281 aatggtgttt ctatcaagta accagttgac agaaatattg tcaggggctc ctgaagatat
    14341 ggagattcag ttgattaatc cacctcgcag aaaagcagat ggagaatctg gtatcccttt
    14401 acgttcttcg caaatgctga gtatggcaaa aagctcagcc cataaagaag aagctgctaa
    14461 gtttattgat ttctttcaaa acagtgaaga agccaatgaa attttaaaag gagaacgtgg
    14521 tgtaccaatc atgtcgaata ttcgagaaca gctcgctcgt gcagatgatg caactttgca
    14581 agcgacattt gattatttag aaatgatttc cgatatggac aacggcgaag tgaatgtctt
    14641 tgatagtgct ttgaatccgg aaattcaaga ccaatacaat cttttagttg aaaaagtcat
    14701 ttatgaagaa gtaacagcag aagaagcagc agagagtctt tatgagtttg cgtcaaacat
    14761 tctaggatag cagcaggagg aaggcatgaa aaaagaaaaa ctaaaacggt tcttggatca
    14821 agacaatgtg gtcggttacg tatttgcttc tccattcatc ctaggatttc tattgataac
    14881 agtgataccg atgatcttgt cactttatta ttcgttcacc gattatcgtt tgggaaatcc
    14941 agtctcatgg atcggcttgg ataattatat aaagatgctg agtgatgccc gttttttgaa
    15001 ctccatccga gtcacttttc tctatgtatt tgcatctgta cctgtgaaac tgatctttgg
    15061 tctattgatt gcttatcttt taacgaggaa tatcaaagga acgactttct ttcgttcttt
    15121 gtattatgtg cctagtttga tcggtggcag tatttctatc gctctagttt ggcgggagtt
    15181 gttttctaaa aacgggttag tgaatatttt cctggaacga ttaggcgcac ctgcgctttc
    15241 ctggtttagc gatcaaaaac tggtcatgat ccctcttgtt ttgatgtctg cttggcaatt
    15301 cggttcggca atgatcatct ttgctgcagg tatcaaagag atcccaggct cgtattatga
    15361 agcggcagag atcgatggag cgaacaaatg gcagacgttt tacaagatca cgttacctct
    15421 tctttcgccg atcattttgt ataacttggt tatgcagaca atcgcggcgt ttatgacttt
    15481 tacgcaggca tttatcatta cccaaggtgg tccgaatgat gccacgaact tttatgctct
    15541 ttatgtgtat aaccaagctt tttcttttaa ttctatgggg tatgctagtg ctatttcgtg
    15601 gatcatgctg ttgattatgg gagctgtcac ctttctgatt ttcaaatcat caaaaaaatg
    15661 ggtcgttgtg tgaatgagag gaggaagaaa tgaataatac agtaacgaaa tggtttcaat
    15721 acggttttat tttgctatta ggtctagtca tgatttatcc ggtcttatgg atgatcgcag
    15781 gttcttttaa aacggatcaa gagattatga gtggttcgct gaatttgatt ccagagactt
    15841 ttcaatggga aaattacgca aaaggatggg cggggtttgc tggaatttca ttttttactt
    15901 tctttaggaa ttcgtttgtc atctctgcag tttcgacgat agggacagtt ctgagctcga
    15961 cttgtattgc ttacgcatta tcgagaatcg atttcaaagg aaaaagattc tggttcgtcg
    16021 tcatgttagt aacgatgatg attcctgcac aagtgatttt gattccgcag tttattattt
    16081 acaatcggct gaatttggtt gggacgtatg tgccgctgat tttaccacat ttttttggac
    16141 aagcattttt catttaccag atcatgcaat tcatggtcag catccccaaa gagttagatg
    16201 aatcagcgat tattgacgga tgcagcaagt atagtgtctt taccaaaatt atttttcctt
    16261 tgctgaaacc ttcgatcatc acgacgatca tcatccagtt ttattggaaa tgggacgact
    16321 tcatgggacc attgatttat ttaaacaagc cgagatctta cacggtatcg attgccatca
    16381 aattatttgc agacgctgga tctagtacga cttacgcgag tatgtttgcg atgtctacgt
    16441 tgtcgctgct accggttttt ctgattttct tattcttcaa taaatatctt gtccagggga
    16501 tcagtacaag cggtctgaag ggctgaatat gaaaaagcca atagaagaga tgtttcttta
    16561 caagctcaac tactatgtct gtcggatttt tttaaccagt cttatcagta atgctctttt
    16621 cgctttagtt ctaggatgtt tgttcacttt aggattagtg ctgtctgctc gtgttgtcta
    16681 tctgatttat tttttgatga tgtatccttc ttattatcta tctgtccatt acttggcaga
    16741 aaaaaaggta tgttggagga aaggaaaaat caaacggatg tgtttcatca ttacgttgtt
    16801 tcagctgttt gtcattattt ttgcagttga ttggtattta ttagtgggaa agattggagc
    16861 ttggtatctg attccttttc tattgtgtct gttgcttttt gtatcccata gtttttttag
    16921 tacgctaatt gatatctgca aagaagataa agcagatagt cttgtttatt tgatcaaaag
    16981 gaatatctgg ctgttgtcaa aaaacgtcaa ggggtttctg tggtatttat gccttttgta
    17041 tggactgttc tggtgtatac agcatgattt tttactcact gcattactgt atccagggct
    17101 gccatttgtc acagtatttt gcttaaaaga aaaggagaat gactttaaat gaagaaaaaa
    17161 tatgtacaag tcggacttgg tgggagagcg cgtttttttt atgaggcaat tgcctctacg
    17221 tatcatcaaa cttgtgaact agtcggtttt tgtgatgtat ctcaaacaag gatggattat
    17281 gcaaatcgga tacttgtgaa caagtatgga cagaaaaaag taaagacatg tatgccatca
    17341 caatttgagc aactactgga tgacgtacgg ccggctgaag tcattattac gtcagtagat
    17401 cgaacgcatc atgattatat cattcgtgca atgaaaaaag gatatgatgt tatttgcgaa
    17461 aaacctctga ctatcgatga ggaaaaagct caagaaataa taacggtcca aaaacagacg
    17521 ggaagaagcc tgcgagtcac ttttaattat cgttatgcac cgtatcacac gaagataaag
    17581 gaactgatag aaagtgatgt gattggtgat gtgttttcta tccacttcga atggctgtta
    17641 aatacgcaac acggggcaga ttatttcaga agatggcatc gaaataagca caatagcggc
    17701 gggcttcttg ttcataaatc tacccatcat tttgatctag tgaatttttg gttgaacagc
    17761 cgtccccaaa aggtatttgc attcggtgga ttaaactttt atgggatgca taatgcggag
    17821 aaacgcggag tagaaatatt ttacagtcga tgctatggaa gcgaactagc taaagctgat
    17881 ccatttgcta tagacctgtc agccaatgag gaattgcgag aaatgtattt agaagcagaa
    17941 aaagacagtg gatatattcg tgaccgcagt gtattttccg atgatatctc tattgaagat
    18001 acactaggcg taacggtcaa atatgaaact ggtgcgattt tgacgtattc gctaaacgcg
    18061 tatatgccgt gggaaggatt caatgtttct ttcaatggca gcaaaggacg gatcgaaatg
    18121 aaagtgatcg aaaagtctta catcaatgca ggtggagata aaaaggatga aggagcagcc
    18181 gttcttcagt ccatccatgt ctatccgatg ttcggtgagc catatgaggt aatcgtcgaa
    18241 caagaagcgg gcggacatgg cggaggagat ccgcgtttat tagatgatct atttggtgaa
    18301 gaaaaagaag aagatccgtg gaatcgggca gcaactcacg tagatggtat tttgtcgatt
    18361 ttgacaggaa tcgcagcaaa tcattctatt gcttcaggaa aagcagtagt gattgacgag
    18421 cttgtcagct taaaagaata agaatagatt tacggaaatt acttcccgta gtttataaaa
    18481 tcttgcctta ttgccgatag gctgtctttt gaacactatt tattcggaaa aaggggctat
    18541 gacatgcttt ttgtcatgcc ttctttttat gtgggctgct tttttagata ggagaaaata
    18601 aaaataacta tttaaacccg aacaaaaagg aataatgcat taaaaatcat tagattttac
    18661 aaaaaaataa gtaaaccacg ttgtcagttt cagaaagtag tgttagactg ttttcaatat
    18721 ttgaaacaac attttttatt caaatatggc aaactgcctt cacgtgcaaa acagttgcaa
    18781 gaaaatgaat ttacactatt attagtttta catacctact tatatatcgt cataatatgg
    18841 atgacagttt ctagccagta ccgtaaatgc tggactataa gtaaaagatt ggctatttca
    18901 cccttctttt cttatgataa agtggagggt gtttttcttt aacagaaaca tagtaggttt
    18961 ttgcacaaaa gcggttattt cggtattaat aaatgataaa ggagcaaata aagtgaaaga
    19021 attagttgaa cgtattcaaa aagacggacg tatattaggc gagggcgtat taaaagtcga
    19081 cagcttcgtc actcaccaag tagaccctgt attgatggaa caaatgggaa aacggtttgc
    19141 agaagtattt aaagaacaag gaatcacgaa agttgtgacc attgaagctt ctgggatcgc
    19201 accagcttta tttgctgcaa gagaattaga tgttccaatg atcttcgcta gaaaagcaaa
    19261 aagtttgacg atggatgaag aattattgac agcttctgtt tattctttta cgaaacaagt
    19321 gacaagtacg atttctattt ctcgtaaatt tttatcttca gaagacaaag tattgattat
    19381 cgacgatttc ttggcaaacg gacaagcggc aaaaggattg atcgaattat gccagcaagc
    19441 tggagcgcaa gtagaaggaa tcgggatcgt catcgaaaag tctttccaag atggacgtca
    19501 gttacttgaa gaaatgggat tgagagtcgt ttctcttgcg cgtattgctt ccttgacgaa
    19561 tggacaagtt gagtttcttg aggaggacgc ataatcgtgg aaaaagaaac acaaaatgga
    19621 aaagctgcgg ttttagggct gcagcatctg ctagcgatgt atgcaggagc agtagcggtg
    19681 cctcttttga tcggtacagg actaggcttt aatcaagaac agatgactta tttgatttca
    19741 attgatatct ttatgtgtgg attagcgaca ttattgcaat tgacagttaa ccgatttttc
    19801 ggaattggct tgcctgtcgt tttaggatgt gcgatccaag cagtagctcc actgatcttg
    19861 atcggaacca atgaaggagt aggagctatc tacggatcta ttatcgcttc tgggatcttt
    19921 gttgtgttag tttctggtgt cttttctaaa attaaaaaac tattccctcc tatagtaaca
    19981 ggaacggtta tcaccgttat tggtttgact ttgattcctg tagcaatcga gaaaatgggt
    20041 ggaggtaatg caacagcagc tgattttggt gacaaaacaa atctgctact tgcatttgtg
    20101 acgattctcc taattgtagg cgtgcaaatg ctggcaaaag ggttcattcg ttcaatcgcg
    20161 gtattgattg gtttagtcgg aggaagcatc ttagctgctt tcatgggaat gattgatctg
    20221 agcgcgattg gagatgcgcc gttgttccat gttccacaac ccttttattt tggtaaacca
    20281 actttcgacg tatggtcgat tttactaatg atcatcattt ccatggtcag catggtagaa
    20341 tcaacaggtg tatattttgc acttggtgac attactggga aaaatgttgg agaagaagaa
    20401 ttgaaaaagg gatatcgtgc agaaggactt gccgttatct taggcggtat tttcaataca
    20461 ttcccttata ctggcttttc tcaaaatgtc ggattggttc aactttcggg aatcaaaaca
    20521 agaaaaccca tctatttctc tgcattcttc ttgattgttt taggattatt ccctaaaatc
    20581 ggtgcgttag cacaaatcat ccctgagccg gtacttggtg gaggaatgtt agtcatgttc
    20641 gggatggtgg cagtccaagg aatccgtatg ctgttggaag ttgatttcag caatgataaa
    20701 aatctattga ttgttgctgt ttctgttgga tttgggctgg gtttcaatgt tacgccgaca
    20761 ttattcagtc aaatgccgca aacattgcaa atgttcactg gaaatggcat cgtaatgagt
    20821 agcattacgg ctatcatatt gaatttgatc tttaatggat tgaaaaaaga tgaagaaata
    20881 ttggaagaag ccttcaagaa gtaatagagc aaaagaaagg ttgtgaaatc agcgttttga
    20941 cctgattgtt agagaaacaa acggaaaaat agttcctcgt attttgccgt ttgtttgagc
    21001 taataccgag ggtcagctga ttgaacaccg ttgaaggaag aggtcgtgag cctgccgttc
    21061 atctccgagt cacaaggaac aatttcaaaa aaaagcttct catgtttgtt gaatattgtt
    21121 ccttgtgacc gaggagttgg caggagaaca ccgtttatcc ataaaaagga atgtgaccta
    21181 acttttgtca cattcctttt ttttatcttt aataaacacg aacaataaaa tgtttttctt
    21241 tgttaacatt cgaaatttct ttgacatcaa aaaaagtgat tgttaaaata tgaatgtaga
    21301 aaaactggga ggaaaaacaa tgacagcaaa aatctctgtg attatgggga gtacttcaga
    21361 ttgggaaaca atgaaagaag catgtcaaat attggatgaa ttcggtgtgt cttatgaaaa
    21421 aaaggtcgtt tctgctcatc gaaccccaga tttgatgttt gaatatgcac aaaacgctcg
    21481 aaaaaaagga atcaaaatca ttattgcagg agcaggggga gccgcgcatc tgccgggtat
    21541 ggtcgcatca aaaacaactt tgccggttat cggtgtaccg gtccaatcac gaacattaaa
    21601 tggtttggat tcgcttcttt cgattgtcca aatgcctgga ggagtacctg tagctactac
    21661 agcaatcgga aaagcgggag caattaatgc tggactactt gcgatacaga tgctttccat
    21721 gtatgattta gaattggagg ctaaattggc tgaaagacgt tcaatgttgg ctaaaactgt
    21781 tatagaaagt agtgatcaac ttggttaaac ctttgttgcc tggttcaacg atcgggatcg
    21841 tcggtggcgg tcaattaggt cgtatgatgg cgattagtgc aaaagaaatg ggctttaaag
    21901 taggtgtgct ggatcctgtg agcgattgtc cagccgcaca agttgcagat tggcatattg
    21961 aaagtgtcta tgatgacacc tttgcgctga aagagcttgc cagaagaaca gatgtcatta
    22021 cctatgaatt cgaaaacgtc agtgtagagg cgttaaatgc gattttaccc atgtcattta
    22081 ttcctcaagg gacagacttg cttgcgatta cgcaagaccg cctgttagaa aaatcttttt
    22141 tggaaacgaa taacatcgtg attgctcctt atgcaacgat cgtcagtccg acggatatcc
    22201 aagatgcgat tgacgggatc ggctatcctt gtgttttgaa aaccactcga ggcggctatg
    22261 atggcaaggg gcagtatgtt ttgaaaagtc gggcggatct agctcctgcc atggaccttt
    22321 taagagaagg aacctgtgtt ttagaagcat ggatcccgtt tgaaaaagag atttcgatca
    22381 tggtggcagg aaatggtcaa ggagatttca cgacttttcc ggtcgtggaa aacatccacc
    22441 acaacaatat tcttcatgaa acgattgctc cagccgcgat tgatcaggat gtgatcgagg
    22501 aggctgagcg tattgcccgt gtgattgcag aagcagtgag cctttcaggt gttttagggg
    22561 tagaaatgtt tttaacaaaa acaggcgggc tatatgtgaa tgaattagct cctcgtcctc
    22621 acaattctgg acattattct attgaagctt gttctatgag tcagttcgat gcccatattc
    22681 gaggtatttg tggttggcca ttaggagaaa aagtacgttt gataagcaat gcagtaatgg
    22741 tcaatgtttt gggagaacaa ctgctggaaa gctatcgctt gattgagaat aagccagact
    22801 ggcaattcca tttctatgga aaaaaacaag caaaaaaagg tcgcaagatg ggacatatca
    22861 ctatcttgac agaagacatc cagcaaacgc tggaagaaat caaacaaacg aatatttggg
    22921 attagaggag aaaaaacatg ttagaacgtt atacacgccc tgaaatgggg aatatctgga
    22981 cggaagagaa caaataccgt gcgtggctcg aagtcgagat tttagcagat gaagcttggg
    23041 cagaacttgg tgaaatcccg caagaagatg tgaaaaaaat tcgtgagcat gcatcatttg
    23101 atatcgatcg gatcttggaa atcgaaaaat taacacgcca tgatgtcgtt gcgtttacac
    23161 gagcggtttc tgaaacattg ggagaagaaa gaaaatgggt ccattatggt ctaacaagta
    23221 cggatgtcgt agatactgct tatggctatc tcatcaagca agcaaatgat attttacggg
    23281 aagacttgaa acgttttacg gaaatcattg gcgaaaaagc aaaagaacac aaatatacag
    23341 tgatgatggg tcggacacac ggtgtccatg ctgaaccaac tacttttgga ttgaaacttg
    23401 ccacatggta ttcagaaatg aaacggaaca tcgaacgatt tgaacatgcg gcaaaaggag
    23461 tagaagcagg aaaaatctca ggagcagtgg gaacgttcgc aaatatcccg ccatttattg
    23521 aagagtatgt atgtaaacaa ttggggatcc gtccacaaga aatttctact caagttctcc
    23581 ctcgggatct acatgctgaa tatttctcag cgatggcgct tattgctaca agtattgaac
    23641 gttttgcaac agagatacgc ggattgcaaa aatccgaaac acgtgaagta gaagaatttt
    23701 ttgcgaaagg tcaaaaaggt tcttctgcta tgccgcacaa aaggaatccg atcggttcag
    23761 aaaatatggc tggtctagcc agagtggtgc gcggacacat ggtcactgcc tatgaaaatg
    23821 tcacattatg gcatgaaaga gatatttctc attcttcagc agaacgaatc atcttgcctg
    23881 ataccacgat tttattgaat tacatgttaa atcgttttgg caatatcgtt aaaaatctaa
    23941 cggtctttcc tgaaaacatg aagcggaata tgtctgcaac atttggtttg atttatagcc
    24001 agcgcgttat gctgaaattg atcgataagg gaatgacaag agaagaagct tatgatcttg
    24061 ttcagccaaa aactgcgtac gcttgggaca accaagtgca gttccgcccg ctgttagaag
    24121 aagatccaac catcacatcg gtattatcta aagaagaaat agacgatgcc tttgattatc
    24181 atcatcattt gaaaaacgtt gacgtgatat tcaaacgagt aggtttggaa taaagaagag
    24241 tgagttgcaa aattcaatta aaatagaata gcaaaaataa ccaaaaaaga agcagatccg
    24301 ttagcggttc tgcttctttt agtttattat attttcttat caataatagg aacctgattt
    24361 taaaagcggc tacctcttta ccgtgcctct ttacatacaa aaaatagagg aattaagcgt
    24421 aaatggcttg gctattataa ctaaaatgct ggttatggag atgttgcagc aagttttcga
    24481 gaaaagcgta ttccatctct tgtccattga ataagatctg gatacgataa tgatttttga
    24541 aacgcttctg ttcatgaatc tgactgattg aaagttcgcc tttgtgttct gtctgataaa
    24601 gaaaagtcct tttacggcat tcagcacagc gcttggttgc tcggcggatt tttcggaatg
    24661 tataaaaact agtatcttta ttgcataaat aaacgtcttt gatcgacagc aaatcattat
    24721 atagacagga acgttcttca gctgttaatt ctgataaaaa aagctgacct tgttttattg
    24781 catcttccat cggcaagtgc ctcctcgaac ccattaacca aatttttagt taattctaat
    24841 ataccatcat taagtataaa tgtaaacgct tgttgatggt ataagatttt cgtttctgat
    24901 aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac atatttttgt tgatttataa
    24961 aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta
    25021 atgtaaataa aaaggagaga cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc
    25081 caaaaaaata tatcttactt ctgatgagaa cttgatttgg atagaatatt tagatcaagc
    25141 aactgcgttg aatggcgcga ggaaagacca gataagtgga aaaggagaat tgaataatca
    25201 aatcacaagt gcaattttcc gttatctgac tcaaagagga ataaaaaatc attttattga
    25261 acaattgtct aaaaccgaac aattagcaaa aaaagtacaa attatccctc tggaagtggt
    25321 tatccgaaat attgcagcag gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga
    25381 attcatcaaa ccaatcattg aattctacta taaggatgac cagttggatg atccatttat
    25441 caatgaagag catatctatt tcttacaact tgcaaagccg gaagaaatca gtgagctgaa
    25501 agcccaagcg ttggctatta atgaaatttt gaccgaatta tttgctaagg tcggtttggt
    25561 tttagtagat ttcaagctag aatttggccg gtcgaatgga caaattttgc ttgcggatga
    25621 agtaacaccg gatacttgcc gattatggga tgaacgtacg aatgaacata tggacaaaga
    25681 cgtttaccgc agagatctag gtgatttgat cccagtctat caagaagtat ataaccgtct
    25741 atcggaacta actgaagaaa aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc
    25801 tataaagatt cagtgttaga tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg
    25861 ggatatgaaa caatcgaaga tatccgaata ggaaaatact ttgagataca acttgctgat
    25921 gcagaagaac caatcgatac agtgattgaa acgatttgtg acaagctgct tgcaaatgta
    25981 aatatggaaa cataccgata tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc
    26041 ggtcatcgtt tttccaggtt caaattgtga cgcagatatg ttatgggcag ttcgcgagat
    26101 catgggcgct gatgccgaat ttgtacggca tgatgagtcc tctttagaag gatttgatgg
    26161 ggttttactg ccgggaggat tctcctatgg tgactatttg agatgcggtg cgattgctcg
    26221 gttttctaca atcatggaag aagtgattcg ttttgctgaa gaagggaaac cagtattcgg
    26281 tacatgcaat ggattccaga tattgacaga agcaggactt ttgccaggtg tactgagacg
    26341 aaatgagtct ttgcatttta tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc
    26401 ctttacttca gagtatgaag ccgacgaaat aatctatctt ccagttgctc atggggaagg
    26461 aaattatttc tgtgacgaag aaacacttca agaactaaaa aaaaataatc agattgcctt
    26521 tacttataat gacaacatca acggcagcgt ggaaaacatt gcagggatta cgaacaaagc
    26581 agggaatgtg ttaggaatga tgcctcatcc agaacgtgca gtagaagact tgctaggatc
    26641 agaagatggg aaacggttct ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata
    26701 gatgaaaaca ttgaaagaac cgacagctga agagatcaag aaaaaaagaa tctatgccga
    26761 atggggattg actgatgaag aatatcgaat gatcgaagaa gatatcttag gaagaatgcc
    26821 taattatacg gaaactggac tgttttctgt tatgtggagc gaacattgtt cctataaaaa
    26881 ttctaaaccg gttctacgca aatttcctac tagtggacct catgtgttgc aaggccctgg
    26941 agaaggcgca ggcatcgtcg acatcggtga tggactagca gttgtcttca aagcagaaag
    27001 tcacaatcat ccttcagccg tggagcctta tgaaggagct gcgacaggag ttggcggaat
    27061 catcagagat attttcagca tgggggctcg tccaattgcg ttgctagatt cattgaggtt
    27121 cggcgaatta gataatccaa gaacgaaata tttactagaa gaagtagttg caggtatcgg
    27181 cggatacggc aattgtatcg gcataccgac tgtaggcggc gaaattgcat ttgatccttg
    27241 ttatgaagga aacccattag tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat
    27301 ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg
    27361 tcgcgacggt atccacggag caacttttgc ctcagaagaa tttaatcaag aagaagaaca
    27421 gcaacgttct gctgtacaag taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg
    27481 tttggaatta atcttgcatc attcggattc tctaataggt atacaggata tgggagcagc
    27541 aggacttgtt tcatctagtg cggaaatggc ttcaaaagct ggctcaggac ttatattgac
    27601 attagatgaa gtcccacaaa gagaaactgg gatgacacct tatgaaatga tgttatcgga
    27661 atcacaagaa cggatgttga tttgtgttaa atcaggagag gaagaaaaaa tccaagaact
    27721 atttcagaag tatgatctag atgcagtcac tatcggtaaa gtaacagacg acgggcaata
    27781 tcggctatat catcaaggag aagaagtagc aaatctgcca gtcgatgcat tagctgaaga
    27841 tgcaccagtt tatcataaag aaatgaaaga accagctcga atcgtagaat ttcagcagtt
    27901 agctccttat cagccagtta tcgaagaacc tggacaagta ttgcttgatc tgctgcagca
    27961 accgacgatt gcttcaaaac gttcaatcta cgaaacttat gattcacaag tacaaaccaa
    28021 tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg gttagaggga cgaataaagc
    28081 gttagctatg accacagact gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg
    28141 acaaatagca gtggcagaag ctgctagaaa tattattgct agcggtggta agcccttggc
    28201 gatcaccgac tgcctgaact atggttctcc tgataaacca gaagtttttt gggaattatc
    28261 gacttcagct gacggaattg ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg
    28321 aaatgtctct ttatataatg aaacggatgg tcaagcaatc tatccaacac caatgattgg
    28381 tatggtcgga ttgattgagg atcataaaca tatcactact caggaattca aaaaatcagg
    28441 ggatctaatc tatatattag gtaagacgtt tgcagatttt gatggcagtg aattacaaaa
    28501 gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag
    28561 aaaccaagag ttagtattga cagccatcca aaacggattg attgaaagtg ctcatgactg
    28621 ttcagaaggt ggcttggcaa ttgcactggc agaatcagct ttcaaacatc agctagggat
    28681 atctgtacag tttgaattgt cctctgctca attatttgca gaaactcaat caagatttgt
    28741 gttgacagtc gcaccggaaa ataagacacg attcgaagaa atgatgggag atgctgctgt
    28801 tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt tcagcaactg acggtcagat
    28861 caaaatagaa actgcagtag caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa
    28921 gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt ggggtcatcc agacgccgct
    28981 agtgtggcat acttcgggct ccatagtctt cagcatcgag gacaagaagg tgcaggtatc
    29041 gtgtccaatg atcgaggaaa gcttaagggg catcgagatt tggggctgct ttctgaggta
    29101 ttcaaagatc aaagaaaatt gcagcagtta acaggagaag ctgcaatcgg acatgtacgt
    29161 tatgcaacag caggcaatgg aagtgtggac aatattcagc cttttctatt caaatttcat
    29221 gatcagtcga tcggcttagc gcataatggt aacttgatca atgctcgttc ccttagaaaa
    29281 gagttagagg aaaatggggc gatcttccat tctaactccg atacggagat attgatgcat
    29341 ttgatccgac gaagtgaaga aacagatttt ttaaataaat taaaaagtgc tttgaatgaa
    29401 gtcaaaggtg gctttgccta tttattaatg acagaaacgg caatgattgc cgctttggac
    29461 ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa acggagcata cgtgattgcc
    29521 tcggaaactt gtgcattaga agttattggg gcacgtttta taagagatgt ccagcctggt
    29581 gagatagtga tcatcaatga cgaaggaatc cagattgatt gctttacgaa ggacacgcag
    29641 ctttctattt gttcgatgga atatatctat tttgccagac cagattcaaa catcgcaggg
    29701 atcaatgtgc atactgcacg gaaaaatatg ggacggaatt tagcgaaaga atcgccagta
    29761 aaagcagata tggtcgttgg cgtacctaat tcttctttgt cagccgcaag cggttatgcg
    29821 gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca
    29881 tttatccagc caacgcctga gctaagagag caaggtgttc gaatgaaatt atctgctgta
    29941 cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg attcaattgt tcggggtacg
    30001 acaagcagac ggatcgtcca tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg
    30061 attgcttctc ctcctttgaa atatccatgt ttttacggga ttgatattca aacgcgtaaa
    30121 gaactcattg cggcaaatca cacgattgat gaaatcaaag aatgtatcgg tgcagattct
    30181 ttaggttttt taagtgaaga gggtctgatc gaatcgatcg gtctggaaaa agatgctccg
    30241 tattcaggat tgtgtatggc ttatttcaac ggagattatc cgacgccgtt atatgactat
    30301 gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag
    30361 aagggagtat atgaattcaa tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc
    30421 tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat
    30481 gatgggcgct ataggaggat tcggcggttg ttttgattta tcggtctttc aattaaaaga
    30541 gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa ttagcagtgg caatcgaagc
    30601 agacaaacac gatacaatcg ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc
    30661 acaaggcgca gagccgttat atttcttaga ctacttagca acggggaaaa atgatccgtt
    30721 acgtttggaa aatgtagtaa aaggtgtagc agatggatgt gttcaaggaa atatggcgct
    30781 gattggcgga gaaacagctg aaatgcctgg tatgtactca ggtaatgatt atgatctagc
    30841 cggatttgct gtagggatag ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc
    30901 aggagatgtg ttgcttggaa tagcatctag cgggattcat tcaaatgggt actctcttgt
    30961 tcgcaaaatt ttctttgagc agcagcagtt ttctttatca tcaaaactgc cagaattgaa
    31021 aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc
    31081 gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc actggtggag ggtttgtaga
    31141 aaatatcccg cgaatgttac cagaatctat ggctgcacaa atcaaacttg gctcatggcc
    31201 gattcttcca atattcggct gtttacaaaa atatggtgaa attcctgaga tggagatgta
    31261 tgaaatcttc aatatgggca tcggtatggt cctggcagtc gaagaatcga aagtaaaaga
    31321 aatagtacac gaaattgagc aagctggcga aaaagtttat gaaatcggga aagtgatcgc
    31381 caaagaaaaa catcgtgtgg tgtttatagg agaagaacga tgagaatcgc tgtttttgct
    31441 tctggaaacg gaagcaactt tcaagcgcta gccgattatc tatcgaaaaa aggattggaa
    31501 tcttcgattg actggttgtt ttgtgatcag cctgaagcat atgttttgaa acgtgcaact
    31561 gcgttgagtg taccggcaga ttgtttttca cctaaagaat ttgattcaaa aaaagagtat
    31621 gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg atttgatcgt attagctgga
    31681 tatatgcgaa tcattggacc ggtattgctg aaaaattatg ataaaagaat catcaatatc
    31741 catccgtctc ttttacctgc cttccctggt ttgcatggca tacgtgatgc ctttgaagct
    31801 ggagtaaaag aaacgggtgt cacaattcat tatatcgacc aaggtgtaga tactggacca
    31861 atcatccggc aggaaaaagt gagaattgaa caggaggaca cgttcgattc tttagaagaa
    31921 aaaatccata gagtagagca tcgaatctat ccagaagtga ttagtgaaat tattgaaaat
    31981 ggaggctatc tgaaatgaca agagcattga tcagtgtatc agataaaact gggattgtag
    32041 cattcgccca aggtttgatt gaacaaggag tagaaatcat ttcaacagga ggaacaaagc
    32101 atgcgttgga taaagctggg atcaaaacgc tttcgatcga agaagtgaca gggtttcctg
    32161 aaatgatgga tggccgtgtc aaaacacttc atcctaaaat ccatggtggt cttttaggaa
    32221 gacgcgatct ccctagccat atggaggcaa tggaaacgga aaatatccaa ccaatcgact
    32281 ttgtttgtgt caatttatat cctttcaaag aaacgattat gaaaccagat gtcgaaatag
    32341 cagaagctat tgaaaacatt gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa
    32401 accatgaatt tgtcacctct gttgttgatc catctgacta tgaagaagta ctttcagaat
    32461 tacgtcagta tgggcatact tcactttctt tcagacaaaa actagcggca aaagtctttc
    32521 gtcatactgc ggcatatgat gcactgatcg ctcaatactt aacggattgg gtggaagaaa
    32581 aagaaccgga aaaattgaca cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa
    32641 atagccatca agccgctgcc ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag
    32701 cagcaaaaca actccatggg aaagaacttt cttataataa tatccgagat gcagatgctg
    32761 cgctacggat catgaaggaa tatgacgagc caacggtagt cgccttgaaa cacatgaatc
    32821 cttgtggtat tgggacagca tctacgattt tagaagcgtg ggaagcagcg tatgaagcag
    32881 atcctgtttc aatctttggt gggatcatcg ttttgaatcg agaagtagat ctgccaacag
    32941 cagaacagat gcataagctg tttctagaaa tcatcattgc cccttcttat acacaagaag
    33001 ctttggaatt actgcaaaaa aagaaaaaca tccgattact gacagtagac tttgcgcagg
    33061 aagaaaatca aaatcgagaa gaaacggtct cagtcttagg tggacttctt gtacaagatc
    33121 aagatctggc aatagaaaat gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc
    33181 cagcagaagc aaaagcatta gtgtttgctt ggagagctgt caaacatgtg aaatctaatg
    33241 cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg agccgggcag atgaatcgag
    33301 tcggttcagt aaaaattgcg attgaacaag cgcaagagaa aatggaaggt gcagttttag
    33361 ctagcgatgc ttattttcca atggatgatt cggttgaata tgcagccaaa catggtataa
    33421 aagcaatcat tcagccagga ggaagcatca aagaccaaga ttctattgat atggcgaata
    33481 aatacgatct agcaatggtc tttactgatg ttcggcattt tagacattag agaggagtcg
    33541 gataaatgaa cattttggtg atcggtgcag gtggtcgtga acatgcaata agtaaaaaac
    33601 ttttagccag tccgaaggtg gatacggtgt attgtgcgcc aggaaatccg gggatgacaa
    33661 aagatggtat caattgtgtc gctatcagtg agcgagatca ttcagcgtta atccattttg
    33721 ttaagaaaga ggctattgat tggagtatcg ttggtcctga agttcctttg ttaaatggga
    33781 tcgtcgatga ttttatggcg gaaggattga aaatcttcgg tccgacaaaa gcagcagctc
    33841 tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga tacttatcaa atcccgacag
    33901 ctaaatccag aagttttgaa tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg
    33961 cgccaatcgt agtgaaagcg gacggcttag cagctgggaa aggtgtagtc gtggctacca
    34021 cagtgaagga agcgctggat gcggcagaac aaatgttgaa ccagcatcga tttggggata
    34081 gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga agaattctcc cttttggcgt
    34141 ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca agatcataag cgggcatttg
    34201 ataacgataa agggccaaat acaggcggaa tgggtgctta ttcaccagta ccgcaaattt
    34261 caaaaaagat gattgaaaaa gctgtggaag aagttttaaa accagcggct ttgggaatga
    34321 aagaactagg acgctctttc acgggtgttt tatatgcggg tttgattgct acgaaggaag
    34381 gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt
    34441 ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt attagagaat cgtacagtag
    34501 agttaaagtg gcagcaagaa ggatacaatg taggcgttgt ggttgcagct gccggttacc
    34561 ccgaagaata tgagacagga atggttctac cagattttct ggaagaagag ctttctgttt
    34621 actatgctgg agtttcctca aataacggca aactagttgg agcaggagga cgtctttatt
    34681 tagtagaagc atacggtgag acgatcaaag aagcacagaa aaaaatttac accgcgttaa
    34741 tggataaaac gacagatgga acattttatc gtacagatat tggagaaaaa gctgccaata
    34801 gcgaactgat cgtgaagtaa atcagctgct tccatttata aaaaatacaa caaacataat
    34861 cggaagcgcc gattttagtg aagccttttc ataaagagtg tggtacactt ttgttgtgta
    34921 tataaataag gaggagttca gatgaaaaaa attcaattag gtacttctga tcagaaagca
    34981 gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt
    35041 gagacagctt atgaaaacgg cattgatttt tttgaccatg cagatattta tggaaacggt
    35101 gaatgtgaag aaatctttgc agatgctcta gcaaaaacat caatcaaacg agaagatctt
    35161 tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat
    35221 atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa tggattatgt ggatgcttta
    35281 cttcttcatc gtccagatac attggtagaa ccagaggaag tagctgaagc gtttgatgaa
    35341 ttggaacggt caggaaaagt tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc
    35401 gaattgctga aaaaatatgt tcgtcaacca ttagtagcta atcagctgca atttggcttg
    35461 aaacatactg gaatgatcga tcaagggatt catgtcaata tgacagatga agcaagtatc
    35521 gatcatgacg gtagtgtact tgattattcc cgattgcatg atatgacgat ccaagcatgg
    35581 tcaccatacc agtatggatt ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa
    35641 ttaaaccaaa cattagaaga actagcagct aaatatcaaa cgacaccaac tggcttggct
    35701 tctgcttgga ttttacgcca tccagccaat atgcaagtga tcgccggtac gatgaacgta
    35761 gggcgaatca aggaaatcgc tcaagcttca gaaattaata tgtctcggga agattggtac
    35821 gaattgtacc gtgctgctgg aaacatttta ccttaaagat tgtcataagc aggtcaaaag
    35881 ggctataaat taaaaagaca gaataacttg aaagctgttt tcagcttcga gatattctgt
    35941 ctttttttat tgcaaatgga aagagtatca ttgtacggat ttcgtttatt agttattttt
    36001 gtttttaagg aaaagctgtg tccgatattc ttttggagaa atcccttgtt ttttcttaaa
    36061 taaataactg aaatagttag ggtcattata accaatttca aaagcaatat ctgaaatacg
    36121 atagtctgat tgctgcaata atttttttgc taattcgatt ctttgttctg tcagataatc
    36181 gatgaatgtt tggttaaacg attgagaaaa aatcgtactg aaatgagagg gacttaatgc
    36241 aacttgttga gcgacccaag ttaaggacat atctggatcg gtaaaatttt ctttgataaa
    36301 atccaatgca tggttcaaaa ttggctgata tttgttcctt gaaggctgtg agggcagagc
    36361 agttaagaaa gaaatgaaca tataaactgt cgaacggtaa agcgagtcgt cggcgctgat
    36421 tgctaagcgt tgactggtgg atgtgcaatg aaccatttct tgcgggattt tcttttcttt
    36481 caggcagaca tgctggagta gcttagtcaa gacaaataaa cgatataatc gtgttcgagt
    36541 tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta gatacttcgt ttttcgataa
    36601 tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc
    36661 ttgaatcaaa tcctcatagc tgataatttg ttctttaagg gaactggcgg tttcaagtat
    36721 catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt ctttctgcga caggaccaat
    36781 ggcgacagaa aaattatttt tttgtccctt ttctaattca tggaccaacg tttgggctac
    36841 ctgataactg gtctcgatca cattttcttc aagagaatca actattaaaa atttgatgaa
    36901 tcgagaggaa acagcagaga agatcacttg ttgattctcc ctaaataaaa acttcaaata
    36961 atcactgaga tgagcgtaat cttcaaagtc tgtactgact tggtttgctg ctaataatac
    37021 ggtcattttt ttccctgcta aagagcgatt gaaagattca gcaagtttca atgtttcact
    37081 gatcgtaagt gagcctttga acaaaccgtt caagaaatga ttttttttca attcgaaaac
    37141 aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct aaagcagtta ctgctttttc
    37201 tattgcttgt ttcaattcgc tacttttaat cggtttaagc agataatcat ctgcctgtac
    37261 ctggattgct cctttcatat aatcgaaatc gtcgaatcca ctaataaata tgagacgagt
    37321 ccaaggaagt agtttccttg cttcttttga aaaagtcaac ccgtccatga aaggcatttg
    37381 gatatcagtc agaatgatgt cgggctgtaa gtcgataatt gaagacagtg ccatctcacc
    37441 atctccagct tcgccgacat aagtgattgg ataataagaa ccaaggacag ttatttgttc
    37501 ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata aaaactttat acatgtttgt
    37561 ttcctccaat tgttttggga gatagaggga tcatcagtgt gacagttgtt ccttctcggt
    37621 atttgctgtc aatcgtgata ggtttttgat catttccgta ataaagaagg agacgcttgt
    37681 ttacgttgta aagtccgtag ccgatactga aatctgaatc gatccctttg gctaactctt
    37741 tacgtatttc tgccagtttt tctgcaggga tgccaatccc gttgtctata actttgaatt
    37801 ggatcatctc atcaattttg catgtggtaa tacgaataaa tcctttgtga cggacgtact
    37861 tcgttccatg gtatacagca ttttcaatca atggctgcaa gatcattttt aaaatagaaa
    37921 caggaaaaag tgtttctggt atatcgatct tatagtcaag catatggccg tatcttattt
    37981 ttaagatgac tagataatca ttgatatggc taatttcttt ttcaagagga atccagtctt
    38041 gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt
    38101 cttcaaagca gtcttgttcg atcaaagaaa taatggcatc caaactgtta taaataaaat
    38161 ggggagtaat ctgagcttgc aatacacgaa cttcactttg tgctaaatgg tattgtttca
    38221 aagcgttctc ccgtaaagac tggtttagat cttccgccat tttattcatg ctagcggtaa
    38281 gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa
    38341 gttgttctga catctcgatc agctgattga tcggttcttg gacctttctc tctaaaaagc
    38401 gacgattctt tttcgcatag aaaaaaatgg tactaagaac tccaagttcc actattgtta
    38461 atagaatgag cgagcggaca agtgtcgtat tttttttgct tgctaagtcg atctccacac
    38521 gaacaaaatc ttgtaagata tctgacagca gttgagtgac agaatctacc tgattgatga
    38581 tctcttcatt ggtatccata aaatcttttg ccaagatatt attgatcagc tcgttttgat
    38641 aatcttccag tgtatcgatc gtacgtagcg atacatctaa cgtactaatt tctttaagtg
    38701 tatttgtatt atttttgctc tctcgaatat cattcctaag ttcttctagg atattttcct
    38761 cattgaactc atctacggtt acttggccag aaatcaagtc ccacatactt tccaaaactt
    38821 tttgatcaac cttcaaagca attgcatctg ctttttggat atttgcgatc gtctgttgat
    38881 aaatcaaaag ctgttgcgaa tataacagta tgctcagtag caaagggata acagcaaata
    38941 gaagcatggc tttgtttgct tgggcaaaaa tctgttttat gcttaaattt tttgtcatga
    39001 tacttctcca gtcaataatt tctggttggg atgttagcta tattctgctg ggaaaagaca
    39061 gtctcggaaa taaaaatatc tttaggtaat gtttttcctg tttgaatatt tccaaaataa
    39121 cgagtaacgg tattggctac ataccagccg acatcaggtt tacactcgac tacacaattg
    39181 acgattcctg agcgtagctt ctcgatcata tcttcttgtc catcaatagt tacaatgatc
    39241 aaatcttctc caggtttgat tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt
    39301 tcatcactat ggctgtataa tacatcgatt tcggataaat catttgtttc taaatatcgt
    39361 ttcatctggt cttttccttt catccgaata aaatcaccga caattcggtg aacaatagtc
    39421 atcggaggtt tatggtcgat ggttccatct ttttttaggg ttggtttacg attgattgat
    39481 tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt tctctgaacc agcaagttct
    39541 aggattctga tttcctgttt ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc
    39601 cgatttcctt ctgctttgaa actggggcca atgtgggtga cgaaaagctc gggatcattc
    39661 gtttgaatat gtctgtcgac aagtatgaca gggatccctg ctcgctttgc ttcttttaat
    39721 acagagtccc acccggattc ttgcaaagga gtaaaaatga tcatatccac tttataggca
    39781 atgaacgtcc gtatatcttg gatttgccgt tcctgattca tgtagccatt tcggtagaga
    39841 acttggtaat cttctttttc aagcgcagtg ataattgatt cagtatgctt tttccgccag
    39901 ctactctccg ttcctgattg cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta
    39961 ttaggtgtac accccatcat ttggtaagcg attacaacaa gggctaaaaa aaataaaaca
    40021 cgtttcactt taaatcactc catctggatt tgttagtact atcttatcag ataaaaggga
    40081 aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga aacttaaaaa aatccaagac
    40141 aaaaaaagta cacctaaaaa atttaaagta aatcccataa aaaaatcaat gttaacgctt
    40201 tctttattag ctatactcgg tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat
    40261 ttagaaagat tgttgggact atcgctattt tgaccgcaag cattctatta agtgcgtgtg
    40321 gcaattcagg atctgcagat gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat
    40381 cagcagaaag atggatcgct gatgggaaca acatggtctc ggaattagaa aaactgggtt
    40441 ataaaacaga tcttcaatat ggagaagata aagtagaaaa tcaagtagca caaatagaaa
    40501 atatgattac aaaaggggta gatacacttg tgattgcttc tatcgatggt tcggctttaa
    40561 ctgatgtgtt agctaaagca aaagaagcag atatcaaggt gatcgcctat gatcgtttac
    40621 tgatgaattc agaaaatgtc gattattacg cgacttttga taattttgga gtaggtgtat
    40681 cgcaagcagc ttatattgaa gagcacttag gattgaaaga aggaaaagga ccattcacga
    40741 ttgaattatt tggtggctcg cctgacgaca acaacgcact aatcaattac aacggagtga
    40801 tgtctgtttt acaaccatat atggacaacg gtcagttggt cgtgccatct ggacagacga
    40861 gtttcagtca aatcgctacg cttcgctggg atggttctac ggcgcaagca aggatggata
    40921 atctgttaag cgcaaattat actgaccaaa cattggatgc tgttttgtcg ccatatgatc
    40981 caataagttt aggaatcatt tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac
    41041 ctttacctgt gattactgga caagatgcga cagttgctgg cgttaaatcg atcattgccg
    41101 gggaacaaac acaaacgatc tttaaagaca cacgtatctt agcaaaaaat acgattgaaa
    41161 tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa tgatactgaa acttatgata
    41221 atggggtgaa aactgtccct acgtatttag caaatacagt atctgtcgat aaagataatt
    41281 atcaagcaga gctgatcgac accgattatt ataaagaatc cgatctgaaa aattaagagg
    41341 aaccaaacaa ggaactaaag agatctaagt cagagagagg ataagaatta tggcggattg
    41401 tattttaaaa atggcagata tcaccaaaaa attttctgga atccgagcgt tagattgcgt
    41461 gaatctgatg attgaacgtg gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa
    41521 atcaacattg atgaatgtct tgagcggctt gtatccatat ggctcctatg acggggaaat
    41581 cttttatgat ggaaagctgt gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat
    41641 cgtcatcatt catcaagaat tagcactaag tccttatctt tcaataaaag agaatatttt
    41701 tctcggaaat gaacaagcag aaagaggcgt gattgattgg gaactgacag aaaagaaaac
    41761 atatgaactg ctgaataaag tcggtttgtc tatcgacccg aatcttctag tatcccagat
    41821 tggcgtaggg caacagcaac tagttgaaat agctaaagca ttatcaaaat ccgtccgtct
    41881 gttgattttg gatgagccta ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag
    41941 attgatccga gagttgaaag agcaaggtgt aacctccatc attatttcac ataagctgaa
    42001 tgaaatcgtg gatatcgcag atcgaatcac cattttacgg gatggacaga cgattgagac
    42061 actagaaaat gaaatgatca gcgaagagca tattattcgc ggaatggtgg gcagagattt
    42121 agttgatcgt tatcctgaaa gaaaaccgga tattggagaa gtttatttta aagtagaaga
    42181 ctggacggtc tatcaccctc ttgatcacga gcgaatcata aacgaccaca tcaacttgca
    42241 tttgaaaaaa ggagagattg taggaatagc tggactgatg ggagcgggca gaactgaatt
    42301 cgctatgagt ctatttggac attcttatgg aagcaagata tccggacgta tattaaagga
    42361 aggggcagag atatcagtta agaccgttcc ttcagccatt gcaaacggac tcgcttatgt
    42421 ctcggaggac cgaaaatctt taggactgaa tctgctgatg gatattcggg aaaacgtgac
    42481 gctgagcagt ttggataaaa taagtcaaaa aggagtatta gataaagaaa aagaagtaac
    42541 tgaggcagaa aatttccgga aaaagatgcg tataaaaaca aactccatcc atcaaattgt
    42601 cagtagtctt agtggtggga atcaacaaaa agtcgtttta tccaagtggc tgatgacaca
    42661 acccgatatt ctttttttgg atgagccaac ccgtgggata gatgttgggg caaaatatga
    42721 gatctacacg attatcgaag aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc
    42781 tgaacttcct gaaatattag ggatgtgtga tcgaatctat acgatgaacg aaggacgtat
    42841 tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa
    42901 agaagaggtg ggttaagttg gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac
    42961 taaatttgaa aagtagagca gctgatcttt ttggtcgcta cagcatggtg atcattttag
    43021 cgggactact tattgcgttt caattgatga cggatggtat tttctggcgt ccattgaata
    43081 taactaacct tgttctgcaa aatagccata tattagtact agctgcaggg atgttattag
    43141 ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa
    43201 ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc
    43261 ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg ggtagcttat gcagggatac
    43321 cggcgtttat cgtgacttta gcaggattgc tgatgtttcg tggactgaca caagttgttc
    43381 taggaggcca atctctagca ccttttccag ctgttttcca aaaaatgtct acgggttatt
    43441 taccagactt aagcgaagga agcagccttc acttcttgac attgatttta ggaatgatca
    43501 tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat
    43561 ttgaagtgga atctccaaca gctttcttgg taaaggcggt atttacagca gtcgttgtac
    43621 taggaataac ttatatcttt gcctcttatc aagggtatcc gattattttg atcattcttg
    43681 gtttgatcgt tgcagcatat gggtttttga caaataaaac agtagcaggt cgacagattt
    43741 atgcgacggg cggaaatcga aaagcggctg aactatcagg gatcaaaaca aagcgaatca
    43801 cgttctgggt attcgtcaac atgggagtca tggcagcttt agctggatta gttttagctg
    43861 ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat ggaactggat gcaatggcgg
    43921 cagtatattt tggtggtgct tcgacttccg gcggcattgg aacaatcatg ggtgcgattg
    43981 tcggtggctt ggtcatgggt gtattgaaca atggcatgtc gattttaggc gtcggggtag
    44041 actggcagca ggcaatcaaa ggattgatct tgcttttagc cgttgtgcta gacttgtata
    44101 ataagaaaaa acgaacaacg taggagaacg ccggttattc agaaaaaaga ctgtgacaag
    44161 acatttgtca cagtcttttt ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac
    44221 taaaaataat atatgttttt ttaccattcg tataaattct ctttttgctc ttgatttttt
    44281 tgcttaattg agttaaatta catagggcgc taaaaaaagc cttgattaaa ttaataatgt
    44341 tcgtgttttg ctggatgtga acatcaggag gataatgtaa tgaaagtatt tgattacgaa
    44401 gatattcaat taattcctaa taaatgtatc gtaaatagcc gttctgaatg tgatacaacg
    44461 gtcacattag gtaaacatac attcaaaatg ccagtagtgc ctgccaacat gcagacgatt
    44521 attgatgaaa caatcgcaga attcttagcg gaaaatggtt atttctatat catgcatcgg
    44581 tttgatgaag cagctcgaat tccgtttatc aaaaaaatga aaaagcgtgg attgattacc
    44641 tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta tagagaagtt ggcagaagaa
    44701 tcgctaaatc ctgattatat cactatcgac atcgcgcatg gacatgctaa ctcagttatt
    44761 gatatgattc agcatattaa aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt
    44821 ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg
    44881 attggtccag gaaaagtatg tattacaaaa atcaagacag gctttgggac tggaggctgg
    44941 caactggcag ctcttagatg gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt
    45001 gggatcagaa cacatggcga tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg
    45061 attggttcat tgtttgccgg tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga
    45121 atcgtgtata aagaatactt tggttctgct tcagaattcc aaaaaggcga aaaacgaaat
    45181 gttgaaggaa agaaaatctg gatccaacac aaaggatctt tgaaagatac actagtggaa
    45241 atgcaacaag accttcaatc atctatttct tatgctggag gaagagatct ggaagccatt
    45301 cgaaaagttg actatgtcat cgtgaaaaat tcgattttta atggagacac aatctaaaaa
    45361 ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc
    45421 aaacaaaaat agttctttat atgttttgtt tggctggaat tattatcgca gatacaagct
    45481 tttgaacatc attattcaga ataagggact gtgataagat ttttgtcaca gtcccttatg
    45541 ttttgcaaaa aaagtttttc ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag
    45601 acaatagaaa agagaagctt atgtgggaaa aagtagagaa aaaacaagga ccgatttatc
    45661 gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc
    45721 aacttgaatc agaacgaaaa ctagggcaac tttttggtgt gaatcgttcc accgttgtcc
    45781 atgcattgga agagcttagg gagcttgggg tactaacgag caaacgtggc agcggatggt
    45841 ttgttaatca gactgaatgg gggaaattcg ctgttccaag aatcgattgg cggcaaatga
    45901 tctctcctcg ttatgagcag acggactggt atgagcaaaa aataagagaa gcaaagcaga
    45961 tccaaaaaac atcgtttctt gatttatacg ctagcgagat gccagatgag cttttgccga
    46021 attttgagtt tccttcttat tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc
    46081 ttttaggcta tactccgtta cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat
    46141 tggcattttc ccccaaccag cttcttgtga ctggtggcgg tcagcaagca atctttttga
    46201 ttttacaaac gattctttca gctggagagg ggatagctgt agagtcacct tctttttttt
    46261 accgattacc tcttttcaaa gcttcaggaa cgcgtttatt tgggataccg atggatgaag
    46321 aagggatcga cttagaaaaa ctgaaagaat cgatccataa aaataaattg aaagcagtgc
    46381 ttatcaaccc gaattttcaa aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa
    46441 agctagtaga attgtgtcga cagtatcggc ttccaattat tgaagacgat gtatttacgg
    46501 atctttcatt tctaaaccaa gaagaagtcc ttcctatacg aacgattgat ccggataatg
    46561 tgttatacgt cggttcgtta tctagggttt taggaaaaac aacgaaaatc ggttgggtga
    46621 taggacctga gacttttatc tcgcaactag ctcaagcgca agaaatgatg gagttttcga
    46681 tgaatatcct tacacaaatc acagtggcta atgtatttaa tgaagcaatt gatttgaaaa
    46741 tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact gataagcgct tggggagatt
    46801 cacaatcgtt tttcaagctt cattcaattt taggtggtta ctatgcctgg attacttggg
    46861 atgggaaaaa actagacccc gaactagcag aaaaagtagt agatatgggt cttggaattg
    46921 caccaagtct actttttggg caagatataa atggaatcag aatcaattac agtaggctgg
    46981 atgaaaacca aataccgttg ttttattcaa agatgaaaat tctagaaaag tggttaacag
    47041 aataatttca caaagtaaat agattaaaga atataacagc ttggatttaa atttcaagct
    47101 gtttcttttt tttcggaaaa agaatacgat ataaagaaac taagaaaaaa ccattatttg
    47161 tacgtccgtt cacgatgtgt aaataaaata aatgtttgca acaaaactgt ataacaccaa
    47221 cgtttttaaa tagaaacaga tggttgtaag tttgattaga aaatagaaaa aatgcagatg
    47281 aaatataaaa cgctttcctt attgtgattt tattcactaa tgctgttaat atgcggattg
    47341 gcataatttc ctttcatcgt gaaaatttgt gcttttagct tgtatttctc ataaatccat
    47401 gataatttat taatgaagac ggttaaatag tgatacagtt ttattcactg tttcaatcgc
    47461 agaatgaaga gattttctta tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa
    47521 gcaccgatcg acttccaagc actgctagat gaagtcaatg cagatttccc agtatatcaa
    47581 gcacttgatc aagatggaaa cgtagttaac aaagatttag tacctgattt atccgatgat
    47641 gaactcgttg aattaatgac tcatatggta tggtctcgtg tattagacca acgttcaaca
    47701 gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa ctgctggaca agaggcaagt
    47761 cagctggcta gtgcttacgc atttgataaa gaagatgttc ttcttccagg ttatcgggat
    47821 gtacctcaac tagtaaaaca tggtttacct ttatctcaag cttttttatg gtctcgagga
    47881 catgctgcag gtaattctta tccggaagaa ttgaaagctc taccaccaca aattatcatc
    47941 ggtgcacaat atgtacaagc agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa
    48001 aatgtcgtct tcacttatac tggtgatggc ggttcatcac aaggtgattt ttacgaagca
    48061 atcaatttcg ctggcgctta ccatgcaaat gccgtatttt atatccaaaa caacgggtat
    48121 gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc
    48181 gcagctggga ttcctggtat tcaagtcgat ggaatggatc cgcttgcagt atatactgta
    48241 tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac cagtcctaat cgaaacactg
    48301 acttatcgtt atggaccaca tacactatct ggtgacgatc caacccgcta ccgtacaaaa
    48361 gacacagatg acgattggca gaaaaaagat ccattgatcc gcttccgtaa atatttgacg
    48421 gaaaaaggac tttggtctga agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa
    48481 atcaaagcag ctattgctga agccgacaaa gtaccaaaac aaaaggtttc agatttcttg
    48541 aaaaacatgt tcgaagtatc tccacaatca atcaaagaac aaattgcaat ttatgaagcg
    48601 aaggagtcga aataatcatg gcacaaaaaa caatgatcca agcaatcaca gatgccttag
    48661 cacttgaact agaaaatgac gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg
    48721 gaggagtttt ccgggcaact gaaggattgc aggaaaagtt cggagaagac cgagtattcg
    48781 atactccttt agctgaatct ggaatcgcag gattgagttt cggtcttgcg ttagaaggat
    48841 ttcgtccagt tcctgaaatc caattctttg gttttatttt cgaagcaatg gacgaagtag
    48901 tagctcaaat ggctcgtaca agatatcgaa tgagcggcac tagaaatcta cccatcacaa
    48961 ttcgttcgcc atttggtggc ggtgttcata caccagaatt gcattcggat aatttagaag
    49021 gtttgatcgc tcagtctcct ggtattcgag tagtgattcc ttccaaccct tatgatgcaa
    49081 aaggactatt gatttcttct attagaagta acgatccggt tgttttccta gaacacatga
    49141 aactatatcg ctcattccga gaagaagtgc cggatgaagc ttacgaagtt cctttggata
    49201 aagcagcagt tactcgtgag ggaacagatg tatctattat cacatacgga gcaatggtgc
    49261 gtgaagcaat caaagcagca gacaatcttg caaaagaaaa tatatctgtt gaaatcattg
    49321 atcttcgtac agttgcgcca ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg
    49381 gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg cgttgccgcg caagtagttt
    49441 ctgagatctc agaacgcgct atcctttcat tagaagcccc aatcggacga gtttctgcac
    49501 ctgatacagt cttcccattt ggacaagcag aaaatgtctg gttgccaaat gcaaaagata
    49561 tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa gaagggacga aacaaagtca
    49621 tggcttatca atttaaattg ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    49681 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    49741 atgacaaatc agtagaagaa atcccgtcac ctgttacagg aacggttaaa aatgtgattg
    49801 ttccagaagg taccgtagca aatgttgggg atgtattagt agaaatcgat gcaccaggac
    49861 acgaagacaa tgaaggggac agtggtgtag ccgcagaatc ccaaactcca gctaaaccgg
    49921 ctgctgaacc cactgttgat acagaatcag ctggatcgtc aagcgaagga gtcttccaat
    49981 ttaagttacc ggatatcggt gaaggaatcg cagaaggtga aatcgtcaaa tggttcgtca
    50041 aaccaggaga tacgatcaat gaagatgata cattactaga agttcaaaat gacaaatcag
    50101 tagaagaaat tccgtcacct gtcacagtga cagttaaaaa cgtgattgtt ccagaaggca
    50161 ctgtagcaaa tgttggggat gtattagtag aaatcgatgc tcctggacac aatagtgcac
    50221 cgtcaactag tgcgccatca gctgaagcac caaaagaaaa agtggaaaca tcaggttcag
    50281 caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt ggctatgcca tctgttcgtc
    50341 aatttgcccg tgaaaaagat gtagatatct cacaagtaac tgcaactgga aaaggtggca
    50401 gagtaacaaa agaggacatc gaaaacttct tggcaggtgg tccaagcagt gcaccagcga
    50461 aatcagaagc gccagaagcg gcagcaccga aagaagcagc tcctgcagca gaaagcaaac
    50521 cagctgcacc agcaaaacca ttcaagtcca acttaggaga cttggaagaa cgtgtagcaa
    50581 tgacgccaac acgtaaagct atcgctaaag caatggtcaa cagtaagcat acagctccac
    50641 acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg ggataatcgg aaacgattta
    50701 aagaagttgc tgctgcaaat ggtacgaaac ttactttctt gccatatgtc gtgaaagctt
    50761 taacagcgac tgttaagaaa tacccagtat tgaatgcatc tatcgacgat gcaaaccaag
    50821 aaatcgttta taaacattac tacaatatcg gtattgcaac tgatacggat cacggactat
    50881 atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt tgctattgca gacgaaatca
    50941 atgagaaagc aaaattagct catgacggca aactatctgc agaagatatg cgcaatggaa
    51001 caattacgat cagcaatatc ggatctgtag gtggcggttg gtttacacca gtcatcaact
    51061 atccagaagt agctatttta ggtgtaggaa cgattgcaca acaaccaatc gtaaatgctg
    51121 aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt aagtttcgat caccgtatcg
    51181 tagatggagc aactgcgcaa caagcaatga ataatatcaa acgtctttta gctgatccag
    51241 agctattaat gatggaagga tgataaacaa atggtagttg gagattttgc tgtagaatta
    51301 gatacagttg taattggtgc gggacctggt ggctatgtag ctgccatccg cgctgctgaa
    51361 atgggacaaa aagtagcaat cattgaaaga gagtatattg gcggtgtttg tttgaatgtc
    51421 ggctgtattc cttcaaaagc actgatagct gcaggacacc attatcaaga gtcactagat
    51481 tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag attttgcaaa aacacaagaa
    51541 tggaaagaaa acaaagttgt ccatacgttg acttctggtg ttggtttcct attaaaaaaa
    51601 cataaggttg aaacaatcga aggagaagcg ttcttcgtag atgatcacac actacgcgtc
    51661 attcatccag attcagctca aacttattcg ttcaataacg caatcatcgc aacaggttcc
    51721 cgtccaatcg agattccagg atttaaattc ggaggacgtg tgttagattc tactggcgga
    51781 ttagcattga aagaagtacc taagaaattt gtgatcatcg gtggcggtgt gattggtgcc
    51841 gaattgggcg gagcgtacgc aaacttagga gcagaagtaa cgattcttga aggctcacca
    51901 caaattttac caacttacga aaaagatcta gtaaaattag tagaagatga tttcaagaaa
    51961 aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag cagtcgataa cggtgacagc
    52021 gtgacagtga aatatgcagt ggacgggaaa gaagaatccg ttactgctga ttatgtgatg
    52081 gtcactgtag gtcgtcgtcc gaatacagat gatatgggct tagaacaagc gggtgtcgaa
    52141 gtaggagaac gaggattgat cacggtggat aaacaaggac gtacgaacgt acctaacatc
    52201 tatgccatcg gtgatatcgt tccaggggcg gcattagcac acaaagccag ttatgaagca
    52261 aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg tagattataa agcaatgccg
    52321 gcagtagcct tcactgatcc tgaattggct tctgtaggta tgacgatcaa agaagcaaaa
    52381 gatgctggta tcgaagcaaa agcatataaa ttcccatttt cagggaacgg tcgggcatta
    52441 tcgcttggta aaacagaagg attcatccgt ctagttacga cgatcgaaga taacgtgctt
    52501 attggcgcgc aaatcggtgg agtcggcgca agtgatatgg tctctgaatt agctttagca
    52561 atcgaatcag gaatgaatgc tgaagatatc gccttgacga ttcatcctca tccatctctt
    52621 ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt taccaatcca tatttgattt
    52681 gaataataca ggcgaaacgc aactgaaaaa tcagttgcgt tttgtttttt agaattatca
    52741 ataatattat tatgtaaact taaaaatatg acaacttctt ggtttattac cacttcctat
    52801 gctacactga agaggaatat gaaataggag agttgaagat gcaagaatat cagtatccac
    52861 ttgatttaga ttggacaaca gacgaaatgg tcattgtaat gaagatgtgg gaagatctgg
    52921 aacgtgcgaa tgaaaaaggg ataaacaatg aagctttttt gaagacttat cagcagttta
    52981 aaactgttgt caaatccatt ggtgaggaaa aacgattggg acgggaattt gaaaaagctt
    53041 ccggttattc tttatatcgt acagtgcagc aagcaaaaaa aaatccaaac aaaactttga
    53101 gaatgaacgg gtgagataaa tggaacagat gattgatcat atcaagtcct ggcttgaaga
    53161 agctggtgag aaaatcaaat cttctcaaca aacattaaca atctcgcaaa aatcaaatcg
    53221 aacggatcta gtaacaaatg tcgatcgaaa catccagaat tttctaatcg aaaaaatcca
    53281 ttcctttgat ccagaggcga aaatattggc agaagaagaa gggtgtaatc aattatcgga
    53341 tctcgatgga agagtcttta tcatcgatcc tattgatggc accttgaatt ttgtgattga
    53401 aggggaaaat ttttgtatta tgctcgctgt ttatgaatcc ggcgttggaa agcttggttt
    53461 catttatgac gtgatgagaa atgaactttt ttggggtgga aaaggaatag gcgtgtataa
    53521 aaatgatgag ccattgccta gaccagcaaa taaatcctta tcggaaggct tacttggtgt
    53581 gaatagttat cttttcggtc ataataaata tggaatccga gaaattgcgg aaagcagcat
    53641 ggggacacgt atgtacggat gcgctggtct tgaactagtg gcaatcttga aaggaaacca
    53701 cattgcttat atttcaaacc ttagcccttg ggattatgca gcgggaaatg tcttattgga
    53761 agagtttggt atggtaacaa gcggtctttt tggtactcct ttgacatttg aaaaaaggga
    53821 atactattta gcagggactt cttgtgcata tgcagaaatc gcagaccttt tgaaaaaaga
    53881 aggctgaaaa aaaggtagaa atcattcaca aaaatgataa aaacgagcaa aagattaatt
    53941 ttctcgaaaa aatgaaaaca ttttactata tttcatgaaa aaagtctgct ataattagca
    54001 gtcgagtaaa atttgccctg tcataaagaa ccaataaaaa aggagttagt tacattgaat
    54061 tatagaaacg atatccgtaa cgtcgcaatt attgcccacg ttgaccacgg aaaaacaaca
    54121 ttagttgatg aactattaaa acaatcagat acattagacg cacatacgca attgcaagaa
    54181 cgtgcgatgg actcaaatgc gctagaaaaa gaacgtggta tcacgatttt agccaaaaac
    54241 acagctgtag actataaagg tattcgcgta aacatcatgg atactccagg acacgcggac
    54301 ttcggtggcg aagtagaacg gatcatgaaa atggttgacg gcgttgtgtt ggtcgtagat
    54361 gcgtatgaag gaacaatgcc tcaaacacgt tttgtattga aaaaagcact ggaacaacat
    54421 atcacaccaa tcgttgtcgt aaacaagatt gacaaacctt ctgctcgtcc tgagcatgtc
    54481 gtagatgaag ttcttgaact attcatcgaa ttaggagcag atgatgatca gttagacttt
    54541 cctgtgattt atgcatctgc actaaatggt acgtcaagct tgtcagatga tccagcagat
    54601 caagaaccaa ccatggcacc tatttttgat acaattattg aaaaaatccc tgctcctgtc
    54661 gataacagcg acgaaccatt acaattccaa gtttcattac ttgactacaa cgattatgta
    54721 ggtcgtatcg gaatcggacg tgtatttaga ggaacaatca aagtaggaga ccaagtagca
    54781 ttaattaaat tagacggaac agttaagaaa ttccgtgtaa cgaaattatt tggtttcttt
    54841 ggactaaaac gtctagagat tcaagaagca aaagctggag acttgattgc tgtctcaggt
    54901 atggaagata tctttgtcgg tgaaacagtt actcctgtgg atcatcaaga tgcgttacct
    54961 atccttcaca ttgacgaacc aacattgcaa atgactttct tagttaataa ttcaccattt
    55021 gccggtcgag aaggtaaatt cgtaaccgct cgtaagattg aagaacgttt gatggcagaa
    55081 cttcaaacag atgtatcctt acgagttgaa ccaacaaact ctccagatgc atggacagtt
    55141 tctggtcgtg gagaattgca tttgtctatc ttgattgaaa acatgcgccg tgagggatac
    55201 gaattgcaag tatctcgtcc agaagttatt gaaaaagaaa tcgacggtgt aaaatgcgaa
    55261 ccgtttgaac gcgtgcaaat cgatacacca gaagaatata tgggtagtgt tatcgagtcc
    55321 ttgagcttac gtaaaggtga aatgcaagat atggtccata caggaaacgg acaaatccgt
    55381 ttgacattct taacacctgc ccgcggtttg attggttatt caactgaatt cctttcaatg
    55441 acacgtggtt acggaatcat gaaccatact tttgaccaat atctgccaat gcttcctggt
    55501 caaattggcg gacgtcacca aggggcgctt gtttcgatcg atacaggaaa agcaacgact
    55561 tattctatca tgagtatcga agaacgcggt acagtcttcg tagaaccagg tacagaagta
    55621 tatgaaggaa tgattatcgg ggaaaacagc cgtgataatg atttgactgt caacatcacg
    55681 aaagcaaaac aaatgacaaa cgtacggtct gctactaaag accaaacatc tgtcatcaaa
    55741 aaaccaaaac aattgacgtt ggaagaatct ttggaattct tgaatgatga tgaatattgc
    55801 gaagtaacac cagaaagcat tcgcttgaga aaacaaattt tagagaaaaa tgctcgtgaa
    55861 aaagcatcta aaaagaaaaa ataatctgta aaaggatgaa gagagaaacc agcttgttat
    55921 aaaaaatagc tggtttcttt ttttgtccaa ctcttttctg tggagaagtc atctttgtca
    55981 atggacataa attcagaaaa tacgccgaaa gacgtttaaa agacttttaa aaaacttatt
    56041 tctagagagt ttttgtttca taataagata atgtttcacg aaaggagatc aacttgtcct
    56101 tcgaagaaaa tcgaagtaaa atggcaagag aaaggagcgg gaagatgaac gacttattaa
    56161 aacaatactt tggctatgat gagtttagac ctggtcaaaa agaaattatc cagaaagtca
    56221 ttgatcagga aaatgtatta ggaatcatgc ctaccggaag tgggaaatca atctgttacc
    56281 agcttccagc tttactatta gatgggctta ctgtggttgt gtccccttta atctctttga
    56341 tgaaggatca ggtggacgcg gcgaatcaat taggtatacc cgccactttt atcaatagct
    56401 cgttagatgg ttacgaaaca gctagacgct tccaagaaat cgatagacag cagtaccgtt
    56461 tactttatat cgctcctgaa cgttttatca tgccggattt tatccaagca atgaagcgat
    56521 ggaacgtccg tatgatcgct attgacgagg cacattgtat ctctcagtgg gggcatgatt
    56581 tccgcccaag ttatttacag atggcgaacc agctagatca actgccaaat cgtcctgtaa
    56641 ttgttgcttt gacagctaca gcgactgtgc aagtagctgc tgacataaaa agacttttaa
    56701 aaattccaga aaacaaccat attcagactg gttttgaacg agaaaatcta cgatttcaag
    56761 taattaaaga tcaaaaaaaa gaacaatatc taatcgaata tttaaagatc aacaaaaatc
    56821 aatctggtat catttatgca gcaacgagaa aagaagtaga ccgtctctat catttgctta
    56881 gaaaattcga tttttccgtg ggtagatatc atggtggtct aaatgagaat gagcgaacag
    56941 aaatgcaaga agccttttta tacgatcgct tgcagctgat tgtagcgaca aatgcatttg
    57001 gtatgggtat aaataaaagc aatgtccgtt ttgttatcca ttatcaaatt cctggctctc
    57061 tagaagcata ctatcaggaa gctggtcggg cgggaagaga tggtctttcc agtgaagcca
    57121 tcctgctttt ctctcctcaa gatatccaag tccaaaagtt ttttatccag cagtcccaaa
    57181 gagaagaagg gcaaaagcaa aaagaatatg aaaaattaaa agcgatgaca gaatacgtgt
    57241 atattgagtc ctgtcttcag caatacatcc taaactattt tggcgagaca agcagtccgt
    57301 gcaaccgttg tggtaactgt ttagatgaca gagaaatagt agaagtaacg acagaagcac
    57361 agatggttct ttcttgctta aaacgtatgg gtgagaacta tggtaaacaa atgctgatga
    57421 aagtcttagc aggatcgaaa gaacaaaagc tgcaagcttt aggttttgga catttatcta
    57481 cctatggact gatgaaaaac caatcgcaaa aagaaacgat gcagttaatt gaatatttga
    57541 tatcgaatgg ctatcttctg accatcaatg gtgagtatcc tgttttgaaa gtaacagaaa
    57601 gagggataca agtattgaaa ggacaagaat ctgtttatcg aaaggaaccc aagaaagtcc
    57661 agcagctatc ggatgaagaa accgatacac tatttgaagt gctgcgggaa ctgcgaacgg
    57721 atctagcatc agaagcaggc gttcccccgt atgtcgtatt ttcagattcc acattgaaag
    57781 aaatgagccg aatacgtcca tcaagcagat tggagatgct tcagataaaa ggagttggcc
    57841 aaagcaagct tgataaatat ggcgaagcct ttttatctcg gataaaaaat gcggactcta
    57901 acgttctgga taagtagaaa gaacgaatac gtaaaaatga ataaaaacaa ctggttaaat
    57961 ctgttttttt tgctccttat gaaaatcaaa tatgttataa ttaaggaatt agaatgggag
    58021 gtaagcacag atggattctt tgtcgaaaaa acttgcgatc caagtattaa atgatgaagc
    58081 agaacggatc aaacgattaa tccgaaatca aaacaacagt ctctgtatct cacaatgcaa
    58141 agccttcgaa gaagtggtag atacacagat gtacggcttt tcccggcaag tcggttttgc
    58201 tgtccgtata ggagtaatcg gaaagaacga gggccagctg atgttaagtg agctagaacg
    58261 agaattgaat cagttatata gtgaggttta ccaagaaatt tatgataaaa aagaagttgg
    58321 caaggaggaa tagacttgcc taagaaagtg aaaaaaaggc atctattaga ctatagcatc
    58381 ttgattccct atttaatttt atgtgtattg ggattgatca tggtatatag ttctacgtcg
    58441 tatctattat tagaaaacgg acaaaatccg tccgcatcag tcattaacca gagtattttt
    58501 tgggtgctta gcttgattgc tatcgcacta ctttataaaa tgaaaacaga tgttttgaaa
    58561 aaccagcgtt tgatcatggc agccatcgca gttttgacga ttttgctgct gattgttgtg
    58621 ttttttggta aggagatcaa tggggcgaaa ggttggctgc aaattgcagg attctcgatc
    58681 caacctgccg aatacctaaa aatcatttct atctggtacc tgtctctgac tttatctaaa
    58741 agacaaaaca gtgtacaaaa agattttctt gggactgtga aacgtccact tgcaatggtt
    58801 atcggactta ctgcattagt cgctattctt cccgattttg gtaatgcggc agttatcttt
    58861 ttgattattt tggttctgct tttagccagc ggagtcaatt atgtgtatac tttgattgta
    58921 ggagtaggag gcttttgtct aagtactttt acgatctggc tgatcaatat cacaaacgga
    58981 aagatcttac ccggacgttt acagtatatc tataatcgat ttgctattta ccaaaatcct
    59041 ttctcagacg aattaaataa agggcatcaa ctagtcaacg gctactatgc catgttcaac
    59101 ggaggactat ttggcagggg attaggtaac agtatccaga aaaaaggatt tttacaagaa
    59161 gcacaaaccg attttattta tgcaatcgta gtggaagaac tgggagtgat tatggggatt
    59221 ttgatattag cgttgctatt ctttatgatt gtgcgcattg tccttgtagg tatccgttca
    59281 aaagatccgt tcaattcgct tttgtgcatt gggatcggcg caatgttttt gatccaagta
    59341 tttgtcaatc ttggagggat tactggcgtt attcctttga cagggatcac gttcccattt
    59401 ttaagtcaag gaggctccag tttgctgatg ctttcgattt gtgtcggctt tgtcctcaac
    59461 atcagtgcgg atgaaaaacg caagagctta ggtttataat aaaaaaagat gtaggagtgg
    59521 ttcgatgaaa aaagttttag ttgctaacag gggtgaaatc gctgtacgtg tatttcgtgc
    59581 ttgtacagaa ttaggaatta aaactgttgg aatctatgca gaagaagatg aatattccgt
    59641 acaccgtttc aaagcggatg aagcatattt agtaggacaa ggaaaaaaac cgattgatgc
    59701 gtatctagat attgaaggga tcatttctat cgcgaaagaa tgcggagctg acgctattca
    59761 tccgggttac ggtcttttgt cggaaaactt gaattttgcg caacggtgcg aagaagaagg
    59821 catcattttt gttggaccca aactgcatca tttagatatt tttggagata aaatcaaagc
    59881 aaaagctgca gctatcgaag cggggattgc ttcgattcca ggcacagatg gaccaatcgc
    59941 ttctatagac gatgccttgg agtttgcgaa acaatacggt tatccgatta tgatcaaggc
    60001 agctctaggc ggcggcggac gcggcatgcg tgtagctcac gatgaaaaga gtgcaagaga
    60061 gggctacgaa cgtgcgaaaa gcgaagcaaa agcagccttt ggtagtgatg aagtgtatgt
    60121 tgaaaaatac atcgctaatc ctaagcatat cgaagtacag attctcgggg atacgcatgg
    60181 aaacgtcatc catctttttg aaagagattg ttctgttcag cgccgtcacc aaaaagtagt
    60241 agaagtagcg ccttgtgtct ctatgaatga acagcaacgt caaaaaatct gccaggcagc
    60301 tgtccaattg atgaaatatg tcgggtatgt caacgcaggt acagtagaat ttcttgttga
    60361 aggagatgat ttttacttta tcgaagtcaa ccctcgcgtc caagtggaac atacgatcac
    60421 agaaatgatt acagatattg atatcgtaac aacgcaactg ttgattgctc aaggtttgga
    60481 tctgcataaa gaaatcggat tgcctcagca agaaggaatt aaattaaatg gttcagccat
    60541 tcaatgccga atcactacag aagacccgtt gaataacttt ttaccagaca cagggaaaat
    60601 cgatacgtat cgttcacctg gtggttttgg cgtacgtctg gatgtcggaa atgcttacgc
    60661 gggctatgta gtgacaccgt attttgattc attgctagta aaagtatgta cgcatggtgc
    60721 tacctttgaa acagccattc agaaaatgga acgttgcttg aaagaattta gaatccgtgg
    60781 agtgaaaaca aacattccat ttatgctcaa tgtcatcaca catcctgaat tccaatcagg
    60841 aaatgcaaaa acaaccttca ttgatagtac agcaacatta tttgaatttc ctcgactacg
    60901 agaccgcgga aacaaaacga tgaaatatat cggtgaaatt actgtgaatg gttttccagg
    60961 tatcgaaagt ggcgaaaaac cattttatga agaaccacgt atgcctaaag atctaatcac
    61021 aagaactgat tacgtaacgg ctaagaatgt attagatgcg aagggtgccg atgctttggt
    61081 cgaatggatc aaaggacagg aaaatttgtt gttgacggat acgacattta gagacgccca
    61141 tcaaagtctg ctagcaactc gtgttcggac aaaggatttc aagcagattg cacgtttgac
    61201 tggagaaggt cttcctgaac tcttttcaag tgagatgtgg gggggagcaa catttgatgt
    61261 ggcttaccgc tttttgaatg aagatccttg gcaacggttg agaaaaattc gttctttaat
    61321 gcctaatacg ttgctgcaaa tgcttttcag aggttcaaat gccgttgggt attctaatta
    61381 tcctgacaat gtattggtgg aatttgtcaa agaagcagca gcgcaaggaa tcgatgtatt
    61441 tcgaatcttt gatagtttga actggactcc acaaatggaa aaaagtatcc aagctgtacg
    61501 ggatactggt aaaatcgcag aggcagctat ttgctatact ggcgatatca acgatccaag
    61561 tcgggcaaaa tacaatgttc agtattataa agacatggca aaggaactag aacaactggg
    61621 tgcgcatatc attgcaatca aagatatggc tgggctgctt aaaccgcagg cagcttatcg
    61681 tttgattagt gaattgaaag aaacgacaga tctgccaatc catctgcata ctcatgatac
    61741 cagcgggaat ggaatcatca cttattctgc tgcttcaaaa gcaggagtag acatcgttga
    61801 cgtggcaatg agtgcaatga gtgggaatac tagtcagcct agcatgagca gcttgtatta
    61861 tgcactggtc aatggtccac ggctgccaga aatcacgatt gaaaatgcac agaaattaaa
    61921 ccattattgg gaagatgtgc gcatgtatta caaaccgttt gaaaacggct tgaatgctcc
    61981 tgaaacagaa gtatatatgc atgaaatgcc aggaggacag tattcgaatc tacagcaaca
    62041 ggcaaaagct gtcggattag gtcatcgctg ggatgaaatc aaacaaatgt atcatactgt
    62101 caacttgatg tttggcgata tcgttaaagt aactccatca tctaaagtag ttggagatat
    62161 ggcactattt atggtccaaa atgatcttac agaagaagat atttatgaaa aaggcgaaac
    62221 actaagtttc cctgaatctg ttgtgacttt cttccaagga gaactagggc aacccgttgg
    62281 cggatttcct aaaaaattgc aaaagattat tcttaaaggc agacctgcat tgaatgaacg
    62341 tccaggtctt ttggctgaat cagtcgactt caacgaagta aaaaaagaat tggcagaaaa
    62401 aattggctat gaaccaaaac aagacgaagt attaagctat ttgatgtatc cgcaagtctt
    62461 tttggactat caaaaagcat ataatcaatt tggcgatgtt acattactgg acacaccaac
    62521 atttttccaa ggtatacgtt tgggtgaaac aatcaatgta caaatcgaac gcggaaaaac
    62581 gcttatcatt cgtttagatg aaatcggaga acccgatatc gaagggaatc gcgtactgtt
    62641 cttcaatttg aatggacaaa gacgtgaaat cactatcaaa gataattcga tcatcagtac
    62701 ggtccaaacc cgattgaaag ctgaaccgac aaaccgagaa caaattggag caacgatgtc
    62761 tggttctgtt ttggatgtat tagtgaaaaa aggcgataac gttaaaaaag gtgatacgtt
    62821 gatgattact gaagcgatga aaatggaaac ggccatcgaa gcacgttttg acggagaagt
    62881 cgcacatgta tatgtgtctt caggagacac tatttcgtct ggtgaccttt tgattgaagt
    62941 gactgagaaa taataagcga aaggtgggga aacatgaaaa gactgggttt gttttggctg
    63001 attctgctat tagttattgt ggcattctac atggaaccag tcttgtttcc gccaaaactt
    63061 gaagtgaagg aaaactctga tcaacaaata tcaaaccaaa tgacaacgtg gaaataccag
    63121 gagcttaaag caactggttt ttctacttat atcggaaaac cgatcgatca gctggaaaag
    63181 gattttggcc aagcctatga tcgattaact agcggatttg gttttgaaac aagatattat
    63241 gaaaataaag ctagtcatct cacatttgaa gcgaacatcc aagacagcag agtcacaact
    63301 gttaaagtac tgcaaacagg gcctgctgat atcgcgccgt tttatttagg gatgacgatg
    63361 caagatctta cgaaaatcac tactatctat actaatttca cttttgagta ccatgataca
    63421 gaagttggaa tcgaactaat ggaagaggat atgaattatc gtccgctaat tgcttttgat
    63481 aacgacactt ttgctatttt attttttgat caaacaacaa acggcctatt ttcagttgtg
    63541 tatttagata aagatagtct tttgaaacta ttgccatatc aagtgtttgg tgaaggcctt
    63601 ccacattatc aagcagataa atcggctgat tgggaatcaa tcaatcgcgt taaagaacga
    63661 aaaagtacga ctttattaaa tatgcttaga agagaagacg aacttcccat atacaatcaa
    63721 acacttgcct ttcaaaacca cagtcagctg ctactacatg attttttgac aaggcctgag
    63781 gaaatattgt cagaggaacg tatggctgat tggcaaaaat cgctaggcag tgctcaaacg
    63841 acagtgaaat tctcactgac gaatgatgaa ttggagaagt taatcagtaa acaaaaatta
    63901 gaaaatacta gtgggctatt tattcatccg gcgattgacg ctactttttc gtttttatat
    63961 tggtacagcg atccttacaa ccatgaccgt ttcatggacc cgggaacgga ttctgtaggc
    64021 attgcttttt ctaaagaaaa tatgttagtc ttattgcaag aagaaaacgg agaaagtagt
    64081 gatagcagtg atcgttaacg aagagctgtt tcaactggag gatcaatgcc tccaagtcgc
    64141 tgaaatgata aaaaagagta aaacgatggc ttcttatctt gaacataaac agtcaatgga
    64201 agaatctgca aaagtttgcc agttgaaaga agcgttcttg tctaagaaag aagcatttga
    64261 aaatgtagcg gcatatggtg agtatgcacc tgattatcgt gaaaaaaaac gagctgttcg
    64321 aaaagcaaaa agacagcttg atatggatga gcatgttgca gctttccgat atagtgaaac
    64381 acagctgcaa agtctgttgg atcaaattgt ccaagtactt gccgaagaag tttctaatga
    64441 aatcaaagta gatgcaggta gcccgttttt tgaaacgaaa aaacactttg gatgcggagg
    64501 taattgtcat gcaattagac aatagtgaat ttgaaataac aaaacgacgc gggctgatcg
    64561 tatgggtcta cagcttaaaa caattaaaga atctgaaaaa gttcggcttg ttgcattatg
    64621 tctcaagaag aatgaaatat gtcgtgcttt acttaaatga agagacattg gaagaaacag
    64681 aagaacgaat ccgtaaatta cattttgttc gaaacgtaga acgttcttac cgaccggata
    64741 tcgaaatgaa ttttgccgaa aaaataggaa acaaaacagt attaaaagac gaaggtttcg
    64801 aaattgaaga gctaaataca gaaatccgat tagctgaaca tctttaaaaa tctcttatga
    64861 gcagttttta aataaaaaat aacttggata acgatcgatt tttgatcatt gtccaagtat
    64921 ttttttggta tactagtacc agtaccattt ctaaggagtg agtagatgcg gataatatca
    64981 ggaaattatg gcgggcgccg tttaaaaagt ttagcagggg cgaacaccag accaactaca
    65041 gataaagtaa aagaatccat attcaatatg attggaccat attttgatgg agagacagta
    65101 ttggatctgt ttgcaggaag cggtggttta gctatcgaag cagtatctag aggctgcagt
    65161 catgcggtat gcgtagacaa aaattaccaa gcgctaaaaa tcatcaaaga aaacatcgaa
    65221 attacgaaag aaccagagaa atttaccaca ataaaacttg atgcggacaa agcaatcgaa
    65281 cggctagcag cggagaaaca acaattcgac tacttgtttc ttgatccgcc atatgcaaaa
    65341 caaaaaataa tcgatcaaat ccataaaatg gaagaactgg gacttttttc taaaaccgca
    65401 gttatcgtat gcgaaacgga taaaacagtc gaattgccag aaactgtggc tggattccat
    65461 caaataagaa aacagattta tggcataacg gccgtaacta tctatagaaa agagggaaat
    65521 caatgaaacg tgcattattc ccaggaagtt ttgatccttt tacaaaaggt cacttagata
    65581 cggtggaacg tgcggctaaa ttattcgatg aggtagtaat tggtgttttt atcaatactt
    65641 caaagaaaag tttgtttccc ccagaagaaa gaatgacatt gatcacaaaa gctgtttctc
    65701 atcttcctaa tgtaaaagtc atgcatcaag aaaatcaatt gacggtagaa acagcaaaag
    65761 agattggtgc agatgcgttg atcagaggca tacgaagtat caaagacttt gaatatgaac
    65821 gagagattgc tcagatgaat catcatctat atgatgaatt ggaaactgtc ttcttattag
    65881 caaaaccaga atatagtcac gtgagttcca gtattttaaa agaagtactg cactttggcg
    65941 gagatgtgag cagctactta ccgccagtga tcaacgaagc tttagctgga aagcgtgaat
    66001 caaatgaaag ctaaacaatg gttgaaaaca gtactgatta tcatatttgg aatgttgatc
    66061 attggatttg tagtagttcc cttgccgtat tatgtagaat caccgggagc cacgatcgat
    66121 ctgaaagaac taattacggt caatgataag gaagataaag gttctgggtc tttctctctt
    66181 acctctgttg gtatcaggca agctacaggt ttcttagctt taaaagctaa aatgacccct
    66241 tttgaagaat tgatcagtga agaagaattg actggtgggg cgacaaatga agaatataat
    66301 caaatgcaac agtattatat ggattcttcc caaaatgcag caatcgaaca agcgttaaaa
    66361 cttgcagaca agccttataa aatggaattc aaaggcgtat atgtcatgag tgtagagaaa
    66421 acatcgaatt tctttggcaa gctttcagtt ggagatacag taacaaaagt agacgggaaa
    66481 agctttcaaa gtacagaagc atttatggat tatgtaaaaa gccaaaaagt tggacaaaca
    66541 atcgaaatca gttatttgca taatggtgaa gaaaaaacag cttctggtga tctgatcgag
    66601 ttaccaacag ataaaaaggc aggaataggt atcacgctta ctgaccatac cgagatcgaa
    66661 tcagatacag atgttcgtat taattctggc tctatcggtg ggccatcagc gggattgatg
    66721 ttcactttag aaatctatga acaagtcact ggtaaaaact tgcgacatgg taagcaaatt
    66781 gcaggaactg gaacgatcaa cagtgaagga gaagttggcc gaatcggagg aatcgataaa
    66841 aaagtggcaa gtgcggataa agctggcgta gagattttct ttgcaccaga tgatacgatt
    66901 tcagacgatg ttaagaaaga atatcctgaa ataaaaacca actacgaaga agcaaaagct
    66961 gccgctaaaa aattgaattc ctcaatgaaa atcgtaccag taaaaacagt acaagaagcg
    67021 cttgactatc tagagaaaat gaaatgaaac taaataatta aagaggggtt gtgacacgag
    67081 ttctgtcaca acccctcttt ttcgtcaaaa atcttcacga taaaaataaa aacaaaagaa
    67141 aaaattgacg taattagatg ttgaagggac gattttgcca gagctcactg tttcttcaat
    67201 tttaaatgaa aggagtaatg aatgattttt actggtcatt ctttgaaaaa agaacaatga
    67261 tagaaaaaat cagcaagaaa atactagctt cacccaaatt gatcatttgg atgtctatga
    67321 tagttcttat cttttgtatc gcaagtggtt ttttattatc aaatttgcta ttttatagag
    67381 aaacagaaga gactgctgca aaagaaatac tttcttcgtt tagttccagt ggagaagatc
    67441 catcagctga aggaaacgat gtagaagagg atgctcgtcc aaaggtcatg tacaccgata
    67501 tcaaaggaag tgtgaaggag cctggtatct attccttttc ttcagaagaa cgggtctatg
    67561 atgtactaaa gcgtgcaggt ggattattag aagaagcgga tagcgatcga atcaactttt
    67621 ctgcgaagat agaagatcag caagtcctat atatccctgc tgtaggtgaa gagctgccag
    67681 aacatcttga tcagttggca tcctcggaag gaaaacagcc tacagcagat tccgagcctc
    67741 ccaaaataaa tatcaataca gccactccat cagaacttca gcagattcct gggatcggat
    67801 cagtcaaagc gcaagaaatc attcgattta gagaagaaaa cggatccttc cagaaagtgg
    67861 aagacctgca ggagatttct ggtatcggtg aaaagacagt tgaaaaacta aaaaacttcg
    67921 ttacaattaa atagaatgat tcaaaatcga ctggcacgag caataaatgg acgctaatgg
    67981 atactaagaa taatccaatt ctaagagctt ggcaggacga ggaggtagta tttttggata
    68041 ggaaatagct tgattgttcg caaagaaaca ttaaaaaaac caatgctgaa tgtctatctc
    68101 caaaataaaa tatctgggat tcatattatg aatacggctg tcagcggcaa taacagtcaa
    68161 gctctacgag aacgctttgc caaagatgta cttagctata cagcagataa agtatttatt
    68221 ctcattggga cgaatgatct agcagagcat aaacaacttt ctaaagaaac gtaccaaaaa
    68281 atctgcagtg gatgatagtt cagctgaaaa aagactatag ttctgatcat gctttcttta
    68341 tcacgccacc agcagtcgat gagacaaaac aaaaatatcg gaataacaag ttgatcaaag
    68401 aatatatctc tgttctcaca gaagtagcaa aacgccatga ttgtgaagta tcgattttta
    68461 tacggaattt cttgaacaaa tggattcgaa gaatttttat aatgggctaa tggatgacgg
    68521 acttcatttc ggcagtgaag ggtaggatct tttgtcagac aggatgattc gttatattta
    68581 aagaatattt tgtttaagca atgagtactt tttaatcaac ttgaaaaaac ggaggaatat
    68641 aaaacatgtt agaaaaatct tcaaaagcat gcgatacgaa taaagaaaaa gttactgata
    68701 agtcacataa tgaacgcatt ccttgggacc agtactttat ggctcaggca gtactgttat
    68761 ctttacgtag tacgtgtaca cgtttagaag taggagcgac actcgttcga gaaaaaagga
    68821 tcattgctgg cggctataat ggagcagtca gtggagatgt ccactgcata gatgaagggt
    68881 gttacgtcgt ggatggacac tgcttgcgaa cgatccatgc agagatgaat gcactcctac
    68941 agtgtgcaaa acttggtatc ccgacggaag gttcagaaat ctatgtcaca cattttccat
    69001 gtttggcctg tacaaaggct ttgttgcaag ctggtgtgaa agggatcaat tatctccatg
    69061 actatcgaaa tgatccttat gcccaagcgt tgatcgaaca attaggtgta tctgtacacc
    69121 aagttgcttt agactcacag catttttcaa aacttcaaaa tgaattaaca ggaaaacatg
    69181 tctagcgttt tagaaaggca tgttcgaaat cggttgattt ttccggcaat tacgtcgatg
    69241 attatctgtt tgttgtatta cactgacaat tggggttatc gtttgcttct tgccgga
//
LOCUS       DAPBBR010000008        64197 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPBBR010000008 DAPBBR010000000
VERSION     DAPBBR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.008"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(21..251)
                     /locus_tag="RD488_000533"
     CDS             complement(21..251)
                     /locus_tag="RD488_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656633.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="RD488_000534"
     CDS             complement(687..1253)
                     /locus_tag="RD488_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7656634.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="RD488_000535"
     CDS             complement(1253..2209)
                     /locus_tag="RD488_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDT7656635.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="RD488_000536"
     CDS             complement(2209..2865)
                     /locus_tag="RD488_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDT7656636.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="RD488_000537"
     CDS             3235..5253
                     /locus_tag="RD488_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7656637.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="RD488_000538"
     CDS             5680..8094
                     /locus_tag="RD488_000538"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDT7656638.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="RD488_000539"
     CDS             8442..9995
                     /locus_tag="RD488_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7656639.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="RD488_000540"
     CDS             complement(10376..12160)
                     /locus_tag="RD488_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656640.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="RD488_000541"
     CDS             complement(12175..13896)
                     /locus_tag="RD488_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656641.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="RD488_000542"
     CDS             13996..14757
                     /locus_tag="RD488_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7656642.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="RD488_000543"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="RD488_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..19786
                     /locus_tag="RD488_000544"
     CDS             16664..19786
                     /locus_tag="RD488_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7656643.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKA
                     NRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVY
                     QLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQG
                     AVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIE
                     KEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFI
                     SIKFRKKRNI"
     gene            complement(20210..20380)
                     /locus_tag="RD488_000545"
     CDS             complement(20210..20380)
                     /locus_tag="RD488_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7656644.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(20574..20753)
                     /locus_tag="RD488_000546"
     CDS             complement(20574..20753)
                     /locus_tag="RD488_000546"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656645.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(20763..20987)
                     /locus_tag="RD488_000547"
     CDS             complement(20763..20987)
                     /locus_tag="RD488_000547"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656646.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            21140..22252
                     /locus_tag="RD488_000548"
     CDS             21140..22252
                     /locus_tag="RD488_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7656647.1"
                     /translation="MTVKNKSKKKGRQQVDFYQYLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(22330..22623)
                     /locus_tag="RD488_000549"
     CDS             complement(22330..22623)
                     /locus_tag="RD488_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDT7656648.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            22791..23105
                     /locus_tag="RD488_000550"
     CDS             22791..23105
                     /locus_tag="RD488_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HDT7656649.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            23126..25105
                     /locus_tag="RD488_000551"
     CDS             23126..25105
                     /locus_tag="RD488_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7656650.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            25118..25444
                     /locus_tag="RD488_000552"
     CDS             25118..25444
                     /locus_tag="RD488_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HDT7656651.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            25460..25978
                     /locus_tag="RD488_000553"
     CDS             25460..25978
                     /locus_tag="RD488_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656652.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            25978..27330
                     /gene="celB"
                     /locus_tag="RD488_000554"
     CDS             25978..27330
                     /gene="celB"
                     /locus_tag="RD488_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7656653.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(27414..28919)
                     /locus_tag="RD488_000555"
     CDS             complement(27414..28919)
                     /locus_tag="RD488_000555"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDT7656654.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(29011..29601)
                     /locus_tag="RD488_000556"
     CDS             complement(29011..29601)
                     /locus_tag="RD488_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7656655.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTIWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            29780..31426
                     /locus_tag="RD488_000557"
     CDS             29780..31426
                     /locus_tag="RD488_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7656656.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            31475..32194
                     /locus_tag="RD488_000558"
     CDS             31475..32194
                     /locus_tag="RD488_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7656657.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            32673..33620
                     /locus_tag="RD488_000559"
     CDS             32673..33620
                     /locus_tag="RD488_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7656658.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            33632..34552
                     /locus_tag="RD488_000560"
     CDS             33632..34552
                     /locus_tag="RD488_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7656659.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            34593..36050
                     /locus_tag="RD488_000561"
     CDS             34593..36050
                     /locus_tag="RD488_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7656660.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            36395..37009
                     /locus_tag="RD488_000562"
     CDS             36395..37009
                     /locus_tag="RD488_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7656661.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            37002..38726
                     /locus_tag="RD488_000563"
     CDS             37002..38726
                     /locus_tag="RD488_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7656662.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            38723..40174
                     /locus_tag="RD488_000564"
     CDS             38723..40174
                     /locus_tag="RD488_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7656663.1"
                     /translation="MSVYQVLLVDNEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(40647..42800)
                     /locus_tag="RD488_000565"
     CDS             complement(40647..42800)
                     /locus_tag="RD488_000565"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HDT7656664.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(42802..43848)
                     /locus_tag="RD488_000566"
     CDS             complement(42802..43848)
                     /locus_tag="RD488_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7656665.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            43998..45287
                     /locus_tag="RD488_000567"
     CDS             43998..45287
                     /locus_tag="RD488_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HDT7656666.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            45300..48002
                     /locus_tag="RD488_000568"
     CDS             45300..48002
                     /locus_tag="RD488_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7656667.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            47987..48844
                     /locus_tag="RD488_000569"
     CDS             47987..48844
                     /locus_tag="RD488_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7656668.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(48915..49814)
                     /locus_tag="RD488_000570"
     CDS             complement(48915..49814)
                     /locus_tag="RD488_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7656669.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            49983..52154
                     /locus_tag="RD488_000571"
     CDS             49983..52154
                     /locus_tag="RD488_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7656670.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            52222..52563
                     /locus_tag="RD488_000572"
     CDS             52222..52563
                     /locus_tag="RD488_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7656671.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(52839..54593)
                     /locus_tag="RD488_000573"
     CDS             complement(52839..54593)
                     /locus_tag="RD488_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656672.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(54604..55440)
                     /locus_tag="RD488_000574"
     CDS             complement(54604..55440)
                     /locus_tag="RD488_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7656673.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(55442..56125)
                     /locus_tag="RD488_000575"
     CDS             complement(55442..56125)
                     /locus_tag="RD488_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HDT7656674.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(56284..57678)
                     /gene="uxaC"
                     /locus_tag="RD488_000576"
     CDS             complement(56284..57678)
                     /gene="uxaC"
                     /locus_tag="RD488_000576"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDT7656675.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(57717..59216)
                     /locus_tag="RD488_000577"
     CDS             complement(57717..59216)
                     /locus_tag="RD488_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDT7656676.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(59209..60630)
                     /locus_tag="RD488_000578"
     CDS             complement(59209..60630)
                     /locus_tag="RD488_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDT7656677.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(60690..61682)
                     /locus_tag="RD488_000579"
     CDS             complement(60690..61682)
                     /locus_tag="RD488_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7656678.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            61914..64112
                     /locus_tag="RD488_000580"
     CDS             61914..64112
                     /locus_tag="RD488_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656679.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
BASE COUNT        20693 a        11414 c        12952 g        19138 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtttaac
    18901 tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat atcagctggt
    18961 agaaactcaa gcgccaatag ggtatgaatt agatgcgaca ccaatcgagt ttgagatcga
    19021 aagaagtcag acagcggtgg tagaattgac gaaagcaaac cgacttacac caggcggtgt
    19081 cgtgttgaca aagatcgatg accaaagcgg ggaagtcctg caaggagctg tttttgagtt
    19141 acaagatgcc aatggaaccg ttctgcagtc aggtctaacc acaggagcag atggaaaact
    19201 ggcgattgac ggcttagcac caggagtgta tcagctggta gaaacccaag cgccaacggg
    19261 gtatgaattg gatgcgacac caatcgagtt tgagatcgaa agaagtcaga cagcggtggt
    19321 agaattgacg aaagaaaatc gacttacacc aggcggtgtc gtgttgacaa agatcgatga
    19381 ccaaagcgga gaagtcctgc aaggagctgt ttttgagtta caagatgcca atggaaccgt
    19441 tctgcagtca ggtctaacca caggagcaga tggaaaactg gcgatagatg gcttagcacc
    19501 aggagcatat cagctggtag aaactcaagc gccaacgggg tatgaattgg atgcgacacc
    19561 agtaactttc aagatcgaaa aagaacaaga agtggcgatc tttttaacaa aagagaatag
    19621 aaaagttgct gatagctcag atataagagg aaacaatcca acaagcagtg gaaataagca
    19681 tcttccaaaa actggagaaa ccatcattag ccagtttata ttgtcaatat tgggtgtgct
    19741 acttgttttc atcagtataa aatttagaaa gaaacgaaat atatgagcta aaataaaaaa
    19801 ttgaataagc atagttttta aaatcaacta gtacccatca attgaatgga aactaccgat
    19861 tttagaaggg gtatacaaac aaatattagt atcggagtag agaaggttga acccaaccag
    19921 taaataagta aagacaattt tgtgctgcgt tgagaagtga aaaataaacc tttgtagtaa
    19981 tactagttaa taaaaaatat acaaaaacac tgcgaaaatc attcttgagt ttcgcagtgt
    20041 tttttgccta atgactcaag tttattgggt aatactttga ttttctttct acaaataatc
    20101 agcgatcagt tgtaattttt tctctagttt taatggctct ttgtcaataa ggagaaaaac
    20161 aagtcgggtc ttttgtctcg gaaagcttca accaactcgt gaataaaggt tacgcctcct
    20221 tgaaaggcgt ggaaaaacca agtaatcgat caatcaccaa tttcgcattt ggtagaacat
    20281 gtttggtgag ctgaaagtag gtggcgttca tgtctgtaac taagaattct atttctttag
    20341 gattagtgca gctaaggaaa tagtttgtta atcgaggaat tttttgtgta ggtaaatttt
    20401 ctcgattaat ttttctgtct cgccatccgc ggaaataaaa ctcagtttat cctcaacgga
    20461 aacgtgagaa cgaaattcac aaccctcaac actcaagaca gaattctttt ggaagacttt
    20521 ggtaaatagc ttctcaactc tttcaatgtg cgaataacgg ttgtcaaaga tacctaacaa
    20581 cttttcgaaa taaaaaataa cgacactttt tcagtcagta aagaagtgat tttatgtctg
    20641 acatgatttg aaatcgagtg ccttggacgg ataaaataac tttgagcgtt ccaatggctt
    20701 cgacagtttt tacaggtata gcgctgcttt tttaggcgta taaccattgg catatgatta
    20761 tattattcaa agtggacaat ggtttccttc ttcttgtttt tcaccaccat taatttccta
    20821 tttccatcta ccacagcaga accacaattt ctacagacac atggagcagg gaagagaact
    20881 gcagcaacga tcaatgtttt tttcttctgt aaggtttcgt aagagacctc tgtaatcatc
    20941 aaatttttgt ctattgatct cagaattttt ttgatagaac cattcataaa gcatatcgtt
    21001 ctctcagttg tttattttgt ggtgatttaa tcatacaaga aaacgatatg tttttttata
    21061 aaaacatgaa taggaaaaat agttgacaag aaaatgacaa cgccatatga tgttccatag
    21121 tatttacaac ctgtcataga tgactgtaaa aaataaaagt aaaaagaaag gacgacaaca
    21181 ggtggatttt tatcagtatc tacaactaga tccgtttatt ttaaaacaaa aaatacgaga
    21241 agcagcttct aaaaaagaaa agtgcatgta tatttgttca ttgtttttac gatcattatt
    21301 catcgtattg tttgccattt gttttatcat tataattaca acattatttg aatcgaagca
    21361 taaaccatac gctgtggttt tattctgtat gttgatgagt attcgttttg ttgactttgg
    21421 ttataagatt tcccattcga tcataggttt agcaatcgtc atgttctcac tattagtagc
    21481 accgtatgtc cagctgatca aatggtcagt tatgggcatg ttgattcatt ttattttact
    21541 aagcagcata ttaatggcaa ccgctagtga tcccaaaatg gggaatgctt ctttgtacgg
    21601 cttttcatat ctctttattg tttattcgtt acctaaagat tcgttgaaca agaatttctt
    21661 tacacaaaca agtagcttat tatttttgtt tttttgttgg ttttcagttc tcctttacag
    21721 aaaacatcga gaaaagaaca aagacaaaag cttgtttaaa gagatttttt tgaaaggcat
    21781 gtattcgcag gaaaaaattt ggatgctcat ctatgcattt ggcattagtc ttttgatcgt
    21841 tgcaggagag tatgtccctt ttcagcgatt gatgtgggca gggtttgcat tttcttctat
    21901 tgtatctagc tatggattga tgtcgattgg tttcaaagaa cgagcagtag accgaatcat
    21961 tggctcattg attggatgtg ttttatttat tggtatcagc caatttattc cttttaactg
    22021 ggtcggtata ttaggtggtc tagctttagg tgtttgttct acctatagat ataaaacagt
    22081 ttttaattct tttggtgctt tggcaatcac tgccagttta ttcggggttc caggagcagt
    22141 aacgatccgc atttttgaga atatccttgg ggtatgttta ggaatcatgt atattggggt
    22201 gactgaaata cttatccgaa aaataagaga aaaacacggt ttgaatcatt agatgagatc
    22261 gaataaaaaa taaggaaaaa gtgaagatac acatggatga taaattgcta tcattccatg
    22321 tgtatctttt tacggtaaat cagtgaaacg ttcgactttc atttttaatt tatacttttt
    22381 acggagttcg tttatttgag ccatcatttc ggatttgtga tgcttttcga ttgcttcttc
    22441 atctttccaa cggtcgatca gtaaaagaga ttctggatct tctagtggaa agtaatagtc
    22501 atatttctcg tttccttctt ctgcacgaat cgctttgaca atgtttcttt cgaccatttc
    22561 ttctgcaaat tttctggctt gtccatttgt acttgtatac aaaatattca ctgtgatact
    22621 cactaaatcc cctcctgaaa aaattctatc actagtatat cacggtgcca gaaattatta
    22681 ttcaagatat gatacacatt ttttccgcaa tgctacggaa atatatattt tgaatagaaa
    22741 acgcttacaa gatatgcttg gtttataaaa ataaaaggag tgattgattt atgaaaaaag
    22801 cattgattat ttgtgcggca ggaatgtcat cctcgatgat ggcctcaaag acaacggatt
    22861 tctttaagca aaaaagagaa gaggtactcg tagatgcagt ttcagctaca gaaggcgata
    22921 atatgattaa gaatagtgat tttgatttat ttctgatcag cccgcaaacg acgatgtttt
    22981 tggataaatt caaaaaatta ggagaatctg ttggaaagcc tgttgttagt atccctttcc
    23041 aagcgtatgt cccaatccct acaggcatcc agaagttagc agaggtgatc gaagagaaca
    23101 tatgatggaa taggagtgga tgataatgaa acagaaggaa aaattgctgt tgagatattt
    23161 gattgatcac aagaaggagt atgtcaccag tcaacgttta gcttctgaat tgttattatc
    23221 tgatcggaca atccgtaatt acttgcagcg gatcaaagag ttagtagaaa aaaacggagg
    23281 taagatcatt gctaaaccag gttatggcta ccaactgcat attttacaaa gactgacatt
    23341 tgacttgttt ttgagtcggc aagaaatagt acctggatat gctagagaac cgcaaggatt
    23401 ttatgagtcc gaagatcgac aaaagtatat attgaaccaa ttgcttttgg aagatgccat
    23461 tctttttatg gatgatttgg cagaagagct ttatatcagt cgttccagtt tgacaaagga
    23521 catgcaagaa atcaaggagc gattgattcc atattcacta aaaatcgttt ctaagcatgg
    23581 tcaagggaca tggatcgaag gggaagaaag aaatcgacgg cattttatca tggatacttt
    23641 ttttggaaac cattatggaa attcattgaa agaatattta gggcaaagcc gttttttccc
    23701 agacatcagt tttgaagagc tagtcattat cattctcgat gaaacaagag aagctaagtt
    23761 aaaagtttcg gattttatca tacagaatct gactttacac ttggctttgg ggatcaaacg
    23821 gctccgagaa gggtttgaaa tcaaggaatt aggcatcgaa caagaagttt ctaagcgagt
    23881 agagtatcaa gtggcgcagc ggatcgttca acgtattgag gtaatcgcag gtgtatcgtt
    23941 tcccgaagaa gaaattgctt atttgacatt acatctcatg gctaagtcga atcacaaaga
    24001 aaatcaaaat gatcaggaac tatcaaagga attagcgaaa gttctgaaaa gattgtctca
    24061 ggaatttcat ttttcattag tagaggatct ccagcttttc aatggactac tcgatcattt
    24121 gtcaccgatg atgattcgat tgagccgagg tattcgcatt gagaacccat tgactgagga
    24181 gataaagaaa gaaaatccca aagtctttga cgcagtaaaa aggcatttca gcaacatgcc
    24241 ggctttgaaa aactatacca tcaatgaaga tgaatgggcc tatttggctt tgcatctcat
    24301 ggcggcattg gaaaaagaaa gagctgcgca taaactacat gcattgatta tctgtgcaac
    24361 gggttacggc agtgcccaac tattaaagaa tcgcgtagtc agtgaattcg gtaaaaatat
    24421 tacagtggta agtgtaaaag gctattatga gatcaatgaa acaactttaa aaggaatcga
    24481 cctgattatt tcttctattg atctttcgac aatgtttttc aaaattccag ttttacatgt
    24541 cagtattttt ttgaatgaag atgatgttcg taaaatacga aaggtagttg gagaatctat
    24601 accctatcat tcctcagata gaccgatacc agcattttct ctacagcaaa aaaagcagat
    24661 ttacaccgaa cagttgtctg aaaaattttt caagacttat acgtacgaac cgaaaaagga
    24721 agaaattctt catgatttgc tgcaaaagct gagcataaat gaagaagaag gatatataag
    24781 agaaatgcga aagcagatcc agcaacgtga aaatatggga caaatcatat tcagtgatac
    24841 agtggcagtc ccacatcccg ctgttccagt tggaatcgaa acaaaggtag ccgttgcatt
    24901 gattccttct gggatgcagt gggatcaata tcaagaaatt cattttgttt ttttagtttc
    24961 gccttcttat gtcgaaaatg aaggaattac ggtcgtgact aaagcaatcg ttaggttagt
    25021 tgaccagcta aaagtacagc aggaaatctt agctgaacct atttttgaga atttcagcag
    25081 taaatttatc aaactgatcg aataaggagg aaaacagatg gctgaaaaaa taaacagtga
    25141 aacactacaa gtgacttctt ttgatatcat tttccatagc ggaaatgcac ggacactgat
    25201 acatgaagca tttcgctcga tgcgtaaaga gatgtttgaa gaagtagaag agaagttgcg
    25261 acaagcaaat gaagagattc ttcatgcgca tcagtcacaa actcaacttc tgaaagaata
    25321 tgccagcggg acaaaaatag aaatggaaat tatcatggtc catgcacaag atcatctgat
    25381 gacgacgatg acattattgg aagttgcaca ggaaatgaat tatttgtatc aaaaaaataa
    25441 atagaaagga aggatcattg tgcaggatac agtaaaaagg aaaatcgaat tagaaaaaaa
    25501 gcaacttagt ttgaaaaaca tgtatttcaa tcgttatcta atcgtacgtt acctgactgc
    25561 ctttttcttt ttcatgaaca tgcaatggat gattctgctt ctatcagcta aaagtttagg
    25621 aagtagttta ccgatgattc tgattttagc tattttgcct gcagtaggag aacaagtaaa
    25681 gctttatcga aaacaccaaa cgaacgttcc atggacaaag tggtattttt tgttccagag
    25741 tgtctttaat ttattagtga ttccagtgtt gtttacctca ggatttacat tcttgtatcc
    25801 ttttatggca aataacaatg gaggacagtt atttgttttc attcttgttg taagcggtat
    25861 ttttgccagt gcatttatac agtatcgttt aaagaaaatt tcactcaacc aagaccaaca
    25921 gtatatccgt attaaacaat atgaaaaagc gttatattta ggaaaggaga ataactaatg
    25981 tttgattttt tgcagaaata cctgatggga cctatgggga aaattgcgca acttaaaatc
    26041 gttcgggctg tcatggcagc ggggatggct tctattcctt tcacgattgt aggctcgatg
    26101 tttttggttt taaatatttt gccattaccg ttcccatttt tagaaggatt ttttaatgca
    26161 acttttttca aagttagtga cttgtacatg atcgtcaata caatgacgat ggggatttta
    26221 tctatttact ttgccattgt gtttgcttat gaattaacgt caattgaacg agatgaacaa
    26281 aaattaaatg ttaatccgct cacgggggca ttactatctg tttttgcatt ctttatgtgt
    26341 atccctgaat tgatcatgac tgatggtaaa atcagcttga ttgcttctat caatgagaca
    26401 gaaactgtag taaatggtat taggatgggc tcttttgtcg aacgtttagg aacttcagga
    26461 atctttacag ctattattat gtcgattatt gcggtcgaat tgtattgtat gtgtgtcaag
    26521 agaaattggg tcataaaaat gccagatgtt gttccgccag gagtttctcg ttctttcact
    26581 gctctgatcc caacatttgt cattgcgttt gtggtgatga tcatcaatgg attattagtt
    26641 gcactaggaa cggatatctt caaaatgatt gctatcccat ttgggtttgt tacgcagttg
    26701 acgaatacat ggcttggtgt catggtgatt tatttcttga tccatgcatt gtggatcgta
    26761 gggatccatg gagcgaatat catcacttct ttcttgaccc cgatcgtatt agctaatatg
    26821 gcagctaacg cacaaggcgc aaattatccg ttggcaggag aattcaacaa ttcttatgta
    26881 accgttggtg gatcaggtgc gactttagga ttgatcatct ttattgcatt cctcgcgaaa
    26941 tctgatcagc tgaaagtgtt aggaaaagcc tcacttgtac caggattatt caatatcaat
    27001 gaaccaatca ttttcgggat gccaatcgtc tacaatccct atttagcggt tccgtttttc
    27061 ttagctccga tggcttctgc tacactcgct tattttgcca ttcggctgga aatcgtcaaa
    27121 ccgatgcttg cacagatgcc gtggccttca ccagtcggga tcggagcatt tgttggtagt
    27181 ggtggtgatt ggaaagctgc tgtgttagca gtcatttgtg caatcatcgc attcattatc
    27241 tggttcccat ttatcaaatt ctatgataat aaattattaa atgaagaaag agaaaaggca
    27301 gcagaattag ctagtgaaaa gttaaaatga tttctaagaa aaaaggaact gtgacaaaaa
    27361 atcacagtcc ctttttttct tagaaatggg aaaccactag tatataaata ccattattct
    27421 tcaatcaacc gcttcacgat tgcataatcc ccttcataag gttcatctac accattgatt
    27481 ttttgatagg gatccacgcc ttttcccgca ataacgactg aatcttgcgg agcgctttct
    27541 gctaaagcgc gtcgaatcgc ttcaggacga tccatttcat aatgaacgat caaatctgga
    27601 ttagtaattg cttcattgat ttcttccgcg atttttttcg gatcttcaaa tgctgggtca
    27661 tctgccgtca aaaaggcgat gtcagctgtt tctgatagca cttttccaaa atcatgtcga
    27721 cgggagattg ctttgtttcc tgggctgcct aatacaacaa ttacacggcc atctggatgt
    27781 tcatttttgg caaatttcag caatgttttc aagcttagat aattatgtgc atagtccaca
    27841 tagacatgcg ctccattgga ttggatcaat tgatccattc ggcctggtac acgagcttct
    27901 tttaatccgt cttgtgcatc ttgactggag gcacctgtta gtgctgcggc aatgatcgca
    27961 ctggctgcat tttcttggtt gaatcctcca gccagcaaaa tatcataagc agtatcgcag
    28021 atagctaagc gatcttcatg agaagataaa gtaaaaccgt gagtaccttt atctgaacgg
    28081 atcacttgat aattgctttc ttccgaacga ccataagtga tcgttggaat ctggaataga
    28141 tcggctgttt ccctaagtaa atcaaaatag tcactttcat gatttaaaac aactgttttt
    28201 gaattcaaga tcaattgtcg cttgcaatag aaatagtcat caaatgtcgg atgttcgatc
    28261 ggactgatat ggtcaggcga gatattcaag aagattccga catctaaagt caagccgtat
    28321 acgcgttgtg ttttgtaagc ttgtgaagaa acttccatca ctagatgagt cataccattt
    28381 tcaactgctt ctgacatcat acgatataaa tctaatgact caggcgttgt caaatgggat
    28441 ttgaaatatg ttttgccatc taacgttgta ttcatagtag aaagcaatgc tgttttttta
    28501 tttgttgtgt gatccaagat tgcttttgta aagtacgcag cagttgtttt accttttgtt
    28561 ccagtgaatc cgatcacttt caatttattt tgcggatagt cgtaaaaagc catagcaaga
    28621 agcgccattg ctttacggat atccgttacg atgattccta ctgctgaatt ttcgtatggt
    28681 tgttctgata cataatattg aataccctgt tcgattgctg aatccaaata ttcttctttg
    28741 aaattcattc ctttacagaa aaacaaagta gaagcatcag cttttcttga atcataactt
    28801 aactgaagaa attcagcttt ttctggtaca tcaagatgcc agcctcttgt tgaaacaaat
    28861 tcttttaata gattttcttt taatagtaaa tgacggatgt cttctaaaga gaagctcatt
    28921 gattgatccc tcgctttatt caatttcttg gtttattata gcacactctt tttaatatat
    28981 cgtttgtttc cgctatgaca aaatccagct ttattcaaat tttcttgaca caggggacaa
    29041 gcggatgagt attttcataa acaatgaact gactgtaata gataggagaa cgaatagtgt
    29101 ctccaacaat ccaaaaacat aataattcaa aaagacgata agactattgg taagtaaaag
    29161 tccttgcggc attggaagcc gaaaaaattt gtggaaaata atcggcggta tcgttatacc
    29221 gccatttgag gccccgactg tgtacaatgt gtaaacccca agactgaaca aaagacttcc
    29281 tgaaatcagt gaaaagaaat gtgaggagat catttccact tttggaacaa tctctaaaac
    29341 aacaggaaaa agcagacttc ccgctacagt cttaaaaaat actgattttc ctaataggac
    29401 agcggctaga agcagcatca taagattgat gctccaaata gtaactgagc gttggataga
    29461 aaaggccgtt tcaactaaat gtccgatggc gcccactccg gcggaagcta tatcgtgagg
    29521 gagcaagaac caattcaatc caactgtgat aaagaaaaga cctaaaaata taacgggtag
    29581 tttttttatt tcttgtgtca ttgatatctc ctataaatgt tagccataaa aggctgtata
    29641 tttctttact ttaccaaaaa aacgaaaccg aattcaaaaa aacaattgtt cttataaaag
    29701 ttatataaaa tcgattgcca gtttctgttt taccaattaa aatgatagta atgttttgta
    29761 gaaagttgga atctgaccga tggataatca aagaaaacca gcattagatc aattaacacc
    29821 gcaagaaaaa atggcacgag gctctgcttg gatgaccgcc agtaatatca tttcaagatt
    29881 gctaggcgct gtctatatca ttccctggta tgcttggatg ggcgaaaatg ctaaggctgc
    29941 caatggatta ttcaatatgg gatacaatat atatgcattg tttctactga tctctacagc
    30001 aggaatacct gctgcgattg caaaacaaac tgcacgctat aattcattga atgaatatgg
    30061 cacttcacga cgattattta tccgtgcatt acagatgatg ggcgggttag gcctgttgtt
    30121 tgctttgttc atgtacatcg cctctccttg gctagctcat gcttctggtg gcggagaaga
    30181 actgattcca acgatgcgtt ctttgagtat cgctgtattg gtttttcctt gtatgagtgt
    30241 gatacgaggg tatttgcaag gcaatcaaga aatgatgcct tatgcgctgt cgcagattgt
    30301 agaacaggtg gcacgtattt tttatatgct attggctaca ttcatcatca tgaaagtcat
    30361 ggatggtgac tatgtgacgg cggtcacgca atcaactttc gcggcattta tcggtatgct
    30421 agcaagtatt cttgtccttt tgtatttttt gaagaaacat caagcgtata catcggcgtt
    30481 tattcactac agcgaaaaca aaataaatat tgcaacgaag gaattgttgt tagataccgt
    30541 taaagaagcg attccgttta ttattgtggg ttcaggggta acgatcttca aattagtcga
    30601 tcagttcact tttatgaaga tcatgtctgc atccaccgag tattccaatg cacagttact
    30661 ggatcttttt tcgattttta gtgccaatcc agataagttg acgatggtag ttattgcatt
    30721 ggcaacatcg atcgcgtcta ctgggttacc gttgattaca gaagctgtta cgttgaaaga
    30781 tcgagtaggt ctggcaaaat tgacaagcgg aaatttacag ttgttttcat tttttatgtt
    30841 tccggcgaca tttggtgtta tgttacttgc ctatccgcta aatacattat tttatacacc
    30901 ggattctcta ggaagtaatg tactgatcca agcaagtttt gtaggactct tcctaggact
    30961 atatatgcta gtttccaaca tgctgcaagg aatgtttgaa aacaaggcgg caattaatta
    31021 tttggttatt gggtttctag tgaaactcct tcttcaatac ccagccattc gtttatttga
    31081 agtatacggc cctttattgg cgacaatgat cggatttgct gtgtcttgta ccttgatctt
    31141 aaagagaatc catgaagtag cccgctttaa accaagtttt gtctggcgca ggacattgct
    31201 gatctttatt cttaccttga ttatgctttt ggcttcgtgg atcacaaaga tgatttttgg
    31261 tgctttttta aacgaagata gcaaattcca gtctctattg ttgattcttg tagtagcagg
    31321 tataggggct ttagtgtatg gttatttagc tttgaaaatc cgcttggcag aaagactact
    31381 aggaccagga atagcgcgtt tacgacataa attaaaaata aaataagtga atcagaagag
    31441 ctagattgat gctcttttga aatgggggaa acgcatgcgt ttagataagt ttttagcaga
    31501 tatgggactt ggcagccgca aagaagtcaa aggattaatc aaaaaaggaa cgatcgaagt
    31561 caatggacaa gtggtgaaaa gcgataaagc gcaagtaaat gaattcgaag atgcggttac
    31621 ttatttagga gaaatcatta cgtatcaaaa agatttttac tacattttgc ataaacctgc
    31681 aggagtcatt tctgctactc aggataatca tgatcaaacc gtaatcgatt tattggaaga
    31741 ccaggattat cgggaagatc tttttccagt cggccgatta gataaagaca cagagggcct
    31801 cttgatttta acgaatgacg gggtgtttgc ccatcagtta ctatcaccta aaaaacatgt
    31861 ggagaaagaa tatctagctg aggttagcgg tataatgaca gaagaagata tccgtttatt
    31921 tgcagaagga ctgattattg atggcgatga gcagacattg ccggcaaaac tccaaattga
    31981 tcaagtagat caagagacag aaacttcaat tatccgtctg attttgcatg aaggaaagtt
    32041 tcaccaagtt aagcgaatgg tcaaagcagt aggaaaagaa gtcttatatt taaaaagaat
    32101 ccgtatggga aaattttggc tgcctaaaga tttgaataaa gggcaatatc gacccatgac
    32161 caaagaagag ctagaacaag tgagagaaaa ataattgaat ggatagctaa aagaataagc
    32221 agagtagttg tagcgccatc tgaaaagcag acttgtccgt ctgactttcg gatggctttt
    32281 ttgtgaaatt tcggcttatt tccgtagaag ctacttctgg aacaccgttt gttcggaata
    32341 agggactgtg acaagacttt tgttacagtc cccattgttc cttgtgactc agagttagat
    32401 agtaaggaca cgatctccct aatactcagg ccaaaacgct gaattcacaa cctctgataa
    32461 acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaat atgaggaact
    32521 attttcccgt ttttttctct aatactcagg ccaaaacgct gatttcacaa cctctcctat
    32581 actttgtttc attttcccta tactttgttt atttattctc attattgaaa gcgctataat
    32641 tacgttgcga atgaatcgaa aggggttttt agatgaaaaa acgaaagggg ttcaatcatt
    32701 tttttatgaa tctatggcgt tataaagcac ttgtcctgat ggctgtaccg ggtatgcttt
    32761 ggatgatttt tttcttttac atacctgtaa tggcgaatgt cgtagcattc aaaaattttc
    32821 atatttcagc agatgggttc ttggctagct tgagggaaag tccttgggtg ggttgggaaa
    32881 atttcaaatt tttattttct tcggatcaag catttctcat cactaaaaat acaattttat
    32941 ataatgtagc atttatcctt ttgaatctgc tgatctcagt cgtatttgca atcattatga
    33001 gcgagttgag aaataaacga ctcgttaaag tttatcaaac gatgtcctta ctaccttatt
    33061 ttctatcttg ggtcattatc agttactttg tttacgcttt tttaagtcct gacaaaggaa
    33121 tattcaatca gtggatcact ggacatggag gagaagctgt caattggtat aatgaaccga
    33181 aatattggcc gtttatcttg gtgttcattg gtacatggaa agggattggt tataacagca
    33241 ttatttactt tgcatctgtt atgggaatcg atccgactta ttatgaagct gctatggttg
    33301 atggagctag caaatggcag cagatcaaac atgtgacgat accacaactt attccactaa
    33361 tgacgatttt aacgatttta gccgtaggaa acattttccg agctgatttt ggcctgtttt
    33421 ataacattcc taggaattcc ggtgcattat atgatgtgac tcaagttttg gatacgtata
    33481 tctacaatgg cctgacatcc acaggagatt ttggtatgac ggctgctgca ggactttacc
    33541 aatcagttgt cggctttgtc ttgttgatga tcacaaatac gatcgcccga cgttttgata
    33601 gcgattctgc attattctaa ggaggaaaaa aatgaaaaaa aagaaagtgg agagagtcca
    33661 agtccgctct ttcaataaga cggctaattt tttctctaat ataatgattg cactctttgc
    33721 tatttcctgt attttgccat ttatatttgt tatcgccatc tcttttaccg atgagtccat
    33781 attgtcgact cacgggtaca gtttttggcc agaaaagttc agtatatttg gttatacgta
    33841 cttgttcgac cagatgcagg ataaaatttt ccaagcgctt ttcgtcactg tacttgttac
    33901 tgttttaggt acactgatca atagcacggc tacttcttta tatgcttatg cgatttcacg
    33961 gtcaaacttt ccattccgtc gtttttttac cgttttttgt ttgattacga tgttgttctc
    34021 accagggatg gtggccaatt atcttgttat gacaaatctt cttcagttaa aagatacgat
    34081 ttgggcattg atcttgccaa tggctgtcag tcccttcaat attattgtga tgcgcacatt
    34141 ctttaaacgt tcggtctctg attcgattat tgaatcggca cggatcgatg gagctagcga
    34201 actgcgaata tttgttcaga tcgttttacc gttagctgtt ccaggtattg cgacaatcag
    34261 tttatttgcc gcattgggtt actggaatga ctggttcaat gctttactat acatccaaga
    34321 tgataagcta gttccactac agtatctttt gatgaaaatc caaagtaata ttcaatatct
    34381 gacacaaaat tcaggagcag gaagccaatt gacaggcgga ttagcctcag ttccaggaga
    34441 atctgccaga atggcgatcg tagtcatctc gacgttgcct attgcgatca gctatccatt
    34501 tttccagaag cattttgtca aaggtctaac aatcggcgga gtaaaagaat aaagaaacaa
    34561 aaatataaat cataaaatta ggaggaagaa aaatgaagtt atggaagaaa ctagccttta
    34621 caggtgtttc agcgttgttg ttgggaacat tagcagcatg cggaggttct ggttctaaag
    34681 accaggcaga agctagcaat tcggacactt tgcagatgta tcaaatcgga gataaaccag
    34741 ataatttcga tcaattgatg gaagtagcaa acaaacgaat cgaaaaagag atcggtgtaa
    34801 aagtcaatat caattacatt ggctggggcg attacgaaaa gaaaatgaac gtcatcattt
    34861 cttccgggga aaattatgat atcgcctttg cgaacaacta tgtttccaat gcccaaaaag
    34921 gagcctttgc tgatttgact gaattagcgc ctaagtacgc tgaaaaagct tataatgatt
    34981 tagatgaagc atatattaaa ggaaatctgg tcaatggaaa attatatgct ttcccagtca
    35041 atggaaatgt ctttgctcaa caagtactta cttttaacaa agctttacta gataaatacg
    35101 atctttcaat tgatggaatc caatcttacg ctgatgcaga aaaagtcttg aaggaattcc
    35161 atgaaaaaga accaaacacg gcagcttttg ccattggaca aggcttcaaa gtccaaggga
    35221 actttgatta tcctttaggg aatacgttac catttgctat tgatctggat ggagatgatt
    35281 cgaaaatcat caaccaatac gataatgaaa cgtatatcgg actgttacgt acaatgcata
    35341 gctggtacaa acaaggactc attccaagtg acgctgcaac gagcaataag gattatccac
    35401 tagaaggaaa tacttggcta atgcgtggag aaacacaagg accgtatgat tatggcgata
    35461 caattttgac aaatgcagca aaacaagaac ttgtctcaaa agcaattact gttccactaa
    35521 aatctacagc tcaagcacaa atggcaaatt ttgtcgtatc aaatacttca aaaaataaag
    35581 aaaaatcagt agaacttcta gggctgctta acagtgatcc agaattattg aatgggcttg
    35641 tttgggggat cgagggagaa gcatgggaaa aagtcgatgg ttcagatgat aaaatcaaat
    35701 tgctagatgg ttatcagcca aatacacata tgtctgcttg gaatacagga aacaacaaga
    35761 ttctatatac acaagagtct attacggatg acatgattgc caaacgtgat caatcgattg
    35821 ctgatgcaga aacttcaccg attttaggat tcagcttcaa cactgacagt gtcaaaacag
    35881 aattaagtaa tatttctaat gtcatgaatc aatatttaga tggattgaat acagggactg
    35941 ttgatccaga tgaaacatta ccgaaattga aagacgcttt ggacaaggct ggctatgata
    36001 aggtattgaa agaaatgcaa aaacaatatg atgagttccg acaagaataa taatgaataa
    36061 agacaaaggg gttgtgacaa aagacgtgtc acaacctctt gttccgaata aacggtgttc
    36121 aaaagccagt ttctcggtat taagctaaat atatgtaaaa atgtggaaag ccatattcac
    36181 aaaatttttc ttactactcg aaactaagcg gctatttcac aaactcttgg taaacggtgt
    36241 tcaatcagct aaccctcggt attcgctcac aaaacgacaa aatatgagga actatttttc
    36301 cgtttgtttc tctaataatc aggtcaaggt gctgattgcc caaccttttt ttgtataatg
    36361 agaaagtata aacttaatgt ttggaggaga agatatgtta gggaaggttt tggaagagtt
    36421 atttatccgg atctgggtca ttataaaact aaccttgtat ttctggatat atacatttgc
    36481 cggcgggatc atctttggat taggtgcggc atggaaaaca gtcaatgaac tattttattt
    36541 gtacggattc gagtataaag aaatcacaat aaaaagaggc tggaatatat ataaaagaaa
    36601 ttttttaaga ggcaatctgc tatttagttt atttttatct ggtactgctt tattgagtta
    36661 caatttatat ttatctgttc aaatcaaagg gctcattttt ttagctattg attttatttt
    36721 actttttgcc ttgctctgcc tatttgctac ttatcaatac agtatgattt tagatagtga
    36781 atatacgatc tctgttccta atctgctaaa gctaagtttt atttcggttt tttccagctt
    36841 ttcgtctttt ctaaaaataa ttattggtag cggtataatt ttaggcgtga cttggcaatt
    36901 caaaggattg atcctgtttg gtgtcattgg tcttttgacg gtttggaatg gtacgatgac
    36961 aacacattgg cgtgaagaat tagataaaca gttggaaagt tatgaataag tttcggattc
    37021 tattttcaaa aggaacctta ctaaatcgtc tgttgcggaa atacgcggtt atcatgatcg
    37081 gtgtaacgat gactgctacc gttattttta gtatccatac ttgggaacaa aatcaaaaac
    37141 aggcagaaaa catgacaagt gatgccgttc aaagcacaag cagaatgctg aatgataaaa
    37201 caaccttgag taggatcatc aaaaaccagc ttgtagggaa ttccgaaaag atcgaaaatg
    37261 tgacgaccta cttaacaaaa cccatagatc agtatctgat gtatgtatac gaacagcaaa
    37321 acagtaccga tgaattagtt tctttcccaa atcaaatcaa agatctctac gcaaattatg
    37381 aagaactaag tgcgatatat atcgtgttga atcaactacc ggagtattat gaatcttcta
    37441 gagaaaacaa aggtggggaa ataaaaaagg ggacaccaaa attactagac gccttttata
    37501 tcaagttgcc tatcacacaa ggaggagctg agtcaggaag tatttttatt ggttttcaaa
    37561 agaaagaact agatatgatt ttagaaaatc taacgtcatt caatggactc tctttataca
    37621 tgatttctgg aacgacaaat cgactataca cattccatga taataaaata gctaaagaaa
    37681 cgtttgaaag acaagaaatg atcatcacag agagtctgaa gaaaaattca caattgccga
    37741 ttgacgatct ggaaaaaaac aattttgttc aacaccaaga actgtctgat gattatcgta
    37801 tattagctgt actagataaa aaaagtgtaa aaatcgaaac gggaaaaaat cttgccccgc
    37861 tgatcattgg tatcattatt ttagacaata tactgcttat ctttctttat aaaacattca
    37921 aacgatattc acagcaagta tctatcgtca tgcaggccat ggatcaaaca gcagcaggga
    37981 atttagagac gcggatcgac ataacaaaca cggaatatga actgaaggaa ctttcaatcg
    38041 gtatcaacga aatgttggat agcatcaatc agtttgtaga agacatctac aaattagaaa
    38101 tcaaacagca agacgcacat atgcgggcgc ttcaagcaca gatcaatcca cactttttat
    38161 ataatacatt agaatatatc cgaatgtatg caatcagcga aggaagtgaa gaattagcag
    38221 atgttgtgta tgcgttttcc gctttgcttc gaaacaatac gaatcaagag aaaacgatca
    38281 ctttaaaaga agaactggac ttttgcgaaa aatatgtcta tttgtatcaa atgcgttatc
    38341 ctaatcgagt agcctatcat tttatgatcg atcctgattt ggaaaagatc gaagtaccta
    38401 aatttgtgat ccagccatta gttgaaaatt attttaaaca cggtattgat tttactcgat
    38461 tcgataatgc gctaagtgtc aaagtcttgc aggaaggcaa acgggtaagg atcatcatca
    38521 aagataatgg aaaagggatg actgaaaaac ggctaaaaca gattgaagaa aaactgtctc
    38581 atcctaaagt ggaacttcac ggttctatcg gtctgcaaaa cgtgaatgaa cgtttacgtg
    38641 ccagcttcgg cagcagttat tatatgtcgc ttgagaataa tgagacaggt ggactgaccg
    38701 tttctattac attcaaggag ggatgagcgt gtatcaagtg ttattggtag ataatgaata
    38761 catgattttg aatgggttaa aaaagataat tgattggcaa agtttaggct ttcaaatagt
    38821 agcaacagca gagaatgcca aagaaggact agctgtactt gaacagcgac agattgattt
    38881 agtagtaacg gatgtgacaa tgccagaaat aaatggactg gaatttattg aagcggctca
    38941 aaaagaacgt cataattttg aatttatgat tttatcagga taccaagaat tcgattattt
    39001 gaaaggaggt atgcaattag gcgccgtgaa ttatttgatg aaacccgtga ataagttcga
    39061 attggttgaa agcctcaaga aaatcaaaac acggttagat cagcaaaatg aacaaaaaaa
    39121 tcaacaagaa atctatcaag aactgttatt cagtcaatgg ttgaatgaag aattggatga
    39181 aataagtgaa gaagaaataa taggacaaat aagtgagaag cagcatagga tagtattgat
    39241 tcaactggca agaactcatg atactcttat caatagatgg ttgcaagaac ggcaacaaat
    39301 cttttactat caacgaaatt acggagaccg tgtattgatc acgttgttgt tggaggcaga
    39361 tgaagttgat ggcttctgtt gttttgttca agaaaacttt cctgatcagg aatggctgat
    39421 cagtatcggg gaagagacag attctttgga caaaatccct gaaacattcc aacaagcgaa
    39481 agacaatcta cagttgcatc aattttatgg agataaagac gagcatgttt tttacgcagt
    39541 acaagcagaa acaaaagatc aaaccatcga tttttcaagt ttcagacgcg tgctgcaaaa
    39601 taaacaattg gaagtcgctc aaaaaatgat cactgatttt tttgaacagt ttcagttagc
    39661 agccatgatg ccggaagata tacgatattc cagtttttta ctgtttatgg agattcaacg
    39721 ggaattgatt gatctggaag atgaggaata tttacaagga atcgaaaaaa tccatcaggc
    39781 aaaaacggtg caagaacttc agcagctact tctgtcattc atcaaaaagc atcagagaca
    39841 gaaaaagtac agtgacaatg tggaaaaagt aatcgtaatc ctgcaccagc attatcaaga
    39901 accacttaca ctcaaagaag tgtcagaaaa cctgcattta aatgtcatgt atctaggaca
    39961 gctgttcaaa aaagaaacga aaaaaagttt ttcagcttat ttgaaccatt tacgtatgga
    40021 aaaagcgaaa caactgcttt tgcacagtaa tcaaaacatc aatgagatag caagtgagat
    40081 tggctacaac aacaccacgt atttctctaa attattcaag aaaatcgtcg gcagatcccc
    40141 taaagagtac cgagaaaaca gtggagaatc ataaaagaaa aagccaatgt aatgaaataa
    40201 cttataaaaa attgtctaga aatctaattt tgggctgttc ttattacttg aggcaaggca
    40261 gctttttcat gacctctcga taaacggagt tcaaaagcca gtttctcggt attaagccaa
    40321 atttatgcaa aaatgtggaa agccattttc acaaaatttt tcttaatact cgaaactaaa
    40381 cagctttttc acgacctctc cactaaacgg tgttcaatca gctgaccctc ggtattagct
    40441 caaaaaatgg caaaatatga ggaactattt tgccatttgt ctctctaata ctcaggtcag
    40501 aacgctgatt tcacaacctc tcaataaacg gtgttcaaaa gcttgcatct gcggtaataa
    40561 gaccaaccaa acgaaaaata tgaggatcta tttttgcttg gctgttctta ttacttgatg
    40621 caggacagct ttttcacaac ctcttgttaa ttatagtttg ataaggaaaa aggcaaatct
    40681 tttgcttgat atttcttagg gtgagggatg atccctaatt ggtaagagat cgtgccgcct
    40741 ttcagcaaat cttgatgggt aaaatataat ttcgtatatt ctttgtccat ccgtttgatt
    40801 ttatggataa attgttgctg cggccgatta ggcgttgctt caatcgtcaa ttcctttcca
    40861 tttgacaaaa gcaaaacagc cttgtcaatt aatggcatac cgataacata ttcaccggtt
    40921 ccaggcgtga caggataaaa tcccagacta ttgaagatat accaagcggc catacttcca
    40981 ttgtcctcat ctccagggta acccattgga gaatcgtcga aggtctgagt catcaactgt
    41041 ttaagcagtg gctgtgccat ttcaggttgt cctatataac tgaacaagta aggatagtga
    41101 aaacttggct ggtttgaaat agctaattgt ccaaattcta tcgcggccat ctcactcatt
    41161 tcgtggatct caaaaccata tcctcctggg tcaaacgttg ggggctgatt gcacagctca
    41221 atgagttttt ctttatatct ctcactgcca ccatattttc cgatcagtcc tgaaaaatcg
    41281 tgataaacag caaagctgct ttgccaagca cttccttctg cataatcttg tccccaacga
    41341 ttagctgaaa atggttctct gaacttgcca tctttatctt ttgaacgcat aaatcctgac
    41401 tcatagtcaa agatattttg atagttcaat gattgctgct gatatttctt cgtcatttcc
    41461 tcttcttcta gtaccttggc aacttggcta atacaaaaat cgctataagc atagtctaat
    41521 gtgtgattga ctgattcgtg gtagtgatta ggaacatagc catatgtcaa gtaatcttct
    41581 gttccttggc gtccataatt tggatgtttg ctttgaaccg tagcaccttt ttccattgcc
    41641 gttagaaatt caggcatcaa gtctcgtcgg atatctttta cagcagcatc tgcaatgacc
    41701 gcatcgatca atgtcccagg cataagtcca cgttcatcag gagacagcca ttttggcaaa
    41761 tagccacttt ctctatagct gttcaaaaaa ccttccagca tttcttcgta tttttctaca
    41821 gcaatcaaag aataaagagg ataaaccgtt ttatacgtat cccaaaaccc attatttgta
    41881 tagagaacac caggttttat agatcgacta gtcgtatcat agtggatttt ttgcccacta
    41941 ggatcaattt cataaaatgt ttgtggaaat aaaaacaccc gatataaatt atgataaaac
    42001 gtccgcaatt gttgttgatc atggtgtgtg agctgtatac gatcaaaata ggactgccat
    42061 tgttcttgac tgtgagcaag gtaagtctct ttgctttggt tttgttctag ttccaggtta
    42121 taagctgctt gttccgagct gataaaagat gtcccaaatc ggatagtttg tttttttgtc
    42181 tgttcaaaat acaacgggat cgagtcgcta tttttgttgg aaacagctaa ctcatcaatt
    42241 gttaaaggat attcaaatct caatataaaa taaaaagaaa aatcaggatc ttctgaacca
    42301 gcaaaatgtg tgatttttcc ttccactgtg taaggatcta taacaaagag ctgatggcgt
    42361 cccggaaagg ataaaagtaa accgctgtca tttttgctgt aatcaataga taagattccg
    42421 ccatacatgc taggtatcaa tgtagaacag atgccataac gtaattgaca gatcgacaga
    42481 tgagtcgggc aaaatatact ttcttctggg cggtaagaac tttgagcatg gaaaagggtg
    42541 ttctcctgta gttttccatt gatcggcgta aacagcatat gactgaaatc acccatccaa
    42601 ggacttggtt gatgggtaag acggtagcct tgaaaaacgc ggtcatcagg atgaaaccac
    42661 cagctgccgt tttgatccgt agtttgcggt gcaaaataat tcatcccaaa aggaacgcca
    42721 gtataaggct ggcagttccc attagagaaa tttggctgat tcgctgttgc atgtctagta
    42781 tctatttgac cgatattcat tttatttctc ctttgttgat tgtcttttga tgaatgaaac
    42841 tggaaattta ctatcggatg gtcgatcttt tgtctctaac caagtgacca aagcatctcc
    42901 cgcaagctta cctaactgtt caaaatcttg tgcgatggtt gtcagtggcg ggtcaacaag
    42961 agctgctgct tggatatcat caaatccgat aattgaaaaa tcttcaggga tatgataacc
    43021 atgctgtctc aagagattca tggtctggat agcgacaaca tcgttttcac aaacaaaagc
    43081 agttacttca tacttagtga tataagaaag caattcatct aatgtcgcgc ttttgtcatc
    43141 cagtgaagtg tggaaagtca aaccagcttt gtccaatgct tcaaggtaac caaggtaacg
    43201 ctgtcgaacg gattgtggat gagtctgcgt accaaacaaa taagcgattt ttgaatgtcc
    43261 ctgttcgatc aaataagagg cagcaagcgc accgccttgg aaattatcgg aaagaacggt
    43321 aggaaaaggt aactcataga tttttttatc taatatgacg acagggaatt ctttcaatga
    43381 aagctcaaaa agtaagtcaa gatgttgttc tgtatcaaga gcataataaa tcaatccgtc
    43441 aaattcattg attagctctt ttgctgtttt attttgtaga aagtcaagcg tcgtcatcat
    43501 gacatcaatc tgtttatctt gcatcacagg gttcaatccc ttgctaaaat caccaacaga
    43561 caaatcagcg acatatggaa gaagaaacag aatccgtcgt gtttttgtag gagaagcaag
    43621 aatctgttcc ggagaagcgg atttaacgaa actgcctttc ccgcgaacgc gataaataag
    43681 tcctaattgc tctaattcag tcaatgcacg tttggaagtg attctgctta ctttataggt
    43741 acgtgaaagt tctttttcag ttggtagttg gctgtctaca ggtaattcac cagttaaaat
    43801 agccgtttgc aaatcattaa atattgtctg gtacaatggt tgattcatat aaacacctct
    43861 taatgatata tcatattcaa ataataccat aatggatgaa aaagtaaata aaaagatatt
    43921 ttttgaaagc gtagacataa ttggctgtat gaagtataat ctttaaagat atatcaaata
    43981 gaaagaaggt tttattagtg gcttataaag atataccaaa atcggtgcag aaatttatgg
    44041 aagatatcac acaaaaatgt ggggatatcc atgcggactg ggcaaagaat tttacagcag
    44101 catttgccaa tactctgttg acaacagtca aaaagcaaaa tgacggaacc acctttttat
    44161 tgacgggaga cattccagcg atgtggttaa gagactctac tgcacaagtt cgtccttatt
    44221 tagtgattgc aaaagaagat gaggaattag ctgacatgat cagcgggtta gtcaaaaagc
    44281 aattttttta tatcaatatc gatccatatg cgaatgcctt caacgaagaa gctaacggtg
    44341 ctggccacca aacagatcat acaaaaatga acgattggat ctgggaaaga aaatatgaaa
    44401 ttgattcttt atgctaccca atacagttgg cctatcttct ttacaaaaat acaggaaaaa
    44461 ctgatcaatt caatcaatct tttattgaag gtatcaaaaa aatcttggac gtgttcaaaa
    44521 cagagcaaga tcatgaacac tctccttata catttgtacg agacacgaca agaaaagaag
    44581 atacgctgat caatgacggg cgaggtgcaa aaacagcttt tacaggaatg acatggtctg
    44641 gtttccgtcc tagcgatgat acttgccgtt atggatatct ggtaccatcc aatatgtttg
    44701 cggtggtcgt gttaggttat gtggaagaaa tttttcaaac gatactcgat gataaagaaa
    44761 ttgtacagca aacacagaaa ttgaagaaag agatccaaga ggggattcag aatcacggac
    44821 gaacggttaa tcaaaaaggg caaacgattt atgcatatga agtagatgga atgggaaacg
    44881 ccacagtcat ggatgacagt aatgtgccca atctgatcgc cgcaccttac ttgggatatt
    44941 gttctgaaca agaggaagat tatctgcaaa caagaagaac attgttgagt aaagaaaatc
    45001 catatttcta tgaaggaaag tacgcaaaag gaattggatc ctcccatacg ccagaaaaat
    45061 acgtttggcc gattgcatta gctatggaag gaatgacaac gtcagacaaa tctgaaaaag
    45121 agcggatatt gaatttactt gtagcaactg acgcaggaac acaccttatg cacgaaggat
    45181 tcgatgtgaa caatcctgaa aattatacga gagaatggtt ttcttgggca aatatgatgt
    45241 tttgcgaatt agtcatggat tactttgata ttagagtaga aaagtaggag gtatcgtaaa
    45301 tgaaaaagaa agtatatatc atttctcata gccactggga tcgtgaatgg tacatggctt
    45361 acgaacagca tcacatgcga ctgattgaat tgatagacga tctactagag ctatttgaag
    45421 ttgatccgtc cttcaacagt tttcatttgg atgggcaaac gattatttta gatgactatc
    45481 ttcaagtaag gccagaaaaa agacaggcaa tccaacaagc aatcaatgaa ggaaaattga
    45541 gaattggacc attttatatc ttgcaagatg attttcttat cagctcggaa tcgaacgtga
    45601 gaaatatgct gattggcatg gaagaaagcc gtaaatgggg aacccctgtc atgttaggct
    45661 attttcccga tacatttgga aatatgggac agacgcctca attaatgaaa caagctggta
    45721 tttcagcagc agcgtttggc cgtggtgtaa aaccaattgg ctttgataat caagttttgg
    45781 aagcagaaaa ctattcttcc caatactcag agatgtggtg gaaaggacct gatcaaacag
    45841 caatctttgg tctgctattt gccaattggt atagcaacgg gaatgagatt ccagtagaaa
    45901 aagaagcagc tcttgccttt tggaagcaaa aattagcgga tgcagaacaa tatgcctcta
    45961 cgaaccactt attgatgatg aatggtgttg atcatcaacc ggtacaaaaa gatatatcaa
    46021 aagcaatcca tctcgcaaat gaactgtttc cagattacga gtttattcat tctaatttta
    46081 ctgactatct ggaagcagtt caaaaagatg tgccagaaga cttaggctca gtagaaggag
    46141 aattgacaag tcaagaaacg gatggctggt atactttagc caatacagca tctgctcggg
    46201 tttacttaaa acaatggaat accaaggtcc agcgacagct agaaaatatt acagaaccac
    46261 ttgcgacgat ggcttatgaa gttagtggaa actatcccca tgatcaatta gattatgctt
    46321 ggaagacatt aatgcaaaat catcctcacg acagtatttg cggttgttca gtcgattctg
    46381 tccatcggga aatgatacct cgttttgaaa aagcagatga agttggaaag tatcttgcac
    46441 aagattcctt agaacagctg accgcagcaa tcgatacgac cggattccca aaagacagct
    46501 ttccatttgt cattgtaaat actgcaggaa tggataaaac tggtgaagca gaaataacca
    46561 tcgaattaga aagaaaaaga ttcgctgaag gaatacctga acaactatat caagagttag
    46621 aaaatttgcc taaacgtaag tatcatgtag aaacaaaaag tggggccact ataccagcta
    46681 ttttatctga agaaactgtc caatttggtt atgatttgcc gaaagaccgt ttccgtgtgc
    46741 catatatggc aagaatgatc aaagtgactt taccattaga aaacatgcca gcattttctt
    46801 gggaaacatt cgcgcttgta gaaggggaag cgaaagcaga agaaaaggaa acaatgattc
    46861 atcagagtgg acgaatcatc gaaaacggcc ctctacattt gacgattgaa aaaaatggta
    46921 ccattacaat ggaagatcgc aaaaacaaac gaaagttgaa taatctgcat atttttgaag
    46981 atatcggcga tataggaaat gagtatatct ttaaacaacc tttctgtgat cagccaatcc
    47041 tatccagtaa caaagaaaac tctgaagtaa aagtattagt agatacaccg gaaatagcaa
    47101 aaataagtat tctacaggaa atggaaatcc ctgtttctgc agacgagcgt ttagaaaaag
    47161 aacagcagat ggttgtggaa tttcgttatc gaaaagcaga acgatccaaa gaaaaacgaa
    47221 tccttcaaat aaaaacaatc atgacaatca gaaaagatag taaaaaaatc gactttgaaa
    47281 cgactctcga caatcagatg aaagatcatc gcttacgtgt cttgtttcct acaaagttac
    47341 atgtggaaca tcacgaagca gatagtattt ttgaagtggt gaagcgccca aaccatgtgt
    47401 ctaaaagttg ggaaaacccc acgaatccgc aacatcagca agcatttgtc aatattcatg
    47461 atgaagagta cggtgtaaca gtcggaaact ttggtttgaa tgaatatgaa gtaacagaag
    47521 acggacaaat cgcagtgacg ctacttcgca gtgtgggaga actaggcgat tggggatatt
    47581 ttccaacacc agaagcacag tgtctaggtg agcatcggtt caattacagc attgaactac
    47641 atggaccaga agaaaaattc tctacttatt tgcatgcata cgcagcacag attccttttt
    47701 ccactcaaca aatcaaacat catgaaggaa cattgatttc aaaacaacaa tatttaacga
    47761 taaaaagtga aacgtttgca attacagctt tgaaacgcag caagtttagt gataaagtag
    47821 tagtaagagg tttcaatatg tctagtcatt tagaaaaatt ggaaataact aaagacaatg
    47881 gaaaaactgt catattgaat ctgcttgaag aaccaacgaa gcaagcggtt gtcccaataa
    47941 tccaacctta tgagattcgg acaatcggat tcgaggagga aaacgaatgt atggcggaat
    48001 agaagcaggc ggaacaaaat ttgtgtgtgc ggtttcagat ggtggagaaa ttttagaaaa
    48061 attaagtatc cctaccacaa caccagaaga aacattggat caggtatttg aattttttga
    48121 tcgttatgaa ttgaagggaa tcgggattgg ctcattcggc ccgattggta tcgacaaaac
    48181 aaaagataat tacggatacg ttttggcaac tcccaaaaaa gggtgggcac aattcgattt
    48241 tcttggcaca atcaaggaac gctacaatat tcctgctgct tggacaacgg atgtcaatgc
    48301 tgctgcatat ggggaattga agcaaggagc agcacaagga aaaaatagtt gtatttacct
    48361 taccgtggga acaggaatcg gtgcaggtgt cgtgatcaat gaagaaattt tttcagggat
    48421 cgcacatcct gaaatgggac atatttgggt gaaacgccat ccagatgacc attatgaagg
    48481 tacttgtcct tatcataaag attgtttaga aggattagca gcaggaccgt ctattgaggc
    48541 acgcacaggg atcaaagggc aagatctgcc gcaagatcat cctgtttggg ctattcaggc
    48601 ttattatatt gctcaagcac tgatcaacta tacgttgacg ttagcacctg aaaagattat
    48661 tttaggcggt ggggtaatga atcaggatca tctccttcaa aaaatccgtc agcaatttgt
    48721 tgaattgatg ggtggttata tggaaacacc tcaagtaagt gaatatatcg ttcgttgggg
    48781 actgccgaat gaaagtggga ttatcggtag tttgctgtta gcagaacacg aacatcaaaa
    48841 gtaagcagac aaattacaca aaaagaacag agtcttatca ttatctgctg ataagactct
    48901 gttctttttt atttctattc ccataatcca ggtaaagctt taccgactat tttttcttga
    48961 gtaaatggat ggatcatgtg cagttctaat gcatggagca tcagtcgttc agctgttcta
    49021 ttttggtaga gagggtctcc aacgatcgga tgtcccttat gagctaaatg aactctgatc
    49081 tggtgtgtac gtccggtttc caaaacacaa tagacttgtg tttgttcaga aagtactttg
    49141 ttgacagtga catgtgtcaa ggcgctctga ccatttttat catctacgac cctttttctc
    49201 cgatcatggc gatctcgtcc aattttattg gtgatggtca tatctttggc aatttctccc
    49261 catacgatgg cttgatatct ccgatagatc attttttgtt ccaacattct tccaagtatc
    49321 ggcaagacaa atggattttt tgcaaataaa acggcaccgc ttgtttcttt gtccaagcgg
    49381 tggacaacgt aaggtcgttg ctgtttagtg tcgagataag cagctaaatg attgagtaag
    49441 gtactgtttt ctgtcggttc atttggatga gtcttcattc ctgcaggctt atccactata
    49501 atcaaatgct catcttcata taaaacacgg atgtgcttcg catctcctaa ttgaacttct
    49561 tgataattat aatctgtttc ttcgaataac aatgtgatct ggtcattgcc ctttacttca
    49621 tgatggaaca aagcaggttg ttgattgatc caaacgtttt tacgtatacg caaaaagtgt
    49681 cgaacctttc taggaactaa ccattccttt tcaagcaagt cgcgaattgt tgtttcagga
    49741 tggttcatag gtaaagtgat cgtgattttc acaagtgtac tcctttcagt gcaatcgcag
    49801 actaattgta ccatttttaa aacatattta agaaaaaact tacatttttc tgttcattct
    49861 tatgttactc tacttgcact aacgtaaaaa aacatattga actacaactt aagcaggaag
    49921 aaaacactct ttcactatgg taaaataaga cgattgaatc aaatagacag gagaagaagc
    49981 aaatggattt tcaaagcatt ttagaaaaga taaaagctgc tttgatcagt ttttggcgtt
    50041 ggatcagacc atatctcgga caattccatc gatggcgaaa gcgcatctgg aaaaaatatc
    50101 atgtgaacaa attgattttg ctgattggtt tgatctgtgt cttagtgaca agtatctacc
    50161 tctttatttt agcaaaacaa gcaaatgtcg aaacgttaaa atcaggatta agccaatcga
    50221 cagtcattta tgataagaaa aacgaagaag ctggcacact gtacgcccaa aaaggaacat
    50281 atgtagaatt aaacgcgatt tctccctata tccaagatgc agtaatctcg acagaagata
    50341 ggaattttta cgagcatcac gggtttgata tcaaagggat tgcccgtgca gcagtccgaa
    50401 tggtcttgtc tggcggaaca tcagggggcg gaggaagtac gatcactcag cagcttgcca
    50461 aaaatgcgta tctgacatta gaccaaacgt ttgatcgaaa agcgaaggaa ttatttttgg
    50521 caatcgagat cgaaaagaag tacagcaaag aagaaatctt gaccatgtat cttaacaatg
    50581 cctattttgg caacggggta tggggtgtcc aagacgcttc cagaaagtat tttggagtag
    50641 atgcaacgaa tgttacgctg tctgaggctg ctactttggc aggaatgctg aaaggtcctg
    50701 gtatttataa tccgatcgat cacccaaaaa atgcgaatga tcggaaaaac acagtactaa
    50761 gtgtaatgga agaaaacgga aaaatcacaa aagaacaaga acaagcagaa agccagacag
    50821 atatcagcgc gtatcttaat gacacatacg ataattcaga ttctggttat cgttatcctt
    50881 attattttga tgcagtgatc gatgaagcag ttaacgagta tggtcttgat gaagaagatg
    50941 tcatgaataa aggctataaa atctatacag ctttagatca ggattatcaa aagcaattag
    51001 aagctactta tcaaaacagt gcattattcc cagcaaatgc ttcagatggt gccatggtcc
    51061 aatctgcttc agtagcttta gatccgaata caggtggtgt acaagcacta gtaggacgaa
    51121 gaggagatca tgtctttaga ggattcagct ttgctacaca gatgcgtcgt tcaccaggat
    51181 caacgatcaa accattaagc gtatatacac cagcactgga agctggatac aagccttcca
    51241 gtatcttgaa agacgaaccg caaagttatt acgatgcgca taattttgac gggacatacc
    51301 aaggagaagt accgatgtat caagctgttg cacaaagttt gaatttgcct actgtatggc
    51361 ttttgcatga gatcggttta caaaaaggat atgataaagc agaagaattc ggcctgcctt
    51421 tagcaaaatc tgataagtat tatggcttag cccttggtgg actggaaaaa ggagtatctc
    51481 cattgatcat ggcgggtgct tacagtgcat ttgccaatga tggtcagatg tatacgccgc
    51541 atcttatcac gaaaatcgtt gattcgactg gagcggtgat cgtcgataac acaaacaaaa
    51601 aaccaaaaca ggtcatatca aaggaaacag ccgatgaaat gaccagcatg cttcttggta
    51661 cattttcaaa tggaacagcg gctgctgcga atcctgcagg ttatacgata gcagggaaaa
    51721 caggaaccac agaaactaat ttcgatgcca caaaagcaaa tgaccaatgg atgatcggtt
    51781 acacgccaga cgtagtgatt tcgacatgga tgggttacga agaatccagc aagctgcact
    51841 atttggaagg gacaagtgga aatgttgtcg ggaaagtctt caaatcagcg gcagaaggca
    51901 tccttccgta tacttcaaaa acaggattta gtgtagcaga tgcctatgcc acaggaggac
    51961 aagtggtagc tgcagatcaa gttggaaaca caggaaattc taatggagag tctggaaatt
    52021 ggcaagataa cttgaatcaa tatggtgaac aagcaaaaga agggctgaaa aacttcggcg
    52081 atatggtgaa agaaggcgtt cagggaattg gtgaagcggc taaagacctc tggcggaaat
    52141 atcaaggaga gtagcccctt tgaaaacgaa taaccccatg ttacaataga gagtaactac
    52201 taaaagaaaa gagggcataa catgtcaaac atctacgata gcgcgaatca aatcgaacgt
    52261 gagatccgtg aattaccaga attcaaagcg ttgaaagaag cgtacgagaa agtacaagca
    52321 aacgaagaag cacacaaact gttcaaagac ttccaagcga tgcaaatcga attacaagaa
    52381 aaacaaatga gtggacaaga gttcagcgac gaagatgcaa tgaaagcaca agaaatggct
    52441 gtgaaaatcc aatcagaaga agtaatcaat gacttgatgc aaaaagagca aggcttcagt
    52501 acaatcatca atgacttgaa ccgtatcatc atgacaccag ttcgcgacct ttacagcgaa
    52561 taaaactatt ttatgaaaca acagagggtg tgaaagagac gttcggcctt gagcgatgac
    52621 aaaattgctt cttattgccg ataggctgtc tcttgaacac catttaccaa gaggtcgtga
    52681 gcctaccgtt taactctgag ttacaaggaa caatttcaaa aaacagcttc tcatgtttga
    52741 tgactattgt gacttgtgac cgaggagttg gcaggagaac accgtttatt cagaaatagg
    52801 agctacgaca aaagtcttgt catagctcct attttttgtc attcattttt caagcggtag
    52861 aaatagcctt tttgagctaa cagtttttcg taagtaccta tttcaacgat ttttccttca
    52921 tcgatcacaa cgattttatc tgcctctttg atcgttgaaa gccgatgagc cacaataaaa
    52981 gtagtgggtg tttctgtcag gtaattcagg gcttgctgga tttttttctc tgactggtta
    53041 tctaaagctg aggttgcttc atctagcaaa atgatttttg gctgacgtat caacgctcgt
    53101 gcaatggaga tacgttgctt ttggccacca gacagcttgt tgccatgttc gcctactaag
    53161 gtatccagac catcaggaag ctggtcaatc agtgaagaaa gttgcgcagc ttcgatgact
    53221 tcatctaaac gttcttttga tacgtttttc aagccataag tgatgttctc tttgatcgaa
    53281 gcggagaaca acaaagtggt ttgaggaaca acggctaaat aatttcgcac acttcgcata
    53341 tccagttcat ccaaaggctg atcatctaga aaaatttttc ctgaagtcgg ctggataaat
    53401 ccaatcaata agttaaggag tgtagatttt ccagagccag atggcccaac aaaagcaatt
    53461 gtttctccag ctttcacctc tagagaaaaa tgatcgataa tcggtttgag tgagtccgga
    53521 taaagaaaag aaacatcctc aaaacgaaaa tttccatcca aatgttggat ttttttctta
    53581 ccgtgataag tttctacatc gccagcaatc aacagttcgc caatagaagt gatagattcc
    53641 atgccttttg aaatcgtagg aatcagcgtg atcattccag aaacggaatt gacgatcgtc
    53701 gtgaaatacg tctgatacat cacgacatcg ccgggttgga tgcgcccttg taaagctaat
    53761 atcccagtga aaatcaaaca aatcagctga aatatctgaa aactagccca gctgactgat
    53821 ccgaaaacag attgcaggat atctaagtgg aatccttttt catagatttg agtaaaatgc
    53881 ttatttaagc gagttgtttc gtgtttttct aacccatgag ctcgagcaat cggtgctaat
    53941 tcgatcactt cgatcacttt tgcagaagtc tcttccattt cttgcctgaa gtctgagttg
    54001 gactgtctga tccttttacg gaaaaagaga gtaacgaatg cggcgagagg aacagtcaat
    54061 aagaaaaaca tgaaaacaac aggactttta taaagcgtga tacctaaagc tacgaataaa
    54121 ttgacagcga tatttaatcc gctgacaaat acttgagagg acaacgtttg gatagcttct
    54181 acatcacgga tgatctttga ctggattcgt ccagattgca attctttttg ataaggaata
    54241 gatagttctt ggattttctt gataagggtc gctcttagtc cagcttctac ttgacggatc
    54301 gaagtgctat ggtattttac atgaaaataa ttcgtcaata tattttgacc aatcagacaa
    54361 gccatcaaaa aagcgttgaa ataaatggcc tgcaactgag aagaatcttt cgatgaagct
    54421 gcattgatta cattggcaat agcgatcggc attaaccaag atggaagatg tttgataata
    54481 aaaaagagtc ctgacatggc aaaacgccaa taatttccct gataaagatg cagcaatgtc
    54541 tgaaaagcat ttgcatgata tttttgataa cttttctgta ttcgttcctc cataatcttc
    54601 tccttaacaa tcttggtaaa taaactgcaa gtgttctatt gcttcaggaa cataaatctc
    54661 aggagtagct tcaagagtgg cgtacattag aggacgctca tatttgatat aatgcagtac
    54721 cgggcggaaa tctaaacagc ccttgccaac aggtaccatg cggatctttc cattttccat
    54781 gatatagtct ttgagatgaa gcgctgtaat ataaccatgt aaattgtcca aggcacctcg
    54841 gatcactttt tcctgatcag catgattttc tttatgcatc aaattcgcac aatctaaaat
    54901 gatttttaaa tttggtgaag ctacttcatc gattaaacgt ttagctaact gatagttata
    54961 gattggatga ttgatccctg cttcaacagc aacagttacg ccaaaatttt ctgcatgagc
    55021 gactaattca atgatagaat ttctggcgat ctgataagct tcttcagtaa aattttcttt
    55081 tgtgtaaccg acagagacac taccggtttc cgtagcaatc atcttggctt gataggcaga
    55141 gcacagagca atttgctgtt tgaaagttgc caatgcttgt gcacgaactt cttgattttt
    55201 gctggatagg ttgatatagc atcctaaaat ggaaagttcg atattgtttt tttggaagta
    55261 ttcaccaaaa taggcagcac tcccaagtgt catgtcagtt aatttaagtt gttcaggaaa
    55321 tgctttttgt ggtgcaaatt ggatatggga caagtgaagc tgtgatactt tttgaacgat
    55381 ttcttcacga tttcgaacat ctaaatcgtg ggcacggatg cctaaattta atggaaacat
    55441 ctcaaactcc tttttgtaaa taattagcaa gaggcagacg ggattctttt atcaattcaa
    55501 caattattcg ggcaacttta tcagcgcctt ctggactaaa gtgggtattg tcttttagtc
    55561 cttctgggta atttttacaa gtatcaggta taagatgcag gtagaatttt tttgtctctt
    55621 cttttgagaa ggtctggaac aattcttgtg atcttgagaa cacatctaaa agaggaatat
    55681 ggtgtttctc agcaaatgca cgcatcgctt ttggatagtc tccaagtata tctggattca
    55741 atgttccgtt ttctaagtaa tctcgtcgcg tcacagatgt cagtaagacc atttggacgt
    55801 tcgctttttt tgcgcattca aaaaatatct gcagattttt taaatagcta ccgaagggaa
    55861 gcgtacctct ttcttcttgg attttctggt cgttatgtcc aaattgtaca aataagaaat
    55921 cattcggctg aaactgtgaa gctagacggg ctaaccttcc ttcctggata aatgatttgg
    55981 tgctgcgtcc attctttgct tggttattga tctggatctc gggtgaaaaa taagcagaga
    56041 ttttttctcc ccaacctgtc tcgggacgct tgttttcatc tttttctgcc gcagtagaat
    56101 caccggcaat atggatagta ggcatgttat ctcttctttc ataaaggttt ataggcaatg
    56161 aagcagaaca gcaagagaag aagacggagc aaatttggtc cgtcttcttc tctaaaacgt
    56221 ggataaacgg attccgttat ttcactatcc tgtttttgat tcgttactgt tactattaat
    56281 caattaggca aaaaagccaa agtaattttt agcatttgta taactaatcg cttgaactag
    56341 acttcctaaa agttgttcat cttcaggtgc ttctcctcgc atgaccattt cgcctaaaaa
    56401 ttcacaaaga acacgacgga aatattcatg tctagtgtag gacaggaaac ttcttgaatc
    56461 tgtcagcatg ccgacaaaat tccccaaagc actaccatca gcaaattgtg tcaattgatc
    56521 gcgcatacca gctcgagtat cgttgtacca ccatccagaa cctaactgca gttttccatt
    56581 ctgttctttt tggaaacagc ccatcaaagc taaaatcgca ggatagtcat tcggattcaa
    56641 tgaataaagg atcgtctttg gcaactgatc cgtttcttct gcacggttca ataatttttg
    56701 cagaggaata gtcaaagaaa gatcattcat tccatcatag ccggtatcgg gccctaattt
    56761 ttccaacatt tgtgtattac agttacgata agcatggatg tgcagctgca tcgtccaatt
    56821 atgagaatga tagaagtggg tcaaatgtat cagtgtttct gtacgataag catcgatttc
    56881 atctgaagat aatagtttgt tagctcgtgc tttttgaaaa atctcttcta atactgtttc
    56941 atccgcttct ttatagcgta agatgtctaa agcgtggtcg gaaacacgac atccatgttg
    57001 atggaagtat tctatccgct gccctaagac ttctatcagt tcttgatagg tggtgatcgt
    57061 ttggtcagct gcttcttcca gtagtgtgac ccatgcatta aatccttctt tttcaatatt
    57121 gagtgcttta tctggacgga atgaaggtag aaccttcaaa tctggttctt catgagcaag
    57181 caactgatga tagtgcaagt cgtctgcggg atcatctgtt gtacaaatca cttctacatt
    57241 cgattttttt gcgatttccc gacggcgaaa atcaggagct gccaaaattt catttgcttg
    57301 tgtccaaatt ttctctgcat tttcttcatt tatcaacaag tcaataccga agaaacgctt
    57361 caattcaaga tgtgaccaac tgtaaagcgg atttccgata atttttggta cggtttgaca
    57421 ccaagctaaa aatttttcaa aatcagaagc atttcctgtg attttttctt caggcacgcc
    57481 gcaagctcgc atcaagcgcc atttgtaatg atcgcctcct aaccaagctt ctgtcagatt
    57541 gctgaaattg ttgttttcgt aaatttcttt tggatctaag tgacagtgat aatcaataat
    57601 gggcatgttt tttgcgtagg aatggtaaag ctttttcgcc caatcgtctt ttaataaaaa
    57661 atcatcagat aaaaacataa atcttccttc tttcttttta tactgtttta tgaaaatcaa
    57721 agtgttactc cgtttttaaa aatggcaatt tctcgaacgt cattttgttc atttttcgtt
    57781 tcttctccac tagctacagc gatgattttt tgaacaaacg attctaagat tacttccatt
    57841 ggttgttcta ataagacgcc tgcattaaaa tccatccaat gacctttgcg ttcaaaaaga
    57901 gttgtattcg tagatacctt gaccgttggg acatatgagc caaacggagt ccctcttcct
    57961 gtggtaaaca agaccaactg gcaatcggat gaagcaagag cagaggcagc tacaagatca
    58021 ttcccgggag cttgcaataa actaagccct ggttttctga ttttttcgcc atattgtagc
    58081 acatcaacga caggagagct tcctgatttt tgcgtgcagc ctaaagactt atcttctaat
    58141 gtagtgatcc cacctgcttt attaccagga gatgggtttt cgtaaactgg ttccccgtaa
    58201 gacaagaaat actgtttgaa gtcattgatc aagtcaacga ttgagtcaaa aacttcttca
    58261 ttttccgctc gtgccatcaa tacttgttct gcgccaaaca tttctggcac ttctgttaag
    58321 atcgtgctgc ctccttgagc aatcaagtag tcagaaaatg caccaagtaa aggattagca
    58381 gttattcccg atagaccatc agaaccgccg catttcaaac cgacattcaa cttagagagc
    58441 gggactgata tgcgctggtc attttccgcc gctgttaaaa gctcttctaa tagagccaca
    58501 ccttgttcga tctcatcgta aacatcttga gccactagaa atttcactcg ttcttcatca
    58561 tattcaccta aaattttttt gaattcagga actgtattgt tctcacaacc taatccaaat
    58621 actaaaactc ctccggcatt gggatgattt actgcgtccg ctaaaatttc tcgagtattt
    58681 tgatgatctt ttccaagctg cgaacagcca taaggatgct ttaaaatcgt aatatggtca
    58741 aactgtccca gatctggatg tttttccttg aactgtttga cgatcagttc agcaatgcca
    58801 ttcacacacc caacggtagg tactaaaaac aaatcattac gaatccctac ttttccattt
    58861 tttcgcaagt aaccttgaaa tgttcggttc tcaaaaaggt aatgacttgg atggacatct
    58921 ttttcatatc gataatccaa ttcaccagaa agattggttt ttacattatg agtgtgcagc
    58981 cattgaccgg cagttacgtc tgtcgtcaca tgaccgattg gatagccata tttgatcacg
    59041 ttgtctccag ctttcaaatc acccaatgca atcttatgac cttgcgggat atcttcaaga
    59101 gtggtgatcg tttgctgatc aatcgtcagt tgtgtttgtt ttggaatagg ggttaatgcg
    59161 acgaccacac tgtctcgtcg atttaatttc attgttggtt gcagggtttc aagcatggac
    59221 catcgttcct ttcatttctt gtaatactga ccggacacct ttttgatcga tctttgcagc
    59281 tatttcttga actgtatctg tcacattcgg tatttgagac aaatcttctc cccaaagcgc
    59341 agcgttttgc aataatcgag gaatagctgt tccattatca gaccaagcat cagtaaattc
    59401 gcttatcgtc ttttcatcat catgtggctt tacttgatcg cctcgataca taagaagtag
    59461 cgcagctagt gaaacagtga ttaacggtgg tacctgattt tgttcttcga tatacttctt
    59521 gaacactgga agcagacggg tgctgaactt tgaaacacta tttaatgaaa tcgcttctaa
    59581 tttgtgatgg gcaaaaggat tcaagaaacg ttctttgatt tggtcagcat aaatggctaa
    59641 ttcatcttta ggtaaagaaa gcataggaat caattctaga ttgaataact gatcaacata
    59701 tgcggagaat aaaggatctt tcattacttc ttctacagtt tccaattccg ccaacaaagc
    59761 aagagggacc atcgctgtat gcggtccatt aagcaaatgc accttacgtt cacgataagg
    59821 agtcatatca tctgtgatga tgacattcaa gccagcctgt ttgaatggta gttgattctc
    59881 caattcttta ggcccttcga tcacccaaag catgaatggt tctgctttga ccatcaattg
    59941 atcttcatag ttatgccgtt gattgaaaac acctgcatct tcgcgaggat aacctgggac
    60001 gatgcgatca actaaactac aacagaaaac attttctttt tctaaccact caacaaaagc
    60061 aggttctaaa tcccattttt ctgcgtagcg taaaatgatt tcttttagac gttcgccgtt
    60121 tctgtcaatc agttcgcaag gaatgatggt aaagccagct ttgtttaatt tgaaacgtcg
    60181 gtataaaaag gctgtcagtt tgcccgggag gctctgtggg ggagtatctg ttaaattatc
    60241 agtctccacg aattggattc ctgcctctgt tgtattggag acgatatagg ccaagtcgtc
    60301 attttctgct agagatagat aagcatccca ttcatcataa ggattgatca tttgttctac
    60361 tacggtgata atctcggaag tatcaacgat ttcgccattg ctgagtcctt gtaaaatgac
    60421 cgtatataaa ttatcttgct ggttcatcat atttccaaga ccttgttcta aaggttgaat
    60481 gattgcaaca ttacctttaa acaattgttg gttattcagc tgctgaatct gccaatcaat
    60541 aaatccacgc ataaaattgc cttcaccaaa ctgaagaact tttacaggtg cttcgttttt
    60601 tttcactaat tcttttgtca gttttttcat ataaacttcc tttctgtgtt atgcacacgt
    60661 taacattttt atataaaatt acttgtagtt tacaagtaat tgatcgactc acgaaggatc
    60721 aacaaggtgg agagctcaat tttagattgt tcgatcgtcc tgccttcgat caaatctagt
    60781 aaaagctttg ttccttcttg acacatttct ttcaaaggct tacgtacggt ggtaagcggc
    60841 ggattgagat aggagacgac tggagaatca tcgaacccga tcagagaaat gttctgggga
    60901 acacggaggc cagctaaatg tacagctctc aatgcaccaa tcgctatgtc gtcgttgccg
    60961 caaaaaacca gagtaggcag gtcagaaagt gataataggt attccatgtt ttggaggccg
    61021 ctttctaagc tgtaatctcc tgttaaaaaa taggctggat tgacagggat gctcgctttt
    61081 tttagacttt tcaatacccc tttttcccgt tcttttgtcg aacgaaaatt tttctttccg
    61141 ccaatataag cgatcttcgt atgtccgcat ccaataccgt aatctactgc ctgcataaca
    61201 ccggccgcat catcggcagt gacgttgata accgctggat cattgatgtg acgattgaca
    61261 acaacgaaag gaaattcttt ttctttgaga tagtcgatga aaggctgatc atcatcactt
    61321 tgactcataa cgatcagtcc atcgtagcgt tgcaggttga tttctgttaa atcaacaaca
    61381 tcgatacttt caacagataa actgtaattt gtgtctaata ctgaatggat gcctgcaatg
    61441 gaatctgcta ggaaatttga tgaagttcct ttatgcaaac ttgagaaaaa tagtccgatt
    61501 agatattttt tttgattcac taaacctttt gcactatagt ttggcgaata attcatttcc
    61561 ttagctagtt gtcgtatttt ttgttttgtt tcatttttta ttaaactgct gttattcaaa
    61621 gcacgagaaa ctgtcgtatg agaaacgcca gctgctttag cgacatcttt gatcgttacc
    61681 attccatcat tttccttact ttttcacttt ttgttaacgc attcatcata ttacgataac
    61741 tacgataagt caatagatct ttgatatgaa aagattgcac acgttaaaaa ttacttggat
    61801 ttttattttt aattatgcta ttcttgaaag cggggaatgc tcatttaatt agatgagtat
    61861 caattttaca gaaaaatgaa agccttttat tttaaaagga ggagaggaag aaaatgaaga
    61921 aaagtacagt attttataaa atatttttac cgatgttttt attaggagcc gtacttgtca
    61981 taggatttag tttattcatt taccagaata cctatgaatc gatcgaatcg agttatttaa
    62041 cagacaaaaa gaatttgctc aggcaagtta aaactaacgt tgaatggaaa attagaacga
    62101 ttgaatattc gttttctacg tatggttcga ccaaaaattt ctcggacata ttcaagcatc
    62161 cgctgacata tacagattac tccacttatt ctgaaatcag gaaagaacta aattttatag
    62221 aaacgattgt tatggatgat aataattatg atttagtcag tttggctggt aaatggggag
    62281 taatcaatgg atcgttgagt caactgaccg aagaggaaat tgaaaagtat caacagaagt
    62341 acataaataa caaaaataat ttattttggc aaaagaaaaa caaaggaatc gaaatggtga
    62401 tttctttgcc aatgtttgaa aaagaaaaat atgcattggg aattgctacg atagagaaac
    62461 atacaataga acaagttgtt ggtgaaagtg gagaagacat actttctatt gaaaacgaag
    62521 ttggcaacct ttttactact cagacagtaa aaaataaaga gcaaccaact gtattaacgg
    62581 acgtggatct agattacaat cagctgaaag tgataagaga aaaagataaa acgtatatag
    62641 tactgaaatc agattataat aattggattt acagattaga agttgactct agtgcaattg
    62701 gcgcaatgat ccgcaatctg agaatcgggc tagttgcagt gtctttaaca ctggtaggac
    62761 tcattggtct tctttcctac ttattttcgg acagatttgc ccgtccgatt tctcaaatac
    62821 aggaacgtct gaatcttaaa tcaaaaggat tcagtgggaa agaactagat ttggtcgctc
    62881 aatcagtcag tcggatcata ggagaaaaag aagcgttaag tgcacactta gttacccaaa
    62941 agccacagct ggaaacgcta tttgtactta gtttatttag aaatcgagta gaaaggcgag
    63001 aactagatca gcggttgcag caatttggtt atagttctca aaatgactgc tattatacag
    63061 ctttggttca aatcgatctg ttagaagata gtcacggtgg ggagcgtgat ttgctacttt
    63121 tagcgatcaa caacatgatc acggaaattg tgccaaagga aaatcgaatg ctgccgatcg
    63181 ttttgaatga agaaatgcaa gccactattt atcgaatgga taaagatgat gcagaagcaa
    63241 gcaaaaaagt catggagtat tgccgactca ttcaaaaacg tgtaaaagaa tacttgaatt
    63301 taactatcag tataggcatc agtaaccggt tcgaaacgct gaatgaaagc aagcaatcgg
    63361 ttgatcgggc aaaagaagcc ctgtattatc gtgtaaatac tggtccaagt tcaattattt
    63421 tttatcagga aatcgttcct gctgctcatg aaaaaacact tattagatat ccgatagaag
    63481 aacaaaatcg attgtttgaa gccattcgtt ctggaaatca ggaagtgaag aatttagtac
    63541 atgaattgat tgatgcattg tttgcacaaa ataaaaatcc tttgagtcgg gaagtagttt
    63601 cggtccgctt gatcaatgaa ctcgttcaat taggacagtt attgggagta gattcaaaaa
    63661 actttgataa catgaaacaa atttatgtaa aagcactgaa caattatcat cccaaagaac
    63721 tagaaaaact tgttttagaa caattagttc tgccaatcac agaatgctct caagcaatca
    63781 ctgatcatga atttaaaaat ttgtcggaga atattatgca tatcgtctac acagaatatg
    63841 atcgtgatct gtctttagat gtgatcgctg ataggttgca ttataaccct aactatttaa
    63901 gtaatgtatt taaaaaggaa acaggagaaa aatttggtga ttttgttcaa aatcatcgtt
    63961 tagaggtagc aaaaaaatgg ttgaaagaga ctaacctctc cgtaaaagag attgcagaaa
    64021 gattgcaata tcgaaatccg caaaatttta ttcgtttctt taaaaagaag gaatcgatta
    64081 cgccgggaga atatcgaaaa aaatatttgt gaatcaagag gctgtttttc ttgtggactg
    64141 attcaagcaa taaaagaagt tagaataacc ctagtatttg tatttatgga tagttaa
//
LOCUS       DAPBBR010000009        63537 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPBBR010000009 DAPBBR010000000
VERSION     DAPBBR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 63537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.009"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(186..311)
                     /locus_tag="RD488_000581"
     CDS             complement(186..311)
                     /locus_tag="RD488_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7656680.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(445..1338)
                     /locus_tag="RD488_000582"
     CDS             complement(445..1338)
                     /locus_tag="RD488_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HDT7656681.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1520..2446)
                     /locus_tag="RD488_000583"
     CDS             complement(1520..2446)
                     /locus_tag="RD488_000583"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDT7656682.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2531..3292)
                     /gene="pflA"
                     /locus_tag="RD488_000584"
     CDS             complement(2531..3292)
                     /gene="pflA"
                     /locus_tag="RD488_000584"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDT7656683.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3536..5767)
                     /gene="pflB"
                     /locus_tag="RD488_000585"
     CDS             complement(3536..5767)
                     /gene="pflB"
                     /locus_tag="RD488_000585"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDT7656684.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6044..8494)
                     /gene="parC"
                     /locus_tag="RD488_000586"
     CDS             complement(6044..8494)
                     /gene="parC"
                     /locus_tag="RD488_000586"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDT7656685.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8506..10551)
                     /gene="parE"
                     /locus_tag="RD488_000587"
     CDS             complement(8506..10551)
                     /gene="parE"
                     /locus_tag="RD488_000587"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDT7656686.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10717..11151)
                     /locus_tag="RD488_000588"
     CDS             complement(10717..11151)
                     /locus_tag="RD488_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDT7656687.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11278..11916
                     /gene="plsY"
                     /locus_tag="RD488_000589"
     CDS             11278..11916
                     /gene="plsY"
                     /locus_tag="RD488_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDT7656688.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12048..12923)
                     /locus_tag="RD488_000590"
     CDS             complement(12048..12923)
                     /locus_tag="RD488_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDT7656689.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13005..13796)
                     /gene="codY"
                     /locus_tag="RD488_000591"
     CDS             complement(13005..13796)
                     /gene="codY"
                     /locus_tag="RD488_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDT7656690.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13814..15214)
                     /gene="hslU"
                     /locus_tag="RD488_000592"
     CDS             complement(13814..15214)
                     /gene="hslU"
                     /locus_tag="RD488_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDT7656691.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15228..15776)
                     /gene="hslV"
                     /locus_tag="RD488_000593"
     CDS             complement(15228..15776)
                     /gene="hslV"
                     /locus_tag="RD488_000593"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HDT7656692.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15813..16718)
                     /gene="xerC"
                     /locus_tag="RD488_000594"
     CDS             complement(15813..16718)
                     /gene="xerC"
                     /locus_tag="RD488_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDT7656693.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16916..18292)
                     /gene="trmFO"
                     /locus_tag="RD488_000595"
     CDS             complement(16916..18292)
                     /gene="trmFO"
                     /locus_tag="RD488_000595"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HDT7656694.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18261..20339)
                     /gene="topA"
                     /locus_tag="RD488_000596"
     CDS             complement(18261..20339)
                     /gene="topA"
                     /locus_tag="RD488_000596"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDT7656695.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20461..21318)
                     /gene="dprA"
                     /locus_tag="RD488_000597"
     CDS             complement(20461..21318)
                     /gene="dprA"
                     /locus_tag="RD488_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDT7656696.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21374..22141)
                     /locus_tag="RD488_000598"
     CDS             complement(21374..22141)
                     /locus_tag="RD488_000598"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDT7656697.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22134..22994)
                     /gene="ylqF"
                     /locus_tag="RD488_000599"
     CDS             complement(22134..22994)
                     /gene="ylqF"
                     /locus_tag="RD488_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDT7656698.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(23088..24047)
                     /locus_tag="RD488_000600"
     CDS             complement(23088..24047)
                     /locus_tag="RD488_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7656699.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            24319..24717
                     /locus_tag="RD488_000601"
     CDS             24319..24717
                     /locus_tag="RD488_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7656700.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24996..25496
                     /locus_tag="RD488_000602"
     CDS             24996..25496
                     /locus_tag="RD488_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7656701.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25579..26130)
                     /gene="lepB"
                     /locus_tag="RD488_000603"
     CDS             complement(25579..26130)
                     /gene="lepB"
                     /locus_tag="RD488_000603"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7656702.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(26282..26509)
                     /locus_tag="RD488_000604"
     CDS             complement(26282..26509)
                     /locus_tag="RD488_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDT7656703.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26506..27024)
                     /gene="msrA"
                     /locus_tag="RD488_000605"
     CDS             complement(26506..27024)
                     /gene="msrA"
                     /locus_tag="RD488_000605"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7656704.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(27044..27757)
                     /locus_tag="RD488_000606"
     CDS             complement(27044..27757)
                     /locus_tag="RD488_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HDT7656705.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27760..28656)
                     /locus_tag="RD488_000607"
     CDS             complement(27760..28656)
                     /locus_tag="RD488_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7656706.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28814..29656)
                     /locus_tag="RD488_000608"
     CDS             complement(28814..29656)
                     /locus_tag="RD488_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7656707.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29788..30441
                     /locus_tag="RD488_000609"
     CDS             29788..30441
                     /locus_tag="RD488_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDT7656708.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30504..31031)
                     /locus_tag="RD488_000610"
     CDS             complement(30504..31031)
                     /locus_tag="RD488_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7656709.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(31051..31998)
                     /locus_tag="RD488_000611"
     CDS             complement(31051..31998)
                     /locus_tag="RD488_000611"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDT7656710.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(32010..33896)
                     /locus_tag="RD488_000612"
     CDS             complement(32010..33896)
                     /locus_tag="RD488_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7656711.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(34056..36134)
                     /locus_tag="RD488_000613"
     CDS             complement(34056..36134)
                     /locus_tag="RD488_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDT7656712.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(36147..36422)
                     /locus_tag="RD488_000614"
     CDS             complement(36147..36422)
                     /locus_tag="RD488_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656713.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36784..37239)
                     /locus_tag="RD488_000615"
     CDS             complement(36784..37239)
                     /locus_tag="RD488_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656714.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(37393..38601)
                     /locus_tag="RD488_000616"
     CDS             complement(37393..38601)
                     /locus_tag="RD488_000616"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDT7656715.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38713..39045)
                     /locus_tag="RD488_000617"
     CDS             complement(38713..39045)
                     /locus_tag="RD488_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7656716.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            39193..40068
                     /locus_tag="RD488_000618"
     CDS             39193..40068
                     /locus_tag="RD488_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7656717.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(40150..40731)
                     /locus_tag="RD488_000619"
     CDS             complement(40150..40731)
                     /locus_tag="RD488_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDT7656718.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40737..41996)
                     /locus_tag="RD488_000620"
     CDS             complement(40737..41996)
                     /locus_tag="RD488_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7656719.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41998..43044)
                     /locus_tag="RD488_000621"
     CDS             complement(41998..43044)
                     /locus_tag="RD488_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656720.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(43279..43554)
                     /locus_tag="RD488_000622"
     CDS             complement(43279..43554)
                     /locus_tag="RD488_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDT7656721.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43797..45107)
                     /gene="der"
                     /locus_tag="RD488_000623"
     CDS             complement(43797..45107)
                     /gene="der"
                     /locus_tag="RD488_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDT7656722.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(45289..46518)
                     /gene="rpsA"
                     /locus_tag="RD488_000624"
     CDS             complement(45289..46518)
                     /gene="rpsA"
                     /locus_tag="RD488_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDT7656723.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(46653..47333)
                     /locus_tag="RD488_000625"
     CDS             complement(46653..47333)
                     /locus_tag="RD488_000625"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDT7656724.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(47382..48017)
                     /locus_tag="RD488_000626"
     CDS             complement(47382..48017)
                     /locus_tag="RD488_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7656725.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(48083..49486)
                     /locus_tag="RD488_000627"
     CDS             complement(48083..49486)
                     /locus_tag="RD488_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDT7656726.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(49473..50504)
                     /locus_tag="RD488_000628"
     CDS             complement(49473..50504)
                     /locus_tag="RD488_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656727.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            50535..50756
                     /locus_tag="RD488_000629"
     CDS             50535..50756
                     /locus_tag="RD488_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDT7656728.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(50921..51658)
                     /locus_tag="RD488_000630"
     CDS             complement(50921..51658)
                     /locus_tag="RD488_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HDT7656729.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51811..53151)
                     /locus_tag="RD488_000631"
     CDS             complement(51811..53151)
                     /locus_tag="RD488_000631"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDT7656730.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(53388..54911)
                     /locus_tag="RD488_000632"
     CDS             complement(53388..54911)
                     /locus_tag="RD488_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDT7656731.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(55290..55901)
                     /locus_tag="RD488_000633"
     CDS             complement(55290..55901)
                     /locus_tag="RD488_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7656732.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(56024..56149)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(56231..56947)
                     /locus_tag="RD488_000634"
     CDS             complement(56231..56947)
                     /locus_tag="RD488_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7656733.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(56953..57522)
                     /gene="scpB"
                     /locus_tag="RD488_000635"
     CDS             complement(56953..57522)
                     /gene="scpB"
                     /locus_tag="RD488_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDT7656734.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(57506..58303)
                     /locus_tag="RD488_000636"
     CDS             complement(57506..58303)
                     /locus_tag="RD488_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDT7656735.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(58273..58644)
                     /locus_tag="RD488_000637"
     CDS             complement(58273..58644)
                     /locus_tag="RD488_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7656736.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(58663..59550)
                     /gene="xerD"
                     /locus_tag="RD488_000638"
     CDS             complement(58663..59550)
                     /gene="xerD"
                     /locus_tag="RD488_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDT7656737.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(59646..60119)
                     /locus_tag="RD488_000639"
     CDS             complement(59646..60119)
                     /locus_tag="RD488_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7656738.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(60224..61087)
                     /locus_tag="RD488_000640"
     CDS             complement(60224..61087)
                     /locus_tag="RD488_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7656739.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(61283..63382)
                     /locus_tag="RD488_000641"
     CDS             complement(61283..63382)
                     /locus_tag="RD488_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7656740.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT        17228 a        13391 c        10843 g        22075 t
ORIGIN      
        1 atttatgtgg caaagaaaaa acaaacaaaa taaaaagcat tttgaagcct gactattacg
       61 acttcataaa tgctttttta gttttaaaca cttcaatcta aaagaataac ccaagattgg
      121 ataaattatt aatgactcgc cattcgtttc ttagtgattc tggattatca aatggacttc
      181 ctaatctaat cagctagttc ttcccataaa atgccatact tgactgaatc ataatattga
      241 ttatttaaaa atctaacttt tcttatcact acttcctttg tcattccaca tttctcacca
      301 tttttttgca ttcctttgtt tccagaccat gtagtgaatc taataggtgg tagataggca
      361 aaatactcaa ataattcttt taaccataaa ggaagagaaa ggctcctcct gcaagagtca
      421 gtataatttt tgcttactgc tctcttaggt tttactcact aaaactgttc catattcttt
      481 gatataagaa aatgcatgcg gtataaattt cttgctcagc tcagaaaaga tttgtcgttt
      541 aagaaaggcc atttcctcca ttgtcaatga aggatccaat gttggtaatt caatctcaaa
      601 attgtttttt tcgacaatag gtaattctaa tgtgaatgat tcttcttcct ttatagtatt
      661 cgtcacaagt agagactgat ggaaaatact aggccggcga tttttatatt tattcttacg
      721 tatcctgtca acgataactt ctatttgatc aaaaaagtac gattcattta cgtctccaat
      781 aagttcggct aattctttga atgccttcgt tacaggaagc tgattcttct gtacaaaaaa
      841 gtaattagcc aaagtaagcg ggaagtgttc tatagaggaa agtgtgataa aacggtactt
      901 ctcatttcct gcagttgtcc tcagcaattc tgtctctcgg ctgtttctta ctccataaaa
      961 atacgcttct ttccgttcat cttcgaaaca atacgcccaa ataacttctc ccatcgctaa
     1021 tttttgttca tcaacagaga gtctcttcaa ttgttcagct atggtttcag cagccgaagt
     1081 ggcttgttgc aagtaatctt taggatcaaa tattggaaag ttcaaatgat atcttcgttc
     1141 ttccctcttg attaatcctg catcgatcaa taaatcaaga aaatgggaaa atttattttg
     1201 cgaaaattct tttttcaatt ctcttagaat cgtttcttgt tctcgatgtt catatagata
     1261 atcggtcaat gaagaaaaaa gcggatcatc ggtcagtttt tgataaaagt tttccttatt
     1321 ttttgaataa tagttcatat atgttctctt ttctatccgt tttattttac ttaaaaggct
     1381 tttacgtaaa aaggaggaag aacaagagtc ataattgact gttattctcc tccatttctt
     1441 cggcctttag tatgttctat gtttcttttt atatcaatcg cttatccatt cattttgaat
     1501 gcttcatact accatttgat tagctaaata cagccgtcaa ttgaggtacg acttgttttt
     1561 tacgtgaaac gacaccttta agcaaagcac ggttgttggt caaagttgtt tggaaagctt
     1621 cttctacttt ttcttttcct ttaccagcaa caagtaattc tgaatcactg tctaagatgt
     1681 ttgtgacaac taatacgaac agatcgtagc catttgcttt catttcatct tccattgctg
     1741 cttctagctc tgcttgtcga tccatcactt cattaaggtc cactgtattg acttgagcga
     1801 tacgaacgtt ggaactgccc attgggaaac tttttgcatc caaatcaaga agaaccgcag
     1861 ctgatttatc acttagattt gttcctgctt tcaacatttc aagtccataa gtgtttagat
     1921 cgacttcagc gattgctgca agttcttttg cagctgcttc atcttcaggc gtacatgttg
     1981 gtgatttgaa caacaatgta tctgaaatga tagctgagag catgattcct gcgatttctt
     2041 taggaattgt tacttggttt tctttatata gttttaaaat aatcgtactt gtacatccaa
     2101 ctggttctgc acgatagtac aatggattag ctgtttcaaa gtttgcaata cgatggtggt
     2161 ctactacagc taaaatattt acttcgctga tatctgaaat actttgttgg aattcattat
     2221 gatccacaag catgacatct gcattttctg ctttagctga ctctactact cgtggtgcag
     2281 atagctgaaa gtggtctaat gcgtattgtg tttcttcatt aggtgtacct agagcaactg
     2341 cttctgtttc tttacctaat tcattttgca agtgtgaaaa cgcaatggct gccccgattg
     2401 catctgtatc tggattttgg tgaccaaaaa ctaaaatttt tgacatgtca ttcgctcctt
     2461 tgtgatttct cctatttaat aatagcaaaa aaacggaaag aagcaatact tatcttcttt
     2521 ccgatgcgac ctatcgcgtt aaatattttg tatactcttc tgtatgaagc aatcgtttag
     2581 cattttcgac acgttctttt gtaggtggtt cgatcccttc taatggatat ttcaaaccaa
     2641 gtgtttccca cttgtatttt cccatcgtat gataaggaag aatctctact ctgtctacat
     2701 ttgacaaggt ttgaataaag ttgtctagtc ggatcaaata ttcatcataa tcacttcgct
     2761 caggaactag tacatggcga atccaaaccg gtttgttgat ttttgacaaa tattgagcca
     2821 tttctaaaat attttcattg tcccaatgcg ttagtttttt atgctcttca ttatcgatgt
     2881 gtttgatgtc aaataacagt aaatctgtat acttcatcaa ttcttgaaaa cgtgaaaaga
     2941 aaggttcttc atacgtaaaa ggttttccgc atgtatccaa tgtagtatgc atcttccgct
     3001 cttttgcttt tttaaatagt tcgatcaaaa aatcgatctg caatagaggt tctccaccac
     3061 taacagtaat accaccttta tctccccagt aaggtctgaa gcgttctgct ttatctaaaa
     3121 gttcatctgc tgtgtattct ttccctccgc caatattcca agtatctgga ttgtgacaaa
     3181 attggcaacg catgcggcat ccttgcataa acacgacaaa gcgcagtcca ggtccgtcta
     3241 ctgaaccgaa agtttcgata gaatgaacat agccgattgt tttttcttcc atttaagttc
     3301 acatcttttc tttgatttca ttttaagtac aagttagctg tcgaagcgaa gctttctgaa
     3361 caaaattttt cgcaattgcc gcttcgttat gtgtaaaatt tacagggacg gaacatacaa
     3421 gtcctgcccc tgtaaatcgt ttctttcaaa taagcatact gattattcga ttttgatgcg
     3481 atggctattc aacgtccttt cgacgctaag tcgaaaaact tttttcacga actttttaca
     3541 ttctgtcgtg tgaagttctc atcaagacat ctaattgttg ttctcttgtc aagtcacgga
     3601 atttaactgc ataaccagat acccggatcg tcaagttcgg atatttcatt ggattttcca
     3661 ttgcatcacg caataaatca ttactgaata cattgacatt caaatgataa gctccttttg
     3721 agaagtatcc atctaagaca ttacgcaagt tttcgattct tgtatcttgt tcttttccaa
     3781 gacctgaagg attgattgtt tgggtatttg aaattccatc caatgcacag ccgtaattca
     3841 ttttagctgt tgagttcagg ctagctaata acccactttg ttccgcattg taacttggat
     3901 ttgctcctgg cgcaagtggt tttccagctt cacggccatc aggagtattt cctgtatttt
     3961 taccgtaaac aacatttgaa gtaatcgtca ataatgaagt tgttggtttt gagttgcggt
     4021 aagttttatg acgtttgatt tgtcccatga agtattccaa gatccatgaa actaattcat
     4081 ctgcacggtc atcatcattt ccgtatttag ggaagtcgcc atccacttca aaatcaactg
     4141 ctattccttt ttcattacgg attgctttta cttttgcata tttgatcgct gacaagctgt
     4201 ctgccgcatg agagatccca gcaatacctg tagcaaatgt gcgttgcaag tcagaatcca
     4261 tcaaagccag ctgagctgct tcataagaat atttatcatg catataatga atgatgttca
     4321 acgtattgac atatagttct gctaaccaat ccatcatatt catgaagtta tgtttcactt
     4381 cttcaaagtc tagtatttct gatgtgattg gacgatattc tggtccaact tgggcgccag
     4441 tcacttcatc gactccgcca ttgatggcat ataatagtgt tttagccaag ttagcacgag
     4501 cgccaaagaa ttgcatgtct tttccgacaa ctgttcctga tacacagcaa gcaatcgcac
     4561 aatcatcaga accccattgt tcacgaagct gattatcatt ttcgaattga atcgaagaac
     4621 tttcgatagc gattctgcta gcatatgttc tgaatccttc tggaaggtgt tcagaataca
     4681 aaacagtcaa gtttggttct ggtgaaggtc ccatatttgt taatgtatga agcagacgga
     4741 aatcattctt tgtaactaat gaacgaccat ctaatcccat acctgcaatg gataaagtag
     4801 cccagatagg gaatcctgag aataattggt tatattcagg tgtacgcgcg aatttgacca
     4861 tacgtaattt cattactaag tggtcgatca attcttgtgc ttctttttct gtgattactc
     4921 cattatccaa atcacgttgg atatagatat caaggaatgc tgagatacgt ccgattgaca
     4981 tcgcagcacc attttgtgat ttgattgctg ctaaatatcc gaagtatagc cattggacag
     5041 cttcttttgc atttgcagct ggtttagaaa tatcatagcc atatttcgca gccatttctt
     5101 tcatttgcgc taatgcacga tattgttcag tgatttcttc acgtaaacga atcacttctt
     5161 cactcattgt atgataacca gtcatatcat gatctttttt cttttgttcc atcaaatagt
     5221 cgattccata caatgccaca cgacgatagt caccgatgat acgtccgcga ccgtaagcgt
     5281 ctggaagccc tgtaatgatt ttgtttttac gagcagcacg catttcagca gtataagcgt
     5341 caaatacacc ttgattatgt gttttgcgcc agtcagtgaa aatatgtgtc aattcatcgt
     5401 ttggtgtata gccattgctt tttagcgcat tgttagccat attgattccg ccgaacggca
     5461 tgaatgcttg tttcaaaggt ttgtctgtct gtagaccgac gattttttcc aaatctttat
     5521 ccaaatagcc tgcatcgtgt gaagtaatag ttgatacgat ttctgtgtcc atatcataga
     5581 caccgttacg ctcgaattgg atatcattta acttttgcaa ttcatcccat aatttttctg
     5641 ttgcttctgt tgggccttcc aaaaagctgt catcaccgcg atattcagtg tagttatttt
     5701 gaataaagtc tctagtgtct acgccttctt tccatttggt acctttaaat ccattccatt
     5761 gctccattgt atggacctcc taaatttctg ttttatgtaa cagtttttac gtgattagta
     5821 taacacagca ccctatcttt gcaagggttt tcttgttttt tatttaacaa tttttatgtt
     5881 ttatttacat atatttaaat caacgttgac ataccaacat ttaagcattg tgaacacttt
     5941 catctttttt tgcaaacgta taaggattta ttaaaaatga atgaaaaaga gacgccacct
     6001 gtattaatac agatggcgtc tcttcattaa aatactacaa cagttacgac tcgatgaaaa
     6061 tctcaggagc atcgataact tcgatgactt ctccaccttt tttctcatcc atcgcaaatg
     6121 atccattcga tgttcgatca cctataggga aatcagttgg gtcaatcgtt aactgctgcc
     6181 ctttttgatt catcaaggtt atttcttttg atcttccttc cgacatatag ataatacggt
     6241 gcggattttt tttcagctca cgcatgaccg tcactccccg cttcgcacgt gaagtttggc
     6301 tgatttcttg agcaagcatg cgtttaacag ctcctcgctg agtaacgatt acgatcggcg
     6361 tatcaccttc tgctaacaca agcagcccgt tgataatcct atctccatct ttcaaattca
     6421 tagacttcac tccagctgcc tttgctccaa caacgggaac atctgttaaa ggatagcgca
     6481 aacccattcc ttgatgcgtt actaagaaaa catctaagcc tggctgatct tctttcagat
     6541 acacagcaat cagttcatct tcttccgcct ttagcttcat acagctgagc ggacggctct
     6601 tataggtgcg ccatggttcg aactctgtca ttcgtgtttg cttgatcaat ccattcttgc
     6661 tgatgaatac aaatgttttc tctgcttgaa ttttttgata tgggaaaaca gctaaaatcg
     6721 attcgtctac agacagattg gagattgttt gagaaatgtg ctcaccagca tctttccatt
     6781 tcaaatcggg tagttcatgg acagggcggt agatcacatt tgctttattt gtgatcagaa
     6841 gaacatggtc caatgtactc aattcacctg agtatagcaa gtagtcgcct tctcgcatcc
     6901 cgatttcttc tggtttggaa gcactataag aacgaaggct tgttcgcttc acatagcctt
     6961 ctcgcgtcac actgacaatt acgtcttctt gtgccactaa gacttgcgta tcaattttga
     7021 tttcttcgat ttcgtcttcg attgtcgtta gacgagcgga agaataattt tttttcactt
     7081 ctcgcaattc ttttttcata acagagaaaa gctctttgtc atttgaaagg attttattca
     7141 actctgtgat ttgcgcaatc aagctttcgg attccttttg aagctctgtg atatccgtgt
     7201 tcgtcaaacg gtataattgc aatgtgacaa ttgcttctgc ttgttcttct gtaaattgaa
     7261 agacgtcgac taaattcttt ttggcgtctt ttttgtcttt actttcacga atcgttgcga
     7321 ttacttcatc cagaatcgat aaagctttca tcaatccttc tacgatatgc tgtctttttt
     7381 gagctttggc taaatcgaat tgactacgtt ttgttatgac ttgctttcga tgctcgatat
     7441 aacttcttaa aatgtctttc agtccaactt gatgcggagt catatggtcg atagcgacca
     7501 tattgaaatt gtaattgatc tgtagctcag tgtttttgaa caaataattc aaaattcctt
     7561 gagcattggc gtcttttttc aattcgacga caatttgcag acctgttcta tcactttcat
     7621 ctcgtacttc agctattcca tcgattttct tattcaaacg gatctcatcc atttttttca
     7681 ccaaggtcgc tttatttact tcatatggga tttctgtgat cacgatttgc tgtttattac
     7741 ccttcattgc ctctatcttt gttttcgaac gaagaataac ttttcctcgt cctgtttcat
     7801 aagctttttt gatttcatct tttccttgca agatccctcc tgttggaaag tcaggtccag
     7861 gaatatattc catcaatttt tcaaggctcg cttgtggatg atcgatcata tagattgtgc
     7921 catcgatcac ttcagctaag ttatgagtcg ggatttctgt tgcatatcca gcagatatac
     7981 ctgtcgatcc attgacgaga aggtttgggt atcgagctgg aaggactgtt ggttcttttt
     8041 ctgtatcatc aaaattccac acgagatcga ctgtttcttt ctcgatatct gctagcatct
     8101 ctccacttaa cttggataat ctggcttcag tataacgcat cgcagcaggt ggatcaccgt
     8161 ccatactccc gttattcccg tgcatttcga tcagtacttc ccgcaacttc cagtcttggc
     8221 tcatgcggac catcgcttca taaatactga tgtcaccatg aggatgataa ttccccatga
     8281 tatttccgac agattttgct gatttacgga atcctttgtc atacgtattg ccatctttgt
     8341 tcatggcaaa taatatccgg cgttgcactg gcttcaatcc atcacggata tcaggcagtg
     8401 cacgttcttg gataatatat ttggaataac gtccgaagcg gtcacccatc acttcttcta
     8461 aagttaattc ttgtacttct tgtcgatttt ccatcaggtg acctcctatt ctacttcaaa
     8521 taactgattg ttttcatttt tatctgctcg ttcttcatct aataaatcat tagaaactga
     8581 aggagagatt tcagtatcct cttttttatc taagatactg ccatcttctt cgagcgtaaa
     8641 ttgcacgtga ttttcgatcc attttcttcg aggttctact ttgtcaccca tcagtgtggt
     8701 tactcgacgt tcagcttgcg cagcatcatc gatacggacg cggatcaacg tacgggaagt
     8761 cggatccatc gttgtttccc acaattgttc cgcattcatc tctccaagtc ctttatatcg
     8821 ctgcagcata tatcctttgc cgactttttt aatcattgct gccaattcgt catctgtcca
     8881 cgcatattca atgacttgct tctttccttg tcctttggat actttatata aaggcggtaa
     8941 cgcgatatat actttcccag cttcaatcag cggtttcata taacgataaa agaaagtaag
     9001 cagtaatact tgaatatggg cgccgtctgt atccgcatcg gtcatgatga ttactttgtc
     9061 gtaattacag tcttcgatag aaaactcagg accgactcct gcaccaatcg tatagatcat
     9121 cgtattgatt tcttcatttt tcaagatatc ttgcatttta gctttttcgg tattgatgac
     9181 ttttcctcgt aaaggtagaa ttgcttggaa ctttctgtct cttccttgtt tagcagatcc
     9241 gccagcagaa tccccttcga ctaaatacaa ttcatttttc ttagggtttc gggattgtgc
     9301 gggtgtcaat tttcctgaaa gaagagattc gcctttttta cgcttcttcc catttcggct
     9361 ttcttctctg gctttacgtg ctgcttctct cgcttctctg gctttgattg ctttacggac
     9421 caacatctgg ctcatttcgc tattttcctg caaataaaag cccatttgtt cactgatgac
     9481 gttatctact acggtacgag caactggcgt accaagtttt tcttttgttt gcccttcaaa
     9541 ttgcagaaga ttttcaggta cacggataga aagtacagca gctaaccctt ctctgaaatc
     9601 actaccttcc agattcttgt cccgttcttt cagcaaacca acttttctcg catattcatt
     9661 ataagatttc gtcatcgccg ctttcatacc agcttcatgg gttcccccat cttttgtccg
     9721 aacgttattg acaaaagata aaacattttc tgaataaccg tcattgtatt gataagcgac
     9781 ctctacttcg ataccttctt tttctcctga aaaataaaca actggtgtca atgtatcttt
     9841 ttcttcattc agataatcaa caaattcttt gattccttct tcgtaatgaa aaatttcctt
     9901 gactggttct tctccacgaa gatcagaaag agagatttta acgcctttta gaagaaaggc
     9961 agattctctt aaccgttcgg ctaaaatttc atatgaaaat ttcgttgtac tgaatattgt
    10021 atcatctggt aaaaaatgga cagtcgtccc gtttgctttt tttgtttttc ctatcttttt
    10081 caaagtaccg tcaggtttac cgccgttttt aaatttctgc tgatactcta cgccatctct
    10141 aacgatcgtt acaattagcc atttcgataa ggcatttacc acactggctc ctacaccgtg
    10201 cagtccacca gaagttttgt accctccttg accaaacttt ccgccagcat gcagcacagt
    10261 aaaaatcact tcaactgttg gtattccgga agcatgcatt cctacaggca tcccacgtcc
    10321 gctatctgca acagttatac tattgtcttc atggatggtc acatcaatct cactgccata
    10381 acctgataat gcttcgtcaa ctgcattatc gacgatttca tagactaaat gatgcaagcc
    10441 tcggctgtca gtggatccaa tgtacatccc tggtcttttt ctaactgcct ctaatccttc
    10501 caatacttgg atggacgagt cattgtattc gttgtttact ttttttgcca aggcaaacgc
    10561 tccttcaata atactttgcg gcaaaaccgc accacgatta tcatactaga aaaggtcgtg
    10621 aaaaaaaaga gggtagacga gaaatcaatt ttaattatct cctaaccgct ttttcgacat
    10681 tcccctctat cgatcatctc ttctttgtgg tcatttttat ttttggtttt ctttcaactt
    10741 accaagttca atcttaatac aacgatccat tacgatatct gtacgtcctg cttttcttag
    10801 catctcagct gcttctttgt tttcaatccc taattgtgcc cagaacactt tagcatcagt
    10861 tttcaaaaaa tcacctgcta tttcaggtaa aaattcactc cgtctaaata catctacgat
    10921 atcgattgga tcatcgattt ctgtcaaatt cgcatagact ttctcgccta gaatttcttc
    10981 accagccaat aatggattta ctggtatgat tttatatcca ttgtcttgca atacctgtgc
    11041 aaccatgtaa cttgttcgtt ctggtttatt gctcaagcct acgacggcaa tattttttgc
    11101 ttcttccaaa tagttgaaaa tcgtttcttg tgttggattt tttacagaca tttctgccac
    11161 cccttgcttt tctttttatt ccatctatta tacttgtatc tttcattttt tcaattgttc
    11221 ctgttaccta ttcatgctaa aataaaggat agttttcaac ttgaaagagg gtaaaaaatg
    11281 aaattgatct tattacttat tttagcatat cttttaggtt ctattccttc cggtgtctgg
    11341 attggcaaat tgtttttcaa aaaagatatc cgacaacacg ggagcggtaa tactggaacg
    11401 accaatacat ttcgtgtatt aggcaaaaca gccgggattg ttgtcctgct tatggatatt
    11461 ttaaaaggta cattggctac ttgtttgccg atgatcttcc acctttctgg gattaaccct
    11521 ctttggtttg gggtatgcgc cattcttggc catacatttc cgatttttgc tgggttcaaa
    11581 ggaggaaaag ctgttgcgac aagtgcagga atgcttttag gatttaatcc tgtatttttt
    11641 gtttattctt gtatcatctt tatcgttagt ttattttgta caagtatggt gagtttgagc
    11701 agtatgatca gtgcagtatt gatcacttta tctacgatcg tccttcctta tgtagctcct
    11761 gtgattttgg ctaagcccaa ttggttactg acgatcattg cctttttagt ttcttccttt
    11821 atcttttatc ggcataaaga caatatcaag cgtatcagaa accatactga aagtcgaatc
    11881 ccgtttggtt tgaatagcag caagaaaaaa tcctgatact ttttcattcc aaagagataa
    11941 aacgggagtg tgacaaatcg atgtcacact cccttattac ttacaggata gcttttttac
    12001 acaccttggt aaacggtgtt ccctgctaac ttctcggtca caacctctta cttcactgtg
    12061 atggaatatt ttgtcttgaa gatttcatgg gcacctagtt gattgatccc tactttttcc
    12121 atcaagtttc cactactgtt caccgtgtca gcgattccgc accacggttc gatacaaacg
    12181 aaaggcgctt cttttggata aggagaccag atccctacat aaggcatatc tttatagctt
    12241 aaagttacgc tatgggaaga tttttcactt cgaatggcgt acgcatttag accccttgtt
    12301 tcaaaaacca aggcatcttg ctcaaaaagt tcacgattca aagccagatt cgtatttgtc
    12361 tgacctaacg tcttttgatc catatcgatg aatgggcctt tcaatggtag gcgtaatctt
    12421 gatttcaatg gagaaaatgc cagatagaaa tcttcaaatg acaatccttc ttcaagaggt
    12481 acattgaaag caggatgtcc accgatagaa aagaacattt ctttttcacc ggtatttgcc
    12541 acttgataat gaaccgtgat gccgtctcct cctaattcat agctgatcac taattcaaaa
    12601 tcaaatggat acttttctaa tgtctccggc gtactcctta agatgaaact agccatttct
    12661 tgtccatgtt caatgacttc aaaatccata tcccgagcaa atccgtgttg ccccatttga
    12721 tatgttttcc cttgataaac atactgatca tcttttaaac gtccaacaaa agggaataaa
    12781 accggtgcat gtctgcccca atacgctgga tcaccttgcc agatatactc taaaccatgt
    12841 tcttttgatt tcagactgat caattccgca ccgtgttcag cgatttcggc gatcagctgg
    12901 tcattttgaa taataacagt cattgccatt cctccaactt cgacttactt tttaaaatgg
    12961 gaaggctgga acaaacattt ctatctgccc cagtcccctt acttctaata actgtgtttt
    13021 gctaactcgt ctttaaaacg ggaattcaat acttttaaat aagttccctt catgcctaac
    13081 gaacgagatt caatgattcc agctgattcc aattttcgta aagcattgac gatcacagaa
    13141 cgagtgatgc cgatactatc ggcaatatta gaagcagtca gacgaccttc atctccatcc
    13201 aatgcttcaa agatagcttg tacagccttc aattcgctat aagataatgt gttgattgcc
    13261 atttggacag ccgttgcact ccgtacatct gcttcgatgc ttcgagactt ctgataaagg
    13321 atctgcatac cgacaaccgt agctccatat tctgctaaga ctagatcgtc atctgcaaac
    13381 gattgttcca tacgagataa gataatcgta cccaaacgtt cgccagctcc aaagatcgga
    13441 acgacagtcg tcagaccaaa tggatatttc tctcttgact ctaccggaaa tgcagtaata
    13501 tcactagtaa ttgggatatt agcttcagtt ttcatcaact gtgccactgt atcagtataa
    13561 gattcaggaa attgtttctc aacaaacatt gttttgattc gttcattgtt cacatcgtga
    13621 cgttcattat aacctagtaa tactccgtca cttcctatga tataggtgtt gctgtcaaga
    13681 ataccaccta gtgtgacagc cattttatcg taaggcaaat ctgcttgcat gtcaaaagta
    13741 ttcttttgct gcaaaagtgt gtttatcttg cgggttttcg ttagcaagtc tgtcattgtc
    13801 gtcctccgat tttttataaa atatagcgac ttaaatcttc atttgccgca attgagccaa
    13861 gtttgtcatc cacatatgct tctgtgatcg ttatttctcc catttgcata tctggtgctt
    13921 caaataatag atcttctagt agtttttcca aaatggtatg cagtctgcgt gcgccgatat
    13981 tatctgtgtc acggttgaca tcgaaagcga tttgagcgat ccgttcaatt gcttcttttg
    14041 taaacgtaac tgacacattt tctgtaccga tcaacgcgac gtattgtttt actaaagcat
    14101 tatttggttc ggtcagaatc ttcacaaaat cttcagctgt caaatcatct aattctaccc
    14161 gtatcgggaa gcgtccttga agttctggaa ttagatcact tggtttagac aaatggaaag
    14221 ctcctgaagc aatgaatagg acgtgatctg tttggatgat cccgtatttt gtgtttactt
    14281 gtgaaccttc gacaattggc aatatgtctc tttggacgcc ttctctggat acttctccag
    14341 attgctgtga tttagaagtg atcttatcga tttcatcgat aaaaataatt ccactttctt
    14401 ccgctaattt gattgcctca ctatggatat cagcatcctt gactaatttt gctgattctt
    14461 ccttgatcaa taactctaaa gcttctttga ctgttaccgt ccgttccact tttttcttcg
    14521 gtgtcaaagc acctagagtt tcatttaggt cgatccccat ttgctccaat ccattgttca
    14581 tcattggtgc aggtttcttt tggtcttcaa cttcaatggt tacttcacga ctatccagta
    14641 aacccttttg tagttgttcc aagactgtac ggcgattgat tcgaatatct tctgtcactt
    14701 cttcttgcgg ttcagcggta ttttgctgac tagcattaaa aagattcatc atttgttcaa
    14761 attgattagt ggattgtttc tgttcttttt tgataccagg taccaagatt tttaccaaac
    14821 gtttttctgc atttttttta gcacttgtgt atacacggct gtactgctct ttttctacga
    14881 tttggatcgc attttctact aaatcccgaa ccattgattc tacatctctt ccgacataac
    14941 cgacttcagt aaattttgtt gcttcgactt tgacaaatgg tgcattgacg atttttgcca
    15001 aacgtcgtgc gatttctgtt ttaccgaccc ctgtaggtcc gatcatcagc atattttttg
    15061 gtgtaatatc ttgttgcatt ttttcatcta actgcaaacg gcgatagcgg ttacgcaaag
    15121 caacggcaac agattttttt gctgcgtgct gtcctacgat atattcatct aattcactta
    15181 cgatttgtct tggtgtttgt tttaattcat acatatctac tcacctctta cagttcttct
    15241 acgataatat tatgattagt aaagatacag atatctgcgg caatatttaa cgcattttct
    15301 gcaatttctt tcgcactcat gtcgttttga gcatagtttt tcattgctcg ggctgcagcc
    15361 aacgcaaaat tccctcctga tccgatagct aagataccat catctggtgt gataacttct
    15421 cctgtacctg aaacaagaag catttcttta tcattcatta cgatcagcat cgcttcaagt
    15481 ttttgcatag attgctgtgt ccgccattct tgagctaatt cgacagctgc gcgttgtaga
    15541 ttcccgttat attcgtttag tttgccttca aatttttctt ctaaagtaaa cgcatctgca
    15601 acacttccgg cgaaacctac aacaacttct ccattgtaga tacgtcgtac tttctttgca
    15661 gtgcctttca tgacaacaga ttcacccatt gttacttggc catctccagc catagcaaat
    15721 ttcccgtctt tttcgacggc acagatagtg gttgaatgaa atggtgattc gaccatgttt
    15781 gtttcctcct aaatttgttc ttttccttat ttttacgctc ttggatggaa agaacgatag
    15841 tttttttgta aactttcttt tgttacatgg gcatagatct gggtagtcga taaattggca
    15901 tgtcctagca attcttggac tgtccgcaaa tctgccccat tatttaataa atgagtagca
    15961 aatgtatggc gcagcatgtg aggatggata tcactatcca aactgctttt tttgatcatt
    16021 tgattcaaga catattcaat tccagtaggc gtgattggtt ttccatgatg attcacaaaa
    16081 acgatatcat gctcttcgtg atattttgtc atcaatacct ggcggccttc cctgaaatat
    16141 tcttgcagag catcttgagc aaaagaacct agaggagcat atctctcttt gttcccttta
    16201 ccatggatca acatgacctc tgaatcaaaa tcaatgtctg ataccgacaa actgctacac
    16261 tcacttaaac ggatgcctga cccgtaaagg acttccagta aagcgcggtt cctcaaatcc
    16321 aaaggactat ctcctgctac gctgtcaaaa agtgcttgca tttcattttc ataaaaaaaa
    16381 cgtggcagtc tcaaattttt ctttttgaga tgaacgtaag aaaatggatt ttcttttatc
    16441 acttcttctt tgagaagata ctgataaaac gaacgtaggc tggctatctt gcgactgata
    16501 gaatttctgc tatagctagg acgatgatca gctaatgcac tcaaatagac acgaaccgta
    16561 aaatattccg ccttcagcag atcagcgtct ccagattcct ccaaaaaatg tttgaaatgg
    16621 agaatgtctt cttcatatgc ttctttcgtt ttttctgaat atcctctttc gacaatcaaa
    16681 taacgcaaaa atttttgttc ccacgtggct tctgtcattt tctcaccttc cttttgtccc
    16741 agagaataat ttagcacagc gtttataaaa agacaaataa attgtcagaa tttaaccaat
    16801 atttctaagt ttgttcacaa ttggcgcaat tcctcacatt ttgtttgaga aattcttaag
    16861 aaaaacgcaa gaaaaagagc gagactatcc gtctcaccct cttcatggag tttccttact
    16921 catttgggat tgcagttttt tctaattctg tttttattgc ctcattagct tttaaagctc
    16981 gttgtgcaat tgcttcatat cttgcttttt tgtctcgaat gcgctctggc agttcaggaa
    17041 acagaccata gttggcattc atcggttgga aatgttttcc ttccgcatga gtaatgtagt
    17101 aagccatact tccaatagct gtttcttgtg gaaactcgac tggttccatt tcttttgcta
    17161 agcgtgcggc gttgattcca gcaagtagtc cgctcgctgc actttcaaca tagccttcta
    17221 caccagtcat ctgacctgca aagaacagat cttcgcgttt cgttgattgg taagtcggtt
    17281 tcagcaattc tggcgaattc ataaagctgt ttcggtgcat cacaccatag cgaacgaatt
    17341 cagcattttc taacccagga atcatccgga aaacacgttt ttgctcgccc catttcaagt
    17401 gagtctgaaa gcccacgatg ttgtataaag aagctgcagc attgtcttga cgcagctgga
    17461 taacagcata aggacgtttg ccagttttag gatcttccaa tccaactggt ttcataggtc
    17521 cgaaaagcat cgttttgaat cctcgctgtg ccattacttc aattggcata catccttcaa
    17581 aatatttttc tttctcaaaa gatttaagtt ctgccacttc ggcattgatt agtgcctcat
    17641 ggaaagcttt gaattcctct tctgtcatcg gacagttcaa gtaagctgct tctcctttgt
    17701 catagcggga cttcaaatat actttatcca tatcgatcgt agctttgtct acgattggtg
    17761 cagctgcatc atagaaataa aaaccatctg aaccattgaa tgctttgatg ctttctgcta
    17821 atggatgaga agtcaaaggt cctgttgcta ctacggtgat tccttccggt atttcagtaa
    17881 tttcttcgtt tatcactgtt actaatggat gctctttgac ttttcgggta attgtttcag
    17941 aaaaagaatc gcggtcaaca gctaaggcac caccagctgg cactgctgtt tcatctgccg
    18001 aagtgattac taccgaattc aatcggcgca tttcttcttt caataaccct actgcattag
    18061 ccaaactgtt tcctcttaat gaattggaac atactagttc agcaaaatta cttgtgtgat
    18121 gcgcctcagt cgatttgact ggacgcattt catataaacg gacagggact cctgcttgtg
    18181 cgatctgcca agcagcttca cttccggcaa gccctgctcc aacaacattt accattttca
    18241 atgaaagaac ctcttttcta ttatttttgg atgtcttctt cgtaatctcc atttacacag
    18301 actacttgtt taccgccttt gactttcttc tcgaccagat atccgtcaca ttttggacaa
    18361 tttctgccca ctggtttatc ccaagaagtg aattcacatt ctgggaaacg ggaacaacca
    18421 tagaatagtc tgtttttctt agattttcgt tcaatgactt gtccttcatg acatactggg
    18481 caagtcacac cgatttcttt tacgattggt ttcgtattcc gacaatcagg aaaattactg
    18541 caagcataaa acttcccata tttccctaat tttatcacca tcggatgtcc acagacatca
    18601 caatcgaatc ctgctggttc atctttgatt tgaatttttt cgattttttc ttccgcattc
    18661 gtcagttctt tttcaaacgg tttatagaaa cgatcaacca ctttgaccca cgcttccgtg
    18721 ccttcttcaa ttttatccaa atctccttcc atttctgctg tgaaatggat atcgacgatt
    18781 tgagggaaga attcacagat taatgaattg acaatttctc ctagttcagt cggctcaaat
    18841 cttttttgtg tcaattttac atagtagcgt ctttggatcg tatcaagtgt tggtgcataa
    18901 gtggaaggtc gccctacccc gttttcttct agtgcacgaa tcaacgtagc ctcactaaaa
    18961 cgtgctggtg gttgagtaaa atgttgtttt ggttcaatat caacagattg gactacatcg
    19021 ccttcttcaa gttctggaag aatattttct ttctcttctt tgccgtcatc tctaccttcc
    19081 acatacactt gcatgaatcc tttgaatttg atttttgaac cgttcgcaat gaagatgaca
    19141 ccattttgtt ctaatgtcac tttcattgta tctaaaatag ctggtgtcat ctgactagcc
    19201 acaaaacgtg accagatcaa tgtataaagt ttcaattgat ctttatctaa atattgtttg
    19261 agttcatctg gtgtacgaag cacactcgtt ggacgcacag cttcatgggc atcttgtgcg
    19321 ccttgagcat ttttgatctt tcggtgacca tgtctagaaa attcttttcc atacgtatct
    19381 tcaataaatg ctgcggcctc tgcttttgct gtatcggcaa tccgggtaga atcagtacgc
    19441 atgtatgtaa tcaagccgac tgttccttgt ttacccaaag tgattccttc atataattgc
    19501 tgtgctacca tcatggtttt tcttgttcga aagtttaact tacgggcagc ttcttgttgc
    19561 aggctacttg tagtgaaagg attcgcaggg tttcttttgc gctctttctt ttctactttt
    19621 ttaacttcga agtctgttcc atcaattcta gcagtgactt cttttacact ttgtgcatct
    19681 ggtaatttct ttttcttacc gtcgattccc cagaaatttg ctttgaattt cttgcgagct
    19741 tttttaaaat taccgtcgat gctccaatat tcttctggaa caaattctcg gatctctttt
    19801 tcacggtcaa taataatttt taaagcgaca gattggacac gtcctgcact taaccctttc
    19861 ttgaccttac gccagagaat aggactgatc gaataaccaa cgattctgtc taaggtacga
    19921 cgagcttgct gtgcatctac taaatctaca tcgatcgttc ttggttcctt aaaagctgct
    19981 ttgactgcgt cttttgtgat ttcattgaag accacccgat ttttttcttt cagatccaac
    20041 ccaagtaggt acgctaaatg ccaagcaatc gcttctcctt ctctatccgg gtcacttgcc
    20101 aagtaaactt tttgagcttt ttttgctgcg gctttcaggc ttttgatgac atcgcctttt
    20161 ccgcgtatag aaatataatg gggttcataa ttgttttcaa aatcgatacc cattttactt
    20221 ttcggtaaat ctcttatatg gccaacactg gccattactt tatagtttcg tccaagatat
    20281 ttctcaattg tcttggcttt tgcaggtgat tctacaatca ctaaatattt atacgccatt
    20341 actgaatgga ctcctttcca ttgtcgtgtt cctactatta aaagaggatt catacaaatc
    20401 gtagctaatc atatccattc agaaaacgtt tgtcaagaaa agcaaatgaa aagtatggtg
    20461 ttattcttta aattctgcca agatatcttc acccgaaacc gtgcaaactg caccgtcttg
    20521 gatcaaatga tgacatccgg tagaatgttc tgttaaaata tttcctggaa cagaaaaaac
    20581 tgttcttcca agatccaatg cttgctgtgc tgttatcaga gagccgcttt ttttcttggc
    20641 ttcaaagaca catgttcctt tagacaaagc tgcgataatc cgatttctca ttggaaaaca
    20701 atgctttttc gggccggatt gaggaggata ttcactcaaa agaagatgat catttgcaat
    20761 cacctcttgc aagtcacgat tttcagcagg atagacttgc tctatccctg ttccaatgac
    20821 tgcgattgtc cgtccaccat gagagattgc tgcttggtga ccgtatgtat ctatcccttt
    20881 cgcgcagcca ctgacgatca catatccagc ttctatcact ggttttagta aataataaac
    20941 tgtttttttg gctaaagcag aagtgtgtct tccaccaaca acgcttaaca tgttacaaga
    21001 aagtaaagat agatcaccat tataaaacag tacaattggc ggataggtca agtgaagcag
    21061 ctgaggggga tatttgggat caaagcaagt gataaacgac tgtttcgatt ggattttgcc
    21121 ccagttagcg tgaatttcct gccaactttt gcgaaacagc tcccggtgtt tggttatttt
    21181 acctatctta atgatgtctt caaatccgat ttctttataa ggatactgca tcatccagtt
    21241 agcaagtgcc cattttcctt gactactgat tccttttgta taagcaagtt tcaataaatt
    21301 ttcttctatt tgatacatca taaaaccgcc tttcgtctct ctttctaata agatacgtaa
    21361 aagcggctgt tttttattgt aaatattttt ttacaggtgc aaaactttta cgatggattg
    21421 gcgtaattcc ttgtcgttca agtccttcta agtgttcctt tgttccataa cctgcattat
    21481 gcgagaaacc atatccagga taaagcacgt catattcttt catcaattgg tctcgatata
    21541 ctttagcaat gatacttgca gcagcaatcg acacagatcg tgcatcccct ttgattattt
    21601 tttcctgctg aataggcaaa tccaaggtca tcgcatcgat caacaaatag cttggtacaa
    21661 tggacaattt ttctactgct tggatcatcg ctaatttact tgcttcataa atattcacat
    21721 catcgattgt ctgctgatca acgatcccga tcccgattgc cagggctttt tcttgaactt
    21781 gttgataaag aagttctcgc tttttctctg ataattgttt ggagtcattc agccctaata
    21841 tgatctcatt tttcggcaag ataactgcag ctgccacgac aggtccagct aatggtcctc
    21901 ttcctacttc atcaatgccg gcaatccatt ggtgaccttg tgcgtaccct tgcttttcaa
    21961 agcaaaacat ttcttcatat ttttccttaa ttaatgcttc ctttttcaat cgtcgttcaa
    22021 aagaagccag tgcttgctgc acgcctttgc gtggatcatt tcttaatgat tctagtgtag
    22081 gatcatctat tctctgtatg cttttcaatc gttctttgat actttggatg gattcagtca
    22141 tcactttttt gctccatttc ttcgcaacga tccagtgtgt atcgtccaag ttttccttga
    22201 cgaatatcat gcacgactaa ttcgctgcca cgatcatagt cttctttata cccacgtttt
    22261 gctgtaatat ccatcagtaa ttccggtgcc aatttttctt cttgctcgat tgataaacca
    22321 taacgatcgc tgattcttcc tgaataatat cgggcaaaaa agtctaatcc gtaaatcgct
    22381 aaatcatcta aatggacaag ctggtctttg atcgcgcctg tcagcgctag ttttttgccg
    22441 atttcttcat cttcaaattt gggccataaa atccctggtg tgtctaacaa ttccaactca
    22501 ttacctaaac gaagccactg ctgacctttt gttacgccag gcttatttcc tgtctgtgca
    22561 attttcttgc ctactagtcg attcatcaac gtagatttcc caacatttgg aatacctaag
    22621 accattgccc gaatagcgcg aggcttgatc ccccgagcag catctcttgc ccgtttttct
    22681 ttcaatgctt ctttagccgc aggtactaga cctttaattc ctttactttc ttgtgccgtg
    22741 atagctaatg caagatggcc ttgtttacga aaatattctt gccacagctt tgtctgttgt
    22801 ggatctgcca gatccgcttt attcaataaa acaaggcgag gtttttgctg aatgatctga
    22861 tctagcattg gattacgaga agataaaggt aatcgtgcgt ctaccaattc aaatacgatg
    22921 tccacatatt tcattttttc agaaacttct cgtcgggctt ttgccatatg tcccggaaac
    22981 cattggatgg tcattgttct ctccattcct ttcataccgg aatattcccc ggctttactt
    23041 gtttttttct ttttcaatat aaattcactt ttttattatc ttaattgtca aattaagtta
    23101 gacaaatcat caatacttac gtaactcaaa aatacttcca aaggtgttcg ataattcagt
    23161 gattttctag gaatattatt tcgtttcgat gcgacagatt gaataaaaga ttcatctact
    23221 gaattgaaat ccatagattt caataaacca tctctacgta acaatccgtt agaattctcg
    23281 tttaggcctc tttgagacgg cgttcctgga tcagcgaaat aaatggcaat atcattggca
    23341 ttactgatct gtttccaatt tgaaaattcc tttccacaat caaaagtgat ggatttgaat
    23401 agatttttcg gtacagattc aaaccaatga tttaatttgt tttcaatatc aatcgcttgt
    23461 ctaccacacg gtttcaatgt gatgataact tttgataatc gctcaactaa ggtaattaca
    23521 gcacttttat gtttcaaacc tacgatagtg tcaccttcaa ggtgaccaaa ctcatttgag
    23581 aattggctat aatctttttc acgttcatga atagagcgac ggaaagcttg ttttccacgt
    23641 ctttcttgat gtccatttgg tttacgcttg cctttcatcg gtaagtcaga aggattaaat
    23701 agcccctttt tgaacatacg ataaatggta cgagcagaac aacgaatagg aaacgctgca
    23761 cgaccaacaa tcacatcggg tgtccatcct tgaacaacct ttctttgaat atattctgat
    23821 tgttcctcag gtaaaacaag cgggcgtcta ccacagtttg atttgttttt cttatactgt
    23881 tgatagtact ctaaggctga ttttccttgc ttgaagaaca ggtatacttt atggatcgtt
    23941 tgtcttgaac gattcaagaa atgcgcagtt ttcgcaacag attgatttat tttgaaataa
    24001 gactctatca ttacaagttc atccgttgta agatgggtat aggtcatttg tactcactcc
    24061 ttataattct ttggacggaa ctattttgag tgtagcacaa atgacttttt tagttgtcta
    24121 gcttaatttt acaatcggcg ttataaagaa attccatcta ttagttaagt gaaagtgaac
    24181 cagtcctcat tctatcacat cttcactttt ttgatgatgc aaatttttat tttggtttct
    24241 atatatgaat ctaaattttt gacagcgttt cctaaataag agatgataga cgaacaaaac
    24301 agaaaggaga cgaaacaaat gaatagtatg gtttttgtta attttcctgt tgctgatgtc
    24361 aatcgttccg ttgcttttta tgaaaagctg ggttttaaaa aaaatgaaga attttctact
    24421 gaagaagctg gttcaatggt atgggatgac actttttgga taatgcttct ctctcatgat
    24481 ttttataaaa aatttataaa agataaagaa atagctgata ataaaaaaac aagtggtgct
    24541 ttgatttcgt ttagtgttga aaatgcggat gaagtaaaaa aatttgctca aattgcaaaa
    24601 gaaaatggtg gtactttcca cgaagtagat atgggaatgc ctgaagaaga aatgttttca
    24661 ttagaagtcc aagatctaga cggaaataca ttagaacccg tatggatgaa gatgtaagca
    24721 gataactaat ctgacgtttt ttataacaaa aaaacaaagg cggatgatac gataagtatt
    24781 ctccgcctct atttttttta ttcgtacaat ctctttttta cagtttataa aagcagtctt
    24841 ctcacccttt ttttaattgt tagatgccag tgtatgtaaa tcaccaatgt gtcatgacac
    24901 attggtgatt ttatggtatc cttttattat taactgacaa aggagagaat attttgaaca
    24961 ctttgattgc aaaagacgtt tttagattgc ccgaaatgaa tgcaagattg ttgtcgacct
    25021 ctgctctttt attagccctt gatgtcatct tatacaagat agcgattggt cctgcttatt
    25081 ttcaaatcac attcggattt ttaagtatgg cgcttatggg ttatctatat ggaccgatct
    25141 gggctggttt gcttgaaatg ttgtcgaaca ctttaaattt cacgatattt ggttcaggaa
    25201 cgtttcaagc tgcttttctt atcacggctt tccttggtgg atttattaat ggcttatttt
    25261 tatatcataa aaagataaac ctgccttccg tcatcgctgc ccaattattg attatgatcc
    25321 cagtcagcct ttttatcaat tcttggctga tgtctgtttt gtttggtgca gatttcaaag
    25381 taatttttct aggtagattc atcaggaata tgatccaaat ccctattcaa ataatggttg
    25441 tttattcatt tatcaaaact ttagaggcta gaaaagtgtt taaacgagct gtttgatttt
    25501 acgtactaag gtagtaaact gattttggat taaacaataa agcgtgcagt ctcaacagac
    25561 tgcacgcttt attgtttctc actggatcca ttttatttca tcaagtggat aatagacaaa
    25621 tcttgcttta cctagaatat cagttttatt gatcgtgcca aacgaacgac tatcttttga
    25681 aactcttcga ttatctccaa gtacaaaata attatcttcc ggaagcttgg attgtcccgt
    25741 tagctcttgt agtgtaaagt ccgtcgtata ggatgcattt gcatgatctg atttcaggtt
    25801 tttagttaga taaggttcct taactacttt cccattgatc ttcaattgat cattttggta
    25861 gctgacattt tctcctggaa gaccgattac tcgtttgata taaatcgtgc catctgctaa
    25921 ttgaaaaaca acaatatcaa atcgtctgat ctccgaaaat ttttccatca caaccatatc
    25981 accttgcttc aacacgtttt ccattgaatt gccttccact ggtaccggga tgaataaaaa
    26041 tccccgcaac atgaacgcaa ggaatacaga aacaagtaag tatttgaata caagccagaa
    26101 gcgattaata tagcgttgtt tttttgtcaa tctctatcaa tccatccctc tttttttcat
    26161 tctttcttta ttataagaaa aatatcaaaa aaatgcgact agatagctga aataaaaata
    26221 attctttcaa ttaggctatt ggacaaaaaa cttttttgat cataaagtac aaaactatct
    26281 cttatatgtc atgattattt tctaaatatt tttcccatgc ttcgtcaaag atatccatgg
    26341 acggcaaata gtcgacattc agttccagat aattagaaat ttcttcgtag ctagagctgt
    26401 gcttaggaaa ttggatgtct ttaccggctt ctgtagcgaa aacagataaa gcatcatgtg
    26461 tgccaccgcc tcgcagtgtc attaaataat gaaaaaagct tcgattcacc cttcgttcct
    26521 ccaattttct tcgataaagg cagcccggcg tgcatggttt cttttaaaat tttcaggatg
    26581 ctttttataa tactcttgat ggtcttcttc tgctagataa aatggttggg ctggttcgat
    26641 ttttgtaacg attggctgtt cgaaacgtcc actttcagct aactgtttct tacttttttc
    26701 agcaatgatc cgctgttctt ctgtcaaata aaagatcacc gggcgataat tgtcaccgcg
    26761 atcctcgaat tgtccgaaag cgtcagttgg atcagtttgc tgccagtaaa gttctactaa
    26821 ttgttcatat gaaatcaatg ttggatcata gataatctcc actgcttctg tatgtccagt
    26881 cgtttggctt tttacttgtt cataagtcgg atctggtaca tgccctccag tatatcctga
    26941 catcactgta tggataccag gaagcgtgtc gaaaggctgg atcatacacc agaagcagcc
    27001 tcctgcaaat attgctcgtt ccattatgat tccccctcta atactactca tccgatgatt
    27061 ttttattttc ttttgtcttg ctttcagtac tgctggtgct agttttgttg gtatttgagt
    27121 tgtttgaagc atcagaggta tcttttggca aatatagact aaaccgaatg tcatcattta
    27181 ctaagtcgat tttatctgct ttaatataca tcccgttttg cattcggaat tgatccaacc
    27241 taagcatgat agtcagatca tctgtattga cttcgatcca atctggtaat ttatagtttc
    27301 tcttgatcat attcatcaca tctttgattg gcaaactcaa tgttccgata gaaagacttc
    27361 tagcttttag ttggacattt ccgttttcca tcacatacgg atcaaaatat aaatagaaat
    27421 cgataggaaa acctagtact tcgaaagtac cattgagtag tgcttcattt tccaaataaa
    27481 atttatattc aatatcacta tctttttgat actcactaag gaaaaagctg atgatttgat
    27541 tgactttttc tttatttgaa ttgatcgtta agacaggatc tccttgtctt tccgtaagag
    27601 ctggtatttc tgggagttct ggttcccgat tagcaaaaat acggctgcct aaaaatacgg
    27661 tcgaaccaag tactacccca agaaggataa ggaaggcgaa tttccagtaa tttgttttct
    27721 ttgttttgtt tgaagatacg tcagatcttg ttttcatgtt tattgatcat cctccttctc
    27781 taaccattgg ttttgtgtct cgatcagctg atctctcact gcatttgcca tcaattgata
    27841 acctaaatta tttggatgga aatgatcttc ttcatagagc acattatttt tgatgccatt
    27901 tagattttct gtcgtgctag ttgtttgatc tgttccttct tctgtgacac ctacttcctg
    27961 attcaatcct tgataaagca aatcattgat tgggataaag tagcagttcg gcattttttt
    28021 tgtcaccgtt tctgttcctt tgttccaatt gttaacaatt gtctgcatgt cagtgatctc
    28081 aggaaagttc aaataaaatg gattgtagat gcctaaaatg taaataggtg cggttttatt
    28141 gagggatcga aattcttcca atagttctgt gacattttcc tgatagtttt tcagtggctt
    28201 tttaaaggaa ttgaccgtta acccgaataa attattttgg ataactttca tcaaatcatt
    28261 accgccaaca gtcagtgtga taaaatcagc tgttttgata ttgtttcgaa tttcttcttt
    28321 tgtttttact cgctttaaga tctggtcact tcgttcacca tttacaccat agttttctgt
    28381 ttcaaccgcg gtcaaattat aacggtcttt tagatcattt gcgacaaggg gaacgaatcc
    28441 tccttgcttg gtttgatctc ctactccttc agtcagcgaa tctccgatag ctatgtagtg
    28501 aagtttttct tttttatttg gatcttctct cacagtagtt actggtttca ttagtgggcc
    28561 agctttcggt atagaagcag ctaaacctgc atagatgatg atcgcaatta ataatgggaa
    28621 caaaacgagg atcaaatgtc gtttcgttaa tttcattttt tcacctcttg tattcgattg
    28681 gttctaatgt tatcaaaaat tttatcaaaa aggtagtctt tatgaaaaaa gaaaacaatt
    28741 attttcctaa ttttataaag aaaaagagaa taagctgcaa gcctttcagg ctgagggctt
    28801 atcctctttt cgactaatct acataataca tgattgcaaa cgcgtcttta ccagtatgcg
    28861 tagcgataac cggattcgta tgcagtacag ggatatgcat gtccgggaat aattcttgca
    28921 aaccctcttt gaattcttgc gccaattctt ttgcatccgc atgtgaaata ccgatttgtc
    28981 gcacatttgg caattctttc agttcatttt tcaaattatt aaaccattta tcgaacgttt
    29041 tctttcctcg ccccttagtt acagggatta attcagaatg ggcgaaattc atcaccacgc
    29101 gtatgttcaa aacactagac agcaaaccag ttgttcggct gattcttcca ccttttacca
    29161 agttatctag tgtggatatt ccgatgtata attttgtatt gtcttgtact tttttgactt
    29221 cttcaaggat tttctctact gttttacctt cttttgctaa ttcagctgct cgaattacct
    29281 gaaaagataa tccttggtca gtggtatcac tgtcgataac cgttactttc gtttttgtta
    29341 gattactggc ttgtcttgct gcttctactg ttccactcaa gccttttgtc atatggatcg
    29401 aaatcacttc actgccgtct tctcctagct catcatacat cgagatgaat tctccaattg
    29461 gtggttggct tgttttgggc agattttttg ctttcgccat catttccata aatctttcgc
    29521 cgtctagttg gtcatcatcg ggatatactg ttccgtcgat catgatggat agcggcatga
    29581 cacgaatgcc taaagcatcg cgtacatttt tttccatcgt acatgaagaa tctgttacga
    29641 tttttacatt tgtcattatt ttctctctct ctttctttaa caagatgcct tattcatgtt
    29701 aaactacatg taagacaatt tctattttta gtataacaga caaataatga tttttcatta
    29761 attacaccta gtaaaggagc cgttttcatg gaaaaaacga aatttaatcg aacgtatgaa
    29821 atattaaatg aagtgtttaa tgcagtcacc catggaattg ggactggatt gagtatcgcg
    29881 ggactagtgg ttcttttagt aaaaggtgcc cacttgcatt cctccctcca tattgtctct
    29941 tatgctatct atggatcgat gatgattctt ttatttttaa cgtctacttt gtttcattca
    30001 ttgattttta caaaagcaaa aaaggtgttc caagtattcg atcatagttc gatttttctt
    30061 ttgattgcag gaagttatac tcctttttgt ttgctgagta tccgaggatg gctaggttgg
    30121 actttatttg tattaatctg gttgtttgcg attcttggca ttatatataa agcgttgacg
    30181 ttgcataaac gggagagagt atcaaaagta tctacgatca tctatatttt tatggggtgg
    30241 ctctgtgtcg tggctgctgt tcctctttat cactctcttg gaatgactgg tgttattttg
    30301 atggtagcag gcgggctttc ttacacgata ggcgcattct tttatagctt gaattctatc
    30361 cgctatatgc atgttgtttg gcatttgttt gttatgttag gtgcaggttt tatgtacttc
    30421 tctgttttat tctttactta ataaaaaaaa taaagctatg gatgggacag ctctaaataa
    30481 cagctagtct atccatagct tttttatatc gtcaattcgc ctgtcccgct ttttacagga
    30541 ttctcattac gctgatacgt ttcaaattga tgcggataac gatttttttc atccatttct
    30601 ccttgactag tattgatcag tgaccaatca gaccagtcaa caggtggaaa ataagcatct
    30661 ccatcgaata catgatggat gactgtacgg tataatatcg tacaaaatgg cagaaattct
    30721 tgataaacag ctgaccctcc agcgatgaaa aagataccgt ctgtttcttt ttccagagca
    30781 agcacgtctt ccacactatg catgacatgc acgccttctg ctttatagga agaatctctc
    30841 gtcaaaacaa tcgtctgacg attcggcaac ggacggctac ccatcccttc gaatgttttt
    30901 cgtcccatca ctagtgtatt tgcttctgtc atttgtttga agaatttcag atcatttggc
    30961 aaacgccaag gaagacggtc ttcttttcca atcaatccgt tttcatcctg tgcccaaatt
    31021 gcagctaaca ttttctcatc ctttctgatt ctaaacagcg ataggagctt tgatcgccgg
    31081 atgtgggtca tatccttcta attggatatc ttccatctca aaatcaaata ctgactgctt
    31141 ttcctgattc aaaactaaag tcggaaatgc gcgtatttct cggctcaatt gttctttcat
    31201 ttgttcgata tgattgatat aaagatgagc atctcctaat gtgtgaacaa attcgccaac
    31261 cgctaaacct gtttcatgtg caattaggtg agtcagcaac gcataacttg caatgttgaa
    31321 cggaacgcct agaaacacat ccccactgcg ttgatacaat tggcagctta gccgtccctc
    31381 ttgaacataa aattgaaaca tcgtatgaca aggaggcaaa gccatgctag gaacatcttc
    31441 cggattccat gcagaaacga tcaatcttct agaatcagga gtctttttga ttgcttcgat
    31501 cacttgtttg atttgatcga taaagccacc gtcttttgtt tcccagtgac gccattgata
    31561 gccgtagatg tgtccaagat cgccgtatgt ttcagcaaag gaatcatcgg ttaggatctt
    31621 ctcgcaaaaa agcttgctct gctttttata ttcttcattg aattcaggat ctgtcaaaca
    31681 tctatggcca aaatcagtca tatctggtcc attatagtct ggacttttga tgtagcgttc
    31741 aaatgcccat tcatcccaaa tatggttttt attttgtaat agatagcgga tattcgtatc
    31801 tccttttaaa aaccaaagca attcgctttt gatcaatcca aaaggtactc gtttcgttgt
    31861 taacaaagga aacccttttt gcagatcaaa ccgcatttgg tatccgaata agcttaatgt
    31921 gcctgtgcct gttctgtctt ctttacgatg cccttcttcc aacaattttc ttcctaagtc
    31981 aagatacgct tgttccatcc tttttcctcc taatcttcta cccattcact caagtattcc
    32041 caccgtgcca ttttttcttc aagttgtgct tctgtttcag atacgtcgtt ttgcaattct
    32101 tgtaatcgag tgaaattatc tccttgatga ttcatctctt cttggagcaa tgagattttt
    32161 tcttcaagtt ctgcaatctc atcttcaatc gtttcccatt ctttttgttc catgtaagat
    32221 aatttcttct tttcagcagg ttccttgctc tgtatttttg gtttcgcttt ttcagcaggc
    32281 tgctgggtct ctttttgctt cagtaaataa ctggacatgt ttccgtaata aagttcttgt
    32341 tttccgtttc cttggaatac taataactta tctgctacct tgtccaagaa ataacggtca
    32401 tgggaaacag tgatcacagc acctggaaaa cttctaaaat aatcttccaa aatcgtcaat
    32461 gttgctatgt ccaaatcatt ggtcggttca tccaataata aaacattagg ttgctgaatc
    32521 agcagtttca acaaaaataa ccggcgtttt tctccgcctg aaagtttgcc tatcagtgtc
    32581 ccatgcataa atcttggaaa taaaaatcgt tcaagtaatt ctgctactcc gatttgactg
    32641 ccatctgctg tttttgcttc ttcagcagct tcttgtaagt aagcaatcat ccgtttatct
    32701 ggtgccattt cttcattttc ttgtgtataa tacgcaagat gaaccgtttc accgatagac
    32761 attgtaccgc tatccagggg aattctgcca gctagaatat taagcaatgt cgattttccc
    32821 gcaccatttt taccagtaat acctagtctt tcccgagatt gaatcaataa atctaaatgt
    32881 tctagcagtg tttggtcatt tatacggtaa ctgccatctt tgatttccag tacttttttc
    32941 cctaaacgtt gtgtcgctag gttcagctct aaatcatctt cttggtttac ttggtacaag
    33001 ttctccttta gatcttcgaa acggttgatc cgtgcttgct gcttggtgcc acgtgcctgt
    33061 acgccagccc tcatccaagc taattcctgt ttataaagcc gcttgcgctt ttcttcttgt
    33121 tctacttcta cacgatcacg ttctgctttt tctaagacgt aagcttcata atttccttta
    33181 tactcgtata attttccaaa tgaaagttcg aagattcggt ttgctactct atctagaaaa
    33241 taacgatcgt gggtaaccat caatagtgcg ccacggtatt gtttcaaata gttttccaac
    33301 cactcgatcg cttcataatc taaatggttt gttggttcgt ctagtaatag taaatcgggt
    33361 tcatcaatca acacttgcgc cagactaact cgttttttct gaccacctga taaagtactg
    33421 atttttttat ctaattcact gattcctaat ttttgcaaaa taatctttgc gttggtatct
    33481 gtagtccaag catcttcttt attcatttgt tcttctgctt tagcataacg tttttgcaca
    33541 tcagggtctt ctccgttttc ccctagttcg atcaatgctt cctcatatgc tcgaacagtt
    33601 tggatcaagg ggctgtttcc ttgaaagact gcttggagaa cagttaattc atcggaaaat
    33661 tcagctgctt gagaaagata accaatacgg taatcagttg gataaaacac tgtttgccga
    33721 tcaccgtcgc tgctatcgat accggcaata atatttaaga gacttgtttt acccgtcccg
    33781 ttcgtcccaa tcaacccgat acggtctttt tcgtggacca aaaaagaaat ctggtcaaac
    33841 aaatcttttt caccataagt ttttttgagg tcagttactt ttaattcttt caacatgttc
    33901 cctccttatc ttggatattg tatcataaaa atagtgaact tcaggaaaat ttttttggta
    33961 tttgttcttt ttgtgttctc aaaaaaagaa caggaccgat tcgatcctgt tctgatatgt
    34021 tttgtttttt ataaaacttg aaaattttta cctttttatt ttattggact cgtttttttt
    34081 gactttgctc gaaacgcaaa tcggaaagaa aagttatcag atggtttgtt catcgtataa
    34141 gattctaaca aattgatatt cctgcgatag ctgttcgcag aaaacgtcgt gattttttca
    34201 gcaacttcgt attcatcaat gatttttctt tcaagataat aacctcttag catttttttc
    34261 gtaaacagac tatcttgctg gatcatccac gaagaaatca aattccccga gttcattttt
    34321 attccttcaa gtttgcgttg ctggataaaa aattgaacca tcgtttcatc ataaatatca
    34381 gtcaagttat ctaaactttc aataatcaac tgagtatttt tttgatatgt ctctctgatt
    34441 tcttggatat cttcatcact aataaatgtc tgacgatcag catatcttct ttgccaaaac
    34501 attttcggat ggagaacgat tcgcattaac ctacggacaa caatgaacca aaagccgata
    34561 aaagacaaaa tctggcttgt gatagaatgt tcgaatcgag aaagaaaacg ggagtaaaaa
    34621 cgataaccat tagaagaaag cttgcccgaa cgataacttt catccaatcc atcccgttcg
    34681 atcgacaaaa tcagtgcttg tatttcttgt acttcttgct tttcatcatc ggttaaatct
    34741 tccaagtaca gatcacgtat ccgttcttga taattttcta tcactgcttc agtggctaaa
    34801 aattcttttg tattacgatc aatttccttt atttcttttc gcaaaacttc aacgacctct
    34861 tctaaaatca tcaaagcatt caaatccgtg cttttcgctt cctctgtttc cgtcagcata
    34921 ggcaagacaa tgatccctat gaccaaagtc actaagatga cacccgccgt cagaaacaaa
    34981 agcaaagacc gctggtaaaa catcatatta ttgattgaaa atggcaaaat aaaaatcgta
    35041 gccaaactga ctgttccctt tacaccgcca aatgttaaga tcaagatctc gttcaactgt
    35101 tttttgaact ttttactgcc atctttgaat acataaaaaa gactgataga aatgaatctg
    35161 atcacaaaaa gcatgacaga gattaatacg ataatcgcta ataaaagacc gtttggatat
    35221 aaaccgtctc cccatactgg cgagaacact tgcgtcaatt cgattcctaa aaatataaat
    35281 actaatgcat tcagtgtaaa agcaatagtt gtccatgtac tgtgggacaa gctcgacaat
    35341 tctgcatcaa acacagagat tttcctaaaa ccagaagctt ggagaatacc tgctgccact
    35401 gcagcaatga ttccagatac atcaaatgcc tctgccaata cataggctag aaaaggaagc
    35461 aaaagttcga tcagcagata ccctgtgaca tcttgtgctg atgctttttc gatcaaatga
    35521 attatttttt gtttgaacca gacaagcaaa aagccgatca aagctccccc aatactagaa
    35581 actactagac tcatccccgc gtttactgct gaaaaagatc cggtgatcag cgcaccaaga
    35641 gcaaactgga aggcagtaac accagatgca tcattcaaaa gaccttctcc ttccaaaata
    35701 tgcatcgcct ttttagggat attcactcgt ccagaaagag aactgactgc taccgcatct
    35761 gtcggaccta acgctgctcc aaaagcaaag caggcagcaa gtgggacact tggcaacagg
    35821 aatgataacg tcgcacctac cccgacaagg gtcaaaatga ctcctccaaa tgccaagaac
    35881 aaaattgtcc cgaaattttt gagaatcgaa gaaatatctg ctttttctcc ttctctaaat
    35941 aacaatggtg caataatcat aactaagaac aattcaggtt caaaatcgat tgattgtccc
    36001 cactctgtca gacctaatac cactccaagg aaaatttgga tcagtggagc tggaatcatt
    36061 ggcaaaatgc ggctagctat gttcgataag gtgatcgtta ctgcaaatac aataactaac
    36121 tcagcaaatt ccatcgtcca tcccctttat tttttatttt gtgtaagcat ttttaaaaat
    36181 tgttcttttt tctttaaaat tttggtttcg actacttcaa cctgtgtttg gttcccctct
    36241 aattcacact gtacacgttt tgactccaaa cgaagcagat catgtttcag acgttccaac
    36301 tgacgataca tcaatatatt tcttttacgc aacttacaaa gtatttgacg gcggtcatcc
    36361 atcgaaaggg cgccatagcg atcatgcaac agtttttttt gttgttcaaa actctctctc
    36421 attttccaga tctcctatac acaaacttcc atcattatag caaagttctt tttggatgaa
    36481 aaatatttca ttgtttcatc gtttattgct agttagaaat ttccataaat ttttcaacgc
    36541 ctcattctat tccaaatagt atcagatatc aagtaaaact taagaaagat aaaagtttct
    36601 gacaaaagga tgtttacttt cccattcctg cctttcttgt tcttttatca caacaaaaaa
    36661 atggggctgc gacaaaaatc ttgtcacagt cccttattct gaataaacgg tgtggaagag
    36721 acagcctatc agtagtaata agacacatct ctttcacagc ctcatttttg cgtaaaaatc
    36781 gatttattcg aaaaattccc cgtatacatc ttctacacgt tgatctggat tgatcacgat
    36841 atacaagtta cctgtttttt cgctgatttt tgttgattga tattgattgt ctaatccttc
    36901 tgttccttta tctagatatg ggaagtacac aagatcaggt gtgccatttc ggtaaaggat
    36961 ttccattcgc tcgatatctt cgtatttcaa tgcgcgatta aacatgccca tttccagtcc
    37021 gcctaggttg atatcatgtg tcgcaactgc gtccccttca tggaagattt cgattttaaa
    37081 tccagcacac ggatggattt caacaaattc actgccattg attcgtccaa aacttgttgt
    37141 gatttgtttg atccaaagat cgccgatatg acggcggttg atcgtccagg tttctccatt
    37201 tctaaaataa aattttagcg ctgtcatttc tttactcatt aaaaagactc ctttatgatg
    37261 taatttattc ttgtactacc tcagtttagc acaaatttat gtaagtggtc acatcttatg
    37321 ttttttcttc taatgacgta tctgcccact ttaagtagcc aacaaagctg agcagataca
    37381 gtctagtgtt ttttaaatca atttttcttt cgataaaaaa tccaaaacct gttttttatc
    37441 attttttatt ctttgttcta cgacggcttt ttcagctaat tgcaaagctt cactaaccca
    37501 cttaccaggt ttttttccag tttcttctag caagatttta ccatctactg ctaattcgct
    37561 taatgacttg ataggtaaac gatcatagga ttctcctacg gcatccatct gaggtgtttc
    37621 gtcaaaatag atcatcaatt cttctacttg cagtgcatgt tttttgccta agaagtacaa
    37681 ttcgaatggt tccaaagctc cagtttctcg ttgtcgtagt ccttggacaa gtgcttgaac
    37741 gtctttaatc atttggttag aacacttcca cgatttcaaa aaggaacgaa tctcattttc
    37801 ttttagatcc agttggctga tcaataatgc ccatgcttgg ctctcttctt tcaatgggac
    37861 ggatggtaat tcagcaaaac gtaaaagtgc ttcgccttct tctttcaaac cgggacagca
    37921 aatgtagcac tctgtttcaa taaatgcatg gattcccgcg gcccgttcat ttcccaagag
    37981 catcttgatg aattccacat ttatacgttc tacagatatt ttacctaata gctcgtggtt
    38041 ttctttgatg gcgtagaagg tttcttcctc taatttgaac cctagttgac tgacaaaacg
    38101 caacccgcgc atcattcgta aggcatcttc atggaaccgc tcatgaggat tgcctacagc
    38161 tcgcaagatc tgttcttcta gatcttgcag accatcgaac aaatcgatga tttctccatc
    38221 ttctttcaaa gcaaacgcat tgatcgtaaa atctcttctt ttcaaatctt ctgccaacga
    38281 acgaacgaat tcgacatgat ctggtctacg gtagtcctga taagttgatt ccgtccgaaa
    38341 tgtggtgatc tcatattgtt catcattttc taataccaac acagttccat gttcgatccc
    38401 aatatctatc gtttttggaa aaagctgttt gatttcttct ggaaatgcgc ttgttgcgat
    38461 atccacatca tggattggct ggttcagcaa gatatcacga acacttccac ctacaaaata
    38521 agcttcatat cctgcattct ctaatttttt cagaactgga attgcctttt ggtattccag
    38581 aggtaattgt tttaatttca tttttccaac ctttcctgcg tgtttcttgt cctgagataa
    38641 agactcagtt gcatggtgac tgtttgacaa gtccgtttca gagtcttcaa ggccaggacc
    38701 acttcatctt gtttactcgt ccttacgctc aaagcgatta tggtctcttt gattgaattt
    38761 ttccatgttt ttttcaaaaa cttcagttaa gtcgatattc aatgaattag ccatgatcat
    38821 cgtaacgaat aaaacatcac caagttcttc tgctaccgag ttaactggtt cagaagcctt
    38881 tttgcttttt tctccataag tgtggttgac ttctcttgcc aattcaccta cttcttcagt
    38941 taatcgagcc atctgagcta atggagagaa ataccccacc ttgaattgct ggatatattc
    39001 atccacttcc tgctgcatac tgtataaaga acgcttttta tccatctttt tccctccaaa
    39061 actatcttac caaaacttta acgcaaatcc tagataagag caattgagaa aatcgaattt
    39121 ccatgctaca tttaggaagg aatttctaaa tggaaattct gtgaaaatac ataattgaaa
    39181 gctggaattc atatggtcaa acgaaaaaca gtaaaagaag ttctttttat cattatagga
    39241 acaagtattt atgcatttgg tcttgtttac ttgaacatcg ctaatcattt agcagaaggg
    39301 ggagtctcag ggatcacctt gatcttaaga gctttatttg gtattgatcc agcttatacg
    39361 actttattaa tcaacatccc attgatttta ctaggaggaa agatcctcgg taaacgttcc
    39421 ttggcctata ctgttctagg tacactttct ttgtcattct ttttatggat ctggcaaagg
    39481 gttccactag aaatcaattt acagcatgat ctactgatcg tttctctact tgcgggttta
    39541 gttgcaggtg taggaagcgg gatcgtctac cgcatgggtg gaacaacagg cggcagtgat
    39601 attatcgctc ggattttaga acaaaattac ggcatcacta tggggcgttc cctattggca
    39661 tttgatatca tcgtcttact tgcttcatta acctatatcg acttgaaacg tatgatgtat
    39721 acgttgattg tttcgtatgt tttcagtcgt gtgattgatt cgatcttaga tggcggatat
    39781 tctgcaaaag gtctacttgt cgtctccaac aaaagcgaag agattgcacc actactgatg
    39841 accggtctgc aaagaggtgt gactttcctt tctggagaag gcgcattctc tggtaattca
    39901 aaaaaaatca tctatatggt cgttagctct agtgaattaa ctgaagctaa gaggatcgtc
    39961 cacgagattg acgaaaaagc tttcctttca atcatcaatg tgcatgaagt ggaagggcaa
    40021 ggctttactt atttgaagcc acagacaaga ttactgaaaa aactataaga aaaaagacaa
    40081 agataggcta tgaggaaaga ttccacatcc agctgacctt tgtctttttt agtactatac
    40141 tatttttaac taattgttat gttcacttac ccggttactt ttcttttgtg tctgcaaaag
    40201 gatctttcgg ttaacttcat cagataattt caaaaaagca tccctatctc catcttctag
    40261 tgcttgatcg atttgagcat aaagcatttt tagttttgcc tcttcttctt tttcttgaaa
    40321 atatcgttca attaattcag tatcttcttc actgactgaa gaatcccaag aagaaaatgg
    40381 attgtcttct aagatagata gatattctct tgtctgccaa gcattttcga atatacattc
    40441 cacatataaa ggctttttcc aattcaaacg gatttcatga aaaatctggt ctgtgtccgt
    40501 aaattctttt ccctgcaaaa acaatttcat gggttcccct tcaacagata gatcactgat
    40561 ctgcagtcct cgatccgcaa aattcgcccc ttcaacaaag tggacattgc ttaaaatcgc
    40621 ttcatgattg gcaagataat tcaagatcca aaaaacttct cttcggctaa aagatacatg
    40681 attgaccatc cacgttaaaa aattcttctt ttcccgtaca tcaattagca tttttctcac
    40741 ctctctgtta ggtcatctaa taatgacagt gcctccatat ctcctggttc aagtgttaaa
    40801 taataagtca ataattcttg cgctcttttc agctgccctt cttctcttaa gaaaaaggca
    40861 tactctttca agaaatctgg ttcatgtgat agttcatgat aagcctgttc atagtgtaca
    40921 gctgcaacgg taaagtcttc taattcatta taagcatggg ctaggttcca ttctgcataa
    40981 ggattagcag tttcttccat ctgattgatc acttgtatca catcttcata tctttcatca
    41041 tccaagtaaa gattacttaa agtaagtaat gtttcatctt gtttgtctcc tacttctaaa
    41101 gctttcagta aaagttcttc tgctcgctgt ctatcatgca gacggaaagc attttccgag
    41161 gccaggtgat aaagttcgac ttggtaagga ttttctttga ttccttcttc taacactgtt
    41221 tgtgcttctt caatcatttc ttcttcttga agagcttgtc ctagatatag atataacgat
    41281 tgataatgcg gattaacttc tcgaagttct tccagatagt tgattgcctg ctgattttct
    41341 ttcaattgaa gattcgtaaa agctagctgg aacagtcgat catctgtcct ttcttctttc
    41401 agtgcttctt ctaaaggtac gatagctgct tcgaattctc cttgcatact taaggattgt
    41461 cctaaacgtt cctgcatcga gattcctgaa atttcattta tcccgcttgc caacaatgtt
    41521 tcataaacca ctgctgcctc tttgaaacga tcaactgaaa aatacaattc agctagcgca
    41581 aactggatca atggttcatc aggaagcaac ccagctgctt ctttcaattt tgcttcactc
    41641 acttcaggga ttccgataac ttggtacaaa tcagctatcg ccaataagct ttgcggatag
    41701 taatcacttt gcttatccac tttttccagg tattcaaaag ctaagtcgat ctcattatct
    41761 tcgattgcaa tttctgctaa cgggatgttc agtccgtcat tttctgggta ttggttgatc
    41821 agttgttcaa aaatctgttt tgcttcgatc aaaaagccaa tagccagcaa ttcttcgcct
    41881 agttcagcta atatatctgc tgggtcttct tttaatgctt tttctaaaaa gatttgtgct
    41941 tgtgacaagt cttcatctga taaagcttgc aacatttttt cgctatttgt attcatttca
    42001 attccctctt atctcactga cgatttgttg aaataccgtc attgttctca ataattcttt
    42061 ttcgtttgga tgttggtatc cgtctattat acctattttt tctaaaacaa gtattttttt
    42121 gcttttttct gccaaaaaaa gaactttttc caaatactcc atctttgaaa tctgttccag
    42181 ccagtggatt ggatagccaa gcaagtccag ccacacaaaa aagtttttta gttggaaatc
    42241 aaaaggatat gcttggagat tccacacgaa atgaaacatc attcctaaaa attttttcat
    42301 actagcagaa agtagatggc cattttcggt cagataaaaa gcttgttcaa acagtttacc
    42361 ataatttgac aggttttctg cctctaattg ataaaaatag atcatttctt cgatcatccc
    42421 ggcaaacggc cgagtcgtta attgcttttt atttggatag tttttataca gattttgcaa
    42481 aaaacgatga tcacaaatca ttccgcaaca gataaaagtc aaaaagtcaa tctgctttcc
    42541 gtccacctgc cgctcgctga ttgtttgatc ataaacgatg cgttctggca gattgatggt
    42601 ttgcagcact acacgatttg gtagctgcaa aatcgtccgc tgcggtgtta atgctcggct
    42661 tagagaacgg atcgatacag ggatcatcca tagtgatgaa tcaagggttg tatgtttttg
    42721 aaaaaaacct gccagatcca tgatcccttc atttccaaat ccgatgataa acatggattg
    42781 attttcggga tagcgtttga cgaaatcaag caggttcttt aattctgtta aatgattgca
    42841 ttgagtgttg gcacaaatat accagtcatt gtttgcttga tttgcaaata acgggttgat
    42901 cttatctgca aacaaatcat aatagcgctg attcgttaaa aataagattg gctgatcaat
    42961 ggaaagttct cttagctgac tgactagcgt ttctccgtaa aacactttcg tcaacgcatc
    43021 ttctacttga taatcaagtt ccatacgcat ccctcctctt cttattttta ttttaccatt
    43081 agtaagcaaa ttctagaaaa gataagagca aagctcacct cataacttgc aaataaataa
    43141 aaattaaata aaatacatgt gttttctatg tatgacatac ggattcggaa tctctgtctc
    43201 ttatttattc cttttctgct aggaaataaa aagaaaagca cttgtagccc tagagccaca
    43261 agcgcttttt caactgtctt atttaacagc gtcttttaat gctttacctg gtttgaatgc
    43321 aggtactttg ctagctggaa tttcgatttc ttcaccagtt tgtgggttac gacctttgcg
    43381 agctgcgcgt tcgcgaactt caaagttacc aaaaccgatt aattgaactt tttcgccgtt
    43441 agctaaagca tcttgaatag ttgaaaatac agcatctact gctgcagttg catctttttt
    43501 agttaaatca gtagctgaag caactttttc gattaattct gctttgtttg ccatggatag
    43561 attcacctcc tccacaagag atatgataga aatatcattt agttaaaact ttctgagtgg
    43621 tccagaagtt taaaaagaaa tattgattaa cttcaatatt ctgttatcac gatatcatat
    43681 gaaccgctta atagcaaggt ttttaccaat tttcacatgc tttttttagt catagaaacg
    43741 taacaaacga aactgtcttt ttcttttgaa aaaaaaacgt cgatatggta aaatgcctat
    43801 tttctcctac gagggataat tcggatggac gtcccttcaa aagtaaatgc ttttctgatt
    43861 tgattttcta agaaacgttc ataagaaaaa tgcatcaatt cctcttcatt gacaaaaacg
    43921 acaaatgtag gtggtttgac agcgacttgt gtagcataaa aaatcttcag gcgttttcct
    43981 ttatctgttg gtgttggatt gattgctaca gcatccataa tgatatcatt caacacagcc
    44041 gaagagatac gaagattctg gttcatactt acttgttcga tcatttcagg cagacgttcc
    44101 aaccgttgtt tagtcactgc agaaacaaaa acgattggag cgtaatcaag ataccggaat
    44161 tcatcacgaa tctcttgttc gaaatcacgc attgtattgg tttctttctt tacaagatcc
    44221 catttattca cgacgataat aattccacga ccagcttcat gggcgtaacc cgctactcgc
    44281 ttgtcttgtt cccgaatccc ttcttcagca ttcagtacca tcaaaacgat atcagaacgg
    44341 tcaatggcac gcattgcacg catcacgctg tatttttcag tattttcgta tacttttccg
    44401 cgtttacgca taccagctgt atctatcatt aagaatttct gaccactttc agaaacgaag
    44461 tgggtgtcga ttgcgtctcg ggtcgttcct tcaatatccg aaacaattac acgttcttct
    44521 cctaaaatcg cattgatcaa agaggattta ccaacatttg ggcgaccaat caaactaaac
    44581 ttaatcgtgt cgtcgtcctc ttcttcagtc tcttcagaga aatacttcac tgcttcatct
    44641 aaaatatcac caatccctag tccatggctt cctgaaacag gataaggatc gcctagccct
    44701 aaggaataaa attcatagat atcgtttctc atttctggat tatctacttt attgactgct
    44761 aaaatcactg gtttattact tctgtataaa attttcgcaa ccatctcatc tgcgtctgtc
    44821 acgccttcgc gtccgctgac tacacaaatg attacatctg cttcttcaat cgcgatttct
    44881 gcttgatgct tgatctgatc cataaaaggt tcatcgccaa gatcaattcc gcctgtgtcg
    44941 atcacgctga attctcgacc taaccattca ccttttgcat aaatacgatc acgagttact
    45001 ccaggagtat cttcgacaat cgagatacgc tcaccagcga tgcggttaaa aatcgtagac
    45061 ttaccgacgt tcgggcggcc aacgattgca attgttggat ttgccatatt atttcctcct
    45121 cacaagtttc caatctcact tagtttaacg aatgcattgc caactttcaa gcatagattg
    45181 tcaattaaac gaagtatttt tattccttat tgaaatacta atcgcttttc aaaagaaaaa
    45241 ctgagacaaa agcagctgct ttcatctcag tcacagatac aaaatcaatt atttttcaga
    45301 atcatcggtt gctttttctt ctacttcttc tttcaacgca tcacctaaaa tgtctcccat
    45361 agtaaatcca gtattttctt ctggtaattc ataagactca acattttttg gttcttcttc
    45421 tgaagctggt ttttcttcta aagctttgat actcaatgca atacgatgtt cttctggatg
    45481 gatctctaat actttcactt tcacttcgtc accttcatga agcacttcat gtggtgtcgc
    45541 aatatgttta tgtgaaattt gagagatatg gactagccct tctactccag ggaacacttc
    45601 aacaaaggca ccgaagcttg tcaaacgttt aactgttccg tctaatactg tgccaactgg
    45661 agcttttgta tcgatttctg accaaggtcc aggctgtgtg tctttgattg acaaggaaac
    45721 acgttcttgt tcaggattga tagacaacac tttgacattt acatcatcat tgacagccaa
    45781 tacatcactt ggttttgcta catgactatg tgaaatctct gagacatgga ctagaccgtc
    45841 aattccgcct aggtcgacaa atgcgccaaa atcagtaaga cgtgcaacac gtccactgag
    45901 aacatctccc tcatggatag ttgaaagaat ttcttttttc ttttcttctc tttcgttttc
    45961 cactaccgct ttatgcgata agatcaaacg attttctgat ggttcgattt cgatgatttt
    46021 aaagctcaat gttttgcctt tatagtctga aaagtctgca acaaaatgat cttccaccat
    46081 tgatgcaggg acaaaaccac gtacaccgac gtcaacgact aaaccgcctt tgacaacatt
    46141 tgtaacaggt gcttcgatga ccttgccctc ttggaaatct ctttcgatat cttcccaaac
    46201 ttttttagca tctaaacggc gttttgaaag tagatagctg ccgttttctt tatctttgcc
    46261 gatcgtactg ataacgacta aatctaatac atcaccgact tttactactt cgctgatatc
    46321 ttctaccggc aaagttgata attcttttgc cggaacgact ccttcaactc cagccccttc
    46381 gattccgaca atcacttgtt tgtcttcaat gactaaaact tcgcccttaa caacatcgcc
    46441 aacttttact tcttgtacgc ttttcattgc gtcttccatt gactggttgt tctcttgatt
    46501 ttgatcaaat tctgtcataa cacttgtcct cctaaccaac attctgccgt aagtacggta
    46561 ctgtttttag tttaattgat tattcaaaaa aaataaagcg atttcgttcg ttttccttga
    46621 aaaaacaatt gtttttcatt ttttttctta atttaaaaaa gaagataacc ttttttcaaa
    46681 acaacagctt ttattgctgc aacgacttct ggaatcgatt tgccagtcgt atcgatacga
    46741 acagcatcct ctgcttgctt cagcggagag acgtcccttg ttgaatcata atggtctctt
    46801 tcctgtatct ctttcgtcag tgtttcaaga tcagtcggaa ttcctttttc ttggttctct
    46861 ttgaaacgtc tttctgcacg ctcacttacg cttgctacta aaaagatttt cacttctgca
    46921 ttcggtaata cagctgtccc gatgtctctt ccgtccatga caacgccacc gcgttcccct
    46981 atttttcgtt ggacagcaac taattcttct ctgacttttc catgtgcaga gacttcagaa
    47041 acagcttttg tgacatctgg ttgacggatt tctaaagtca catcttttga tgctatgaat
    47101 acatgctgtc catcttcttg ttgcgaaaaa gagataggat actttttgat cagcgaaact
    47161 agcccttctt catctgaaaa agatacattg ttcgtaatag ctaaataagt tactgcgcga
    47221 tacatggcac cggtatctgt ataaatataa ttcaattctt ttgctaatat cttggcaacg
    47281 gtacttttcc cagatgaagc aggcccgtcg attgcaatac tgatttgtgt catgatataa
    47341 ctcctttttc tcagaaaaaa agccgcaaag cgcggctatt attatttaat tcttaattct
    47401 tgaccagggt aaagcataaa gttgtttgga tctaagccat tcaattcaaa caattgatca
    47461 gtggtgatcc ctgcacgctc agccacttgt tttggacctt cgcctgcttg aacagtcgtt
    47521 gttgaaccgg ctgcagctga tgaagaaggt gttgtttctg ctgcattgct gcttgaatcc
    47581 cctgcttgat aagttgcctc acttgaggaa gtcggtgttg tctctgctgc aatactgctt
    47641 tctgacgtta cacctgtatc ttgagacaca gtagattctt ccgcgattgt actagattct
    47701 actgttgaag tctcagttga ctcctctttt gttgtacttg tagaactttc tactactgat
    47761 gtcgaagttt cagaagaagt tgctgctgtt gcattgttgc ttgatccatt tctgatccag
    47821 aaataagcac ctgctggaat agcgatacat aagaccagta aaatcaaaaa tagcgaaaga
    47881 aataatgtat ttcctttctt ttgttgtctc tgagaacttc ttgatgaaac ttcatcatct
    47941 gtatcgtaga ttggttgttc ccatggttct tgtgtttcgt tattttctgt agattgatgt
    48001 ctatcttttc tgctcactgt tttacctcct aaactctatc gtgtgtatta taccatagga
    48061 aaaagtgtct tgtcctaaaa aatcaatgtt ccatgttttt tttaaataaa tttagtaaaa
    48121 tcgtttccca atgaagttgt tcagtcttag aaaaaagctt cctctttggc agaagttctg
    48181 cttttgctcc atcaatatca caacaattct gcggcttttc ggagagtttt tcgccaaaat
    48241 aagctaagat gaattttctg cggcagtttt cttcattaat atagcgaagc atctgctgca
    48301 ggcggaattc tttttctttt tcctgacgtt tgagccgttc cacccaattt tctggttttt
    48361 cagactgctg gatcagctcc atccattttt tttgcagctc atcaaaggga gcttgctttg
    48421 tggcatattc caaataaagc tcaaaacttt gtcgctgttc tctagaaagt tgattaaaga
    48481 aataatggat acgttcatcc ccactttgat aaaaaagaat tgctgcactt tcttcctgat
    48541 ctctgcctgc tcgaccgatt tcttgtacat agttttctag actgtctggc aaatcataat
    48601 ggaccacata acggatatca gatttatcga tccccatacc aaatgcattc gtagcaatga
    48661 gaaactgcag ctgatttttt acaaactgct gttgaagttg tcttctttga gctgcatcaa
    48721 gaccaccgtg atagtatcca actgtaaaac gttccctgaa taaatgatac aatcgttcga
    48781 cttctttttt tgttgcacaa taaatgattg ccgctccttg tgctctttcc atgaagtgtt
    48841 caagttcttg ttctttttgc tgcgttttcc gaacaaaaag cgagatattt tgccgattga
    48901 ctgattgtct gatctctttt ggtggtcgat caaatagtac atgacgtata tctcttgcta
    48961 ctaaatctgt tgctgtcgcc gttagtgcca gtgtgaccgg gtttcctaaa agctttcgga
    49021 tttttcctaa ctgttgatat tctggacgga aatcaactcc ccattgagac acgcaatgag
    49081 cctcatctac tacatataac gcaatatttt gttttttcag atgctctaaa agagaaggat
    49141 tagtcaacat ttcgggactc aaaaacaaaa atttatattg cgatagatga cggaggacgt
    49201 atcttctttc agattgcgaa agtaaactat tgaaagcagc tactcgtttc tcccctcgtt
    49261 tttgtaattg cgtcacttga tcttccatta gagaaagcag cggtgacacg atgatgacca
    49321 gaccttccat taaatacccc gtcaattgat agcaaaggct ttttcccgtt cctgtaggca
    49381 aaatagcgag agtatcttct ccatcaagca acgcctgaat aatctcttct tggccgggac
    49441 gaaatgaatc aaatccaaaa tattttttta attcatttat taacattctg tatcgcttcc
    49501 tttctcaata gatagatttg atacaaacga aattctccat aatctaattg tccatctaca
    49561 ttccattcgc taaagcgcca ctctcgcacg gaatccttat ttggttccaa acgttcgatt
    49621 gtttctgcag agagaatcca ctcgtatgga aaatcatcaa aaaacaaggc ccactcaata
    49681 agatgatctg ttactgttcc tctttttaaa tgacggattg ccatgatctg gtcaattgtc
    49741 tgaccattca taaacatctg cttggtgatc atcatgcttt gattgaaatt ttgctgtaat
    49801 aatgaatcga tcaaagcgtg ccaaagcgaa tctggccgtt tttcgatttg tgctaacaaa
    49861 aggtggatac atctgctttg ttgcagataa acctctgact catcattgtt ttttgccagc
    49921 tgataaggaa gcagccctgt tcgctcattt ccagataatt ggttagctaa aaaatctgct
    49981 gcttcttctg gtatctccga aaacagctgc accaaactct catacgcagt atcaattaaa
    50041 atttcacgtg gcaattggct ttcactaagc cattttttta gttggaaagt ataaaaagga
    50101 cttgtctctg ctggaagata gtcttgaata cccgttgcca gattagaaat tacttgaaca
    50161 gcaaatttaa tgagccgcca actagtttcc cctgttctgc catagcggtc aaaacgcaaa
    50221 ccagtatgtt ctatttgatg ttcggacaac atatcagccc ctgcaggcgt tagctttgct
    50281 tcattttcat ttatttcgat ccaaccttgc tgcgcaattt tttgcaaaat ttgataaaac
    50341 ttatcctgct tcaattctgg aaaactgtta tggataaaca aaagttcgtg ggtaaatcca
    50401 taaataagta ctgaagtcgt tcgttttccc acaaggagtt ggtaaagaga actaatccgc
    50461 agcttgtgtc ctgatgaaaa tagcgataaa ataaaaacaa tcatattatt ctccttaagt
    50521 taggatggtt agaaatgtca ctactatgta aacttgtacc tgaacgctgt attgcatgcg
    50581 gtctttgtca aatcgaagcg ccagatattt tcgattatga tgaagaagga atcgttttat
    50641 ttgcccaaga accagaggct catcaacagt tcgtgatgcc ggaagaagaa acatatgtaa
    50701 aaaaagcgta tcaaaaatgt ccagttcgag cgattttatt agaaaataaa atataaatat
    50761 aaacgaaact ttaaaaacgt acactaagtt ctctaaactt gaaaataagc cgggatctgt
    50821 ttctcttgtt ccgtgaaatc ccgacttatt ttgaaagatt catttgctat ctatagttaa
    50881 ttgactagtt ttttcacgga ccctatagga cccatttata ttatttcaac tttttcagcc
    50941 agttttccaa tgtattgacg atcacagttt gctggtctgc gttagaaatt tctgcctctc
    51001 catctccttt ttgctcacca tagctgccaa aacctccatg atttccgcca ttgattgata
    51061 catactctgt tctttccggt aaatactgct tagcttcttg ataagcttcc tgattcaata
    51121 ctttatcttt tgtcgccgtg atcgataaaa caggaacagc tgattctgtc aatgttcctt
    51181 ttttgtcggg ataacttgcc atgaagaata ccccttttaa atgtttgtct gaatgattct
    51241 tattgacata acgacttgcc attacgccac ctaatgaatg gccaccgatc acataatcgg
    51301 aatttggaaa atcttctttg accttatccg ctttgtttcc gcccatcact gctagatcaa
    51361 gtggcatttt gacaatagcg actgaaaagc cgttttttgc taaatcttgc gcccaaatac
    51421 tataactttc tggctctacg agagcaccag gataaaaaat aagtaatgga gactttccat
    51481 gattcttttt ctctccttca aaaaataagt aatcttcttt gttttttcct tcttttacca
    51541 acacttgcgc ttctgacgat ggttcgtacg tattttgctg tatatagtaa taaccggctc
    51601 caccgagtaa tcctaaaatg atgactaagc caattagtat tcgtctaaat attttcactt
    51661 tctcccacct tttctatctg agtgacccct ttttcttaat caagtatgat tataccttaa
    51721 aaaaataaga gagaaatgca aactttccag catcaaataa aaaaagacgg aatatccatt
    51781 tgaatatccg ccctttttgt atgtttattt ttatttagca cataaacgat acacagcttc
    51841 tgcataaatt tccattgctt tatacatact acttaattcc catcgttcat tcgcctggtg
    51901 cataaagtca ggagtatcag ggaacatcgc accgaatgcc acacactggt tcatcgtacg
    51961 agcaaaagta gcgccgcctg atacaaacgg ttcagtcatg tctccagtaa tatcgcgata
    52021 tgtccccaat agatttttca ctaactcact gtctagtggc acgtataatg aatcaaggaa
    52081 gtcaaattct tcataagtca acccatattt ttctgctgtt ttagttaatt tagctactaa
    52141 atcatctttc ttgaatgtaa cagggattct catatctaca ccgatttttg tttgttctgg
    52201 tgtgatttcc aaacttgcaa agttcatcgt tagctcgccg gattgttcat cttctgtttt
    52261 gcccacgaca gcttcaccag ttgcattttc ttgaactaat tttcctaaga aattgattgg
    52321 gccaaaatca aatacttctg aaagagcaat tgccagacga gaaatagcat tcactccttg
    52381 tgctgcatct ttcgcgtgga tacttttacc aagaacgacg atgccttcac cttgttcttc
    52441 gaaatcgaat tcgtgttttt tcaatgcttc ttttacttca gaaagctttt ctccagagta
    52501 aggagctgca tcaggaacaa cattcaacgc tcctccagct tttacagaaa actcgttcgt
    52561 tcctggtcct gtcaagtaag cttgcaataa gcctttttct gcataaatta aaggaaattc
    52621 agcatctggc gcaaatcctt gcgtaattcc ttcttctttt tcgttatatt tttctaaaca
    52681 acgccataaa ttttcttcat ctgtaccaaa gataaaacga atacgtgtct tgaattccac
    52741 gccagcatca atcaaagctt tgacggcata cattgccgca atagaaggac ctttgtcatc
    52801 ttgggatccg cgaccaacta accagccgtc ttttatagtt ggatcgaatg gttttgtttc
    52861 ccaattattt tcgtcccctg ctggaacaac gtccatatga cacaagatac cgaataattc
    52921 atctccagag ccaatctctg aataaccgta atagccttct ggatctttaa atgttctaaa
    52981 tcctagcttt tcactgattt ccaatacttt atccaaagct tcaatcactt ttttaccgaa
    53041 gggatgtcct tgtcctgaat ctgcttcatc tagtacggaa ggaattcgga tcaattcgct
    53101 caatgattct aatgcttgtt catgatgttg ttctgtcaca aattttttca tgatattatc
    53161 ctcctaatat gttaaaaagg gtcatgtcaa attcctccga cacaacctct tcttctcaaa
    53221 taatgacgtt ttaagcctgc tccatcagca agcagaatgt tcttaacaaa tgatgaaaga
    53281 aaaaacactc actgaatgga gctattgact tatccacgtg cttatcgata gccgtttatc
    53341 ggtttcttca ttcttatgat agaccttgta cctgtatttg tctaggttta gaacattgct
    53401 gctacaccta ggatcacaca gatggctaca aataatatcg caattaattt accggtaaat
    53461 ttccaccaca ctgaaacatc gaaacgagca attgctacag cacccattac gatagcagat
    53521 gttggtgtaa ttaagtttac taaaccagat gcagattgat aagcagtgat tactaaatcc
    53581 ttaccgacgc cggcaaattc acccataggt cccatgattc ccattgttgc agcagctaag
    53641 ccggaagttg aaggaatcaa gaatgacata gggatataga aaataaatgt aataatgatg
    53701 aatacacttg aagataatga acttaatcct tgttcgcccc aatgtaagat ggtgtctgtg
    53761 attaatccat tgttcataac cacttggata ccacgagcaa cagctactac gattgctaca
    53821 ccgatcaaat cagaagcacc agctaaaaat tcagagacaa attcagactc tttcatgcca
    53881 taagtgattg ctactacgat ggacattact aagaataaca tagtaatttc tgggaagtac
    53941 cagtcaccta atggaagcat gcttttacct agaaccgtac ctagtaccgg aaggtttgtt
    54001 aaccagtttg tcaatgattc aaaaatcgtg aaattcgcat tcaaggttgt ccaaggaatc
    54061 aaactgatga tcatgatacc aaaagtaata aagaacaata cattaacatg tttttgtttt
    54121 ttcgtgatta cttcttgacg accgattgct tcaatatcga aatgcttcat atcttcttta
    54181 cgttggttgt atactaatga ttttgttgga tctttttcga tctttgatgc ataacgatac
    54241 acatatacaa tagaaatagc taacaaaata acgaacatca agaatcgaag accaatacct
    54301 tcacccatcg aaatcccaac agcttgtgaa gctacgcctg ttgcaaaagg atttaccgtt
    54361 gaagctagac agcctacttg agaccctact aatacgattg ctacagctac tactgtatca
    54421 aagcctacag ccatcatgac tgggatcagt aaagcataga atggaatcgt ttcttctgcc
    54481 attccgtaag tagagccgcc taatgcaaat aacagcatca atactggaat aagcattttt
    54541 tcttttcctt tgaatttctt cacaactgaa gcaatcccgg catctagtgc ccctgttttg
    54601 ttgataatac ctaaaaatcc accaacaacc aaaatgaaga aagagattgg gattgcagca
    54661 ggtgtttctt tagttagctc ccccgctggt acacctagca tcccattgat tggcgccatg
    54721 aaaatatccc acagcccttg aggattttgt tgtactcgtt catatgatcc agcgacgatg
    54781 ttgcctgcat cgtctacact atagtgccca gctggtataa accaagtaag tacagcgatt
    54841 actgcaataa taataaataa gaccgtatac gctgaaggca tttgaaattt tttctttttt
    54901 gtttgttcca tcttcttctt cctttctttt ccgttagaga caacaatttt ggctctaatg
    54961 ttattttatc aaaaagagta tcagaacaaa aataataaca cgcattttgt aaaacttttg
    55021 ttcaaaaagt tcgtttttcc ctattccctc ctcttttttc aggtttttaa agctttcttc
    55081 tttttcattg tagcgtttcc ttttttttat aaacaaacat tttcgtcttt taaaaggaga
    55141 agaatttcac atttgcaaag aattgattga tttttatgca taaatcaaaa aaatactcaa
    55201 aacaaacaaa taaaacgttt acattattgc atgtcttgta tttttttcca aaaaaaaaag
    55261 accaagaaat ttcttgatct ttttgatatt tatttgactg ctgtatgacg ttgttcgaac
    55321 tgatgttgtt ttcgacttaa ccatggaaga agttgcgcat gcagcactaa aaagacagca
    55381 ctcacgatga atcctttgat caagttgaaa ggaacgatcc caatcagtac atagtttgct
    55441 aaagacatgc ccagcatctg tgttgcgttc agccctaaaa acattaagta aagaggcgta
    55501 ataacgaaat aatttgcgat actcataaaa atagttagag cgatggttcc tgtaatgaca
    55561 cctaaaaatt tgtttcttcc tttatgctgt ttctttacac taaagaaata ataaatcggg
    55621 aatgtaaaga tcgttgttga taagaaacta gcagtgtctc ctaccaaatt atccggagaa
    55681 aaacctgtag tcagcagatg taatactgaa cgcaagaacg ctgttgcaac tccggccgct
    55741 ggaccgaata agaacatgct gatcaatacc gagatatcac taaaatcgat cttcaaaaaa
    55801 ctaaaagccg gcatgatcgg aaaagcaaaa tactgtaaaa ctaatgcgat cgcagcaaac
    55861 atcgctactg caaccatttt ctgtacacgg gtgttcttca tttgaaatcc tcctgttagg
    55921 actcctcttc agcgaacttt ttgacgtttc tctccaaatg aaaaaactct attttccagg
    55981 gaaaatagag ttagagttat ttgatcaagc gtcgtcaaat aagctctatc ttctttatcc
    56041 agactatact gtcggtatcg gaatttcacc gattcagcta tttttttgca aaataggtcg
    56101 tggactataa ccaccggtcg ggaatttcac cctgcccctg aagacgaacc ttatataatt
    56161 tttgtttaca tattcattat acatatctat tcaaaaaacg caacatctaa cacttataaa
    56221 aagtaagtgt tcattttgag tggttcagca aactgctgac ttcttttttg ttcagttcac
    56281 ggtaatcccc aggacgtagg ccttgtaaag tcagatctcc gtatttttca cgttttagtt
    56341 tttgcacagg aagaccaact gcttgaagca tatttttcac ttgatgatta cgtccttcgt
    56401 ggatcgtcaa ttccacgata ctgtggtttg tcttaggatc cactgataaa atttggaatt
    56461 tagctggaga tgtttttcgt ccttcgatct ttattccttt tgtcaaaggt gcaagcatcg
    56521 attttgtagc gatccctttt acctttgcaa cgtaaacttt atccacttca tgttttggat
    56581 gtgtcaggcg ctgagcaaaa tctccatcat ttgtcagtag caagatcccc gaagtatcgt
    56641 aatccagtcg acctacagga tagatacgtt cttttaccat cggcaaaaga tccgtaacaa
    56701 cttttcttcc tttgtcatct gcaacagcag aaataactcc tttaggtttg tacaataaat
    56761 agtaaccgta ttcttcttga taaattggga cttcatccac ttccacagtg tcatgtttcc
    56821 caacttttat ccctaattcc cttacaactt gtccgtttac ttttacacgt cctgcaagga
    56881 tgaattcttc tgcttttcga cgagaagtga tgccagcgtg ggcaattact ttctgcaatc
    56941 tctccattac aattattctc ctttattcat tccatcaaag aatagatctg gtgacacgtc
    57001 ttcttcaagt gaaatttcca tttcttgtgt atcaggcagt tcttctaatg atttcaaacc
    57061 aaaataatct aagaagtagc cagttgttcc atataatatc ggccgacctg gtccttctac
    57121 tctacctttt tcttcaatca gtttatgggc agctagacgc tgtaccgctc ctgaaacctg
    57181 aactcctcga atctgctcga tttcagctct tgtgattggc tgtttataag cgatgattgc
    57241 taaggtttcg acggcggctt gagataatgt gtttgatgtc ccttgcgcat atcgcttaag
    57301 taagggagcc agctcttttt tagtcgttaa tacataatgg ctttccgttt caaaaatatg
    57361 caaagctgag tgcgagtttt gagtgtaaga ttcttttaat tctttcacta aacttgtgac
    57421 ttctgcttcg ctgagattta acagtccgct taattcttca ttactgatcc cttcctcgcc
    57481 aacaataaaa agaagggctt caagttcact taatttcgtc atgttcggta tctcctactg
    57541 ctggataaag cataattgat tcatagtttt ctttttgttg cgcaatgatc tgcccttttt
    57601 tcatcaattc tagcaaagcc ataaaagtag tgacaacttc acttttagaa ggtgactcaa
    57661 aaaaagaatc gaaagtacag ccatgcgcat ttctttttat acgctcttcg ataaatacca
    57721 ttcgttcttc gatcgttgtg tcatcgggcg tgatcgtttt ttccactttt tgagaaaatt
    57781 tcttacgttc taagattttc tgcatggcac ggatcaaatc gatttttttg acttgtcctc
    57841 gcttcaacgg cttttcagca tccgctaacc catcgatgtt cataggttct tttgtgtaat
    57901 aaagacttcg ttcctctgct ttttctgtca gtctttcagc tgcatattta tatttacggt
    57961 attctaaaag ctgagtgacc aattcttctc gaggatcttc ttcccataat tcttcatcgt
    58021 ctgtgacgaa ttcttggaca ggaagcaatg tcttgctttt gattgccatc aatgtagcag
    58081 ccatcactaa gtattctcct gcaacagcta gctcgagtgt tttcattgta tggatataat
    58141 tcatatattg ctccgtgatc gtagcgatcg gtatatcata tatatcgatt tccatttgct
    58201 gaatcagatg aagcagcaga tcgagaggac cctcgaatac atctaattta atattgatct
    58261 ccgtcaactc attcactctt tcttcttttt ctttgctagc cattttccaa tgtaaggctc
    58321 tgtgatttca gttgcacgga tggagacatc cgggtacttt tcctgtaatt catctaacat
    58381 ttgaaagccc atattctcac cgcgataaga cggattcaaa gaaatgtcat ggatgatcag
    58441 ctgatcgttc gttgcccagt aaataccaat aatcccttga atgttggttg aaccttctgg
    58501 cgtaaagaaa aaaagttcat aatcgtcttc agattcgtac gtatcaatct ccttcaacaa
    58561 agaagtttta cctgtcagtt tcttatggaa actcaatagt cccatagcaa ttttacggtt
    58621 ttctttccgg taatgtgtta acatcttctc accttcctat gactaagccc ttggaaaatg
    58681 ctgcttataa acatccgtca ttcttttctt cgtgatatgt gtataaatct gagtcgtaga
    58741 gatatccgcg tgacctaaca attcctgtac tgtccgcaaa tcagctccat tttctagcag
    58801 atgtgtggca aagctatgcc gcagcgtatg tggtgttact tctttgtaaa tcccagcctc
    58861 tcgtactaac tgcttcagat ttttccagat tccttgccga gaaagacctt tcccatgatt
    58921 attgacaaat acatgcattt cagatgcgtc ctttacaagt aatggacgtg cttcgtctaa
    58981 gtagcgttcc agccattgga tcgcataatc acctaaagga atgatccgct ctttatctcc
    59041 ttttccaact gtctgtacca gtccaagaga aagatgaaga tctcccaatt tcaatccaat
    59101 caattcactg acgcgcatcc cagtagcata catgacttcc aagattgcac gatctcttat
    59161 ccctaacgtt tttgtcgtat caggtgcttc aatcagcttt tctacttctg tcagagtcaa
    59221 tgtacttggt aatttctgtg ctttcttcgg cgtatcgata tgttgcatcg gatcatgatc
    59281 agtgatacgc tcttgccgta aaaactgatg gaatcttctg agacttgaga tcatccgagt
    59341 aacagttgct gtcgcttttt tttcttcatg caacttctcc agaaaacgga tgactaaaaa
    59401 gcgatcgaca tcctgccatg aagcaatttt ctgctcctgt agaaaatgca agtactgttc
    59461 caaatcacgt tcatagcttt gtcgtgtatt ggcggacaat ccccgttcaa tattcaagta
    59521 gtggagataa tcgttgattt gctctttcat aataatcccc ctcatgcctc tctatcatat
    59581 cagataccgc ttcattctga tagtcttttt ccataatctg agcaaagaaa aagccgtcta
    59641 gacactcaga cggactggtt tcttttttct ttttcatagc attcctgaca gattccatgg
    59701 aacgttagcc gatgatcttt tactaaaaaa tgataacgtt cttctactac ttgctccact
    59761 tcaagtaaaa gatcctcttc tacttcctcg atcgtgccgc agttcaagca tagtaaatga
    59821 tgatggaaat gtttggcgcc ttcttttctc aaatcataac gggctaatcc atcattaaaa
    59881 cttactttat cgacaatttt caattctgtc aagatttcaa gggttcgata aacagtagca
    59941 agtccaattt ccggactctt ttttttcact aaaaagaaga tttcttctgc agataaatgc
    60001 tctttctcat tttccaaaag cacaagcaga gtagcttctc tttgcggtgt cagcttaaac
    60061 cccgcttcat gtagctgctg ttttgttttt ttcatcgccg aaatagcatt catgaccatt
    60121 tactcaaccc caacaattta taataattac aaataaaaaa agatataaca ctatgttaat
    60181 taaaattatt ataagctagt taagaaaaac atgcaaggga ttctcaatta gattttttga
    60241 ctagttttgt cacaccgttt tcttgtgtaa tcaatccttg tttcaaaaga ttacctaatg
    60301 cgcgcttaaa tgctcctttg ctgataccaa aagctttcat gatttcttct ggatccgatt
    60361 tatctgtaaa gttgatttgc tgatctgcag aacgttctaa aatggttaaa atcatttgtg
    60421 catcatctga tatagcttca tatgctcttg gcttcaatga aagattcagt acaccgtctg
    60481 gtcggacacc aatcactcga ccttttatct gctcgcctag acgaggttca ttatatcgtt
    60541 cagaaggatg gataaaccca agatagaaat cttccgttaa aacgtacgta cctgttaatt
    60601 tcaagcggta tgctgttcct atcacatctt tgtttttcat ttcttctgtt ccatatttgc
    60661 ttaaagattt gaatattttt tcatctgcta aactgcccca aatacggtct tttgcatcaa
    60721 ctctaaggga aatcatcaag cgatcccctt ttttaggcca tagctctgtc attgtcggca
    60781 attcatcaag agatacgaca aagtctttat ctggaagacc gatatcgaca aacgcaccta
    60841 aatcttttcg tgtagcagta acgattccaa aagcgtaatg accgatacgg cttttaggaa
    60901 tttgtgtagt gatccgattt tcatgttttt gattttggta accgaatcct tcaactgctt
    60961 caccgatttt gtgttcacct tctgatttgc ttaagccaaa ggtttgtccg tttttttgga
    61021 caaagtagtt tttttcattt tcatcaataa taatacctgt aaatatagtt gctaataaat
    61081 cgttcatttt tttctccctc tatagtgaaa ggttttctta atacatttct ttgctatcat
    61141 aacataatgt tatctacttg aatagctgag ccttggtttg gaaaggtgaa aaaaggagta
    61201 tgacaacagt tgtgtcatac tccccttttt cgaataaacg gtgttaaacg gcaggctcac
    61261 agcctctttc atttgcctaa aattaattgc tcccatttcc tccgaaccat ccagttttac
    61321 agttgatggt tacgatgtaa aatggcaaag cactttctcc aatgcctttc atcaatgcag
    61381 attttgttga agtggcatat agattataat agccttcccc attttcgatt ctggcttttt
    61441 ctaatctgta acctccttca acgatatatc cacgttggat acatgtagca atcactttgc
    61501 tttggacacc tggtgcccac gtccatgctg gattagatgc atcggcaata tcacttgctc
    61561 tggcagattt gattggctga ttcgctgagt ttgaagagga aggggtcgag gatgccgctt
    61621 cttgctgtgc tgcttgtgcg accgcagctt gttgagcggc ttgagctgca gctgctgctt
    61681 gagcggcttg ttttgcttgt tcttcagctg cttttttcgc ttcttctgct tttttctttt
    61741 cctcttcttc ttttttctct ttatcagtga gcatcttatc tacttgtttc aattgttcat
    61801 tcaactgagc agatagatct gtatttttca ctttttctac tgcttctttt gccgtcttgt
    61861 attggtcgcg tgttgctgaa tccactactt ttccgtcttt aaagactata gctgtttttt
    61921 ctttagctgt ttgcaattca gcatattgat ttttagcttc tgtttgtgct tgttgaatca
    61981 attttccaaa atctgtgtta tccgtttcga ttgcttggat ctctttatct gctttcaact
    62041 tgatgtcatc tgctagatga tcatcgacga tggcaggtgc tatgaaccac tcattcactt
    62101 tttggatatc tcggatctta gattggatat cttggtaagt tgtttctaac tctgaatatc
    62161 ctttttcatt cttaagactg gataaatcat tttttagttt tgataaatct tgatgaatca
    62221 tatctgcacg aataaattga tggtgatcat ctgtataaaa ggcagcaagt ttctcatgaa
    62281 gttcttccat ttgttgctgt ctttttgctt ctgctgctac ttcggcttct actttttgat
    62341 gatggtcata ataagcccag cttcctccac cgagtagaag tactgctgct aaaacgagat
    62401 aaggtacttt ttttgatttt ttcttttgcg ctttatctgg atctgttttt tctaagtttg
    62461 attcttgatg tgttttttca gtatctggca cgattgttat tgatttcgct tctgcttcaa
    62521 acagcttagg ctggttctct tctttttcta tttttgcttc aagatcagta ccctctttgc
    62581 ttacagattg attttcagca tcggattcac tatttatttc atcgggctct gttgactttt
    62641 tgtctgtgtt ttcgagtatt tcttttttct ctgcttccgg cagtttattc gttttttcct
    62701 tttctaattg tttttcagta aatacttcag ttttttctgt gatatccgtt tttacgtctt
    62761 ttatttttac tgtttcttta cctgtggcgt tttctctatc agagtctttt tcagtttctt
    62821 gttccttttc tggctctact ttgttttcct gtgcaatttt ttcactgatc attttgagca
    62881 gctctttcgc gtgctcttct tttgtatctt cacgatgtgc tttgatataa gcggatagta
    62941 tcgaattttc ttcctcatta tcgacgattt ctttcagttc agctactctt cttttttgtt
    63001 ttgattcaag cgtttcttct tgattctttc ctgattcttc cgaagtctca tgaacagttg
    63061 ctttcttctg ttcatttttc tctatattag ttacttgatc gtgagcaggt ggttcttcgt
    63121 cttctggttc tgctttttcg aataattcca ttacagattc tagaggtaaa tctttcaatt
    63181 ccgaccattc gattggatcg tttaattctg tatcaggaaa gactgcatct tcagttgatt
    63241 tatcctgcat agctgcatct gtatttgttt cttcaattga ttcttttatt tgctgatctt
    63301 ctgcagttat ttgatgaccg cagtctggac agatagtatt ctgctccatt tttttcgatc
    63361 cgcaatttgg acattttttc atcacttagc gatcggctcc tttactaggt ttacgctacc
    63421 atttaatcta tcatattcta tacgtcacgc caatagctta tttttaggat ttacttaaaa
    63481 ataatgaatg aatttccttc ctatagaaaa aaaagcttga gactgcgtag tctcaag
//
LOCUS       DAPBBR010000010        63130 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPBBR010000010 DAPBBR010000000
VERSION     DAPBBR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 63130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.010"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..2267)
                     /gene="esp"
                     /locus_tag="RD488_000642"
     CDS             complement(<1..2267)
                     /gene="esp"
                     /locus_tag="RD488_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HDT7656741.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGAGLVLGTT
                     ELVKAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVVRYVLQLTKPLDEILKEMKTAAQVEGNEPFGEDFIFDCWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGNVLAEKDIAPNEKDGAPVSGTVDFEFTGVDSSKLIAKDELKVQIVST
                     GFDKAEEGSTIIKESPKAIDKQTVVVGFKPDAKESIRNNQSLPDNATYSWKTEPDTSK
                     ATDNTKGVVTVTIGNRTFDVAVEFAVEASQAMENNATYDAIETQPETTVQSGKPKFDK
                     DDVRLSNNPFAIDDTFDETQGKVTIDSATGEVTFTPEKGIGEDKPTKVTIPVSVTYED
                     GSVGKTELIVTVGKG"
     gene            complement(2882..3316)
                     /locus_tag="RD488_000643"
     CDS             complement(2882..3316)
                     /locus_tag="RD488_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656742.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3333..4537)
                     /locus_tag="RD488_000644"
                     /pseudo
     CDS             complement(3333..4537)
                     /locus_tag="RD488_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
     gene            5231..5617
                     /locus_tag="RD488_000645"
     CDS             5231..5617
                     /locus_tag="RD488_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7656743.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5711..5902
                     /locus_tag="RD488_000646"
     CDS             5711..5902
                     /locus_tag="RD488_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656744.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6416..6748
                     /locus_tag="RD488_000647"
     CDS             6416..6748
                     /locus_tag="RD488_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7656745.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7044..7199
                     /locus_tag="RD488_000648"
     CDS             7044..7199
                     /locus_tag="RD488_000648"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HDT7656746.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7475..8815
                     /locus_tag="RD488_000649"
                     /pseudo
     CDS             7475..8815
                     /locus_tag="RD488_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9056..10672)
                     /locus_tag="RD488_000650"
     CDS             complement(9056..10672)
                     /locus_tag="RD488_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7656747.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10790..11008
                     /locus_tag="RD488_000651"
     CDS             10790..11008
                     /locus_tag="RD488_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656748.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11029..11664
                     /locus_tag="RD488_000652"
     CDS             11029..11664
                     /locus_tag="RD488_000652"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7656749.1"
                     /translation="MVRHLFVDFQWSPEEISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11857..12096)
                     /locus_tag="RD488_000653"
     CDS             complement(11857..12096)
                     /locus_tag="RD488_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656750.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12120..13643)
                     /locus_tag="RD488_000654"
     CDS             complement(12120..13643)
                     /locus_tag="RD488_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7656751.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMAAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFLGGESQEKLYNEMHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13661..13783)
                     /locus_tag="RD488_000655"
     CDS             complement(13661..13783)
                     /locus_tag="RD488_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7656752.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13813..14796)
                     /locus_tag="RD488_000656"
     CDS             complement(13813..14796)
                     /locus_tag="RD488_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7656753.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFKSDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14820..14969)
                     /gene="rpmG"
                     /locus_tag="RD488_000657"
     CDS             complement(14820..14969)
                     /gene="rpmG"
                     /locus_tag="RD488_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7656754.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(14990..15367)
                     /locus_tag="RD488_000658"
     CDS             complement(14990..15367)
                     /locus_tag="RD488_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656755.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15399..15578)
                     /gene="rpmF"
                     /locus_tag="RD488_000659"
     CDS             complement(15399..15578)
                     /gene="rpmF"
                     /locus_tag="RD488_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7656756.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15593..15862)
                     /gene="rpsN"
                     /locus_tag="RD488_000660"
     CDS             complement(15593..15862)
                     /gene="rpsN"
                     /locus_tag="RD488_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7656757.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16385..18151)
                     /locus_tag="RD488_000661"
     CDS             complement(16385..18151)
                     /locus_tag="RD488_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656758.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKVVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18111..19865)
                     /locus_tag="RD488_000662"
     CDS             complement(18111..19865)
                     /locus_tag="RD488_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656759.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(19975..20544)
                     /locus_tag="RD488_000663"
     CDS             complement(19975..20544)
                     /locus_tag="RD488_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HDT7656760.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20562..21974)
                     /locus_tag="RD488_000664"
     CDS             complement(20562..21974)
                     /locus_tag="RD488_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7656761.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKISSPFLVMQEMDYQFFTES
                     VRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNLF
                     LFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKKD
                     IKLRVEDSTLIEQIFNDITK"
     gene            complement(21985..22653)
                     /locus_tag="RD488_000665"
     CDS             complement(21985..22653)
                     /locus_tag="RD488_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7656762.1"
                     /translation="MLKINPLTLITLNIFFPVIIFLGKGNTFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22783..23367)
                     /locus_tag="RD488_000666"
     CDS             complement(22783..23367)
                     /locus_tag="RD488_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7656763.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23698..23931)
                     /locus_tag="RD488_000667"
     CDS             complement(23698..23931)
                     /locus_tag="RD488_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HDT7656764.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKVFK"
     gene            complement(23946..24893)
                     /locus_tag="RD488_000668"
     CDS             complement(23946..24893)
                     /locus_tag="RD488_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7656765.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24893..25735)
                     /locus_tag="RD488_000669"
     CDS             complement(24893..25735)
                     /locus_tag="RD488_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7656766.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            26057..27244
                     /locus_tag="RD488_000670"
     CDS             26057..27244
                     /locus_tag="RD488_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7656767.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(27336..28076)
                     /locus_tag="RD488_000671"
     CDS             complement(27336..28076)
                     /locus_tag="RD488_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7656768.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            28764..28922
                     /locus_tag="RD488_000672"
     CDS             28764..28922
                     /locus_tag="RD488_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656769.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            28994..30214
                     /locus_tag="RD488_000673"
     CDS             28994..30214
                     /locus_tag="RD488_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7656770.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQTLSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKTVFEAFQKGLKN"
     gene            complement(30307..30699)
                     /gene="rpsI"
                     /locus_tag="RD488_000674"
     CDS             complement(30307..30699)
                     /gene="rpsI"
                     /locus_tag="RD488_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7656771.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(30715..31158)
                     /gene="rplM"
                     /locus_tag="RD488_000675"
     CDS             complement(30715..31158)
                     /gene="rplM"
                     /locus_tag="RD488_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDT7656772.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(31677..32144)
                     /locus_tag="RD488_000676"
     CDS             complement(31677..32144)
                     /locus_tag="RD488_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDT7656773.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(32264..33802)
                     /locus_tag="RD488_000677"
     CDS             complement(32264..33802)
                     /locus_tag="RD488_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDT7656774.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            33882..34568
                     /locus_tag="RD488_000678"
     CDS             33882..34568
                     /locus_tag="RD488_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDT7656775.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(34769..35296)
                     /gene="msrA"
                     /locus_tag="RD488_000679"
     CDS             complement(34769..35296)
                     /gene="msrA"
                     /locus_tag="RD488_000679"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7656776.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(35380..36057)
                     /gene="pgmB"
                     /locus_tag="RD488_000680"
     CDS             complement(35380..36057)
                     /gene="pgmB"
                     /locus_tag="RD488_000680"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7656777.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(36054..37184)
                     /locus_tag="RD488_000681"
     CDS             complement(36054..37184)
                     /locus_tag="RD488_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7656778.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(37184..39367)
                     /locus_tag="RD488_000682"
     CDS             complement(37184..39367)
                     /locus_tag="RD488_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7656779.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAVLKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(39364..40389)
                     /locus_tag="RD488_000683"
     CDS             complement(39364..40389)
                     /locus_tag="RD488_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7656780.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(40434..41261)
                     /locus_tag="RD488_000684"
     CDS             complement(40434..41261)
                     /locus_tag="RD488_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7656781.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(41258..42325)
                     /locus_tag="RD488_000685"
     CDS             complement(41258..42325)
                     /locus_tag="RD488_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDT7656782.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(42351..43187)
                     /locus_tag="RD488_000686"
     CDS             complement(42351..43187)
                     /locus_tag="RD488_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7656783.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(43184..44053)
                     /locus_tag="RD488_000687"
     CDS             complement(43184..44053)
                     /locus_tag="RD488_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7656784.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(44123..45406)
                     /locus_tag="RD488_000688"
     CDS             complement(44123..45406)
                     /locus_tag="RD488_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDT7656785.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(45420..47105)
                     /locus_tag="RD488_000689"
     CDS             complement(45420..47105)
                     /locus_tag="RD488_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HDT7656786.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            47380..48405
                     /locus_tag="RD488_000690"
     CDS             47380..48405
                     /locus_tag="RD488_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7656787.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(49000..52674)
                     /gene="rpoC"
                     /locus_tag="RD488_000691"
     CDS             complement(49000..52674)
                     /gene="rpoC"
                     /locus_tag="RD488_000691"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDT7656788.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(52732..56349)
                     /gene="rpoB"
                     /locus_tag="RD488_000692"
     CDS             complement(52732..56349)
                     /gene="rpoB"
                     /locus_tag="RD488_000692"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7656789.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            57077..58045
                     /locus_tag="RD488_000693"
     CDS             57077..58045
                     /locus_tag="RD488_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7656790.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            58063..58968
                     /locus_tag="RD488_000694"
     CDS             58063..58968
                     /locus_tag="RD488_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656791.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            58965..59771
                     /locus_tag="RD488_000695"
     CDS             58965..59771
                     /locus_tag="RD488_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656792.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            59907..60896
                     /locus_tag="RD488_000696"
     CDS             59907..60896
                     /locus_tag="RD488_000696"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDT7656793.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(61213..61737)
                     /locus_tag="RD488_000697"
     CDS             complement(61213..61737)
                     /locus_tag="RD488_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HDT7656794.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            62024..>63130
                     /gene="scm"
                     /locus_tag="RD488_000698"
     CDS             62024..>63130
                     /gene="scm"
                     /locus_tag="RD488_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDT7656795.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSD"
BASE COUNT        19145 a        12693 c        10603 g        20689 t
ORIGIN      
        1 ataccttttc caactgttac gattaattct gttttcccta ctgatccatc ttcataagtt
       61 acagaaacag gaatcgttac tttagtaggc ttatcttctc caataccctt ttcaggcgta
      121 aaggttactt ctccggtcgc tgaatcaata gttactttcc cttgtgtctc atcaaaagtg
      181 tcatcaattg caaaaggatt atttgataaa cgaacatcat ctttatcaaa tttaggtttt
      241 ccactttgaa cagttgtttc tggttgagtt tcaattgcat catatgttgc attattttcc
      301 atagcttgag aagcttctac ggcaaactct acagccacat caaaagttcg atttccaatc
      361 gtaaccgtta caacaccttt agtattatcc gtagctttag aagtatcagg ctctgttttc
      421 catgaataag ttgcattgtc aggtaaactt tgattatttc taattgattc tttagcatct
      481 ggtttaaacc cgactactac agtttgctta tcaatagcct ttggtgattc tttaataatt
      541 gttgaacctt cttctgcttt atcaaaacct gtagaaacga tttggacttt taattcgtcc
      601 ttcgcaatta atttacttga atccacacct gtaaattcaa aatctacagt acccgaaact
      661 ggcgctccat ctttttcatt tggagcaata tctttttctg ctaacacatt accttcttta
      721 tcaacaagtt gagctttgtg acctgtacct gctaactcgt ggatgaacac tttcccctta
      781 accgttgtgt caacatcgta tacttcttct aattcaggct ttccaatata tggattggtg
      841 tccccgctct cttctttatc atcaggattt ccgtcaccat caatatcctg caaataatag
      901 taacctgttc cataagtgtt ctgaattagt tttttattag tatccgataa ccaacaatca
      961 aagatgaaat cttctccaaa cggttcattc ccttcaactt gtgcggctgt tttcatttct
     1021 tttaagattt catctaatgg tttagtcaac tgtaaaacgt aacgaacaac aaccgggcgt
     1081 ggacttgcat tagcaaaatc aataagtttg gtaagatcat tatcagtaat tgaacctaca
     1141 ccataatttt catgatcttt gcgccgttca attgctaaat cagccacttt tttccctgat
     1201 tcaaaagaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1261 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1321 gaagctgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1381 ttagcacctg tggatcctga accatctttt gtttgagtat taggttcctc atattttgca
     1441 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1501 aaatcatctg aatctgttaa aaagtagcct gtactatcaa tacctggtac aattttatca
     1561 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1621 atgcctatct ctttaaaaat ttcatctaag ctcttttcaa acgtaattac cccattagga
     1681 gcagtttgtg tatcagttgt ttcagcccca gcaaataatc catcacttgc acgaatataa
     1741 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1801 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1861 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1921 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     1981 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2041 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtggggtg
     2101 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccagca
     2161 ccaaccaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2221 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2281 tcccttaata gttattttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2341 gaataggaat cttactaaac ttatgttaac taatttactt aaaaaatttc atgcacatta
     2401 caacaaaaaa agtacatttc ttcatgtttt tcggatattt gtgcttttta accattcagt
     2461 agctgaaaac atataaaaag atatgtatgt attctttctg aaattaagtt catttctatg
     2521 cgatgaagca tgttttcaaa atattactct ttcttagatt aaacttcaga gtattcaaat
     2581 agcggaataa ggagccttat cccgcattac tgaatgagac tgtgacataa gtaaaaaggt
     2641 gacttcaaat tccttcttcg gaatttgaaa tcaccttctt tataattata aagtatcggt
     2701 ttcacagcat ttctgaatga ttcctagaat cttaaacgaa tgattggagt tatcaacatt
     2761 ttttcactcg tttttagcga aacaaaaaat gacatttgtc acagcctcat taaattattg
     2821 attctttttc tttataattg aattgtccat atttaaagtg tctagtactc tacatgaata
     2881 attaattgct ttcactcaaa tacttataat ctattaactt gtagttgttt aacttttctg
     2941 aaaaagttag acccacgtaa taatcttccc agctttctct ttcaattaac tgatccaatt
     3001 tttgataatc cataaattca tcatgtatta aaaagaataa ataacttgat attttagcat
     3061 ctagcttaat cagattaaat aatgtttgct taaaattgct accattaata tgactgatag
     3121 attctctagc ttcttcacat aaacttttta ctttattaat tactactttg tcatattcat
     3181 ttaacacact attattacca ttacttagac gctcagattc tacgaaacaa ctcaaatcag
     3241 aaatttccca aaaaaatttt ttgttaaaat ccaatttcct caactcctcc aaactacgta
     3301 aatgatatag tctcataata aaataaaacc tctcagctaa tgttgttgaa attgtccact
     3361 aaacctaatt gatattgctt aggagataca cctgcgtact ttttgaatac tctcgaaaag
     3421 tgtgaagaat ctgaaaatcc taaacctaaa gaaacttcac tgatagtatg gtttgatttc
     3481 aacattattt tagccgtaga aatttttcgc ttagagatat aattataaat cgtaatatgc
     3541 atttcattct taaagctttc tcttaattta gtttcactta cagaaaaata attagctatt
     3601 tcctttacag taattctttt atagatattt aagccgatga attgaacgac agaagaaatt
     3661 aagggagaaa gatgctctat cttagttttt ccgatttcct tagtataata aacaatccca
     3721 gaatccctca cttttaagac ctcaggtaac gatacagcta attcgttttc ttgtatcaaa
     3781 gcatctctac tttgatacgc ttctattata tccattccta atgttataga cgtttgtgct
     3841 aacttttcaa aaacaatgat agaataattt ttttcagacc gaatcgtatc tccactaaca
     3901 cttggaatta ttccattact cagattaaaa accatgtttt ctaaatttcg aatatctcca
     3961 tttttaacat attccagtat tttattttca taaagaaaca gatatatttc tggatcgtaa
     4021 ttttgtgata acagattatc tattttgatt tgctcgatag ttttacttag attttctgta
     4081 tattcaatta acggttcatg gaatagatct tctatttttc cagtaaaaaa ataatgaact
     4141 aaaatcagaa tatctcgaat gtctcctaaa gaatacaaag tcaaattttg caatgaatta
     4201 tagagtcgtt ctctatcagc cattgcaaca ttcaaattgt tcatttttag tttaaaaaaa
     4261 ctttatcaat attatttgct ctaaatggac caaataagta atatctggtt ttaaacatgt
     4321 atagaagaaa catctcatta aaatcaccag taaagaaatg gaaatcttta gtttttttaa
     4381 tattatcagt tagtaacttt ttataatcat aaaaaaaata agtagttcta tctgagcgat
     4441 actcttttat aatactgaat tcggaattaa aaaccacgat aggtaacttt aaacaaacat
     4501 gaagagactt taataagact tctttatctg aaaacacttt tgtttctctc tttcctttct
     4561 acatcattaa atagtatttt atacgttatc taaaatacta ttcctctgtc aaaataagct
     4621 aacttacttc attataaaat atccacttat cgctttcatg tatattccac cgtaaaaagt
     4681 acattttatc accgagaact catcattttt catcatgatg aatactattt acatatatct
     4741 agttcaaaga caataattat tatgatccgt tattatctaa gcactataca gataatagga
     4801 atttttcgtt tctaaatatt ccaatttggg aatccaataa aaattttcgt tcaaatacgt
     4861 gtctattcga actcttttct agttgttaat tatgaagggg gaagaaataa aaaatacaat
     4921 ctatacacga ataagaatat tatccaaaag gaggttttag aaaagattta ttatacgtaa
     4981 aaagctcaag acattttctt agccataagg acatgtttga tatttaagaa gatatatgaa
     5041 ttttcttttc taagtataaa gataactatc cattatcaac taaaaaaaca tttttgaaaa
     5101 taaacatcag cagtcctatc aatgcatgtg agcttataga agttattcgc agcgcagcat
     5161 aattgcatta gcttcttttc atgttttttg cctcttttcc ctttaaatct taatggagga
     5221 ggtgtgcaat atgtcagata acgacgaacg cgtaaatgcc cagttgattc gattctttga
     5281 aaaggtcatt ttgaacaccg ctaatactta ttataaaaaa caagaagaaa ttcaaaaaca
     5341 tgaacaactt gatcaactcc caccatattt gtttactaaa gatactataa aatttaaaca
     5401 accgattaat gttttaaatg tgactctcct tgttgaagat ataaaattag caaaaatcct
     5461 tcctttgttg aaagaacctg aacaaatttt tcttatcgaa aaatttatct ttgataaaac
     5521 tgataaagaa attggaaagg ttctggggat tacaagacag ggtgcgacaa atttaaaaca
     5581 tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata actaattttg
     5641 tatgcttctt tgctcgttct cctccttccc aaagaaatag attataagtc catgggaaga
     5701 aggtagattt atgaattctt taaaagaaga tttcatttta gcaaaggctg gaaatgaaga
     5761 agctgttgag gcaattctca aaagatttag ctctttgatt cataagcaat cctggagaac
     5821 tggaaaatat gatcaagatt gttatcaaga atgtatgctt gcaatatatc tagctatctc
     5881 gaaattcgaa attaaagaat aactcaacta agggagtctg tgacataagt aaaaagatag
     5941 tttcaaattt cgaacaataa atttgaaact atcttcttta taattataaa gtatcgattt
     6001 tacagcgttc tataatgatt catagaatct aaaacgaatg attttaatta tcaacgtttt
     6061 ttaattcgtt tttagcttaa aaataacttt tgtcacagtc tcactcctaa aattacttta
     6121 tttacgtatg aagtgggcag gaggtcgaat ccagaactgg gctatggtac ttcaacgagg
     6181 acttctcctc tagaattgaa aagcatgcga tttaccttcc gtaacgacgg tagatttatt
     6241 caactatgtg tccaatcaaa atttgtctga tttcaaaaat agtcaagaga attttggttg
     6301 ttaaaaactc ttatctatca acttccacag tttagttgac aaaccctgat actaagttgg
     6361 gctatgatac acttttcttg actatcagtt acgttaccgg aaggaatgaa ctctattgag
     6421 aaaaacatat gatcgtaaat ttaaactaaa gatttcacag gatatccttg agaaaaaagt
     6481 aactaccaag aaaattgctg aagaatacaa tatctctcgt ccaacaattt cccgatgggt
     6541 ttcagaatat cgtcgatacg ggaaaaatgc ttttgctgga caaggaaaaa gattacctga
     6601 taaagcagat ttctacattc ttgaacagga aaataaacga ctaaaagagg aagacgagtg
     6661 ttctacgaac acaaagatcg atacggatct ccagggatca ctcaaaaact ttacgatgaa
     6721 ggaatcgaaa tcaataaacg tgttgtagct gttcttatgc gtgaaatgaa tttatgcaca
     6781 agaggatttc atcgacgcaa atcttctcat ggtagagaaa aaacaatcaa agaaatggta
     6841 aaaaaatgtt gaatcgataa tttgaacaga accaaattga tgctgtttgg gtgatggata
     6901 ttacttacat tccatgtaat gacggtcgcc tctatttgtc cacctatatt gacttagcaa
     6961 ctcgtattct acgttactat atggtagatt cacacatgaa aaaagagatt gtcgtccgtc
     7021 cattacaaat ttattaagga gaattgccta cggtaattca ttccgataga ggtagccagc
     7081 atcggtcttt tatttatcaa gagctgttga acgaccacca catcacacat tcagtgagcc
     7141 aaactgggac tcctgttgac aatgcagtaa ttgaagcgtt tcatcgatca atcaaatgag
     7201 aattaatcga ctccaacaaa tataaaagta aaatagagat gaaggtgtta atccaagatt
     7261 atttagaaga ctactaccca aacaaaagaa tccatacaaa atttatgatg actccttgac
     7321 aatttgaagc gaagaaaata agggatctat aatatctagt gttggtgacg ccttctgttg
     7381 ccaatacttt ttcttttttc taataaacgc aaacagacac cttaaaatcc tttagaataa
     7441 agtcgacaaa aaccattcaa agtagtgttt caagatgtcc tattcagagt ttaccaaaga
     7501 gttactagat attctagacc taaatcttac ctttcatgag gatgcctttc gcaaagagcg
     7561 catcaatgac gaaacatgtt ttgcttttga tggcacattg acctatcaac cggaggaatg
     7621 ctttcatcgc cactatcaaa atgaacaaac gatcattaaa tagggctgga aaaaagtatc
     7681 catcttattg aatgatgtca gtaactacaa gaccattctg cggattaaca aacagcgctt
     7741 caaatgtaaa cactgtggaa agactttttt agcagaagat tcagttagtg atcgtcgctg
     7801 ctccattgct cgcagagtca aacaagccat tcttgagcta ttaagcgaac ctctttctat
     7861 gtctttgatc gcacgtatga agcacatttc tccgaccact gtcattcgaa tacttcgcag
     7921 ccttcggcct aaaaccattt ctttgaacca gctgttacca gaagtggtgt gtttcgatga
     7981 attcaaatca gtgaaaaatg tctcgggagc catgagcttt gtcatgatgg acggcaagac
     8041 ccatcaactg attgatattg tggaaaatcg gcaactcaat cctttacgcg gctatttctt
     8101 gcgctaccct agaaaagtcc gtgaacaagt acgtctagtg gtttcagatt tctatacacc
     8161 ctatcgcaca ttggtgaaag agcgttttcc gaatgcccga atcgtcgccg atcgctttca
     8221 tattagccaa cacatcggtc gggcctttac caatcaccga attcaagtaa tgaagacctt
     8281 taaaaaaagg gatcgtcggt cgaagcactt aaagaaatac tggagactac ttcaaaagaa
     8341 tgcgtgggaa ttgaagggcc agcatcgcta ctggcgtccg tcatttcgag atcatctgac
     8401 agaagcggag atagtcgatc ggctattatc ttatgatgac tccttaaagc gaggctacga
     8461 agtctaccag gattttcttt ccgctatcag aagacaagct gttccaaaat tcgtcgcgct
     8521 cctaaaagaa gactacaagg agttgccaga gcactaccaa ccagtgttca cgaccttcaa
     8581 gaaatatcga acagaaatca aacgagcgtt gcgcgttccc tattccaacg gccctataga
     8641 atgtttgaac aaccatatca aagtactaaa acgaattgcc tatggcttta gaaattttca
     8701 aaactaccga gaacgaatct ttttatatcg agaaaaatat ttcaagaaaa ctaagaacac
     8761 tacccaactg actaaagcca gaacaacaac acggctagac aagatagctg tctagccgtg
     8821 tgagtatctc gattattcta ttgaatttct tcaccaacac tcattgacga agagccaaaa
     8881 taagtaatct aaccgactgt taactaaacc attgcaggtc ccgttaaaga tacttgtgcc
     8941 tgttgtcacc gcttcttttt cttgtccaca agcgcttaac acacttaata aagcccctgc
     9001 tattattaat aataatatct ttttcttatt aaaaacctcc tcatctattt ccagattagt
     9061 aaatgtagta atctgtgctt tcttttttct caatactaat aactaactta tggggtaaac
     9121 aaatactcgt ttgaccgggt tttgagatcc atccagttct aaccgcgatt tgatcaggac
     9181 tattatcttc tttaactcga attcttccat ctttaatctc aacaatatta tattgtccct
     9241 tcgcaggatg ataattcacg agtttatgat tgatcttatc caaatcgaag cgatccattt
     9301 ccttgccatc aattcgaacg atggcatatt tgatagcatc ttcagttgtt tcattctcct
     9361 tttctataga gaatacaaat aagggaataa aagaggtaat aatcaaaatg ccaataatta
     9421 tgacatcgcc tatcttgaca ccagcttttc ttaaaaattt cattaacgat atctggctaa
     9481 acatattaga ctttttccat ggaaatggtg aaatttttcg gaaattatct gcattaagag
     9541 aatcagttaa acaaccctca agttgttcct taatacattg ttgatccatc ttcataccaa
     9601 taaaaactag tttattaatg cgttcaccaa acaacggatg ccaggcttcc ttcaattcgg
     9661 gatttttttg tataatcatt tgacactcaa ttttaggtaa actagctacc caataattta
     9721 atgattcaat acttttatag ctacccgatg tttcaaagat cgtcgaaaaa tcactatgtt
     9781 gggcaaacca aagaaaccct tttgctcttg taatattgcc aggaaaattt ttatccgtaa
     9841 gatgggcaaa tttttgtgcg tcaaggagta accgatttcg atagataaaa cttgagatac
     9901 catattcttc tgtttcagga atatgatttt gatagccaag ctctaactct ttgaaccagc
     9961 ccactgaata ggaagtctca tctatattaa aaagatttgt atttagaatt ttcgataagt
    10021 ctacttcacc tttaattgtc ctaattattt tggcattgga ctgtaactta gcaattagac
    10081 cgttaatttt gtaaatcgtc ttggttgaca ctaagtcact attatttaaa agtaatatgt
    10141 tacaacactc gaattgatca attaacaagc cacgaatatc ctgttcttct tcaactacat
    10201 taccttcagc ttttctttcc tgaatctttt cacccgtttc gaaattatcc caaaaacgtt
    10261 ttacatccac tactataata atggcaccaa tctctaatcg ttgggtcaaa tcaatgtcta
    10321 aagggttttt agctaatata attgcttgaa taattggaat tggtttgctg attcctgaag
    10381 cttcaataac aatttgattc aagtcagaaa attgcactaa ttgatctagt tcaacaatca
    10441 aatcttcgcg taatgtacaa caaatgcatc cattcggcat cgaaacaagt ttttctccag
    10501 ttcttttaaa acctttcttg tcgactaata ccccatcaac atttacttcc cctatgtcat
    10561 ttacaatgac agcaatttcc tttccgtgat caccgtacag aatatgattt agaagtatcg
    10621 tttttcctga accaagatag ccagttaaga ttgtaatagg tatttttttc atagggaacc
    10681 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
    10741 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
    10801 tcgtcatctt actatactcg aacgagaaag aatctttctg cttcacgaag aaggattttc
    10861 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
    10921 aagaaacaag aaaaaaacta ttcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
    10981 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
    11041 ttatttgtcg attttcagtg gtcgccagag gaaatctcga atcgtttgaa gcatgaacat
    11101 atggactttt caattagttt tatcacgatc taccgtgcaa tttgcaatga tcttttcgat
    11161 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
    11221 acaagacata caaaaaatca tgtcgagtct cgtggaaaga tttgccttac tcattcgatc
    11281 catggccgtc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
    11341 gtagctggca aaactggtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
    11401 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
    11461 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
    11521 gaattctcca atcatttcgc agttacagaa gcattgaata atatgccctt ttattttcca
    11581 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
    11641 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
    11701 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
    11761 ttgataaagt gttgcgcttg atttgacaat tcaagacata ataaaaagca gatcaaatcc
    11821 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
    11881 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
    11941 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
    12001 tgtactccca tttaatctca tttgctttgc aaatcgataa cgccgataag catcaatatt
    12061 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa aattggattt
    12121 taatgagcca tcatttcttg agcaatttca tgtttagaca atgaagctgg atagaaagta
    12181 ggccaattat gcatttcatt atagagtttt tcttgacttt ctccaccaag gaaaatatgg
    12241 aaatgctctg ccttacttgg tgcaattcca tgatcactaa attgaatata tttaaaacga
    12301 ccagcacctg catcatcagt ttcaaaatta aaacgaacac cacggtttcc tttttcataa
    12361 ttcaaaattt tgtatccaac atatttgtat gtgtattgat gatgttcacc gttgactaca
    12421 aaatcaatgg tgttgtcttt aatgttgata gtatcaatat ctgtcttata gccagtagta
    12481 taataatctt tgtactcggc agctgccatg tctttattga gttttgcttt gtaatcgaaa
    12541 acttcatcca aaattccatc ttttaacaac ggataaacag attgccattc gcctgtataa
    12601 tcactcaatt cgcgatcctt cacatcggca tctttaaagt acccattagc aactgtcttt
    12661 tcatccttcg cttctttttc tggaactacc tcttcaccag caaccatagt tgttttttct
    12721 aacgctttta gattgtcttc cattactgaa acataatctt caccattatc catttgttct
    12781 tttgtaagac tttcaagagg attcagtact tccaatttta tcccagcttc gttggccaaa
    12841 gtttttgcaa ttttatcatt agcattcttt tcaaagtaaa tataattgat cttatttttt
    12901 ttaacatact cttttaattc agctaatcga ccagaagatg gctcttcttc aggacttagt
    12961 ccagcaatag gaacttgttt caatccataa tccaaagcta aatatccaaa ggctgcgtgt
    13021 tgcgtcacaa aacttttttg tttcgcttct ttaagactag tggtatagtc agcatccaac
    13081 cgtttcagtt tagtcaaata cttttcagca tttgtctcaa atacttttgc ttttttcgga
    13141 tacaatttaa ctaactgatc cttgatattt gaaacttcct taattgccat tttgggtgaa
    13201 acccacgtat gaggatctag ttcatgatgg tgatcttctt ctccgtgatc atgatcttct
    13261 tcttcactac ctggcaataa aatcatgtct tttgttcctt ctactacatt aggcccagct
    13321 ttcttccaac tttctttagc ttttggtacc catgattcca tgttttcgtt atgatataca
    13381 aaaacatcag catcatgagc ttttgccata tccttagctg agggctcata gtcatgaggt
    13441 tctgatcccg ctggaaccat taaatccacg ttcgcttcat cgccgacgat gtttttggtg
    13501 aaatcataca ttggatagaa tgttgttaca atttctaatt ttccatcttt atcattcgat
    13561 acttttgcat cattagtgct ggagcaagct cccaataatc ctagagctgc tatcccaata
    13621 agtcctacac tgattttctt cattcttttt ccttccttaa ttatgctaat ttcttcattt
    13681 tatttcgttt atgttctttg ataattttta atgccctttt tctagtttta atattcgggc
    13741 ttttaagtcg tcgatatgca ctagatatat ccgttttctc cattagaaat tacccccaat
    13801 cactacttat cattatttgc tttccgccag taatttatca aaactctgtt tgatcctttc
    13861 ttcatccaac atttttccga ttagaataat agtggtttgg tctttttgtc gagtggtgta
    13921 ttgaaaatta acctgttcgt ttacctcttg catggcaact ataaaatcct gctcttgtaa
    13981 agcaatcaat cctttaaaac gatacaggct cccttggttg gttaaaatca gccagtcaat
    14041 ccattggagt aaaaaatctt tttttatgtc ttgatctgaa gttaagagaa ttgatttaaa
    14101 ctcatgtact tgatggtgtt gatgatagta tttgccatta tagtgatttt ctgatgaatc
    14161 acttttaaaa actaagggat gattaaattt tttcaaatta taaaaatcct ttttttgaat
    14221 cgtttcacta tgtgtgaaca ttcgaatatc ggataaaggg ttaatacttt tgatttctct
    14281 ctgtaatttt tttagtgcag ataaattcaa gttttgtttt ctagacacaa aaatgcgatc
    14341 tgccatgaca agttgcttaa gggcttgtgg ttctctttca ataagttcaa aactgtcact
    14401 atcaataaca gtcaataaac tatcgatata tactcttcct cttagttgag gcgctgttaa
    14461 aagtgtttga atgattggtt ggggatctgc tatacctgta gtttcaatga tgatttgtga
    14521 aattggttgt tgatgttctt ctattgtttc cagtaaagaa atcaatattg ctaataaatc
    14581 actgcgaaga ctgcaacaca tacatccatt atttagttgt aacacccgtt cctcgctatg
    14641 aactaataat ttgtgatcaa tcccaacttc accaaactca ttttcaatta taataatttc
    14701 ttccctgggg tagggtgaga cttgcaaggc ttgattgatt agcgttgttt ttccagcccc
    14761 taaaaaccca gaaacgattg taactggtat gcccattttg tcaccttttt accacttagc
    14821 tatttcactt ctttgaaaat tgcccgtctg cgcaattttg gcgaatactt ttttaattct
    14881 aaccgttcag ggttattccg tttatttttg ctggtgagat acagacgttc tccagtttcg
    14941 acacattcca aaataatatt ttgacgcata aatcttcctc cttcaatact tatcgatctt
    15001 caagatatgc ttgaatttgt tgtgcatctt caaaagttaa ctcgccagat tccaattgtg
    15061 aaactaaatt ttctttcata tcaacaggta tctcccaata accatcgata cattgaaata
    15121 actcctcgtc atactcttca aaaattggat agattcttaa aaaatcatca aatgataagc
    15181 cttggtcctc atagtaatct ttgactaatc cattttcaat tgcctgttgg gtcggtaaac
    15241 ccgtttcagt aataattcct ctctctacca tcgaacgata aaaagtgcat ttatctagcg
    15301 attgctgggt cgtttcaaga taatacttta atccttcttc aactaaaggt gggtaaataa
    15361 tttccatttt gattccctcc taaaagttat atattaaact attttgaagc tcctttaatt
    15421 actttctttc cattatagta cccttttaaa gatacatgat ggctacgtct ataatcacca
    15481 ttcgcttcgt caaatgaaat ttctggtttt actacagttt gatgagttct tcttaaccgt
    15541 ttcttcgcct tagatgtttt tcttgctggt actgccatga tatttcctcc ttttaccaac
    15601 ttgctttttt tactccagga atcaaccctt gatgggcaag ttctctaaac ttaatacggg
    15661 acataccgaa ctttcgcata taccctcttg gacgaccatc cgtctgatca cgaagcctca
    15721 gacgattcgg atttgaatct cttggcaatt tagcgagagc ggtgcgatct cctgcggctt
    15781 ttaattcctg acgtttatct gcatactttt caatcatcgc catttgtttc tttgctttag
    15841 caattttcga cttttttgcc atataccttt atactccttt tattttgatt tagacatctc
    15901 aaatcgtaat cgttacgttt tgacactgat actttaccaa caagagttgc tcttgtcaac
    15961 aataaataac atgaaataaa actcatatga atagataact atttgaaaac gaatttatcg
    16021 gtacatagag ataatcaaat catttaaaag aatatgcagt ttaagctctg aaaaataaga
    16081 attcactttt attagtccaa tcaaacacaa ataccgtttt aagtagcttt tcctctactt
    16141 aaaacggcaa tatgaaagaa actataactt tttattcaat cttttatgtt taactggttt
    16201 atcgccaatt ttttaaaact ttgattattc cttatattat aagaatagac attaagtgaa
    16261 ctaattcaat catactgatt ctttcgtgta ttcaaaatta gatgctgttt aataaaatta
    16321 ttctttttga aaaagaatta taactatatc ccaaaaattg taggttaatt taaagcctat
    16381 ttcatcatcg tgattgagct tctttttcat agacgaattt ctcagatagt ttagttttct
    16441 ttatgagatt tttgtatatt tctgaccttc gatacaactc actatgagta ccttgatcaa
    16501 ctacttttcc ttgatccatc actacaattt tatttacctt ttcaatagac ttcaagcgat
    16561 gcgatataat tagtactgtc ttatcttgta ttaaacgatt taaactttcc tgaatacgtt
    16621 tttcattttc cgcatctaaa ctggcagtaa tttcatctaa aattaaaatt ggcgcatttt
    16681 tcaaaaaagc ccgtgctatg gataggcgtt gtcgctctcc tccagaaagt gaacttccgt
    16741 tttctccgac caatgtatga taaccgtcag gtagtttttc aataaagtct tcgcagttag
    16801 ctaaacgagc tgcttttttc acttcctcat ctgacgcttg actatttcca atacgtatat
    16861 tttccaaaat acttgtatta aacaaagtta cctcttgaaa aacaatagcg attttgctaa
    16921 acaaagaagc tggagataca cgtttaatat catacccatc aattaaaata cagccttcat
    16981 cataatcata cagtctagac actaatttca agatactagt tttcccggaa ccactagcac
    17041 ctactaacgc agtcacttct ccttgtttag ccgtaaaaga gatatgatct aaaattgggg
    17101 tattgttatc atatgagaaa gagacatctc gcaactcaat gtcaaaagat ttcagaggac
    17161 tatctgatcc ctcttggata ctggtttcct tcatagctct aattcgctgt attttaggag
    17221 ctaaataaaa tatttcaagc actgcttctt tcatagaatc gaaggaatcc tttattttta
    17281 ttgcggctag taagtaacca acgacgtaga gtatagtcac ttcacccgtt aacagtaagt
    17341 gaacacctac tagaatgact actgctaaac taacatatga gaaaatagag gataaggcca
    17401 tgactgaaaa agtacttaat tctaccttta aatgaatcct ttcactctct tccatttttt
    17461 tgaaaagtct gtcttgaact tttttagata gattaaagct attaatctct tgctgcaatt
    17521 caatagtttc ttgaaattct tccgagtttt ctctcaaagt atcgtaatat ttagtattgg
    17581 ctttcgtttg ggatttcttt gataacaaga ttaagacaaa actaaataac gttggcaaaa
    17641 taacagctaa tcccattttg acattaccaa ccaaaagcat cactgaaata aaagggaaaa
    17701 acagagccat accgccggct ttaggtattg catgactcat cgcatgctca ataccttcaa
    17761 cgtcagacat gatagtttga gataaatctg ataaattatg ttttgaaaaa taggataatg
    17821 gtaaatttga caaatcgtct gcaatttgca ctcttaaatg cgcactttct ttataagtac
    17881 tattatataa gttttcatac tccctatcta acaaccaata catgaaaagc aaagtaacaa
    17941 acgatactgc aaaataaagc caacggggct ttgcattttc taaaactaat tcgtctatca
    18001 gcatcattat aatgaatgct ggtaccatat taatgcagta tacaaaaaaa ctagaaatag
    18061 aagctttagt taaagcttct gcgccctgat cagttaaagc aaattttttt ttataaaaat
    18121 ttttcattgt caagcctcca atcatttgca ttctcataat tagtgaccaa ttgtttatac
    18181 actcgatgtt tagccattaa ttcattatga tttccacgtt ctactatttt tccttctgac
    18241 aagacaagaa tttcatctac agatttaatg ctggataatc gatgagctat cataataact
    18301 gttttttctt tcatcaaata ttgaaaagcc ttttgtagtt catactcatt atctggatca
    18361 atagatgcac tggcttcatc cataataaca atctttgcat cttttaaaat tgctctggca
    18421 atagctatac gttgtttttc tcctcctgac agataaactc ctttactacc aattaaggta
    18481 tgctctcttt cgggaaattt ttctaaaatc gattcgcaac cggctaatct tagcgcgtca
    18541 aatactttac ttgctggcgc ttgaggattt gctatagaaa cgttatcgta aatactctga
    18601 ttgaatagtt tcgtatcttg aaagacaaaa gcaattgtgt taataattgt gtcttttgaa
    18661 tagtgattta aaggcttacc accaatttta atctgtccct tatccacatt gtagaaacct
    18721 gaaattagtt tagctatcgt actctttccg cttcctgatt ttcctactaa tgcataaatt
    18781 cttttttgtt ctaaaactaa gttgaaattt tctaaaacac actcttcttt gtatgaaaag
    18841 ctgacatttt caaatgcaat gtcacaattt ttaatctgtg tctcgttccc atattttagt
    18901 tggtcttgct tcatttctaa ataaagggag tctagtgttt cgactgcata tcttgcttca
    18961 aacaagtgca tacttacata cattattctc atgaaagaaa caaaaataat tccacttaaa
    19021 aaaaacaaca tcaacaagtc aacagctaat atcttgggag tggtaagaga agttataaaa
    19081 aaggttatag gaactatcaa aatgcaaact atgccaaaaa atagccattg aaaaagaaca
    19141 aaaggtgttt tcccactcaa agaatactta tatgcaaact tagcataatc gttaattgct
    19201 ttattcaagg ctttaaatga tgttacttta gcaccaaata tctttataac ttgaattccg
    19261 cggatatatt ctaccgtttc agagcttaac acatctaacg attcttgata tttttgaata
    19321 aaatttgtat tctctgtcat tttctttaac aagaatacac caattactaa catggcgatt
    19381 agaaccaatc caattttaaa gttaatgaaa aagcctaagg caactgataa aacaggtgtt
    19441 actatggctt gagcactatc tggaatcaag tgagcaattg ccatatgtgt tttagccgcg
    19501 ttgtcatcaa ttgtctttcg aatatatccc gaagaattta aatcaaaaaa acgaaaactt
    19561 gcttctgtta aaccgctaat tccctttttt ctcaaattag tctctaagcg aaacccaagg
    19621 atatgagaaa ataagccaga aaaaatataa aataaagctc ctaaagttaa ccaagcaaca
    19681 gtttgaaccg cataactctt agctaaatat tcatctccta caataattag agactgaaga
    19741 aatttgtaaa tactgtaata tccatagact gttaatacga cagaaaaatc agaaaataaa
    19801 gtggctaacc atccgtagta tttcatttta gggacataac taaataattt tttgtatact
    19861 ttcatttttt cctcccccgc attcaatttc ttctcttatt cgtttacaac tgttaatgct
    19921 ttccgtaata gcgtaaatta gagatgtaca aacagataga aggtaaacta cgttctattt
    19981 tttgtatttt tttaagactt ttcttccaat caatacacca atcatagata aacttgctac
    20041 aactaacact gaaataattc cccatatacc caccgcgtag tggatcattg catccattgt
    20101 tgcagcagat tgtcctctat ctatccagtc ttgacgaaaa cgatctgtaa agaaccatat
    20161 gggaatccac tgtccggcag cactgcctag ttgcattaga acccaagaca caacttgagg
    20221 aattgctcga tcatatccaa atacagatag aataatatca gctaagatcg ccatactaat
    20281 cgaactgata aaccaaggta agtacgcccc gcccattaac gtaaaaaata acaataaaac
    20341 aattgtgtaa atagtaaaaa ttccttttct agggtagtta tagctaatat aaacaaatat
    20401 gattccagat aataatccaa aaatccctgg ggatatgctg tgaccaaacg ccccaccaat
    20461 actactaacc attattgaaa aaaagtaaat tactagggaa ataactgtag ctaaaccaat
    20521 aaaaatataa tcttttgttt tcatatatat tctcctcaat tctatttcgt tatgtcatta
    20581 aaaatctgtt ctatcaaagt tgaatcttct actctaagtt ttatatcttt ttttattcca
    20641 ccatttttta aataaataat tctattgcat gttttataaa gaaattccgg atcatgagtg
    20701 gctataacta ctgcaccctt ttcttttaag tctttaataa ggtcagcaat cctttccata
    20761 ttgatataat ccaacccact tgtaggttca tcaaatagaa ataaattagt ttttgacaat
    20821 gaagctatag aaaccaataa tctttgtttt tctccaccgg ataaatcaaa cggtaattga
    20881 tctttcattt tataaagttc catttttttt aaaatttttt cttgctgatc tttactaact
    20941 atttcattcc ccagggctaa ctcgctcctc actgattctg tgaaaaactg gtaatccatt
    21001 tcttgcatta ctaaaaacgg cgatgaaatt tttttatttt cgattatctt tcctttggta
    21061 gggcgaataa tcttcatgag tattcttagt aaggttgttt tccccacacc gtttttccct
    21121 accaaaccaa taacatctcc aactttgaca tcaaaattta tgtcttttag aatattttca
    21181 taagtaattt cttcaacttt taatacatct gcacttacct tttcgatata gggaacttca
    21241 atcgaactat taaaaatgtc aaatttcctt aatgcgttat tgttttcagt ttttaacaac
    21301 tgaatagttg tagtttttac agttctattt ttaacaaata gaacttgatc aattaattct
    21361 ttcaaatagt aaaaacgatg ttcagctata acaatagtaa atcctttatt ttttaaatca
    21421 caaagtaagt cagcaagttt cttagtcgct ttgaagtcca aatttgaaga cggttcatcc
    21481 aatataatta atttagagtt tagcgataaa ctacatccaa tagaaatttt ctgccgttca
    21541 ccacttgata gcgaaaaaat gtttttatct aatatatttg aaagatctaa taattcagct
    21601 aattcattga ttcttttatc catatgctct tttgtaaatc caaagttttc catcgaaaat
    21661 actaactcac tcgttgtatt tgttgtaaag aattgtcctc taggatcttg acttacgtag
    21721 ccaatatttt ttgatatact ttcttgtgtt aaggattgta gcgagttatt ttcaaataaa
    21781 atttccccaa ccaattttcc gtcataaagt cttggaataa gtccattcat taactttaat
    21841 agtgtggatt tcccactccc agaagaacca gtaatcaatg taagactgcc tttttttatt
    21901 gaaaaattaa ggtcaacaag cgcttgttcc ttaacatcct tatatgaaaa agaaacattg
    21961 ttaaattcaa acaattcttt cacctcaaat caaaatactt aagaaaaaaa tagtaacgga
    22021 aaacaggatg atatagtcta ataagctcat gtttgtttta tagtaagaac ttcttttcac
    22081 aggagattct atcccctttg ttattgcatt agcggtcatt tcttcagcaa tcatagttgc
    22141 acgtataaga acgggaacta acagaaattc caaatattgc agaggctgaa aaaaagacaa
    22201 gcgaatgttt ctcattttta aagattcttt aatcattctt atttcagaac gataagtcgg
    22261 aaagaatctg atcactactg taatacttaa cattattttt ttcggtaaat gtattttttc
    22321 taaagaggat aataattcat tgctagtata gacactaacc aacaaccatg agatcattac
    22381 gaccggcaac attcgaaata caatatataa ggatgtccca aaaaatatag taaaaaactc
    22441 tatcttgata gcatcaataa ttttcattac taaaaacaga actgaataaa tcaagatgaa
    22501 ataaatacat gtctttattt tacgaaacat caatactaaa actgtagcaa taatgaaaca
    22561 ccccacttga aatgtatttc cctttcctaa aaaaataatg accggaaaaa aaatatttaa
    22621 agtaatcaag gttaacggat tgatttttaa cactctttca cctccaaaaa ataagatcgc
    22681 actgttatct taagctgata aaaatgcacc gttattcaga taacagtgcg atcttatcaa
    22741 aaagcataac tgagaacaat tctcaatgca agcttttttt aattaactca gtaattcaat
    22801 ccacccagga acagaaaatt gatacaatct tctggttaat agcatagtct tttcttttga
    22861 atagctatgc ttcaatatat catagaatgt agcgtagaat gagtaaatgt agaagtggat
    22921 ttcttcttca ttaaagacta aattttgatt gatcattccg atagtcttta acttatctag
    22981 acaacagact gttttttttg tcacaaatga tgtaattttt tcaacaatat cttgatattt
    23041 ggttccagct gattggaata aaaccaaatc gaatatacgt ttattctcaa aaatataatt
    23101 aataaatgga tctaattcat tgaagttctc tctccaactt ttctctatat ctatattttc
    23161 taagtttaag aggtatttgg taaactcttc attatacata ttaataagcg cattaatatg
    23221 cggctgaata atttcttcaa ataacgcttc cttagaagta aaatgtttat aaaaagcacc
    23281 cgtagttacg cctgcggtca agcacagttg ccttatctta gtttgctgaa atccttcttt
    23341 ttcaaaatgg cttagtccac tttctattaa tttttggtga gttgtaatat aatctctggt
    23401 ttctatgggt acttcctcct aataagatga attaactata ttatcttaca caggacttga
    23461 agtttcaatc gttaacgtct attactgaac tcattcctta gagctaaact aatgagaaag
    23521 agcaaaataa ctgatacaaa aagcaatcct acaagaatta atagactcat ctaaatcatt
    23581 caccttttct aaaataaacc gagaaagatt taaaaaaatt atatccagct attaggataa
    23641 gtcctatcat aatcactcca atagccattt tcttatcctc cctaaaaata aagtctttta
    23701 cttaaaaact tttttgtaat cgtcaataaa ttttttccct ttatcagtta attgaaatcc
    23761 tatatctaaa tagtcctcat atctaagttt agtcagcatc tcacttacag atgctggact
    23821 aacacttaga acttttgcta aatcattatt ttttaatttc ttttttcttt ttgataattc
    23881 ctgaattgct agtaaataaa ttagtatagt agttgtttta atttgtacca tacctaccct
    23941 ccaaattatt tcgaaaggcc ttcagcaatt ttatccaggt tccatttcat catcgcatag
    24001 taactatcac catcttgtcc tttttctgca attgaatcag taaaaatcgt tgaatagata
    24061 ggaatattgg tatcttttga tactgttttc attggtctat cgtccacact gctttctacg
    24121 aataaggagg gaacttttgt tgtgcgtaat ttttcaacta agtgttttat ttgatctggt
    24181 gttccttctt cttcagtgtt gatttcccaa atgtaagcag aaggcacatt atacgctttc
    24241 gagaaatatt taaagcatcc ttcacttgta acaatcattt ttttatcatt cggaattgaa
    24301 gcaaatttag atttagcttc tttgtctaga gaatccaatt tttcaatata cttatctaga
    24361 ttttctttat agaatttttt attatcagga tctttttccg ctaactgttt ttcaatattt
    24421 ttagcgtaaa taataccgtt ttctaaattt aaccaagcat ggggatcttc cttccctttc
    24481 tcactctgac cctctaagta aataacatct atgccatcac ttgctgcaaa atagtctttg
    24541 ttttcctctt tgttcgcatt ttttactaat tttgtaaacc aagcatttcc tccagtttcc
    24601 aagttaacac cgttataaaa aatcaaatct gcttttgaag ttttttgaac atcttcaggc
    24661 aaaggttcat attcgtgggg atctttccca ataggtacga tactgtgtaa atcaatttta
    24721 tcttttgcta tattttcagt aatatctgct aaaatcgaat tagtaactac tacctttaat
    24781 ttttcgttcg aagccactgt atctttgtct ttactatttg ttgaacatgc cccgaatata
    24841 aaaagagcaa tcaaaatccc cagacttccc agtactgctt tccattttct catcataact
    24901 ttctctcctt ctttcttaaa aatttttgtt ttggtgagat tagaaaacta attacaaata
    24961 agaatgccgc tgttaaaaca atacttgatc ctgctgctat gttaaaacta taaccaatga
    25021 acaaacctag caatgatgag cacgctccga ctgtcgccga aataaatatc atagttttta
    25081 agctgtttgc atataaatat gctgtagcag ctggtgtaat taacattgca acaattaata
    25141 tagttcccac actttgcata gctgttactg ctactaaagt taatagaatc attaatagat
    25201 aatgataaaa actgacattc atccccattg cttttgccat taatggatca aaagaagtga
    25261 ttaataattc tttaaaaaat agaacaactg taaccaacac taaaacagaa acgccaattg
    25321 taatccactt atcaatatct tgtacagcta aaatatttcc aaataagata tgaaataaat
    25381 ccgttgagct atttgcaact cctataagga taactcctaa tgctaaaaaa gaactgaaag
    25441 taataccaat tgctgtatct ccttttatta cactattgct ttttataaaa gtaataatga
    25501 tagaagctaa tagaccaaat acaatcgcac caataaaaaa attaatacct aaaatataag
    25561 aaattgctac tcctggcaaa acagcatgag aaatagcatc acccataaga gacattcctc
    25621 ttaaaataat aaaacaacct actgttccag aaacaatccc tataactaca gatgtaatta
    25681 gagcattctg taaaaagtga aagtcataca gaccattaat aaaattttga agcatattat
    25741 tcccccttgt atattagagt tagggtttta accttccggt tttgattgga taaccctatg
    25801 aaccatcgtt attttaattt ggtattaact catttctttt gagataatat atttattgga
    25861 ttgagaggct aagccgttcc ccccttgggt cattgaaccc gcactcgaga gactggctcc
    25921 tctctctgat aagtggattg cgtatgagtt agatgttgaa agtccttact ttactccgta
    25981 tctcgtacaa ggtagtgacg cttttcagtt gagtggattt caatccaaaa ttcttttttt
    26041 gaaaggtcag atatacatgt actttttagg cattgatatc ggtaaacgca ctcacgttgc
    26101 ttctatcatg aacgaggaag gaaaggtatt actaaaaggt ttttcatttc ctaacaccac
    26161 tgaaggagca gagtcattaa ttgagcgaat ggtcgactat tccggagcac ccagtgactt
    26221 tgttataggg atggaagcca cggggcacta ttggctgtcc atcttttcat accttcacga
    26281 atcagattat ttgattcacg ttgtgaatcc ccttcaaaca gacggatggc gtaaaggtac
    26341 agaaatacgg aaacgaaaaa acgatattat tgattctgtt ttgattgctg acttaatgcg
    26401 ctatggctca tttgtcgaaa cggtcttatc cgatgaaaat gttttttctt tgaaacaact
    26461 ttctcgttac cgaacttatt tagtaggtac agcgagcgac ttcaaaagaa aaattatagc
    26521 cgtattggat caagtctttc cagaatacgc gacgattttt accaagcagg gcgttttcgg
    26581 aaaagcttct aaagagttat tgctggcgtt tagtgccccg atcgacttag aaaacatttc
    26641 ctcagaaact ttggcccaat acttagctga gttaagcagg aaccgaatca aggcagaaaa
    26701 agcggaccaa ttgaagcaag cagcttctaa ctcctttgga gtaaaatttg ctcaagaagc
    26761 gttcaccttc caactacgtt caatgattga acaattaaaa ttcattgaaa gccaaataaa
    26821 ggaaacggaa agagaaatca agcacataat ggacacttta aattctgtta ttctcacaat
    26881 tcctggaatt ggtcctataa acggtgcgac tattcttggt gagatcggag atattcaaaa
    26941 attttctaac ccgaaaaaac tcgttgctta cgctgggata gacgcttccg tgacacaatc
    27001 agggcaatat gaggcaacgc ataatgttat gagtaaacga gggtctccat atttgcgaaa
    27061 agccttgttt tcggcggctt tagtagcttc tcaatgtgat cctgttttta gtgcgtttta
    27121 ccagaaaaaa gtttccgaag gaaaacatca tctaactgcc ttaggtgcgg tttctcgtaa
    27181 gctttgttac gtgattcatg ctattttgac taaaaacgag ccttatataa ttgtttctga
    27241 ttagctattg aacattcaaa aaaactaatg gtaagaagct tatttgttgt accctttttt
    27301 cggaattatc tgttataaaa tattttttga tttggctaat ttttacttga ctctatatag
    27361 ttagtctctc caataaatat agtatctcca taggcttttt ttaaattctc ttcattaaat
    27421 acagattcta cacttccgtg agcaattaga tttcgattca aaagaataat attatcaaaa
    27481 tacttcttta ccttgcttaa atcatgatgc acaattagca ctgtttttcc ctgatgtttc
    27541 aattctttta acgtatccat aattattcgt tcactaacta agtctatccc tacaaatggt
    27601 tcatctaaaa atatgaaatc cgcattttga gcaagacatc ttgctaaaag tacacgttga
    27661 aattgtcctc cagataattc tcctatttga tgattagaat attttcccat atcgaccttt
    27721 tccaaagcct ttgaaactct ttgccattct gcatttttaa ttctttgaaa aactttcatt
    27781 ccggcatatg ttcccataga tacacattct tttactttta ttggaaaagt aaaatcaata
    27841 tcagcttttt gctctacata tgcaatcttc accagttttt tattgatatc ttcattatta
    27901 atggagacct ctccctgatg agggataata tttaacattg ctttaagcaa tgtagatttt
    27961 ccagcaccat ttggaccaat aatacctgtt aaagcacctt cttgtatttt taaagaaatc
    28021 tcgttcaatg ctaaaaaatc gttataacaa acattaagct ttttcacttc taacataact
    28081 ttctccttct aaatgataat gattatcacg atcatatggt atacaaaaat tatattttag
    28141 tcaaccctaa attttataat ttagattttt ttctgttgct gaagattaga atgacaaaac
    28201 tatttgaaac tacgcgtata gtaagtagct ttcaaaatat ataaaaaagg agcgttctca
    28261 aatgagaaca tgctcctaaa actactttat tggcgtatgg aaaaattata cttaaagtgg
    28321 atagcgggtt gaataagttg ataagcatca aaacatttat aaaaattatt caagactatg
    28381 tctgttccat atacaaatat gaaaatcagt aaactccatt taactttttt cgtagtgtgt
    28441 ctttttatac atgtttatcg ttattaatag tgaataggaa aaaacctatt tttgatcatt
    28501 gacaattaaa tacaattttt gaataacgat ccctgctatt cgagctagaa actcaagtac
    28561 gccatgacct gattagcgac aaatacttag agatttcttt ttgttctggg aaaacaaaat
    28621 gccatgacaa tagcagcaaa taatgatact tccgtaaggc tcgccgtaaa ctggggagag
    28681 gtgaaattcc tatgtgttta cccaaagcaa ttcaaaaatt ctaatctttt ttaggagatg
    28741 attttataaa attgagagtc tacttgaata aaaaacaaac ctgtgagttt ctaggaattg
    28801 ataataatac tttagataag tggattcgta tatataattt tccagtaatc agaattgacg
    28861 gtatagttcg ctttgacata gaggatatca aagattttat gaatacattt aaaacaattt
    28921 gaaaatttct tctcgccgca tatactaaga atagcgaaat atactgcctt actttttaag
    28981 ggagtgagga attttgccta caaaactttc aaatgggaaa tataaaacta atctgaggta
    29041 tccaaaaaaa ttcagagaaa tcactggaat tacatcagaa aagtatcaaa aagtatttcc
    29101 aactaggcaa ttggctatta aagccgaaaa tgcaatgaaa aggaaaattg aaacagtttt
    29161 aagagaggag aatgcaaatt cactagaatt aaaaggaaaa ataaaattta aggaattcta
    29221 tgaatcaaaa tggcttccta gatatgaact aggtcagact actagatcaa aaagagctcc
    29281 aagttacgta acaattagta atactaaaga tatattccga ttgcacatcc ttccaatgtt
    29341 tggtgagtat gcaatgaact atctaaattc aaatactgag ataatatcag atgaattaac
    29401 aaaaaaatcg aaagaatacg caaatataaa aattatcaaa ggatatgtcc gttctatgtt
    29461 tgatattgca gaaatactaa attatattga atttaaccga actaccaaaa ttattcaatg
    29521 tatcactgca cctaaaaaaa ttgctttaga agaaagaagg atacgggaag gtaatcaaac
    29581 attatcgtca gaagagctta ttgcttggat agaagcagta aacactgact tgaataatca
    29641 cttgcttact cttcatgact atactctttt catgcttacc ctatatcttg gtgatagaaa
    29701 aagtgagacg tatgctttgc aatggaaata tatcgacttt gagaaacaaa cggttcgcct
    29761 taaacatgct ttggataaat atcaaaaaaa gaaatttaca aaaggtcgaa aggataccgt
    29821 aattcaagta cccgaaattg taatggcatt actaagcaaa tggaaatcag tgcaagctga
    29881 gcaattgttg agattaaaaa ttaatcaaac accagatcag tatctcttta cctatactaa
    29941 accatccgga gaagtaaatt gccctgttca cgctgattac ctaaactatc gaatcaattc
    30001 aattaaaaga cgacatcctg aattggctca tttatctcca cataagcttc gtcataccta
    30061 tgcaactata gctagacaag gcggagcaaa tatgaatcaa atatctaatg ctttaacaca
    30121 ctcagatatt tctactacaa agatatacgt aaacacacca gatgtagttg ataagactgt
    30181 tttcgaagca tttcaaaaag gattaaagaa ctaggatgaa tgtgttctcg aatgtgttct
    30241 taaactaaaa aaagacactt tccaaataat tgaaaagtgt cttgaaacat tgatatacaa
    30301 agaatattaa cgttttgaaa actgtgaagc tttacgagct tttttaagac ctggtttttt
    30361 acgttcgacc atacgtgcgt cacgagtaag taagccagca cgtttaagag ctaaacggaa
    30421 gtcaggatca acttctagca atgcacgagc gataccatga cggatagctc ctgattgtcc
    30481 agcgtatcct ccgccgttta cgttaacaaa tacgtcatat gcgccttttg tttcagtaac
    30541 agcgaaaggt tgattgatta cttcacgcaa gtcagcatgt ggaatgtatt cttcaacatc
    30601 ttttttattt acagtaattt tgccagttcc tggtactaga cgtacgcgag caactgcgtt
    30661 tttacgacgg cctgtgccga tatattgaac ttgtgccaat gaaattccct cctattagat
    30721 taagtttgtg atgtctaaaa cttctggttg ttgtgctgca tgtggatgtt ctgctccacc
    30781 gtatacgttc aattttgtaa attgtttgcg gcctaaagtg tttttaggaa gcataccttt
    30841 tacagaagtt tcgatcaaac gacgagaatt tttagcacgc aattcgccag cagtgattga
    30901 tttcaatcct cctgggtagt tgctgtgacg gtaataaatt ttgtcagtcg cttttttacc
    30961 tgttaatttc actttgtctg cattgatgac gatgacgaaa tcgccagtat ccaaatgagg
    31021 tgtgaaagtt ggtttatttt taccacgtag tacagatgca acaactgttg aaagacgtcc
    31081 caatggaaca tcagttgcgt ctactacata ccatttacgt tctacttcgc ctggtttggc
    31141 catatatgtt gtacgcacgt tattttcctc caatttaagt tctgatgttt gacatacact
    31201 tcgagtttcc ggggctcttt gtggggcaaa caataccatt taacatatta cccgctaatc
    31261 tagtcaatgt caacgttttt ctgcttgatt gaaaaattta tatgaaactt tacttctttt
    31321 ctttctttta tataaaaggg tcgtttcctg tcaaaatgaa aaacaaaaag aggctgtgac
    31381 aaaagtcttg tcacaacccc ttattttgaa taaacggtgt tctcctgcca actcctcggt
    31441 cacaagtcac aatatccata aaacataaga agctgttttt taaaattgtt tcttgtgact
    31501 cggagctgaa cggcaggctt acaacctctt ggtaaacggt gttcaatcag ctgaccctcg
    31561 gtattagctc aaaaaacggc aaaatatgag gaactatttt gacgtttgtt tctctaatac
    31621 tcaggtcaaa acgctgattt cacaacctct ttttcggtca agttcaacaa cagtttttac
    31681 gcgtcgatct ctggcgcttt gcccaaatga gcttggatca tccagatacg tttttctgtg
    31741 gctgttttga attcgataaa gatatcttgt gttggatcgt cgccttcttc tccagaaact
    31801 tcgattcctt tttggtaaag atctgctaga taacgatagc ctgcaacaag tgtttccaaa
    31861 cgttctggaa tagtacgatc ccagcggcca atttcatcag ggatttttgt gttatctgca
    31921 aattcacgca atgtagaata aggtgaaccg tctaatgtga tcaagcgttc ggatacttca
    31981 tctaactgag cgttcaaatc atccatgaac tcatccatca ttgggtgcaa tgtaaggaaa
    32041 cctggtcctc tcatgtacca atgtgtttgg tgaacaacaa cagacatttg gcttagatct
    32101 gcaactaatt gatttaatac ttctttggtt tgttggaatt tcatctttct tgcctcctaa
    32161 cattttctta cacttaaaat aatagtagac tttcaatgaa aagtacaaca aaatcattta
    32221 cctgagaacg attttcagtt cgctttttta tccgtaaagc caatcatttt tcagaatcag
    32281 ctaattcttc tcgcagttga gcaaattgct gataagtctg tgctaaatgc ttttgtgtcg
    32341 aaacaaataa tggatagatt ttctgatatt ttttatgatc agtttcttgt actccaactt
    32401 gctctttcaa ttctatcaat tcctgtgctt cactgatact ttggatcttt ccgatgcttc
    32461 tccagcctaa aatcacagct cctaatgcgg atgcttctgt gacagtaggg aaaacaagcg
    32521 ggtaacccag tacatcagcc atcatctgac gaaaaatcgg agattgagca aacccgcctg
    32581 tagcacggat ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc cgataaaggt
    32641 tgagacagat cccttctaga atcgccttca tcatttcttt ttctgtatgt tgccgctgta
    32701 aaccgataaa actgccaaac gcatctgcgt cccaaagcgg tgctcgctca ccaagtaaat
    32761 agggatgaaa aatcagacca ttggcacccg ctggcacaaa agcgatagcc gaaagcagtg
    32821 catcatatgg attttctcct ttttctttag cagattgaac gacttcctgt aaaaatgtat
    32881 gccctgccca atcaaagatg ccagcaccat tgctagtcgc tcctcccact acccaatgtt
    32941 tctgatccag aacataacaa aacgtctcca tttctggatg gaactgaggc tgagtagtaa
    33001 taaaacgaag tgctccgctc gttcctacgg tcaaagcggc gatcgtatca ccaaaagcac
    33061 ctaaccctag attagaaagc ggcccgtctg cccctcccaa aacaaatgat atatcatttg
    33121 gcaaacctag ttctgctgct gtttttgatg gtagacctgt tacttgatag gtggaaggaa
    33181 agacttgcgg caattgctct attcgaatgt tcaagtagtc aagcacttct tctgcccatt
    33241 ggaattcatg gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg ctgatcagtt
    33301 cgccaaacaa tctataaaag atatagtctt tgataccgac aaaataagca gtttttttga
    33361 ataattcagg ttggctgttt tgcagccact tgattttgtt caatggtgtc attggatgaa
    33421 tcggcgtccc agtctgccga taaaattctt tgccaagcac ggtatatttc agtttttctg
    33481 cttcgtccgc tgctcggtta tctgcccaag tgatcattcg agataacggt gttttctctt
    33541 catccaacaa tatcaggcca tgcatcgcag aggagaagga gacaaattga atgattgtgt
    33601 ctgaaggcaa ctgtttaatt acttctttta taacggtgca gacaccttga aagatcaatt
    33661 cctgatcttg ttctgccatc ccttgtgttt cttggatcaa agggtagcga aaataagcgg
    33721 atgctgcttc ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg gttccgatat
    33781 ctaatccgat tgaaacgttc attttttcac ctcaaatttt atgtatgtac aaaaatttag
    33841 tttaagcttg cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt tattttatca
    33901 ttggttgctg tatcggatca tttttatgtt taaccgccca gcggattccg ttaggtcact
    33961 ctattattta tcctagatct cattgtgtca aatgctgtcg ttcgctttct tggtatgaat
    34021 tgattccgat tctctcgatc atcgtccaac gatttcgctg ccgctattgc aggtgtcggt
    34081 tgcccttcta ctatttgttg gcagaagcct tatgtggtgg tctttttgcc tggttcttta
    34141 ctttttcttc cgcaagaaat ttttcgacgt tcatatggat gctttcggct ttgctatttt
    34201 cgttgatgga tttattttac ttcatggtcc attctcacac gctattctgt tcttgggcaa
    34261 ttttatggat tttttggttg caggccggcg tcttccaatg gcaaagtgtg ctgttaacgt
    34321 ttatcgtagg cggtgtgtgc cttcgctatg gtcaatccta tctcggagct ggcgatactc
    34381 tgttgatgct ttcttggagt ggtggcttgt ctctagaaga gttgcttcag atcttgtttc
    34441 ttgctagtct gtttggaata tccgtttttt ctgtttactt tatctgtcat aaaaaaaagt
    34501 tggaaaagct gcctttcatt ccttttttga gcagtgcgtt gctgattgtc cttcatctta
    34561 ggtattgaaa aaaggttgtg acaaacgact tgtcacaacc tctgatatat agtgttctct
    34621 taccaaatcc ttgtgacttg gagctaggcg acaggttcac aacctctcca ctaaatggtg
    34681 ttcaatcagc tgaccctcag tattagctca aaatgctggt tttacaacct ctgatatacg
    34741 gtgttccata agtagctttt tcggcttctt atttcttgac gccccaatgt cgacgaagga
    34801 aacctgcacg tccagaacct tctcgataaa gattgtaatg gagcttgttt ttcttgtaat
    34861 aatcctgatg gtaatcttct gcaggataaa attcgcttct tggttcgatt tttgtcacga
    34921 ttggcttatc gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct gcaatatttc
    34981 gttcttcttc atcattatag tagatcactg gacgataaga atcaccgcga tcagcgaact
    35041 gtcctaatgc gtcagtcgga tcggtttgct gccaatagat ttccaccaac tgatcataag
    35101 aaataacttc tggatcatat tcgatctcta ctgcttctgt atgccctgtt gtgcctgttg
    35161 ttacttgttc ataagttgga tttggtacat gcccgccagt ataaccggat gtcacagaaa
    35221 tgatccctgg ctgctcttca aatggtttga ccatacacca aaagcatccg cctgcgaaaa
    35281 ctgctttttt tgtcatataa aatccccctt ttttctcatc ataccttgat ttccaaaagg
    35341 aggataacgt tttgcttgtg acagaaaaaa cggaaactat tatatacgtg atacggcttc
    35401 tgataaatgc caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa tcacatattc
    35461 agcagaagga agatttatgt tttcacctat tcccaataca tgcatgttac cagccaaagc
    35521 tgcttgacaa ccagcttctg aatcttcaat gaccaagcat gcatttggcg gtacattcaa
    35581 ttgctgtgct cctttgagaa aaacttctgg atcaggtttt gcttttgata cttgcgtgcc
    35641 gtcaataagg acatcaaaat aacttgtcaa attcgttttt tctaaaatga ggcgtgcatt
    35701 tttgcttgct gatcccaatc cgatcttgat gtttgttttt ttcaagtact caagaacagc
    35761 tattgcacca ggcaaaacgg atgtttcatc cattttttga atcgcttgaa gatatagatt
    35821 gtttttttgc tcagcaaagg ctgatttctc tttttctgag aatttctgtt ccatttttcc
    35881 aaatgacagc aatcgctcta gtgactcggt tctggatatt cctttcagtt gctcgttttc
    35941 tttctcagtg aatggaatgg acagctggtt agctaaaacc agccacgctt cgtaatgata
    36001 acgagctgtg tctacaagaa cgccatctaa atcgaatagt gctgctttga ttttcatcga
    36061 ttacctcctt gaaaatgaac gacttgaagt aaagatgcga tgtttttagc tgtgcgatga
    36121 agattatcag tggcttgctg taaagcttct tgtaaaggca cagctgcagg aaggatcgga
    36181 aaaacggccg aaatgccaac atctgctgct ttttcgcttc ctttaccaac acttccgcaa
    36241 atagctatca caggaacgcc ctctggtact cttctagcaa tcccaactgg cgcttttcct
    36301 tttagacttt gtccatctag acgtccttcg cctacgatta cgaggtctgc ttgctgtacc
    36361 cgtttatcga actccagtaa atccaatacg tagtcgatgc cagagactat tttccctgaa
    36421 gcaaatgcta acagtcctgc acccattcca ccaccagcac tactgcccga tgcctcgatt
    36481 acttgagggg caaatctcat ataaaaatca tgcatggctt ggtcagccac tgctaattca
    36541 ttttctttca agcctttttg tggtccgaaa acaaaagaag cgccttcttt tccgcataaa
    36601 agattagtaa catcagtaat gacagtgatt ttggctttaa tcagctcaat aggcacgttc
    36661 gttttatcaa ctgtagcaat tttacctaga ttttctccca gtgcttctac tttttgatta
    36721 tcttgatcgt aaaaagcata acctagacct tctgccatgc cgatgccgcc atcgttggta
    36781 ctacttccgc caacgccgat gatgatgtgt cgaacacctt gttgcaacaa ttgtcgtatc
    36841 agttctccta ctcctcgcgt ggataaccta agtggctgtt gttggtttag tgggacatct
    36901 ttcaatccga cgatttctgc catttcaaaa atcgcagttt gaccgtctga agcgtactgg
    36961 atttctttgt ttttgccaaa tgcattagta acgactgctg tttgccgctt caaccttaaa
    37021 ctgtctgcta atgatgaaac cgttccttct cctccatcgc ctataggtag cagatcatat
    37081 tcagcctgaa caaaaacttc ttgaaaacct gattgaatgg cttgtgctgc ctctaaggct
    37141 gtcagacttt ctttgaaaga atctggcgca atcagaatac gcattatttt cccctccgtt
    37201 ccaagatcag ttctttttcc agctggtatt ggtctccatt gacaaaaata ggtaatgttt
    37261 ctttcgtctc tttttttatt actatttgtt tttttgtcaa aacaaatagc aacctgtgat
    37321 ttttccaaat aaaaggaaaa gaaatttttt cccatgctga aggaagtctt ggagaaatag
    37381 aaagagttcc attcgttact gtaatacctg aaaaaccaaa tataactgct agccatagtg
    37441 ctcctaatga agcagcatga attccgtcat ctgatgaatg cggatctggt cctaaatcaa
    37501 tcaggcacgc ttcttggaat aaatgatacg cccattccat ttcttggata cggcaagcct
    37561 ctatggcgtg aatcgcttta ctcaacgatg agtcgtggat tgttttgttt tcatagtaat
    37621 gcaaattctt agaaacgatt ggttgagaaa aatactcagg taataagtat aacagcatga
    37681 caagatctgc ttgcttgctg acttggagtt catttacttc gctacgggca taatcaagta
    37741 aaatagactg gctgccagga cgttctttgt aagtggtcaa atcaataact ggcttactga
    37801 gatacgtgtc atcttgcgga atcagctgtt ctttgttagg cactggcaaa tataacttat
    37861 ctaaaaaatt ttgacattct ttcaaaaaaa gcggatcgcc agcttgatat ttaacagcta
    37921 aggccacatt ataatgcgcc agatagttcg tatatgcatt attgtcgata tattctgtgt
    37981 attcatctgg accaatgact ctgtgtatct ctaaatgatc atcgactttt acagctctgc
    38041 tcagccaaaa agctgctgtt tcatgaatga gcgtttttcc ctttgtttct aaaaacgatt
    38101 gatcctctgt tgcttggaca tactcttgaa cggcataagc aaggtctgca ctgatatgat
    38161 gttctgcggc agctgaagca acttcttgtc ttgttccggt tttgatattc aatgcagcaa
    38221 atttgggtgt ctcttcctga ccagtgtgtg cgctttccca tgggaaaagt gcaccttgat
    38281 agtgataatc tcttgctttt tgccgtgcgc cttctaatcg atcataacgg tacagcagca
    38341 aattctttgc tacttcagga aactgatata aaaagaaagg caggataaaa atttccgtat
    38401 cccagaaaac atgcccttta taaccttcgc cagttagtcc cttcgcccct acactaacac
    38461 ttggatcatt gcggggagtc ataatctgta aatggtaagc agcgaagtcc atcgctaact
    38521 gatcgaaaga agaatcgcct tggatcgtta tccgatgctg atgccaaaaa tctgtccaat
    38581 aagacatcga ctgctctaaa atttctgtat aactaacgct tttctgggct tgggcaatac
    38641 ttttcttaaa cgggtctgtt tgctgaagag aggtagagag cacgatgatc ttctccagcg
    38701 taaaggacgt attttttctg atcttttctg aaaaggaagc ggtgatccgg cgattttttg
    38761 cttggaatac acctgcttta ttgaatttag ctgcaatccc aatatcaatt ttactttctg
    38821 ttgtctggta ggatgcactg atcaaatcgt caccaaatac tcgcagttct ttttcaacca
    38881 actgctgtgt accaaaattg gtttgctgtc catcgatacc cgttttcaca tctacttggc
    38941 agtcttcggt caacggcttg atgaccactt tcaggactgc ctgatggaga ttattttgat
    39001 cagcaacacg acaagtaatg acttccactt tttttccttg agcagtttca atgagcgcat
    39061 agcgtttaag ctctcccatt tctaaatcta gtgcccgctc gtatgcaaga actttcatcg
    39121 tctcaagaga aaaatgttca ccgtcgattt ttatttccca tctgatgaca tctgggagat
    39181 tcactaactc ggctgattct gctcctaaag gtcggttata tacaccagct gcaaacattc
    39241 cccttacttg attccgatag tcttcctcct ggcttcctct gataccaaaa aatccatttc
    39301 caatggtcat ctgactcgca tacttattga tatactctaa atcaaactgt ttttcttcta
    39361 ctttcataag gtaataactt ctcctgtttc tgccgaacga tataaatttt ccaccagatt
    39421 ctggatgaca tatccttgcc agccatctgc aatcatctga gtctggtcac cgagcgcccg
    39481 attcacaaaa tgagccatac ttagttcatg tgggtcatta actggcgtgg tcttttgtaa
    39541 ggaaaccagc tttccatcta catcttcgaa tagttcgcct ggatacagat tagcacctgc
    39601 ctgatcgcca caaaaagcca cattcagttt gtcttctctg atattcaaag caaacgaagt
    39661 attcagttgg atgatcttgc cgttttctaa ttccagtgtg ccaaaaattg catcttctac
    39721 tgtgaatttg cttggatccc atttcccgaa tttccctgaa ttttttttcg taccaatttt
    39781 ttggaagctg tacgcccgaa cgctttttac tttaggaaat ccagtaatat acatcgctgt
    39841 atcaagcatg tgaatgccat aatcgatcaa aggcccgcct ccttgaagtt ctttgtcgat
    39901 aaacgttccc cagcctggaa caccagaccg acgaagcgca ttcgcttcta cgtaataaat
    39961 atccccgaga acatcaagat gattcttgat cattgttgct tcgtcagaaa aacgatgctg
    40021 gaatccataa gccaaaatct gcccgttttt atcggctgtc tctgccatct ttcttgcttg
    40081 atcagctgtc atagctggtg gtttctcgca catcactgaa gcattagctt cgagggcagc
    40141 caatacatgt tcgaagtgaa agcgattggg tgtacagaca ctcacgatat cgggagaaat
    40201 ctcattcagc atttgtgtaa ctgatgtata cgcatgagaa aatcctgtac gtcggcaaaa
    40261 gtcttctgct cgctggctga ctggatcaac cacagcggcc aattctaaga catctgatct
    40321 tttttgataa taagcagcat gtactttttc tgctacttgt ccagcgccta tgattgctac
    40381 tttcttcatt tatttctctc tcctttgctt atttacttat tgttattctt tctctattct
    40441 ttctctaaat catttaaatg acgcgctgtt tccagacagt ttttcaagta ttgcaatgat
    40501 tcctgataaa ttttcacttc attttctcct cgcaaacgac attcatatac catataacct
    40561 tcatactcat tttgaagtag cgtttgaaaa tggcgagtaa aatcaattgc gccagatcct
    40621 ggttggtagc gatgattatc tgctaaatgg atatgaccca catactcttt ttgcgtagtc
    40681 aatgcttttg aaatatcatc ttcttcaata ttcatatgat aaaaatcagc gatgatctgc
    40741 acatgtttca attgattaga gtcaatgtaa tgacgcgcat ccgctaacaa attgatcata
    40801 tggtcttggt atcggttcaa aggctccaaa taaataaccg tacctgtttc ttcggctact
    40861 ttatctaaat aacgaagtga ttcgctgact gctttatagt ctccttcttt gcttcggggt
    40921 gaaaccatcg gcggtaatcg ataagtgaac attccccaag ctgctgggat aacgattcct
    40981 ttgcctccaa cctcgcttag tgcacgcaaa atctcagcaa tttgacgtac accattaaga
    41041 cgccgttctt cgataaagtc accgatccac ccatcgtagc cgttacaagc tgtcactact
    41101 gggatccctg tttctttgat tgcctgtttg actgtgtcga tattttctat taacaactta
    41161 ccgtcgattt cgtattcttc aaatccacag tctttgataa atctaaattt ttctaaaatg
    41221 tctcttggga aaaatgcttg atcttgcgta ccgaatttca ttgttctcct cctcggactt
    41281 gaacgcccat tttgatactt tcttctgggt gctggtctac ataacgcatg taagcttctg
    41341 cgctttctgc aaatggcaca actggatcaa tgatttcttc acaatccaag taaccgttca
    41401 tcaataattc ccaacatgtg tcctcgattc gtttacggtt ccatcttggg taatctgggt
    41461 ttggttcact agatgctcga gcaaagacga tttttgcatt attgaaatgt gcttcgcgac
    41521 caagattaaa cccagctgga aaaggtttag caaaggcaac ataagaaatg atcccgccat
    41581 agccgatccc tattaaagaa gcttgtaatg cggcagcact gccactcgtt tcaataactg
    41641 aatctactcc acgtttatct gtcaattcct ttagacgaaa accgacatct gctttcatag
    41701 gatctagcgt gtaatcggca ccgtgttttt ctgctaattc tctacgctgc gctatgggat
    41761 cgatcccaac gatggtagta gcacctgctt ttttagctaa ttgaatcgca atttgcccga
    41821 tagcgcctaa accgaagatt gctacagcat cacctgctcg aacatgtgct tcccggatac
    41881 cacctaaagc gaattgagca ggatcgtaac atactgcatt tttccattga tccaaccgat
    41941 caagtttacg tagtttataa ttatcaacac cgtttgtaat cagcgtttca cgaatgggtc
    42001 cataagtgca gactaactct cctttttgat actctgtcac caaactgccc gtttcttcga
    42061 tcgtaccgac aatcatattt cctaattgaa attcgccaaa taccacaccg cgttggcttc
    42121 cttcttctct tggcaagaat aggcgccatt cttctgaaaa ttcttcatcg ataaatggac
    42181 ttaatcctct aaagtcgaca atttctgttc ctggttttgg agtagcgaaa attactcgga
    42241 tacgtacttc gttcttttcg atctcacggt cttcgtaatc tttgaatccg gctattcttg
    42301 gttctaatgc aactaatttt ttcatctttt ctttcctctt tcttttcttt ttatcctttt
    42361 acgccgcctt cgactaaatc acctttaata aatcgttcag ataacgcata cataatgatg
    42421 actggtaaag cggtcaccaa tgaagcggcc atcattcgtc cccaaatgta gtctggtgta
    42481 ctgaataatg tgttcaaacc gattggtaaa gtaaattttt cggaggtcga caggaaaatc
    42541 gaagcaaata aataatcatt ccacgaaacc ataaagcaat aaacgaagac agaaatgatt
    42601 ccagaaatag ccaatggtat aatgatccga ataatgatct ggatccggct aagaccatcg
    42661 atcattgctg cttcttcaat atcagtcgga atcgtgtcaa aataactttt tagcatgaat
    42721 atcgcagtag gaagtgtttg aacgaccatc gtgataatca gtgctgtatt ggtatcatac
    42781 aaacctagac cggaaatgat tttaaataat ggaacaacga tcaaaatacc ggaaaacata
    42841 taaacggtgt aaaagctagc attgattttc gagcgagctt tgaagcgtag ttttgacaaa
    42901 gcgtatgccc cgctgatccc aatcactact gcagttacgg aggctatcaa ggagatcact
    42961 aaactatttt tgaaatacat gatgaatgga aaaatctcag cattgaaaat atcctgataa
    43021 tgttcaaaag tccattcttt cggaaaaata gtttgtgtcg ttgcaattgc ttcttgtgaa
    43081 tccttgaatg atgtcatcag catgatcaaa aatggaaaca aattgacagc taatagcaac
    43141 aaaatcgtcg cgtaaaataa gattttcctg ctctttttat ttttcatttc aagtccacct
    43201 tctttcgtga gagcaagacg accgctgcaa taatgatgaa caatagaatc gatatagctg
    43261 ctgcttttcc aagatcattg aacgcaaagg ctgtctgata caaataaacg cctaagatat
    43321 tgactttatt cgtcagtaga tagacatctg taaacatata gaacatccag atagatcgta
    43381 aaacaatcac agttgctagt actggtttga ttgccggcag tgtcacgatc ttgaacttct
    43441 gccaagcatt tgcaccgtcc atttcagctg cttcataaag cgttttgtcg actgtttgca
    43501 aaatagccaa aaatgaaata aacgcatacg gatagtatct ccagatagca aacaaaacga
    43561 ccataaagaa gctagcaact ggctggtcga accacagcgg tgcttcgttg aaaagctgca
    43621 acctatctac taacagatca ttgacgattc cataactatt attgaacata tatttccaag
    43681 caaaaatcaa agaaatagat ggcgtaacat aacttaataa aatcagtgaa cgcaccgttt
    43741 tcctaaatct gaacttgcgg ttaagcaaaa tagctacggc taatcctaaa gctgtactgc
    43801 ctgctacaac taagaatgtg taagcaactg ttaaacctaa agaacgataa aattcactat
    43861 cacttaaaat ttcaagataa ttgcttaatc cgataaaaac ggcgtctgag ttaggattca
    43921 gcggcatatc gaaaaaactg atctgaatat tggaaagcat tggaatcagc actaaaacag
    43981 ctaataaaag catgcttggt gctaaaagtc ccatggctaa ttttaagtca gaatgtttcc
    44041 ttggacgatt cattgaaacc tccccctgat aatctgccaa tagctatcta cttttttcga
    44101 acaccattgg cagaacttct tgttatttcg tatttttttg tgcgtcagct aaagcttgat
    44161 cgacatcttc gtttccgaca gttacttggt tcactgcttt tccgatcaca cctgagcttg
    44221 tgatatctcc cattttcgtg aaattctttt ccccgactag tccaaagact tgtacttcat
    44281 caaaagcact agcaatctca gatggcagct cgccaaaaga cttgatgact tcattttctt
    44341 tgtaaccatc cagttcgact acttgtttat tcactggttg agcaccacca ggagacatca
    44401 agacccactt ttccatgttt ttcggttgag ataagaaagc tgtgaatgct tcagcagcct
    44461 ctttttgttt ctcgtctaga ccagaagaaa tcgtcaatcc agatactgtg ccatagacag
    44521 cttgatcttt ttgtgttggg atagcaaaac cgatattttc tgagttcccc gcttcataaa
    44581 cagaaggcaa aatgtaagtt gaatagattg ccattggtgc tgttccattc atgaaagcat
    44641 ctttgatttc tgtcacatca ttagagcctg gcatcgtgta ttgggataag ttttgataaa
    44701 acgacaatgc ttctctcatc ttttccgtat cgatcgttac ctcgccttca tcatccaaaa
    44761 catttgctcc atttgacaaa gcaaattgag agaacgcttg ctcactcatt gttccttcag
    44821 cagtaggcat agcaattcca tattgtttat tctctttatc tgtgaaatgt tgagcaattt
    44881 ttaaaatatc atcccaattt tctggttctg aaaaaccagc ttctgataat ttttctttgt
    44941 cataccaaat accttgaacc cagccgctaa ttggtgcagc aatatagctt tttccatctt
    45001 ctgaacgaac aaggtttttg gctccgtcat aataattatc ttctccagct tcctcgataa
    45061 cgttttggac tgccgtctga tcaatcagtt catctttatc catcacttta gcaaaatcct
    45121 gactgacttc cattacttct ggtaatttac cggaacgagc taacgtaacg atttttgtat
    45181 tgaacgctga ttcttctacc ggcacttgct tgattttgat gtctggattt tctttttcaa
    45241 aatcagcaac cagttcattg atcacactta atcgttcctg ttcgacagaa gagtgcatga
    45301 attgaatcgt tgtctgttgt gattcgttag agctttgact ttcaccacaa gcagtaagaa
    45361 gaaatccagt agctagcaga caggtagtaa caataatttt tttcattttt ttccacctct
    45421 tattttatta ttttcagcca catatattca tacggctgga atatcaactt tcgttcttga
    45481 ctgcaatgga taatttgtcc agaaaacagg tctaggtaat ctccttttgg taaaagataa
    45541 cctgctgatt gattggaaaa attatggata actaagactt tctcttcctt cgcttcgcga
    45601 ataaaactga taaaagaatc tgctgagtcc agtaagtaaa tcaaactatt cggatggaag
    45661 gctttttctt tttttcgaat agatagcatc tgggtcaatt caccatatac tgctgttctt
    45721 aatggatctg tctgcaactc tttctcaata tctgctaaca aaaatttttg ccgattgatt
    45781 tttcgattct ctcctgtttt ttctacgcct ttgtaatcat ttcgacttcc cagcacactt
    45841 tgaatataaa ttgccggcac gcctggtaac gttaccaaaa atgaatgagc agctaaaaag
    45901 cgtttgcttc tccattccgt cgtatctgtt ggagaactta acgcatctag atacgtagcg
    45961 tttatctcat atggactggt cgttccatct gggtttttct tgtagtttac tcgggcaccc
    46021 tctttcttca gctgttccac taattcaagg atcgtttttt ccggcagaat acctcgtacc
    46081 ggattcaatc cgataccgtc atgggaggct aaaaaattaa aaaaagttgt ttttttcgat
    46141 gcgaaatcga tggtttttaa ccattctttc aacttacttg tattacccga acgaatcgct
    46201 tgaagggtca aaggtggtag cgaaaactga tagaccatct gtgcttcatt ctcgccattc
    46261 ccaaaataac tgatattatc tttgtgtggc acatttgtct cagtgatcaa taccgttcct
    46321 ggagctgctt catcagcgat tgcacggaat aattggatga ttttatgcgt ttctggcagg
    46381 tgtatacaag aagttcctag ttctttccat aaaaatccca cagcgtccaa gcgaataaat
    46441 gaagcgcctt tttctaagta aaacaaaaga atatcgatca ttttcaataa aacttctgga
    46501 tttttaaaat tcaagtctac ttgatcttcg ctaaaagtcg tccatacgtg tttttctttc
    46561 ccgtttttgt caatgaacgt tgtaagtaac gggctggtcc ttggtctagt cacgctgctt
    46621 gtatctgtat ccagtggcaa atcaataaaa aaatctttgt acgtatcatt caagtttaaa
    46681 tattcctgaa accaagtact ttcggcagac atatgattgc agacaaagtc gaacattaac
    46741 cgtgtttcgc ttctcatttc ttctatatct tcccatgtgc ccaaacggtc gttgattgcc
    46801 tgataattta caacggagaa accatcatca gatgtatatg ggaaaaatgg caagaaatgt
    46861 acaactctaa atgtatctgc caaatacttt tgataaaatt tcttaaatgt acgcaaagtt
    46921 ggttgctgct cttcaaaaaa ttgatcccca taagtaatca agaaaatatc ttcttcgtcc
    46981 caatgcagtt tgcctgcctg gcctttcttc tgctgataaa cactgacttt ttgttcaatc
    47041 atagaggcgg ttttctcaga caaatctgag tcgcgataaa tcgcttgtaa aagttttgta
    47101 tacatcggat tcccctttct tttttgggag cgttcccaac gatttgatca tattatggaa
    47161 aacgcttact gtcaatagca tttttttaaa taattttgat atacacaaaa atacaaataa
    47221 gaaagcttat gtatcaataa ttaatagctt cttaaaaaaa tatggtctct catgatcatg
    47281 caagctattc ctaaattttc aaaatcatag acaaaaaaga atgtctattg tactatggaa
    47341 ttattctaaa acgctcccaa aaaggaggtg catataaaat tgaaacctac tatttatgac
    47401 attgcgaaaa aagctaatgt ctcaaaatca actgtctcca gagtattaaa taaccagcca
    47461 aatatctctg ataaagcaaa agcaagtgta cttcaagcaa tcaaagaatt gaattatgaa
    47521 ccgagcaaaa ttgcaagagg actgtcagga aatggttttg acgcgattct agcattatct
    47581 catcgtactt ctcatacgac ctatggcaat cctttttttt cagatgttat tcaatccatt
    47641 tctgccgttt ctgaacaaaa taacttcgac ttgattctac aaacggcaaa aacaccagaa
    47701 gaagagctag aaaaatgcgc gaaaaagatc caagaaaaaa tgatccgagg aattattatt
    47761 ttaagctcta cgatggatga aacacttctt tttgaattgg atcaatacaa tattcctatt
    47821 gtggtaatcg gaaaagtcgg aaacgactac acgaacatct actcagtgga cacggataat
    47881 ttccaggata gttacgattt ggtggaaaca ctgatcaaga atggacaccg tcatatcggc
    47941 tgtctccatg ctccgacaga agtttatgta tccaatgatc gtctcaatgg ttaccgtcaa
    48001 tgcttatttg atcaccacct agatatccgt aatgaatgga ttatagacgg cggctttcgc
    48061 ttagaagata gcatggcagc aatgaatgat ttaatgaagc tacgagaaag accaactgcg
    48121 attttttcta ccgatgcatt aaaatcattg agtatttaca aagtggcaga acaatctgga
    48181 aagcagatac ctgatgatct ttcgatcgca ggattcagtg atcccttatt gtcctcccta
    48241 ttttcgccac agttgactcg gatagacatt ccgacaaatc agttaggaat caaagccaca
    48301 gaacttttat tccaactaat ccaccaccaa taccctgaag aaaaaagaat cattctttca
    48361 accgagatta ctctcacaga ttcgatccaa caacaagaaa tgtagaacag aattataaaa
    48421 gaacagaaac actgaggata agtcagttac tctgttcttt tttcaatcac tcatccctcg
    48481 ttaccccctc ccggtatttt agcgaatttt tcttattttc catctgtttt agatagctgt
    48541 ggataactat aatgtttgtg ttaaactatt ttttccacag ggaagaaaaa actattttta
    48601 accacgttgt gtataagttt ttatagttcg tttttttaaa cacatttacc cttatttcaa
    48661 tccatgttat ttggggatac ttatctctaa aacataaata gaataacaga catgtctact
    48721 ggttttgttt tattcgagga attattcaat aatagctagc aaaatattaa aaataaccgc
    48781 tctatcttcc catcaattta ttttgcattc aaaaaatgat ctatctttac ttttgttgat
    48841 tgacttctct tggaagatga tcgttccgat accttaattg gatacgaacc gatgttgtta
    48901 agatcctttc ccacttttct tctagttaga caaattattt tagacaaacc aaaaaagagg
    48961 ttgtgacaat aatttgtcac aacctctttt ttaaaatatc tattttgttt gattgttcat
    49021 tgcgtcttct gcagccattt gcgcttcaat atctgaaata ctgtagacat tttcgcttgc
    49081 tacaccgact tcttttggtt ccatgtcacg ataacgttgc ataccagtac cagctgggat
    49141 gatcttacct ataataacat tttctttcaa accaagaaga ggatctttct taccgcggat
    49201 cgcagcatcc gtcaagacac gagttgtttc ttggaatgat gcagcagata agaaactatt
    49261 tgtttctaat gatgcttttg tgatacctag taagacaggt cgagaagttg caggaacgcc
    49321 tcctgagact agcgtattgt agttttgatc tttaaagtct gcgatgtcta ataatgtacc
    49381 tggtaagata tctgtatcac ctggatccat tacacgaact ttacgcagca tttgacgaac
    49441 cattacttcg atatgcttgt cgccgatttc taccccttgc atacggtaaa cacgttgtac
    49501 ttcacgaagc aagtagtttt caacagataa tacatcgcga acttgcaaca attgttttgg
    49561 atcgattgat ccttctgtca atggtgcacc acggtggatc atatcgcctt ctgctacttt
    49621 catacgtgct gtataaggaa cagtatacgt acgtgtatct gtttttcctt tgattgttac
    49681 ttctttggta cgtgttgcag gatcttctga gatatcgatg acatcccctg ttacttctgt
    49741 gatcactgct tgccctttcg gattacgtgc ttcaaagatt tcttggacac gaggaagacc
    49801 ttgagtgata tcgtctccgg caaccccacc tgtatggaat gtacgcatcg tcaactgagt
    49861 accaggttca ccgattgatt gagcggcgat cgtaccaact gcttctccga cttcaacgtc
    49921 agagccagtt gcaaggttgc gtccgtaaca atgtttgcag acaccatgtt ttgtattaca
    49981 tgtgaagaca gaacggattg tcactgtttc gacacctgca tcaacgattt gttttgcgat
    50041 gtcttcggaa atcaattggt ttcctgcaat gatcaattca tttgtttcag gatgacgtac
    50101 ttctttacgg gtgtaacgtc ccactaaacg atcttctaat gattcgatga tttcatttcc
    50161 ctcgcggatg gcttggattt caagacctcg gtcagtaccg caatcttctt cacggatgat
    50221 tacatcttgg gccacgtcaa ccagacgacg agtcaagtaa cctgaatcgg cagtcttcaa
    50281 ggctgtatcg gtcatccctt tacgagcccc gtgagttgag ataaacattt ccaagacgga
    50341 tagtccttca cggaagttcg aaatgattgg caattccatg attcgaccat taggagcggc
    50401 catcaaacca cgcattccgg caagctgtgt aaagttggaa atgttaccac gagctccaga
    50461 atcagacatc atgaagattg gatttttcgc ttccaaacct tccatcagtt tttgttggat
    50521 gctgtctttt gcagcattcc aaacagcaat gacacgttca taacgttcgt catctgtgat
    50581 cagaccacga cggaattgtt ttgtaatagt ttcaacttgt ttatgggcat tttcaatgat
    50641 ttcttgtttt tcattcagta cactgatgtc agcgatccct actgtgatac cggcatgtgt
    50701 cgaatgtttg taccctaagt ctttcatacg gtcaagcatc ttagaagttt ctgttacttt
    50761 gaatcgtttg aagacttctg cgatgatgtt tcctaagttt ttcttcttga acggtaatac
    50821 taattcttgc tctttgatat gtgcaggaat atcagtacca gcttcaacaa agtatttgtc
    50881 cggtgtttgg acggtcaagt tgaagtctgt tggttcattc agataaggga attcaggagg
    50941 catgatctcg ttgaagatga tcttaccaac tgttgtgatc atcgtacgtt ctttttgcca
    51001 ttcagtaaat ggtttttcac ctaatgagtt agggttcaca ccgatacgtg aatgtaaatg
    51061 aacatatccg ttgcgccatg cgataacggc ttcgttttga tctctgaaga ccattccttc
    51121 gccttcgcgt ccttcttctt ccattgtcaa gtagtagtta cctagaacca tatcttgaga
    51181 aggagtaaca actggtttac catctttagg gttcaagatg ttttgagcag ctaacatcaa
    51241 catacgtgct tctgcttgtg cttcttcatt caatggaacg tggacagcca tttggtctcc
    51301 atcgaaatcg gcattataag cttcacatac aagtggatgc aaacggattg cgcgtccttg
    51361 tactaaaact ggttcgaatg cttggatacc aagtcggtga agcgtaggtg cccggttcag
    51421 caatactggg tgttccttga ttacgtcttc taaaacatcc catacttcgt cttcttgacg
    51481 ttcgatttta cgtttcgcat ttttgatgtt tgaagctagt tcgcgttgaa caagctcacg
    51541 catcacgaat ggtttgaata attcaatggc catttctttt ggaagtccac attggtacat
    51601 cttcaagaaa ggtccaacaa cgataacgga acgacctgag tagtcgacac gtttacctag
    51661 caagttttga cggaaacgac cttgtttccc tttcaacata tgagaaagag atttcaatgg
    51721 gcggttacct ggtccagtaa ctggacgtcc gcgacgaccg ttatcgatca atgcatctac
    51781 tgcttcttgc agcatacgtt tttcattttg aacgatgatt ccaggtgcat tcaagtctaa
    51841 caaacgtttc aaacggttat tacggttgat tacacgacgg taaagatcat tcaagtcact
    51901 tgttgcaaaa cgtccacctt ctaattgaac cattgggcgt aaatctggtg gaataacagg
    51961 gataacgtcc ataaccatcc agcttggttg atttcctgaa gcgcggaatg cttctaaaat
    52021 atccaaacgg cggattgcac gtgtacgttt ttgtccttgt gcagatttca attcttcttt
    52081 caattcggct gcttctgcat ctagatcaac attatcaagt aattgtttaa tcgcttctgc
    52141 acccatagca gcttggaatt cttgtccata ttgttcacgt ttttcgcgat attcgcgttc
    52201 tgtcaacaat tgttttttct ctaaattcgt atttcctggt tcgatgacta catatgaagc
    52261 aaaataaatg atttcttcca aagcgcgtgg gctcatgtct aatacaagac ccatacgtga
    52321 aggaatccct ttaaagtacc agatatgtga aacaggagct gctaattcaa tatgtcccat
    52381 gcgttcacgg cgaactttcg aacgagtaac ttccactccg catcgatcac aaacgattcc
    52441 tttataacgg atacgtttgt attttccgca ggcacattcc cagtcttttg taggaccaaa
    52501 aatccgctca cagaacaacc cttcgcgttc aggttttaag gtacgatagt taatcgtctc
    52561 aggttttttt acttcaccgt aagaccagct tctgattttt tcgggagaag ccaaacctat
    52621 ttgcatactt tcgaatttat ttacatcgat caaaaggggt tccctccatt tcatttaatg
    52681 gcaaaccgca agacggctga tcttcgaccg ccttgcagct catagaccgg attagtctaa
    52741 attatcttct gcggtttcaa agttttggat gacatcgtct ttttcatctt ccacttgttc
    52801 agcagctttc ttttctaatt ctttggcagt ttgctgttcg gcaaattttg tcaaagcatc
    52861 aacagtgatc aaatcgtcgt cttcatcgtc catgtcgcga agttcgatct ctgtttcttc
    52921 gatatccaag acacgcatgt ccagacctag tgattgcaat tctttcacca atacgcggaa
    52981 tgattccggt acacctggtt ttggaattgg ttcacccttg acgattgctt cgtatgtttt
    53041 cacacgtccg actacgtcat ctgatttgta tgtcaagatt tcttgtaaag tataagccgc
    53101 accgtaagct tccagtgccc atacttccat ttcaccaaaa cgttgtccac caaattgagc
    53161 tttacctccc aatggttgtt gtgtaaccaa tgagtaaggt ccgattgaac gtgcatgcaa
    53221 tttgtcatcg accatgtgag caagtttgat catgtacatc acaccgacag acacacgtcc
    53281 atcaaatggt tcacctgtac gtccgtcgta cagaacagtt ttcgcatcgc tggccatacc
    53341 ggcttcacga actgtttccc atacgtcttc atcacttgca ccatcaaata ctggcgttgc
    53401 tacgtggata cctaactgac gtgcagccat acccaagtgt aattccaata cttgcccgat
    53461 gttcatacgt gaaggcaccc ctaaaggatt cagcatgata tcgattggtg ttccatcagg
    53521 taggaatggc atatcttctt ccggcataat acgggataca acccctttat ttccgtgacg
    53581 accggccatt ttatcccctt catggatttt acgtttttga acgatataaa cacgaactaa
    53641 catgtttacg cctggtgaca attcatctcc agcttcacga gtaaagattt tcacatcgtg
    53701 aacgataccg ccgccgccat gtggtacacg taatgatgta tcgcggactt cacgagcttt
    53761 ttcgccaaag atcgcatgca atagacgttc ttctgcagat aattctgtta ccccttttgg
    53821 cgtgactttc cctacaagca aatcgccatc ttggacttct gcaccaatac ggatgatacc
    53881 catttcgtct aaatctttta atgcgtcttc cccgacatta gggatttcgc gtgtgatttc
    53941 ttcaggtcct aattttgtat cgcgggcttc tgattcatat tcttcaatat ggatagaagt
    54001 gtatacgtca tcttttacca aacgacggct catgatgatc gcatcttcat agttgtaccc
    54061 ttcccaagtc atgaaaccaa ctaaaacgtt ttggcctaga gccatttcgc cttgttccat
    54121 agatggtccg tctgccagag tatccccttt ttcgactttc tcacccaaat gaacgattgg
    54181 acgttggttg tagcttgttc cggagtttga acgacggaat tttgttacat cgtatttatc
    54241 taatgcaccg ttgtcgcggc gtacgcggat ttcagaagca tcaacgtatt caacgacacc
    54301 gtcatgttta cataacaaag cagctcctga gtcatgcgct gatttgtatt ccataccagt
    54361 accaacccat ggtgcttgag gattgatcaa cggcactgct tgacgctgca tgttggcacc
    54421 catcaaggca cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc
    54481 aactacttgt ttaggtgata cgtccatgta gtctacttta tcaatagata cttctaagtt
    54541 ttcactttga gcacgagcca taacaacgtc ttgagcaaat gttccatctt cattcaatgg
    54601 gctgtttgct tgggctacga tgtaatggtc ttcgatatca gctgtcaagt agtcgatttg
    54661 gtcagtaaca cgacctgttt cacggtctac acgacgataa ggtgtttcga taaatccgaa
    54721 tttatttact ttcgcataac tggacaaact attgatcaac ccgatgtttg ggccttcagg
    54781 agtttcgatc ggacacatac ggccatagtg ggagtagtga acgtcacgaa cttcataacc
    54841 ggcgcggtca cgagtcaatc cgccaggtcc taaggctgaa agacgacgtt tgtgtgtcaa
    54901 ttcgccaaga gggtttgttt gatccatgaa ctgtgacaac tgagaagaac caaagaattc
    54961 tttgatactt gccacaactg gacggatatt gatcaattgt tgaggtgtca atgtttcagt
    55021 atcttggatc gacattcttt cacgaaccac acgttccata cgtgctagcc cgatacggaa
    55081 ttggttttgt aaaagttcac cgactgaacg gatacgacga tttcctaagt ggtcgatatc
    55141 atcgacattg ccgatacctt ccatcaagtt caagaaatag ctcattgaag caatgatgtc
    55201 ggctggacga accgttttta cagctgcttc tggatagccg tttccgatca cgtttacttc
    55261 acgttcaggg tctcttggtg aaaatacttt gatgacttgg acagtcattg gatctgtgac
    55321 cacaccgtct tctgatggat agtaagtcac tgaatttagg ccattatcaa tgaaaggagc
    55381 tagtgtttcc atgacttggt gagtcagaac tgttcctttt tcaacgatga tctcgcctgt
    55441 ttctggatca actaatgttt cagctaatgt cagattcaat agacgtgttt tcaaatctaa
    55501 ttttttgttt actttgtaac gaccaacgtt tgctaagtcg taacgttttg gatcgaagaa
    55561 acgagcattc agcaagttac gtgagctgtc tgctgttttt ggttcgcctg gacgcaaacg
    55621 ttcgtaaacg tctttcaaac cttcttctgt tcttgagtcg cttgcgtttt tatgcaagtc
    55681 tttttcgact gtattgcgta atgtttcgct gtcgccgaag atttcaaaga tcgtatcatc
    55741 ggaaccaaat cctaacgcac gaactaatac ggttaaagga atcttacgtg tacggtcgat
    55801 acgtacataa gagatgtctt ttgcatcagt ttccatttct agccaagctc cacggttagg
    55861 gataacagta gaaccgaatc cttcttttcc gtttttgtcg acttttccat ggaaatagac
    55921 acctggtgaa cggactaact gagaaacgat tactcgctct gccccgttga tgatgaatgt
    55981 tccttgttct gtcattaatg ggaaatcacc gaagaatact tcttgtgctt tgatttcgcc
    56041 agtctcgcgg tttgtcaaac gcaatgttac atgtaatggt gcagagtagt ttgcatcatg
    56101 cgcacgagct tctgctactg tatactttgg ttctttcaat tcataatcta caaattccaa
    56161 agatagattg ccattgaagt catcgattgg caaaatgtct tcaaacattt ctctaagtcc
    56221 ctcatctaag aaccattggt aagagtctgt ttgaatttcg atcaaatttg gtaattccaa
    56281 cacttcactg attcttgcga aacttctacg ttcgcgatgt tttccgtatt ttactacgtg
    56341 tccagccaag ctcttcaccc ctctaaaatg tcattcaaaa agactacccg atcaattgtt
    56401 acaataatat ttcaaatatt atttttaggt aacaacagac attttttgcg gcttttaggc
    56461 aaaaaaaaac caaaaataga acattctctt gaaaccttac ttcgtgagct tctacttttg
    56521 tttccttata ttaaagccga aacggacaat atttcgtttc tgccttttct tcatcagata
    56581 gtttttgcaa cttcatatac tacacttatt ttctataaaa gtcaacactt cctggcgttt
    56641 cttctgcttt ttcgcaacat tttcttaatg ttttcaattt tatgttttca attatctgac
    56701 aattcttaat tgacagacct ttttatctcg gttatacttt agaaaattca ttttgtggag
    56761 gaacttctat gcgaaccaac atcaaccaaa tcgcaccaac acaactgaat aacttttact
    56821 ttagctactt tagataggtt tgtattcatc atgatggata caaacgttaa acgacagttt
    56881 gtatctatga tggctaaaga actttgtatt gcagcaaaaa gccacgtaga caaaatgcta
    56941 agtggctgag cagtgaaaat acaaagtaaa agtatcaagc attctacttt ttcaatttat
    57001 tttccgactt ttcaatccat ttggacattt tgtctgaatg gattttttgt ttcccaaaat
    57061 taaggaggaa aaagaaatga aaaaaaatat aatcatcgga ttaggcgctg ccctgctact
    57121 agctttagga ggttgcgcac aaaaagacaa ttccgcagag gcatcagatg gacaaaaaac
    57181 aattggcgta ttgcaacttg tacaacataa ctcgttagat gctgcctata aaggattcaa
    57241 agaaggatta gcagaagaag ggtataaaga aggcgataat ctaacaatcg attatcaaaa
    57301 tgcccaaaac aatcaagaca acctgaaaag tatgagtgag aaactcgtca aagaagatcc
    57361 tgatttgcta cttggaatcg ccactccagc agcacaatct ttattaaatg aaacaaccac
    57421 tatcccgatg actgtcacag cggtcacaga cttggaacaa gcccatttag tcacatccaa
    57481 tgaaaaacct ggcggcaatg tgactggcac gacagatatg gtgccaatcg aaaaacaaat
    57541 cggcttactg ttaaatatcg tgccagacgc caaaacaatc ggcatcatgt ataacaacgg
    57601 tgaagcaaac tctaagatcc aagctgattt ggcagaaaaa gaattgaaaa aagcgggcgt
    57661 caaagtcaaa gtactgacag caaattccac aaatgatgtc caacaagtga cgaaaagtct
    57721 agctaaagat gtagatggaa tctatattcc tactgataac acgttcgcaa gtgcggcaag
    57781 tgttgtcggt gaagtcgcaa aagaaacaaa aacacctgtc gttgctggcg cagttgatca
    57841 agtcaaagac ggcggtctag caacagtagg aatcgactac gaaagcttgg gcaaacaaac
    57901 agggatcatg gcagcaaaaa tcttagacgg caagaatcca agtgaacttc ctgtcgaaac
    57961 agcgaatgat ttggaactgt atgtcaataa agacatggcc aaagcattag gcatcaatcc
    58021 agacagcatc aaagaagctg aataaaacac aggaggattc tcatgacaaa tttgctctct
    58081 cttttcttat catctgcatc gcaaggggtc ttatgggccc tacttgcgat tggtgtatac
    58141 gtcactttcc gtatcttgga cattgccgac ttgactgctg aaggaagctt tcctttaggt
    58201 gcagggatcg cggcagtaag tattacaaat ggctatcatc cattgacagc ttgtcttcta
    58261 ggctttttag ggggtgcggc agcagggctt gtttccggac tgcttcacac aaaattgaaa
    58321 attcccgccc ttcttgcagg gatcatcacc atgactggtt tatattctgt cacatcccgt
    58381 gtgatgggtg cgccgaacat ctctttattg ggtcagccaa cgatctttca ttgggtcgag
    58441 tcattcggca taacaaaaga caacgctgta ctgatcgtcg gtctgctttt tgctttgatc
    58501 gttgtatgtt tacttgtttt gttcttacgt acagaaacag gacttgctat tcgtgcaact
    58561 ggcgataatc tggcaatgag cgaagcaaac gggatcaaca cagataatat gaagatcatc
    58621 ggttatatga tttctaatgg atgcattgct ctttctggct ccttacttgc gcaaaacaac
    58681 ggctttgctg atttaaattc tggtattgga acgatcgtaa ttggacttgc ttctattatc
    58741 atcgcagaag ttttgttacg taaccagcca ctatttctcc gtctcttgac tgtcgtttta
    58801 ggtgcggtca tttatcgttt tattttagcg ttagtcttcg aactgaatgt tgaaccaagt
    58861 gattcgaaac ttgcttctgc tttcgtgcta gtgatctgtc tttctttccc gcagatccag
    58921 caaaaattcc atttacctca aaaaaagaaa ggcggtagtg tcaaatgaat gacgtcttaa
    58981 cattggaaaa tctccatcat acctttgaaa aaggaacgat caacgaaaat catgtcctga
    59041 aaggcattaa tctttcctta gatcccggcg acttcgtgac gatcatcggt ggaaatgggg
    59101 ctggtaaatc tactttgctg aacagcatcg ccggtacatt ttctgtcgat cagggtcaaa
    59161 ttttattgaa tggaaaaaat atcacgaaaa aatctgttgt cgaacgttcg aaatccatca
    59221 gtcgcgtatt ccaagatcct aaactaggga cagccgttcg tttaacggta gaagaaaatc
    59281 ttgctcttgc tatgaaacga ggaaaaaaac gcggcttctt ccgtggtgtc aaaccacaag
    59341 accgaacatt tttcaaagac cagctggttc ggctaaattt ggggttggaa aatcgtttat
    59401 cctcagaaat cggtttgctg tctggaggac aacgtcaagc tattacgtta ttgatggcca
    59461 cattacagcg tccagaactg atcttattag atgaacacac tgcagcgctt gaccctgcta
    59521 cttccaaaac ggtgatggaa ttgacagaaa agctgatcac tgagcagaat ctcactgctt
    59581 ttatggtcac tcatgacatg gaagacgcga tccgctatgg gagtcgactg atcatgctgc
    59641 atcaaggaag gatcgtcgta gatatccagc aagaggaaaa acagcagctc acagtgcccc
    59701 aattattagc gttgttcaaa caaaacagcg gcacggcatt aaaagacgat caagtacttt
    59761 tatcttcata atcagaaaga ggatgggaca aaaaatgaac gcccaccctc ttcttttttc
    59821 tctttccttc tttcgttttt gctttatgta tcaaccgttg tttcttcgaa aactattttg
    59881 ttctctcctt cttcctgata gaatggatgg gaaaggagct tgatgccatg acaacgaaag
    59941 acaaggtact tcaattattg aaaaagacac cagattttct ttccggagaa aagttggcac
    60001 agcaactgga agtttcccgg acaagtattt ggaaagccat caaagaattg gaaaaggcag
    60061 gctatcgttt tgagcacggg cctacagggt atcgttacct gccctctgac gtactagatg
    60121 caaaagaaat ccagcaagag ctacggtcgt ttattcctga tttgaaagta caaacgatgt
    60181 tgacttctga atctacgatg aaagatgcca aactggcagc agctcaagga gattctgttt
    60241 cgaagttatt tgttgctgat acacaagaac aagctcgtgg acgttttgga cggccttttt
    60301 tcgctgaacc tggacgagga atctacatga gtctcttgct ccatccagac aaacggtttg
    60361 atgaattgcc tcaatatacg atcatcgcag ccagtgcctg tgtgaaagcc attgaatctg
    60421 taaccggtcg ttctgcttcg atcaaatggg tcaatgatat ctacatggat ggaaaaaaag
    60481 tctgtgggat tttatctgaa gcagtcagtg atatggaaag cggcaggatc agtcatatca
    60541 tcattgggat cgggcttaat ttttctgttc ctcaaaatca ttttccagct gatctccaag
    60601 aaaaagccat ctctgtcttt cccgacggac aagctagtgt cacaaggaat cagctaatca
    60661 gcaaaatctg gcaagaattg ttcacttatc tttctcaccc agaaaaagcg ttggacttct
    60721 ataaagaaaa atcattcgta ttgggaaaaa ccgtgtcgtt caatcaaaaa ggaacgactt
    60781 atgtcggtct tgcaaaagaa atcggtgatc atggcgaact gatcgtccaa acaaatgaac
    60841 agaagatgag tttgtcttct ggcgaaatca gtctcacatc tatccgtacg caataattat
    60901 cagatttcac aaaaggacac ctgatctcat acagtgtcct tttttctgaa ttctcttcaa
    60961 aagactctcc ttattctatc agctgacagt ttctctatcc tctagaaaaa ggtattctaa
    61021 aaatatctat aaagcatggt acactttctt taaatgaatc aatgcaaaaa acaagagagt
    61081 catcagttta cacgatcaaa agagatagca ggccgcttcc tttttcaatc ttatagatag
    61141 accatgggta acgataaaaa caaaaaagaa cttgcgactt attttgccgt aagttctttt
    61201 ttagctagtg ccttaatctc ttaatcccaa caaacgtctc gcatagatca cctgaccaga
    61261 gtgcatagca gcatcatcaa taatagaaac gagacgcatt cctcgtgtga ctggtggtgt
    61321 ccagttctcg tcaattactt catctagctc ggaaggttcc agccttctta agtaagaaat
    61381 agcaaaatca gcagctcctc gcaagtatcc tagcagatct tctatttgat tagcttggat
    61441 ctgctttgct tgttccagac tatgcttcca atcttgttcg ttatctgcta tcgtcatcgg
    61501 aaaccggctt tcccagtctt gactatgcca aattggagaa gttcctgcta aatcagcaat
    61561 ctggaaatct aattctcgag cggtatgcca agccagccaa gtcattgatt tgatctgcgg
    61621 ggctctatct tccactggaa aacgattggc ctcctcaata gagacgcctt caaacaaacg
    61681 ttcaaaccga tcgtatgccc gatccacact ctcgcatagc atatctaaat aatccattta
    61741 ttttcctcct ttttatttat cctacttact ttttcctaat tctaggatac ctacttatat
    61801 gttactacac acccttattt tttacacttt aacagtcacc atcatcaata gtttggagat
    61861 tgaaagaaaa agatagtgtc gaactatcaa ttgaacaaga agcaacaata tgaacgtttc
    61921 attaatattc tttaaataaa caatgatttt tcaaacgaac agtttaagac taggagaaaa
    61981 agagtataat aggaaaatgt ttgaaaggaa aggaagggga aaaatgaaaa aaagggcaag
    62041 tttactagtc ctagttgctt tgttgttcaa tatcttttcg tatggtgtgg ccgtttcagc
    62101 ggaaacatac attcctaaag accctgggaa tatttataat gatctaactg gtaactatgg
    62161 cttgttagga attgctagtc aattccacgt atttgctaaa aataagacaa ctgtgaatgc
    62221 acatacagac ggaaatatag caacacatga acttgatgca aaaaataatt ttggtacaga
    62281 gcttcatgaa ggtttattga accaagaaat aaattatata caaaaaactg attctttcgc
    62341 taattcttca ggcataccta caggtagcac aagaatgaat aaatttgtcg ttggcagtaa
    62401 cgtggatgta gcacttcaag atggtcatcc tacagtcaat ggatccaggc ttgatcactt
    62461 aactccagat gatttttata aagatcgtgc tgggcatgaa tatattgatt tcgagcagga
    62521 atttgctaaa ttgaatgtag cagcaaatga tcttgcaacg atcactccag ctaaaacata
    62581 tactgctgca gattttccag acatgaacaa tcggacaatc gatttaactg atttatcaga
    62641 taccgggttt ttattggtaa atatcgatgc agaagtgtta acgatgaata cgccacttca
    62701 aatcattaat ccaaatgatc aagtagttgt atttaatgtc atcaacagtt cttctgcatt
    62761 gaacgtacag tcaccaatca aatacaatga tcgttcaaat catgaaacag aagatttttc
    62821 ggatgcgaat atctcttgga attttggaaa tgagatgact gatttgacaa tcagtgctcc
    62881 ttttcaagga acaatccttg cgcctaatgc tactatccgc attactcaaa accaagacgg
    62941 aacgattata ggaacaaatg tgattttaga tgcagctacc aatcgttggg atcctaacga
    63001 aatatttatc agcgacaatg gtacagatac gacagacaca agcgacagta cagatacatc
    63061 taccacaagt gatagctcag attcatcaac ttcaagcgac agtacagata ctacctctac
    63121 cacaagtgat
//
LOCUS       DAPBBR010000011        58813 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPBBR010000011 DAPBBR010000000
VERSION     DAPBBR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 58813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.011"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(96..1115)
                     /locus_tag="RD488_000699"
     CDS             complement(96..1115)
                     /locus_tag="RD488_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7656796.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1137..2144)
                     /locus_tag="RD488_000700"
     CDS             complement(1137..2144)
                     /locus_tag="RD488_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7656797.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2137..2802)
                     /gene="pgmB"
                     /locus_tag="RD488_000701"
     CDS             complement(2137..2802)
                     /gene="pgmB"
                     /locus_tag="RD488_000701"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7656798.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2795..5089)
                     /locus_tag="RD488_000702"
     CDS             complement(2795..5089)
                     /locus_tag="RD488_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7656799.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5349..7514
                     /locus_tag="RD488_000703"
     CDS             5349..7514
                     /locus_tag="RD488_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7656800.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7818..8651
                     /locus_tag="RD488_000704"
     CDS             7818..8651
                     /locus_tag="RD488_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDT7656801.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8753..10453)
                     /locus_tag="RD488_000705"
     CDS             complement(8753..10453)
                     /locus_tag="RD488_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656802.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10960..12120
                     /locus_tag="RD488_000706"
     CDS             10960..12120
                     /locus_tag="RD488_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7656803.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12136..12579
                     /locus_tag="RD488_000707"
     CDS             12136..12579
                     /locus_tag="RD488_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7656804.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13062..13592)
                     /locus_tag="RD488_000708"
     CDS             complement(13062..13592)
                     /locus_tag="RD488_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HDT7656805.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13697..14248
                     /locus_tag="RD488_000709"
     CDS             13697..14248
                     /locus_tag="RD488_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7656806.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14401..14874)
                     /locus_tag="RD488_000710"
     CDS             complement(14401..14874)
                     /locus_tag="RD488_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7656807.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15012..16484
                     /locus_tag="RD488_000711"
     CDS             15012..16484
                     /locus_tag="RD488_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7656808.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16481..17191
                     /locus_tag="RD488_000712"
     CDS             16481..17191
                     /locus_tag="RD488_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HDT7656809.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            17543..17827
                     /locus_tag="RD488_000713"
     CDS             17543..17827
                     /locus_tag="RD488_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HDT7656810.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18108..18527)
                     /locus_tag="RD488_000714"
     CDS             complement(18108..18527)
                     /locus_tag="RD488_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HDT7656811.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(18529..19113)
                     /locus_tag="RD488_000715"
     CDS             complement(18529..19113)
                     /locus_tag="RD488_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDT7656812.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(19160..20635)
                     /locus_tag="RD488_000716"
     CDS             complement(19160..20635)
                     /locus_tag="RD488_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDT7656813.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            20816..21127
                     /locus_tag="RD488_000717"
     CDS             20816..21127
                     /locus_tag="RD488_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656814.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(21242..23578)
                     /locus_tag="RD488_000718"
     CDS             complement(21242..23578)
                     /locus_tag="RD488_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7656815.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            23720..24388
                     /locus_tag="RD488_000719"
     CDS             23720..24388
                     /locus_tag="RD488_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7656816.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            24391..25434
                     /locus_tag="RD488_000720"
     CDS             24391..25434
                     /locus_tag="RD488_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7656817.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(25671..26552)
                     /locus_tag="RD488_000721"
     CDS             complement(25671..26552)
                     /locus_tag="RD488_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7656818.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            26711..27439
                     /locus_tag="RD488_000722"
     CDS             26711..27439
                     /locus_tag="RD488_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDT7656819.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            27595..27912
                     /locus_tag="RD488_000723"
     CDS             27595..27912
                     /locus_tag="RD488_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7656820.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            27905..28513
                     /locus_tag="RD488_000724"
     CDS             27905..28513
                     /locus_tag="RD488_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDT7656821.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            28568..29359
                     /locus_tag="RD488_000725"
     CDS             28568..29359
                     /locus_tag="RD488_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDT7656822.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            29497..30009
                     /locus_tag="RD488_000726"
     CDS             29497..30009
                     /locus_tag="RD488_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDT7656823.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            30035..30907
                     /locus_tag="RD488_000727"
     CDS             30035..30907
                     /locus_tag="RD488_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7656824.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            31083..31445
                     /locus_tag="RD488_000728"
     CDS             31083..31445
                     /locus_tag="RD488_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7656825.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            31454..32206
                     /locus_tag="RD488_000729"
     CDS             31454..32206
                     /locus_tag="RD488_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656826.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVKPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            32220..34022
                     /locus_tag="RD488_000730"
     CDS             32220..34022
                     /locus_tag="RD488_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656827.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            34299..35339
                     /locus_tag="RD488_000731"
     CDS             34299..35339
                     /locus_tag="RD488_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7656828.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(35391..37535)
                     /locus_tag="RD488_000732"
     CDS             complement(35391..37535)
                     /locus_tag="RD488_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7656829.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(37892..39265)
                     /locus_tag="RD488_000733"
     CDS             complement(37892..39265)
                     /locus_tag="RD488_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7656830.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPIMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(39265..39660)
                     /gene="rbsD"
                     /locus_tag="RD488_000734"
     CDS             complement(39265..39660)
                     /gene="rbsD"
                     /locus_tag="RD488_000734"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDT7656831.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(39688..40605)
                     /gene="rbsK"
                     /locus_tag="RD488_000735"
     CDS             complement(39688..40605)
                     /gene="rbsK"
                     /locus_tag="RD488_000735"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDT7656832.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(40714..41727)
                     /locus_tag="RD488_000736"
     CDS             complement(40714..41727)
                     /locus_tag="RD488_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7656833.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(41808..42410)
                     /locus_tag="RD488_000737"
     CDS             complement(41808..42410)
                     /locus_tag="RD488_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7656834.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITKYNPSAFFGTSLDLQLRRRGIETIVLSGVATTNGVYATALDAFQHGYHVVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            42595..43296
                     /locus_tag="RD488_000738"
     CDS             42595..43296
                     /locus_tag="RD488_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656835.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            43306..46017
                     /locus_tag="RD488_000739"
     CDS             43306..46017
                     /locus_tag="RD488_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656836.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKVGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEHNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWSYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            46414..48042
                     /gene="treC"
                     /locus_tag="RD488_000740"
     CDS             46414..48042
                     /gene="treC"
                     /locus_tag="RD488_000740"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDT7656837.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRITIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(48102..49283)
                     /locus_tag="RD488_000741"
     CDS             complement(48102..49283)
                     /locus_tag="RD488_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7656838.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            49535..51061
                     /locus_tag="RD488_000742"
     CDS             49535..51061
                     /locus_tag="RD488_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7656839.1"
                     /translation="MKRLIGILAMLVLAGMLTACGGASGKAEDSKEKLSVMTTFYPMY
                     DFTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQK
                     TLQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVAN
                     IRDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLAL
                     EYGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGV
                     SLEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNG
                     YFEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGY
                     QTDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGA
                     FRYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH
                     "
     gene            complement(51130..51858)
                     /locus_tag="RD488_000743"
     CDS             complement(51130..51858)
                     /locus_tag="RD488_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7656840.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(51871..53151)
                     /locus_tag="RD488_000744"
     CDS             complement(51871..53151)
                     /locus_tag="RD488_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7656841.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILTSCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYAQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(53292..53894)
                     /locus_tag="RD488_000745"
     CDS             complement(53292..53894)
                     /locus_tag="RD488_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7656842.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            54140..54346
                     /locus_tag="RD488_000746"
     CDS             54140..54346
                     /locus_tag="RD488_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656843.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            54659..55378
                     /locus_tag="RD488_000747"
     CDS             54659..55378
                     /locus_tag="RD488_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7656844.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(55459..56142)
                     /locus_tag="RD488_000748"
     CDS             complement(55459..56142)
                     /locus_tag="RD488_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDT7656845.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            56374..58560
                     /locus_tag="RD488_000749"
     CDS             56374..58560
                     /locus_tag="RD488_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDT7656846.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        18865 a        10461 c        11873 g        17614 t
ORIGIN      
        1 ttttacagat aaacaatgtg ttagaagtag tatcttcttt tacataaaaa gctgaccata
       61 ggataaatgg tcagcgtatt tagtgagtca gctatttagt atgggttttc taaaggaacg
      121 actgtctctc ttttgatcaa gcgatgaggg atgaccaaac gtacgccact gctcaattct
      181 tcatggatca attcgcgcag cttttgcata gcgacacgtc ctaattcgga gatatcgata
      241 tcgatacttg taaggtaagg gtgtgttaat gttgagaaga tcgagttgtt gaagctaatg
      301 acggagagtg tctctggaat gacatagcca tacatttgcg ccaactgcat cgtgcgaagg
      361 gcgaagatat cgtcaatgac caccaatgct gtggcttcgt tttctttcaa cgttttctca
      421 aaggacagat aatcctccgg atgctctagt actacactgg ataacgcagg aagaccagcc
      481 atcatcattg ctttttgata accgaaatat cgttcgaaat acaaactttc atgagtcgtg
      541 tttgtcacaa acaggatatt cttatgtcca ttctggatca aaaattctgt tgcttgttta
      601 cctagaagct ggttatcatt atctacataa acgatttcgt tctcatgatg ataaggctgt
      661 ccgatcaaag tgaaagggat gtggttttgg tataaataat caatgacagt atcttgacta
      721 tctgaataca ctagaataaa accatctact tgtttttgta aatgcatacg ctggacgttc
      781 tctaacagca attcaaaatt tttagcagta gcgattgctg tagtcatatc ataattccgc
      841 gcttcttcgt tgattgcttc catgatctca agataaaatg ggttaccgat ccgctctttt
      901 gaatcaagag ggggtaagat tacgccgatg gcactggaaa tgcgttttcc tagattgcgg
      961 gcagtcatgt taggaacata acctagttca tccataattt ttcggacttt cttctttgtt
     1021 gtctcggaaa tactaggatg atcgttgatg acacgagaga cggtcgaggt ggcaacaccg
     1081 gcttttttcg ccacatcttt tacggtaata gccatgataa aaacaccttt ctcttgttat
     1141 tgtgcagaga accgataaat cgtctgactg atccgttctt gaccaggatg gaggttgatc
     1201 gatccaaatt tggggaaatg aacgatatca gggatttctt gcggttcgat tgctaatccg
     1261 tagtttgaat gcatctgttt tccattgaca gagaaatcag cttcgaatcc agtcgtagaa
     1321 aataatacca tacttttatt agaagttgct atagtcattt ggcgaccaga atgcttctcg
     1381 aataattgta aggaagtttt ggaaagccta ggatgatgca aaagaaatac atcatctagt
     1441 ccatctggat aacatgcaag gatctcttgc agtgttgggg attttctaaa gtcgattggc
     1501 agtttttctt tttttgtcca atttccagta ggcagttttt cttgatctaa ttcaagcaca
     1561 ccatctaaaa agaccgttaa ctgatgttca tagatgtctc ttgttccatt tcctgaaagg
     1621 ttgaagtagg catggttggt cggattgcag atggtttcaa caaggctact agcagaggtt
     1681 gtcatctcta attcgttttt tgttaaacgg taagtgatcg tagcagtgat tggtcctgga
     1741 taggtagaaa attcatcttt taagtaaaag accacaccta ttgatgatgg agttttgaaa
     1801 acttctactt cccaaaattg gaaagaccag cctttcgtgc caccgtggat atggtgtgat
     1861 ccgcagtttt tctccaatct atgctcaccc caagaagcat cccggatcct tccggctaca
     1921 ggtccgacag ttgctccaaa aaagcttttg tctgttagaa catcttcgaa acgatcgtaa
     1981 gacaataaaa cattttctga ttttccttct ttgtctggtg cgaagatttg gtgcaggcgg
     2041 gcaccgtaat tgagaagaac gacttctaag tagtcgttct tcaatgtgat tttctttatt
     2101 tcagtctctg gaactggtac gacggagatc tctggattat ccatggtcat gccacttttc
     2161 tttcaagtaa tcgatcgtaa gaaaagtcgt atcagggaca agcgggatct cctctccaag
     2221 gtcttcagca cgtcccacgc caattggttg agcgccactt gagaggatgg cttggatacc
     2281 ggcttgcgcg tcttcgatcc cgatacattc ttctgctttt agtccgacag cttttgctgc
     2341 aaggaggaag atatctggcg caggttttcc gtttgttgct tctgccgggt cggcaatagc
     2401 atcaaagtaa ggtgtaagac ccattttttc aagtaggaat ggcccgtttt tacttgcaga
     2461 agcaagagca atcttgattt tttcttcttt taaagaatcc agtaaaggca cgaccccggg
     2521 gaagacatct tttggttcga tcgtctggat catctctaaa taataatcgt tttttctttt
     2581 cgctaattct gcaaattctt cctttgaaaa agagtgttct tttccgccat aagctaaaag
     2641 caaagagagt gagtcttctc ggctgacgcc ttttagctgt tcgttgaatg tgtggtcgat
     2701 cgtaatgccg atttcctgac caagctttcg ccaagcacga taatggaatt cagcagtatc
     2761 ggtaatgaca ccgtctaaat caaacaatac ccctttaaac atttgcttcc tcctttctta
     2821 gcgttatttc tagacgatcc gctaaagaat aagactgttc atagacgtaa atttctagag
     2881 gagaaccttc taataactcg aaagtaactt gttcatctgt gactgagatg aacaataaac
     2941 gtccgcgata attgatatgg aaagaataag ctttccaagt ttttggcaga aatggtgcga
     3001 atctcaactg atcatgggca gttttcattt gagcaaatcc ttggacaatc gacaaccagc
     3061 taccagtcat ggaagtgatg tgcaagccgt cttctgtgtc gttattgtaa ttatccaaat
     3121 ccaagcgagc tgttcgctgg tacatttcta cagctttgct ttccattcct aattctgctg
     3181 ctaaaatcga atggatactt ggcgaaaggg aagactcatg gacagtcatt ggttcataga
     3241 aatcaaagtt tttttgcttt tcttcttttg taaaagtatc attgaagaaa taaatcccct
     3301 gtagtacatc tgcctgcttg atgaagcaag atctaaggat tttgtcccaa gaccaatgct
     3361 gattcagagg aagatcgctt gtgggaatat cggatacagg catgagatct ttatctaaga
     3421 atgtgtcatg ctggacaaag attcctaatt cttcgtcaac tgggaagtac atgttctctg
     3481 cgatatcttt ccatttggct agttcttctt cgctgatagt gatagcagct tctttttgat
     3541 aagttaaata attttctcgc gtgtaacgca agacccaagc tgcgatcgta tttgtatacc
     3601 aattgttatt gatattgttc tcatattcgt ttgggccggt cacaccgtgg atcatgtatt
     3661 tatttgctcg ttttgaaaaa tggacacggt ctgcccagaa gcgtgcgatt tctgctaaaa
     3721 cttccagtcc ttcatttttc aaatattccg tatcgccggt gtaattcgta taattgtaga
     3781 ttgcataggc aatcgcgcca tttcggtgaa tctcctcgaa tgtgatttcc cactcgttat
     3841 ggcattcgac accagtgaag gtgaccatag gataaagcgc gccttttaat ccttgttgct
     3901 gagcgttgtg gattgcttgc ggcagttgat tatgccgata tttcagcaga ttcttagtta
     3961 cttcaggttt ggctaaagca agataaagag ggacagcata cgcttctgta tcccagtaag
     4021 tggctccgcc gtatttttct cctgtgaatc ctttggggcc gatattcaat cgttcatctt
     4081 cgccgtagta agtagagaat agttggaaca aattgaatcg aataccttgt tgtgcttctt
     4141 cgtctccttc gatgaccaca tcggcaagct tccatcgttc tgcccaagcc gctgtttgct
     4201 cttcttttgc ttggatataa ttgtttgtct ggttcgttaa ttctgagaca gctttttctg
     4261 cttgctgcgc ttctggaata tctctactag taagaacgat aatttctttt tccactgacc
     4321 atgtctcacc ttgagataat tctgcagaca agcaaccatg taatgctaaa gtatcttcgt
     4381 gatagtcagg gatgactgat tttccattaa cgaaatggcg cattgctgca gtaacagtaa
     4441 attgttcaat cccaaagttg tttggaatag ttttagtcgt caaatagccg atttcttcta
     4501 tagttccacg atcaatctca ttccaaaaat gttcatcata gttgctgtct tcgttttgaa
     4561 catttccatc caattttgat acgagtttga ctgttccgct accttcaagc atttctatag
     4621 ttaaatagat ataagctgat tcttttttga caatgctcag aaaacgttcg aaggaaatgc
     4681 gtactttatt agtagaagta gtgattgtga atgtacgaga taatacacca tttttcatat
     4741 ctaattccca gtaaaagtct tctggttcca aagaagccaa gtcgatcagc tgatcgttga
     4801 tcgaaatatc tatcgcgata aagttcaagg cgttgatcac ttttccaaag tattctggat
     4861 aaccattttt ccaccagccg acacgtgtct tatcgggata ccagacaccc gccaaataag
     4921 taccttgatg gtggtcccct gagtaagttt cttcaaagtt cccgcgcatc cccatataac
     4981 cgtttccaat acttgttaaa gattcttgca gtcgaagatt ttttttatct aattgtgtcg
     5041 tgctgatttt ccatggatca atagcaaata gtcgtttgat ctgtttcatt tttctcctcc
     5101 taatgagctg ttttatacgt tcataataaa cgcaaccgat tgcacaagtc aatagacaaa
     5161 agaaaatatt tcatagaaaa aagcttaaaa aaataaattt ttaggagaaa attatagaag
     5221 ggaacacacg tattataggt tttatagaat ggtatagaca gaaaaataaa aaataaagca
     5281 tttacaaaaa agaaaacgca cgctataata cgtttaacga aaccgattgc gtaaaggagc
     5341 taaacggaat gaaaaagata tttagttttg aattttggca aaaatttgga aaggctttaa
     5401 tggttgtggt agcagttatg ccggcagctg ggttgatgat cagtataggg aaatcaattc
     5461 ccttgatcaa tcctgattgg acgccgcttg tcacaacggg cggagtaatt gaaaatattg
     5521 gttgggcaat tattggtaat cttcatattt tatttgcttt agcaatagga ggaagttggg
     5581 caaaagaaag agcaggcgga gcatttgcag ctgggatctc atttatttta atcaatcgga
     5641 tcactggggc tatctttggt gtcacaagtg acatgcttgc gaatgaagat gcatttaccc
     5701 acactctgtt cggtacgaag atcatggtta aaggattttt tacaagtgta ttggaagcac
     5761 cagctttgaa tatgggagta ttcgtaggga tcatcgctgg atttgtcggg gcaatggctt
     5821 ataataaata ctataattat agaaaattgc cggatgcttt gtcatttttc aatggaaagc
     5881 gctttgttcc gtttgttgtt atcttatggt caacaatcgt ggcattgatt cttgctgtgg
     5941 tgtggccaaa cgtacaggct ggaatcaata attttggttt atggattgca gaatcacaag
     6001 aaagcgcacc gattctagca ccgtttttat ttggaacatt agaacgttta ctattgccat
     6061 ttggattgca tcatatgctg acgattccta tcaactatac acagcttggc ggatcgtatg
     6121 agattttatc aggcgcacag gcggggacac aagtatttgg gcaagatccg ttatggttgg
     6181 cttgggccac tgatttagtg aatcttaaag gtgcagggga tatgtcgcaa tatgagtttg
     6241 tgttgcataa ctggacgccg gctcgtttca aagtaggaca aatgattggt tcttcaggta
     6301 tcttgatggg aatggctttt gcgatgtatc gtaatgtcga tcctgataag aaagcaagat
     6361 ataaatcaat gtatttttca gcagcgttgg ctgtctttct aacaggtgta acagaaccat
     6421 tggagttcat gtttatgttt gctgctgtgc cattatatgt catttattca gtgatccaag
     6481 gggctgcatt tgcgatggca gatatcttgc cattgcgggt ccattcattt gggaatatcg
     6541 aattgctgac tcggacaccg ttagctatca aagcgggtct aggtggagat cttatcaact
     6601 tcgtgttgtg tgtgatcgct tttggtgttg ttacgtattt cttagcaaat ttcttgatca
     6661 aaaaattcaa ctttgctaca ccgggacgta acggaaatta cgacaatgac agtgaagaaa
     6721 ccgttgtatc taacagcgga acaggaacag cagatcagca agtggtccag atcattcatt
     6781 tgctgggagg aaaagaaaat atcaaagatg tcgatgcttg tatgactcgg ttacgcgtaa
     6841 gtgtaaatga tcgagaaaaa gtagggactg aagaagcctg gaaacgagca ggggcgatgg
     6901 gattgatcgt caaagacaat ggagtccaag cagtttatgg accaaaagca gatgtcttga
     6961 aatcagatat cgaagatctg ctgcaatcag gagcagagat tccagagcca gaaatggttt
     7021 ctacaggaaa tggacaagca ggtagtaagc aatacttagg tatagaacaa gaactagttt
     7081 ccgcagcttc tggagaagtg attcctttat ctgaagtaaa agatccggta ttctcacaaa
     7141 aaatgatggg tgacggcttt gctgttattc caacatcaag agaagttgtt gcgccgatcg
     7201 ctggaaaagt gacaagtatt ttccctagca aacatgcaat tgggctggaa acgaaagatg
     7261 gtatcgaagt tttgatccat atgggaatcg atacagtcca aatgaatcag ccagcttttg
     7321 agattgctgt caaagaaggc caagaagtag gaacaggaac gaaattagct gagatggatc
     7381 ttgatgtgat ccaaaacgaa gaaaaagatc caacgatcat gatcgtattt acaaacgata
     7441 aagtagaaga agtagtgatc aagcaattag gtacagtgac agctggtaaa gtgatcggct
     7501 ccattaaaat gtaaggagag gttgtgaaaa agctgtcctg catcaagtca taagaacagc
     7561 caaacaaaaa tagctcctcc tatttttcgt ttggttgggc ttattaccga gaagcagcag
     7621 tttgaatact gtttagtgga gaggtcgtga aaaagctgcc ctgcaccaag tgataaaaac
     7681 agccaaacaa aaaatagctc ctggtccatt gagcttatta ctgaggagtt agcaggagaa
     7741 cactatttgc tggagaggtt gtgacaaaaa ttttgtcaca acccttttgt ttcgaaatga
     7801 agacaaggag aaaaccaatg aaattcatga cactcaacac gcatagctgg cttgagccag
     7861 aaccagagaa aaaattgcaa gaattagcag ataagatcct gttagaagat tatgaagtga
     7921 ttgctttaca agaaatcaac caattactgg aatctgaaga agtagaacct gcgaagctaa
     7981 tgaagttctg tccggtaaag aatcaagtac ctatccgtaa agataatttt gcctaccgtt
     8041 tagttcagct tttaaaggaa cacggaaaag agtatttttg gagttgggaa atgagccaca
     8101 tcggttatga taaatatgaa gaaggaaatg cactgcttac gaaaaaaaca ttggaaagtc
     8161 aggtccttac cgtctcccaa tttcaaaaga aagaagatta tcagacacgc aagatcttga
     8221 ttgggaaaac aaagatagat gatcaggaca tttttgtctc gagctgccac ttttcttggt
     8281 ggacagataa aaaaagtggc ttttattttg agtggaaaaa cttggaaaac tactttttgg
     8341 aaactcgcgt accacttttt ttcctaggtg atttcaataa tccagtagac tctcaaggtt
     8401 attatactgt aagagaaagt tgccttcttc ttcaagattc gtatgttgtc gcgaatgaaa
     8461 aaggaaaagc agctactgtg gaaaagaaaa tagatggttg ggaacaaaat acagaaaaat
     8521 tgcgtataga ttttattttc gtccctgaag gaatgcaggt taaaaaatat caacggattt
     8581 ttgatgggat cgatagtcca atcatcagtg atcactacgg ggtggaaatc gaattagatg
     8641 tgaacgaata aaaaatataa catataacat aaaaaaactg attaaaataa aactctccaa
     8701 acgattatac cgtttggaga gttttttgat cggatgtatt tatccctttt gcctaagcac
     8761 gtaaaagctt gtatctatga taaataaata aacatagcaa ggtaaaccag ccaatcaaag
     8821 taagagaaag aatgaaatag aaatagattg gcgtttgata atgaagcgtg agctcgttga
     8881 ttcctttttg ctgcttcacg attggggtcc cgatatctgt tacttcataa tcagtcaatg
     8941 tttttccatt ttgctgtagc acagtccgat cgtagacgat aacagggata tgaacagttt
     9001 tgtccccagt gtttttccac ttgattgtca aaagaccgcc tggatgtgtt tttataaaag
     9061 ttgtttcgtt ttctagtatt tcttcgttat accggtcgta tttattgtct tttgtctcct
     9121 tatagattgg cagatagtca ggtgtggttt tttggaaaac gaacaagctg gtagacatat
     9181 ctttgctgaa gaatgttttc cttgcttctt ccggcgtatc gaatagataa gtatgtcgac
     9241 tgacaaatgt ttcattttcc cacttttcca gatgctggta taagttctgg atcgtctgtg
     9301 ctgaaaaaat aagaatgcca aatatactta aaagacggaa ccacttttgt tcagaccact
     9361 ggttcagtga aagggcaagg taaagtagaa gcaatagcgt aaatggcacg aaaaatcgaa
     9421 atggaaactg gatcaaacta ataaaaggca catttttttc gatcaatgtc gtccatggaa
     9481 tcaagctagt agaaagaaaa aagaaaacaa gacttgtgta caacacgatt ttttggaata
     9541 aggtgttctt ttgttgaaag aaaataaaaa gcaaaaaacc tgataatatc aatataggaa
     9601 aggccttagg gtaatggagc caataactgc catccagatc tatcgccttt tgactcattt
     9661 ctctgttaac aaagggagga agaatcttat tcccactgta aacaatagct aatcctgccc
     9721 aaatatttgc tgtcagaaca aaataaagca agaccgactt aatcagttga agcagtgctt
     9781 ttcctttttc agtctggtta aaaaagtaat aaagataaaa agggatatac atcaaagcta
     9841 acatgatcga agacagtaaa tggatctgtg tcataagtcc cactgagaca gcgactttga
     9901 taacagggaa ctttttatga aggacgaaat cagcaatagg gatcatacat aaaggataaa
     9961 aacaagtccc ccagctagtg aatccttggt tgatagacca gtattgaata gaatacgtac
    10021 tcatgaataa aacggctact ggtacactta cccaatttcg aacattgaca tatctcagta
    10081 aaatcagcat agaaaatcct gaaataagat aaagaatgaa atttgaaaga atctgataat
    10141 gaaaccagct acctgcaagc aacacgatca atccttgtaa ataagcgaaa aatgggccgt
    10201 aaacggcatt cacgatcctg ccactttgct ggaatccata aagggaagga aaataatgga
    10261 aatccccata tttaatttgt tgcgcggcat catagaaccg attgtaatgg aatggggcat
    10321 cagcacccaa aattagttta tgtgtgaata aatgaggcat gagaaatgcc aaagcaatga
    10381 aaaaaattgc taaaaatggg ccatattttt tcaattgtcg aactcctttg caaactttag
    10441 ataaattcat catatatcct atgcgagagg taggcaagaa attagaaaat tcatgaaaat
    10501 atttatgaat tttacaagaa aaacataagt gaaagttcta aggagagagg atgcgacata
    10561 agttttgttg catctccttg ttttgaaaca gaatttttct taatactcga aacaaagtag
    10621 ctttttcatg acctctcggt aaacggtgtt caatcagctg cttctcggta ataagctcac
    10681 tagcctagaa aatatgagaa gctattttct gactagcgct cttattactc aaagcataac
    10741 gcagttttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    10801 ccaacccaac aaaaaatatg agtagctatt tttttgggct gtacttatta cttgatgcag
    10861 gacagctttt tcacaacctc atcggctttc attttctatt tttttcctga acccatataa
    10921 taaaagaaag aacaaaaaaa cttgcaaggg aggacacatg tgaagcagag taagcaaaaa
    10981 cagtctcgtc gacttttgtt tcgtttgttt ttattaatat gtatcgtcgt agggttactg
    11041 atcgctttat atccatttta tgtggattct ttaaatagtt ttattgatca aaaacgtatc
    11101 gaacaagtac aaaaacggac cgcagctgaa attgaagtgc agcgaaagaa aatggaggag
    11161 aaaaaccaac gattaactga ccaaggattc aatcctggta ctgatccttt caatgaaaag
    11221 aacagaaatg aaagtacaac atccagccaa ttagaggaat ggctgatcgg aagtatcaat
    11281 atacctaaga tccaattaaa tatttcactt tatgatcggc tcaatggtag gatccttgaa
    11341 aatggagcag gcgtcttgca aggaacctct ttcccgcttg gtggaaattc gacgcattca
    11401 gtgatctctg ctcacagcgg tttacctaat cgacggttat ttaccgaatt agatcgttta
    11461 gaaaacggag acacgtttat tttgactgtt ttgggggaga aattggctta tcaagttaaa
    11521 aatatacaag tggtactgcc agatgacacg tctgttctaa cgatttcaga aggagaagac
    11581 ttagttacct tgcttacatg tacgccgtat atgatcaaca cgcatcgttt gctagtgaca
    11641 ggacatcgga ttccttataa cgaatcggta aaaaaagaag aaggaaaagg aaatcaggaa
    11701 agaaccatgc ggcaatggtt tattcttgca ggaacgataa tagctgtagt catactgtta
    11761 gtgtttatcg gacgactaat ctatcagtat agattaagta aaaaagtgct tgatttttca
    11821 tttattatta gtgattcgtc agggaaaccg gtaaatggta gttcattcat tttgaaacat
    11881 aagaaaaaaa cacttactag aaatggtgtg ccgttttcag tacaaagcga ccatcatggg
    11941 aaagtcaagc tggatcaatt gcctggtgga acttatcgaa tcgtttcagc tgatgatcct
    12001 aaagttgctg tttcttttgg tattagaaaa gtaaaacaag agaagatata cttttttgag
    12061 gggcgaaaac ttgtaaaaga gcttcaaaaa aatggttttt attttaaaat caatgaataa
    12121 gtaaggagag aaaaaatgat ccgcacaaca acaaaattgt ctgccaaaga actggaatct
    12181 gttctatcga tttggctgca tgctaacttg gattctcatg aattcattcc atcaacttat
    12241 tgggagaatc aagtagaatc tgttaggaaa gctttaccag atgcagtgat ttacttagca
    12301 gaaatagatc aagaaattat tggttttgct ggggtgattg atcagtttat cgcaggaatc
    12361 tttgtgaaaa gggaataccg gcaacaaaga atcggtacgc aactaatgaa aaaaataaaa
    12421 gaaaccaata aaacactgac tttgacagtc tatcaaaaaa atcaatcagc tattcatttc
    12481 tatctttcac aaggttttac aattcaaaca cagcaaaaag atgaagcagt aaatgaggag
    12541 gaacttgtga tgaaatggaa tcaaaacgct gatttttgat gaacagaata acgaaataat
    12601 gctcccagcc taattttttg ctgggagcat tatttcattt tgaagtcact aatttaactg
    12661 tgtgaatatg cagttgttac aatctttgat aaacggtgtt caatcagctg accctcggta
    12721 ttagctcaaa aaacggcaaa atatgaggaa ctatttttcc atttgtttct ctaatactca
    12781 ggtcaaaacg ctgatttcac aacctcttga taaacggtgt tcaaacggct gcttctcggt
    12841 aataagccca ctagcctaga aaatatgaaa agctattttc taactagcgt tcttattact
    12901 caaagcataa cgctgatttc acaacctctt gataaacggt gttcaatcag ctgaccctcg
    12961 gtattagctc aaaaaacggc aaaacatgag gaactatttt tccgtttctt tctctaatac
    13021 tcaggtcaga acgctgattt cacaacctct ctttcacaac cttattttac tcgtttataa
    13081 ttttcatcga agtattttcc gctacggata tcatctggca ttccatcgta tggttcttcg
    13141 ctaataacat cttcattgtc tatacctgca tcacccatat aagtgatcgt agcaaattca
    13201 ggaacaagta attttggata agtttcatat ttttcacgag ctgcttccat ttctgcgata
    13261 tgttcgtttt ggaaagtaac agtgatttct ggatgttctt caacccattt agggaaaaag
    13321 atcattccgt gaagtttctt ttcatttggc ataaagtcca atgccacgtc tgtccctgtt
    13381 ggctctgtcc aagtgatttt gaatacgccg tccgtcaatt taacgatatc agcttcttgg
    13441 tcttttaccc aacggccttt gaccattccg ccatggatac ggtaatcaac agtatggtca
    13501 tttttggcat accattcata ttcccaacca ttgtcatacg tatagataaa gtgagttcca
    13561 ataaaatctt ccaattcttt aaattctttc atgtttaagc atctccttat aaattaaaac
    13621 atgtaataaa ctacatgttt tcgattactc atttatgata gaatggattt aaagatttgt
    13681 caaggaggga aaactgatgg caagaaaaaa tacacttcga tatattttgt tagggttatt
    13741 aagtaagaag aagatgacag gatatgaatt gaatcaatcg ttcaaaaatg aaataggaga
    13801 attttggcaa gcaaaacata gtcagattta tcctgaactt gcaaaaatgg aagagcaagg
    13861 aatcattcag catcaagtag agatcacagg tgaaaaattg gaaaagaaag tttatgaatt
    13921 aacagaagaa gggaaggaac aattggcaga gtggattcat acacccacca atgaactacc
    13981 ggttaatcga gacgaatttg ttctgaaatt gtatttcgtc aaagacgtga atgatccggc
    14041 attagtagaa attattcagc agcagcgtga ccttcatgaa gaaaaacgac ttcatctatt
    14101 agagcgaaaa aaaacgatct ttcctactga aaaagaaaaa catgaaaatt acggacacta
    14161 cctgatttta gcgcatgcga tcaatcggga aacagaatat gcaaattggc taacagatgt
    14221 attagaagaa agtaaccgaa aaaaataaaa aaatatccga acagtgatgg agaattcctt
    14281 tctatatgaa agaaacgcag atcaccgttc ggatattctt atgttcaaac aggccttttt
    14341 tcaagtattt atgtagcatc tacttattaa aaagcttggt acttaggaga ttagtggcgt
    14401 ttagagttct tttaacaact gttcgtagtc agctttttca tcgacaggaa ggagcttgta
    14461 agttaattcg tctgtctcgt tgtcatgaat gatgtacatc ttagcattct cttctttgaa
    14521 gttaccgatt tgtaaaatcg tatagcgttc gtcgatcaat tcgatatctt tgattgcttt
    14581 tgaaaaaact ttacggacat ggtgcatttt cttttggcgg atttctgcct tttctgcagc
    14641 ttttgacaaa gtaaatccgt catctaaata ttttttgatc agttctactt ttatgactgt
    14701 aggtaaacga tattttctag gacaattcgc atcagcttcg atcgaacgaa tgaatccctt
    14761 ttgttcccaa taccttaatt gacgtggaga cacacctacg atatcactta attcactgat
    14821 gccaacaacc aattgatcat tttccaacaa acgtttaagg gaagccccaa ccatttttgt
    14881 cactcctttt gtcctcttgc ttcccttaat tatatccgta ttaacttatg tgtcaagtag
    14941 gttgacaaat agcgaattta ggactaaagt attctagtag tttcagaaaa aattcagaaa
    15001 gaaggagaaa tatgagtaac aaccaacccg tagatattta cggaaaacca tataatcgga
    15061 cacttttagt tgttgtctta ttaattggta cattttgtac cgttttgaat cagaccttat
    15121 tgacgacagc ttttcctaca ttgatgaaag ctttcgatat ttcagcgtct gatgtgcaat
    15181 ggttaacgac tggtttcttg ctagtcaacg ggatcatgat cccaataaca gcatggctga
    15241 tcaataaatt cagttcaaga aatttatatc tttctgccat gacgatcttt ttgatcggaa
    15301 cgattacttg ctttacagca cctaatttta gtacattact aatcggtcgt ttgatccaag
    15361 cttgcggtgt gggagtatcg atgccattat tgcaaaatat catgctatct attttcccgc
    15421 cagaaaaaag aggatcagca atggggatgt cagggatcgt tattggactt gctcctgctt
    15481 taggccctac attatctggt tatatcattg ataactacca ttggcgtgac ttgtttggta
    15541 tggtactgcc aatcgttgtt cttgtcttgg ttttagcatt cttcctaatg aaaagtgtta
    15601 ttccattgtc aaatcctagc attgatattt tatccgctat tttatcaacg attggattcg
    15661 gtagtttact ttacggattt tctagtgtag gagatgacgg ctggggaagc ttgaaagtaa
    15721 ttggtttctt agttgttggt gtgattttca tcgccttgtt ctcatggcgt caattacatt
    15781 tggaacatcc attcttggaa cttcgtgtat tcaaatcatc tacattcacg attgcagctg
    15841 ttttagctgg tgtaacaaat atggcgatgg taggggcaga aatggtcgta ccattgtata
    15901 ttcaaaatat tcgtggagaa tcagcattcc attctggctt gatgttgttg ccgggtgcat
    15961 tgatcatggg ggctatgatg cctgtgacgg gtgcgatttt cgataaatac ggcgcgaaac
    16021 gtttagccat cacagggatg ttcattttga cagcggcaac tgcaccattt gctttcttga
    16081 caaaaacgac tccagtttta tatatcgtga tcctttatgc gatccgtatg tttgggatct
    16141 ccatggtcat gatgccggta acgacttctg gtatgaatgc attgccaaat aacttgatca
    16201 gtcatgggac agcggtaaat aatacattcc gtcaaatcgc aagctcgatt ggtacagcta
    16261 ttttgatcag tgtgttgacg aatgtgacaa aagcaaatat cccaagcaaa tctgtattgg
    16321 ataatacgcc attagcttat aaagatcagg caatcaatgc cacactgtca ggttaccatg
    16381 ccgcgtttat cgtagcgatc atctttggga ttcttggctt tattattgcc tttttattga
    16441 agaaaaaaga acctgttcta atgaaagcgg gggataatgc atgattattg gagttttgat
    16501 tgtcagcttg cttgcttttg ctttaacgaa cgtgttcgct aaaaaaacat ggcaaacctt
    16561 tttatctttg attttcggac taatcttcgt cgcttcacta agtttgatcg tcgctaattt
    16621 gtccaatcac tttggaatgg aaaaagtaac ggaaacaaaa acagaaaaaa ttgtttccag
    16681 tgctgattcc caaggagcag atatgctttt gtataaagct ttagggaatg gaaaagaaaa
    16741 agtgtatctt taccgaacaa atgaaaaaca agaaaaacca aaagcaactg gtacggataa
    16801 cgaaacaaat aaagtagaaa agacagacgg cgatgctgaa aaagtgacga aaactactta
    16861 ttgggaatac aaaaacgaca tgtataaatt ctggttcaat attgctgata acaatcacga
    16921 atatgacagc cgagtgaata cattcaaaat cccagagaca tgggtagaat taagtacgga
    16981 ccaagcagcc aagttagctg aattagtgaa gaaacagcaa agtacgatgg aaagtgaagc
    17041 aaaagcttat gttcaagacg gtatggtaaa agcaatgact gaaaatccaa aaatgagcaa
    17101 agcagagcaa gaacaacgta cgaaagcctt agctgctgaa ttccaacaac aagcattcgc
    17161 aaaattagtg aaagaagcaa aaggcgaata atattttgaa caccatgtag gaggttgtga
    17221 aaaagctgct ctgcatcaag cagtaagaac aatcagataa aaatagcact ccatattttt
    17281 catctgattg ggcttagtgc cgtagatgca agcttttgaa caccgtttaa ggaagaggtt
    17341 gtgagcctgc cgtttaactc tgagtcacaa ggagcaattt caaaaaacag cttctcatgt
    17401 ttgttgacta ttgtgacttg tgaccgagga gttggcagga gaacaccgtt tattcgaaaa
    17461 aaggaactgc gacaagactt ttgtcacagt tccttctttt ttttgctatg ctatactaga
    17521 tgtaaaaaat aggagaaata aaatgaggga aatttattct tttgaatcaa aaatctatgc
    17581 ttccgaagtc ggcaagggcg gggcatatat tatttttccg tatgatataa gaaaagaatt
    17641 cggtgctgga agagttaaag tccaagcaac ttttgacaat gtgccgtatg aaggcagtat
    17701 cgtgaatatg ggcgtgaaaa atccagatgg ttcagtctgc tacatccttg gactacgaaa
    17761 agatattcgt aaaaacatcg gaaaagaaat cggtgatatt gtagcagtta cagtgaagca
    17821 aaaataaaag aggttgtgac aaaagacgtg tcacaacctc ttgataaacg gtgttcaaaa
    17881 gccagtttct cggtagtaag tcaaatttat gcaaaaatgt ggaaacccat gtttacaaaa
    17941 tttttcttac tactcgaaac gaagcggctt tatcacaacc tcttgataaa cggcgttcaa
    18001 tcagctgtcc ctcggtatta gctcaaaaac ggcaaaatat gagaagctat ttttccattt
    18061 ttttctctca tactcaggtc ataacgctga tttcacaacc tcttctttca taatggtttt
    18121 tcaccatctt tataataaac tggttctttg atatggaaat ctattttttc caaccaatct
    18181 aaaatcttgt aacctaactc ttctgacatc ggaaaagagg cgttgatttg tgcattggag
    18241 atatggtcaa catggatacc ggaagtgatc gtacaacttc ccggaacggc agttttgatg
    18301 atcacagcta ttttttcggc taagacatcg tctttatgga accgaccatc gtggctaggg
    18361 aaacgtacag tttgcatctc tgtatcacga gaaaatgtag tgactgttcc gatatgtggt
    18421 gtatctccgc ctgttaaagt gatcaataag tctttaccga ttactttaac agcagcttgg
    18481 atcgtgaaac ctagtttggt tacttcaact atcgtttctt tttccatatt aatcaccctg
    18541 ccaacgtttt gaatgctcat ttacaatttc aaattgatcc aaaagtttca ttgtatggtg
    18601 attaacaaga tcttggatcg tttgaggctg attataaaaa gcaggaattg gtggtatgat
    18661 ttgcacacct agtcgtgcta atttagtcaa gttttccaag tgaatggcat ttaatggcgt
    18721 ttcacgagga acaatgacta actttcgttg ctccttcatt gttacatcag cagcacgtgc
    18781 aatcaggttg tcgcctaaac caacagagat acctgcgact gttttcatac ttgccggtac
    18841 gatgatcatt ccatcggtca aaaatgatcc gctggcgaca gcagcaccta aatctttgtt
    18901 tgaataatgg taatcaaaca ggctttcgaa ttcagttagt gataagtcgg attccagctt
    18961 taagttctgt tttgcccatg gactgatgat tccgtgtgtt tctatcatcg gatattcttt
    19021 tagtttcttc actaggttga tggcataaat ggtgcctgaa gcgccactta caccaatcac
    19081 gatttttttc ttccgttgtg ccaattgttc cattttccgc actccttttt atgatgtcaa
    19141 aacagttgca gatcattcat tatttcaaat atttttccca atcttctact tcttggaatt
    19201 ttgcacgtac aaaatgttct ttcatatcga aaggaactgt accgtcaaag atagtttttg
    19261 cacttatccc acggaaacga atagagccag gattatattc tggtaattct gatgggtcca
    19321 atggatggtt cctcattcct gggatcacga tgatatcttt atctccttgg aaacgagtgt
    19381 tgaaagtcca aactacatcg ttcatgtcga aaatatcaac atcttcatcg actaaaatga
    19441 ctgtcttcaa ttctttgaag gctgataaag caagaatagc tgcttgacgc tgaatacctt
    19501 catccgcttc gttttcttta cggatttgca tgatggtcat caatttacca ccacctgcag
    19561 gaggattgta gacatttact acttttcctg gaatagcttt atcgaccaag gcaagaatac
    19621 ttgcttctgt aggaataccg gccatagata cgtgttcttc actgggacca atcgttgttt
    19681 gcatgattgg attgtctttt cggtgagtaa ctgctttgac tttcactact tgtacagctg
    19741 gattagcatc cccagtatag ccaggaaatt ctggcattgc ttttcctgag ttcgtgttga
    19801 tatcttcttg cattgtttca tttggcatga tttctgcttc aatgatgaat tcagcacgag
    19861 caatacccac ttcatcgact gctataccat caacgatttg aataggttcg ttacgcaaag
    19921 ctcctgcaca ccatagttca ttgtagccaa gtggagtggt aggtggttcg aaagtcgtgc
    19981 caatggcaat tgctggatct aaaccaatat tgatagtgat aggcattggt ttattcaagg
    20041 cttcgaattg tttttggaag tgaccaatgt ggcgtccgcc aggcatgatg tacataccga
    20101 tcgtatcttt atcttctaga accatacgat ggatcgttac atcgctcatt gttttttctg
    20161 gatctgatcc taagactaca cccattgtga tgtatggacc agcatcttca ggagtatttg
    20221 taggtgcagg caaaatgttg cgaatatcga agtctgcatc ggtagctaga tgaacgactt
    20281 cttgtgctgg agcgtctgct ttgtctactt tcacaggttt gattggattt tctacagcgt
    20341 ctttcaagaa acgaccaagt gttcgataat catggtgcaa aatttcacct acacgtttac
    20401 gactagccat tgttccgatg ttcacacgtg tgccggggaa acctttgata ttgttgaaag
    20461 tcatagctgg tccttcttga gtcggacgtt ttactgtacc gccagcaccg atataacggt
    20521 aaacaccaga taattctgct tcaggatcga tttcaatatc tgtttcgtga tattgacctg
    20581 gaagtgtttt tagttcttcg atgacttttc ttaaatcata cggttgatct gtcatgagag
    20641 attcctcctt agttgtcttt acctatctat agtaaaaggt gaaaaagagg aaaacaattc
    20701 aacttgttcg gtaaagtatt ctacaatgga atggatgcgt ttttttgata atagaataaa
    20761 ctatgatata cttatcacta aaagaaagcg catacttagt gttggaggaa ggaaagtgaa
    20821 aaaaatggag gagtcatttc ctaaagcagt aaaagtggaa aatatagcga atattttgaa
    20881 agttacattt gaaaacggag aagtaaaata cgtgaaatct cattggacag aagagataac
    20941 cgatgccttg caatttggaa aaaaaggaag aggaaaaaga aaaaatcttc tcgcactttc
    21001 tcgtaatatg tggattggga ctgaagtaac gattgaagca gatggaacag tattcataaa
    21061 tggaaaagac aggtatacgc cagaagagtt gtggtacaaa ggaaagaaaa gtataccaga
    21121 attataaaaa ataattaaaa aaaacagcgc gaaacaagga acatattact tcctcgtttc
    21181 ttgctgtttt ctactatttc agcgctctta tgactcaaat ctaaatgtgg ttgtcacaac
    21241 cttattctgc acgcaaagcg atagcggcgt cttttttcgc tgccattcgt gcaggaagat
    21301 gaccgccaag catcgtcaat atagtagaga cgatcactag aataatcgca tggacaggat
    21361 ttagttgagc aacatttttt agatccgtca tgttgtataa gatgctattg atagggaacg
    21421 tagctagcca tgcaataaac acacctaata tcccagaaga aatacctaaa atacacgttt
    21481 ctgcgtcaaa tacgcgagtg atgtcttttt tacgtgcacc taaagctttt agtacaccga
    21541 tttcttttgt ccgttcaatc acagatgtat aagtaatgat actgatcatg atcatacttg
    21601 ttactaaaga gatccctgca aaagcaataa ggacataagt gatagcatcc atcaatccgc
    21661 cagtcagttc agtcatcgtt ccagctaaat cagtataaat gattttatct tcatctgatt
    21721 tgcctttatt gtaatcatct agataatcca agatcttttc tttgtcttca aaattgttcg
    21781 gataaatcat gatacttgaa ggcaagctgt ctccacctaa ataactaagc aatgtttgtt
    21841 tggcattttc gtcaactttt tcagtagtta agacatttac accactgtct ctttgagctt
    21901 tgacgatttc tgattctttg ttttcgttga cgatttgagt cgttaattga tcgctataag
    21961 cgattcctgg agataagaga ttcattgtag aagaagattt cacgcgtagg atccccgaga
    22021 tcttcaattc atcagaagca ttctgataca tcgcatcata atctgtatta gggataaaat
    22081 tcccagttgg aagttttgta tagtaagtat tgttgtttac taatttgaat gttgtaccaa
    22141 cgatatcatc aaaatcaagt ttttcgtctt ctttcacatc aaatccaaga ttcttcaatg
    22201 cgttgatatt agtattatta ttgccgtcta cgatcagcac gacatctgtt gctgaggctg
    22261 gataacttcc ggcaagtaaa gaataattgt cttttaaaaa gttttctttg ctagtgtcaa
    22321 gctgtgtagg gaaacttgac actcccacac ctgtcatcgc tgacatcgta ctagataaag
    22381 aaagagattc cgtatcagga ttttgattcg agaagctgac aggctgtact ttgccattta
    22441 catcacgtaa aagattgatt cctgtagtac gggtaaatcc gatattatta cttaagttag
    22501 gatcgatgtc tgttacgtaa tcgacgtatg tttgatcaat cttattcgtg tgctgtgctt
    22561 tatcttcttc gctgactttt gcagtaatcg ttttgctgtc tggataatcc gctttgcttg
    22621 cacccaatcc ggcatcgtca cgagtctggt tagtcgttac cttagaaata gtaatcggaa
    22681 atttcgccat cgtttcagct tgcgtgttat cgatttgttt ttggaatcca gaagaaaggg
    22741 acagaacgat cgcgattccg atgatcccaa tactggaagc aaaggaggtc aagaaagtac
    22801 gtcctttttt tgttcggata ttgttgaagg aaagctttaa cgctgtccaa aaactcatct
    22861 ttgttctgcg taagttaaat tgatcatctt ttggtcgttc gatgtgagga tgggaatctg
    22921 ttaagatctt accatcagaa aattcaatga ttcgatctgc gtattgatgg gccagttcag
    22981 gattatgtgt gaccatgatc actaattttt ctttcgataa ctcttggatc aattccatga
    23041 tctggatact tgtttctgta tctaacgctc cggttggttc atcgcacaaa aggatatctg
    23101 ggtcattggc tagtgctcga gcgatggcca ctcgctgcat ttgtccacca gataactgat
    23161 ttggcttttt atgcatatga tttgtcaagc cgactcggtg caatgcatct tctgcccgtt
    23221 ttcgtttttc gtctttagaa acaccactta atgtcatccc aagttcaacg ttttcaataa
    23281 tgcctagatg accaatcaag ttgtaacttt gaaaaatgaa accgatagag ttgtttcggt
    23341 aggcatccca gtcactgtcc ttaaagtctt tagtagactt tccgttgatt accatatcac
    23401 cggaatcata attatctagt ccaccaatca cattcagcat agtcgtttta ccagaaccac
    23461 taggacctaa aatcgctacg aattcttttt gtctgaaagc gacagacaca ccatccaatg
    23521 ctttggtggt ggtttcgccg actttataat atttttttat atcttttaat tgaagcataa
    23581 tcacccttct cccgtattga aatattcggt atactaataa gtatatcaga acaatgatcg
    23641 tagtatacga aataaatgtt aactgaagat gaactacaag aaaaaatcta gaaatttttc
    23701 aaaaaacaga gggagatcaa tgaatcgtat tttagtagta gaagatgatc cgcaattaca
    23761 gttgctttac cgttctgtgt tggaacgagc gggcttttca gtcatcaccg cattgaatgg
    23821 agaggatgcg ctgaaaaaac tagaagcgac acgtatagaa ttaatcatta cagatatcat
    23881 gatgccgaaa atggatggct atgacttgct agactcatta cgtagcacca gatttgacac
    23941 acctgttcta atgattacgg caaaggccga ttttgaggat aagaaacgcg ggttcaaatt
    24001 aggagcagat gattatatga caaaacccat cgatgtcaat gagatgatcc tacgtgtgga
    24061 agcattgctt cgacgttcaa agatcaatta cagcagtagc ttgataatcg gacaaacaaa
    24121 attagagcta gatgcttata cagtgttaca agatcagcat tcgttgattc tgcctcaaaa
    24181 agaatttctg cttctgtata aattactgtc ttatcccaac aagatcttca ctcgccaaca
    24241 gttgatggat gatatttggg gattagatac gaatacagaa gaacgaacga tcgatgtaca
    24301 tatcaaacgt ttaaggaccc gttttgaaaa gacggaagat tttcaaatca tcacagtacg
    24361 gggactaggc tataaggcgg ttatttaaag atgaaaaaaa agctattttc acaattatgg
    24421 atctattttg ctagtattgt cttcatttcg atcttagtga cactgctgtg ttttctcggt
    24481 tttattttct tattgtctcg acattctatc tcgcctgctg aatcggctgg aaaaccaacg
    24541 ttatacccgt tattcgtctt tgcggggttc agtatggtcg tgggtacagg aatatcgatt
    24601 tttgttgggc ggcgtatcct gcatccaatc agtgcgctag ggacaaatat gagtctggta
    24661 gcaacgggag atttttcgat tcgaatggat gaacagcaga aagtagcaga agtacagcaa
    24721 ctgtataaag atttcaacgt tatggtccaa gaactcaata gtatcgagac actgaggaat
    24781 gactttgtgt ccagtgtatc ccatgaattc aaaacaccac tagcaacaat ccaaggatat
    24841 gttcaattgt tacaagcccc aaatctctct gacgaagaac gccaaatatt tttatatcgg
    24901 attatcgaaa gtatcacgca gctttcacaa ttaacagaga acatcttaaa attgaacaaa
    24961 ctggaaaacc agcgtatcca actggaaaag aaagagtatc gattagatga acaaatcaga
    25021 gaagtaatcg ttttttttca gcctaaatgg gagaaagaac agctagaatt ggatatcgaa
    25081 cttgctgcag taaattacac aggcaatgaa gagtttttgt accaagtgtg gctgaatatc
    25141 atggataacg ccataaagta caatcaaatc aatggacaga ttcatatcaa actatttgag
    25201 acagccacag agattgtact ggaagtgacc gattcaggtg taggaatgaa tgaagagacc
    25261 agagatcgaa tgtttgaaaa attttatcaa ggagatacaa gtcgtcaaat ttctgggaat
    25321 gggctaggac tttcactggt taaaaaaatt ctagaactgc atgatggacg tattgattat
    25381 agtagtatcg aaggagtagg aacgacagca atgatacggt taagtaaaca ataggaaaaa
    25441 gaataaaacc cctaaaaatt ctattgaagg tttttagggg tttttagtcg tttttttgtg
    25501 attagggaaa tgttcttacg gttcttttgg cataaaaatc gctgctttct tattgaacta
    25561 cgagaaatgt tagaggtgtc attgaaacaa ggacatgatg caagaaagag agcgaaagtc
    25621 atgcgtcgct ctcttttttt gggtggatag atggacagaa aatgtagggc ttagttttct
    25681 tcttgattta aatactccca aaatgtatct gaagccaaag aatgctcacc gactttacga
    25741 gtaaatgcaa gataactctc tgttgttgga gaaataggga gaatcacagt attttctttt
    25801 aatagattct tgactgtttt ttccataaca atagcaatcc ccatgtcatt tgcaatcata
    25861 ttgatgatca agtcgattct tgctccttta taagagattt ttggttcaaa tccagcttcg
    25921 cgacacagat ctagtacagg ttgatacaag ttcgtagtgg ggccaaggag caaaaagttc
    25981 tcctttttca gttcgcttag atccaatttc tttttactag ctaaaggatg atttttaggt
    26041 agaactgcta caaaatcgtc tgtttcagta ggcaaccact caatcgaact tggtggggcc
    26101 tggaaacttc tagcaaagtg gatcgtgtca ctatgttcat tggcgtcatt gtaagttaat
    26161 tcgacacttt ccacttcttt caactggact gtaaattcag gatggcgttt caaaaactcg
    26221 gtgattttgg aaaaaccttt ataattgatc attgtcggta tcgttaagat atttaatgaa
    26281 agattgttgt ctttcgtata ggtttcaagc acttcttgca tagcatggta ttgttctacg
    26341 acatttttta catatgggag caataagctt ccagcttcgg tcaattcgat ttttctatgg
    26401 gcgcgttcga ataatttgac gtctaattct gtttctaacg aaagaatctg tttagaaata
    26461 tttccttggg tggtgaattg tcgatcagca gttttggtga aattcattgt ttcggctaaa
    26521 tcaagaaaaa cttcgaattt atggatatcc atcatattcc tcctacttat tccaataaag
    26581 aatactttaa cacaaaaaat gaattggtgt aatcttctct gtctgttaca atctttcttg
    26641 cagcgaaagc aataattaca gaaatttttc tgattttttt cgcttcgtag aaaaagagag
    26701 gagttttttg atgccaactg gagttttgat caatgtaggt tccgttttgt ttggcggact
    26761 aattggcgga ttagtaggaa ataaattaag tgaacatttt aaagcacagc tgacgatggt
    26821 ttttggtgtg tgttcgatgg ggatgggaat ctattccatt gcgccgatga aaaatatgcc
    26881 ggctgttatt tttgctttag tgataggaac agcgattggt ttgattgttc atttaggtaa
    26941 tgggataaat aagggggctg cgctgatgca agtacctatt tctaaaatct tccctagtga
    27001 aaagcttggt atgacccacg atgaatttat cagcacatta gtgacggtca ttgttctatt
    27061 ttgtgcaagt ggtacgggga tctatggaag tttagattct gggatgacag gagacagtac
    27121 gattttgatt tctaaatctg tccttgattt tttcacagca gctatttttg cgtgtaattt
    27181 agggtatgtc gtttctgtga tagcaattcc ccaattcatt attttttata ttttgttctt
    27241 attggcaaaa tttatttatc cattgactac accagacatg atcttagatt ttaaagcttg
    27301 cggcggattc ttgatggtcg ctaccggttt tagaatgatc aacgtgaaaa tgttcccagt
    27361 agctgacatg atacctgcaa tgatcgttat catgccactg agctggatgt ggacaaattg
    27421 gattatgcca ctgttataat aaaaatcaaa gagaagccat tttttgctga ctaaaaagga
    27481 tcaaatcttt tagtcagttt ttttgtattt gacaaactga ttttgaaact atattatatg
    27541 ttgtataata tagattgaaa taaaatatta cacttgagaa tagaaggtga cgtaatgcac
    27601 atccagattc caactgttct tcttgatggt actgtgttag cagcattaag caaggaagat
    27661 atgtatgggt atgccttaac aaaaatcgta caagaaagtc tctctgtcag tgaatctaca
    27721 ctatatccgg ttttgagaag gttgaaaaaa gaaggatatc ttgagaccta tgatgaacct
    27781 tttgaaggca gaaaccgtcg atattactcg ttgacaccaa tgggaagtcg tcatttagaa
    27841 gaaattattg atgaatggat tgtttttcga gattctttag accggttatt ggaggagagc
    27901 acaaatgaat gaatatttga atgaagttgt ggatcatctt caagaaattc ctgaagacga
    27961 tcgttttgat ttgatccagt attatgagga atatttttta gattctggaa aaacattaga
    28021 tcagatcatt gatgaatatg gtacaccaaa gcagtttgcc ttaaaattaa aaatcagtta
    28081 cttttcagaa gaagaacaag cagaaaacga gttagtgaaa aatccaaaaa gacaaattcg
    28141 cctgatttgg ttaatcatta tcggtttatt tgcttctcct gtcctcattc cactagcact
    28201 ggggtttata ttggttattg ggggactatt ggttgcttta ctagcgctca tttttagtat
    28261 ctatgtttta tgtatcagta tcttaggtgt tggcctattc atgatcatct caggaatcag
    28321 tgtgtttgga caatcgattc tgagtggatt attctttatc ggtgtcggtc tgttcgccac
    28381 aggaagcgca gtatttattt cgccactgtt gctgaaagga acaaaagggc ttttttatgt
    28441 catgatgaac tttgttaaat ggatgggacg acgttttatt acaaaaagag atctgcattc
    28501 agcgggcgtt tgaaggagga cacataaatt gagattgaaa cattttttga ttaccggtat
    28561 tggtctgatg cttactggtg gcctcctagc aggtgcaact tatacattag gcgctcaaaa
    28621 gagtctgact tgggataatg gtcctcggtt gatcgatatg gttactgaga caaaaaaaat
    28681 caaggatgca aacaaaatcg tcatccatgc agaaaatcaa acagtttcgg tcatacgcgg
    28741 attggatttt gagataaaaa cgacttatga taagacagaa aagccagaaa taaaggagaa
    28801 aaatggcgtg ttgactgtga atgcagtcaa aaaatcaaca ggtgcaatca ttagtttaga
    28861 agacacaagt gcacaaatca ctattgttgt ccctgcagat catgaattat ctgaattgac
    28921 aatcgaaggg aataatagtg caattgatat caacgaagta tcaatcaaaa aagtgaatac
    28981 taagacacat gatggctggg tatcgttcaa tgaatttaca ggaggaacaa taactgcgaa
    29041 agatgaatta ggctcacttc gactagatga ggccaatgtg gataacttga tcgtcacagg
    29101 tgaaaacagc aacttccatc tagaagacag tttgatcagc aaagaaggaa aagtcatcct
    29161 aaacggtggt aatttatctt tgcatgagat ggaaaacagt ggctatacta tccaaacgtc
    29221 tggtgaatct tatattgaaa aagactacca gccaataaca aatactttgt tagaacaagg
    29281 acagaaaaag ctaaagatca ctgctaaaga cacatcgatc aatattacga cggatcaaga
    29341 ggacaatgaa acagattgat cctgtactca actggatatt ttaagaaaaa acagcaaaga
    29401 tccttccaat ctttgctgtt tttcatcgct taacgcacat aactatagta aaataagaaa
    29461 gaaaatatct aaaaagaaaa cagggtgaaa gagtatatga aggtagaaga aggtcaaaga
    29521 gaaaagttaa agacagaaat ggaaagatta catacttata tcactcaact aagccaaacc
    29581 ttctatgatc cagacaaaga aaaagtgatg gttaattacc cgaacaattc agaaggtcgc
    29641 caattagagc aagtgtacca tgaagttttc aaacatttat tgacggtgaa gaaagagctg
    29701 gattattatt ctttaccgat tatcgataca ggaatattga agtatgatgg gaagaaggaa
    29761 cgatttatct ttaaatctgt tcgggaagat ttgcctcttt cagcagggat ggatctagag
    29821 gtcttggtag aagactattt tacagaagaa aagcactggg ttcgaacaaa attggattat
    29881 ttaccgcagg cagccggagg gacacaggca agcggttggt acatcactga agacaaagag
    29941 ttagaactag aaggtgtaat ggcgcgcatt cgaaaaaaaa ttaaaaaagt aacattagat
    30001 atttattgaa ggataaagga gcgcaggaag tagcatgaga gaaaaaagag cattttatat
    30061 caatggttat gcagggattg tcggattggt cgtattagct ttagttggat tgtttttctt
    30121 ctatttaggc atgtggcaag cgaaagtttg ggcacttttt ttaagtattt ttctttggtt
    30181 gatcacgtta ttgttgttaa gttcggcaac tgtagtcagt cctaatcaag caaaagtaat
    30241 tttgtttttt ggacaatatt taggtacgat tcgagaaaat ggctttttcc ttacgatacc
    30301 tttggcacaa aaaatgactg tttcgttgaa agttcggaat ttcaatagtt ctgttttaaa
    30361 agtcaatgat ttggatggaa accccatcga aatctcagca gtagtagtct ttaaagtcgt
    30421 tgatacagca aaggcattat tcgatgtagc gtattatcaa gattttgtag aaatccaaag
    30481 tgagacagcc attcggcata tcgctagcca atacccgtat gatacattca atgagaatga
    30541 tttgacgctt cgaggaaaca cgacggcagt gtctgacgag ttgcaaaaag agctgcaaga
    30601 gcgtttagca gtagcaggtg tcgaagtaat cgaaacacgc ttgaaccatt tagcctatgc
    30661 aacagaaatc gctagtgcca tgctccaacg tcaacaagca aaagccattt tgtctgctcg
    30721 acaaaccatt gttgaaggag ctgtcacaat cactcaaatg gccttagagc aaatcgaaga
    30781 tggacaagaa atcaatttca ccgatgatcg gaaagtccaa ttgatcaata atttacttgt
    30841 ctcaatcatt acagacaaag gaacgcaacc tgttatcaat acaggcgaca tgaaagaccg
    30901 taagtgacat actttttgta agataggaag aaggagttta ggacggatta ttgtcttgaa
    30961 ctcttttttt agttgtttta aagaaaatga caaaattgaa agaagaatga tagttgattc
    31021 gaaggcagaa ttgttcgctt ttttctataa tcagtatata aagtaagaga gaaggggaaa
    31081 aagtgaaaaa acttctgatc ggtctacttg ttttcatcgt tgtggtactt gcaggggtga
    31141 aaatcgcaga ttacgtagtt atgggtggag aagaatacta tgtacaaatt acgacagatg
    31201 gtacaaaaac agtttcaaaa tcagactctg gacaagaaac agtcaactat agatatatcc
    31261 tgcctggcta tacgaaagag ggtaaggaaa aagaactgga cttcaaggga caattgactc
    31321 gaccgcttcg taaaggagca tatttaaaaa tcacctggaa caaaaataaa ggtgtcactt
    31381 cgtatgaaga agtcgaaaaa aaagacgttc cgaaaacagc actggaaaaa ctaattaaag
    31441 ggtagggaaa gaaatgaaca aaatagtcga agtacagaat gtaacaaaag tatacggaaa
    31501 aaacaatgag aaaaagacgc aagcattaag cggcatcagc ttcgatgtag aaaaaggcga
    31561 atttattggg atcatgggcg cttctggttc tggtaaatcg acacttttga atattttatc
    31621 cacattagat aaaccaacag atgggcatat ccgaatcaat caaaaagatg tgaccacatt
    31681 aaaaggaaat caactagcag attttcgtgc gaatgagatt ggctttattt tccaagactt
    31741 caatttatta gaaagcttga cagcacaaga aaatatcgct gttcctcttt ctttacaagg
    31801 cgtcaaacca aaagaaatca agcaacgtgt ccaaaaaatt gcagaacgtt tatccatctc
    31861 tcatattttg gaaagctatc cttctgagat ttctggtgga caaaaacaac gggtcgccgc
    31921 cgcacgtgca ttgatcacac aaccaacgat tctattaggg gatgagccta caggtgcgct
    31981 ggattccaaa agtgcccggg atcttttaga tacgatggac gaattgaata caaaagatca
    32041 tgtatcgatt cttcttgtga cgcatgatcc gttttctgca agttattgcc aacgtatttt
    32101 attcatcaag gatggcggta tccatcaaga agtgaaacgt ggagatcaaa gccgtgattc
    32161 cttctatcga gaaatactat ctattcttgg aaacttggaa cagtaggggg agattgacta
    32221 tgctttggaa attatcactt actgggatca agagccgttt aagagactac ctggtgttat
    32281 tctcaggatt agttatggca tctgctattt tttacatgtt tgaatcaatg gcaagcaacg
    32341 aagctttttt gaaaagtaat acgatcgttg cggctacagt tatcattttc cgattcggtt
    32401 ctgttttact agggatcatc acattcgttt atattttata tgcaaattcc tttttgatga
    32461 cgatgcggca aaaagactat gcaatgttta tgatgctagg agcaaaaggc agaaaaatcg
    32521 cacagatgat tttttctgaa acattcttag tagggatcgc agctacttta gtgggttcag
    32581 ctgtcggtgt aggattgaca agtatcgtcc accgattatt agtggatcag ttagatctca
    32641 atatttcgca ttttacacct tttagtattc acgggttgtt gatcactgtt ttgttttttg
    32701 ctgttttgtt tttattagct gctgttgtca atgctttttc gattgtcaaa aaaccgatat
    32761 tagcattgat tcgtgcggat cagacaccaa caagaatcaa gcagcataaa ttcttgtttt
    32821 tccttgaagt agtactggga attgcttttc taggctgcgg ttactatatg atgaaacacg
    32881 tggggaccta tcaagtcttt ggtataggag tagccttagt tacgatcgta ttaggaactt
    32941 atttcatttt ccattctgtg atcattttct ttttatcatt actaaagaaa tcagaacaga
    33001 tttcattgaa aaaattgaac aatttcacat tgtcacagtt aaactttcgt attcgtgaat
    33061 atacacaaat gctctcaatg gtcgctatgc tgtttgcctt ggcactgggc gctttgacgg
    33121 taggattagg ttttaaaaat gaaattgcag acttgacaga aaacaattct ggatatgatc
    33181 tagtgatgaa taatcctcgg gcagaagatc agcaaaaaat caaagaactt tcaccaacac
    33241 tttctgcttc ttatactcaa aaagaagatg cgggaacgat ttactataat gcaagtgaat
    33301 ttgcggctca accattgatc atgataaaac atgaagatgg aacaccgccg aagatcacga
    33361 aagaaaaagt tcctgctgaa aaaatgaatg aactgactgt acaagaggaa cttcgaagct
    33421 atgaattgcc ggaacagcaa gaaaaagaaa tcaaggtagt cagtcaatca gaatttgatc
    33481 aactgaactt gccacaatcc actttacagc tagttcaggt aaaagacttc caagcaaacc
    33541 tgaaaccaat cgaaacactt gttgctcaaa ataaaatgaa caatccatct ttgcaaaaag
    33601 tagagtacag caaccagaaa tatgaaatgt atgaagtgta taatggtcta ttctctggtt
    33661 ttgaatttat gggattcttc ctaggtttag ctttcttgac catgcttgct agctgtttga
    33721 tgttcaagat cttgtcagga agcaagagtg acattgctcg ttatgaaatg cttgaaaaga
    33781 taggaacacg acgcgggttg cttaaacaat cgatccgtag agaagtaggc gtgttattct
    33841 tagcaccagg aatcttaggt gtagtccatg tcttattcgg attacaaatg tttggtctat
    33901 tcatgcaaaa tccatacaaa gatatttggg ttccgtttac gatcttcttc gtattgtatt
    33961 tcatctacta tgtactgacg acatggttat atactggaat cgtattgaaa aagagattgt
    34021 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagct cctcctattt
    34081 ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt gttcggaaaa
    34141 agaggttgtg acaatatttt tgtcacaacc tttttttcac ggtcttttat tagaatatag
    34201 taaatttttt ctcgttactc acggaataag ctgttaagaa aacggtttcc atgtatactg
    34261 gaatcagtgc aaatgaaaga aaagagggtg caaggaacat ggaaatcaat gaacaaaatt
    34321 ttggcgaaaa ctatcacttg attacgatca cgaatcaaaa tgggacatct ttgtctgtca
    34381 gtgatcttgg ggcacgggtt gttcattttc aaacaataat cgataatgaa aaacgagagt
    34441 tgatcttagg ttttgatgaa gcaaaagaat atctagaaaa agacccttat atcggtgctt
    34501 caatcggacg tatggctgga cggattacga atggcacatt caaattagat gatgaaacgt
    34561 tcgaagtaaa aacagacccg gacactggtc attgtttaca tggtggtgca cctagctttg
    34621 aagccaagca gtggcattat acagtcatca atggtgaaaa cgaagcatcg gtcattttct
    34681 atcagactag cccagacatg gaaaacggat ttcctggaac tttagatgta gaagtacggt
    34741 atacgctgac gaacgatgat acatggcgag tgacggtcca agggatcagt gaccgcaaaa
    34801 cagtattcaa tcctacaaat catgtctatt tcaatttaac cggtgatcca gcacagtcaa
    34861 tcgacgaaca tatactttgg ttgaatagcc gattatttgc tacgctcaat aaagatacaa
    34921 cgcctacagg agaagtagtt tcagtaagtg gcacagcatt tgacttccaa cgtcctaaaa
    34981 aattaggtga ggtctttgcc agtgattttc gccaatcaat gatagtgggc ggtatcgatc
    35041 atccattttt gttgaaaaaa caatctggtt tactaaatgc tgcggaattg acaagcccag
    35101 atgaaaaagt atcgatccaa gtaaaaacag atgcttcagg aatcgtgatt tttacagcaa
    35161 attttggaga agatggaccg gaaatgcgcg ggaataaatt agtaaatcat ggcggtatca
    35221 catttgagac tcaagaactg ccaggagcgg agcgacttga aagttttgga gatgtcactc
    35281 tggaacctaa ccaagtacgc gagtttgtaa cggaatacaa aataaatata aagaaataga
    35341 ataaattaaa aagggagtgt gacagtgtca catccccttt ttaatttatt ctatttcttt
    35401 aaaggcagat caagccagaa tgatttgtct aaacttaaca aggttagtac aggaacagtt
    35461 gcagctttaa ctgtacgagt agttgtttct ggtatctgtc ttgccgtaaa attgttccac
    35521 aaatcccaga ttgaagcgac acggaagatg gaagaagcgt tgttgacgcg ttttatcgtt
    35581 gaaaattcta atcctgtgat tggcacgcca tctgttgtcc atttgattgg cacatcgaat
    35641 cgcttagaca tattgaggat ttcagcgttt gcttcttcag ttgttgctgc ttcttttttc
    35701 ggttcatcat attttgtcag gtcgtacgct tcgatgatcg cgttcaattt ttgtgaatat
    35761 tggcgatctg tagcataacg tccttccaaa tatttggttg cttctttgta gtcttttgtt
    35821 tccgacttcc aagttggttt gtagaaatca ggattgccag tcagtccatt tttgatcaag
    35881 tcggcatagt cttccaaact ttccttgtaa gaaggatatt tacggaattg tgcgcggatt
    35941 tggtagcttt gtccggaact atcttgttca agtgtattga aggtcacgct gcttccttta
    36001 tatgatcctt tgataccaaa aaggttatga tttggttcgc ttgataataa gctgtttcca
    36061 gatccacttt caaggatagc ttgagccatc atgactgatg cgtagattcc ttctttttgc
    36121 ccgatttcct gtgcatcatc tgcaatcttt ttcaagaact gatcagttgt ttggttttga
    36181 ctgaaatgga acgagccatc taatccatct aaaatagatg agccgcctgt cagcgaacct
    36241 gaagcagcag gtaaacctgc taagtttact cggacagcaa aatcaggcgt gaaatctgaa
    36301 atagaagtta ctcgaacttt atctcctggt tgaggcgcat ggataaattg tccgttccca
    36361 atatagatac ctacgtggtg ggtaacacca gaagaaggtc cccagaagac gagatcacca
    36421 ggttgggcct gacttactgg aatctgtgta cctgcatatt gctgttcgcc tgtccagcca
    36481 ccgatataat gaccggttgc tttcatatat acgtaataag tcaaaccaga acagtcaaaa
    36541 gtatttggac cttttgctcc ccatacatat ggttttccaa gatgcttgaa tgcttctcga
    36601 acgattgctt gttggacatt cgttgtattt gtaggcaata cagcatcaat tggtgatttt
    36661 acaacaaaat cagaagaagc agaagatgga ttctctatac cgctttgatt tgctgtattt
    36721 ggacgagatg aagcattgtt cgttccgcca tttgatgaac cattgtttgg atggtttggt
    36781 tctctctgag tatttccatt gttattcgat ccagatgggt ttgtttgatt cgaagaattc
    36841 ccgctgttcg aattattgtt attattgttt gaattatttg aaccattatt attgttgtta
    36901 ttacccacat ctggtttgtt tggcgtttcc ggatctggtg tactagggac ttcttcacta
    36961 ggatcagttg gtttctctgt tgaagtatcc ggtacaggtt caaattctgc agtaatagat
    37021 aaattgttcg tacctactgt aaaggtcttt gcatcataat ttacttcttt ggcaccatta
    37081 acagcgactg aagcaatttg ttcaccttca gctggcgtaa tagtgtaagt taccttcgtt
    37141 tccgctaata aaccttctac cgttccactt tccgtaatat ccaaaggttg ctgttcaggg
    37201 gaatccgctg tcgaagcagt cagttggatc ttaccaatca aagaaggagc aattgtaagg
    37261 gaatatgtct cggctggctt ttcattttct gatggatcag ccggatcaat ttcagttggc
    37321 tcggtcgatc ctgttgttga gttagttgtt ccagttgggt cttctgtaaa agaatccgtt
    37381 gtttcactag tagctgagct ggatgtagtc gtatctgttg tgactgtttg atcagctgtt
    37441 tgattatcta cggcaaatac ggtattggtc gacaaaacag acggagcaat cagccaagta
    37501 gcagctagca aacgtatcgt ttttttattt ttcataataa actagtcctt ttcctttcat
    37561 tgattttctg tcttattcag cattcattag acattttttg gaacagataa tcgtgtcgaa
    37621 aagctttttc ttttcataaa tctgtctgtg tattctaaat aaaacaattt gtaaataagc
    37681 aacgagcatt cattcgtttt tcattgacgt tcattttatt gcatagacca cctttgtttg
    37741 gggataaaca agtggggata aaaatggtta tgcatatgta aattatacca aagtttggaa
    37801 agtatcacaa aaatttataa aaataatgat cctaaaaaga aaaagactga aatatgtgat
    37861 aaacatctca tacttcagtc tttttcatta actattcata agacattagg tcttcatcaa
    37921 acccgctaac gagagtagta atcattgcta cgactagact aacagccagt cctgctaagt
    37981 accagaaaaa agtaccggaa atgaatgcag gcaatgtggt cagactacca aatacaaaag
    38041 cgatcgcttt cacttgggca aatcccatta cagctccacc agcagctgca ccaatgcaag
    38101 cagcaacaaa tggttttttc aatgggatcg caattccgta aacagttggt tcggtcactc
    38161 ccgcaagtaa aatcgaagca aaagcagaac cggagatcga acgagttttt gaacgtttac
    38221 ttcgtagaaa tacacctaaa gctgcaccag ccattccaaa attggctgct cctgtcaacg
    38281 gaacgattcg gtcgaaccca taagcagaga tattactgat catgataggg tttacagccc
    38341 attggatacc aaatattacc aaaatattcc aaccaccagc gatgattgcg ccgctgatcg
    38401 gtccgttaat atccatcatc caagtaattg cggcagctaa accttcgcca aggtaaacac
    38461 ccgcaggccc gaataccatt aacgtcaaag gaaccgtgat aactaatgaa agtaaaggta
    38521 caaatactaa ttgcatattt tcgcgaatat attttttgag gaatttttca acaaaagaat
    38581 aaaagaaaat acctaaaatc gccggcatga cagtagacgt atactgcatc agtactacag
    38641 gaatccccag aaaatcagta gctgctttgc cactgtctga aagtaaagag gtcagattcg
    38701 gttcaatcag tgctgcagca atgacagccg caatatatcc attcacttta aacgttttgg
    38761 cggcagaaaa agcaagaaag attggcagaa aataaaagac ggcattcgac gcagcagaca
    38821 aaatatgata agttccgctt gtttcactaa gccagccaat cgtagtcgct aaaacaacca
    38881 gaccttttaa tataccagaa ccggcaaaca gcggaatgat cggcgtaaag atttccgata
    38941 tcaaaccaaa tagtttttcg atcggattta gcttttcttt aggagctgaa tgatcgattt
    39001 gacgcgttaa ttccttgtaa gcaggagcca atccctgatc catgattatt tctgcatatc
    39061 tatcgagtaa aatgaaatac ttaatggaag ggatttgctg ttttaatttt tctgcattgg
    39121 ctactggctg ttttttcaat ttgatacgaa gccgagtcgc acatggaagg acagaatcaa
    39181 tattgtcttt tcctcccaac tgttcaatca gcatatgaat ctgctcggac agtaccatct
    39241 gttcaggatt cattgtcgtt tccattagaa gaccactcca ctcactaata taatattggc
    39301 gtaaggtgtc atttcgcctg tacgaataaa tgcatgacag ttattcaact cttttttcat
    39361 ttcttcatgt gggataaagc taatcggtgt atctggtaac aataatttga ttttttccaa
    39421 tatttccggg ttcattgtct ttatttcttc cgccaattca atcgattgta cctcaagttc
    39481 ttctaaaacg ttttctaaaa cagataaaaa gcttggaaga ccgtttgaga cagccaaatc
    39541 tattttttca gtaccaaagg ggacaggcat gcctgcatcc ccgatactta atttatcaaa
    39601 gtgccccatt tgtgcgatta ctcgtgaaat atctgaattg attacttttc cttttttcat
    39661 gtttgtttct tcctctcatt gttaatttta gactgctgat tgttctaaag cttcgcggta
    39721 agggatagaa ggttgcgcac cataagactg cacagcaaca gaagaggcta gatttccata
    39781 aaggatcgct tctttcaagt tactaaggtc tggctgaagt gtgctgctta atgcgccaat
    39841 aaatgtatca cctgcggctg ttgtgtcaac ggcatccact ttaaaagcag ggacgatacc
    39901 gtgttctttt tctgtatgat agaaagcgcc ggcactgcct agtgtaatga ttactgttcc
    39961 aatacctaat tcatggagtt tttcggctgc tgcgaccaaa ctgttatgat ctgtcactct
    40021 gattcctgta atgatttctg tttctgtttc atttggtata atgatatctg ttttttcaag
    40081 tagttcagta gggatcgttt cacgagctgg tgcaggattc aggatcgttg tttttcctgc
    40141 gtcttttgca atagaaaaag ctaggatcgt cgcatctaag ctactttcaa actgagcaat
    40201 aataaagtca ctgtttgtaa tcagttgctt gttttttagg acttcttgtt catggaaagc
    40261 attatttgca cctgcatgga tcaagatact attttctcct gctgcgtcta ccataatcat
    40321 tgcttgtccg gttgtggcgc cttggatttc agctatccca gatgtatcga tgttttcttt
    40381 tgtcagtaga tctaataact gttgtccttc gctgtcagcc ccaacgcctc caataaaaga
    40441 tgtccgtgcg cctgaacgtt tggctgccac tgcttgattg gcacctttac ctccgccagc
    40501 gtgaaaaatc tcatgcgcat gcattgtttc gcctggcttg ggcatgttgg ttaaacgaag
    40561 ggtagtgtcc atattaatac ttccaattac tgtaaccgtg ttcattttac aaacctccaa
    40621 ctatctcatt tattttgatg ggaaaaatta ttttttaaaa cgttttagta aaacgtttta
    40681 atagttcgat aaaaatatag cacaccttga aagctatttc aagggtgcag ttgaaaatct
    40741 tttttctaat cgtacaggta atcttttttc ttcccattct ttttctggga attggatccg
    40801 atctaacaat aatttggcag atgtttgtcc caattcgaag atcggttgtg cgatcgttgt
    40861 cagtttcggc ttgatatact cgcacatatc tatattatca tagccaataa tgctgtagtc
    40921 ttcaggaatg ctttttccag attcctctaa tccgcgatat aatccaaaag ctaattcatc
    40981 atttaaagca aacacaccag ttgcagcaga atcaagaagt tctgctgtga tttggtagcc
    41041 accttgtttt gagaactgtg taggtaagag gatcagttgg tcgtgagaga tttggtaaac
    41101 atcaagagca gatttaaacc cctcaatccg agcgtggaca ttttccggcg gattttcagg
    41161 atagacaagg gcgatcgttt gatgacctag actaagcaag tgcatgcccg ctaggtaacc
    41221 accgcgaaaa tcgtctgttc gtacggcatc actaaatcct tcagattttt tctgatccaa
    41281 aacaatgaag ggccggcctt gttttttcaa attttcgttg attgcatctg tagagacagc
    41341 agaagtcgcg ataatgaatc catccacacc tcgacgtgtg agctcggcta gatattcgat
    41401 ttctttttga tgatcagaat cagcattaca taatatcgtg acgaaattct gcttatacaa
    41461 gatatcctca attcctcgca tcagtgtact gaagaatgga ttcgtgatat caggaacgag
    41521 tacaccaatt gttttcgttt ccttggtaat catttgtcta gcaaaatagt caggctgata
    41581 gcctaattct tctttggcag ctaaaacttt ctgaacagtt ttcggactga atttctccgt
    41641 atttccattt aatatcaagg agacagttgt gattgaaacg ccggaaagtt tagcgacttc
    41701 tttgattgtg atcttttttt tcaccatgtt catactccta tctaaatcct gtggttattt
    41761 tcccatgaaa tcaaaaagaa gtaaatgaaa atcacgtgtg ccagtactta tttgctttgt
    41821 tggatagctt cgattatttg tttcgttgag cgtactcgtg cagttttcgg aaatatcttt
    41881 tttatgaaca attgatggga ttctttgtca cgatcactgc aagcatcttc agcaagtaca
    41941 acatgatacc catgttggaa ggcatctaat gcagtagcat atacaccgtt tgttgtcgct
    42001 acaccgctta aaacgatagt ttcgattcca cgccggcgaa gttgaagatc aagagaagta
    42061 ccaaaaaagg cacttggatt gtattttgtg atagtcaaca tattgtttgt atctttcaag
    42121 gaatccttca acaacaagtc agtgaattct gccggagcag acaaagcaga tattcctcca
    42181 gcatctgtct gatgacttag ataagagaaa gtagtgatgt ctacattcac taaaactttc
    42241 aaggcagcgg tacgtttcaa tgtttttgct aacaaatcat tgtttgtcag aatagattgt
    42301 gcagtgtgtg gagagagtgt accgttattt acgatccctt tttgcatgtc gatcgcgaca
    42361 aaagcagttt ttgataaatc aaaaatcata ttttccttta aatcattcat gatgttcctt
    42421 ctttcaaata acaatgtttt ttatgtaagt aaatcataaa tcgtttattt gtcaactaaa
    42481 taaaggattc ctttctttag tctagagaaa ttcagtggta aaataaataa gtatgagaaa
    42541 acgcattcga tgcatagata tagcgagaaa tatcgtgaaa atggaggaat cagagtgaag
    42601 tatgtcgaag taaaaaatga atacaaacga tacaaaatgg gagaaacgac cattacagca
    42661 aatgacgata tttctttttc aattgaaaaa ggcgaattag tgattatact tggtccaagt
    42721 ggagcaggaa agtcaacgat tcttaatatt ttaggtggga tggatacacc tgatgaaggt
    42781 cagatcatta ttgatgacac agatattgcg caattttcag ataaacagct tactgcttac
    42841 cgacgaacag atgtagggtt cgttttccaa ttctacaatc tcgttcctaa tctaacagca
    42901 aaagaaaatg tggaattggc aacggaagtt tctcctgatg cgcttgatcc tgtagaggta
    42961 ttgaggcaag tgggcctagc tcatcgattg aataactttc cgtcccaatt atcaggaggc
    43021 gaacagcaga gggtttcaat tgctcgtgca ctagctaaaa atcccaaact tcttttatgt
    43081 gatgaaccga caggcgcgct ggattttgaa acgggcaagc aagtattgaa attattgcaa
    43141 aacgctagca gacaacacgg caataccgtt ttgatcatta cacataattc tgctttagcg
    43201 cccatcgctg atagagtcat tcacattaat gatgctaaag taaggtctgt tgaattaaat
    43261 gatcatcctt catccattga tgagattgta tggtaggggg attttatgaa aacaagaaca
    43321 tatcttaaag caggttttcg cgaaattcgg caatctaaag gacgattcat tgcaatcatc
    43381 cttattgtca tgctaggaac acttttattt gtaggtgtca aaactgctgg acctgtcatg
    43441 caaaaaacga tggaccacta tgttggtaca gcaggacttt ctgatttgca aatcgtttct
    43501 actggtggct tgacacaaaa agatattgct caagcagaaa agatcccaga tgcaaaagta
    43561 gaaacaggaa aacagatcta ttattccaat actggtaaaa acgaagtgat tcaaatattt
    43621 tcttataaca aaaataacaa gcagaacaag ctacaattaa ctgatggaaa actcccggaa
    43681 aaaccaaacc agcttgtatt ggatgaaaaa gcggaagatg aagggtataa agtcggtgat
    43741 atttatcaga ttgattcaga tgaattgaaa gaaaaagagt ataccatcac gggctttgtc
    43801 cgttctccat tgttcatcaa caatttggag agaggatacg cgaacgtcgg aaatggtagc
    43861 gtcgattatt ttgtctattt acctgaatcc gtttttaaaa cagatattta ttctgtctta
    43921 tatcttgatt ttacaaacgt aaagaatttg aatacgtaca gcaaagctta caaagataaa
    43981 atggaacaca atcaagagaa ggcagaaaag tatttacaag atcgccctga agaacgctta
    44041 gaagagctga aaaaatcggc aaacgaagaa ttagaaccag cacagcaaaa aataacagaa
    44101 ggcaaagcac aaatagcaca gggaagaaca cagttagaag atgctaaaaa acaattagcg
    44161 caacagtcag cagctatcca gcagcttcct gaagcgcaac gaacaatcgc tgttcaaaca
    44221 ttatctcaac aagaagctca acttgctgaa caagaaaggc aattagttga gaaagaacgt
    44281 gaactggcct ctgcagagga agaattgaat cgaaatgcag aaaaaattga aaatttaact
    44341 aaaccatcat acctatacaa tgaacgttca gaaaatgtcg gttttcaaga atttggtgat
    44401 ctgtctgatc gtatcgctgc gattgccaat gtttttcctg ttttcttttt ctttattgcc
    44461 gcattgatca cctttacgac aatgacacgt atggtagaag aaaaccgcag ggaaatcggg
    44521 acattaaagg cgttaggtta tacgaaagtt gaaatcgcaa aaaaatatgc aatctatgca
    44581 agtctagcct cagggatagg cattgtttta ggaacgatat taggaacgaa tcttttgcca
    44641 aggatcattt ttgagctgtc taacgagcgg tatgatattg ggagtgcgct tattttttat
    44701 gactggccgc cgattttaca agcagctgcc gcattcttca ttgccgcatt tggcgctgca
    44761 atgatcgttt tattcaaaga tttaagagaa cggcctgctg cattgcttca accgaaagca
    44821 ccgaagccag ggaaacgcat ttttcttgaa tacatcactc cgctgtggtc acgccttagc
    44881 tttaatcaaa aaatcagtta ccgaaatctc ttccgatata agtcaagaat gcttatggcg
    44941 attatcggaa ttgctggatg tgccgggctg atggttgcag gcgtgggatt gaaagattct
    45001 ctaagttctg tctcagctaa acaatttgga ccgatcattg actatcaagc aatcgttaca
    45061 ttggattcat ccacggaaga tagtcgtcaa aaagcagcgg atatgctgca gaagcaagaa
    45121 aaagtaaatg agatcctagc tattcatact caaaccgtag aattgagaaa aaaaggacat
    45181 gcttcgcaaa gtctgacagt gatcgtacca agtaaaacag ctgatttgga tcgttttatc
    45241 catttaactg atcttgaaga gaacccacgc tccttgccta aaacaggaat cgctattacg
    45301 caaaaagcag cagaactatt tgacttatct acaggagatc atatttcgct ttatgatgaa
    45361 gatcaaaaag aatggaaagt cgaagtaaaa gaaatcgtga aaaactatct aggtagcttt
    45421 atttatatgt cccctgaata ttatgcttca gttactgatc aatcgatgat ggataatgca
    45481 tttttgctgc gtacagataa gatgacaaca aaagaagaag aaatgctttc cgagaaactg
    45541 cttgccacag acgctgtgac aaatacgtct ttcatgtcca aacaaatcga aacgcaagaa
    45601 gaatcaatgg cgaacttaga ctcggttgtc ttaatctttg tcgtattatc aggactgctg
    45661 gcttttatcg tcttgtataa tctaactaat atcaatattt ccgagcgtgt acgcgaatta
    45721 tctacaataa aagtccttgg attttttgat aaagaagtca cgatgtacat tgttcgagaa
    45781 aatatcatct ttactctttt aggaatcatc ggaggatttg gtgtaggata tatattgact
    45841 gacttcatct tgcaacaagc gtctatggag aatgtcatct ttccattagt gatcacatgg
    45901 tggtcttatg tcttatcagc aggattaact atcgtattta cggttattgt gatgattgtt
    45961 acccatttca aattaaagca tatcgatatg attgatgcgt tgaaatcgaa tgaataaaaa
    46021 cagaggttgt gaaatcagcg ttttgagcta ataacgaggg tcagctgcta attgaacacc
    46081 gtgaatcaga ggttgtgaaa aagctgtcct gcatcgagca aaaggaatac tcaaataaaa
    46141 ttagctcctc atgttttaca tttgagaaga ctgattgccg tagataaaag cttttgagca
    46201 ccatttatag aagaaacaag aatattttgc tattttaaac aagaggatag acaaatacat
    46261 gtctgatctc ttgtttttta ttgggcaaca gacctcttag aatgtataaa gataaatttt
    46321 acaaacgctt tctgttcagt tataataata aatgataact tgtatatata agttgcggta
    46381 ggtaataaat cagttgaatg gaggtaaata tccatgacat ttaaagacaa agtcatttac
    46441 caaatctatc ccaaatctta caaagacagt aatggtgatg gaattggaga tttaaaagga
    46501 atcaaagaaa aactcccgta tctgaatgat ctaggcatcg acatgatttg gctaaaccct
    46561 atttatccaa gccctcaaaa agacaacggt tatgatatct ctgattacac agccatcgat
    46621 cctatctttg gtacgatgga ggaattcgaa cagctaatag ccgaagcaaa gaaataccgg
    46681 atagaaatca tgctcgatat ggtgctgaat cacgtttcga cagaacatga atggttcaaa
    46741 aaagcactag caggggacca gcattatcag gacttcttca ttttaagaga agagccaacg
    46801 gattgggtat caaaatttgg tggaagtgct tggtcgccat ttggagatac ggggaaatat
    46861 tatttgcact tatatgatcg gacacaagct gacttgaact ggcggaacca agcagtaaga
    46921 gaggaactat tcaaagttgt tcgtttttgg atggaaaaag gggtaaaagg attccgtttc
    46981 gatgttatca atgttatcgg taaagacgaa caattgaaaa ataacaaaga aaatgatggc
    47041 aaacctgaat atacggacaa accaatcacc catacgtatc taaaagaatt gaaccaagca
    47101 acgtttggga cggattccac tatcatcaca gtcggtgaaa tgagctctac gacgatcgaa
    47161 aattgtatct tgtatacaga acctagtaga gaagaattat caatggtctt taatttccat
    47221 catttgaaag tcgattatga aaatgggaat aaatggtcta ctcctccatt tgattttgca
    47281 gaattaaagc gactatttca tacatgggga gaaaagatga gtgagggtaa cggctggaat
    47341 gctctatttt ttaataatca tgatcagcca cgtgcgctca atcgatttgt agctatcgat
    47401 cagtatcgaa aacaaggagc agagatgcta gcaaccatga tccatttgaa ccgtgggacg
    47461 ccctatattt atatgggaga agaaatcggc atgatcgacc cagactattc atcgatttcc
    47521 gactatattg acgtagaaag tttgaatgct tataagttac tccttgaaca aggattcaca
    47581 gaaaaagaag cgtttcgtcg gatcaaagca aaatctcgcg ataactctcg aacacccatg
    47641 caatggtcag acacagaaca agcaggattt actacaggga aaccttggtt aaaagttgga
    47701 ggcaagctag aagagattaa tgtagaaaaa gaactatctt ctgaagattc tattttgtcc
    47761 tattacaaga aattgattcg gctgagaaaa acatatccaa tcgttgcaca aggagattat
    47821 catgcttatg aagcaaatca tccggaagtt tatggctttc ttcgccaatt tgaaggacag
    47881 cagctgcttg tattaacaaa tttctatgat aaagatacaa ggatcaccat cccagaagga
    47941 ttcacagaag ccaatattct tatcgataat tattccgata ctgttcttca tcaaagtctg
    48001 gagctaaaac cataccaggc aattgctttg ctgaaaaatt aaaacaaaaa cacaaaacgt
    48061 cgttcctacg agctattctc gtaagatcga cgttttgtgt tttatttaaa ataatcttct
    48121 tcagaaaatg aagagttttc atactctcct ttatcgccat aaaatttatt gtagcgttgt
    48181 ttgaatttac ggaaaataaa agtaacgagt aatttgacta acgtatagat aggaatacca
    48241 aaaataacgc ccacaattcc cattagatca cccatgacaa gtaaaacgat taagatcgta
    48301 atcggatgga tctgtaaacg atcacccatt actcgaggaa tcaccaagtc accgtggaga
    48361 agttgtacgg caaaccagac aatgacaaat ttgacagcca taaaagtaga gtcttggaat
    48421 gcaatgatca aacctggaaa gaaggcgata aacggcccaa tatatggaat gatacataac
    48481 aacccagcag aaatagctaa aacactagca aattctaatc cgatcagtaa gaaacaaacc
    48541 cagtagactg ctccaaggat aaatgaagca atgatttgcc cctttagaaa tgaacccaat
    48601 tgttgattag caatctttgt caaattttta aaatctgtac gaaatgctgg tgggacaatc
    48661 gctaaaactg actgataaaa tttttgagga tctctcaaaa gaaaaaaagc gacaattgga
    48721 ccagtaaata aagtaataaa aatagctgta acagttgaaa aaatgttgct gatccgttgt
    48781 gcgccacttt cccaataatt tccaataaat ccagctatat cagacgtcac gtcgtcaata
    48841 gaagcgaaaa attgattaaa tgaatcggca aaaggtgttt tctctaaaaa ttgtcggaga
    48901 ctctcttgaa aatcttgaaa caaatctggc aaactactga tcaatgtctt tgcctgttct
    48961 tcaagaaaag gaacaagcca tacgcttcca agccccaata aaaataaaat aatcacataa
    49021 acgataatga ctgacaagtt cctcgaaagg tgcttgctca aacgtttgat gactggttcc
    49081 aaaagataat acaagatcag tgcaaacaat aatgggggca agatagtagc gataatgatt
    49141 ccgacaggct tgaatataaa cgagatctga tggaaaaaat aaatgatcag cgcaagtaag
    49201 ataactattc ctaaaacata gtaagaggtt tttcctccta aaaagcggat caaacgattc
    49261 gttgtatctg tttctttttt cactcttttt cctcctttat ctataacttc attatagaca
    49321 aaagcgggta taaaaggaaa atgatagagg ttgattgcaa aaatatcgtc aatcattcat
    49381 ataaactttc tcatcaatta aaataagaaa acgcttgaca gttcttttaa ccatatgata
    49441 aattaaatcc tgttgctaaa acgtaactat tacgttttgt aaaaggcgaa tcggaacatt
    49501 caaatgaaag aagatgagaa gaggagtgtc ataaatgaaa cgattgatag gtatattggc
    49561 catgctggtt ttagcaggta tgttaactgc ttgcggcggg gcaagtggga aagccgagga
    49621 cagtaaagaa aaattgagcg tgatgacgac cttttatcct atgtatgatt ttacaaaagc
    49681 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    49741 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    49801 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    49861 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    49921 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    49981 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    50041 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    50101 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    50161 acatgctgca ttcaactatc tggcattaga atatggattg aatcaagtat cgattgctgg
    50221 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    50281 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    50341 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    50401 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    50461 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    50521 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    50581 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    50641 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    50701 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    50761 gtttaaggat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    50821 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    50881 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    50941 tcatttatat gcaggaaatg aaagtcaaga agcattgctg aaagaaatgg agaattggcc
    51001 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    51061 ataggcaaaa aagaaccgaa gggtttggat cggctagtca tttagtcggt ccaaactatt
    51121 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    51181 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    51241 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    51301 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gtgctcctag
    51361 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    51421 tattttgaag atatcttttt ggatctggga catttgaaaa tcttcgaaaa ttttgctcag
    51481 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    51541 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    51601 ttttcctaag ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    51661 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    51721 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    51781 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    51841 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    51901 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    51961 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    52021 ttgtttcaac tggtttaacg gcaatgtatt tgttgttgta ttgatcacac gaatcatcac
    52081 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    52141 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    52201 atccagttcg attggctcag gaaaatgaag ctggacgacc aacccttttt cctgtgccat
    52261 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    52321 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gagcataata
    52381 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    52441 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    52501 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    52561 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    52621 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    52681 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    52741 ccaagtctct aacgattttt taaaacaaaa agctaataaa gcagataaaa aagcggataa
    52801 ggcaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    52861 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    52921 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    52981 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    53041 agaagtcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    53101 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    53161 ctcccattga tttttaccaa attatagcac aattagcgta ttattttttt aatttttcag
    53221 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    53281 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    53341 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    53401 aagtaagaag ctgagaaaaa taaagtaatg agagaaaaaa ttagaaacat gctgatcgcc
    53461 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    53521 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    53581 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    53641 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcatata
    53701 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaaa
    53761 acgaccgcta gttttccaag attattcaat aaaacttcta aggcaaattt tacttggaca
    53821 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    53881 actttatctt tcatctcata cgtacctcta ccacaaattt tatgctaaaa aaaataaaaa
    53941 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatt tcctaaaaaa
    54001 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    54061 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaaattactg accttataaa
    54121 aggtgatgga gggattctta tggaaaatga acaattgttt gaagtcggcg aaacatatgc
    54181 atttaaatct gatttatttg aatcaccaat aaaaggaaaa atagaaaaaa tctatgaaaa
    54241 tagtgtgatg atacgtgtca tgaaatgcgc agtagaagac aatgataccg ctcataatct
    54301 gcactggcag ttagttgtac gcaaatcaag tacaatagaa gaataaaaac agataaaatg
    54361 ttgagagcat aaagaggttg tgagtctccg tttagctctg agttacaagg aataatgtta
    54421 aaaaacagct tttcatgttt tatgaatatt gccacttgtg accgaggtgt tggcaggaga
    54481 atactgttta tttgaaaaaa gggctgcgac aagacttttg tcacagcctt tattttcatg
    54541 aataggagtt acttttggct acttttagag aagtagcttt taaggagcag ataaagtcaa
    54601 ggcttttatt tctataaatg aagtagtaaa atgaagaaca gattttatta caggaaggat
    54661 gccgataatt gtgatcattg ttgcaggaac gatcggtgca gggaaaagca cactgactga
    54721 aatgcttgcc caagatttag aaacaaaacc tttttatgag aacgtggaag ataatgaagt
    54781 attgccgcta ttttattcta atccagaaaa gtatactttt ttattacaga ttttcttttt
    54841 gaacaaacgc tttttggcaa tcaaagatgc tttcagccat gatgacaatg tactagaccg
    54901 ctccatctac gaagatagta tgctgtttca tttgaatgca gatttagggc gtgtttctga
    54961 agtagaagta aagcagtatg aaggtctttt agaaacgatg ctgaaggagt tagaagaaat
    55021 ttcgccacaa aagaaaccag atctactggt ttatattcgt gtatcttttg aaactatgtt
    55081 agcgagaatc aaaaaaagag gccgggaata tgaacagcta gaacaagatc ctgaactcta
    55141 ttcctactat aaagaactca atcgacgata cgaagagtgg tatgaacagt ttgatatatg
    55201 tcccaaaata gtgatcgatg gggacaaata tgatttcgta gccgatccgg catgtggaga
    55261 acaaatcgta caagaaatca agatgcgggc aaagaaaatg acagaagagg cagatgccca
    55321 gtcgatccgc tacactacaa ataacccgaa agcaaaggga atctttacaa ctaaataata
    55381 taaaaactaa gcaaattgct cactcgcaga tatttctctg tgagcagcat cttgcttagt
    55441 ttttttgatt cattgagatc aaatagtgaa ccgattcgta tgataaaatt gccataaatg
    55501 aaatgtctga gtgagggcca tgatcaaaaa taaaatggaa acgatcaaaa tcgaatgggc
    55561 gccaaacaga tgatgacaga aaacaaggac aatagctcct gcgataaagg caagaacgac
    55621 acttagatag tggaaaaatc gatcaaaatc tgctttttct ttagaaatac aataatcata
    55681 taagttcgtt gctacccctt ttaaatttcc agttgtaaat aaattagtgt aggcacgccc
    55741 gttgatttta tcaaaagcta cccactggat cgatgcagta aaagcaatca aaatcgttac
    55801 taatgcggga tgctcatgga cgggtgtcaa actaacaaag aaaaaaatca ctgcttcata
    55861 atatagaaca aacaagcgcc agaaatgttt ttcttttttt ctaaaataat caattagata
    55921 ctttgttaga agaatcccta agaaaaagaa aagggtagac aatacttttt taccaacact
    55981 tagccattct ccgtcaaatg cttggatgat cgatagaatg atattgccag tttgagcaga
    56041 ggcaaaagca ccatattgga tataagtata actgtccatg gctcctccga taaatgtcag
    56101 caaaagtcct attgtacgcc cctcgtgaaa ggaagtctgc atttttttca tcacctttta
    56161 tgaatatttt tgtcttcctt atcttagcat aaacgattga aaaaaaggaa aaattttcag
    56221 aaaactaaaa tcatatcgct tcccattttc atttttagaa aggtctgtta gtataaagaa
    56281 aaaatagaca acgaaacttt aaataaccaa cttgaaataa ccaacttgaa ataaacaaat
    56341 tcaaagaaga aagatgggaa ggaaatcaat cagttgaatg aaaaagaaat tctccgatta
    56401 caaaaagaat tgaaacgctg ggagaacaag tataaaaagc ttcaacaagt ctttcggcta
    56461 caagaagaaa tcattgctac ctatgaagcg gcttatggcg aagcacccgg acttattgag
    56521 gaagaagtac aagtaaaaga aagtgaagga aacagctctt tctttaaaat gatggagaaa
    56581 cgttcctata atcgcttcaa tcaagaacaa aaagcagcta tcacatatga tatgaagaaa
    56641 catcttcgaa tcatagcagg agctgggagc ggcaaaacgc aaacaatctg tgcaaaagct
    56701 gtttatctga tgacgcaaaa acaagtagac gaagaacgca tactaatgat cacttttaca
    56761 aggaacgctg caaatgaact aaaaaaacga gtagataatt tcagccagag aaaaaccgct
    56821 gtccatatcg gaacattcca tagtatcttt tttaggatat acaatgaaat ttgtcgaaaa
    56881 tttcctgaag tagcaatgca aggaatacaa ggagactttt caaaggatac tgcacaaaaa
    56941 gtgaatgctg ttttgcaaca gctgatacgt aaatataatc tttatatatt tgatcaatat
    57001 ggagaaaaaa cgattgcttc tcggttagac tattggcaga atatgaacct ttcagtagaa
    57061 gaaatggttc agttagttaa agaaaaatat gattccattg ataagaatgc acgacagccg
    57121 atatcagaac gactgtatgg attgctcacg gaactccaag aacaaaaaag aagccagcaa
    57181 ttgctagagt tcaatgatgt actccaaaat ctgaaaagcg ctttggagaa tgaggagatc
    57241 cagcattata tcggccaaaa atatgattat ctattcattg atgaatttca agatactaat
    57301 ccacttcaat gggaaatcgt gaaacggatg acaaaggaaa acaggatcaa gttgattgtt
    57361 gttggagatg atgatcagag tatctatgga ttcagaggat cagagccagc atacatcaag
    57421 aactttgaaa aagaatatcc taccaaaact cttttcttat taactaatta tcgttctcgg
    57481 gcagctattg tccaaggagc aaatagattg atcagctata ataaaaatga tcggatacca
    57541 aaggcgatga ttccagcaca aaaagaagca ggtgttatgg aagcctattt gttttctgat
    57601 actaaagcag aaagtcagtg gctaatcaaa caaattcaga catttattca aaaaaatggg
    57661 aaatataagg aatcaatcat attataccga tcagcttcac aaacgcagca gcttgtccaa
    57721 tctctgctga aaacgaatat tccttttgta ctggaagcag atagtccata tgaaggtatc
    57781 tttggtatca agtctttcca acatttctat caaaaaattg ttcattggca aacagcactg
    57841 aatctgcaaa agaaaaatca ggcctaccag caattgctcc ggcagctgat ggcagactgc
    57901 tacctgaaaa aaagtgaatg cgatcaatac ttttctccta aatatcaaaa tatagccgtt
    57961 gcagattata ttttgtcgat aagccccaat ttaaaatcaa aatctgcaga aatccgagag
    58021 tttgaggaag cgttgcgtaa aacagaccag catcaagaaa tctattcgct tgttcaaagc
    58081 tatcttcatc tgccacgtat agctaaggaa atcgaccaga gtgatcaaga atggatacga
    58141 gaagaagtaa agcagcatgc tactttcaga agactccaag ccttatcgca agaaacccaa
    58201 gcgacagcta aagaattaaa aacccgcttg attgcttaca gacaaggaaa acttgatgca
    58261 ctatgtatcc agagcattca caaaagtaaa ggtcttagtt accgaaatgt ctttttgatt
    58321 ggttgtaacg aaggaagttt gccttataac ggagcgacag aaaagaaagt aatcgacttt
    58381 aatgaaataa aagcagaacc agtgacgacg atagaagaag aacgaagact attttatgtt
    58441 gcgatgacta gagcaagaaa tcgtctgtat ctatgtgtac ctcaaatgaa aaattcaaga
    58501 aaattgaaag tatcgagatt tatcaaagaa accgggagtc gtgtgaaaaa aggaaagtga
    58561 tagaagagag ggtgtgacag aagtggtcag tttcaagaaa gaagaaggaa tgtacgaaaa
    58621 ttgcttctca aatttttgtg aaatttcagc ttattttcga agaagctatt tctggaacac
    58681 cgtttattcg gaaaaaggag gtgtgacaag aattttgtca cacctccctt atttattttg
    58741 aaaatgagaa tactattatc aaaatagaga atatatagaa taattctcat tattcaaacg
    58801 taaataatca gtt
//
LOCUS       DAPBBR010000012        57642 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPBBR010000012 DAPBBR010000000
VERSION     DAPBBR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 57642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.012"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..131
                     /locus_tag="RD488_000750"
     CDS             <1..131
                     /locus_tag="RD488_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7656847.1"
                     /translation="QVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLT"
     gene            complement(187..2550)
                     /locus_tag="RD488_000751"
     CDS             complement(187..2550)
                     /locus_tag="RD488_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HDT7656848.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2998..3219
                     /locus_tag="RD488_000752"
     CDS             2998..3219
                     /locus_tag="RD488_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7656849.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3327..3674)
                     /gene="rbfA"
                     /locus_tag="RD488_000753"
     CDS             complement(3327..3674)
                     /gene="rbfA"
                     /locus_tag="RD488_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDT7656850.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3701..6007)
                     /gene="infB"
                     /locus_tag="RD488_000754"
     CDS             complement(3701..6007)
                     /gene="infB"
                     /locus_tag="RD488_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDT7656851.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(6020..6331)
                     /locus_tag="RD488_000755"
     CDS             complement(6020..6331)
                     /locus_tag="RD488_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HDT7656852.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6328..6621)
                     /locus_tag="RD488_000756"
     CDS             complement(6328..6621)
                     /locus_tag="RD488_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDT7656853.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6643..7818)
                     /gene="nusA"
                     /locus_tag="RD488_000757"
     CDS             complement(6643..7818)
                     /gene="nusA"
                     /locus_tag="RD488_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDT7656854.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7842..8315)
                     /gene="rimP"
                     /locus_tag="RD488_000758"
     CDS             complement(7842..8315)
                     /gene="rimP"
                     /locus_tag="RD488_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDT7656855.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8459..12811)
                     /locus_tag="RD488_000759"
     CDS             complement(8459..12811)
                     /locus_tag="RD488_000759"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDT7656856.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(13023..14732)
                     /locus_tag="RD488_000760"
     CDS             complement(13023..14732)
                     /locus_tag="RD488_000760"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDT7656857.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14800..16068)
                     /gene="rseP"
                     /locus_tag="RD488_000761"
     CDS             complement(14800..16068)
                     /gene="rseP"
                     /locus_tag="RD488_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDT7656858.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16229..17029)
                     /locus_tag="RD488_000762"
     CDS             complement(16229..17029)
                     /locus_tag="RD488_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDT7656859.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(17026..17838)
                     /locus_tag="RD488_000763"
     CDS             complement(17026..17838)
                     /locus_tag="RD488_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDT7656860.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(18033..18590)
                     /gene="frr"
                     /locus_tag="RD488_000764"
     CDS             complement(18033..18590)
                     /gene="frr"
                     /locus_tag="RD488_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDT7656861.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18593..19315)
                     /locus_tag="RD488_000765"
     CDS             complement(18593..19315)
                     /locus_tag="RD488_000765"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDT7656862.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19451..20332)
                     /locus_tag="RD488_000766"
     CDS             complement(19451..20332)
                     /locus_tag="RD488_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDT7656863.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20431..21213)
                     /gene="rpsB"
                     /locus_tag="RD488_000767"
     CDS             complement(20431..21213)
                     /gene="rpsB"
                     /locus_tag="RD488_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDT7656864.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21572..22051
                     /locus_tag="RD488_000768"
     CDS             21572..22051
                     /locus_tag="RD488_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HDT7656865.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22268..23359
                     /gene="phnW"
                     /locus_tag="RD488_000769"
     CDS             22268..23359
                     /gene="phnW"
                     /locus_tag="RD488_000769"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDT7656866.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23352..24137
                     /locus_tag="RD488_000770"
     CDS             23352..24137
                     /locus_tag="RD488_000770"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDT7656867.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24483..26174)
                     /locus_tag="RD488_000771"
     CDS             complement(24483..26174)
                     /locus_tag="RD488_000771"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDT7656868.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26596..27543)
                     /gene="arcC"
                     /locus_tag="RD488_000772"
     CDS             complement(26596..27543)
                     /gene="arcC"
                     /locus_tag="RD488_000772"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDT7656869.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27658..28677)
                     /gene="argF"
                     /locus_tag="RD488_000773"
     CDS             complement(27658..28677)
                     /gene="argF"
                     /locus_tag="RD488_000773"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDT7656870.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28768..29997)
                     /gene="arcA"
                     /locus_tag="RD488_000774"
     CDS             complement(28768..29997)
                     /gene="arcA"
                     /locus_tag="RD488_000774"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDT7656871.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30458..31159
                     /locus_tag="RD488_000775"
     CDS             30458..31159
                     /locus_tag="RD488_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7656872.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31731..32747)
                     /gene="tsaD"
                     /locus_tag="RD488_000776"
     CDS             complement(31731..32747)
                     /gene="tsaD"
                     /locus_tag="RD488_000776"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDT7656873.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32744..33208)
                     /gene="rimI"
                     /locus_tag="RD488_000777"
     CDS             complement(32744..33208)
                     /gene="rimI"
                     /locus_tag="RD488_000777"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7656874.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33215..33757)
                     /gene="rimI"
                     /locus_tag="RD488_000778"
     CDS             complement(33215..33757)
                     /gene="rimI"
                     /locus_tag="RD488_000778"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7656875.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33741..34463)
                     /gene="tsaB"
                     /locus_tag="RD488_000779"
     CDS             complement(33741..34463)
                     /gene="tsaB"
                     /locus_tag="RD488_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDT7656876.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34654..35634)
                     /locus_tag="RD488_000780"
     CDS             complement(34654..35634)
                     /locus_tag="RD488_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7656877.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35658..37142)
                     /gene="galT"
                     /locus_tag="RD488_000781"
     CDS             complement(35658..37142)
                     /gene="galT"
                     /locus_tag="RD488_000781"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HDT7656878.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37154..38143)
                     /gene="galE"
                     /locus_tag="RD488_000782"
     CDS             complement(37154..38143)
                     /gene="galE"
                     /locus_tag="RD488_000782"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDT7656879.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38392..38559
                     /locus_tag="RD488_000783"
     CDS             38392..38559
                     /locus_tag="RD488_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HDT7656880.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38621..40432)
                     /locus_tag="RD488_000784"
     CDS             complement(38621..40432)
                     /locus_tag="RD488_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDT7656881.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40429..40794)
                     /locus_tag="RD488_000785"
     CDS             complement(40429..40794)
                     /locus_tag="RD488_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HDT7656882.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40957..41352)
                     /locus_tag="RD488_000786"
     CDS             complement(40957..41352)
                     /locus_tag="RD488_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7656883.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41370..42332)
                     /locus_tag="RD488_000787"
     CDS             complement(41370..42332)
                     /locus_tag="RD488_000787"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDT7656884.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42332..42544)
                     /locus_tag="RD488_000788"
     CDS             complement(42332..42544)
                     /locus_tag="RD488_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDT7656885.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42565..43263)
                     /locus_tag="RD488_000789"
     CDS             complement(42565..43263)
                     /locus_tag="RD488_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDT7656886.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43283..43825)
                     /locus_tag="RD488_000790"
     CDS             complement(43283..43825)
                     /locus_tag="RD488_000790"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDT7656887.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43957..44961)
                     /locus_tag="RD488_000791"
     CDS             complement(43957..44961)
                     /locus_tag="RD488_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7656888.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44958..45947)
                     /locus_tag="RD488_000792"
     CDS             complement(44958..45947)
                     /locus_tag="RD488_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7656889.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45944..46750)
                     /locus_tag="RD488_000793"
     CDS             complement(45944..46750)
                     /locus_tag="RD488_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656890.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46916..47872
                     /locus_tag="RD488_000794"
     CDS             46916..47872
                     /locus_tag="RD488_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7656891.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47949..48467)
                     /locus_tag="RD488_000795"
     CDS             complement(47949..48467)
                     /locus_tag="RD488_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7656892.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48555..48704)
                     /gene="rpmG"
                     /locus_tag="RD488_000796"
     CDS             complement(48555..48704)
                     /gene="rpmG"
                     /locus_tag="RD488_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7656893.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48932..49378
                     /locus_tag="RD488_000797"
     CDS             48932..49378
                     /locus_tag="RD488_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7656894.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49573..51468)
                     /gene="asnB"
                     /locus_tag="RD488_000798"
     CDS             complement(49573..51468)
                     /gene="asnB"
                     /locus_tag="RD488_000798"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDT7656895.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51793..52767)
                     /gene="bsh"
                     /locus_tag="RD488_000799"
     CDS             complement(51793..52767)
                     /gene="bsh"
                     /locus_tag="RD488_000799"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7656896.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(53103..53190)
                     /locus_tag="RD488_000800"
     tRNA            complement(53103..53190)
                     /locus_tag="RD488_000800"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53156..53158),aa:Ser,seq:cga)
     gene            complement(53335..53901)
                     /locus_tag="RD488_000801"
     CDS             complement(53335..53901)
                     /locus_tag="RD488_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7656897.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54156..55487
                     /locus_tag="RD488_000802"
     CDS             54156..55487
                     /locus_tag="RD488_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HDT7656898.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55453..55803
                     /locus_tag="RD488_000803"
     CDS             55453..55803
                     /locus_tag="RD488_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656899.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55895..56314)
                     /locus_tag="RD488_000804"
     CDS             complement(55895..56314)
                     /locus_tag="RD488_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDT7656900.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(56315..56659)
                     /locus_tag="RD488_000805"
     CDS             complement(56315..56659)
                     /locus_tag="RD488_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDT7656901.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            57009..57605
                     /locus_tag="RD488_000806"
     CDS             57009..57605
                     /locus_tag="RD488_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7656902.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        16227 a        12143 c        10069 g        19203 t
ORIGIN      
        1 accaagtcaa tcaaggattc atctcatccg ttgcgtccaa aagaaaccat atccctagaa
       61 aatcactaaa ttaccaaaca ccattagaag tttttttgag ttacgtaaat ggaaagtttt
      121 gtctcactta atttgacaaa taatacaatg taaaaaattc tgttttgcgg gatcgatttt
      181 atcattttat tggtcaagat ttttccattt ccaatccaat acttctggca gatcaatacc
      241 attttcacga atatagtttt gatgttcttg taatttctga tccatttttt ccgcaaaatc
      301 ttctgcttga cttcctttga tttttaaagc tgcgtctttt gccaaatgat aacgatcaag
      361 ttcatttact acacgcatgt caaatggtgt cgtgatatct ccattttctt tgtagccatg
      421 aatcattaaa tgatggttat gacgatcaaa gaaaatcgtg cggaccaatg tttcataacc
      481 gtggaaagca aataagatcg gtttgtcttt tgtaaaatat tgatcaaatt cttcatcgct
      541 caacccacgc ggatcttgac ttggatgacg taatttcaat aaatctacga cattgatgaa
      601 ccgaattttt agttttggga attcttccag cagcaaagtt acagctgcta atgcttctaa
      661 gttagattcc gttcctgcag cagcaatgac caattcaggt tcctcctctt ttgctgtcga
      721 agcccaatca atgattttca agccttcatt cactaagacg gctgcttctt ctgctgagta
      781 aaattgagca cgcggatgtt tggaagagat gatcaaattg attttttctg acgagcggaa
      841 tgctttatcc atgactgcga gcaatgtatt tgcatccgca ggcagatatt cacggatgaa
      901 ctccgccttc ttttctgcca aatgtgtcaa tattcctgga tcttggtggc tatatccatt
      961 gtgatcttgc tggaagactg ttgagcttgc aatgagattc agcgaaggat aatcttttcg
     1021 ccaagaaagg tcatgtgatt tccgtatcca tttgaagtgc tgagtcaaca tagagtcaac
     1081 cactcgcaag aatgattcgt aacttgcaaa aaaaccatgc cgtccagtca gaacgtaccc
     1141 ttctaagaac ccttcatctt ggtgttccga taattgactg tcgatgacgc gaccagatgg
     1201 cgaaagccat tcatcatttt ctggttcgat tttttccatc cattggcgat ttgtcgtttt
     1261 gaaaacttga ttcaatcggt ttgattttgt ttcatctggt ccaaatatac ggaaattttc
     1321 tggatttttc tcaatgatct cgcgaacgaa tttaccaagt tcggtcatat cttctgcttt
     1381 aacggagcct ggtttttcaa attgcaaagt atattttttc caatctggca taataagcgg
     1441 tcttggatcg attccaccat tggtgatagg attttttgcc attctttggt caccagtagg
     1501 cgcaatttct ctgatttctt ctaaaatacg tccttgtgca tcaaataatt tttctggttc
     1561 ataggatttc agccaacgga gtaaagcatc tgcatgatcc atatgttctt gatctacagg
     1621 aatcggtact tggtgtgctc ggaaggttcc ttcaattggt tccccgtccc attcttttgg
     1681 accggtccat ccttttggtg tgcgtacgat caatactggc cattttggca tcacgacatc
     1741 tgttgctgtc ttcaggcgag cttctttttg gatggatttg attttctcga ttgcttgatc
     1801 cattttttca gccataacag gatttaattt ttctggatca tttccttcaa taaagaaagg
     1861 ctcccagcca agtccgttaa agtaatttgc taattctcca tctgatttac gtgccaagat
     1921 cgttgggttg gctatttttg caccatttaa atgaaggatc ggtaaaacag ctccatctat
     1981 cactggattg ataaagacat ttgagaacca gcttccagct aaaggaccgg tttctgcttc
     2041 accatcacca atcacgacag cagagattac ttcaggattg tctaatacag ctccgactgc
     2101 atgtgaaaga gagtatccaa gctctccgcc ttcatggata gaacctggtg tttctggtgc
     2161 tgcatgagaa gcaatgcctc caggaaatga aaatcgcttg aataattttt gcattcctgt
     2221 ctcatcttcc gttacttctg gatagatctc tgtgtaactt ccatctaaat aagcattcga
     2281 taccatgact tgtccgccgt gtcctggccc ttcgatataa aacatgttca aatcatattt
     2341 attgatgact cggttcaaat ggacataaat aaaattttgg ccaggaatcg ttccccaatg
     2401 accgattgga tgttttttga catcttctgg tttcagtgta cgtctcagta aggggttatc
     2461 tttaagataa agttgcccaa cagaaagata attagcagca cgccaccaag ccgtcatttt
     2521 atcaaagtat tctttactag aataatccat acataacact ccttttcatt attactctta
     2581 ttctagcgca gatactccca attgaaacct aataagcact tctgttcatt tgtttggatt
     2641 ttatatctag ccaaatgaac aggtataaaa aaccacgaaa tttttccttt cgctgacgtt
     2701 ttttacattg atccaaaaaa cttgtcgtta tcacaatggc tgttccgcag ttcatttcgc
     2761 tcctcatcat gcataatttg ctgaatgacg ctaggccagt taacacattg ttggaaaact
     2821 ggggctggat cgagcaattc ctttcctgat tgatccgttt tatgtaaaag tctctgttat
     2881 ctttgtcaat atgtgaattg gtatcccagc tactatgcta atttctacag ggattatcca
     2941 aaatttggat cgtgaccaaa tcgaagcggc gtaatcggaa atatcaataa cttcaacgtg
     3001 atttttcttt taactgtcaa cggaccgaca aactcaaact tttatggtgc aggttccact
     3061 gatcttctag ttacttggct atacctgact gtcactaaaa tagattacaa tctagcttcc
     3121 gttatcggta tcttgatctt tatctatatg caaaaattta tatactatag aaaaaagaaa
     3181 gtcgaatttt ttacttttct ttttctcttt tttggttagc tgacacgcta ccagactaaa
     3241 gtcatggaac tcttaggtaa tacgtcttaa tgaaaacaaa aaaatcccgc aacccctgat
     3301 ttcacaggat ttgcgggatt ttttgattag tctttgttca agtcgcgaag caattcatcg
     3361 atatggttcc catagacaac tgattcatca agttcaaaga acaattcagg tgtcttataa
     3421 atacttagat tgtgccctaa ctctcgacga atcaatcctg atgctttatt caatccatct
     3481 tgtgcttttt tcttatctga tgctaagtca gataaaatgc tgtaatagat cgttgcttgc
     3541 tgtaagtccc ccgtaacttt cacatctgtg atcgttacgt tctccacacg agggtcacgg
     3601 acctttttgc gcaaaatatc attgacttct tttaagattt cttgaccgac tcggcgatca
     3661 cggtagttag ccataatgat tggcctcctt ttatcagttt ttagtcattt ttgacttctt
     3721 ccatgataaa tccttcaatt acgtcatcta ctttgatgtc attgaatttt tcaatcatcg
     3781 caccacattc ataacccatt ttgacttctt tcacgtcatc tttgaatcgt ttcagacttg
     3841 caagttggcc ttcatagatt acgattccgt cacggattac acggacaccg ctatctctac
     3901 gaatatatcc ttctgttaca taggcacctg caatcgtacc aactttagaa actttgaagg
     3961 tttcacgaac gatcatttga ccggtgattt tttcttcaaa ttcagggtct agcatccctt
     4021 tcatcgcagt ttcgatttct tcgatggctt tatagatgat acggtgaaga cgaatatcga
     4081 cttcttcagt atcagcttgc acttttgcct gcggtgtagg acgaacgttg aaaccgatga
     4141 taatagcgtt gctggctgct gctaaggtta catcactttc attgattgct ccgacagctg
     4201 aatggacgat ttttacacgg acaccttcca catcaatctt cttcaatgat gcagccagtg
     4261 cttctgctga accttgtaca tctgctttga tgattacgtt aacttctttc aattcgcctt
     4321 ctttcaggct ttcaaataag ttgtccaaag tcacacggct tgtggcagca cggttttcca
     4381 ataatgcacg ttttgcgcgt tcttcacccg ctgcacgtgc tgtcttttcg tcttcgaaga
     4441 ctacgaaacg gtcacctgct tgaggtacat cattcaagcc agtgatttct actggcgttg
     4501 caggtcctgc ttctttatcg cgacggccaa gatcgtttgt cattacacgg acacgtccgt
     4561 aagtattacc gacaacgatt gggtcaccaa cgtgaagtgt tccttcttgg acaagtaagg
     4621 ttgacacagg acctttacct ttatcaagac gtgcttcgat cactgttccg attgcgcgtt
     4681 gtgttggatc tgcttttaaa tcttctactt ctgcgactaa caggatcatt tccagcaatt
     4741 cttcgatgtt ttggccgaat ttcgctgaga tctcaacaaa aatcgtttct ccaccccatg
     4801 cttcaggaat taattcatac tcacttaatt cttgcataac atgctgagga tttgcacctg
     4861 gtttatcaat tttatttaca gcgacgatga ttggaacgcc tgcagctttg gcatggttga
     4921 ttgcttcaac tgtttgtggc atgacgccat catctgcagc aacaactaag atcgtgatat
     4981 ctgtgatact tgctccacgt gcacgcatac ttgtaaaggc cgcatgtcct ggtgtatcca
     5041 agaaagtgat tggtttacca tcaatatcga tctggtaggc accgatatgc tgtgtgattc
     5101 cgccggcttc gccgcttgtt acacgtgaat ggcgcaatgt atccaataag gttgttttcc
     5161 cgtggtctac gtgtcccata atcgttacta ctggcggacg tgagactaat ttatctggat
     5221 cgacttcttc tgcctcgaag aatttatcga tatcagcaat gtcaacttgg actttttctt
     5281 gtggttccat gccatagtcc gtcgctaaca gttcaatcgt atctttatcc agtgcttggt
     5341 tttgattgac catgacacca agcataaata attttttaat gatttctgct ggctcacgat
     5401 gaattttttt cgcaatatct gctacgttca taccttcagt atactctaat acatctggca
     5461 attcacggaa tttgcgtggt ggtacagctg gtttagttga ttgttgctgt ttgccttttt
     5521 tacctttttt attataacga ttacggttat tattattaaa tttgccgcga ttgttattgt
     5581 ttggtttgtt gttattgtta gtacggtttt gattgccgcc ttggctcgtt ccttgacgat
     5641 tttggctgct ggtatttccc gtattatttt ggtttgttgt tggttttttt ccttgattca
     5701 cttgaccgct cccttgaccg cgatcttgat aactgcggtt atttttattt ttttgttgat
     5761 tgttcgttgt ttctttttta cgttgatcgt tcggctgttg attggctggt tttctgcttg
     5821 cttgttgtgc agcttgttgt ttcgtgcttg ggtttttgaa cgcttgttgc aatttcttct
     5881 catcactgct agtaatcgca cccatatggt ttttcacatc gatgccaagt tgttgtgctt
     5941 tttccacgac gtctttacta gattttttga gttcttttgc taattcatag attcttttgt
     6001 tgcccatgca atcaccttcc taaccttcaa ttagctcctt ggtcttcttc gcaaatccgg
     6061 catccattat tccgaatacc ttgcgaggtt ttccgatcat ctgcgtgatt tctgcttcag
     6121 aaaatagctc aaagcaagga acttcataat atgaactctt atcttttatc ttttttcttg
     6181 tattctcact tgcatcggtt gccacaaaca ccaattttgc tttttgtttg cggatttcag
     6241 caatggtcag ttcttcaccc gtgattagtt ttcccgcgcg catcgctaga ccgatgagat
     6301 tcatggcttt ttgccgatta actgtattca ttttccaaat aactctttac gtgctttttg
     6361 gtgagtgaca tagtcaagaa gttcttgata aaactcatct gttaatgttg tttcgagtac
     6421 tcgatcgaga atttttttat cccaagcttg ttgtacttct tccggctcaa gtgagacata
     6481 cgctcctcgt ccaggcattt ttccagttgg atcgatcgat acttcccctt cttttgaacg
     6541 ggtgattcgg accatctctt ttttaggttt catttcacct gaaaccacgg atttgcgtaa
     6601 aggaattttc ctttgtttca tctctttgcc tccttactaa agttaagctt ctggtttttc
     6661 ttcgaccgtt tcattgttga atgcaattgt ttcatattca tcgtctgtta aatctgactg
     6721 aacgattgct tcatcatgca gttcttctgt ttctttttgt tgttcttgat tttcataaaa
     6781 ttccgtcatg tcagattctg atttgatatc gattttatgg ttagtcaatt tagcagctaa
     6841 acgtgcattt tgtccgcgtt taccgattgc tagcgataat tggtagtctg gaacgacaac
     6901 tgtgcaggcc tttggatttg tctcatcgaa gatcacatcc atgacttgtg caggattcaa
     6961 tgcatttgcg atgaatacag ctggatcttc attccattcg acgatatcca tgttttcgcc
     7021 ttttaattca ttgacgattg cttgaactcg ttgtcccttt ggcccgacac atgtaccgac
     7081 tgcatcgata tttggatcat ttgagcgaac tgccactttt gaacgatcgc cagcttcacg
     7141 ggcgatgctg acaatttcaa cgattccatc atagacttct ggtacttctt gttcaaataa
     7201 gcgacgcaat aggtctggat ggctgcggct aacaaatact tgcggacctt tagacgtatt
     7261 ttctactcgg gaaacataaa ctttgattcg atcatgtggt tgataaaatt catttggcat
     7321 ttgatcttgt ttagaaagaa ctgcctcaat tttaccaaga ttgacataaa tataacgttt
     7381 atcctggcgt tcgacgattc cttgcatgat gtctttttca taagcactga attcgttata
     7441 aataatcgtt ctttctgctt cacgtacacg ctgtaaaata acttgtttag ccgtttgcgc
     7501 agcgatccgt ccaaaatctt ttggtgttac ttcaaaacgg atcgtatcac cgatctcata
     7561 tgctggattg attaaaagtg catctttcaa tgagacttcc aactgtgaat ccatcacttc
     7621 ttccgttact tcttttaccg catagacatg gatctttcct tttttctgat caaattccac
     7681 ttcgacgttt tgtgcttggc catagtgacg tttgtatgca gaaaccaatg ctgcttctaa
     7741 agcatcgatc acgatttctt ttgagatccc tttttcagct tctaaagcgt ctaacgcatt
     7801 taacatttct ttactcattt ttttctgatt cctctccgtg attaaaattg gatagctaag
     7861 cgagcttttg caatattttt tcggtcaaaa gtcaattctt tttctcgtgt ttttatgcgt
     7921 attttcaatg taagctgttc agcatcaaat gattgaagaa atccttcata ttgtttttcg
     7981 ccatctactg gttggtataa ggagacatgg acataatcac caagtgcctt ttcatagtcg
     8041 ctttcttttt tcaatggccg ctctgctccc ggggaggata cctccaggaa ataagcttga
     8101 ggaatcggat ctggatctgc tgcatcaagt ttttcactca gtttctcact gacaaaggcg
     8161 cattcttcga tatcgatacc gccttctttg tcaataaata ctcgtaagaa ccagcttttt
     8221 ccttctttta caaattcgac ttcgacaagt tcaaaatttt gttcatctaa aatcggtgtc
     8281 accatttctg tgactgtttc aacgacgcta ctcaaaagtt tcgcctcctt aaaaattaag
     8341 tgcgtaattc cattaaaaag agtgagcgaa aaatccgctc actcacagtt agtatcatta
     8401 cctataagaa ctataccata ctctgcttaa aattacaagc agacaggaaa acagatgctt
     8461 atagcatatc gaataacgat aattgatttt catctggtag atctttcaat acgccattgt
     8521 cgttcatata ttcgatcaat gtttttgaaa ctttaccgcg ggtggcaaga tcttctttgg
     8581 ataaaaatgg accgtctttt cttgcttcaa cgatttgttt cgccacgttg gttcccaaac
     8641 ttgggacagc tctaaatggt gcgatcaacg tatcaccttc aataacaaag ttaacggcat
     8701 ccgatttata caaatcaatc attccaaatt tgaatcctcg ttccagcatt tcattggcta
     8761 actccagcac tgtcagttga ttcttttctt ttacggaagc atctaatccc ttgtccgtga
     8821 tttctttcat tgcttgtttc acagcatctt ttcctttgca catggagact agatcaaagt
     8881 cgtctgcacg tacagaaaag tatgcacagt aatacaaaat agggaaataa accttgaaat
     8941 aagcgacacg aagagccatc aatacgtaag ctgcagcatg ggctttcgga aacatatatt
     9001 tgatttttga acaagaatcg atataccagt cgggcacatt attttctttc atcgccgata
     9061 gataggtttc tcgcaattca tcagggatct tgttccattg tcctttacga acagtttcca
     9121 tgattttaaa tgccatcccg ctatctaatc cagcatggat caaataaacc ataatatcat
     9181 cacgacagcc gattacttcc gccagtgtcg catctcctcg tcgaatcaat tcttccgcat
     9241 ttcctaacca tacgtctgta ccatgagata gtccggaaat ttgcagtagt tctgcaaaag
     9301 ttgtaggatg cgtttcttct aacatccctc gaacaaaacg agtgccgaat tctggaatac
     9361 ctaatgtccc tgttttggaa taaatttgtt cctgacttac tccaagtact tcaggaccgg
     9421 caaatatccg catcacttcc gggtcatccg tagggatcgt ttgtgggtcg atccctgata
     9481 aatcttgaag catccgaata acagttgggt catcatgccc tagaatatct aatttcaata
     9541 cattatcgtg aatcgagtgg aaatcaaaat gagtcgtttt ccattctgaa ttttgatcgt
     9601 ctgctggata ttggatcggc gtaaaatcat agacatccat ataatcggga ataacgatga
     9661 tcccccctgg atgctggccg gttgtccgtt tgactccagt agcgcctttt gctaatctgt
     9721 cgacttctgc acttcgaaac tgcagattat tgtccctttc gtatcctttt acatagccat
     9781 atgctgtttt gtcggcgact gtaccaatcg ttccggcacg gtaaacatag tcttcgccaa
     9841 acaatacttt cgtatagtta tgggcttctg cttgataatc acctgagaag ttcaaatcaa
     9901 tatcgggcac tttgtctcca tggaatccta aaaatgtctc aaatggaata tcatgaccgt
     9961 ctttgtttaa gcgtgcacca cattttggac attgtttttc tggcatgtca aatccagaac
    10021 catacgtacc atcttcaaaa aactcggaat attggcactc tggacaataa taatgagggg
    10081 ctaatggatt aacttcagtg attcctgtca tcgtcgcaac aaagctagag ccaacagagc
    10141 cacgtgaacc tactagatag ccatcttcat tacttttatg cactagtttt tgggcgatca
    10201 gataaataac cgagaagcca ttaccattaa tagaattcaa ctctttttct aatcgttttt
    10261 gaatgatctc aggtaacgga tctccgtaca tttgttttgc ttttgtgtaa ctcaattctg
    10321 atatttcatc ttctgaacct ggaatcttcg gtgtataaag ttcatctttg actggaatca
    10381 cttcttcgca gatatctgcg attttattcg tattttctac tacgatctct ttcgctgttt
    10441 cttcccctaa aaagtgaaat gcagttagca tctcatcggt tgttcggaaa tggacatccg
    10501 gcaaactatg acgattcaac ggattcgctc cgcccataga attgatcaaa atttttcggt
    10561 aaatggcatc ttcttcgttc agataatgta cattacctgt tgcaacaacg attttatcca
    10621 aactttttcc gatttctacc aaattttgga taatttcttc caaatcatgt tcatttttta
    10681 ccaattcttg ctcgatcaaa ggcgcataga ccgcttttgg cataacttca atataatcat
    10741 agaattttgc tcggtttctt gcctcttcta cccctttttg catcatggct tcgaatattt
    10801 ctcccttatc acaagctgag ccgatcaata gattttcacg catctttttc aattgggagc
    10861 gtggtattcg tgggacgcgt tcgaagtatt cgacattcga cattgaaatc agtttgaaca
    10921 aatctttcag tcctgcctga ttttttgcta aaatcgttac atggaaaggt cgagcccttt
    10981 tgtaagaatc tccttctccg atatgctcat ttagctgatc atgataaagc atgttatgat
    11041 tgtccattgc ctctttcaca aagatccatg ctaagtgacc agttgcttca gcatcataga
    11101 ttgctcggtg atgctgttcc aagctaacac caaacttttt agataacaca cctaatccga
    11161 aacgtttgaa ttgaggatac agatatctag ctaattccaa cgtatcaatg actggattgg
    11221 ccgcttcagg aataccatac cttgcgtagc tagtattcaa gaaccccata tcaaaagccg
    11281 cgttgtgggc taccaaaatt gtatcttttg aaaattcaag gaacatccgc aatacttctt
    11341 cttccgactt tgaccctcga accatttcat ccgtgatacc agtcagatct accgttgttc
    11401 gtgacaatgg atgtcctgga tcgataaatt catcaaagct ttcgatcaca tttcctttat
    11461 acattttgac tgcggctagc tcgatgatcg tgtcatatac tgcagacaat cctgtcgttt
    11521 ccacgtcaaa tacgacgtat gtggcttcac tcaatgcttc atgtgcatca ttataagcaa
    11581 ttgggacacc atcatctacg acattcgctt ccacgccgta taagattttc acacctgctt
    11641 tttttccagc actatgtgct tccggaaagg cttgcgcacc accatggtct gtaatggcga
    11701 tagctcggtg tccccatttt cctgcttgtg ccacaagatc agagatgctg tttgttgcat
    11761 ccatcgtact catattgcta tgaacatgaa gctctactcg tttttcccct tcaggagcat
    11821 aatctttgcg aggtgtatgt ttgacttcta tgatatcttg cgcattcatg accaaatcac
    11881 ggacaaacgt atcttcttga atacttcctc gtacctttaa ccagctaccg acactgatcg
    11941 catcaaatac ttgttcatct ttttcgccgt tcgagaattt tttgacgata aatgatgaag
    12001 tataatctgt gattttcaaa gtcaagatct tgcgttttga acgtagttct ctgacttctt
    12061 tgtcgaatac gtacccctca agtgtgactc ttcgttcttc ttcaacgata ctgatcattg
    12121 gtgtcgttgg ttcatcggct ggaatatttc gtcctagctg gatgggtcct tcaagagctg
    12181 gcgattgctc ttttctttcc tttttctttt gttcgtggac aactagactt tcagctgctt
    12241 gcttcataaa ggcttctgcc tgttcttgtt tgcgttcttc aaaaagtttc aatacacgtt
    12301 ccgcttgctg ctcatccact tctggttcga tacgaaattt tgggaatccg taactgacga
    12361 acaactcttc tactaatggc aagtattgtt gcttcaaata agaaatagct cctgtactgt
    12421 cgattggcaa gatgacttta cgatctttta tcacaggtac ctgcgttttc aatacttgct
    12481 gtgctagtgg tgtatcgcat tgctgatttt ccaaagcttg ggcccagtaa tcttgcaaga
    12541 gctgttcatc gaatgtctgg tcatctgcta agatattcag tttgacttgt gcaatatctt
    12601 taaaagcgat agtcagatgc tgagtcaatg accgatatag cataataggc aaaattttgg
    12661 aaaaatgtag cgtaaattcc cataaacgcg atttacgatg gaccactaca ctatccattt
    12721 caccagcagt aagcagtgga tgattttttt ctgcttcctc tagttggatt tgttccaaca
    12781 gtttttcaaa taaatctcgt ttttctgaca aagatatacg ccctttctga tgagaaacaa
    12841 tgcaattgat cgcatcttat cctcttcttt ttcagtacct tttagtatac tcgttttttc
    12901 tgagttttac attaaaaaat tggaactgcg attcaaatcg cagttccaat tttaaaagcg
    12961 aatcatcaga ttgtcaaaaa cagctgattc agctattttt attttctgtg ttttaacgct
    13021 tattattcgc cttggttcaa gaggattggt aaagtattcg ccaattcttc tttacgtact
    13081 tcaaccattt cgccagtttt cttgattttc acttctacga ttccatccac tgctttttta
    13141 ccgacagtga ttctgattgg acagccaatc aaatcagaat ccgcgaattt cactcctgcg
    13201 cgttcatttc tgtcatcaac cagtacttca tagccagctt ttgtcatcgc ttcttctagt
    13261 tcattcgtca ggcttgtttg gtattcgtct tttagattca tttggacgat atgcagatca
    13321 aatggcgcaa ttccttttgg ccaattgatt ccttgttcat ctgaatgttg ttctacgatt
    13381 gctgataata aacgacttac accgatacca taacagccca taatcacaaa tttttctcgt
    13441 ccattttcgt ctagtacagt tgctcccata gattcactgt aacgagtgcc gattttgaat
    13501 atatgtccga tttcgattcc tcgagtaaag gcaagaacac cgttgttgtc tggtgaagga
    13561 tctccttctt gtacaaaacg aagatcttca taagaaagca cagtgaaatc gcgttttgga
    13621 ttcacatttt tatagtggaa tcctgtttcg ttcgctccag taatggcatt cgctaaatct
    13681 tggacataac ggtctgcata tacttttacg tcatctgaaa caccgactgg tccgacagaa
    13741 ccaaactcag cacctagata tttttgtgct tcttcttctg ttgcttcttc taaaaagtca
    13801 gcagataaaa agtttttcag ttttacgtca ttgacttcat ggtctccacg taccaaaaca
    13861 aggacaggtt gttcatccgc aatgaacaat acagacttga tgattttttg aggttcaaca
    13921 gaaaagaaat ctgctacttc gtcaattgat tttacgttag gtgtagctac tttctccaat
    13981 tcaagctgtg tttcatgcga tttttttgat acatagtagc ttgtagccat ctccaagttt
    14041 gcagcataat cactttcagt cgaataacag atcgtatcct ccccgatttc tgagatcgcc
    14101 atgaattcct ttgagtcttt cccgcccatt gcgccgccgt ctccgatgat cgagcgaaat
    14161 tctaagccac aacgcttgaa tacttcggta taggcttttt cgtaatcttt atatgtctcg
    14221 tccaaacttt cttccgttgc atggaaagaa tatgcatctt tcatgataaa ctctcttccg
    14281 cgaagcaaac cgaagcgagg tcgtttttcg tcacgatatt taggttggat ttgataaaga
    14341 tttaaaggta atttcttata tgaattgatt tcattacgca tcaaatcagt aaaagtttct
    14401 tcgtgagttg gtccaaggat catttttcga tcattgcggt ctttgaaacg atacaagttt
    14461 ggtccatatg tttcgtaacg cccggattct tcccaaagtt ctgctggcaa gatggcaggc
    14521 atcagcattt ctaccgctcc gattttttca aattcttccc gcataatgcg tttcagtttt
    14581 tccaatacac gatttgctaa tggcagatat gaataaatac ccgctgatac ttggcggata
    14641 tatccagctc ttagcaagat ttgatggctt aatacttctg catcatttgg aacttcgcgt
    14701 aatgttggaa tcaacatttt tgattgtctc attctatata ctcctttatt tcctcaaaat
    14761 agttatcgtt tgttattata ccctatttgt caactttttc tagaaaaaga atcgttgaat
    14821 atcgttccat gtaactagca ccatcaacaa cattaaaaat ccaaagccag ctaatgtcaa
    14881 tattccttct ttttcttgac ttaatggttt cccgcgaatc ccttcaaaaa tattcaagac
    14941 taatttcccg ccatctaagg caggaatcgg aagcagattg acgattccga gattcattga
    15001 aagaagcgcc atcaaactaa taacagttgt tacaccttga tttgctgctt ctgaagacaa
    15061 ttggtacatc atgacaggtc cgcctaattt atctaaactg aaacctgtaa atagtgatcc
    15121 taaggctttg aaaatttcca atgaaccgct gaaagcttga cgcgtccctc caatgatctt
    15181 atccataaaa cctgtattca ttggggcttt tataccaagt tggccaactt tttcgccatt
    15241 tgactctaca gatttcggtg tcacgtcgac agattgcacc tgaccttctc gttcgatctt
    15301 aaagtctaat gttttacctg gatttttcgt aatgactgtt gtcagatcat tccatgaatg
    15361 gatttctttt ccgtccacac tgactacctc atcattttct tttaagcctg cttctgccgc
    15421 agctccatta ggcatgatct ctcctacgcg attagtgttc gtcacttgaa caccaccttg
    15481 cataaatgcc agaatgatga ataacacgat tgccaaaata aagttattca tgggtccagc
    15541 aaagttggtc agcatacgct gccacaattt agccgattgg aactgtacgt cttttggcgc
    15601 aattctgatt tctgttccgt cgttttcaat aatcgtcgca tcgtgatcaa cagggtaggt
    15661 tactacttct gtttcgtctc cattcacata accagtgata gtcagctcat cttctaaatc
    15721 ataacggctc aattccatcg ggatagcatt tgtcaattgg attttcttac ttaaatttat
    15781 cttctctacg atgccgtcag aatttagtaa aagagaaaga ggcattcctg gtgccatttc
    15841 tgtttcatca tccccattgc ctgccattcg aacataaccg ccaataggta ataggcgaag
    15901 cgtatatgtt gtcccgtctt ttgcttgatg cccataaatt ttcggaccca taccgatagc
    15961 aaattcgcgg acgaggattc ctgatcgttt cgcaaagaag aaatgaccaa actcatgaac
    16021 aatcactaat ataccaaaaa cgatgataaa tgtcagaatc gttttcatag cttttttctc
    16081 ctttacttgt tttttgtgtt ttttataaaa caacgataaa acactataat tttaccatag
    16141 tataccaaag acaccaatag tatcaatata atgaaaaata aaaacctgcg tcttttatga
    16201 aattcacaaa gaaacgcagg tatacttact aaataatgcc aaataaatgc atgataggaa
    16261 atacaaacag caaactgtcg aaacggtcta agattccacc atggcctggt aagatatttc
    16321 ccgagtcttt cacatcataa tgacgtttga ttgcagattc gaccaaatca ccaaattgtc
    16381 cgactgctga aaaaataatc gtcatcagaa gcatgacaaa cataccatga ttgaatagtt
    16441 cttttgctgg gtatagcaat aaataaagaa atgcgactac aacagcacta ccgataccac
    16501 cgagcgcacc ttcaatcgtt ttgttgggcg aaatatcagg acttaactta tgctgaccat
    16561 aacgtcgacc aaccatatat gctccgatat cagttgccca aacaataaat agaccaaata
    16621 tcaaaacagc caagctttct gttcgtgcat tgacaaaatt ctggaaacct attcccacat
    16681 acaagctgac aagcacagga aaacctgctt catcaatcgt atacgtattt ttagaaataa
    16741 ctgatgttcc taaaagaatc ataactataa gataaaataa cataaatgta cttacattct
    16801 ctggaagaaa gaaaaaccat ctttcttttg gcaaaacaag taacactgca ccaacggcgg
    16861 ataaaactcc ttcaaaactt aagagtgtca atcctttcat ccggaacagc tcgtaaactc
    16921 ctactaccgc taagattgct gctgtaagct caaccgctat gcctccgatc catataatcg
    16981 gaataaacaa gactagcgcc acagctgctg tgatcacacg ttgtttcatg actgatcccc
    17041 tttctcatct tctgtttttt ttacaccgcc gaatcgacgg tctcgatttt gataagaggc
    17101 gattgcttct tcaagatgcg caccatcaaa atcaggccaa agcgcttttg taaaatacag
    17161 ctcactatat gcgatctgcc ataacagaaa attactaatt cgctcttctc cacttgtacg
    17221 gatcatcagc tcaggatctt gtaactcttt aggcaagaaa cctgtcatta aatgcttagc
    17281 aatcaattca tcatcgattt cttctgcgtg tatttctcct tttgctactt cttcggcaat
    17341 ttcttggaca gcagtcacga tctctgctct acttccataa ttcaaagcaa aattcaatac
    17401 cattccagta ttgttttttg tttgctcaat tgcacgtctt acagcatctt gcgtatgttc
    17461 tggcaatacg ttttcataac ccatgacatg aactttgaca ttttctttaa tcaattctgg
    17521 tacgaacgta tcaaagaagt cgacaggtag ttgcatgaga aaacttactt catcttttgg
    17581 tcgcttccag ttttcagtcg aaaaggcata aagcgtcaac actttcactc caagccttga
    17641 tgcttttttt gtgactttct ttactgtttc catgccttct ttatggccag caactcgtgg
    17701 caaacgacgg ttttgcgccc aacgaccatt gccgtccatg atgatggcaa tgtgctgagg
    17761 aattggtcca tcggtattaa attgaaattc gcttttttct tgaatatatt tgtttttttg
    17821 cggaaaaaaa cgtaacattc tttttcctcc tatacttaaa agattcccac tatcttaagt
    17881 attatagcaa tatctaactg tttttcctat gaaatcattg tttttttatt taaaaactga
    17941 ataatttttt ctttttttaa tttttaaata aaagaaatat aaataaaaac agaggaagcg
    18001 gaatgatccg cccctctgtt tttatgattt tattaaactt ccaataattc tttttcttta
    18061 tcagcagcga tcttatctac ttctttaatg ctgttatctg tcaatgtttg tacgtctttt
    18121 tctaatccgc gcaaatcatc ttcggtaata tcaccatttt tttgttgttt tttatattca
    18181 tcgatcgcat cacgacggat gttacgaatc gcgatttttg cattttctgc ttcttttttc
    18241 acatctttag ctaattcttt tctgcgttct tctgtcagtt gcgggataac taagcgaatg
    18301 acatttccat cattggttgg actgattccg atatcacttg ccataatagc tttttcaaca
    18361 tcttgaagaa tgctcttgtc aaaaggtgtg atcattaaaa cacgtgcttc tggaatttgg
    18421 attgatgcca tttggttcaa tggtgttggc gcaccgtagt agttcacagt aatacggtcc
    18481 aaaaggctag cgttcgcacg gcctgcgcgg atttgcccaa gttcacgttg aagattttgt
    18541 gctgcttttt tcattttttc ttttgcttct gtcataattg catctgccat ttttatttcc
    18601 cccttacagt tgttccgata ttttcgccta agattgcacg gcgaatattt ccgtgttcat
    18661 ttaaattgaa gacaagcagt ggaatatcat tatccatgct tagtgaactt gcagttgaat
    18721 ccatgacttg taatcctttg gcaataactt ccagatgagt cagttcttca aattttactg
    18781 catttgcatc tactttcgga tcagcagaat aaacaccgtc tacattgttt ttagccatca
    18841 ggataacatc tgcgccgatt tctgccgctc gtaatgctgc tgttgtgtct gtcgagaagt
    18901 acgggttgcc ggtaccgcct gcaaagataa cgatccgtcc tttttctaaa tgacgttctg
    18961 ctttacggcg aatatatggc tctgcgattt gacgcatttc aatcgaagtt tgcacgcgtg
    19021 tcggtacacc cacgttttcc aacgtatcct gtaaagctaa ggcattcata actgtagcta
    19081 acatacccat gtaatcagct tgagcacgtt ccatgcccat ttgtgctccg atttgtccgc
    19141 gccagatatt tccgccaccc acaacgattg ccatttcaac gcccagctcg tgaacttctt
    19201 tgatttcttg gatgatttct ttgattactg gtggtttgat tccaaatcct gcatccccag
    19261 ctaaagcttc tccactcaat tttaagacta cacgctgata tttcggtgtg accatgttca
    19321 ttcctccaat attttctatt gccattttac catacttaga tgatttcgac actctaagac
    19381 tggtttttct tgttttgctt aaaaaaaggg agcgcacaaa ccgtgcgttc ccgtctgtta
    19441 ttcaacagaa ttattttttc acttggctca taacttcttc tacaaagtta tcttcgcgtt
    19501 tttcgatacc ttcgccaact tcgaaacgta cgaatgtttt aacagttgcg ccttttgatg
    19561 caacgtattt ttcaacagtc atatcaggat ctttaacgaa tggttggtcc accaaagcga
    19621 tttctgcttt gaatttcttc aagcgtcctt ctaccatttt ttcaacgata ttcgctggtt
    19681 tgccttcgtt caatgcttgt tctgtaagaa cagttttttc atgttctaat tcagcttctg
    19741 gaatttgtga ttcgtttaca taacgaggat tgatagctgc tacgtgcata gctacgtctc
    19801 ttgcaactgt ttcgtcagtt gttccatcta gaacagtcaa tacggcaata cgtccgccca
    19861 tatgcaagta tccaccaaat gcagcattgt cgtctttttc tacaacttca aagcgacgga
    19921 agctgatttt ttctccgata acttgagttg cttcgatcaa gtcagattca attgtacctt
    19981 tatctgtttt gattttcatt gcagcttcca tgtctgctgg tttgttttca gcaacaagtt
    20041 ctgcaatttc ttttactaaa tcttggaaca tttcgttttt agaaacaaag tctgtttctg
    20101 agtttacttc aacgattgct gcagtgttac ctttcacagc aactgaagcc aatccttcag
    20161 ctgcaatgcg gtcatttttc ttcgcagcct ttgccattcc tttttcacgt aaaagatcaa
    20221 ctgctttttc catgtcgcct tctacttcaa ctaatgcttt tttcgcatcc atcattccta
    20281 cgccagtcat ttcgcgtagt tcttttacca ttttagctgt aacgtctgcc atgtttaact
    20341 cctcctgtgt gtttttcttt ttaaaaaaag ctgcttcaaa ggagagtgag gcttgtcgcc
    20401 cagcctttga aacagctcca tcattcaaaa ttattctgct gaagaattgt cgccttcaac
    20461 aacatctacg atttcttcga ttgatgttgc tgtgttttct tctgtgaaat cttcttcaac
    20521 tacttgatct tcaccttggt ttccttcgat gaaagcatca gccatttttg aagtaatcaa
    20581 tttaacggca cgaattgcat cgtcgtttga agggattact acgtcgattt catctggatc
    20641 gcagtttgta tcaaccatag ctacgattgg gatatttaat ttgtgtgctt cttgaacagc
    20701 aatacgttct ttacgtgggt caacgatgta cattacatct gggattcttg gcatatcagc
    20761 gataccgcct aagaattttt caagacgttc acgttctttg ttcaaaccag caacttcttt
    20821 tttaggtaga acttcaaaag ttccatcttc ttccattgca ttgatttgtt tcaaacggct
    20881 gatacgtttt tggatagtat cccagtttgt caatgttccg cctaaccaac gatggttaac
    20941 gaagtattgt cctgcacgag ttgcttcttc tttgattgct tcttgtgctt gtttttttgt
    21001 acctacgaat aatgctacgc cgccttcttc agcaacgctc ttcatgtaat cataagctgc
    21061 atctactaat ttaactgttt tttgcaagtc aatgatgtag attccgtttc tttctgtgaa
    21121 gatatatttc ttcatttttg gattccagcg acgagtttgg tgaccaaagt gtacgccggc
    21181 ttctagtaat tgtttcatag aaattactgc catgtttgtt tcctccgatt tggttttatt
    21241 tttcctcttc ttatcttcta ccttgccggc aaactttttc aagcacctac cgacaatcca
    21301 ataagaatgt ggatttgctg atgcataaag caccctcagc tattatacag acaaaagatc
    21361 cgtatcgcaa gagcaaatat acttttctgc tcaacattca atagtttacc tgaaagataa
    21421 aaagaattca agaaaaacag tagatttctc tttgtttctt tattatcctt tttccataaa
    21481 ataattttag gtataaaaga cgaatattat tgggcaatcc ttcttttttt tgttatgata
    21541 catgtgaaat ctttcgtaaa ggagaaagaa aatgcgcaaa gctcaaagac atttgctgat
    21601 taaacaagtc attgaagaat tcccgatccg tacgcaagaa gaactattaa acaaacttgg
    21661 gcattatggc gttaccgcca cgcaggcaac gatttctcga gatatccgtg atctaaaaat
    21721 cgtgaaggca cctgatgaaa atggcgtttc ccgcttcgta ttgtttcgcg aaaaaggaac
    21781 tcctgagact aggactgagg aagaggatcg gctggttcaa atgattgaag acattgtatt
    21841 gaaagtcgaa cgagtccact ttttgacgat cgtcaatacc ttgccagaca atgctcattt
    21901 atttgcatct gttttagatg agatcaaacc tccctctatt gtcagtacaa ttgctggatt
    21961 cgatacgatc atggtcatct cggaaaatga ggaggacgca aaacgagtag aagaatttct
    22021 tcaccatcca actgaagtat cactttttta atcagagcac gtattcctaa tatggaatgc
    22081 gtgttttttt attttcaata ttttccttat taaataaacc tttacactct ttacaaaaat
    22141 acatcatttt ttattcaatt ttttcaacac cttgattgaa tcacaataat catcatttat
    22201 attggatgtt aacaagagca gcttcttgct ctttgtgtat ttcaaaaaag aaatgaaagg
    22261 aaatcatatg tataaattat taactcctgg accattgacg acttctgaaa cagtgaaaaa
    22321 tgctatgctg atcgatcatt gtacttggga tcaagaatac aaagaaatta cacaatggat
    22381 aagaaaaaaa ttattggatc ttgctcaagt atcggaagga atatacacaa cggtcttaat
    22441 gcaaggtagc ggctcctttg gggtagaatc ggtattaagt tctgtgatca ggccagaaga
    22501 tactgtactg atttgttcaa acggcgcata tggacaacga atgatcaaca tgtgcgaatg
    22561 tctgaaactg aactataccg tttatgaggt atcggaacat caaatcctcc aagctcatgt
    22621 gattacacag ctgattgaag agaatccctc tatctccgca ctagcaatgg tccatagcga
    22681 gactacttcc ggtattttga ataatttgga agagattgct gctgtcacac aagaaaaaga
    22741 tcttttgttt atagtggacg cgatgtcaag ctttggtggg ataccgattc gtgtagccga
    22801 actagggatt gattttttga tttccagctc aaacaaatgt attcaaggtg ttccaggctt
    22861 ttcttttgta cttgctaata aagcggaact agaaaagcga aaaaatgtga gtcgaagttt
    22921 gtcacttgat ctatatgacc agtaccgcgt gatggaaaac gagaatggca aatggcgttt
    22981 cacttcccct acccatacgg ttttggcttt tcaacaagcg ctgaaggaac tagaggcaga
    23041 aggaggaatc gaaactcgat attcacgtta tctcgccaat aatcatgtac tacgacaaaa
    23101 aatgacagag atggggttcc agcctttcat tcaagaatat caggggccat tcatcacctc
    23161 ttttctttac cctaaggact ggcgatttga ttttaatcat ttttatcagt atttaaagca
    23221 aaacggattt gtgatctatc ccgggaaaat cagcgatcat gaatgttttc gtatcggaaa
    23281 tattggcgag atctatccgg aagatatttt ggaactgaca gcaattatca aagactataa
    23341 ggagaacgtt aatgattaaa actgtaattt ttgattgggc aggaacaact gtggactttg
    23401 gctgtatggc tcctgtccac gcttttagaa atgcttttct agaaaaagga atccaactga
    23461 ctgacaaaga aatccgcgaa ccgatgggaa aattaaaatg ggatcatatc caacagcttc
    23521 tttccctccc ttctgtcaaa aaacaatgga tagctattta tggacaacta cctcaggaaa
    23581 aagaggtgga ggaattgtat caacaatttg aacattatct gtttaaagat ttggtcaagc
    23641 attctacctt gaaacccgac acattggaaa cgatcgaacg gttgagaaac gctgggatca
    23701 atattggttc cacgactgga tttactgctc ctatgatgac aatcgtagca gaaaccgcaa
    23761 aaaaagaagg gtattcacca gacttcatgg caacttctga agacgtcgaa gggtatggtc
    23821 gaccgtttcc ttatatgatc cataaaaaca tgcagtactt caaaaacaag tcggttgatg
    23881 aagtaatcaa agtcggagat acggtctcag atatccagga agggaaaaat gccggagtgt
    23941 tgacagtagg tgtaattgaa ggtagttcgc taatggggat ttcttatgat gagtaccaaa
    24001 aattagagat ggggaaaaaa gatcgtttaa aacagtctgt tgctcttaga ttccaacaag
    24061 ctggcgctga tatttgtgta aacaatttaa aagagttaac agaatacatt ttgtacgctg
    24121 acaagaatcc agaatgactt ttatacaaaa tcagaggtcg tgaaaaagct gtactgcatc
    24181 aagtaataag aacagccaaa caaaaatagc tcctcatatt tttcgtttgg ttaggcttat
    24241 taccgcagat gcaagctttt gaacaccgtt tattcgaaaa aaaaagggag ctgtgacacg
    24301 acttttgtca cagtcccctt atttacaaac aaacagtgtt taagagacaa cctctccact
    24361 aaacggtgtt cattcagctg actctcggta tttgctcaaa aaacgataaa atttgaaaag
    24421 ctattttctc ttttgtttct ctaatactcg gatcagaacg ctgatttcac attctctttt
    24481 tcttacatct tatctggtgc atgaagtcct agcaaacgaa ggtcttcttt caataataca
    24541 gtcactgcat aaactagagc taagcgtgct tctttttgtt catcatcagc taaaatcttc
    24601 gtatgagcat agtatttgtt gaatgcttgt gctaatttga ttgcatgttt cgcaatcact
    24661 gacggttcgt atttttcccc agcagacaag accgtttcag ggtatttttg aactaattta
    24721 accacttccc agctggtatc gtcattcaat gcatagtctg ctgtttctga agggacaaat
    24781 cctgcttttt ccaacaggct gactgcacga gcatgtgtat attgcacata aggtccagtt
    24841 tctccttcaa atcgaacaac ttcttccagg ttaaagtcaa atgtattcag tcgatcgttt
    24901 ttcaaatcgt ggaaaatgac tgccccaacc ccaacttgtt tagctacagc atctttgttt
    24961 tccaaatcag ggtttttctc gctgatttgt tctttagcag attggattgc ttcatttaat
    25021 acttcttcta ataagacgat ctttccttta cgagttgata attttttacc accttgcgtg
    25081 atcaaaccaa atggaatatg gcgcatatcg tcagaccagt caaagcccat ttccttcaag
    25141 acagctttca actgtttaaa atgatagctt tgttcattcc ctactacata tagagattgt
    25201 ttgaagtcgt aagtacgttt acggtacaat gcagcagcta agtcacgtgt aatgtatagt
    25261 gtcgcaccgt ctgacttctt aatcaacgct ggattcaggt cataagcaga taggtcaacg
    25321 atctctgcac ctttatcctc gttcagcaaa tgtttttctt ctaaaagttt gacgatttca
    25381 tccatcttgt cattgtagaa agcttcaccg ttcaacgaat cgaaacgtac ttccagcaga
    25441 tcatagattt tattgaattc tttcatcgat tcatcacgga accattgcca taattgaata
    25501 gcctcttcat cgccttcttc cagacgtttg aaccaagcac gagcttcttc atttaattct
    25561 ggttctgttt cagctacttc atggaattgg acatataaac gaagcaattc attgattggt
    25621 tctgctttaa cagcttcttc tgtaccccat tttttgtaag cgacgatcag ttttccaaac
    25681 tgtgttcccc agtcacctaa atggttgatg cggattggct gataaccgat tttttccata
    25741 atgaaaccga tcgaattacc gataactgtc gaacgcaaat gtcccattga gattggtttg
    25801 gcaatattag gagaagacat gtcgattggt actgttcctt gattcccgat attgctatcc
    25861 ccataatgtt ctttttcttt cactactgtt tgcaaaactt ttttgctgat aagttcttta
    25921 ttcatgaaaa agttcaagta aggtccgaca acttcgattt tttcaaagtt ggcagaatcg
    25981 attttttctg ctaaatctgc agcgatttgc tgtggcgctt ttcggtaaac ttttgctaat
    26041 gaaaaggctg gaaatgcaac atctccgtgt tcagctgatt ttggattttc tagtaattgt
    26101 tcgacttgtt ccagtgttaa atcatctttg acagcgtcat agacagcttt tgcgacaaga
    26161 tctttattat tcatctttat tcctcctaaa gtgctccctt gattgttaaa caaaaaaaat
    26221 ctctagcgac ggcatactta gtatgccatc actagagacg agatttcccg cggtaccact
    26281 ccaattgtcc taaaaaagga ccagctccat ctgatatcgg tagacgaccg tctgtttaaa
    26341 acagaattct ccaagtgcgc ttcgttgtat cttcttcatt cggcttccac cacttccgaa
    26401 ttcgctagcc aagaatgata caagtactct cttgttcaac aaatcttagt cttattaaac
    26461 tttcttgaat tatatcagaa aaaaaaacga aaggctagtc gtttctgata aaaaaacaat
    26521 ccagatggcc taaaggagaa gaaataccac ctggatagct ataaatcatt tcgtaaatac
    26581 gaaagactta acaaattaat cagctacgat aatcgttcct tcttcagaag ctaaaagatt
    26641 ctcgatattt tctaaagaag tgatgattgc cttagcgttt ggttttgctt caacaaatgc
    26701 aatagctgcc tctactttcg gaagcatgct tcctggagca aattgctttt catcaatgta
    26761 ttgtttcatt tctgaaacag taacagtttc taatttcttt tgatctggtt tttggtaatt
    26821 gacatacaca ttgtctactc ctgtcaatac gatcagcaaa tccgcatcga tgatttcggc
    26881 taatttttct gaagcaaaat ctttatcgat tacggcttct cgtccttcta atccagtagc
    26941 tgtttctaca acaggaatcc caccgccacc aacagagact gtgataactc cttgatcgac
    27001 cagcgtttcg atgacacgtg cttctttaat cgagatgggt ttaggggaag cgactacttt
    27061 tctccatcca cgtccagcat cttctttgaa tgtcacagtg gagtcagcat tcatttgttc
    27121 tttggcttct tcttccgtgt agaatggacc gactggttta cttggatttt tgaatgaagg
    27181 atcattttca tccacaataa cttgagtgac taaagaaacc acatctttat cgatcccttt
    27241 ttccttcagt acttcgccca tggcattttg taaccagtaa ccgatagatc cttctgtcat
    27301 tgcaacacat gtatctaaag gcattgccgg tgttttctca gaatcagcag cttgctgctg
    27361 aatcaatagg ttaccgactt gcggaccatt tccgtgggag atgatcaatt catctccttg
    27421 ttcgataaat ttcactaaat actttgctgt ttccattaac gcttcttgtt gggcttttgc
    27481 acttgcatcc gtagacaaga ttgcattacc ccctaaagcg acaactactt ttcgtttggc
    27541 catttcattc gtcctttctt cagttctacc gaattttcta gataacaaaa cgagccagcg
    27601 ttttgtgatt ttccctcaat gctgactcgt tttttcgtga gatgaatgtg gttatgctta
    27661 aacgcgaggg ataaacaagt tacctaatgt tgctgccatg atcgctttga ttgagtgcat
    27721 acgattttct gcttggtcaa attgacgagc atatttgctg cggaagactt catctgttac
    27781 ttccatttca gtgatgccaa agcgttcttt catttgttca ccgtaaacag tgtttgtatc
    27841 atggaaagct ggcaagcagt gcaagaagat caaacgatct gtgttgtgtg ttttttctac
    27901 catttccata ttgatttggt aaggtttcaa caatttgata cgttcttcga atttatcttc
    27961 ttcacccatt gatacccata catcagaata aaggacgtct gctccgtcta cacctttatc
    28021 aacatcgtcg gtaatcatca attgtgcacc ggatttttca gcaaagcctt ctgccatttt
    28081 gacgatttct tcttcaggtt gtaattcttt tggtgcaacg atacgcatat tcgctcctaa
    28141 aattgcacct gtgactaata aagagttagc catattgttt cgaccatctc cgcagtaagc
    28201 aacagtgata ccttctactg ttccaaagtt ttcttggata gttaaaaagt cagcgatcat
    28261 ttgtgttgga tgccattcat cagtcaagcc attccaaact ggaacaccag agaattctgc
    28321 tagttcctct accatttttt gactgaatcc acggaattcg attccatcaa acatacgacc
    28381 tagtacttta gctgtatctt ctgtggattc ttttttacct aattggatat catttgcacc
    28441 tagatattca ggatgtgcac ctagatcgat cgctgcagta gtaaatgcag aacgagtacg
    28501 tgtagatgtt ttttcaaata aaagcgcaat attttttcct tctagatagt gatgtgggat
    28561 accacgtttt ttcaagtctt tcaagtgttc tgaaaaatcg atcaaatatt gtaattcttc
    28621 ttttgtaaag tctttttctg ctaataagct tcttccttgg aatactgatt ctttcatatt
    28681 aaacattctc ctttagattg tttttattta agattaaaga ggaaatcccg acggcagctg
    28741 acagtaagac cgccgtcagg aaacaaatta cttcaagtct tcacggacaa gtggttggct
    28801 catgcagcgt ggaccaccac ggcctcgtga caattcactt gaattgattt ctaacacttt
    28861 gatgccatag ctacgaagca attcgttcga tacataattt cggttataag tgactacaac
    28921 acctggagcg attgccaatg tgtttgatcc atcattccat tgttctcgag gtgcaacgat
    28981 ctcatctcca ttaccagttg ggatcagtac aagatcatct aatccaagag cagctttcat
    29041 cgtttcgtgt aagttatctg aatgagtaat cttgatatca tcaccatctg gttcgattgt
    29101 aaagacatcc atcttaccgt ctttactttg aattgctgga tggatagtga atttatcgtg
    29161 atctaccatt gtaaatacgg tatccaaatg catcattgca cggttgtttg gaattttgat
    29221 tgctaacact ttttcaaatc ctgaattttt tgcgaatagg tggcgtgcta atttttctaa
    29281 agctttcgca ttagttcgtt gagaaatccc aacagctact actttatcgc ttaagatcaa
    29341 ttcgtctccg ccttcgatat gatctggatt ttcacgatcc aaccatactt cgattccttt
    29401 atttgcaaat cttggatgat gtttcaaaat atattctgta aacatcgatt cacgacgacg
    29461 tgcttcaaaa gtcatcttat tgactgtcat cccatttccc attgatgcgg aagggtcgcg
    29521 tgtaaagtac aagtttggca ttgggtccat gtaaaatgga tagtcatcgt ctgctgacag
    29581 atcgtataga ctgctagaac gtacttcaat atcttttgta cgaaccccag ccatgatttt
    29641 atctaccatt tcttgcgttt ccattgatag aaggaactca tgaagaccct ctcttacagc
    29701 attcgatgca atatgagatt catccaacat tttattcaag aattgttctt tgacattgcc
    29761 tgcgtcaatc gcttctgccg ctaatttttc caagtaaaga gtctcgacgc cttcattttg
    29821 caatgtcttt gcaaagttgt catgttcttc ttgagcaatc ggaagatatg gaatatcatc
    29881 gaacaacaga cgatccataa tatctggtgt caaattttcc acttcttgtc caggcctttt
    29941 cagtaaaact gtctttaatt tccctatttc agagaaaacg tgaataggtt tatccatgtt
    30001 gtgttgcctc cttctttttg attacatgta taggatatcc tccttttgta atcactttca
    30061 taattttgtc tcattcaaaa tgagacattc ctcacattaa tattcgataa ttaaataatt
    30121 aaacgttttt ctatttttaa gcgtaattta ttcatttttt attctgtata cactttcaaa
    30181 aaaatattta ttcattgaaa aaaatttttt gaataaatta aaaaaataaa ttatattagc
    30241 gttgttagcg tttactatat gtattattgt tgttttttat acacaaatca ttcgcttcaa
    30301 aacaaattat tcaataccat tgtatatttt ttacataata acaaattata tttgtaaagt
    30361 attaaaactt gtttctaatg ttggtatgtt aaaactttac aaattcttta aaaaaagtga
    30421 caataaatat agtgaacaat aaggagagga ctttttaatg cgtgttaata aaatcgattt
    30481 tcacttttca aaactcagat atcaacctga ttttgaacat ttctcggatg aagagttcca
    30541 acagatcaag gaacatactg ttcttcgttc ttataaaaaa ggacagatcc ttttcgacga
    30601 tggtgatccc agacaacggt tgtatatctt gaccaaagga ctcgttcgtt tagaacgtta
    30661 tgatgaaagt gcaacttatt actactatga ctatgtgaat acaaataacc tttttcctat
    30721 gtcaggaatg tttggagaag agacctacac ttatacagct caagcgatga ctgatattga
    30781 aacattctac cttcctgttt cctactatga aaaattagca cgaaaaaatc ccgaacagtt
    30841 gatctatatg atacaaaaaa tttctaaagt agttgaaata catgaattgc gtatccaaat
    30901 cggattgacc tctagcgcct ttgaccgggt aaaacaaaat ttattcattt tgaaagaaga
    30961 attgggcgta ccaacaaaag atggtcatat caccattcct tatccgatca ccttaaaaga
    31021 attagcagtg aatagcggca cgacacgtga aactgctgga caagtaatca aacaactacg
    31081 tgattccgga ctgttagatt atgacaaaaa gcgttttact ttctgtaaga cagctactac
    31141 tccagctatg agagaataac gcgaacaaaa ataagcagtg accctgatat ttatcagggt
    31201 cactgcttat tttcctccct aaaacttctg aaagatccgg cagttttaga tcactgggca
    31261 agactcaaag attttctatg tgtgtttcag ttatgtaata ttcactgttt gcaaaaaata
    31321 ctgatagatt aactagagga agcgtcttgt cctcatccga cctagattat tcgatattcc
    31381 tcgacaataa acgattaatc agtgagggca atcagaggaa cggataatga tgaataagct
    31441 gtaaaaaata gggctttgac aaaagcgtgt cacagccctt atttcgatta aacggtgtgt
    31501 acctgtcaac tcttcggtca caagtcataa tgttcataaa catgaggagc tgttttttga
    31561 aattgttcct tgtgaatcag agttaaacga caggcttacg aactcttgat taaacggcgt
    31621 tcaaaagctt gcatacgcgg taataagaac agccaggtca aaaacatgag aagccgtttt
    31681 tcctgggctg ttcttattac ttgatgcagg gcagattttt cacaacctct ttattcagat
    31741 aaaaccaagc ttggatcagc attcaactga tagctagcaa aatttctttt ttgcatttcc
    31801 acatgtgctg ctgctccaat cattgcagca ttatctccac aaagtcgaag agggggaatc
    31861 actagttcta cctcagggag tttagttgcc aaagcatcct gcaatccttc acgcaaccct
    31921 tgattggccg ctacacctcc agctacaatc agttgcttga ctggataatt ttgacaagct
    31981 cgaagtgttt tagtaatcaa tacatcgatc acacttgctt gaaagctagc tgctaaatca
    32041 tttttgtcta gatcttctcc acgctgttgt gcattatgca ccaaattgat aaatgcactt
    32101 tttaatccgc taaaactgaa atcataatta tcttcatgga tcatcgctcg tggaaaatgg
    32161 taattatctt ttccctgatg agctagctga tcgatttctt ttccgcttgg gtaagaaaga
    32221 cctaatactc ttccaacttt gtcataagct tctcctgctg cgtcatctct tgtctcccca
    32281 atgatttcat atgatccatc ttcttgcata tagactaatt ctgtatgtcc tccgctaaca
    32341 agaagtgcca tcaatggaaa ctggaatggt ttaaccagac gggctgcata gatatgccct
    32401 gccatatggt ttacaggaat aagcggcaat tggtgtgccc aagcaaaagc cttagctgca
    32461 gaaataccaa tcagcaacga gccgacaagt cctggtccat aagtgacagc gactgccgat
    32521 aaatcttctg ccgacacacc agcttctacc agtgcatctt ccaagcataa ggtgatttgt
    32581 tctacgtgat ggcggctagc tacttcagga actacgccac caaaacgttt atgactgttt
    32641 atttgagaag caacgatgtt agataagatc tctgttccat ttctaacgac cgctacactc
    32701 gtttcatcac aacttgattc aatcgccaga atcaattctt cattcatttc atcgtctccg
    32761 tttttaactt tctgctcata atgatcgcat cttccgtcgg attgcgataa tatgatttcc
    32821 gtttacctaa tatacgaaac ttttctgatt cataaagttt tcttgctgct tcattagata
    32881 gacgtacttc taaaaaaaca tgcagcgaat cttttatttg ttccgtaatc agtaattgta
    32941 acaaatgccg tgcatgccct tttccttgtt ctgaaactgc aacagcaata tttgtgatct
    33001 cgacttcatc tattactttc gagtatccaa taaagccaca gatctggtta tcttcaacta
    33061 aaagcagata atcagagtga ggctgttgga tgtctgccaa aaactgcatt ttcgtccaag
    33121 gtgaaccatg tggataagca ttttcgctaa tcatccatac gcattctgcc aagtacgctt
    33181 catcaaaatc tttttttctg caaatcaact aatctcactc attttctaaa agttttatca
    33241 tatccaacgc atcttctttt gtttcagtgt aatatctttt tttgatcgtt gttgcttgaa
    33301 aacctaactt ccgataaagt ctttgtgcat cttgattact catacgcact tctaatgaca
    33361 tcgtctcaca gcgattcatt atagcaaagt tctcgatttc gtcaataagc agcgaaccga
    33421 ttcgtttacg ctgatatgcc ggtcgaacgg caatattcgt gatatggcaa tctaaaccga
    33481 acgctcttga accgataaaa ccaatcattc ttccattatc aaagatacct agatatagat
    33541 gaggaagcgg tgacttcaat tctgatataa aggcactttt tgtccatggc aattcgccat
    33601 tatagacttc tcgttcgaca tccagcagct ctttgatatc ttctgtagtc aattctctta
    33661 gtacgtaacg acgatcgatt tgttcgattg ttttttctgt ataaatcatt ttatcttgaa
    33721 aaaagcttct ggcatacgct ctaaattttt tcaacataac tttcgtctcc aggtgtgtgc
    33781 gtctccaacc atttttcttc tgcttctacc cgttttaaat agcgaggaag aaaagcttgt
    33841 ttctctgcaa ctggttcagc taaagcacct aattgagcca cagttacacc acttggaata
    33901 tcccatgctg gaactgtatt aatcatcgca ctaggcaata tttcctttat ttcatagaag
    33961 aatttgtgac aatcactccc gacgaaataa atagcttcat tcagcttttg tagttgtgtg
    34021 aacaaatcag aagcagaaat atgtacatct tcaagtacaa tttctaatct attttctttc
    34081 cagcggtatg ccccagcgta tacatttttt cttcgagcat caaacatggg cacaataatt
    34141 ttatccacac cgatgcaatt agccgcgatg gttttcagac tagatactcc tactagctct
    34201 ttatctaatg tataagcaat cgtttttgct gtcgttacac ctatacgaag ccctgtataa
    34261 gaaccgggac catcagaaac cgcgattcgg tcaatgtctt ttggacttat ttgaagatct
    34321 gcaaacaatt ggtcgattgc aggcatcagt gttacactgt ggttgcgttt gatatttgtt
    34381 tgtatttgtc caagaatttg ttcgtcttct accacaccga tcgccaaagt ttggtttgca
    34441 gtatctattc ctaatgtaat catatatttg atcctttctg ctatgacatt ctcgccttcc
    34501 attgtagcat acttttttat tctgaggatg aaaataccaa aggcaaaact agtacaatga
    34561 tacatgatta tctgctggcg ggcaaatttt gccccttcct gaaacacaaa aaagctgcgg
    34621 tatcacttca tttccccaca gcttttccat cttttatttc gttgattctc gaataatcaa
    34681 ctctgtttcc acaataatct ttcttgaaac cggtgctttg gaattactta attgaagaat
    34741 cgtctccact gctagctctc ccatccattc ggtataaact tttacagtag aaagagaggg
    34801 cgttacatat ttcgctacac tgacatcatt gaaacccatc acagaaatat cttctggtac
    34861 cactaaacct ttttcttgaa tcgctttcag tgcgccaatc gctaatgcat cattagctgc
    34921 aaaaagcgca tcaggaacat gcggattcgt ttttaaatac tgcttcactg cttgatatcc
    34981 tgactcgaca gaaaaatctg cttcgataat tggaccttcg tcgtagcctt tttctgccaa
    35041 aacttgttga aatgccataa ttctgggatc ttttagccgc tgatggtttt tcttcgtata
    35101 ttctgttcca gcaagcatag cgatatgttg cgctttatgg gagacaaaat gttcaatgac
    35161 tttttgaaca cttgacttaa agtcgacaac tagagagtcg attccttgag aagtgccgtc
    35221 agaatctacc aaaagcaagg cattttggga tcctttcatt tctaataact gagcttcgtc
    35281 gaattttcct agtgcgatcg ttccatctgt cggaagatca ctaatggaat cccacgtttc
    35341 tttcaataaa gtaacgtttg cttcttctgc ctttttttcg attcctagac gaatagataa
    35401 ataataaaga tcttcaagct cttccgtatc gtcgtaccac tggatcaggc gaagcgtttg
    35461 cttagtattt gctgcatttt tacgatgttt cgtataattt aagcgttctg ctgcttcaaa
    35521 aattttttgc tttgtggcta agccaacgga aagatcagga tcatagttga gaactcttga
    35581 aacagtagca ggagaaactc ctgccaactg cgcaatgtct ttaattgttg ccatttgtct
    35641 ctcctccttt tttacgttta taaaattgca gtaaatcgtt caaacgctgc ctgtcctttt
    35701 tcatctcgct tgaatactcc agcgtcttcc agtacacgtg caaaaacctg acctacagat
    35761 ttttgtacga catcggtgac cgtatctttc gtcaaatcag gatgttcttt ttttaattgt
    35821 tctgcccacg gacgatgata ttcagccatc tggttttctt ctcctaataa gaaatgctct
    35881 acttctacta gttctggttt caaacgaggt ggtaaaacag caagccccat tacttcgatc
    35941 aacccaatgt tctccttttt gatatgttgg acatctttat gtggatgaaa aatcccatca
    36001 ggatgttctt ctgaaacatt gttgtctcga aggacaaggt ccaactcaaa gtaattgtcc
    36061 cttcttcgtg caattggcgt aatcgtatgg tgtggtgtac catctgctga aaaagctctg
    36121 atagatactg tttcatccga atatgctttc cacttttcca atactgagtt agctgcttca
    36181 atcaacaatt ttttctctgt tgattgcaaa cggatcacag acatcggcca tttcacgact
    36241 cctgcgatga cttgcggata atctgctagt ttgataagtt tttctatcgg tgcttttgcc
    36301 ataggaaatt catgacgtcc tgcctgataa tgatcatgag aaagaatcga tcctccaaca
    36361 atcggcaagt cagcattcga accaacaaag taatgaggca agacttcagt aatccgaagc
    36421 agtctagcaa atgtttcctt tgtgattttc atcgggcggt gttgttctga taaaatgatc
    36481 gaatgttcat tgtaataagc ataaggagaa tattggaatc cccagctttc accgtctaga
    36541 ttcattcgaa taatccggtg attggtgcgg gctggatagt tcaagcgacc tctatatcct
    36601 tcgttttcca tgcaaagcat gcaggtagga tagtctactt ttaccgcctc gcgttctgct
    36661 gcgatttgtt ttggatcttt ttctggctta gataaattga ttgtgatttc cagttcacca
    36721 tactccgact ctgccggaaa tttgatgttt tttgcgatgg ctcttgtttt gatgtagtca
    36781 tttttcttac ttaaattaaa gaaatactca gttgcttcct ctgggctttt cgaatagtgc
    36841 tgtgcaaaga atgcattgac gactgaaggt ggcggtgtga gaaaatccat taattgcgct
    36901 tcaaaaatct cttgttctgc tggcaattct gaaagaacac cattttctct tgccttagcg
    36961 acaagctgat ccaataagtc tacagattct tccttaactg gtcttacttc aatgctttct
    37021 agagcatctt ctcctaccat ccctaaaaga cgattctgta aatataagcg gtccatttcc
    37081 atccatccgc cagcttcgat cgcaagtgtg gcaaaatcac aaatcgtttg actgattgac
    37141 atatctcatt cccctattct tcataaccat ttggatggct gacatgccaa tcccatgctg
    37201 ttttgataat tgctttgata tctgtgtatt caggtttcca acccagaacc tctctcgctt
    37261 tttcacttga agcgactaat cggctaggat ctccagctct tcttggtgct atttctgctg
    37321 gaatttcttt tcctgtcact tctctagctg cttctagcat ttccttgact gagtatcctt
    37381 tgctgctgcc taaattgaag aagttgcttt catttccttc tttcaagtat tccaaagcta
    37441 aaatatgtgc agcaatcaaa tcttctactt gaacataatc tctgatacat gttccatctg
    37501 gtgtatcata atcgtctcca taaacagcca atgcttttct ttgaccaaga gctacttgta
    37561 aaatgattgg gacaagatgc gtttctggtg tatgatcttc tccgatagat gcatctgctt
    37621 ttgctccggc tacattgaag tagcgcaaag cgacatagcg catgccatat gcttggtcac
    37681 accacttcat cattttttcc atcatcaatt tactttcacc atacggattt ttaggattag
    37741 ctggtgtatc ttctgtgatt ggagactctt ttggttctcc gtaagttgct gcagtagaag
    37801 agaacacgat tttattcaca ttgaactcgt gcatgacttc aagtaagatt tgcataccgt
    37861 atacgttgtt gttgaaatac atcaatggtt tttcgacaga ttctcctact aaagagcttg
    37921 cagcaaaatg gattactcct tcaatcggtt ccttttcaaa tacggaacgt agaaattctt
    37981 tatcccggat gtctccttca taaaaatgag catctggatg tactgcttgt ttgtgacctg
    38041 tgagcaaatt atctaccaca gctacttgat accccttttg aactagctgg tctacagcgt
    38101 gcgaaccgat ataaccggct ccgcctagta ctaaaattgt cataaaaaac actcctttga
    38161 ttagtaaaat tgtgtttgtt gattatatat aatttaaaaa aacgaagttt acttttatgg
    38221 tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta aatttataat aaaacattta
    38281 gtaaacattt tcaaggattt tttgcaaagg tttacaaaca aacgtaaaac tagccttttt
    38341 ttctcttttg ttccataata gatataacaa ataataaatg aggtggattc aatgaaaaaa
    38401 tttgtatctg gaatattagt aggaagtctg gcaacagccg ctgccgttgc tggtttggtc
    38461 gcttctgtga aaaaaacagt gatcgatcca attgacgaaa aagaagcaat gatcgaagaa
    38521 aaccgtaaaa aagcaatgcg caaacgcgtt tctcgttaat aattatttaa aaacacgcat
    38581 gaagacttgt gaaagaacag ataagtcatc atgcgtattt ttatttgtca gtcaatataa
    38641 gttgtgctat tttatctgcc tgtctcagat tccatggatc tgtataaggt ctagctactg
    38701 ctgcagttag ccaatccaca ccttcaacag gtattccata gcaataaaag tcagactgga
    38761 tttcccctga agcatcaatc acgcgattcg tacctcgctc aacatctata gcttctgaat
    38821 gataacttcc tgtattatct gaaaatgaaa aagggcgaac aagtttgttt tccttcaaat
    38881 tttttatgac aggattactt gaacgagaaa agcttgtttg tggcaatcga gcttcaatca
    38941 aatagcgact gctgatttct ttatcttgta gagaaataac atagcggttg tgcttttgct
    39001 gaatatcaaa tggcggttcg aacaaatgaa aaatacccgc atctatcagt gctgctaatt
    39061 ctttcgtccg aatgactggc ggaccgatcg ttaaaaagct atttagatga gtaaaccatc
    39121 cccatagtat ttctttgtat tcctttgcag aaaaaacgtg ccattcaata gcctgccgga
    39181 ttggatcacg ccagtctttt aatgcatcaa atgttgaagc aaatgctcct gtgcaattgc
    39241 ctttttccgc ttcttttatc tgcccttcaa taaatgctcg gctagcttct gcaaaggact
    39301 catcctgata ggtaagagga atttctaaat acgaccaatc ccatctataa gggattagtg
    39361 ctggatgctt tccgagacac tcctctgaag agagggagag aaaatcatgc tcaaaatttt
    39421 tctttggaat cggcaaatga tattcttcga tgattttctt gtaataaaac aactcaacgt
    39481 cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa tcccgactga tgccattgct
    39541 ccaggttttc ttttgttagt aaccgtggcc atgccattga tccgccttgc ttttggtttc
    39601 ttcctcgagg gtaataaggg agcccccttc ttgatccact gtatacaatc ggttccttgc
    39661 ctgatggatg atagacaagt tttccttttt cgttctcgaa gcgcccttct cttgatactg
    39721 taaacaatcc gacataatca aaaaaactta agcctagacc tcttaaaaag acattttctt
    39781 taggcggtat cttcgaaaga tcgacatctg caggattaga aggaagctga tacagtaaat
    39841 catttttctt tgcgtagtct acccacactc tttcttcttc tgtctcatca ttttcccagt
    39901 gaccgcttgc taaaacaagc tgatcgatag aatagctttg ctgatctgtc tgtaaaagat
    39961 aaccatcttt tcttttgctg acttttttta ctaaagaata aacaaactga atagaagctg
    40021 gaaattcttc ttgcaacttt gagaaaaacc agcgttgata gagtccgtat aaacatcgag
    40081 tagattgctg atctttttcc agacgattga tttcttctat aattagttgc ttatttttgg
    40141 ttaccgtctg ttcgatataa tctgtagcag gtcctttact ccattgaaac aagttgggtc
    40201 cctgtgttac caatcctcca ctggacaatg tttcatctgt aaaaagcgtc acttgttgag
    40261 aaacagaatt cattaataac tccggtggct gattcaaccg ccaaactcga cctccaggac
    40321 cattgggatc gaaaagaaaa agttcaagag aatgtctgtc ctgattatta tggagaatcc
    40381 tttctgctat acttaatcct ctaggtccgg caccaatgat ccctattttc atttgcatgc
    40441 ctccatttcg ataaattttt tcaataaaac agcatggttc tgatgttcat tttttgcacc
    40501 ataaacaaaa gtaatgactg gatgttcttt cataagttga ctgagtttaa aaatagcttg
    40561 cttcttttct tcttcgaaaa tcaattcttg ctggtatttc tttgcaaatg aagcaaatcg
    40621 ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta ggtgcaattt ctttcaacca
    40681 cagatctaac tgcgcttttt cttttgaaat tcctcgtggc cagaacctat ccacgagtat
    40741 tctatagcca tcctcttttt cagcatcaag gtaaacacgt tttaatttga tcatagttgt
    40801 ttccttcttt ctgccttttc gcttagctta tatatgtaga taatagcaca aaataaaaaa
    40861 aatgaacggc acaactatcc attgcgccgt tcatgtgatc ttggtcaaaa tctaatgatt
    40921 gattcggttt ttaaagctgt catacaatca tctgttttat acttttttac ttttgatttt
    40981 tccagaccat ccgtcatatc cacccttaag taaataaatc tcttgataac ctgctttacg
    41041 taatttattt gctgtacgga tgctcaagct tttcttttga tcgtaaatat agacaggctg
    41101 gtcttttcga atagatccta atgaatcttt caaaacagtg taagggatgt ttcttgcacc
    41161 taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca tcgattactt gtgcttttct
    41221 cattccttct cgaaattctt cttctgtcaa agtcgttgct gaacgcttgg ccattactcg
    41281 tagatagact tcccaaaaga tgattgcaag cacaatcaat agcaaaatga tattaattac
    41341 ccataaaacc atgtaatgcc tccgtttttt taagcaaatt tcaaggctaa tgaggcagca
    41401 ccaatgacac cagcttcatt accaagctct gctaatttga tttttgttga ttctcttact
    41461 tgcgggaaag taaattcttt aaaatatttc tctacacggc tacgtaaaaa ttctcctgct
    41521 gccgatactc ctccacctaa cacaatactt gacggattca atgtattccc caagttggcg
    41581 caagctaaac ctaagtagaa gcatacgcga tcaacaacca tcaatgcaaa cggatcgtct
    41641 tcttgagcca tttcaaagat atctttactt gttacttctt caccgttgtc taacattgct
    41701 ttcagttttg aatctcctgc gtattcttct gccaagtaac gacctagacg taccacacca
    41761 gtagcgctag acacagtttc taaacatccg cgtttaccgc aagtacattc gaacccttca
    41821 ggatccacag tgatatggcc gatctctccg cctgctccgc tcacgccgtg aatcaaattt
    41881 ccgccagcaa cgataccacc gccaacacct gttcctagag taacgaatac aacgtctgga
    41941 tcgttttctc cagcaccttt ccatcgttca cctaaagcag caacattcgc atcattatcg
    42001 atagcgaatt tgattcctgt tcctgcctcg atcagttttt tcacaaattg aacttctgtc
    42061 cagtttaagt tatacgcacc aataaccgtt ccagcttcgc tgtccacgct tcctggggta
    42121 cccatgccga ttccgataaa gtcttcggct ttcatattat ataaattcaa acgatggttg
    42181 attgattcaa tgatttcagg aacgatatgc ttaccatcat ccaaaatatt ggtatcgatg
    42241 ctccattttt gttgaatctc tccttctggt gttaaaattg caaattttgc tgttgttcca
    42301 cctaaatcaa tcccaataat cttcttgtcc attacaaatt tcctttcttt cggctttctt
    42361 caattcggtg ctctcttttt aatatgcgcc acgctgtcat gtatgtatca tgatcaatca
    42421 aacggctatc atacagatta cgcaattcga tagtcattaa ttcaatgtca tagatgcgtg
    42481 cacccacata gataaagatg ccaaattttt tgaacagctg ctgtacatca tataagctct
    42541 ccatctttaa gcacttcctt catattatac aagtaaacca tattttttta aacccagtaa
    42601 aatacatatt acaaaaagaa atacaaaaac tagtgtagaa agaatccttt ggtgtatcga
    42661 atagcttgtc tgttgtttcg gtagacccaa aacattccct aacactaatc cgccaattag
    42721 cccaccgaca tgtccccaaa catctacaga ggtatccaga agaccaaaaa caaatgtcaa
    42781 cacaataaat aaaagaaaat gtctgactag ctgctggatc gctgggttat gtttaaaatg
    42841 aaaccctaag ataaacaacg caccgaacaa accgaatatc gaagtactcg caccaccaga
    42901 cagaacattc gcttcgttaa aagcaaagct tgctgtattt cccattatcc cgctgaacat
    42961 ataaatcaag aaaaaacgcc aatggccata gattgcctcg atttgctgcc ccataaaata
    43021 cagtatcagt gagttcatta cgaaatgcat cagtccaaaa tggatgaaga ttggtgtcac
    43081 taaacgccac cattcattga agtgaacaag ataaggacca tacattccgg cataataagg
    43141 gatctcaagt cgcggaaata attccatcat gaggaagacc gctgtctgta tccctaaaaa
    43201 agcataggtc cataacggtc gtcttaacca tgcacgcaat tttatttgct gttgataatt
    43261 catgaaaacc tcccatttca ttttagtcaa taaacaattg ttggatcttc tgatcaaagc
    43321 tctccggttg ccattgttca ttcaattgtt cacgaaaaac aaggctacat gtttttttat
    43381 gaaaattatt taaataccgg tcgtaataac caccgccaaa accgattcga taaccggctc
    43441 tattgtagat aatacctggt acaatgagga gatcgatcat ctccggcaaa tagagcttct
    43501 ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag aacggactgt tcatccattt
    43561 cataaaacgc catctgacgt ttcggcaaag ttttaggtac aactattttc ttttgttctt
    43621 tttctgctcg ttggataacc ggctgtgtat ccagttcaaa ttcattcgat aaagtcgtcc
    43681 ctatcacttt tgctgacttc cagtactcgc tggcgaatag ctgtttatag attcgctgtt
    43741 ctttttcctt tttcttgcca cttttggcca gatttttcag cttttcgatt cctttccggc
    43801 gtaatcttac tttcaattgg tccaaaaact cacccttcct tctctcataa aatggtatag
    43861 gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc ataaatagaa taaaaagaag
    43921 acctagaaat gattggcctt ccttttttaa taaatttcaa ctgttcagcg cgtgtttttg
    43981 tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa agggcaatca aaattcctgt
    44041 aggtacttcc ccacttggta gaatcactct agcaaccata tctgcactaa gcagaaaaat
    44101 ggaaccgaac aaaccgctca gaacaaaggt ccagttattt tctttacgta cgactagctt
    44161 cgcagcatga ggagctagta gtcctacaaa agataaacta cctgtcaccg ctacactacc
    44221 gcttgccaaa gcaacagcta acaacaaaag gattttttga cttttagcca cgttaaggcc
    44281 taatccttgc gcgcgttctt gaccaaatga tagcaatcca atcctctgtg cataaagtcc
    44341 tcctagcgga attaagataa ccgcccatgg aagcaatgcc caaacataag gccagctcgc
    44401 accccagatt gatcccgcta accatgcatt cacaaatcca taattttcct tagataattg
    44461 gatcgtgcat agcaatgtta atgcagaaag gccggcatta acggcaatac cggacaataa
    44521 gattcgattc atacccaaaa agccatttcg atcataggcc gcaagataga cacagcaagc
    44581 agctaaaaca ccacctagaa aggctacaac tagcaataga aacggcagcg aatagtgcga
    44641 aaagaaacct aaataaagca tcactaaaaa tcctgctccg gcattaatgc ccaatatact
    44701 agaatctgcc aattcatttc ttgttactcc ttgcaagata taaccagaaa cgccaagaca
    44761 agctcctgct aataaactga tcagtaatcg aggaactcga aattctctaa caatcagcgc
    44821 caaagaagat gattctttcc ctatgaacgt ggcaaaaagc tgatccaggt aaataaaagg
    44881 cgtaccaatc attaaactac ctatagacag gatgacaagt acaaaaagca agaaatagaa
    44941 cgtccaatat atttttttca ccgttgttcc ctccttactt gtatcagtaa aaacggaacg
    45001 ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag ggggattgat catcctcgct
    45061 gtaaaatccg ccaacataac caatccaccg ccaactaaaa aagagacagg tagaacataa
    45121 cgatagtccg ttccaaccat tccgcgaaca actggcggaa ccaacagccc aataaatgaa
    45181 acaggtccga ctaacgaaac ggcaatggct gctaacactg caactagaca gaaaacaatc
    45241 aaccgcgttc gtttaggatg acttccaaga gctaatgcat gtgtttcact caaatgaatc
    45301 aaagatattg cttttcctaa tgaaaaagaa accaaaacag caagtatata taaaggaaac
    45361 aatactgcta attgtttcca tgtgatattg gcagctccgc ctacaaacca aaaagcaaga
    45421 tcctgctgca gattaaagaa ttgggtaagt gcttggctga tagcagtaaa aaaagaacta
    45481 atagctacgc cagctaaaat cagctgtaaa ggattcatgc ccattttcga aaactgcaaa
    45541 aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca atgacattag aaacacagaa
    45601 aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca ttgccaacga agcacccgcg
    45661 ttgattccta gtaagcctga atctgctaaa ggatttcttg tcactccttg catcaatgca
    45721 ccgctcaatg caaaacaact ccctacaaga aatgctcccg ccacacgagg caaacgaata
    45781 tttcgtatga tttggtgact ttgttttgat ctatcaaaat caaacaacgc ctgccaaaaa
    45841 tctgcttttc ccacagtcgc tgcgccattt gaaagagcaa caaaaaaaat aatcaaaaga
    45901 acaaaacaga ccaaaagcag gagtctattt ttcttcatag tcctcataat tgatcctcct
    45961 gctcttttgg caacaaatca taggttagaa aaactggttt atttgttctt ggaagcgtga
    46021 caatcgttgc atcaatctca aatatttttt tcatacactc ttttgtgatc acttcttcag
    46081 gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa taaataatct gaaaaacgtg
    46141 aagcatgatt aatgtcatga atcgacatca agatcgttgt ttgtttcatt tgattgattt
    46201 cagtcaataa ctgtaggatc tctaattggt gtgccggatc taaaaatgtt gtcggttcat
    46261 ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc gatccagaca cgctgggttt
    46321 gtccaccaga cagcgttgcg atatcccgca tacgaaatcc agctagacct gtagcatcca
    46381 acgcccactc gattgcttca tgatcttgcg tgtccatgcc actgaacagt ttttgataag
    46441 ggtatcgtcc gtaagatact acttcttcta ctgtcatacc tgtagggtgt tcactagttt
    46501 gtgctaataa tgtaattttt tttgcaagtt cttttgaact gtatgtagag atatcagagt
    46561 tattgacaat gatctttcct gatttcacag gtagtatacg ggtaaaactt ttcaataaag
    46621 tagattttcc acttccattt ggcccaatca aactagtgat tttcccttca ggaatcgtaa
    46681 cagacatgtt ttcaatgatt tttttgtttt cgtagccggc tgcaatgtca gctgctctta
    46741 atctcgtcat ttcacccatc ctttcgctga aaatcattct caattatgac gctgtttcaa
    46801 catttcgtca agcgctactt tcatatctat agccaaatga agcggttgac agcgttcgaa
    46861 atatcaggaa taataaccaa tgagaaagat tctcaattat gttaggagga aagaaatgaa
    46921 attaaaaaca aaagtattca cattatctag catattgctg ctggctggag tactgagcgc
    46981 ttgctccccc tcttcagata aagaaacagc tacaactgcc aattcgacga cttcatccaa
    47041 tagtactcat acagtcacag atacacttgg acataaagta gagattccaa acgcgcccaa
    47101 acggatcatc ggcagttact tagaagacta tctgattgca ctaggggaaa aacctatcgc
    47161 ccagtggact gttggcagtg gttccattca agattatctg caagatgatt taaaggatgt
    47221 cccaacgatt tcttatgacc ttccttatga gaaagtgtta agctttgagc ctgatttgct
    47281 gttgatttct tcttccgcta ctgtcgaagg cgggaaatac gaacaatata gcaaaatcgc
    47341 gccaacttat gttgtaaaaa acggaacaga tgtcacatgg gaagaacaac taaaagatgt
    47401 cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc atttccgatt atcaaaaatc
    47461 catcaagaaa actcgagaag aactagcaga taaaatcgag aacaagacag ctgcagtgtt
    47521 gtgggtgacc aacaactcag cctttatggt cagcaaaaat cggtcaagtg gaagaatcgt
    47581 atacgacgat ctggaatttg gtgttcctga tctagtggaa gaggtctcca aaaaagccac
    47641 ttctgactgg tctgctgttt cctctgaaaa gctagctgaa ttagatgctg actacatcat
    47701 ccttgtgaac agtgacaaag atgctgccat gttcaatgaa ccaagctgga agaatcttaa
    47761 agcagtgaca gacaatcatg tactgcaatt cggacctgaa tctagttggc tatataacgg
    47821 acctattgcc agtcaggaaa tggtcaatga tatcaaagaa aaactaaatt gattttaact
    47881 aaaaaaagaa tcttcacgat tagtcgtgag atgctttttt tcttattaac aaactagacg
    47941 catagatttt attcttcttt tgaagcaacc ctatttttta ctctttccca tttttgaaaa
    48001 cgatgggcat atagattttc ttgatccgtt atcccctcat actcctctat aagggcgaag
    48061 tctgaaaaat caatattccc aatatacgta tcgccttcaa acgtgctatc gatcaatgtt
    48121 cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa tccgactacc acccgaaaca
    48181 tagatatctt ctgagatcgt ttgactatac gacaaaagtt catcgatcga atgcattact
    48241 tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca acacgatgat atggcgataa
    48301 ggaagtgaaa gatcccccat tccttcatag gtctttcttc ccatcactaa aattcgatcc
    48361 attgtatgtt cgcgaaagaa acgcatatca tttggcaatc gccatggtaa caaaccattt
    48421 ttgccgatca gaccattttt atcttgtgcc cacatggaaa taaacatatt atccgctcct
    48481 tatgatttta gatgttttga gataaaaaaa gtctcaattc tttgaccagc aaggaattga
    48541 gaactttaaa aacattattt tgtttcacgg tgcaaagtaa ctttgcgttc gcgtgggcaa
    48601 tatttttgtt tttccaaacg atcaggattg ttacgtttgt ttttgcttgt tagatagtta
    48661 cgttctttac aagaagtaca ctctaaagtg atgtttacgc gcatgttttt ccctcccatt
    48721 tttacaagaa tcctctaaga tgactctcag acttgattat cttaccatga ttttttctag
    48781 attgctagtg tttttcacga ttttgttaag taaaactact tgacgataaa tacaacggtt
    48841 ttacttctca aacaaaatct ttttcttttt gtataaatac ccttacactt gtttatatag
    48901 attatgtttt ttaataaagg gggatactaa tatgccatgg aacatgaagg actttcctgc
    48961 atcaatgaaa aacttagata aattgacaag aaaaaaagca atcgacatcg caaatgcatt
    49021 attagatgaa gggtaccctg ataaccgtgc gatcccaatt gccattgatc aagcaaaaaa
    49081 atggtatgaa gatgctagtg aatcagaaaa acgaactttc gaaaaagaaa aaaatccaag
    49141 caagacggat gaacacgata cgaatcctcg tgctggaaaa ctgcttgatt cagatgtgat
    49201 cgtagaatat gaggaagaac aatggatcgt gaaatctaaa ggggcaaaaa aggcaagcaa
    49261 ccattttgat acaaaaaaag aagcaatcga aaaaggaaag caagtagcac aaaacaaaga
    49321 atcaactttg ttcatttata aaaaagatgg gacaaaagaa aaagaaatcg attattgaac
    49381 atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc cttatgttcg aaacaatggt
    49441 gttcctctgc caactccgaa ccataagtca taatatctat aaaacgggaa gagctgtttt
    49501 ttgaaattgt ttcttatcac tcagtgttaa acggtaggag aaaacctctt ttttattgat
    49561 atttgatttt catcaaacag tcacatagtc gattgcttct gcttgcggaa tcgtttcatc
    49621 tacaaagtag actttatacc atgtcaagaa actgaagatt gtccagattt ttctttgctc
    49681 ttctttacgt ccttcgtgat ggtcatctag caacttcatg attttttctt gatcaaaaaa
    49741 ttcttttgca aaatctgctt cgaataatgc tttgacttgt tcgtagccgt gttcttcttt
    49801 caaccaagct ttgattggca cagggaatcc taatttcaca cgattcgacc attcttccgg
    49861 aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg ttgttttgat tcaataaaaa
    49921 cttacttggt atttgttgag ccaatttcat gacttcgata tccaataaag gtactcggac
    49981 ttccaaagaa cttgccatag aaagtttatc tgcctttaac aagatatctt ttggcatcca
    50041 ttgatgaaga tcgacatatt gcatcttatt gacttcatct ttgattcctt ctgttttctc
    50101 gtaatgaaca gtcatgattt catccacaga tggtgctgtt tgatattttg gtgttaacac
    50161 ttctgatgct tctgattctt cgaacactcg agcatgaccg ataaaatatt cttttgcagg
    50221 agcaagtgat tcatataaat ggatccgtcc atggaaattt ttcatttttc cgattttacg
    50281 tcctaaatta tagcgtgttc cttttggtaa ttttttcaat ccttgagcaa tcacacggat
    50341 gaattttgaa ttcgtatgga atccatacgt ttggtatccc gcaaacagtt catccgcccc
    50401 ttctccagat tggactaccc gcacactttg tgaagcaaga tttgctaaaa agtacaaagg
    50461 tacgcaagaa ggatttgaat caggttcatc taagtgatac tggatcaaag ggaatgcttt
    50521 gaacgacatg tctccgtcga tcactgctgc tgtattatct aagtccaata gttcggttag
    50581 ttttctggct tcaatcgctt cattataggt tttatcatca aacccgattg agaaagaatg
    50641 atctggtttc aatacagagg ttacataact ggaatcaacc ccgctggata agaaagaacc
    50701 aacttctaca tcactgaccg tatgtgcttc aatagaagct tgaacggttt cgtcgatttt
    50761 ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca aaatctgcat cccaatattg
    50821 ctgaatgtct agttttccat ctttatacgt ataataatgg ccttcaggca aacgatagac
    50881 atctttgaag aatgtttcgc cgtttaatgg agaatattgg aaagtcatat aaggtttcaa
    50941 cgcttctttg ttcaattctt tgttaaaatc aggatgaggc agaaaacttt tgatttctga
    51001 accaaacata aatgttccgt tcatttctgc ataataatat ggtttgatcc caaagtggtc
    51061 tcttgcaccg aataactcat tcttttcatt atcccaaata gcaaaagcaa acattccgcg
    51121 gatcttttgc aataattctg ttccccattc ttcgtaacca tgcaaaagga cttctgtatc
    51181 tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct tctctcaaag gctggtaatt
    51241 atagatttcg ccattaaaaa taatgatctt tgtccgatct tcattgtaaa taggctgagt
    51301 accgccctct aagtcaataa tacttaatct tctgaatcct aaagcaacat gtttatcgat
    51361 atattctcct gaactattag gtccacggtg aacgattcga tccatcattg tattaataat
    51421 tgtttttttg ttgtccttgt cgttaacaaa acctacaata ccgcacattt aactttcaca
    51481 tcctaatata aaattactgt ttatttcatt catatgcatc ttatcataga ataaatagcg
    51541 gacgaatatt ttctctctta caatttcgtc acgtgaaaac aaaagatgaa agtttctgtt
    51601 tttacagaaa ataaagtccc aatatctaat ttaccatgtt ttcttttttg aggctacctt
    51661 attctcttcg tgttaaaaaa atattagtgg atgctatttc caaaaaaaac agcaaaaaaa
    51721 gacacgacct aaagatcgtg tctaattatg actgtatcag aaaatatgat accaaacgga
    51781 tctattcatt aattaattga catagtttat ctgttgctct tttatgactg gataactgac
    51841 caattcatga cgatccaagt cttctttatt tatatttaca gcagtaattt gactgtcttc
    51901 atacgtacga taataataaa tccctttatc aacgttacag caagaagaat aaatcgtata
    51961 ttcgtatttt ccttctccag tatcgcatac tcctttttgt tgctcgactg agcctagtat
    52021 atgaaaaaat tgactgatac tttcagattc tgaatcacct gatgcagcat tcattttagt
    52081 aaatgtggct tttacaaatc gagaaacaga agagagatct ccaggtaagc ccaatcctcc
    52141 catcccacga ctataaacat tcaagctgat ctggtttgaa aaatgatttt ctggtgttcc
    52201 atttgatagc gagcgataat tgttcagatt aaataattga taatcaaatg gcggattatt
    52261 tgtcaacaca ccgacaggat tatcatataa atgaagtcca tctttcatac tttcaattac
    52321 tatcgatttt tctttatcag ctaataacca gtgtaaaggt gacaagggta gtttttcact
    52381 aaaatcgata ttgactagat tgatagtagc caataattct ttagcttcgt ctatggttga
    52441 gcattgccct agtatccatg gaataaactc aaatggtgca acgttatctt ttccttcttg
    52501 taattcttta taatcagcat tgccaggaaa attcagtcct gccatactca accctttttc
    52561 atttgtagcc tcataataga gtggatagtt ggatacccca gctgctattc ctatcattgc
    52621 ataatgttta tctaaatttt ttacctttct aaaatcgaaa cgataatttc ttggagtaat
    52681 agtgactact tcattataag acatctcata atcaaaattc cttccaaaat aatggtcttt
    52741 cgttgcataa gtgattgcgg tacacatcgt tttccctcct aaaacaaatc gtttttacac
    52801 ttttatctta catctagtat ttttttttat caaaaaaaag gccaaagaag attgatttac
    52861 tagcatttat aaaaaatagt actcaggggg aatcaaaaaa tattgtaggt taaaagtaca
    52921 acaataaggg gctgtgacaa aagtcttgtc acagcccctt attccgaaca aacggtgttc
    52981 aaaagcttgc atctgcggta ataagcccaa ccaaacgaaa aaataggaaa agctattttt
    53041 gtttggccgt tcttattact tgatgcagga cagcttcttc acaacctcta atcgttgata
    53101 taaggaaggt acaggatttg aacctgcgcg ccggtattag ccggttcgcc ggatttcgag
    53161 tccggtgcat taccactctg ccaaccttcc gtaagtacta tttttaaact tttttcacga
    53221 aatgtcaagc ctatttctaa tagataaata acagaaatcg ctttttttag caaaaaagtc
    53281 cattgacagt ttgcagccaa cggacttacc gatcaaattc atactgatag aacactatct
    53341 gattatttca ggattatcta atgctaaaat cgagtcaatt gtccgtttga tcagtgcaat
    53401 gatttgttct tctgttggat gcatgatgtt tgatgacatc aatgacgcta agccagtcac
    53461 tgctacccat gtaccagtat gcagagcatc gacatattca tccgataatt gattgtatct
    53521 ttcatcttct ttaactattt cacggaaata attgtatgaa aaatcatgca ttttctttcc
    53581 gtccccatgt tcatcaatgt acaatgccat gtaaagacta tgatgctttt ttgcaaagta
    53641 gatatagttc aaaccgagat caatgatttt atcaccagta cgttcaatag ggaaaacatc
    53701 ttcttttagt tgttcaaaga tagaatccag caacgtattt tttaaatctt ccatgttttt
    53761 gaattccaga taaatcggct gtgtcgaaat ccccatcttt ttagcaatat ttctcgcagt
    53821 aaatccttta aacccttcct ttgcaacaac atcataagca gcttttagaa tttgatcctt
    53881 ggtatagact tttcttctca ttaaaactcc cccacttctt tactgcagta tatgttgttt
    53941 tattgtaccc tatttttagc attttttgca aacattttac tcaaaacgtt atattttaaa
    54001 tttttttcag tcttctttaa cttttttttg caaaattaaa aaaatttggt taaattcaat
    54061 gggttccctt acatttttag ttttgaccta aatgatagtt gtccaaatct ttcatttcaa
    54121 gttatagtta aagaaaatga aaaagaaggt gtgtaatgga aaacgaaact gacgttattt
    54181 atattcatcc tcaaaaacga atcgtttcac agaaaagaaa gtatttttat cttggtttta
    54241 caggtgtttt ttttcttttt attggcttgc tttctaatac tcctactgat aattggagtg
    54301 gattgctaac tattcttacc tcgccaagca atcttttgac agattatttt gctttaggtg
    54361 ttttcggaag cgcattcata aatgtaggga ttttgacctt actttctgtg cttttagctt
    54421 atcggcacaa ggtgatttta aacggtccct tatttgcttc gattctaaca gttaccggtt
    54481 tctctttttt tggcaaaaac ctttataatt ctatctcaat cattttaggt gtgtatctat
    54541 acgctgtatt tgtcaataaa cctttttctc agtacatcat gatcggactg tttggtagcg
    54601 tattatcacc ggtcgttagt tatatcactt ttggtatgcg ttttccttta ctgataggta
    54661 ttttattggg gaatttagct ggcatagcaa ttggtatact tcttccgccc ttagctgctc
    54721 aaactttagt tttccatcgt ggattcacac tttataatat tggattcacc tctgggttga
    54781 ttgcgatgac ttttactgct gttttgaggt tattcagcta ttcaatcgtc gaaaatacat
    54841 tggttttcaa tgaatatcac tttcctctca tttggattat ttttggcttt ttttcgctga
    54901 cagtcggaat tggtttctat tataattcct ttcggctttc ggggattcga gaaattttcg
    54961 attcatctgg aaaattgaca actgatttca ttgctaattc tggtattggt gctactttga
    55021 tcaacatggg cttagttggt ctgatgctgt cttcttatgt tttgctggtt ggcggtcagt
    55081 taaatggacc tgtcatcggt gctattttat ctgcggtggg tttcagtgct tttggttgtc
    55141 atttaaaaaa cagttttccg atactagtcg gaatatttat tgcttctttg tttggaactt
    55201 ttcatgagat caccagtact ggcatgcttg ttgcagctgt gtttgggaca ggtcttgcgc
    55261 ccataagcgg tttttacggc agtttttacg gtgtaatagc tggtgtgcta catattgctc
    55321 ttgtccataa cgtcagcact ttgcacggag gactaaatct atataacagt ggtttttcaa
    55381 ctggtttcgt tgcaggtatc cttgtaccga tactagataa ctttaccgct gtcagaaagg
    55441 aaaaaaagac acttggaaaa agaattatca aaaagaatca tcgatgagct tcttacttat
    55501 ttatattccc atgaaataac tgaaatacgt attggagtag aatttgctga ggaagggctt
    55561 ttcatagaga tacagggtac ggcagaaact cagccagaag atttagatgt acttgctgat
    55621 ttgctgaaca atcctcggga ccctagtatg gaaatctact atcaagaact attaggtaat
    55681 ccccgacatg atcgggaaga ttatcatctg ttaggtagtt tgattgatga cgtggaaatc
    55741 atgtatgccc agccgattat caatattaag atctttcgac gtgcttctca ttcctattat
    55801 taaccctatt ttctatttat aaaagactga atcaaaaaag cagctcctga aagttcgatt
    55861 aaaatctact ttcaggagct gttcaagctt gacattattg attttccaat ccttcataca
    55921 cttcatctgt tacaggttct aaaaactctg aattaccagc agtgatcgcc aaatgttcaa
    55981 accaactgtc ttttgtcgca ccatgccaat gtttaatccc tttgtgcgtt acgacgacat
    56041 ctccagccat taatcgtctt gctggctttc cttcttcctg ataccagcct tctcctccgg
    56101 tcacaagtaa gatttgatag ccgtctgtat ggacatgcca gtgattgcga caacctggtt
    56161 caaaagttac attacctaca ccaacagaaa cttcgggatc attcactaac atattcagat
    56221 agctttgccc ggtaaatact tgagcgtaag cttcgttttt ttcacctgct ggaaaaatca
    56281 cgccattgtg tatttcttcg tgttttgtca tcatttacgc ctctttctta tcttcgctat
    56341 tttcttctaa atagatttct tttgctaaac taaaagctga ccaagctttt ggccattcta
    56401 cataaaaagc taaatgggta atgatttctg ctatttcttc actagtaatg ccattttgct
    56461 tgccaatctt cagatgagct ggcaattgtt caaaatttcc tcctgaaatt aatgcagata
    56521 tggtgatgat actacgctga tgagcagata attcttctct ggaccatact tgtccaaata
    56581 aaacatcatc atttaattct gcaaattttg gtgcaaaatc tcctaattga tctcgtcctg
    56641 cggtttgttt ttctgccatt tctcttattc tcccttcacg actgttaggt gattcaacta
    56701 tggttctaag gcaactttat tttctattgt ttcttcgcat ttcattttaa atgtagtctt
    56761 tcagcctgtc caatgcttag tttattcagt cgatatgctt tttaagcata gttgctaacg
    56821 ctttttttat tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga
    56881 gatcaatctt ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa
    56941 aatggcgcag ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt
    57001 gatgaataat gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat
    57061 taggcctatc aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga
    57121 atgcgttaag aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca
    57181 tccaaatcct gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg
    57241 tcctgatatt tggcccttat gctggattta tctataacta tattggaatc tgcattggtt
    57301 cgattatcat ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta
    57361 gcgataagac atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc
    57421 tgtttgctct agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg
    57481 gattgacaaa catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt
    57541 cgattttctt atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg
    57601 gataatattt attttgtaaa attagtcatt gattgacaat gt
//
LOCUS       DAPBBR010000013        56803 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPBBR010000013 DAPBBR010000000
VERSION     DAPBBR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.013"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            101..571
                     /locus_tag="RD488_000807"
     CDS             101..571
                     /locus_tag="RD488_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HDT7656903.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            793..1896
                     /locus_tag="RD488_000808"
     CDS             793..1896
                     /locus_tag="RD488_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7656904.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            2117..3076
                     /locus_tag="RD488_000809"
     CDS             2117..3076
                     /locus_tag="RD488_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7656905.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            3246..3926
                     /locus_tag="RD488_000810"
     CDS             3246..3926
                     /locus_tag="RD488_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7656906.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            4016..5050
                     /locus_tag="RD488_000811"
     CDS             4016..5050
                     /locus_tag="RD488_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7656907.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            5064..5399
                     /locus_tag="RD488_000812"
     CDS             5064..5399
                     /locus_tag="RD488_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656908.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            5383..7863
                     /locus_tag="RD488_000813"
     CDS             5383..7863
                     /locus_tag="RD488_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656909.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            7919..9478
                     /locus_tag="RD488_000814"
     CDS             7919..9478
                     /locus_tag="RD488_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7656910.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            9475..10839
                     /locus_tag="RD488_000815"
     CDS             9475..10839
                     /locus_tag="RD488_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7656911.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            11010..12080
                     /locus_tag="RD488_000816"
     CDS             11010..12080
                     /locus_tag="RD488_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656912.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            12095..12763
                     /locus_tag="RD488_000817"
     CDS             12095..12763
                     /locus_tag="RD488_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656913.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            12783..13361
                     /locus_tag="RD488_000818"
     CDS             12783..13361
                     /locus_tag="RD488_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7656914.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            13762..14673
                     /locus_tag="RD488_000819"
     CDS             13762..14673
                     /locus_tag="RD488_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7656915.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(15051..15968)
                     /locus_tag="RD488_000820"
     CDS             complement(15051..15968)
                     /locus_tag="RD488_000820"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDT7656916.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            16170..16607
                     /gene="zapA"
                     /locus_tag="RD488_000821"
     CDS             16170..16607
                     /gene="zapA"
                     /locus_tag="RD488_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDT7656917.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            16665..17213
                     /locus_tag="RD488_000822"
     CDS             16665..17213
                     /locus_tag="RD488_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDT7656918.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            17328..19688
                     /locus_tag="RD488_000823"
     CDS             17328..19688
                     /locus_tag="RD488_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDT7656919.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            19775..20089
                     /gene="trxA"
                     /locus_tag="RD488_000824"
     CDS             19775..20089
                     /gene="trxA"
                     /locus_tag="RD488_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDT7656920.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            20271..22049
                     /gene="uvrC"
                     /locus_tag="RD488_000825"
     CDS             20271..22049
                     /gene="uvrC"
                     /locus_tag="RD488_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDT7656921.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            22194..23093
                     /locus_tag="RD488_000826"
     CDS             22194..23093
                     /locus_tag="RD488_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656922.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            23086..24348
                     /locus_tag="RD488_000827"
     CDS             23086..24348
                     /locus_tag="RD488_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656923.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            24509..26407
                     /locus_tag="RD488_000828"
     CDS             24509..26407
                     /locus_tag="RD488_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDT7656924.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(26737..27456)
                     /locus_tag="RD488_000829"
     CDS             complement(26737..27456)
                     /locus_tag="RD488_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDT7656925.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            27793..28125
                     /locus_tag="RD488_000830"
     CDS             27793..28125
                     /locus_tag="RD488_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656926.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            28112..30115
                     /locus_tag="RD488_000831"
     CDS             28112..30115
                     /locus_tag="RD488_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDT7656927.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            30134..30604
                     /locus_tag="RD488_000832"
     CDS             30134..30604
                     /locus_tag="RD488_000832"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDT7656928.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            30625..31209
                     /locus_tag="RD488_000833"
     CDS             30625..31209
                     /locus_tag="RD488_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HDT7656929.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            31224..32210
                     /locus_tag="RD488_000834"
     CDS             31224..32210
                     /locus_tag="RD488_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HDT7656930.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            32200..32511
                     /locus_tag="RD488_000835"
     CDS             32200..32511
                     /locus_tag="RD488_000835"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDT7656931.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            32533..34314
                     /locus_tag="RD488_000836"
     CDS             32533..34314
                     /locus_tag="RD488_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDT7656932.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            34307..35683
                     /locus_tag="RD488_000837"
     CDS             34307..35683
                     /locus_tag="RD488_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDT7656933.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            35690..36325
                     /locus_tag="RD488_000838"
     CDS             35690..36325
                     /locus_tag="RD488_000838"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDT7656934.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            36355..37710
                     /locus_tag="RD488_000839"
     CDS             36355..37710
                     /locus_tag="RD488_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDT7656935.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(37902..39296)
                     /locus_tag="RD488_000840"
     CDS             complement(37902..39296)
                     /locus_tag="RD488_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7656936.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            39388..40359
                     /locus_tag="RD488_000841"
     CDS             39388..40359
                     /locus_tag="RD488_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDT7656937.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            40356..41138
                     /locus_tag="RD488_000842"
     CDS             40356..41138
                     /locus_tag="RD488_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDT7656938.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(41307..41678)
                     /locus_tag="RD488_000843"
     CDS             complement(41307..41678)
                     /locus_tag="RD488_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7656939.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            41812..42255
                     /locus_tag="RD488_000844"
     CDS             41812..42255
                     /locus_tag="RD488_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDT7656940.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(42298..43107)
                     /gene="yidA"
                     /locus_tag="RD488_000845"
     CDS             complement(42298..43107)
                     /gene="yidA"
                     /locus_tag="RD488_000845"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDT7656941.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(43126..44493)
                     /locus_tag="RD488_000846"
     CDS             complement(43126..44493)
                     /locus_tag="RD488_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7656942.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(44477..45307)
                     /locus_tag="RD488_000847"
     CDS             complement(44477..45307)
                     /locus_tag="RD488_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDT7656943.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            45470..45907
                     /locus_tag="RD488_000848"
     CDS             45470..45907
                     /locus_tag="RD488_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDT7656944.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            45983..46603
                     /locus_tag="RD488_000849"
     CDS             45983..46603
                     /locus_tag="RD488_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDT7656945.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            46792..47298
                     /locus_tag="RD488_000850"
     CDS             46792..47298
                     /locus_tag="RD488_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDT7656946.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            47315..48214
                     /locus_tag="RD488_000851"
     CDS             47315..48214
                     /locus_tag="RD488_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDT7656947.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            48301..49185
                     /locus_tag="RD488_000852"
     CDS             48301..49185
                     /locus_tag="RD488_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7656948.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(49377..49448)
                     /locus_tag="RD488_000853"
     tRNA            complement(49377..49448)
                     /locus_tag="RD488_000853"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(49413..49415),aa:Arg,seq:ccg)
     gene            49508..50842
                     /gene="rpoN"
                     /locus_tag="RD488_000854"
     CDS             49508..50842
                     /gene="rpoN"
                     /locus_tag="RD488_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDT7656949.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            50991..52082
                     /locus_tag="RD488_000855"
     CDS             50991..52082
                     /locus_tag="RD488_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HDT7656950.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            52123..53124
                     /gene="gap"
                     /locus_tag="RD488_000856"
     CDS             52123..53124
                     /gene="gap"
                     /locus_tag="RD488_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7656951.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            53234..54424
                     /locus_tag="RD488_000857"
     CDS             53234..54424
                     /locus_tag="RD488_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDT7656952.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            54528..55283
                     /locus_tag="RD488_000858"
     CDS             54528..55283
                     /locus_tag="RD488_000858"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDT7656953.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            55399..56697
                     /gene="eno"
                     /locus_tag="RD488_000859"
     CDS             55399..56697
                     /gene="eno"
                     /locus_tag="RD488_000859"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDT7656954.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        18899 a         9877 c        12009 g        16018 t
ORIGIN      
        1 agaatctctg aagaataaat cacgtgatcg tgacgataaa atacacttac gtcaggtgat
       61 aaaaaataca taagtagaaa actaagagga ggaacagaaa atgaaagaag ttcaattgat
      121 cagaaaaagc gaactatcag aaggtggttg caatgcatgc ggcgtagtag aagcaacaag
      181 ctatacatta aagcttggtg ccaacaaagc gataatctct gagttgacag taggcggtct
      241 tgtggacagt ctggcgcttg ctgaaggttt tattggagaa gatatttatg agatgttttc
      301 agaaatccgt cagttaaaaa aaggggaaaa ctgcatagag gttcatcatg agagcccgaa
      361 tgtgagattc aaacgtggtg ataatgagat gatcttcaat aatcatgtgt ccgatcacac
      421 cgagctatat ggaatcgtga atcaaatact aactgagctt tttggattgg gaccttatgc
      481 gttcaaggaa gaaaacggta atccaaaatt aaacgaagaa tggcaagaaa cgattgaaat
      541 acaaagaaac aacccgcact tatttcaata ggcatccaca gtatttcgta aaagggactt
      601 tgacacgact tttgtcaaaa tcccatcgtt ttttatctat ttgtgttcta aacatttctt
      661 tcagagtagt aacaactgga atgactgaaa tgtaaacaga ttatttgcct gtatcaatac
      721 ggaagagtaa tataaagtgt gtaaacgcta tcatattatt cattcaattt tttatagagg
      781 gaaggcattg aaatggaaaa aacgtatcaa gcaggtacaa atgaaggaat agtggatttt
      841 atcaatatgg aagatttaga aatagccgct tcacaagtga ttccagctgg tggttatggt
      901 tacatcagca gtggtgctgg cgacttattt acttatcaag aaaatgaacg ggcattcaat
      961 catcagctga ttattcctca tgtattaaga gatgtagaat tacccgatac aactacacat
     1021 tttgacaaag aaacgctgac tgcaccaatc atcatggcac cagttgctgc tcatggctta
     1081 gctcatgtga aggcggagaa agcttctgca aaaggtgtag cagattttgg gacgatctat
     1141 acagcaagtt cttacgcttc ttgtacatta gaagagataa gagaagcagg cggggagaaa
     1201 gcaccgcaat ggtttcaatt ttatatgagc aaagatgatg ggatcaattt ggatattctt
     1261 gaagtggcca agcgtaatgg agcaaaagca atcgtattga cagcggatgc aacagttggc
     1321 ggaaaccgtg aaacagaccg cagaaatggg tttaccttcc cactgccaat gccgatcgtt
     1381 caggcttatc aatcaggagt aggccaaacg atggatgctg tgtacaaatc ttccaaacag
     1441 aagcttagtc caaaagatgt agaatttatt gctgctcatt ctgatttgcc agtctatgtg
     1501 aaaggtgtcc agtcagaaga agatgtctat cgttcattag aatctggtgc tggcggaatc
     1561 tgggtatcta atcatggtgg ccgtcaacta gatggtggtc cagcagcgtt tgattcgttg
     1621 caatatgtgg cagaagcagt agataaacgt gtaccaatcg tgtttgacag cggtgtacga
     1681 cgcggacagc atgttttcaa agcaatcgca tcaggtgcag atcttgttgc tattggcaga
     1741 cccgttattt atggattgtc tttaggagga agtacaggag tccatcaagt gtttgatttc
     1801 tttaaaacag aattggaaat ggtcatgcaa ttagctggaa cacaaacagt agaagatatc
     1861 aaaaaaataa aattgcgtga gaatcgtttt atttaagaaa caaatgacga aaaaaatagg
     1921 agtgcggcag atgatgccgt actcctattt ttatagttca aggatgtcac taatagaata
     1981 atttgaaacg aaaaaataaa attgaaatat tttttcatac ttcgccgatt gtaaaattaa
     2041 gctagacaac taaaaaaagt catttgtgct acactcaaaa tagttccgac gaaagaatta
     2101 taaggagtga gtacaaatga cctataacca tcttacacca actgaactcg taatgataga
     2161 agcttatttc aatcaatcac aacctgtttc aaaagtagcc aatctgttac aacgttctcg
     2221 acaaactatt tataaggtct atcgttttct taaatctggt ggaagcgcaa tgagctacta
     2281 taaacaatat aagaaaaaca aacgtaactg cggaagacat ccgattgttt tacctgatga
     2341 gcaacaggaa tacattcaaa aaaaggttgt tcaagggtgg gctcctgatg tccttattgg
     2401 tcgagcagag tttcctattg cttgttcggt acgcacactg tatcgaatgt ttaaagataa
     2461 aacctttgac actcacgatt taccaatgaa gggaaaaaga aaaccaaacg gtcataaaga
     2521 aaaaagagga aaacaagggt ttcgccggtc aatccgagac agaaagacag actataccca
     2581 gtttgatcat gaatttggtc acctggaagg tgacactatc gtgggtggaa aacataaaag
     2641 cgcggtcatc acattagttg aacggctatc taaagtcatc attaccttga aacccgaagg
     2701 cagacaggct aaagacattg aaaataggct gaatcaatgg tttcgttgtg tcccaaaaaa
     2761 cttatttaaa tccatcacat ttgattgtgg aaaagaattc tcaaattgga aaaagattag
     2821 taataccaac gatatttcaa tttattttgc ggatccagga acaccttctc aacgaggatt
     2881 gaatgaacat tcaaatggct tattacgtaa agatggtttg tataaagcta tggattttaa
     2941 tggtgtatct gaaaccttta tccaatcggt ggcatcgaaa cgaaatcata ttcctagaaa
     3001 atcattacac tatcggacac caatggaagt atttttgagt tacgtcacaa aagatgattt
     3061 gtctaactta atttgacaaa cgaaacttaa taaaaaagga agaatattca tgtaaacgat
     3121 tttattgttt ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt
     3181 catgaggatt ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat
     3241 ttattatgaa aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct
     3301 tggcaacacc agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg
     3361 aaccaacaaa taccgtggag cctcttaacc ctactgatcc ttcaaaacca gtagagccag
     3421 cagatccgga aaatccagca actggccaga caggtccttt aacactggat gtagttcccg
     3481 aattgccatt tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt
     3541 caaaaaacga tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc
     3601 aagcacaagg gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt
     3661 tgcaaggcgc tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat
     3721 ccactggacc aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa
     3781 tatttacagc agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa
     3841 atatcacact gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga
     3901 acctcgtggc tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa
     3961 tactataggt gaaggatttt ttaccgcagt tgttgttgaa aggatgtggt ggacaatgaa
     4021 tcaaagtaaa cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc
     4081 gtcaatcagc caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga
     4141 gaaccaaata gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca
     4201 gacactagaa gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt
     4261 caatccggcg gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt
     4321 agatgagaca ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa
     4381 tgtatcagca catgcagaaa caactgtacc tatagaagtg aaaatcccag caaaaagctt
     4441 taagggacgt gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa
     4501 tgctacagaa ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca
     4561 agaaagtcaa gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt
     4621 caacgcaaag ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa
     4681 tttgatattt acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa
     4741 tgcattttta gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa
     4801 agcaaaagcc ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg
     4861 gcgatttaca caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc
     4921 cgtttttgca gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt
     4981 tctagtgtta tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga
     5041 aacaacatga tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa
     5101 gtttgctgtt cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga
     5161 ttacatttta tgatctaagt ccaattccgc atccaagtgg ttcagtcaat ggcgcatcaa
     5221 aacagcagac acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga
     5281 cgaatgaaca aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg
     5341 cgtggttgtt gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa
     5401 ttttcatttt ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt
     5461 tcaccttcgg cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg
     5521 tatgaaaata tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc
     5581 caactaactg gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca
     5641 aatgatcctt ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca
     5701 aatgtacttg atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat
     5761 ttgccggaac atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac
     5821 ttgtatattg ccggtgcccc catcaaggtt actagcggaa gtttattatc agcaggaagc
     5881 cataccttgc gttttgggat ggggtcgtgg gatacaaata ctctattgac agatattatt
     5941 gctattatta cgcgaggcga attcaacgtg gacgatatcc cgcttcaatt tgatgttaca
     6001 gctaatgtcg cgaagatgac agaaaacgga gataaatatg atacgagtcc aaacaaaatt
     6061 ttgaccaagg gtaaattaca accttctatg tctaaaaagg ccgttttttc tgttgatttt
     6121 tatgattcga ataatattat ccaagatcgt atgttcaatt cgattttagc tccagctgca
     6181 ggtagatttt atcctaaatt aactggcgga aacttgaatc caggagcata tgcattttct
     6241 gcaagtgcag agataaatac gtggaatagt tacatctcac caagtgattc aacaggaaaa
     6301 tataatacat ttgctgatac cacagaatac gtggatggaa ataaccagaa ccttccaggc
     6361 tctaccaata gtcggacatt gacgatgggg ctgactgaag gacgttttga tcagttgcca
     6421 tttagtcgct ttgatcgcgt agtcaactat tttacaggaa aaaacgttac acaaggagca
     6481 atactgactc atactccagc aagcacaagt ggattgaatc agacagccaa tatcgtgtac
     6541 agtgggaaag atgcgcaagg cggattgctt tctcctgttg ctttaaaggt attggagcag
     6601 tacaagctag acggaacggt tttaccaaca aacttaacag ccgatagtca gtggggaaag
     6661 ctcctttctt ctgcatcgta ccaagtcacg gccaattggt cagcaactga actaaaaaag
     6721 ggttcgatcc attacaggct ttattcgaaa ggaacccaaa aattagcgac aggatggaca
     6781 gatcaacttt tccaaacgat ccaatcaaat aacgggggtg taaatacagc tacttctaca
     6841 ctacctgcat tggcttcagg gcaatattat tttgattatc gcttggtgga cgatgtactt
     6901 actaacatgt atccgtcttt tgcgtacaaa tggcagtctg aacaagctgg aatcaccact
     6961 cttcctcaaa taacagtggc taattttcca tctgtgagtg cagatagtca gctaaaaaac
     7021 cttagcagac aacctgagac aggagatccc ctgtctgctc tatcaggaga tacgattcaa
     7081 gaaaatgtga cattcacgtt aacaaaatct ggggatgcga taaccgacaa aaaaatcacg
     7141 atctcacttc ctgaaaatac tacttatatc aatggttcct taaaattaaa tggtacaact
     7201 atcgcagata ccggcattca acaaggagtt tctgtcccag cagatctatt gagcaaaata
     7261 ggagatacca ttcatcttac ttacaactat caattaaata ctgtagatac ttctttacaa
     7321 tccgtcagca tactgacaaa ggcagctgta ctttccagca atattacatt agcagatggt
     7381 gctaagcttc ctaacccagt tgtccaaaca tctgctaaaa caattcttgt ccccaaacaa
     7441 gaattaacat tagttaatgt accagatgat tttacatttg gtaacgatct ccccaaaccg
     7501 ttgaagacaa gttattatga atcaaaaggc gatttttctt ttgatgtgcg ggatactcgg
     7561 cttccaagca cgtctccttg gcaactgaca ggtacattga cttctttatt taagaatgat
     7621 caaggtcaag aattaagcgg aacaaaatta tacttcaatc attctggatc aaagcaattg
     7681 attcagcaag gtcaaaacac gttgatttat gagagtgatg gaacagctaa aggagaggtt
     7741 ctcgttgact ttcccgatac cgatggttta ctcttagagg taaatagcag tacgaatgct
     7801 caacctggcg caacgtatca aggcatggtc acatgggaac tgacagctgg gccaaccagc
     7861 taagtgatta gaatttgtat ggatctgtga taactgtcac agatcctctt tttcaaggat
     7921 gagaaggaaa cttctgctgt taaaatcaga aatgcttgaa ggagtggact tggaactttt
     7981 cagtttgctt gaaaaaaatg aacaacggca aatcaaactt ttccaacttt tattagagga
     8041 aaaaggagag gtttccgtta ataacgtact tacccgctta tcagttgatc gggctacctt
     8101 gaaagaagat ctgttttatt tacaagctaa cttggaaaat atcaaacaat tggaaattgt
     8161 tatccaagaa gggaatattt tattaatcag acatggaaat atagcagcag tcgatgttta
     8221 ttatcattgt tacttgcgct attctacaaa atatcagata cttctttatc tgttggaaaa
     8281 tggctcattt gatcggcaga aacttgtcat ggaacttaat atcagttcgg ctactttgtc
     8341 tcgcagagtg aaggaattaa atgattcttt aaatgagttt catctgaaaa taaaaagcgg
     8401 gcggctgacc ggtccagaaa gtcaaattcg ttatttttat ttccaattat tttggtttgg
     8461 acgtccctat cttgaaaaca aaaaagaata cagtgattta tcaggaaaca cttttttaga
     8521 tctgctgcaa aaagagttta gttttgctat tacagaagaa ggacgattga aatttgaaat
     8581 atggctttcc attatgaaga agcgaatgcg ctgtacgaaa aaatccaaac cagattatag
     8641 caatcttcct gttggattgt ttcaaacgac acaattttta ttggacctcc atacattttt
     8701 gacccgttac ttctttcaat atgcctttcc ttggaatcaa aatgaaacgt tggtttttta
     8761 tcttttcatg atcagtaact ttacattaga tacacataac tcgcatgtcc aggagttttt
     8821 gataagcgaa aaatacaaag acgacgtagt agctcaattg aatcgaacgt ttaaacaatc
     8881 gatagaagaa tatttctctt tttatgtttt tccagaagag atttcgcaaa agattgcgtt
     8941 gacagtgatg caaaatcacg ctcattttgc ctattttaga ggatggatga atatttttgg
     9001 ccaagaagga ttaaaacagc ggttaactga agtagaagat aaacaattcc tggttttatg
     9061 tgaaagattg gtcagacaaa catttgctat tgttgatttt actgaagtag acgaggaaaa
     9121 tgcccgcttt gaattatttg ctcgctatgc atctatttta cggacgctga tcaagcagtt
     9181 agaattacgt ctgcaaattg cttatgatct tccttatgaa aggctaatgg cggatatcgt
     9241 gaaagaaatc atccaggaac aattgctgaa tacgatcaaa tatgatttag tcgaatacga
     9301 gaaagaaaag cagtatgata tcattttgac tagccaattg aaagagtacc cgtcacagaa
     9361 gtccgctaaa gtttttgtat tcactagcaa cgaatataat tatgatttcc cctatttgaa
     9421 ccaattttta aaagaatgtt atttagaaaa attgaattta aggatgaata aaacatgaaa
     9481 atcgtgatca ttggtgcttc ccatgaaggc atcacagctg ccctaaatct aagaaaactt
     9541 caaccgaaag cagaagtttt actgatcgat gaagatcata aagatggact aggctatgtt
     9601 tcaaatggaa tcaaccttta tttaaaagga aagatacgta gtttagctga agttgcccat
     9661 aacatgcgga ctcttcaaga aagtggggca aaactgatca ccgaatggag agtaactgaa
     9721 cttgatccag acaaacatca gctcatcctc gcatccaaag aaggaaaaaa cgagaccata
     9781 acctatgata aattaatcgt agcgacaggt tcctctcctg tcaccttgta taaacaaatt
     9841 gaagctgaaa atgtctacac ctataaaaat ctagtgcaat ctaagcaagt acttgccgct
     9901 ttaaaagaag caaaagaagt agtgatcttc ggtgctggtt acattggatt ggaattagca
     9961 gatgctttga gaaataaagg atacattatt catctagttg attatatgcc gaatgtttta
    10021 tcaagatatt tcgataagga tatgatcaac agttttcaaa atcagctgca aactaagcaa
    10081 ataaattttt atccaaatga attcttgatc gattggaaaa aatcagaaga gaaagtagta
    10141 tccgtacaac ttctgtctca aacaataaag gcagatatgg tcattttttc tgcccaaact
    10201 cgtcctaata cgacattgtt aaaagaaaaa gtggctttgt atgaggatga gactgtgata
    10261 gtcaatgaat atctgcagac aagtgatccg gacatctatg cgattggaga tatcgtccca
    10321 gtcagttttg acaaaaataa acggcatctc tttttacctt tagttactcg agctgtacat
    10381 atggcaagag cagtagcgct aactttgagt ggtcagccaa ccgcttacga cctcagacaa
    10441 aagataacag cagcagtcat tatagactac tttttaggaa ctgtagggct gacagaagat
    10501 gaagcgccat tcttggaaca aaataccggt tcgtgttcag gagaatttga tctatttcca
    10561 caatacgacg aagaaaacaa aacagtaaat gcaaagctga tctaccatcc ggatacatta
    10621 gaaataattg gcggacagct gataagccaa gaattcttat tatcagattt gaacctgctt
    10681 gcggatatcg tgaaacacaa aactacgatt ccacagctag cagttgagga ttttggattt
    10741 ctgtctgaat acacctctcg ttttcactac ctcaatgagt tagcttttaa agtactagct
    10801 aagagagcaa atagcaatag agtagataaa agactgtgag aaatatcacg gtcttttatt
    10861 gtgtggggat ataataaata ttaatcaatc gagaataaaa aattcatata atgaaatagc
    10921 ggaagaattt tttgagcata atattcgcca aaaatttatc aagtgataaa attgttgtat
    10981 aaaatgatta tttcaggagg aggagttaaa tgtttttagc attaaatgaa attatgcatt
    11041 caaagttacg ttatgcgtta gttgcagggg tgatgttttt gatcgcctac ctggtatttt
    11101 ttttgactgg gttagcttat ggcttagctc aagataatcg aacagcagtc gacaagtggg
    11161 aggcagattc gattgtgctt tcgaaagatg caaattcaaa tctagggatg tccatgatta
    11221 ctaagaagat agcagaagaa gtcgaaggtg ggaaagtggc gtatcttgcc caaacacctg
    11281 gagtcgtgac tagtaaagac agtacagaag aaggaaaaat caatgttagc ttcttcggta
    11341 tcgataaaaa tcaattcatc atgcccaatc ttgttgaagg aaaagctttt gataacgatg
    11401 atgaggcagt aggcgatatt agtttgaaag aagaatatgg tctagccata ggagatacag
    11461 ttaagttatc tggtagtgac aagacgttta aactaactgg ctttacggat catgccaaat
    11521 tcaatgtctc accagttctc tatacaacca tcaatgctta ccaagaaatc cgcttcgaaa
    11581 aagaagatac aagtgaaaat gcacggatta acgcaatagt tgtcagaggt aaaatcagta
    11641 atttacctga agatttagaa cagatcaaaa tttctaaatt catcaatgaa ttacctggat
    11701 ataatgcgca agtattgact tttggattta tgatcggatt tttgatcgtt attgcggcta
    11761 ttgtgatcgg gattttcatt tatgtactga cgatgcaaaa gattaatatc tttggtgtaa
    11821 tgaaagcaca agggatcaca ggaggattta ttgcgcgttc tgtagtggca caaacattca
    11881 ttttatcatt tgttggtatt cttcttggtc tattaggaac agtgggaaca tcccttgttc
    11941 tacctgatgc ggttccattc caaagcaatt ggctgttttt tggcgtcatt agcttgttga
    12001 tgttagtagt agctgtgtta ggcgcactat tttctgttcg gacaatcgta aaaatcgatc
    12061 cgttgaaggc aattggataa gaaggaggaa gaacatgaaa gcaatagaat ttaaagaagt
    12121 agaaaaaagt ttccaagatg gcgaccaagt agttaaagca ttgaaagaaa caaccatgag
    12181 tatcgataaa ggggaatttg ttgcaatcat cggtccttct ggttcaggta aaagtacttt
    12241 tttgactttg gcaggcggat tgcagacgcc tagcagtggc tctgtattta tcaatgatca
    12301 agaattcagt aatcaaaaag aaagcgaacg cgttaaacta cgttttaaag aaattggctt
    12361 tattttgcaa gcttccaatc tggttccttt tctgacagta aaaaagcagt tattattagt
    12421 agataagatt aaacatgaac atcgtcaaaa agaagcaaac gaattatttg agcagcttgg
    12481 cgtggataag ttgatcaaca agtatccaga agaactatct ggtggagaac ggcaaagggt
    12541 cgcaatcgct cgtgcattgt acaatgatcc gtccattatt ctagcagatg aaccaactgc
    12601 tagtttggat tcagaaaagg cacgagaagt agtcgatatc ttggcaaaag aatcaaaaga
    12661 caaaaataaa gcaacgatca tggttactca cgatacacgg ctgattgaca aatgcgatag
    12721 aatatttatg atggaagatg gtgtattgaa agaaaaagaa taaccaaaaa gcaggtggaa
    12781 aaatggtcca tcgatacaac aaagatacac agcaaaaaat tttgaaagaa gcgactgact
    12841 tgtttatgtc caagggatat ctcggcactt caacaagaga aatcgcacaa aaagttggga
    12901 tcacccagcc caatctctat cattatttcg gtgataaaga aaaactatat acggcagttt
    12961 tagaaaacca cttaaaagat gttggaaaag ctttgagaga aatcgttcaa acaagcgaaa
    13021 cgggatttca agtaaccttg acaaaaatgg cgcagttttt gattgagaca catctggtcg
    13081 atttgtttct gatgcttcac gatcttgaaa gcaatctttc aaaggaaaca agagatcatc
    13141 ttttctttct atggaagaaa aattatcgtg aaccttttga agaaatcttt tcagcaaacc
    13201 aatctgtgct aagaaatggg atttcaaaag aaatcgcagc aaggcatttt ttcttagtgt
    13261 tagcacctta catcactcgg tcgaaaagac ctgtggaaga accgctaaat gtggcgcaat
    13321 tgatcgattt atatttgaat ggtgtattag gagaagcgta aagctgttat atagggagaa
    13381 aatagttagg tgaagaagca agatatgacg aagatcgtta tatcttgctt ctttatatag
    13441 gtagtttttc ataaatacaa atttgttatt ctctcatgat tatcagggta tatttttatt
    13501 tattatgtcg gtgttccagg aagtgtttta atttaataac gaagaaatta attgtttgta
    13561 gaatgaagga aactatttat tgggtagatg aatcaccacg aatagtcaaa aggagatttc
    13621 aggatatgcc aaaaatgaaa aaaatcattt tagcagtaat gttattttct acggttatat
    13681 cttttacagc cccttttttg cttacttaag ctgattttaa gttttggccc ttagtctgga
    13741 tctacgaggt gagagtcaag aatgaaaaaa ataattggag cttttgtatt tgcaatcatt
    13801 atcattatta tctgttttca aatagatgtt tttggtcaaa aaaagatagt tggacaaacg
    13861 gtcagcagta cgaacagtac ggttacaaag acaaaggaat catttgatga tacagaacaa
    13921 gagacattaa tcaaaatcgg aaaaaatgac cgtacactat atacagatga ctcgctaact
    13981 accccacttg caactataaa cggcggagag ctggcggagt ttctttctga aacaaaaaat
    14041 gcttatcaga tcaagacaaa tgatggctat actggatatt tagccctcga agatggaacc
    14101 aaagtcacaa agaatataca aacaaaaccg gaagagctat ctgatgcagt gattgtatta
    14161 gatcctgggc atggcggaaa tgatactggg gcattaagca atgatgaaca aacagaagaa
    14221 aaagatataa cattaagtac agccataaaa gtaaaaaagg cgctagagga tgctggagca
    14281 acggtttatt tgacccatac tacagatgaa ttagtacagc ttggagatat atgcgactac
    14341 agtgaagaaa aaaaggcaga tgtctttatc agtttacacg cagactctac ggaatatgcg
    14401 aatgaagcaa ctggaatcac gacatattat tactatggac aagaggaaac attagcacag
    14461 acaattgctg actccttcac tgatctgcct ctggattcaa gaggaatctc cactgggaac
    14521 tatcaagttc ttcgagaaaa tcttcaacct tctattttaa tcgagatggg ttatatgaat
    14581 aatgatagtg atttaaagga attagtaaca gacagttatc agcagcagat tgctgcaagt
    14641 ttgacacaag cattgaccac ttattttcag taataaataa gcccagccaa acaaaaatag
    14701 ctcctcatat ttttcgtttg gccgggctta ttatcgcaga tgcaagcttt taaacaccgt
    14761 ttaaggaaga ggtcgtgagc ctgccgttca actctgagtc acaaggagca atttcaaaaa
    14821 acagcttctc atgtttgatg actattgtga cttgtgaccg aggagttggc atgagaacac
    14881 cgtttaagaa aaaggttgtg aaatcaacgt tttgttctga gtattagaga aacaaacgga
    14941 aaaatagttc ctcatatttt gccgtttgtt gagctaatac cgaggatcag atgattgaac
    15001 accgtttatt cggaacaagg gactgtgaca tgacttttgt cacagttcca ttattttttt
    15061 agtagcttca aagctttttc tgtattggca aaatgaagtt tggcatattt ttcaagcata
    15121 ggcatgccgc ctttctccaa tagttttgcc gctacttggt cagatttcgt tccagctcct
    15181 gacggaaggg tgattccagc ttcagctgat gctttgtcta actcttccaa aaagctggca
    15241 cgactgatga tagaagcagc agcaacagct aaatgatatt gttctccttt agtaacgaag
    15301 tacagttttt cttgtaattg atttttttct aaacgcgcat attttttaaa atttgcttcc
    15361 ggcgtaaact gatcgatcaa aatcgcttct ggtttttctg gctcgatttt ttttagcagc
    15421 aaatggatcg cttgattgtg caaagcgact ttcatccgaa cggcattgta ttttggttgg
    15481 atctcattgt atttttctgg agataagaca agcagtttat aggggatggt tttttttaag
    15541 atgtcagcaa gctggatgat ttggctatct tttaactctt ttgaatctct aacaccaagt
    15601 ttacgtaatt ctgcaagctg atcacgtttc acataagcag cacatactgt tagcggaccg
    15661 aaatagctgc catttccgac ctcatcacta cctaaaacgg ataattgact gatatttttt
    15721 ggcaaagaag aggctgtttt tgctggcttg gcttgtttat cctgtgcctc cccccattta
    15781 tcagcttcta ttgctgcatt cgtaccttga aacatcactt ttccggatgt ataagcggta
    15841 atggtcgtcc cgtctttttt tgcagcaaag ctagtataag gaatctgttt atttaacaaa
    15901 taagagcgat agtatgcttt catttgacta agttggtcgt ttgttgcttt gataatgacg
    15961 ttgctcataa aattctcctc gtttttatac ataaaactat accgcaactc acgacttttc
    16021 gttttctaag agattgcgag acatagcatt tttttaaagt ttatcatata atagttaagt
    16081 atgtgaaaaa tatttgtgga gaacggtgaa agaaccaact tcatggtaca ctaaataaaa
    16141 ctttcatcaa ataggaggaa atgattcgta tggcgcacga aaaaacacgc tacaaagcgg
    16201 tgattgccaa ccaaacatat actattatcg gacgggaaac caagcatcat atggatatcg
    16261 taacgaagct gatcaatgaa cagttagcag aattgaaaca attatcacca caaatggata
    16321 atgaacaagc agcaatcttg atggctgtca atgcgctttc ggatcaattg aagaaacaag
    16381 aaagaatatt ggagctggaa gaagaaacag cagaattaaa gaaaaaaatg atcaaattta
    16441 cagagcttga aaatcgtgtg aaacgcattg aagcaatcga gaacgaagct cgggaagtat
    16501 tgaaagaaaa tggtcaagca gatcatacca ttaaaaatca tgtggaagca caacagattt
    16561 taaacgagaa acgaaaagga caaattaaac aaaaatcttc taattaagat ccttttatca
    16621 aaataagaaa aatttaaaaa agttagaaga gaaaggaacg tagcatgctg agtttgctga
    16681 ttttattttt attgctaatt gcgttttttt ctggagcacg tcgcgggttt gctttgcaaa
    16741 tcatattcgc gattggatat gtattgtcat ttattgctgc ccagcatttt tacaaaccat
    16801 tagcaagtca tttggaatta tacattccat acccagctgt caccccaaca tcaaagttag
    16861 cattttttga tcaggtattt gcctttcacc tagatgaagc tttttatgca ggaactgctt
    16921 ttctgattat tttgctaatt ggctggctgc ttacccgatt tgtgggggtt tttgtccatg
    16981 gattgacgta tgtgccgatc ttgagacagg tagactggat tgcaggaggc atcctgtcac
    17041 taatcatggc ttacgttact atatttttga ttttgcagtt acttgccttt gttccattag
    17101 atgtggtcca aaatcaattc ggcgagcata gtttcgctcg ttttatcgtt gagagaacgc
    17161 catttcttac caacaagatg tatgagcttt gggtaacgaa tattttgaat taaggaaaat
    17221 agtgctggaa aatatttcgt tttttgtaca gagtagttta tttaagaagg ctgcgtagcg
    17281 tatgtccggc acagctcttt tttcatagtg aaagataagg tgataaaatg aataaccgaa
    17341 tccttgaaac attggaattt gaaaaagtca aacagatggt cagacaattt gtagtgactg
    17401 cacaaggaaa agaagaactg gcagaattgg taccagtgag tgagaaacaa acgatcacaa
    17461 actggcttca agaaactgag gatggattga aagtgcaacg tctgcgaggc gggatcccta
    17521 tacctaaaat tgaaaatatc cgtccccata tgaaacggat tgagatcgga gcagacttga
    17581 atggagtgga gcttgcacaa gtttccagag tattgtctac gacaagcgaa ttgaatcgtt
    17641 tcattgatga tctttctgac agtgaaatcg aatttgcacg tttgtatatg tgggcagatc
    17701 agttagtcac gatccctgtt ttgagccgcc gtttaaagga agcaatcgat gaagacggac
    17761 gcgtgactga tgacgcttct cctgagttaa agagcataag acagaacatt cggcgaagtg
    17821 aacaagctgt tcgtgaacag ttagatggga tcgtccgtgg gaaaaatgca aagtatttaa
    17881 gtgatgcgat catcaccatg cgaaatgacc gctacgttat cccagtcaaa caagaatacc
    17941 gcggtgtatt tggcggtgta gtccacgatc aaagtgcttc aggtcagact ttatttattg
    18001 aaccaaaaca agtggtggat ttgaataatc gtttgcgtca ataccaaatc gctgaacgaa
    18061 atgagattca acgtatttta agtgaacttt ctgctgaact tgttccccat cgtcaagaaa
    18121 tcatccacaa tacttatgtg attggtaaaa tggatctgat gaatgcaaaa gcacgatttg
    18181 gtaaagaagt aaaagccatc gtgccgggaa tcagtgaaga caatcatgtc gtcttgaaac
    18241 aagcaagaca tccactgatc gatcaggaaa aagtagtttc taatgacatc acaatcggaa
    18301 aagactatca agccatcgtc attacaggac ctaacacagg tgggaaaacg atcacgttga
    18361 agactttagg tctgttacaa ctgatggggc aagcaggatt accgattcct gcaggtgaag
    18421 aaagtcaaat cggtattttt gaggaagtat ttgcggatat aggagacgaa cagtcgattg
    18481 agcaaagtct atcgaccttt tcttctcata tgacgaacac tgtagatatt ttatcaaaag
    18541 tcaatgaaaa aagtctggta ttatttgacg agctcggtgc aggaacagat ccgcaagaag
    18601 gtgctgctct agcaatcgca atcttagatg atcttggtaa aaagtctgct tatgtgatgg
    18661 caacaacgca ttatcctgaa ttgaaagttt atggatataa tcgggcaaat acgattaatg
    18721 ccagcatgga gtttgatgtg gatacattaa gtccaacgta tcgtttgctg attggcgttc
    18781 ctggacgaag caatgcgttt gaaatctcta gccgattagg tcttgataca gaagttattg
    18841 atgaagcgaa gcagttgatg aatgatgaga gccaagattt aaacgaaatg atcacagatt
    18901 tagagaatcg ccggaaaatg gcagagaccg aatatctgga aatgcgtcat tttgtttctg
    18961 aggcacaaga acttcacgat gatttgaaag aagcttacag ctatttcttt gaagaacgtg
    19021 aaaaagaaat ggaaaaagca aagaaaaaag caaatgaagt cgtgtcagag gcggaagaaa
    19081 aagcagaaaa aatcattgct gatattcgta aaatgcaaca gcagattggg caaggaaatg
    19141 tgaaagagca tcagttgatc gatgcaaaga cccaattagc aaatctacat caagaagaaa
    19201 ctttgaagaa aaataaagta ttgaagaagg cgaaagaaca aaaaacgttg aaaccgggag
    19261 acgaagtgtt ggttacgact tacggccaaa gagggacgct tttacgtaaa aacgggaatc
    19321 agtggcaagt agaaatcggt atattaaaaa tgaatgtgtc cgaagacgag ctgacgcctg
    19381 ttgctcctca aaaagagccg acacaacgag ttatccatgc tgtacgatct gaatctagta
    19441 gtcacgtgcc gaatcaattg gaccttcgag gaaaacgata cgaagaagcg ctaagtgagg
    19501 tagatcaata tttggattct gccattctag ctggttatcc tcaagtgact attgtccacg
    19561 gaaaaggaac aggcgcactt cgcaagggaa ttactgatta tcttaaaaac catcggagcg
    19621 tcaaaagctt tgagtttgca ccggcaaacc aaggcggaaa tggtgcgaca attgttaaat
    19681 ttaagtaaag cttactaaag gtaagcagat ggttcgctat ccaagtatag aaatgctata
    19741 ctagtcatag attttaaaaa tggaggtctt tgatatgtca caagtaatta cagataagac
    19801 atttaatgaa gaaacagata aaggacttgt attgattgat ttttgggcaa cttggtgtgg
    19861 tccatgtcgt atgcaagcac cgattttgga tcagttggaa caagaatatg atgaagaaga
    19921 attcagaatt gctaaaatgg atgtggatga aaatccagaa actcctcaac aattcggtat
    19981 catgagcatt ccaacattaa tgttgaaaaa agatggtcaa gtagtagaaa aagctgttgg
    20041 tgttcattca aaagaacaac tacgtcaaat gatcgatcaa tatttataaa aacttacagc
    20101 aaaaataagc tgagggtggg actgaatcca gttccgtcct cggttttttt gcggttgagt
    20161 taaggttatt caaattaata ttttttgagt ataattacgt tgtcaggctg gattgttttt
    20221 ttgacagaca tgctataata actttaattg aatatgaagg ggagtaccag atgaacgaac
    20281 gaatcaaaaa caaattagct ttacttcctg atcagcccgg ctgttacttg atgaaagata
    20341 aaaatggaac gatcatttat gtcggcaaag ccaaaatatt aaaaaatcgt gtccgctcat
    20401 attttactgg tagccataat acgaaaacgg aacggcttgt tagtgaaatc gaagactttg
    20461 aatacatcgt tacagaatcg aatatcgaag cattgctctt agagatcaat ctgataaaga
    20521 aaaatgatcc taaatacaac attatgttaa aggatgataa aacctatcct ttccttaaga
    20581 taacgaatga aaaatatccc cgtttggtga ttactcgtaa ggtactaaaa gacaaagcac
    20641 tgtattttgg accatatccc gatgtcggtg cggcgaatga gacaaagaag atcctcgatc
    20701 gattatttcc tctgagaaaa tgcaaaccta gtcagacgaa ggagccttgt ctttactatc
    20761 atttgggaca atgcctgtgt ccttattatt tcgacgtaga tccgaaagtc tatacgaaaa
    20821 tcgttgatga agtgaaaaac tttttaaacg gaggacacga aaaaatcgag tcagagatcc
    20881 atcagaaaat ggaaaaagct gctgaaaaca tggagtttga aaaagctgca gaataccgag
    20941 accagatccg tgccattgag acaatcatga ctcgccaaaa aatgacaaat actgatttac
    21001 tggatcgaga tgtatttggt tatgcgattg ataaaggatg gatgtgtgtc caagtgtttt
    21061 tcgtaagaca aggaaagcta attgaacgag atgtttcaat gtttcctttc tataacgaag
    21121 cagaagaaga tttcttgact tacctcggtc agttttatca ggaaaatgag catttcattc
    21181 ctaaagaagt cttgattcct gatacgatcg acaagcccag tgtagaagct ttgttagcta
    21241 cgaaagtgct gcaaccaaaa cgaggagaaa agaaaaaatt agttgaattg gcgagtaaga
    21301 atgcctcagt tgctttgaat gaacggtttg atctgattgc cagaaaacag gaacggacga
    21361 tcggagcagt tgaacgttta ggaaacgcga tgaatatccc gaccccaata cgtatcgagt
    21421 cttttgataa ctctaatatc atggggacga atcctgtggc tgcgatggtc gtattcattg
    21481 atggaaaacc ggcaagaaaa gaatatcgga aatataaaat aaaaacagtc aacggaccgg
    21541 atgattatgc atcaatgaga gaagtcatct atcgcagata ttcgcgagtg attcgcgaag
    21601 ggttgccttt acctgatttg atcttgatcg atggaggaaa aggacaagta gatgtggcaa
    21661 aagatgtctt agaaaatcaa ttaggaatcg atattcctat tgctggcatg gtaaaaaacg
    21721 ataaacataa aacaaatgag ttgctattcg gtacagattt ggctgtagta ccgcttgagc
    21781 gaaattcacc agagtttttc ttactccagc gaatccaaga tgaagtccat cgattcgcaa
    21841 tcactttcca tcggcagcta cgcagtaaaa acagttttgc ttcccgatta gatgaaattg
    21901 aagggttagg accaaaacga aaaaaaatgc tgcttaaaga gttcaaatcg ttgaaaaata
    21961 tcacagcagc cacgacagaa gaattacaag aaatcggact gccgaaaaat gtcgcacaaa
    22021 acgtatttga taaattacat caggaatgag gaaagggcac tttacaaaga aagtaaagtg
    22081 tcctatcatt ttatgtacaa caaaaagagc gtttacgttt tgttggtaaa taataaatcg
    22141 cttacgtctg gtgtctaagg atatatgtga tttcttgaag aaggagtgaa gaaatgttag
    22201 aagtcaagga tcttgttaaa acttttggga actacacagc tgtcgatcat gtctctttcc
    22261 aaatccccga tggaaaaatc atggggctaa ttggccaaaa cggggctggg aagacaacga
    22321 cttttcgttt gatcttggat tttttgacac aagaccaagg agaagtgtta tggaatggcc
    22381 atcatcttgg ggagaaagat tatgatgtca tcggttatct tccggaggaa cggggacttt
    22441 atccgaaagt aacgattcaa gaccaactgc tttattttgc agaacttaga gggaaatcaa
    22501 gaaaagagat tgaaccaaaa atcgactttt ggatggaaaa atttcaggta aaagggaaaa
    22561 agacggataa agtaaaatct ttgtctaaag gaaatcagca aaaagtccag ctgatcgcca
    22621 cgttaatcca tgaacctaaa ttgatcattt tggatgagcc attcagcggg ttagatccgg
    22681 taaatgctga attgctaaaa gatggaatat tggaattgaa aaaacatggt tcatgtgtca
    22741 ttttttctag ccacaatatg gataatgtag aaaaaatctg cgatcatttg atcatgttgc
    22801 gaaacggaaa aatggttttg aatggaaaag tacatgagat tcgtgaatca tttggccgta
    22861 cgaagttatt cttggaatct ggtttaagcc aacaggaagt agaagaaatc gaaggcgtga
    22921 aaaaagtgat ccttcatgaa gacaatacgt tagagattac cttagaagat cctgaagctg
    22981 ggaaagaaat ctttactcgt gcgactcagt tcggctacat tcctatgttt aaccagcaac
    23041 cgccaacttt ggaagagatt ttcaaattga aagcaggtga aatcgatgcg taagttttgg
    23101 attattacca aagatgtcta tttaaaaaat gttaagtcga tttctttctt gatcatgata
    23161 ttagtccctt ttatcatgct gggtatcatt tatgtagcag gaaactttgc tcaacaaaat
    23221 agtgatgtca ataaaatcgg cgtattggct gataatgagc aaatcagtca gcaaatgagc
    23281 caagtcaaaa cagatgattt tgagttcaaa gcagttgatt ctgaagaaaa agcacaaaaa
    23341 gagctttcgg aagaaaaaat cgatgcgtat ttagtagtct caactgagaa tgataagata
    23401 aatgggatgc tttatagcga aaattcatta ggacaaagta cacaactact gatacaacaa
    23461 caactgactg gcttgcaatc gatgcttcga gcgagtcaat taggcatttc accagaagaa
    23521 gtagctagct tgagccaaca agcaagtttg actcgacaaa aagtcaattt tgattcaaaa
    23581 ggaaaaatga cagtcggaga agataactcg acagtccaat acgtcgtaag ttatgtagca
    23641 acgattgtct tgttcattat tattttgacg tatgcgcaga tcattgcaca agagatcgct
    23701 tctgaaaaag gcacgcggat catggaagtg atcctgtcca gtacgactgc acaaaagcat
    23761 ttttacggaa aattaacagg tgttttactt gttgcattaa cgcaaatggc attatacggt
    23821 attatttttg gtataggata cagtcaattc aaagatatgg aaatggtcaa aaatatatta
    23881 gacggtatct cattggataa cttgattgga ccattcttgt ggtattctct tctattcatg
    23941 atctttggca ttttgatttt ttctgtttta gcagctttat gtggctcttt ggtcaacaaa
    24001 gcagaagata cagcaaaagc aattttgcca gtgacttatc tatctctagg cggatacatg
    24061 cttggattga tactaggagc ttcagatcca aacaatatcg ttattcggat cacttcgtat
    24121 attccattct tatcttcata tattatgccg attcgcttag caaatgagac agtcggtatg
    24181 ggtggagcat tgatttcctt gttggtactt gtagccgtaa cattcttatt gatgatcttg
    24241 tctgcaaaca tgtacaaatc gaatgtactc gtttatagcg aaggcggatt atggagttca
    24301 ttgaaacaat cgatttcaat tatgaggaat gaacgaaaaa aagcataaaa caatcctaaa
    24361 atacagaagg aagctggaca tctattgttc ccagcttctt tttgtataga cctattttat
    24421 ttattttact atattggata tatattcatt gaaaatagtg tataacaact ttataatatt
    24481 gagtatacca atttttggag gcgttttaat ggaccgttat ttagatttac tttcagaaaa
    24541 attcccctca acggaggatg tcatcacgga aatcatcaat ctcgaagcaa ttttgcagct
    24601 tccaaaagga acagagttat ttttgagtga tatacatggc gaatttcctg cttttgatca
    24661 tattctgcgt atcggttcag gaaatcttaa agaaaagatc aaagaccttt tttctgaaca
    24721 aatgacggaa acggatatca gccaattcac tatttttacg gcttatccag aatatgcatt
    24781 aacgactgat tggtacaaag aacaagataa atcgcagctg atccatcatt tgatcgatct
    24841 tttacggttt acgacagtca aatatacccg gtcaaaagtt cgaaaaggat tgccgaaaga
    24901 atatagctat atcattgagg aactcttgta tatcgatgac cgtatcaatg gaaaaaaaga
    24961 ctatgtaaaa aaaatcattg aacaacttgt tttgatgaag gaagaagaaa aatttttaac
    25021 gaaacttgca cagacgatcc aaaaatctgt catcgatcat ttgcatatcg ttggagatat
    25081 ttttgaccga ggaactcaag cagccaaagt gatggatcga atcatggatt tttcttctgt
    25141 agatatccaa tggggaaatc atgatatttt gtggattggt gcgtattgcg gctctgaggc
    25201 atgtttactg acacttttac ggattgcagc acgctataat tatttatttg aattagagaa
    25261 agaatatggg ttgaatttac gtccattgtt ttcttttgct catcaaactt atcagaagaa
    25321 tccagtattt gcgcctaaaa acagtaaaaa tctatccgaa agagagcaag aagaattaga
    25381 aaaaatccat caggcacttt ctatccttca attcaaatca gaacatcagt tattggatcg
    25441 tcgacctgaa tttaaaatgg acgatcgtaa attgctggaa aaaatcgact atgaagcatc
    25501 aacgattgat ttagaaggtc agctctatga gttgaaagga acttgttttc aaacgatcca
    25561 gccagatgat ccaaaaaaat tcttggaaga ggaacaaaaa gtgattgata gtttgatgta
    25621 ttcattccag cactctttga gaatgcaaaa acatatgacg tttttgatcg aaaaaggggg
    25681 aatgtatctc acgaacaatc agcatgtgct gtttcatggc tgtatacctg tagacgagaa
    25741 gggacagctc ttagcatttg aattagacca atcttatcgc ggaaaagaac tgctgggctt
    25801 ttttgaaaaa cagataactg aaagcgcaaa agatctgact gcaaaagaag atttagcaac
    25861 cgatttgatt tggtatgcgt ggagtgggcc attttcgcct ttattcggca agagtaaaat
    25921 ggcgactttt gaacgttatt ttctcacaga gcctcatacg cacgtcgaga aaagcaatcc
    25981 ttattatcac ttgcgagatg aagagtggtt cagtgaaaaa attttagcag aattcgacac
    26041 aaaagaagaa gggtcagcaa tcattaatgg gcacacgcca gtaaaagtaa aaaaagggga
    26101 gtcaccgatc aaagcaaatg gaaaagtatt tgtcattgac ggaggtttat ccaaagctta
    26161 tcaaaaaacg acaggaattg ccggttattc actattatgc aattcttatg gtttccaaat
    26221 cgtgacacat tatccgtttt tgcctattga acaacaattt gcaaaaaaat ccgaccaaac
    26281 aaatgtgaaa aaagtaatcg aacagcaact accacgcaaa ctcaatcgtg atacaacaaa
    26341 aggtatggaa ctgcagcagc agattaccca gctcaaaagg ctgttggact atcgaaagga
    26401 cgattgagaa gaattccagt gaacattgtt ccatagactg gagactgaga caaaagtcgt
    26461 gtcgcagtct ctttttccgg ataaacggtg ttcttctgcc aactcctcgg tcacaagtca
    26521 cactattcaa caaacatgaa aagctgtttt ttgaaattgc tccttgtgac tcagagttga
    26581 acggcaggct cacgacctct tggtataaac ggtgttcaaa agccagtttc tcggtattaa
    26641 gccaaattta tgcaaaaatg tgaaaagcca ttttcacaaa atttttctta atactcgaaa
    26701 ctaaacagct ttttcacaac cccctcagaa agtctattaa aattcattca caaagaaatc
    26761 gaataagcgc tgttcagatg gatgtacacg gtgggtaagt tccggatgcc attgaacacc
    26821 gaggatttta tgcatatcat ctttgctttg aaccgcttca acgagtccat cgttagaaaa
    26881 agcgatggct tttaataaag gtgaaagatc tttgactgcc tgatgatggt aagaattcac
    26941 aaaatatgga tcggggagaa ggttgcttaa caaactgtct gaaacaatct tgacttcgtg
    27001 agtcgtaaat tgcggggcag tgggctgttg ttcatgtttt actgaccact ttggatataa
    27061 tgaaagatct tgataaagtg taccttccaa aacgacattc aatagttgga gtccccggca
    27121 gactgcaaaa attggttttc tttgtttcaa tgcttccaag atcagtgcct gttcaaattg
    27181 gtctcgttga atatttgttt ccgttagctt tggatgagga tcttccatgt aaagttgtgg
    27241 actgacatct tgaccacctg caagaataag tttgtcgatt tgtccaatca gttgaggagc
    27301 tgaatctgga gacatgactg gcagaataag aggcaatcct tgagcatcta aaactgcatc
    27361 cacgaatcct tgcggtgtat agctcacttg atttccttgg aaagtatctg ttgctcgaat
    27421 cagttgattt ccggcaatgc cgatgattgg tttcatttgt attcccccta aagtagactt
    27481 attgtaacaa ggatttaaaa aaaattaaac tatgtaagac ttgcccctat acttatctgt
    27541 tcttgctgtg ttactatctg taaagagaaa tttcgtgtga aattcatgac gatagttgaa
    27601 aatattgctt aatttgttat aataaaaagt aagcagaaat aaaaaggttg ggcgtaagct
    27661 tcaaggatct agttcttcaa ggggtgagaa ggacatttta ttgaaggggc ctgcctatac
    27721 taagttatct ttagaggtac atactttcaa tgaaaaaaga aagcatgtac ctctttttta
    27781 aatcgaaagg aagtgaagca agtgttagaa gctttggaac aaatccgaaa agcagaagaa
    27841 gaaaatgaaa agcgtgctca aacactgcgg cagcagctga agatctatgc aacagaaaaa
    27901 gagcaggaat tggaaacgat ccaaacaaac tatcgacaac aactaaaaca gttggtggaa
    27961 gaaaaagaac aatttgaaat acaagaatta gaaaaagaaa aaatgaaatt gaaagcagaa
    28021 gcagacaagg tgcaagcaac tttgaaagat caatatcaaa agcatcagag tcaagcgatc
    28081 ggtgcgatca ttgaaagggt gaaagaaact tatggccgtc actaagatgg aaaaagtgac
    28141 cctcatttca gataaaagaa atcaggagag gattttacaa gcagtacaag gaatccaaaa
    28201 cgttgaaatc cgggatctgt atcaaaatag aacaaacaac cagtgggtgg agaagtattt
    28261 tccagatacc acgattattg ataaagaagc aaaattaagc gctttaggta atcggttgaa
    28321 agacatccaa gaagctatcc aattcataca acaccacggc gatagccgtc aaaagaaact
    28381 ccatttgaaa cgtcaagaac tttccttaca agatttggaa gccaattatt ccgaagaaaa
    28441 tttcataaat aaattgaaag aagtccttga tttaaaagaa aagtgggaac aactaactga
    28501 agaacgtgat cgtttagaag aagaggaaga atggcttctt cattggcaac agctggatat
    28561 tgctccaagt atgtatgcaa gtaagacgac catttttgag atggggactg tgagtgcagc
    28621 aaattttgaa agtttcaagg aagaactgag taagcttgat gacgtttata tggaagaaat
    28681 agattatacg ccaaaacaag tttatctttc gtatgttgct ttaaaaaaat cagttgctgt
    28741 tatagaagaa attgctggga aatacgggtt caataaagaa acgtatcctt atgaacaaaa
    28801 tcctaaagaa aaactgcaag agaccaagca gcaattatcc attgttcacg agcagcaaaa
    28861 gaagataacg acagcgttag gtcagtgcag tggctatatc caagaatttg aatgggtaga
    28921 agaagtcaca cttgccgttg cagaacgaga aaaaataaaa gaacggttta tccatgcgac
    28981 ttatctgatc gttttgcaag gttgggtaga tgcagaagaa aaacagaatt tgctgcatgt
    29041 gttaaacgaa accgtatcag aagaagatat atacgtcagt ttcgaaacac caaactcaga
    29101 agagattcag caggaagtcc ctactaaatt gaaaaaccat ccgcttgtcg aaccttttga
    29161 attgctgact gaaatgtaca gtctgccaaa atatgaagaa gtagatccaa caccttggat
    29221 gacaccattt tatcttgtct tcttcgggat gatggtcgca gatgttggtt atggtttgct
    29281 gatgctcatt gggacaatac tagctcaaaa actacttgtt ctaccacgcg ggatgaaacg
    29341 tttcgtaaaa ttctttgaga ttctctcgat accatcgatc atctggggat tgatctacag
    29401 ttcatttttc ggacagtcat taccaaaaga actgtttggc atccgcttgc ctttcccaat
    29461 cctatctacg acggatgacg tcaatacgat tttgatttta tccgtgattt tcggtctgat
    29521 acagattttg gttggattat ttgtggcagc aaaggaaaat atcaggagaa aagattactt
    29581 gagtgctgtc agtgatggat ttgcctggca agggatccta attgggatcg ttattgcgtt
    29641 ggttggtgcc atgttgataa aaaatacagc atttgtttac cttggcgctg ggctatcgat
    29701 cattgctgcc ttatgtatct tgatcgttcc gattatccaa acgccgtcta aagtcaaagg
    29761 tgctgccaaa ggtgcgtata atctttacgg actgaccggc tatatcggtg atttagtcag
    29821 ttatacacgt ttgatggcat tgggtatttc aggcggaagt attggagcgg cattcaatat
    29881 gctagttgct ttcatgccgc cagctgctcg attcagtgta gggatccttt tgatcatcgc
    29941 tttacacgca ctgaatatgt ttttgacact gctaagtgcc tatgtccatg gcgcacgatt
    30001 gcagtatgtc gaattttttg ggaagtttta tacaggaggc ggacgtgcct ttgatccgct
    30061 gaaaacggcg gaaaaatacg tcaacatcaa tcacaagaaa aaaaacaata aataattgga
    30121 ggatttttat ataatgatgg attacttaat tagtcaaaat ggtggaatgg tatttgcggt
    30181 attagcgatg gcaacagcga cgattttttc agggatcggt tcagctaaag gtgttggaat
    30241 gacaggtgag gcagcagcag cattgacaac aagtcaaccc gaaaaattcg ggcaggctct
    30301 gattctgcaa ttgcttccag gcacgcaagg tttgtatgga ttcgttattg cctttttgat
    30361 ttttatcaac ttaggaaatg acatgtcagt tgtacaagga ctgaactttc taggtgcttc
    30421 tctgccgatt gcttttacag gcttgttttc aggtattgcc caaggaaaag tcgcagcggc
    30481 aggtattcaa attttagcga aaaaacctga acatgctaca aaaggaatca tttttgctgc
    30541 gatggttgaa acatacgcga ttttaggttt cgttatttcc ttcctattag tgttgaatgc
    30601 ctaagcataa aggaggaaaa gcagatgaac gccattgaaa aaatcatctc tcagatgaac
    30661 gaagcagcag agcaggaaag agcggcgtta gaacaagaag agcgaatgaa gatcgatcaa
    30721 aactttgaac aaaaacgtac gcaagttgaa acagaacatc aaaaacaaaa agaaaaacaa
    30781 atcgaattac tcgaaaaaaa ataccgtcag ctaaggaatc gccagcaagt agaagtacga
    30841 caagaaaatt tgaatgcgaa gcaggaattt ttaagacgat tgtttgcaga tgcggtaact
    30901 gaaatggaaa attgggatga atctgaacaa atccagttta tcaaaaatgc attgtattca
    30961 ttacctttga caggaaaagt agcattcatt gctggagaaa aatcagcagc ctatctttct
    31021 cagacgttgt tggatgaatg gaacaatgaa cttcccttta tgatggtttt aagtgatgaa
    31081 actgttgctg atcaagcggg ttttctgata aacgatcaag gagttcagta taattttctt
    31141 ttcagcagcc ttgtacaaga tatccaagga acgatgagtt ttgagattgc caatcaatta
    31201 ttcgaataag gagggatcag tgtatggaat accacgaact aaatcccttg attcgcggaa
    31261 gagagcttga acttttgtcc aatgagacat ttgaacggat gattcaaaca aattctgtcg
    31321 aagcacttgg tgaaatattg aaatccacga tttacagtcc atatatttat gacggatatg
    31381 aatatgactt cgaacagaat cttttaaagg agcagagccg tctatttcgc tggttaaagg
    31441 aatcagcacc ggagcctgaa atcgtttgga tctatacgat gcgttatact ttccataatc
    31501 tgaaggtttt gacaaaagct gagatgacaa atcaaaatct ggaccatttg tatatcgacg
    31561 atggatttta ttcattagaa accttgaagg atgccattca tacgcaagtt tcaaatgaac
    31621 ttcctgaaag cattatggac agtatacgag aagtacgtga ttattttgaa gagtctacca
    31681 ttcttcaggg aattgacgtg atttatgatc gacagttttt gacagagcag cgacggcttg
    31741 ccgataagct aggatatcaa gaattgctga cagaagtcat tgcttttatt gacttgacca
    31801 atatcacaac gatggctcga ggaatattgc agaaaagaac atatgggttc atgacgacgg
    31861 tactttccag ctcgggaagt atcgaaaaag aagtattttt gaactttgta gataaagata
    31921 tggaagatta cacgaatttt ctattagaga cagattatgc tgattttctg cgccctgtca
    31981 tccgtgaggg aaatattgat ctcgtaaagc ttgaacagtt gaaagatgat tatctaagtt
    32041 cattgtatca agaagcacaa acccaggctt tcggaccact gccactacta gcctttttga
    32101 acgcaaaaga ggtagaaagc aaaaaccttc gtttactggt tatcggcaaa agaagccatt
    32161 tcgaatcaga aacaatcaga aagcgggtga gacaagtcta tgacgcataa gatcggtgta
    32221 gttggcgaca aagattctgt tttgccattc aaattgtttg gctttgatgt tcgttatggt
    32281 acaaccaagc aaaccgttcg tcaggcaatt gaagaaatgg caaagaatga gtatggcgtg
    32341 atttatgtca cagagcaatg tgcagcattg agcccagaaa cgatcgaacg ttacaaggaa
    32401 caaatgatac ctgctatcgt attgattccc aatcatcaag gatcattagg gatagggctg
    32461 gaagaaattc aaaaaaacgt agaaaaagca gtaggtcaaa atatcttata gtatgaaaag
    32521 gagatagaaa ttttgcaaat tggaaaaatc ataaaagtct ccggacctct tgtaatggct
    32581 gagaacatgt ctgatgccag tatccaagac atgtgtctag tgggagatct aggagttatc
    32641 ggagaaatta tcgagatgcg tggcgatgtg gcgtctattc aagtatatga agagacttct
    32701 ggaattggtc caggcgaacc ggttcgctct actggtgaag ctttatctgt tgaattagga
    32761 ccagggatca tttcacaaat gtttgacgga atccaacggc cattagatac ctttatggaa
    32821 atcacacaaa gtaatttctt agggcgcgga gttcaattgc ccgcattgga ccatgagaaa
    32881 aaatggtggt tcgaaccaac agtagaagcc ggagaaacgg tgagtgctgg agatgttatc
    32941 gggatcgtag aagaaacaaa agttataaaa cataaaatca tggtgccaaa tgggataaaa
    33001 ggaacgatca aaacaatcga aaaaggttca ttcactattg atgaaacagt atgtgtcatt
    33061 gaaaccgaaa atggtgacaa aaatttgacg atgcttcaaa aatggccagt aagacgtagt
    33121 cggccaatca aagaaaaatt aaacccggat gcacccatga tcactggaca gcgagtgatt
    33181 gatacattct tcccagtgac aaaaggagga gcagcagctg tacctggtcc ttttggtgca
    33241 gggaaaacag tcgttcagca tcaaattgca aaatgggccg atgtggacat ggttgtctat
    33301 gtgggatgtg gcgagcgtgg aaatgagatg acggatgttt taaatgaatt ccctgaattg
    33361 attgacccta atacaggaga atcgttgatg gaacgtacgg tattgattgc taatacatca
    33421 aacatgccag tagcagctcg agaagcttct atctatacgg gaatcacaat tgcggaatat
    33481 ttccgtgaca tgggttatga cgttgctatc atggcagact ccacttcacg atgggcagaa
    33541 gcacttcgtg agatgagcgg acgtttggaa gaaatgcctg gtgatgaagg ttatccagct
    33601 tatcttggtt cacggcttgc ggaatactat gaacgatctg gaagagtcat tgcattagga
    33661 tcagaaggtc gcgaaggaag tataaccgca atcagtgctg tatccccgtc tggaggggat
    33721 atttcggaac cagtcacaca aaatacattg cgggtcgtaa aagtattctg gggtcttgat
    33781 tccagtttag cccaaaaaag acattttcct tcgatcgatt ggatacaaag ctattctctt
    33841 tattcaacag aagtagggaa gtatatggat catatccttc aagctgactg ggcatccatg
    33901 gtcaccgagg gcatgcgtat tttgcaggaa gaacagcagc tgaatgaaat cgtgcgtttg
    33961 gtagggattg attccctttc agataatgac cgtctgacat tagaagtggc aaaatccatt
    34021 cgtgaagatt atttgcagca aaatgctttt gatgatgtcg atacattcac ttcaagagag
    34081 aaacaattca aaatgttgaa gatgatcttg acctttggtg aagaaggacg ccgtgcgttg
    34141 tcgttaggtg cttatttaag tgagatcatg gacggtaccg tatcgattcg tgaaaggatc
    34201 ggacgaagca aatatatccc ggaaacagaa ttagaaaaac tagatcaaat tattggtgaa
    34261 atcaagcaaa cgatgcaaac gatcgtttca gaaggaggca tgagcaatga ttaaagaata
    34321 tcgtacgatc ggtgaagtcg tcggtccatt gatggcggtt gaaaaagttg ctggtgtcaa
    34381 atatgaagaa ttaatcgaag tccgtatgca aaatggcgag attcgtcgtg gacaagtatt
    34441 ggaagtccaa gaagataaag caatggtcca aatattcgaa ggaacaagtg gtatcaattt
    34501 acgtgactct tctgtacgat ttttaggcca tcctttagaa ctaggtgtat cggaagacat
    34561 gatcggtcga gtattcgatg gtttgggacg accgaaagat aacggaccag agatcctgcc
    34621 tgaaaagcat ttggatatta acggagaagt aatcaatcca gtagctcggg attatccaga
    34681 tgagtttatc caaacaggta tctctgcaat cgatcatttg aatacattag ttcgtgggca
    34741 aaaattacca gtattttctg gctctggtct tcctcataaa gaattagctg ctcagatcgc
    34801 gcgacaagca acggtactcg attcatcaga tgatttcgcc gtagtctttg ctgctattgg
    34861 aatcactttt gaagaagctg aatttttcat ggaagatttt cgtcaaacgg gcgcaatcga
    34921 ccgttctgtc atgtttatga atttagcaaa cgaccctgca atcgaacgta tcgctactcc
    34981 tcgtatggct ttgactgctg cagaatatct tgcttatgaa aagggaatgc atgttttggt
    35041 tatcatgaca gacatgacca actatgcaga ggcattgcga gagatttctg cagcacggcg
    35101 agaagttcca ggaagaagag gatatcctgg gtatctttac acgaacttag ctactttatt
    35161 cgaacgagca ggaagaatcc gcggactaaa aggatcggtt actcaaattc cgattctaac
    35221 aatgccagaa gacgataaaa ctcatccaat ccctgacttg actggttata ttacagaagg
    35281 acagatcatc ttgactagag agctttacaa gagtgggatt cagccaccaa ttgatgtact
    35341 cccgtctctt tcgcggttaa aagataaggg aactggaccc ggaaagacaa gagaagacca
    35401 tgcagctacg atgaatcagc tttttgcagc ctatgcacaa ggaaaacagg caaaagaatt
    35461 agccgtagtt ttaggtgaat ctgctttatc tgatgtagac aagatctatg cgaagtttgc
    35521 tgagcggttt gaaaaagaat atgtcaatca aggattctac acgaaccgtt cgattactga
    35581 aacacttgat ctagggtggg aactgctatc gatgttgcca agaaccgaat taaaacgaat
    35641 caaagacgac atgctggaca aatatctgcc agaagggaag tgagttctga tggcacgatt
    35701 gaatgtgaat ccgacccgca tggaattgac tcgattgaaa aaacagttga caactgccac
    35761 aagagggcat aaattattaa aagataagca agatgaactg atgcgtcaat tcatcctgtt
    35821 gattcgaaag aacaaccagc tgcgtcaaga aatggaagag tctatgacag aagcaatgtc
    35881 tgattttgta ttggcaaatg cttcgatcac ggaacctttc atcgaagaat tatttgtttt
    35941 gccggcggaa aacgttgatt tgtctatcgt agacaaaaat atcatgagtg taaaagtacc
    36001 tgtgatgaat tttgaatatg atgaacagct gacagacaca cctttggaat acgggtattt
    36061 gaattccagt gccgaactgg atcggtcaat cgatcggttt actaccctgc ttccaaaact
    36121 tttggaactg acagaaatcg aaaaaacttg tcaactgatg gcgagtgaaa tcgaaaagac
    36181 acgtcggcga gtcaatgcat tagaatatat gacgatccct caattagaag aaacgatcta
    36241 ttatattcgt atgaagctgg aagaaaacga gcgcgcagaa gtaacaaggt tgatcaaagt
    36301 aaaaaatatg ggtaccactg actaagtggt atcttttttt aaaagaggaa aacgatgatt
    36361 aaacaaagca aacaaataaa gaaacgtttg ccggctgttc agcttctcgc attaggattt
    36421 tttctcctga ttttagttgg cggcggccta cttaccctac cattttttag taatagtggg
    36481 catgggacaa attttatcga tgcgcttttc actgcaactt ctgctgtctg tgtaacggga
    36541 ttgacaacat tgaatacagc agagcattgg aacagtgctg gtcaattttt gatcatgctt
    36601 ttgattgaga tcggcggtct tggttttatg atggttccga ttctatgctt tgcattgata
    36661 aagaagaaag tcagtctcag cacacgtatt atattaaaag aagcgctgaa tctagaagaa
    36721 gtatcaggtg tgatgaagct catgctttac atcctaaaat tggcctttgt gatccaattg
    36781 attggtacgg ttgctttatc ttttgtattt gtgcctgaat ttggctggtt gaaaggtatc
    36841 tggtacagtt tgttccatgc aatctctagt ttttgtaatg cagggtttga tttgttagga
    36901 gacagtttag ccaatcacca gcaaaatgtt tatttgatca tggtggtatc tgctttgatc
    36961 atttctggtg ggttaggctt catcgtatgg cgtgatttac tggaatatca tcagaaaaag
    37021 aagatgacga ttcattcaaa aatcgcatta accgttacag gtaccctttt attaggcgga
    37081 ttcgttgtgt tctttttcac agagcgcaat ggggcaacgc tagtggaagg gaatatgttt
    37141 caacgattgg caaacacctt ttttatgagt gtgacaccta gaacggctgg atattattca
    37201 gttgattacc tccatatgag ccatgcaggt ctgattttaa cgatgttttt gatgtacatc
    37261 ggcggaacat ctgggtcgac ggccggcgga ttgaaaacaa ctacgttagg tgtgttgctg
    37321 atccagatgc gttcgatgtt gaaaggacgt acgagagcgg aagcatttgg ccgtaccatc
    37381 cgacaaggcg cagtgttgcg ggcacttact ttattttttg ttacgttgac gttgtgtgta
    37441 gtcgccatca tgattttatc ggtgactgaa acgataccta aaacttctgg catcgaatat
    37501 attgcttttg aggtcttctc tgcgtttggt acagtaggtc ttacgatggg attgacgcca
    37561 gacttgactg caatagggaa attgatcatt atagcgctta tgtacattgg acgagttggt
    37621 gtattgactg tggtcttctc tctgatgaca aaagcacaaa gaacacaatc aaaatacaaa
    37681 tatccagaag aaagtgtcat gattggataa tttcatcttc tgacagaaac ctagtgattt
    37741 agtaaaataa gaaaataaaa taatttttct tgcttcttgg atactttaag tgcaaaatgt
    37801 tcgtttattt tttgaggcac tacccgttgt tgaacctcgg gtagtgcctc ttttttattg
    37861 aaaggaatca ataagatttg attcctttat ttatcaatag gttataattc atattttttt
    37921 attttttctt ttacgatact tagtccagaa gctaaaattt caaggttatt agaggatagg
    37981 gaaattcgaa cgaatgcatc tggttgcgca cgtgtagtaa agcgtctgga atgataaagt
    38041 cggataccgt tagcaagaaa gtcattctca attatcttag ggtcaatctc aggatcaact
    38101 ggaagaattc gatagtaagg gacacgattc gttggttttt ctactttgaa aagagaatca
    38161 aaaagctgat tggctctttt tgtaagactt aatttagttt ctaagatcct atttgcttca
    38221 tttgaatgga ggatttgagt gatgacttcc acatctaatc cagaagtttt cacatttata
    38281 ttaaaaattg cttgttctat cttgctttgg acatgtactg gaactacaag ataagcaact
    38341 cgcaatccag aacaaataaa ttttgtcatt ccagctaagt agattgtttg gttaggtaat
    38401 aaattttgga aaggaggaat gatcgtatgt tgatagtaag ttgttaaaaa tgaatggata
    38461 tcatcttcaa taacccatag accttctttt tcaatcactt cggctaattg ctctcgtctt
    38521 ttgtgagaga tttgaaaccc tataggatta ttacaagaag gcataagaaa gacaccatga
    38581 atcttctttt ttctacattc ctgaatcaat atatcaggtc gcattccttg ctcgtcaaaa
    38641 tcaattggaa cgatctctaa atgatataac tgagccaatt caatgaaatt agcgtatgta
    38701 tatcggtctg ttgctattct atcacctgga gagaaaagtg cagaaagtgt gatagccaat
    38761 ccattttgaa caccggaaac aatagataga gattctaagg acggaatgac tccttgagtt
    38821 tttaaccaat ttgctgcagt agtcaattga aaatttgtgc ctttgggatc ttggtaatta
    38881 agcaaaccaa caagatttgg gttattacta gttgattgaa taaacgggac aacgaattta
    38941 ttacattctt caaaagaact aaccagacca aaatcaatga tatgttcggt tacttcattg
    39001 gtagagatgg tgatggactc aaagacattg ggagaaataa atgtgccact tccaatattc
    39061 gtatacagca aacctttctc aattccatat ttataagcct tgccaacggt agtaaaattt
    39121 aaatctaaat aatcagctag ctctctttgg gagggtaact gagtgttttt ctgtaattta
    39181 ttctttaaaa tatcttgttc taattgttga atcaacgatc gataataagg acgcttcaat
    39241 ttttgtttgt ctggtcgcca agttaacggg taattgtcat aagaattaat aggcattttc
    39301 tccactcctt aaaattgtat accatacaat tttaccattg attgtattga ttttagaagt
    39361 taatcttttg tgaggaggga attgtctatg aaaattatta attttgagga agtagtagct
    39421 tcttttagtt ttgaagaagc gattcaagta atgaaaaaat gtttttttga ttatgaaagt
    39481 ggtaaaatca gccaaaatcc tcgattggtg gaaattttac ctgacggaaa aggcaaaaat
    39541 atgtttgcga tgatgcctgc ttatttgggg gagaacagat attttggcac aaaagtcatt
    39601 accgcttttc cggataatca tcagtatcat ttaccttctc atttaggaga gattttcttg
    39661 tttgatgctc aaaacggact acccaaagca ttgataaacg caaatgcagt cacctggatt
    39721 cgaacagctg ctgtatctgc gctggcaaca gattacttag caaatccgca tgcagaaaca
    39781 cttgctttaa ttggagctgg tcaacaagca ttgtcgcatt tgactgcgat ttctaccatt
    39841 cgtcccatca ctacagtgtt tgtttacgat attttagaag aaagacgaaa tacttttatc
    39901 gctaaagcta aaaaacagta tcctaaaata acgtttataa atgcaatatc agtagaagat
    39961 gcagtacgtc cagcggaaat catttgtacg ttgacctcta gtaaagaggc atttcttcaa
    40021 aaagagtggg taagggaaga cgcacatatc aatgctgtgg gcacatttac tcctgataca
    40081 agagagataa gtacatcgtt gatggaaact tctcaaatct atgtagatga ttactcagct
    40141 gccttaacag aaagcgggga cctgcttata gccatggcag aaggagattt agaggaatct
    40201 tgtattgttg gtacattagg cgaattagtt tctgagaaaa aaacatttta taaaggagaa
    40261 tcgaggccga cgattttcga cgcagttggt ctagctattg aagatctttg ttgtgcagaa
    40321 tatatttata acaaattaga gaaaggggct ttaaaatgaa cttagattat tacgtagttg
    40381 atgcatttgc agatgaggtg ttcaaaggaa atccagcagc ggtttatgtg ctagaagaat
    40441 ggctgccaga aggtacgatg caaaaaattg ccattgaaaa caatttatct gaaacagcat
    40501 ttacagtgaa gaaaaaccaa gaatttgagc ttagatggtt tacgccagat cgagaaatcg
    40561 atctttgtgg tcacgcgaca ttagcaacag catttgtttt atttaactat tacaaaatac
    40621 ctgatgaaac gattaaattt tctactcaaa gcggtaatct atttgtgaca agaattaaag
    40681 attattatta catggatttt cctagtatta tgccgaaaaa agtgccgata ttgtctgaat
    40741 atgaagaagc gattggggct aagattaaag aagcctactt agcacgtgat ttatttttcg
    40801 tattagaaga tgaaaaaacg gtggctaaat tgcagccaga ttttacagct atcaaaaatt
    40861 ttgaattagg aataggagtc atcgtgacag cagaaagtgt gcaaaaagac tttgtttcta
    40921 gaaccttctt tccaaaatta acaatcaatg aagatccagt atgtggatca gcacattcta
    40981 atcttattcc ttattgggca gaaagaatga ataaaacaaa attgtcagct tatcaaatgt
    41041 catcaagggg cggggatcta gaatgtgaat taaaagaaga tcgtgtgata ataggaggaa
    41101 aagcagtttt gttttctaaa ggtacctcgt ttatttgatt tctttcaaat gaattaaaaa
    41161 taaattggtg gagagtggca accttatagc tacaatggtt gttaaaaaaa gacgcaaact
    41221 ttttcaattt aatgaaaagt ttgcgtctca ttttaattat tggtgtttgt tttttattca
    41281 atcaagagta aaatgcccca tactaactat cctcggatga cttcgatttt ataaccatca
    41341 gggtcaatga caaagtagta agaaggcgca gtgccaggta atccttttaa gtcagtaatc
    41401 tcaagaccag cagctttatg ttgctcgtgt aatttttcta gatcatcagc tgctatagcg
    41461 atatgaccat agccgtctcc tagatcatac gcaccatgat catagttgta agtcaactct
    41521 aattcatagt catccccagg aagtgtcaaa taaacaagtg taaatttgtt ttctggaaaa
    41581 tcacggcggc ggctttcttc aaaaccaaat gccttttgat aaaattcgat tgatgcttca
    41641 agatctttca ctcgaacaca tgtgtgagcc attttcatag attcatctct ccttttcctt
    41701 ttactcaatc ataacaaaaa gaagtaagga aatagttgat ttgtgcttgt tcatgagaaa
    41761 tttctcatgt aaaatggata gaaaataaaa ctgttaaggt ggaaactatt catggataaa
    41821 ccaatttttg gtgaaaaaaa gcaatttgct gattatcaaa cccgttatgc agcatatatt
    41881 gtcatagaaa gagatcagca gattgcagta atcgaggctc caaatggtgc tttttttctt
    41941 cctggcgggg aaattgaagg agaagagacg aaagaagaag cgattgtccg tgagctgata
    42001 gaagaaatgg gaattgtggc agaaatttct tcttatctgg gagaagctga tgagtatttt
    42061 tactcgaatt atcgtgcaac ttattattat aatccaggat atttctttgt tgctgattct
    42121 tggaagcgta taggagaacc aactgaaaag accaataaaa tttggtgggt gagccctcaa
    42181 gaagcgcttg tgaaattgaa acgtggtagc caccgatggg cagtcgagag atggatcgaa
    42241 aaaaataaaa actgaaagaa agcgagtaga tcagctttct ctcagttttt ttatttatta
    42301 cagtacatat tttttgattg cttcagctac accgtgctcg tcgtttgatg aagtgatgac
    42361 atttgctgct tctttgacaa gagaaacggc atttcccatt gctactccta gaccagcata
    42421 ttcaatcatg gataagtcgt tctcgttatc tccgatagcc atgatttcat cttgatcaat
    42481 accaaggtgc tgtgcgagat tcgcaactgc cgcaccttta cttgcttctt tatttagtac
    42541 ttcgaagtaa tagggcgcac ttttgaccgt tgtgtattta tcacggaaag tttgcggtaa
    42601 acgcgcaatt gctgcatcta aaatttctgg ttcgtcgatc atcatcattt tgacgatgtt
    42661 catgtctggt gtcatttctt caggtgttcg atattttagc ggcatcttga ctaaacttgc
    42721 ttcgtggatc gtataagcgc tgatatctcg attaggcgtg tagatcgctt tgtcatcgat
    42781 cgaatggaga tgactgccga cacggcgtgc cattacttcg atctctagga aatcttcatg
    42841 tgtcagtccg tgacgggcga tgattttacc tgatttcgtt tgttgtacga gtgccccgtt
    42901 ataagtaata acgtaatcat tatcttgaaa aaggttcaac tcgtttaact gttcctggac
    42961 acctggtaag ggacggccag tgcataaaac gatcgaaaca ccttttgcaa cagcagcggc
    43021 aatcgcttct tttacttctt ttgttacttc tcttttctca tttaataaag taccatcgat
    43081 gtcgatagcg actagtttga tagacataat ttcctccaat atattttaat ttatttcaat
    43141 caatgcgcca ttacggatat ggctggcaaa ttcttgataa gtttcgtcaa ataaatcata
    43201 atgatcacgc aaggacggat caaccatttc ttttggaaag aaaaatcgct catctccttg
    43261 ttcttgtccc gctaatgcag caacaagctg actaacctgt gataattcta tcaaagttcc
    43321 gtcatttcgc aaaatctcga tttgtgtgcg atgtctgcct tgttctgggc gataaaaatc
    43381 ataaggtaga tcgtagctag aattcacagc agtgtaataa acaggattat atccgacctt
    43441 ttctactaac aaagtgagtt cttggactaa ttttgaatcc cggttgccag aaaaagtagc
    43501 agatttcagt ggtttacgat tcaaaaaacg tttagctaaa tcatttaaaa taggatcagc
    43561 agattcagac cattgagtaa agtaagtgcc caagacccca tcatcaagtt tgaggtattc
    43621 ttctaaagta aagcttccgt caagaaatgg cagaagtaat tgagaatgga gttcaaaact
    43681 gctggcatct tcttgataca actcgtgtgc gcgatgaagc agatgctcca aaattacttc
    43741 cataccacgg gaaacaggat ggaagtacac ttgcacatac atttgatatc ggctaacgat
    43801 ataatcttcc actgcatgca tgccactcat ggaaaaagcg atcccgcctt cataaggacg
    43861 aatcacacgt aatattcggg taagatcaaa tgttccatat tctgttccag tgaaataagc
    43921 atcccgaagc aaatagtcca ttcgatctgc atcgatctga ctagaaatca tttggacaac
    43981 ttgtgggttg gggtaagttt tttggatcac actagctacc ttttcaggaa aaccttcttc
    44041 tactcggtta agaatctgat acacttctgt ttctggagaa gtgatgatct ctacagtgat
    44101 ggcttcatga ttcgtatgga agatatgttc aaatgtatga gagtaaggac catgaccgac
    44161 atcatgcaac agtgccgcac ataaagtcac cagccgttcc tgatcatccc agcctccgtt
    44221 gcctattttt tcttttgaaa aatttcgaga aaagatatcg cagattcgtc ttgaaatctc
    44281 ataaacgcct aatgaatgag taaaacggct atgttctgct ccgtgaaaag tgaaagaaga
    44341 agtgcctaat tgtttaatgc gtcgtagacg ttggacttct ttcgaattga tcaaatctaa
    44401 gattacttga tgctggacat ggatatagtt atggactgga tcacgaaaaa ctttttccat
    44461 aggcagcatt tgatatttat aaggggttgt cataatgtag ctcctttatg ttattacgtt
    44521 gttccattct ctggatttgg ttgttccatt gctccagctg gatttctttt tttagccagt
    44581 cggtagaatc ctgtaaatca cttgcagaat acagcttttc aaaagctttt gcaaatgctt
    44641 ctttgacttc ttttacaaaa aggggttggt caagcagttc ttcaagtgtt gccattgtag
    44701 caggatccac tgcaggatag ccatttgtac caaagtcttc ttttaaagca gattgataaa
    44761 atcgcttcat gacttgccca cgtttttcct gattaccgtt gacacttaag tacatcataa
    44821 cagaaatccc atttttgatc cgacgctgag cgataccggc aaattttttg ccatggatgc
    44881 ttaaatcata agttccagga caataagaat gggtgatttc gaatgcttgt atcggtgcct
    44941 ttggaaaagc gtatttagtc aataggagca tttgctcgta agcgtcatct atggttattt
    45001 tttttgtgtc actttggggg aaaatcaaag aaatattcaa aattccttca tctgatacga
    45061 tccctaatcc acctgaattt ctgatcactg gagcgtaacc tgcatcttcc agtgtttgga
    45121 tcccgtcact tagaaaagga gttcgaacat ccttcatacc taagatgact gtgcagtcat
    45181 attgccagaa atgtaaaaag atttgctggt gttctttaga atattccgtt aatatatctg
    45241 ttaatgcaaa aggggaaaag tcgttttttt gataaatgtg ctgatctagt cgaatcgcag
    45301 ggttcattca accggctcct ttgtataaat tcatattttc tacaatatta tactctaaaa
    45361 tcaaagagtt gttttggaaa aaaggttttc tgtaaaaatg gacaagttgg ttgacaaaac
    45421 aaaagaaact aggaacaatg tagctatgag aagtaaagga gaatgaataa tggaattatc
    45481 acaaggaaca ccgatttcaa tcaaattgcg tacaaaagta aaacagcaag gggaagtgca
    45541 agatttttat tttgatttga aagggcaaat ggtgacaatt ggcgatacgc tgtacatacg
    45601 ttataaagag attcaggagg agacgggcga tgagattcct gtaacgatca aattagttcc
    45661 agatggtcat gtacagctga tccgtgcagg agaaatgcgg atgcgtttga aatttggcta
    45721 taaagaacgg ttagaaacat cctatcgaac accatacggt atgatccaga ttgctacttt
    45781 tacgaaagaa ctgcatgtta gtttgaaaga ccgtcccaca gcagggaagg ttcgaatcga
    45841 ttatgatctg ttcatgggac cggaaaaaat cggcgaatat tatttgacct tggattttac
    45901 agcgtaaata taaaagaaaa gtttgatttt ttgtgtctga ttttgtatga taaggagtag
    45961 actgtgaaag gacgtgtcct gattggaaat tagtgtattt gaaggtgcaa acaaaagcga
    46021 attatcaatg atcgaagtag cacacgcgat cttagaacaa cgtggcgatg tcatggattt
    46081 ttctgattta gctaaccaga tccaaaacta tcttgggaaa tcagacagtg aaattcgtga
    46141 ttcactcgca caattttata ctgacttgaa tattgacggc agctttatct cattagggga
    46201 taatcgttgg ggcttgcgtt catggtatgc tatcgattcg atcgatgaag aagtaaacca
    46261 tggaatggac gaagaggatg aagatactcc acgtcgccgt aaacgcaaga aagtcaacgc
    46321 ctttatcaat gatgatgaag acgcgatcga ttacaatgac gatgacccag aagatacaga
    46381 tctgacagaa gaagatgacg atgatctgtt tgatgacgat gatgatgaag atgaagaaat
    46441 cgctgcttat aattctgact tgcaagaaat cggagcagat gacccgacag atgatgaaga
    46501 agacttgcca ggaaatatcg aagaagattt aagtatcata gacgaagacg atgatgatga
    46561 agattatgaa gaggaagaat tttctgactc tgaaaaagaa taaacattat tttcttacga
    46621 gaggttgtga cagagacgat cagcctatca gaataaggag gtgtgacacg atttttgtca
    46681 caccttcttt tttgtatata aaaatcccaa gtaaatacat aaaaaataaa aaaattgaaa
    46741 cttttagcgc accttgtacg tcatattaag tgaggcagaa aggagtggag aatgattttt
    46801 actggatata agaaaaaacg gcagatcgaa aaataccgtc acctgctgaa tggactcatc
    46861 gaaactgatt atcaaaaaat gttccgtatc acgatgaatt acgtacatga taaagaagag
    46921 gccttagatg tgatgcaaga tagttttcat aaagccctga actattttga aaaagaaaaa
    46981 gagatcgagc attttagtgc atggttttat cggatattga tccgcacggc attagatagt
    47041 tggcgcagac aaaaaaggac gcctgtggac ttatttgaaa ttcaagatat cccccaacag
    47101 ttacctttag aaacttccgt tgcagagctc catatgattt tagataaaat agacagtccg
    47161 gaaaaagaga ttctgatcct ctactttttt gaaggatttc gtttgaaaga aattgcgact
    47221 atcttggata tgaatgaaaa cacagttaaa acgaaaatgt accgctcatt gaatgcttta
    47281 cgtcaaatcc tagaatgaag gagagaagag tgccatgtat tcccaaaaag aaaatttaaa
    47341 aaaactaaag aaaacttata aagaacaagc aattcccaaa gggcttaaag aggagatccg
    47401 ccagcgtttt attatcgaag agcaatcatt tataaaagca aagcggagaa agagacgtct
    47461 ccaagggttc ggagtatctt tggctatcgt aatgattaca acaagtagcc ttctttttaa
    47521 tagtcaagtt cgaagctttg cagaagattt acccatctta ggatcagtca ttgaattgat
    47581 cttaggcgaa cgctttactg atcgatctga aaaaatcgat attcaggtac cgaagatcaa
    47641 tacacaaaat gagaaagaaa ataaaacaat tcatggatta aatcaaaaat actttcgcga
    47701 aggacaagca gattttgaaa aagctgaaaa agaatatgga aattttgaaa cggatcatta
    47761 ccaagttttg ggagattatc agaaaatcgt agacgataac cggtttctcg tgattgaaag
    47821 gcagatcacc caaacagcag cagatagcca tgttgaaaaa agatacgaca caatcgacaa
    47881 gaaaaacagt gtccagctct cacttccact tttattcaaa gatgacacct atctatctgt
    47941 tttgacaaaa gaagtcaaac ggcagatggc cgaacaagtc aaggaagatc catctaagta
    48001 ctattggact gagcaagata ttcaagaagg gacgatagaa aaaccaacac ttgttacgcc
    48061 tacacgaagt ttttatttga acaaagagca tcaattagtt ttgacttttt ctcaatacga
    48121 aattgctcct ggttatatgg gtacaccaga atttgtcatt cctaagtccg tgacaaaaac
    48181 gattttggca tcggaagatt atttggatca ttagacgaga agtagttgcg actagcagtt
    48241 tcaattttca agtaagtaca agtaaataat aagaagagaa aaagagaaag aagagatata
    48301 gtgaaaagaa attatttagt tatcagtatt attgctttat ccgtgctttt gtttttcgaa
    48361 attacttcgg tggcctcctt gatcaccgaa gtaaaaggac aaacacactc ttcggagcat
    48421 tcgtcacaat ctttcaaaca atcagaacaa tcaaccatta aaagccaatc aactgaaaca
    48481 gctaacgtca aagaagccat tcaagaatca gcggaaaagg tacaaagtca gtcatcacaa
    48541 tcaacacaag acagtacaaa aacgagccga gatccggctg tcaaaagcgt cgcaatcagc
    48601 tttgatgatg gaccaggagc gaccacaaca ccgcagcttc tgcgaatctt aaaagaaaaa
    48661 aacgtgcatg ccactttttt cgtcttagga gaaaatacgg cgcagcatcc tgaaatcgtg
    48721 aagcagacag ctgaagcagg gcacgagatt ggcaatcaca catacgatca tcagaatctg
    48781 gccactcttt ctgcccagtc gatgacggag gaagtgacga aagcagacac tgagatcaaa
    48841 aaagtcactg gcaaaacccc cacttttgtt cgtccgccct atggttctgt cacgaatgta
    48901 ggagcaacga tcatccagcg accgatcatc gaatggtctg ttgattcaga agattggaag
    48961 acaagaaatc ctgatttgat tttgcagaag atccaagcaa cagtatacga tggggcaatt
    49021 attttattcc atgatatcta tcctgaaacg attcgtgccg ttcctcaagt gatcgattat
    49081 ctgaaagagc aagggtatcg catcacgaca gttggggatt tattagggca tccaacggct
    49141 gtcgagaact attatggcag aaacgatcat cggccagttc agtaagtgag acaagtatct
    49201 ttaataaata acacatttta ataagtagtt gaacacataa ctaccttact tgcaaaggct
    49261 taacaatatc tatacaggta caacaaaaaa ctgtccacca attttctttg gcggacagtt
    49321 ttcacttaaa aataaagaag caactattcg taaattatgc taaaatagca gtagaacgcg
    49381 tcctgaggga atcgaacccc cgtctcaaga accggaatct tacgtgatat ccactacact
    49441 aaggacgcaa gcactgggat aattgtaact aaacagataa aaaattacaa ggggattgga
    49501 caaaaaaatg aaatttgagc aaaatttttc acaaaaacag cagcagacac agaaactagc
    49561 catgacgcaa cagttgcaac agtccatcca agttttacaa tataacagtg aggagctgtt
    49621 ggcattcgtt gagaatcaag caatggaaaa tccattggtg gaagttgttg agccggaatg
    49681 gcagccagat tacataaaag cttcttcatc ttcttatgaa ggagaagaga caaattacct
    49741 aaatcagatt cctgatacaa aagggtcttt atttgattca ttgatcgaac aagtccattt
    49801 gaattaccga gatacttttt tgaggaaaat cgttctttat cttgtagaat acatcgattt
    49861 gaacggattt ttgacgatta gtttagaaga agccggaaaa gagattggag ctacgcctat
    49921 ccaaatgctc gatgcgttga ctctgattca gcaattagaa ccagctggag taggtgcacg
    49981 tagtttgcaa gaatgtctca tgcttcaaac agaacgagat gattatgcgc cggaattagc
    50041 ttatatcgtg ttggaagaat gttttgagga actggtggag cgaaaatgga aagaaatcgc
    50101 acaacgtttt tctgttgatc tacatgctgt tcagcagata ttcgactatt tacaaacgtt
    50161 gagtccaagc cctggccgga ttttcgaccg tagcagcgaa ttgtacatta ttcctgatgt
    50221 ccgggtatta gtggacgacg ataaaaatgt acaagttatc tcaaaccgaa aaaatcagcc
    50281 aaatatacgc tttcaagaga gttacttcaa acaaatgtca caacaagcag ataaagaaac
    50341 tgaaaattat ttaaaagaac ggaaacagga attcgaatgg ttgaagaaaa cgatcctaca
    50401 acgtggggat acaattttgc gggttgctca agtcattgtt tcccggcaaa aagctttctt
    50461 tatcgacaag gaacgtccaa tcaagcctct tacgttaaag gaagttgcaa ctgagataga
    50521 tgtgcatgaa tccacggtca gtcgtgcagt caacgggaaa tatttggaaa cagacttcgg
    50581 tgtatttgaa ttaaaaaaat ttttcactac acgaattcct acgaatagta cagaacagac
    50641 agaagacctt tcagcagata cagcgaagaa aaagctgcag gaattagtcg atcaagaaga
    50701 caaaaacaag ccgttgtctg accagaaatt ggttgaattg ctgaaaaaag atgagatagc
    50761 gatctcaaga cgaacagtag caaaatatcg tgatttatta ggaatcccga gttcatcaaa
    50821 aagaaaacgt tatgataact aatcagtcaa aagactagaa aaagtatttc actttttcta
    50881 gtctttttag ttgaaaaacg agagcaaaac tgttagactt acagtcgtga ggttgagatt
    50941 tccctttatt gatgtgaaat tcgaatagtt aatttctttt tttatcgtat atgggtcgtt
    51001 ttaagtctac attggacgta aagtgtccaa ctaaggagat cgctatgctg gatgaaataa
    51061 aaatgattga atctgttgca ccagatatta tcgaagtgtt gcaagaacgc tataaaattt
    51121 tacgaaatat ctattggatg cagccgattg gacgtcgaag tttatcggaa agtatgggga
    51181 tcacagaacg agtattgcga acagaaacag atcttttgaa aaatctgaat ttgatcgaca
    51241 cctcaaaaag cggtatgacg ctgacaacta agggcgaaga agtttatcaa agccttgaaa
    51301 acttcatgga tcagctttta ggtacgcatc aaaccgaaca acagttggca gaatattttg
    51361 gtaaccaacg ctgtatcgtt gtttcaggaa acagcgaaga gcagaccaaa gtggctgatg
    51421 cattcggcga agcgctgagc gaagccctag accgactact tccagaaggc gagaatatca
    51481 tcgctgtgat gggaggaact actatggctg tggtagccga acaattgtct aatctggaaa
    51541 ataagaaacg gcataacctg tttgtccctg caagaggcgg gattggtgaa gcgataactg
    51601 tacaggcaaa ttctgtcagt gcaagaatgg ctgctaaagc aaacggtaac caccgtgcac
    51661 tttatgttcc ggaacaatta agtctggcaa cttacaattc tttactcaat gagccatcta
    51721 tccaagaagt cttaaacttg attagtgaag cgaattgtgt tattcatagt attgggcgtg
    51781 cattacacat ggcagcacgt cgtaagatga ctgaaaaaga attagtcatg ctgaaacaag
    51841 caaatgctgt tgcggaatct tttggctact ttttcaatga aaaaggtgaa gtcgtttata
    51901 aggtccctag aatcggcata gaattgcaag atttggaaaa agtcccgatc atcatggcaa
    51961 tcgcgggcgg aaaatcaaaa gctaaagcaa ttcgagctta tatgaaaaat gcaccaaaac
    52021 aaacgtggct catcactgat gaagctgctg caaatgagat tttaaaaggg gtaacccttt
    52081 aaaataaata tttttttgat tttcataagg aggaaatctt aaatgacagt taaagtaggt
    52141 attaatggtt ttggacgtat tggacgtcta gcattccgtc gtatccaaga tgtagatgga
    52201 atcgaagtag tagcaatcaa cgacttgaca gatgctaaaa tgttggcaca cttgttaaaa
    52261 tacgacacaa ctcaaggacg tttcaacgga acagttgaag ttcatgaagg ttcattcaac
    52321 gtaaacggaa aagaagttaa agtattagct aaccgcaacc cagaagaatt accatggggc
    52381 gaactaggcg tagatatcgt tctagaatgt actggtttct tcacttctaa atcagcagct
    52441 gaaaaacatt taacagctgg tgctaaacgc gttgttatct ctgctcctgg cggaaacgat
    52501 gttccaacaa tcgtttataa cacaaaccac gaaacattaa ctggtaaaga aacagttatc
    52561 tcaggtgctt catgtactac taactgttta gctcctatgg ctaaaacatt gaacgacaaa
    52621 tttggtgttg ttgaaggatt aatgacaact atccacgctt acacaggtga ccaaatgact
    52681 ctagacggac ctcatcctaa aggtgacttc cgccgtgcac gcgctgctgc tgcaaacatc
    52741 gttcctaact caacaggtgc tgctaaagct atcggtttag taattcctga attgaacggt
    52801 aaattagacg gagctgctca acgtgttcct gtaccaacag gttcattaac agaattagta
    52861 acagttcttg aaaaagaagt aactgttgac gaaatcaatg cagcaatgaa agaagcttca
    52921 aacgaatctt acggatacaa cacagacgaa atcgtttctt cagatatcgt tggtatgact
    52981 tacggttcat tatttgatgc tacacaaact aaagtaatga cagttggcga caaacaatta
    53041 gttaaaactg ttgcttggta cgacaacgaa atgtcataca ctgcacaatt agtacgtact
    53101 ttagaatact tcgctaactt ataagataga caaacgtaca agtgtaaatt atagacatgt
    53161 acatttaaaa gcggggaagc aatcgcgctt cttccgcttt ttttgataat aagtttattc
    53221 aggaggaaat aaaatggcta agaaaacagt gaaagatatc gatttaaaag acaaaaaagt
    53281 tcttgtccgt gttgacttca acgttccttt gaaagacggc gtgatcactg acgacactcg
    53341 tatcaaagca gcattgccaa caatcaacta cgttctagaa caaggcggaa aagcaatcct
    53401 tttctctcac cttggacgtg taaaaacaga agaagataaa gaaggaaaat ctttagctcc
    53461 agttgcaaaa cgtctaggcg aattattagg taaagaagta acattcgtac ctgaaactcg
    53521 cggagaacaa ttagaagaag caatccgcaa catgaatgac ggcgacgttg tcgtattcga
    53581 aaatacacga tttgaagata ttgacggtaa aaaagaaagc aaaaatgata cagaactagg
    53641 taaatactgg gcttcattag gcgatgtatt tgttaacgat gctttcggta cagctcaccg
    53701 tgcacatgct tctaacgtag gtatcgcttc aactggtatc ccaacagttg ctggattctt
    53761 gatggaaaaa gaaatcaagt tcatcggtga agcagtagaa gaaccaaaac gaccaatgat
    53821 tgcaatcctt ggtggcgcaa aagtttctga taaaatcggc gtaatcgaaa acttgattcc
    53881 taaagcagat aaaatcttga tcggtggcgg aatgacttac acattctacg aagcaaaagg
    53941 aatcaagatc ggtaactctc tagtagaagc tgataaagtg gaactagcaa aagaattaat
    54001 cgaaaaagca ggcgacaaac ttgtcttgcc aatcgacaat gtctgtgcac cagaattttc
    54061 aaatgatgtt gaaacacaag taatcgaagg agacattcct gatggtttga tggctttaga
    54121 catcggccca gcatcagtaa aattatttgc tgatacatta caaggtgcaa aaacagttgt
    54181 ttggaacgga cctatgggtg tatttgaaat gagtaacttt gctaaaggta caatcggtgt
    54241 ttgtgaagca atcgctaact tagaaggcgc aacaacaatc atcggtggcg gagactcagc
    54301 tgcagcagca gaacaattag gatttgctga caaattcaca cacatctcaa caggtggtgg
    54361 cgcaagcttg gaattgcttg aaggtaaaga attaccagga ctagcagcaa tcaacgataa
    54421 ataaacgacc aagtttgctc aattctgacg agtaatcgat caaaaggtga agggagtttt
    54481 catgactccc tagccatttt tcaataaatt aaggagtgtg ttcctcaatg cgtaaaccta
    54541 ttatcgcagg taactggaaa atgaacaaaa ctgcatcaga agcaaaagaa tttgctgaag
    54601 cagtaaaaaa caaaatccct tcaaatgaca aagttgattc agtcatcgga tctcctgcat
    54661 tattcttaca agaattaatg acatcagctg aaggtacaga actaaaaatc tcagcacaaa
    54721 actgctactg ggaaaactca ggtgcgttca ctggtgaaac ttcaccagca gctcttgctg
    54781 atctaggtgt tcattatgtg atcatcggac attcagaacg tcgtgaatat ttccatgaaa
    54841 cagacgaaga catcaataaa aaagcaaaag ctatctttgc aaatggtatg acaccaatcc
    54901 tatgctgcgg cgaatcttta gaaacctatg aagcaggcaa aactgctgaa tggatcgaag
    54961 gacaaattac agctggttta gctgatcttt cagctgaaca agtgtcaaac atggttattg
    55021 cttatgaacc aatctgggca atcggtactg gtaaatcagc tgacgcacaa atcgctgacg
    55081 aaatttgtgg agttgtacgt caaacagttg aaaaacttta tggaaaagaa gtatcagaag
    55141 cagttcgtat ccaatacggc ggttctgtaa aaccagaaaa tattgctgaa tacatggcaa
    55201 aagaaaatgt tgacggtgct ttagtcggtg gcgcaagctt gcaagcagat tcatttttgt
    55261 cattgttaga cgctgtaaaa taattgttga aaatttgcga aaaatgcaag aaatgtttgc
    55321 actaatgagc aaaattaact aaaatcgtat atgagggaaa tcccttagga aaaaacaaac
    55381 tcaaaggaga gacaaaacat gtcaattatt actgatgttt acgctcgcga gatcttagac
    55441 tcacgtggta acccaacaat cgaagtagaa gtatacacag aaagcggagc ttttggccgc
    55501 ggaatggttc cttcaggtgc ttcaactggt gaatacgaag cagttgaatt acgtgacgga
    55561 gacaaagctc gttatggcgg taaaggtgta actaaagctg tcgacaacgt aaacaacatc
    55621 attgctgaag caatcattgg ctacgatgtt cgtgaccaaa tggctatcga caaagctatg
    55681 atcgctttag acggaactcc taacaaaggt aaattaggtg cgaacgctat tttaggtgtt
    55741 tctatcgctg ttgcacgtgc agctgctgac tacctagaag tacctttata ccactaccta
    55801 ggcggattca acacaaaagt attgccaaca ccaatgatga acatcatcaa cggcggatca
    55861 catgctgata actcaatcga cttccaagaa ttcatgatca tgcctgttgg cgctccaaca
    55921 ttcaaagaag ctctacgtat gggtgctgaa gtattccacg cattagcttc aatcttgaaa
    55981 gctcgcggat tagcaacttc tgttggtgac gaaggtggat ttgctccaaa ccttggttca
    56041 aacgaagaag gttttgaagt aatcatcgaa gcaatcgaaa aagctggcta tgtacctggt
    56101 aaagacgttg ttcttgctat ggatgctgct tcttcagaat tctacgacaa agaaaaaggt
    56161 gtttacgtac tagctgactc aggcgaaggc gaaaaaacaa ctgacgaaat gatcaaattc
    56221 tacgaagaat tagtttctaa atatccaatc atctcaatcg aagatggatt agacgaaaac
    56281 gactgggacg gattcaagaa attaactgac gtattaggcg acaaagttca attagttggt
    56341 gacgacttgt tcgtaacaaa cactcaaaaa ttatctgaag gtatcgaaaa aggaattgct
    56401 aactcaatcc ttatcaaagt gaaccaaatc ggtacattaa cagaaacttt cgaagctatc
    56461 gaaatggcta aagaagctgg ctacacagca gttgtatctc accgttctgg tgaaacagaa
    56521 gattcaacaa tctctgatat cgctgttgca acaaatgctg gccaaatcaa aactggttct
    56581 ctatcacgta ctgaccgtat tgctaaatac aaccaattac tacgtatcga agaccaactt
    56641 ggtgaagttg cagaatacaa aggtttgaaa tctttctaca acttaaaaaa caaataattc
    56701 ttttctaatg aagatacatg atcgactatt gaaagatagt cgagtatgat cacttagtta
    56761 agtaatcgaa ctctctactt gctgaaatat cagcaggtag aga
//
LOCUS       DAPBBR010000014        56387 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPBBR010000014 DAPBBR010000000
VERSION     DAPBBR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.014"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            330..1175
                     /locus_tag="RD488_000860"
     CDS             330..1175
                     /locus_tag="RD488_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7656955.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="RD488_000861"
     CDS             1456..2676
                     /locus_tag="RD488_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HDT7656956.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="RD488_000862"
     CDS             2673..5393
                     /locus_tag="RD488_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7656957.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="RD488_000863"
     CDS             5377..6321
                     /locus_tag="RD488_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7656958.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="RD488_000864"
     CDS             complement(6390..7400)
                     /locus_tag="RD488_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7656959.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="RD488_000865"
     CDS             complement(7580..7924)
                     /locus_tag="RD488_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7656960.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="RD488_000866"
     CDS             complement(7917..8351)
                     /locus_tag="RD488_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDT7656961.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="RD488_000867"
     CDS             8489..9226
                     /locus_tag="RD488_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7656962.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="RD488_000868"
     CDS             9219..10430
                     /locus_tag="RD488_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7656963.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="RD488_000869"
     CDS             10634..11416
                     /locus_tag="RD488_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDT7656964.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="RD488_000870"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="RD488_000870"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDT7656965.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="RD488_000871"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="RD488_000871"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDT7656966.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="RD488_000872"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="RD488_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDT7656967.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="RD488_000873"
     CDS             15018..16067
                     /locus_tag="RD488_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HDT7656968.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="RD488_000874"
     CDS             16064..16342
                     /locus_tag="RD488_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDT7656969.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="RD488_000875"
     CDS             16317..16787
                     /locus_tag="RD488_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDT7656970.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="RD488_000876"
     CDS             16804..17106
                     /locus_tag="RD488_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656971.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="RD488_000877"
     CDS             17123..17494
                     /locus_tag="RD488_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HDT7656972.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="RD488_000878"
     CDS             17466..17825
                     /locus_tag="RD488_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656973.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="RD488_000879"
     CDS             17997..19004
                     /locus_tag="RD488_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7656974.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="RD488_000880"
     CDS             19029..20213
                     /locus_tag="RD488_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDT7656975.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="RD488_000881"
     CDS             complement(20650..22233)
                     /locus_tag="RD488_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7656976.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIRTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="RD488_000882"
     CDS             complement(22811..22954)
                     /locus_tag="RD488_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HDT7656977.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="RD488_000883"
     CDS             complement(23177..23656)
                     /locus_tag="RD488_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7656978.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="RD488_000884"
     CDS             complement(23729..24013)
                     /locus_tag="RD488_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7656979.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="RD488_000885"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RD488_000885"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="RD488_000886"
     CDS             complement(24357..25643)
                     /locus_tag="RD488_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDT7656980.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="RD488_000887"
     CDS             25781..26452
                     /locus_tag="RD488_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDT7656981.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="RD488_000888"
     CDS             26418..26906
                     /locus_tag="RD488_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HDT7656982.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="RD488_000889"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="RD488_000889"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDT7656983.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="RD488_000890"
     CDS             27867..28631
                     /locus_tag="RD488_000890"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDT7656984.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="RD488_000891"
     CDS             28864..31077
                     /locus_tag="RD488_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDT7656985.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="RD488_000892"
     CDS             31088..31534
                     /locus_tag="RD488_000892"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDT7656986.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="RD488_000893"
     CDS             31705..32964
                     /locus_tag="RD488_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HDT7656987.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="RD488_000894"
     CDS             complement(33053..34000)
                     /locus_tag="RD488_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7656988.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="RD488_000895"
     CDS             34394..35686
                     /locus_tag="RD488_000895"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDT7656989.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="RD488_000896"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="RD488_000896"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDT7656990.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="RD488_000897"
     CDS             37579..38454
                     /locus_tag="RD488_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7656991.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="RD488_000898"
     CDS             38720..40603
                     /locus_tag="RD488_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7656992.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVMGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="RD488_000899"
     CDS             complement(40678..40962)
                     /locus_tag="RD488_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7656993.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="RD488_000900"
     CDS             complement(40952..41686)
                     /locus_tag="RD488_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDT7656994.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="RD488_000901"
     CDS             41815..42438
                     /locus_tag="RD488_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDT7656995.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="RD488_000902"
     CDS             42630..43751
                     /locus_tag="RD488_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDT7656996.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="RD488_000903"
     CDS             43758..46886
                     /locus_tag="RD488_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDT7656997.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="RD488_000904"
     CDS             46905..50099
                     /locus_tag="RD488_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HDT7656998.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="RD488_000905"
     CDS             complement(50245..50952)
                     /locus_tag="RD488_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7656999.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="RD488_000906"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="RD488_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7657000.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="RD488_000907"
     CDS             52447..53100
                     /locus_tag="RD488_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDT7657001.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="RD488_000908"
     CDS             53326..54324
                     /locus_tag="RD488_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDT7657002.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="RD488_000909"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="RD488_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDT7657003.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18554 a         9727 c        11686 g        16420 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcggac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ctgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt gatgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttt
//
LOCUS       DAPBBR010000015        56361 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPBBR010000015 DAPBBR010000000
VERSION     DAPBBR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.015"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            209..787
                     /locus_tag="RD488_000910"
     CDS             209..787
                     /locus_tag="RD488_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7657004.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            787..1716
                     /locus_tag="RD488_000911"
     CDS             787..1716
                     /locus_tag="RD488_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657005.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            1713..3449
                     /locus_tag="RD488_000912"
     CDS             1713..3449
                     /locus_tag="RD488_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7657006.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(3512..4348)
                     /gene="pheA"
                     /locus_tag="RD488_000913"
     CDS             complement(3512..4348)
                     /gene="pheA"
                     /locus_tag="RD488_000913"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDT7657007.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(4345..4854)
                     /locus_tag="RD488_000914"
     CDS             complement(4345..4854)
                     /locus_tag="RD488_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDT7657008.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(4847..6142)
                     /gene="aroA"
                     /locus_tag="RD488_000915"
     CDS             complement(4847..6142)
                     /gene="aroA"
                     /locus_tag="RD488_000915"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDT7657009.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(6155..7246)
                     /locus_tag="RD488_000916"
     CDS             complement(6155..7246)
                     /locus_tag="RD488_000916"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDT7657010.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(7263..8429)
                     /gene="aroC"
                     /locus_tag="RD488_000917"
     CDS             complement(7263..8429)
                     /gene="aroC"
                     /locus_tag="RD488_000917"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDT7657011.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(8431..9495)
                     /gene="aroB"
                     /locus_tag="RD488_000918"
     CDS             complement(8431..9495)
                     /gene="aroB"
                     /locus_tag="RD488_000918"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDT7657012.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(9528..10550)
                     /gene="aroF"
                     /locus_tag="RD488_000919"
     CDS             complement(9528..10550)
                     /gene="aroF"
                     /locus_tag="RD488_000919"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDT7657013.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(11209..12183)
                     /locus_tag="RD488_000920"
     CDS             complement(11209..12183)
                     /locus_tag="RD488_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HDT7657014.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(12164..14047)
                     /locus_tag="RD488_000921"
     CDS             complement(12164..14047)
                     /locus_tag="RD488_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HDT7657015.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(14065..16290)
                     /locus_tag="RD488_000922"
     CDS             complement(14065..16290)
                     /locus_tag="RD488_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDT7657016.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            16405..17439
                     /locus_tag="RD488_000923"
     CDS             16405..17439
                     /locus_tag="RD488_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7657017.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(17506..18519)
                     /locus_tag="RD488_000924"
     CDS             complement(17506..18519)
                     /locus_tag="RD488_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7657018.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(18597..18785)
                     /locus_tag="RD488_000925"
     CDS             complement(18597..18785)
                     /locus_tag="RD488_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDT7657019.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(19225..19353)
                     /locus_tag="RD488_000926"
     CDS             complement(19225..19353)
                     /locus_tag="RD488_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7657020.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(19356..20729)
                     /gene="rlmD"
                     /locus_tag="RD488_000927"
     CDS             complement(19356..20729)
                     /gene="rlmD"
                     /locus_tag="RD488_000927"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7657021.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(20840..21895)
                     /locus_tag="RD488_000928"
     CDS             complement(20840..21895)
                     /locus_tag="RD488_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7657022.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(21905..23335)
                     /gene="gatB"
                     /locus_tag="RD488_000929"
     CDS             complement(21905..23335)
                     /gene="gatB"
                     /locus_tag="RD488_000929"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDT7657023.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(23332..24804)
                     /gene="gatA"
                     /locus_tag="RD488_000930"
     CDS             complement(23332..24804)
                     /gene="gatA"
                     /locus_tag="RD488_000930"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDT7657024.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(24804..25109)
                     /gene="gatC"
                     /locus_tag="RD488_000931"
     CDS             complement(24804..25109)
                     /gene="gatC"
                     /locus_tag="RD488_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDT7657025.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(25215..27251)
                     /gene="ligA"
                     /locus_tag="RD488_000932"
     CDS             complement(25215..27251)
                     /gene="ligA"
                     /locus_tag="RD488_000932"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDT7657026.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(27268..29502)
                     /gene="pcrA"
                     /locus_tag="RD488_000933"
     CDS             complement(27268..29502)
                     /gene="pcrA"
                     /locus_tag="RD488_000933"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDT7657027.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            29657..31216
                     /locus_tag="RD488_000934"
     CDS             29657..31216
                     /locus_tag="RD488_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HDT7657028.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(31327..33258)
                     /locus_tag="RD488_000935"
     CDS             complement(31327..33258)
                     /locus_tag="RD488_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7657029.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(33276..34190)
                     /gene="pfkB"
                     /locus_tag="RD488_000936"
     CDS             complement(33276..34190)
                     /gene="pfkB"
                     /locus_tag="RD488_000936"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDT7657030.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(34187..34939)
                     /locus_tag="RD488_000937"
     CDS             complement(34187..34939)
                     /locus_tag="RD488_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7657031.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(35098..35307)
                     /locus_tag="RD488_000938"
     CDS             complement(35098..35307)
                     /locus_tag="RD488_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657032.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(35318..36646)
                     /locus_tag="RD488_000939"
     CDS             complement(35318..36646)
                     /locus_tag="RD488_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657033.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            36782..36937
                     /locus_tag="RD488_000940"
     CDS             36782..36937
                     /locus_tag="RD488_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657034.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(37011..37598)
                     /locus_tag="RD488_000941"
     CDS             complement(37011..37598)
                     /locus_tag="RD488_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDT7657035.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(37681..38931)
                     /gene="clpX"
                     /locus_tag="RD488_000942"
     CDS             complement(37681..38931)
                     /gene="clpX"
                     /locus_tag="RD488_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDT7657036.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(39178..40467)
                     /locus_tag="RD488_000943"
     CDS             complement(39178..40467)
                     /locus_tag="RD488_000943"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDT7657037.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(40621..41553)
                     /locus_tag="RD488_000944"
     CDS             complement(40621..41553)
                     /locus_tag="RD488_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657038.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHQVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(41710..42369)
                     /locus_tag="RD488_000945"
     CDS             complement(41710..42369)
                     /locus_tag="RD488_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7657039.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(42372..43397)
                     /gene="sppA"
                     /locus_tag="RD488_000946"
     CDS             complement(42372..43397)
                     /gene="sppA"
                     /locus_tag="RD488_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDT7657040.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(43410..43700)
                     /locus_tag="RD488_000947"
     CDS             complement(43410..43700)
                     /locus_tag="RD488_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657041.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            44109..45914
                     /gene="glmS"
                     /locus_tag="RD488_000948"
     CDS             44109..45914
                     /gene="glmS"
                     /locus_tag="RD488_000948"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDT7657042.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(45986..47341)
                     /locus_tag="RD488_000949"
     CDS             complement(45986..47341)
                     /locus_tag="RD488_000949"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDT7657043.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(47365..48534)
                     /locus_tag="RD488_000950"
     CDS             complement(47365..48534)
                     /locus_tag="RD488_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657044.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(48531..49418)
                     /locus_tag="RD488_000951"
     CDS             complement(48531..49418)
                     /locus_tag="RD488_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDT7657045.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(49607..53299)
                     /gene="nifJ"
                     /locus_tag="RD488_000952"
     CDS             complement(49607..53299)
                     /gene="nifJ"
                     /locus_tag="RD488_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDT7657046.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            53498..54019
                     /locus_tag="RD488_000953"
     CDS             53498..54019
                     /locus_tag="RD488_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7657047.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(54718..55275)
                     /locus_tag="RD488_000954"
     CDS             complement(54718..55275)
                     /locus_tag="RD488_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657048.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(55454..56065)
                     /locus_tag="RD488_000955"
     CDS             complement(55454..56065)
                     /locus_tag="RD488_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657049.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(56178..>56361)
                     /locus_tag="RD488_000956"
     CDS             complement(56178..>56361)
                     /locus_tag="RD488_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657050.1"
                     /translation="NSVAINTNAIIFNPATVNLSAYELDSNTYTANMVAYVVEGDALN
                     VVFGGVYTYWRINHVR"
BASE COUNT        15477 a        12204 c        10088 g        18592 t
ORIGIN      
        1 gaaaacggtt tctttattat tcagatactt caaaaatttc tcctaaaata ataaaaaaat
       61 acaaatcaac tatgacaaaa ggaataatct tagcatctag accaaagatc gaaatggtga
      121 ggtttcttta aaataaaaat atccttgcat tttctcctag aaataagtat ttttaaatta
      181 caagactatt cttaaggcgg gtaaaaaaat gccaatacgc gtaattctta tcgatgatga
      241 acagacgatt ttagatggaa tgaaacagtt gatcaattgg tctgagcacg ggtttcaatt
      301 aatagggact ttttccagtc cgctgaaagc gcttgatttt tctttggtac atgcaatcga
      361 tatcgtggtc acagatgtaa tgatgcctga attaaatgga atcgaattat cgcggctatt
      421 aaaacagcaa caacctgaaa cacagatcct tatcctctct agctatgatg aatttgatat
      481 ggttaaagat tcttttaaag aaggcgtcgc tgattatctt ttaaagcctc gattgagtcc
      541 tgattttttt ctaaattcct taactgccgt ttcacaaaaa atcaaaaaaa agcccaacaa
      601 aagcccaatc accaatcgtt atgagcagat ctgcgagaat ctttcacagc agattgctgg
      661 acaaactcgt ccattgcttg accctcttct ttttgaacac accttgtttt tctgttatat
      721 accgaaaaac ggccattcag ttcaaaacaa ggctctaaac aaaaacagtc gatcacccat
      781 tcattgatgg atagcgacga ttcgtttact atttatcctg tttctacctt ttcggaagaa
      841 tccggctatg taatcaatac tgattccaaa gatacactta ggaagtttgt tcaaaagttt
      901 cgtcaagaag tttttccagg tgattttttt gttgtttctg attcttttgc aatccaagat
      961 atcaatgaaa tattccaaga gatcagaaat tgcaccaaag gacaacgttt ctatcataag
     1021 ggaaagaacc ttgcttatca gcatgaactt cttccgttat taaccaacca cgagcagcaa
     1081 gcaagtagtt atttaacaaa aatcgttcat aaagactacg ctttagctgt caaagaactt
     1141 gagaatttct tcacgacgat attggaacag cctattgatc cagcttattt gaaacatgag
     1201 gcaatcaatc gtttctatgc attactcaac gctttggctg acgagcatgt tgggaatgaa
     1261 gaactttctt tgctcaagat cgcccttcct tctttattag ccgatgctga gtatttcgaa
     1321 gatttttcta ttcttgtcaa agaaacactt gagaaactca cccacttttc tgcaaatgca
     1381 aaaaaagaca atttcgatat cttgactttg atctacgagt tcgtccagga aaattatgag
     1441 aaagaaatca atttacaact tttatccgaa aaatatcatt tttcatatag ctatctctca
     1501 gccatcttta ctgaaaaatt tggtatcaac ttttcaaaat atctaaaaaa agtccgtatc
     1561 agtaaagcca agctcttttt gacggaaaca cggcttactt tgacggaaat ctgtgagaaa
     1621 gtcggctata ccgaactggg ttatttctcc agagttttta aagaagagac aggaatgaca
     1681 ccttctcaat accgtaaagg aacttttgta aaatgagaaa aaaaatcaaa gagcatgaac
     1741 tctttgccaa acttctgttc attttgttca tcggtctttt tctgcaagcc atcgtcattt
     1801 ctttgtttat ttatcatcga tcaagggatg cctatatcca gctgttcaat caatcgaatg
     1861 atgtggtact aaaaaagatt caatctgaat ttgaaagttt gaatgataca atcgagaata
     1921 cattagccgc ttttgattct aatccagctg tcaaaagcta tttttccaat gatccagccc
     1981 aacatatgga acagcttcag caactaagaa caatccaaaa aatgaatgac tctctttcaa
     2041 aaatccatcc aatgatcgat tacgatgtat tgatctttgg agaaaatgga agaacttttg
     2101 tcggaaacga catgctcact gccgtatctg ccgattcttt ttttcaatct gcgattgctc
     2161 agagagtgaa tgaacgtgct gctgatacac aaatgctttt tgcacaccac ggattgactc
     2221 ttcgcgataa gaaagcaccc agcgtcttct ttgtcaaaaa actgaaaaat acattgaatc
     2281 acgtttacgg atatgctgtt ttatcgatct catccaagca actagcgaat ctttttcaat
     2341 ctgtagtaaa tcctgagata tcgaagatct ccttcatgaa cgaagaacag acgatcatcg
     2401 catcaaatga agaaaataca attgggagcc gatcaatgat tttcaaaaaa ctaacagtag
     2461 gtgaaacaac gatttcaaat ggacagcagt tgacccgtct tcctctgtac cgccaggatt
     2521 gtacattact cagtcaagtc gatcttcatt ctttatctaa ccaaatgggc gtgatttttc
     2581 cgattatttt gtataatatc gtgacacttg cttttgctgg ctcattggta tttatgtatt
     2641 tggatcgaca cacaaaatcg atctaccgct tgattgattc gctaaaacgg ctagaggaag
     2701 atggcttaaa agctactgtt cctgtacaag gaagccatga agtccaattg ctagggaata
     2761 cgatcaatca attgctaagt aatgctcagc atcattatga acagacgatc caagacgaaa
     2821 agaagaaacg ttcgcttgaa atccaaacta tgcaagcaca gatacagccc cattttattt
     2881 ataatacgct gactagcttg aaatttttga tttggcagaa aaaaacagat gaagcagttc
     2941 aaggaatcga cagtttcatt actttactaa gaagtacgat tgggaaaaaa gaagaagtga
     3001 ttccagtcaa ggaagaaatc aaaagcgtac aaagttacat cgatcttttg agtatgcgat
     3061 atggcgaaag aatctcggct aaaataatga ttcctgatga actgcagtca ttatctatgc
     3121 cgaatatgat ccttcaacca attatcgaaa acgcctatct tcatgctttt cacaataaaa
     3181 cgcaaggatt catcacggtg tacggcaaaa caaaaaatca gcttctttta ttcgaagtga
     3241 ttgataacgg cgatggcttc gatactgaaa ataccaaaca aaaaaatgat catttttcag
     3301 gaatcggcat cagccatgta gatgagcgga tacgcctaat gtatggcgat gcatatggct
     3361 taacgatcca atcagtgatt gggacaggaa cgactgtaac gatttgtcta ccgcttcttc
     3421 ctaaaaatca atcagaatat caaaaataaa gaatagccaa gcgctgattt ttttatttta
     3481 agttaaataa atcaatcagt attcttgact ttcatctacg cgtctcttct actgtcagca
     3541 ctggataaca gcccaatatt tgactttctc ctccgagcat cttgatttct tggagcgcat
     3601 tctctactaa tgtcattgga cggtccaaca acaaatcgat cacgaaaaaa tattctccca
     3661 agctagtttt caatggtcgg gattcaatct tacttaagtt gatttcccgc cagccaaaag
     3721 ctgccagcat tttatgaagc atccctggcc gattagcagg tagtgtcaag atgacactca
     3781 tttttactgg agctgactgc tggctggtca tctttcggtc accgacgatc caaaaacgtg
     3841 tctggttcaa ctcattatct tggatattct cagctaagat ctccaatcca acatgctgtg
     3901 ctgtttctaa tgaagcaatc gctgctgcgt cttctttcgg atgttctgct acatacattg
     3961 ctgcagcagt tgttgattct gttgctacta aaggaacatt aggataatgc gtttctaaaa
     4021 actgttgtga ttgtgctagt gcttgtggat gtgaaaggat ttttgtaatc tttgttgctg
     4081 gattgcctaa aagctgctgc ttgataggaa gaacgatttc acttttaact tcgacttctg
     4141 gatgtttgga aagaagatcg attgtgtgat gaacagctcc ttccaatgaa ttctctacag
     4201 gaacgacagc cagatcgact tgtttgcgaa acaaagcgcg caaacaaaca gggatggaag
     4261 catacgcagt caattgttct gtaggaaata gctgacaagc cgcctgataa gtgaatgaac
     4321 tttctggccc tagatagctg acgttcatat gcttttgatc ctttctataa tggtatcgat
     4381 gatcttttct ggtgtttgat tggtcgtgtt gattcgatgt gtcgcacttt cttcatacca
     4441 agaaagtcgt tgtgccaata atgcttttat ttcttctctt gtttttccaa gagctaaagg
     4501 tcgaatagac gtttcatctt gttggatacg atcaactaga cagtccgctt ctgcctctaa
     4561 gtaaagaaca atcggctgtg tttttaaaaa acgccgattt tctgcacttt ggacaatccc
     4621 tccaccagtc gcgataattt tgtcttcatt tgacagcttt cttaaaatat ctgactccac
     4681 ttttcgaaag cttttttcac cgtaatagtg aaaatattcg gcaatcgaca attggatatg
     4741 ttcctcaatc tttgtatcta aatctacata ctctttttgt aaacattgag ctaacccttt
     4801 accgattgtt gtttttccag cgcccatgaa accaatcagc aaaatgctag ccatgagctt
     4861 ctcctcctga cacaagttct gctaaatcgt caaaaaatgc cggataagag attgaaacag
     4921 cttcagctcc ttctagttcg caaggtccat cagctatcaa agcagctact tgcagcatca
     4981 taccgattcg atgatcgcct ctgctggaca cttttgcgcc atgcagaggt gtcggcccat
     5041 ggatgatcag accgtctgct gtcgctttta tctttgctcc cattttctgt aattcttctg
     5101 ccaccgcatc aattctgttg gtttctttta cttttaattc ttctgcgtct ttgatgatcg
     5161 tgattccttc tgcttgagta gccactaaag ctagaatggg caattcatca atcagacgcg
     5221 gaatgatttc tccaccaatc gttgctttct tcaaatgact cgtcttgaca cttaaatcag
     5281 ccgattggtt ctgttcattg tgattcgtct gggtaatcgc tgcgcccatc tcctccaaca
     5341 catctaagat accagttctt gttggattga ccccgacatt ttttaacaac agttggcttt
     5401 ccggaacaag aagtcctgct gctagaaaga aagcagctga tgaaatatca cctggaacag
     5461 ttatctgttg accagttaat ttttgcggtc cggtcactat gatcgtttta tcttccactg
     5521 tgatccttcc gccaaattga cgaatcattt cttccgtatg gttacgggaa cgttcttttt
     5581 caacgattac ggatgtgcct tctgcttgta atgccgcaaa cagcaaagca gatttgactt
     5641 gcgcactggc tacaggcata ttgtatcgga taggtgataa agagcgggtt cctgtcacag
     5701 tgattggtag atactggtca ttttcttctc cttgcaagtc agcgcccatc tcgcgtaaag
     5761 gttccatcac tcgccccatt ggacgtttag acaacgaagc atccccgaac agagtagtcg
     5821 taaaaggctg tccagccaaa atacccatca ataaacgtat ggtcgtaccg gagtttccca
     5881 tgtcaattga ttcggttggt tggacaaatg agtggctacc gcgaccatga atcttgatca
     5941 cctcttcctc ttcttcgatc tcgacaccta attgttggaa ggcatgtaaa gtactcagac
     6001 aatcttctgc gcgcaaaaaa ttttgtatag tcgtcgttcc ttcagcaatt gctccaaaca
     6061 tgatgctgcg atgggaaatt gatttatctg ctggtatcct aacagtccct cttaatccat
     6121 gtatttgttg taataattgc atttatccag cctcctattt gatccagcaa tgataactgg
     6181 tattagacat aatgattctt tttgcttgta acaaatcctg ttggttttta aaactgattt
     6241 gcagtattcc taaaatatct tccctggtct cttggatctt caaattaatc aaagaaactc
     6301 ccgcttttcc gatcagtcca gttacttctg caataacgcc aggttcatct ggcacatcga
     6361 taaataaatc aaaaaaggca ggaatcgcgc cttgcttatg gacaggcaac tggtctcgac
     6421 tttcttttgc ccgattgaaa aaagaaaaga tttccgattg gttctcagtc atgatccatt
     6481 ctgctatttg tgtcatttct tgttgccaat ctgccaatcg ttccaataat atctgcttat
     6541 tgctcaacaa aatatctgtc cacatgacag gatctgagga agcgatccta gtgatatctc
     6601 gaaagcctcc tgctgccagt tgtttggctc gcggatactc ttgattgaat tgttctgcct
     6661 gattgactaa gccagctgcc agaatatgtg gaaaatgact tagcattcct gttatacggt
     6721 catgttctct tgctgtaaga gttacatatt ttgctttggt tccgcaaaat agttcttgca
     6781 gtttttcaac atcttttttc gtcttttcca aaggtgtaaa gatgtaatag gcattttcaa
     6841 atagtttagc atctgctgcc tgtatacctg atttatgaga accagccatt ggatgtccac
     6901 cgacaaaccg aagatttttc tgctcagcgg atgtcacgac ttgctgcttc gtactgctga
     6961 catccgtaat gatgacgtga tcagacaagt tgattctttc aaggacatca agataagcta
     7021 aggttgtacg gacgggaacg gctaataaga taacgtctgc ttgttctgca cctgtttcaa
     7081 aatcacttgc aacgtaatca acgatctgct gttctactgc ttgctcacgg gtttttgact
     7141 gactatccca accaactact atcagttctg gattggtctg acgaatacaa agtgccatag
     7201 aagcaccaat cagtccaagc cccacgataa aaacatgttg tgccatctta tttgccccct
     7261 ttttagtaat gtttcaagta gtcacggtac tccttcactg cagctttcaa ctcaacaagc
     7321 gaatcacttg ggaattttga caatagctct gtcgctacca cagtggctac aacattttcc
     7381 gcaacgacgc tagctgcagg aactgctgta ctatccgaac gttctacact tgctttgtaa
     7441 ggttcttttg tatcgatatc aacactttga agtggcttgt acaatgtagg aatgggtttc
     7501 atgaccccgc gaatgacaag tggttcgcca ttggtcattc cgccttcgaa gccgcctaga
     7561 ttattggtac gtcggaaata gcctctttct tcttcccata ggatctcatc catcacttct
     7621 gagcctggta atgaaccaga agtgaatccg accccaaatt ctacgccttt aaaggcattg
     7681 atactaacca cagcttgtgc gattttggca tctagcttcg tgtcccattg tacgtagctt
     7741 cctaatccag ctggaacgcc tccaacgagc acttctacaa ttcctccgat cgtatctcca
     7801 tttttctttg tctgatcgat caaatctttt attctttgct caactgctgg atcaacaact
     7861 cgtacttctg acgcttcaga aatttctttg atttcttgaa tcgagatatt tccaggtatt
     7921 tctgcttgga ttccaccaag acaaatcacg tgtcctgcta cgatgatgtc aagttcttcc
     7981 agaattttct tggcaattgc gccgattgct acacgcatgg tcgtctctct tgcagaggac
     8041 cgttcaagca cattccgaag atctcgatga tggtatttca taccgcctac caaatccgcg
     8101 tgtcctggac gcggacgtgc aactcgccgc agtgattggt ctttttcagg cacttctgct
     8161 acagacatga cagttgtcca atttttccaa tctttatttt ctaccactaa agtgacaggt
     8221 gaaccaattg ttttgccgtg acggatgcca gacgtgatcc gaacacgatc tttttcgatc
     8281 ttcatccttc ctcctctgcc gtaaccagct tgtctgcgag cgagttcgtg attgatttct
     8341 tcttctgaca gaggtaatcc tgctggtagt ccttcaataa tggctgttaa ttctggtcca
     8401 tgggattctc ccgcagtcat ataacgcatc ttacagtcct cctaagtaat ctttgaatgt
     8461 ctctgtggga acaggaacga tttttgcttg cccaatcttt tctagcaaga tgatattcaa
     8521 ttggcttcct cttgctttct tatcatgggt tatcgcgtgg aataattcat ctggatgact
     8581 tagatcgtac gtaatcggca gatggaattt ttgaagtatc ctttctaaag cagctgtcga
     8641 tccagttgga gacaagccga ttttttctgc atgagaagtg atggctacca ttccaatagc
     8701 tactccttct ccatgactga ctaccccata tcctgctgta ttttcaattg catggccaat
     8761 tgtatgacca aaatttaaaa taagtcgatt tccttggtca aagacatctt cttccactac
     8821 ttttcgtttg atttccaacg tagcagtaat gattggaaca gcatgttcca gaagatcttt
     8881 ttcgtctttc agctcgttca gctgtttcca aagcgttgca tctgctatag ctgctgattt
     8941 gatgatttca gcgattcctt ctcgtaaacg acgtaccggc aaagttttta gaacctcagg
     9001 atcaatcaat acaccagctg gctggctaaa tgttccgaca aggtttttcg ctttgtttgt
     9061 attgactgct gtcttcccgc caatactaga atctacttgt gcaagtagcg tagtcggaat
     9121 ttgaacgaaa tggatcccac gcatgaacgt cgaggccacg aatgctgcta gatcacccac
     9181 cattcctcca ccaagtgcaa gtatcccatc gctgcgggta aaatcattat ctgctaaaaa
     9241 atcgtataac tcagctgctt gttctaaaga tttactggtc tcacccgccg gtacgattga
     9301 aaggactggt tcaaaattag cttgtctcaa ttggaacatg attttttctg catatagtgg
     9361 agcaacgttt gtatcagtga tcacagctac tttttgaggt ctccaaatcg tttgaagcca
     9421 tgatccagcc tgttctagtg cgcctttttc aatatgaata tcgtattttt ggttatcaac
     9481 atgtacagta agcattcgtt tcacttcttt cttttaaaaa gctggaatta atcgagtgtc
     9541 tgaatctttt ccattgcttc tttcatgatc gcaacttctt tcatcatgcg tgagtaagtc
     9601 ttttcattca acgattgggg accgtctgac caagcatttg caggatcagg atggatctct
     9661 acgatcatgc catctgctcc gcttgccaca cccgcacgag ccattggtgg tacaagttcc
     9721 caaattcctg taccatgact tggatcaaca atcacaggga aatgagttaa ttttttcatc
     9781 aatgggacag cacttaaatc aaacgtatta cgtgtcgctg tttcgtaagt ccgaatccca
     9841 cgttcgataa aaatgacagg agatttgtct tcgactgcaa tgtattctgc agcattaagc
     9901 cattcattga tcgtaccgga aattccacgt ttcaatccaa caggtttacc tgttttaccg
     9961 acagcagata gcagtttaaa attttgcata ttacgtgcgc caatctgtag gatatcgctg
    10021 tactcagcca ccatatcgat atgcccttca tccatcactt cagtaatcac tttcattcca
    10081 aattcatcag ccgcttgacg gatgtatttc aatccttctt cttctaaacc ttggaaagca
    10141 tatggagaag tacgtggttt gaaggcacca cctcgcagaa tttttgcgcc cccggctttg
    10201 gccattcgcg cacattctct gatttggtct aatccttcga tagaacaagg accagccatc
    10261 gtcacgaaac tgccgtcacc aatttttact ccgtctacat ccacgactgt attgccagga
    10321 tggaattctc gagaagtcaa tttgtatgtg tttaaaatac gcacagcatt ttctactcct
    10381 tcatagcgtg taaatgctcc ttcttgtaaa cttcgcgtat caccttttag tccaatcact
    10441 actcgttctg ttccttgatc gattgagact ttgaatcctt ctttttcgat atgatcgacg
    10501 acttttttta tttgttcttc cgttgcttct tttttcataa ttactatcat tgtttttccc
    10561 gctttctttt gtttacttat ctatcttggc tgattttctc tactttttca aggtggtttt
    10621 acattaattc ctactaaatg accgtgtcct gttgttctca ttttcgctcc ttctttccta
    10681 cttatgaccc agataatcaa caaaaaaaga tgtccctgta ggaaattgcc tctacagtga
    10741 acatcttcaa cgagccttaa aaagcgctgc aaaaatataa aatagccact atagatgaat
    10801 ttctctacgt ggctgtaagt cgtgtttaaa aatctttagc catcatagat acaaacctgg
    10861 tttgtttgta cccacgaagt catgaataca aacctatcta aaatagctaa agtaatacgt
    10921 attcagtttt gtaagttttc tagatttcat aaaaaatcgc tccaaactga tgtaagaatt
    10981 gtacctagta tagacataaa aaaatcgact gtcaatcatt tttatgaaac tttttttaat
    11041 tttctgatag ttaactttgt ttttcagaaa aataacaatt ggttttattg aagaaaatag
    11101 tcatgaacaa aagtatctga gaactttttt actctcttgt tcatgacata tagaataaag
    11161 cagctttgtc ttgtaaactc cgtttttcaa ataataatct aaagattgct actgaataat
    11221 aaagccgatt tcatggtcct cttcgctgct gattcggtaa ggtgactcaa catccgctcc
    11281 ccagctattg atacccccga ctcctcttac ttttgcaaaa atcgtaagaa ccgttcgtct
    11341 ttctggcggt agttcttcta tatgtgttgc ctgttccagt tcttctgctt tgaatggtaa
    11401 agcggaaaaa gcaaatggcg tatcctgctg ttcaaatcgc aacgaaaaat cttcttgatc
    11461 tttatccgta ttatccaacg tttgatttct tgttagttct acccatttcg tttccatatg
    11521 catgccgcat tcttggggaa caaggtatgg ggaaacgggg agtcctgcca ctttataaat
    11581 accttcgaca ccaccagcca tccgatccgg atatgtttcc cctgataggc cttcatactc
    11641 aaaaaatttt gctttcgttg gcataatgaa ccttaaaccc aatgcgggta attccggtaa
    11701 tcctttttgt ccataataat gcatattgac aagcatttta ccctctccag cgatttggta
    11761 ggaaattgtc acttgggttt ttggtactgt gttgatttcc agtgtaaaaa tgatttcaac
    11821 cgtttcagcg tattcattac ttgaatattg attatttact ggagcaatcg gcaaatcgat
    11881 ctttttattg tccaccagta cttctatttc tttgactttt ggatacaatc cggctcctaa
    11941 ccacataccg gatttaaatc caaatccgct acctctgtca ttatcggtcg ttgctcgcca
    12001 aaaaactgga agtgtttccc ggtatagcca ttcttttccg tttttattga gcgattccag
    12061 tccgcctctt gtataagaaa aaatataatg cgtattcccc gatttgacac ctaatgtaca
    12121 gtcgccgaag acgattgcaa ctttttccgt atccatatga cttttattta ctgtattttt
    12181 cataataata tcttacctcc tgcatggcgg gtttttcttg tccatctgca aaaacgatcc
    12241 cattccctga gaattcatag tcacttggtt tatcgtcaaa gtcaccgcca tagcgcatca
    12301 cttctctgcc tgtgattgga tcagtcactt ggatcgcctg atctttaaaa tcccatatat
    12361 agcctccttg gtacatttca taacgatcaa gcaacgtcat gtaagaatcc attccaccta
    12421 acgaattccc catgtcatgc atatattcac ataagatgaa cggtttttcc gctttatttt
    12481 caaggtagtc aatgatctct tctggtggcg catacatgca gctttttaca tctgaaatcg
    12541 aatcttcgaa tgctggattt ggaaaattcc cttcataatg gacaagtcga tcggggtcta
    12601 cttttttgaa gtaatcgttc atttgtcgaa tgttttcttc cgcataagat tcatttccaa
    12661 gagaccaaaa aagaatactt ggatggtttt ttaatgtttc gaaattcgtt tttgctcgat
    12721 caagaacagc cgcctgccac tgaggtactg cacctggtac gttgtaagaa ggctcaaatg
    12781 cgcccatttt ttgccatgag ccatgggatt cgaggttcgt ttccgccatc acatggattc
    12841 ctgcttggtc gcataaataa taccaagtga tctggttggg gtaatgagat gtccgtacgc
    12901 cgttgatctt tgcatttttt atgatagcca aatctttttc catatcttct atagtgatgg
    12961 cgcgtccttt tttcggatgc cactcatgtc gatttacccc gttgataatc atccgttttc
    13021 cattgaagta gatgatttta tctttgattt cgattttacg aaaaccgaag gaatagtcaa
    13081 tatactccgt tactcttttt tcttcgtcta tcgtctccaa ttcaagctta tataaattgg
    13141 gctgaaaatg cccccacagt gccacatttt caaatccatc gatgcgaatc gtcatttgct
    13201 cttttaacgg atattgctgt tgatagattt ccttcccatc aggatctagt atcgctacat
    13261 tcagctgact gtttttggct acttgctcaa aagacaaatc tacttcaagt ttgccatttt
    13321 gacatttgtc atctaagcga ggtttgatcc aaagatcttc taaatggttt tgtcctcgag
    13381 caactaagaa gacatctctg aagatcccaa aaaatcggaa aaagtcctga tcttccaaga
    13441 atgcagctgt acttcttttg taaacctcca cagctagaat attttcttct tccaaataag
    13501 gtgttaaatc aaattcagac ggagtgaacg aatcttcggc atacccgata aaatgaccat
    13561 tcaaccaaat aaacattgct tgttctacac cagcaaaatg aatcgagatt tgttttccct
    13621 ttagaccttc ttctaatcga aaagtcgtca aatacgaacc aaccggattg tctttagcag
    13681 ctgaaaagat cccttccgcc tctttctcag ggcttgtcgt gaaaggggga cggcgaaata
    13741 catgtccctc ccacggatac atcgtattga tgtaatggat cttgtcataa tttgctaatt
    13801 caatatgact aggaacagtg atttcatcaa aagaacaggc atcaaaatct tttttataaa
    13861 atgtttttgg tcgtaccgaa ggatttggcg aataacaaaa acgccatgat ccatttaaag
    13921 actgtttaag ggaggatgtg gtttctactt cttcccttgt tgcataacaa acatgatcgc
    13981 tatgtgcatt tgattggttc actctaaaaa cttgtggatc atctaaccat tttatatttg
    14041 ctttcatact tttttccttc tctctcataa ctttttgaaa tgaagcagtt ctgtttggaa
    14101 atcaccttga aaatcgggga agtaaagtcc aactgtcatc aattcggccc ccgaaaatat
    14161 ccgcttcgag gtctgttcct gataaagtgc ctcatcatct aaccccatca gatatacttc
    14221 atggaacgct ggttgagctg aagctagtat cctccctaaa aacacaatag cttcatcttg
    14281 tttaggagac acaaacatcc atgcggcaat attttcttca aaaggactcg ccaaacgata
    14341 ataatggcca tactggatca ccggacgaat cgtttgatag gatataattt ggtcttttac
    14401 ttgcttttct tcttcaggag acagctttgt caaatccagt tcataaccaa aaacagcgct
    14461 catagctgtt tctcctcttg ttttcaacga agtagatctg tcggtctgat gatttggtac
    14521 agctgataca tgagctgtga tggacgaaat cggataagca aggcttgttc catattggat
    14581 tttcatacgc tccactgcat ccgtgttatc acttgtccat gactgcggca tataataaat
    14641 aaacccggca tcaaaccgtc cacctccacc agaacagcct tcccataaga tttccggata
    14701 atcagttgtc aaatgttcaa gtagttcata aagcccgagc atataacgat gcgctacttc
    14761 tccttgtctc tgtgggtcaa gggtaatcga atagacatct gaaagcgaac ggttcatatc
    14821 ccatttgatg tagtcaagag gaatcgtatc taaaatcttt ctcatttgtt tctcaatcgt
    14881 ctgccgaaca tctaaccttg taaaatccag tacatgttgt gatctggaag cagaaggcat
    14941 tctacctggc tcctgcataa gaaaatcagg atgtgttcga tacagttcag aatcaaccga
    15001 gatcatttca ggttcaaacc ataaaccaaa tttcaatcct ttgctatgag cataatctgc
    15061 tatttcacgt aatccatttg tcaacttgcc ttcatactcg aaccagtctc ctaatgaaga
    15121 attgtccgca tctctttttc caaaccagcc atcatctaat acgaacattt cgatgcctag
    15181 ctcctttgct tcatcaatga tcgccttgat tttttcacta ttgaagtcaa agtaagtggc
    15241 ttcccagtta ttgaccagaa tcggccgttc agcaaattga tgacgacctc ttgcgattct
    15301 ttcacgtagc aactcatggt ggatctgact cattttgttc aatccctgac ttgagtaaga
    15361 aaggatcatt tcaggtgttt gaaaagactg gcctgcattc aattcccacg aaaaacgatg
    15421 gctgttgatc ccaccgacga ctctcaattg attgatctga tctttttcaa gttcgaaaga
    15481 atggttgccg gaataaacaa attgaagtcc gatcgcttct ccagtatttt ctgtcgtatg
    15541 atgatgaact aaagcaataa agttattcat atggtgactg ctcgttcctc gacggctttc
    15601 aaatactttt gttccagata aaacagattg ccgtgaaatc tgtctttcat tgacatgtgc
    15661 tcctggcaaa gcaatgactt catcaaatcg cctagtatgg gcaaagtcta gctggaaact
    15721 agccgctttt tctagtttga ttgtttctcc ggtttcattt cttatcttta cagatcgtgt
    15781 gatcactgct ctatcagtaa atatggtata gaacaaatcg aaataaatcg ctgtttctct
    15841 atccttaagt gaaatcacca acgtttgtgc ctctgacttg tccatcacat aagtttgagg
    15901 caagccttcg atctctggct tcccatctgt aatataatgg ctgtcatatc tcagatccag
    15961 taagtctgat ccattcttgc gctgaatgat cgatgcgggc gttcgaaagt ccatgctgcc
    16021 atgagaagag tattcttgcg gtagtgtatc tttcgacaga gaccggtcag gatttaaggg
    16081 aacatttcct gaaaatccac gatctcttcg gggataattt ttattgtctt tgtactgctt
    16141 gactggtttg ccaaaataaa tatgcgccaa tacattgctt tcttctatct ttatcagata
    16201 agaaagaaat gtatttcgta aatggaagac tcggctcttt tcatcaaata agatgaaatt
    16261 tttatctgtt tttctatgcg taatatccat catttcactc ccaacaaaac ggaaaccgtt
    16321 tacttttttt tataattcct gtatactgtt tactaaacaa ttttgtcaat aaaaattttt
    16381 tatttttttg aggagtgtgt aaaaatggtt ggaattagag atgtcgcacg aaaggcaaat
    16441 gtctctcctg ctacagtttc ccgtgtgttg aataacgatc agacgatcca tgtggctcag
    16501 actactcggc aacggatagt agaggcagct gctgcgttgg attatgacat cagtactcgt
    16561 aaatatatca aaaagagaat gccttcgatt ggtgtgatct ctacgatcgg caaagcgagc
    16621 gaagaacagg atatctatta caaacatttg cgagtaggga tggaagaaga agctcgacgt
    16681 ctgcatttag ggatgaatcg aatctataat ctatctgata atcctaaaca atgggaagat
    16741 ctagatcagt taggtgcggt gatcgttgtt gggactgtta cgaaagaatc gattaccgcc
    16801 ttgttaaaac aaaacatgca aatagtcgtc gtggataacc ctgacatcca gcaagaggtc
    16861 gatatggtgt atgcagatct tgaacggatg actaaaaccg tactggaatt gttcttagaa
    16921 aatggtcata aaagaatagc ctatatcggg ggatataaag tcgatatgga tgaattcggt
    16981 gggaagcaga tttctataaa tgaaaagagg atgcgtgcct atcagcattt tatgatcgat
    17041 catcacttag aaaaatatat gtcttatcat ctaggtggct ggacagaaaa acaaggtgag
    17101 gtacttgcga ctaatctatt agaaaatgaa tcccctcttc ctactgccat tcttgtcggg
    17161 agcgatccaa tggcaattgg tgtctatcgg gcattgaaac aaaaaaatat ccaaattgga
    17221 gaagagattg ttgtagcaag ctttgataat atcgagacaa tcgcaaacct ctcccctggc
    17281 ttgaccagtg ttcaaatcaa tgcgaaatca attgggcaag cagctgttcg aatggcattg
    17341 gagcgaattg acggtatacg ggacgaacca atcattttga cttatcctgc acgattgatt
    17401 gttagggaaa gttttatccc aagaacaaaa aggtattgaa agagaggttg tgaaaagccg
    17461 cttcgtttct tcatactcaa aacgaaacgg ctttttcaca acctcttact tatacttatt
    17521 cacaaaatcc aatgtctgct ggtaacaatt ttgcgattct tttagcgtgt aatcaaattg
    17581 gtattcatgg gtaatctctt tttttgtatc tgtataaaac aaggattgca cgggtacctt
    17641 taattctgtc aaccgatttt ctaatgcttg accttgctcc tggaatgagt atgcatttcc
    17701 gtcagttata tacgttggcg gaaattcctt agaaacatgg tcagccacac tagcttcttt
    17761 caattgctca ctcgttttcc aatcttttgt tccaatcaac gaccacgcaa cggttttgac
    17821 gaaaaacttc ataaatcgat catccgaatg ctgctgtgct gttagcttca aatcaacagg
    17881 tccgcaataa gaaatggttc ctttcagact atcttttgga agtagctgtt tgattttcat
    17941 ttgtttagca tacgcatcat tcgtttgtat agctgcatat tgcaatgcga tttgtgaacc
    18001 tgcactatct ccaccaaaaa ataattgttc catgtctagc aatttgtcgt ctttttcttc
    18061 agctaataaa tctttgatca gttcattcac ttgaagaact tgattagggt attctgaatc
    18121 aggcgctaat tcataattca tcgcaaccac tgcgatgttg gcgtctgaaa ctaattttgt
    18181 cgcaaattct ttgacacccg atttatctcc gccgacgaat cctccaccat gtacccaaaa
    18241 tagaacagga acaggcccct tgctgttttt tggatagtag atgtcataag tattctcttt
    18301 atacttggac tcatacgtca aatctgtttt tttcgccacg tttttttctg cttgatcgaa
    18361 cgttttttta tcagtgattt gaacagtatt tgaaaacata tggttgatca agaatgctcc
    18421 aggtctgggg gaaagctgga aggcaagaaa gattgcaaac gcgatcccaa gaatgattcc
    18481 gaagaaccat ccgataaatt taagaatttt ctttttcata aggctccctc agtagttagt
    18541 attaagcatt ctgattatac catagtgtta tttcctatca agctctccta gatgatttaa
    18601 tgattttccc caaacttctt ctgcaatgct tttgacaaaa gaaatttttt ccattgttct
    18661 tcaaacaaaa cattttcttc ttctgttgaa gcaaatccac attgaggact taagcacaaa
    18721 cgatccaaag gcagatatcg tgtcgcttcg tagatccggt caatcacttg ctggtgctct
    18781 tccatttcgc catttttcgt tacagtcaaa atctaagaca actaatttat cttcagagac
    18841 tttctctaaa agaacaaaac tcccagcacg ttcactatcg tattctaaat aataggcacg
    18901 gacattttct tgagtaaaat aatgggtctg ctacgtcgtc atcccccctg atgccgccaa
    18961 aatcgaataa taatttccgc gtcaaacatg tatatttagt gttgaatcat ttgagaatat
    19021 gaaaataaaa atctttttga tcaatcagtt aatcaaattg aaataacgaa aaatctgaga
    19081 cagaatgacg ttcattctga cccagatttg attttgcaca actcaacagt ccttattggc
    19141 aaatcgccaa aataatgtag actaactaaa aagactaaga aacaataaca aaagttaaca
    19201 cttcttagtc tttctttagc acgtctattt attaaagatt ttagggcctt ttctcatgtt
    19261 tttacgatca ttcttaggtg tttccatttg tttggatcgg cctccacctt gtttcttttt
    19321 gatcaattct ttcatttttt ctttttggtc catttttatt ctcctttaac gaatgaagcg
    19381 actaattcga tatgatgggt ttgcgggaaa agatctacag gctgaacttt cttcacggca
    19441 taacctgctt ctgcaaataa cttagcatct cttgcaaaag ttgccggatt acatgagata
    19501 tagacgattc gttctggtga catttcgatt gctgattcaa taaaatgatg atctaatcct
    19561 tttcgtggag ggtcaactac gatcacagat ggtttgatcc ctttttcttg ccattttttc
    19621 ataacttttt ctgcttttcc gacttcataa tgaacatttt cgattttatt atttaaagca
    19681 ttgaactgtg catcttcaat tgcttctgga ataacttcca tcccatacac cttatccact
    19741 ctgtctgcta aagacaagcc aatcgtacct attcctgaat aagcgtcgat cacaatgtct
    19801 tttttatcta actcggcaaa ctcgatggct gtttggtaca gatactctgc ttgttgagta
    19861 tttacttgat aaaatgactt tgctgagatt cgataggttt ttcctaatag ctgatcttcg
    19921 atatagtctc tgccatataa aactttttct ttgtctccta aaatcacatt tgttttttct
    19981 tcattgatat tttggatgac cgaaaccact tctggcaatt cttcatgaat agcttcagca
    20041 atttccttgg atttaaagaa tttttcttta cgagtaacta aaacgaccat catttcatgg
    20101 gaataatgac cacgacggat aatgatgtga cgaagctgtc cttcattttt ttcttcatta
    20161 tatcctcgta cttggaaccg ttgcaagata tctctgacta ctttgattgc ttgatcgatg
    20221 acaggatctt ggatataaaa atcttcgata gggactagat catggctatt ctttttgtaa
    20281 aaaccggtgg ctaactgtcc atcgatacgg cgaacaggga tctgtgcttt attacggtag
    20341 ccgaatggtt ctgccattcc gaccgttgga agtacaggaa cttctggcat cttagcaatc
    20401 ttcgccatta catgctctac ttgtttttgt ttgaagacaa gctgttgttc atacttcaaa
    20461 tgggctaaag gtgcgatacc tatgcgaagt aatgcattgt tttctacagg ctgacgatca
    20521 ggtgattgtg taataaatgt ttcgactttt ccatatccaa acttattgcc tgcttttact
    20581 actagtattt ctacttcttc tccagggagt gcattttcga taaataatgg ataaccatcg
    20641 atttttgcta cccccattcc ttcataactc aagtcgacga tttcgactgt atatcgttcg
    20701 tttttcttta ctatttgctg ttctgtcata ttttgctcct ttaagcctat ttttcaatcc
    20761 tactgaactc tactataaat cagctaatta cacaactaaa accggcactg accttactac
    20821 gttcagcacc ggcttttgat taattctttt gattaggtgt ttcgtctgct atttttccgt
    20881 caccgtcgat atcttcatcc gttaaacgtt cgacttcttt tacgaattct ttgctgacaa
    20941 cctctaattc ttcttcatct gtacctgtga ttgcttcatc aggaatctga tcggtattgg
    21001 caaagaactc aatgtgttga tgaagatttt ggaaatgcat cggtgcttcc ccgccgtatt
    21061 caccatctaa gttgatcatt actggtcgat tgatatcatc ttctgtttca acgaacaaac
    21121 tgcttgtttt ggtatagatt attcttggat catcgacatg tcgaccgcca ttcagcatga
    21181 gtgctgcaat atgcaagatc tcaaagatat ttgctgtctt cacaatgatt aaagaaaact
    21241 tcccatcatc caatttggca tctggcgcga tctgttcgaa tcctccaaca gagttcgtca
    21301 gccctaggaa aaacatcgaa gcatttccga tatattcccc ttcatcatac ttcaagcgca
    21361 ttttgattgg ctttactcga gggagcatct ctgctccttt cgcaagataa gcaagataac
    21421 caaaaatact ctttagttct gatggaactt cataagtcaa ttctgtcaaa tagccacctg
    21481 cagcgatatt gatgaagtaa ctgttatcag aaaggccgat gtccattttt acggtttggt
    21541 gtttttttat cacttctgct gctgctttaa tattatctct aggaattttt aatgctcgag
    21601 catagtcgtt cgttgtacca gctgggatga tggccatttt aggacggtgt tcaagcggag
    21661 cgattccatt aaccacttcg ttgattgtgc catcgccacc agctgccact actagatcaa
    21721 aacctagttc tgcgactcta catgcttcat tcttggctga atctggttct ggtgtagttg
    21781 cataggcgct ggcttcaaat cctgcttctt ctaatgcctg taggatatcc gccaaatttt
    21841 ttttcaataa ttcttttccc gaggtggggt tataaattac gcgtgctttt ttcattttca
    21901 gcctctatcg tttcgctaat tcatctttaa gtagcttatt cacgacacca ggatttgctt
    21961 gtcctttagt tgctttcatg atttgaccga ctaggaagcc aaccgcacga tcttttccat
    22021 ttttgaaatc atcgacagat tgttggttgt tatccaaaat ttcattaatg attggcagta
    22081 gtttgttcgg atcagataat tgcacccaac catttttttc aactacttct tgggcttctc
    22141 cgccatttgt gatcaattca cggaagactt ttttggcgat ttttgagctg atcgttccat
    22201 cggcgatcaa acgaatcatt cctgctaagt tctcaggtgt caattttgtc tcagctaatt
    22261 ccagtttctc actgttcaag taagcagaaa cttcacccat caaccagtta gatgcttgct
    22321 tggcatctgc accattttcc aaaacagctt caaaaaaatc agacatttct tttgtaagtg
    22381 tcaataccat tgcgtcatac tctggaagtc caaactcacg gatatagcgt tcgcgacgag
    22441 aagctggcat ctcaggcaaa ctagctttta ctttttgaat ccattcgtca tcgatcacga
    22501 atttcgggat atcaggctct gggaagtaac gataatcact agacccttct ttgacacgca
    22561 tcaaaactgt tttattcgtt gtttcgtcaa aacggcgtgt ttcttgttgg atttctcctc
    22621 ctgaaagaag aacttttgct tgacgttttt cttcaaaagc taaacctttt ttcacgaaag
    22681 ataaagagtt caagtttttc aattctgctt tcgtaccgaa ctcttcttgt ccataagggc
    22741 gaagagaaat attggcatca cagcgcatag agccttcttc cattttcaca tcgctgactt
    22801 ctgtaaattg gataattgat cgcaatgctt ctagataagc gtatgcttct tctggtgaac
    22861 gcatatcagc ttcagaaacg atttcgatca aaggcgtgcc ttgtcggttc aaatcaacgt
    22921 aagaataacc gccaatacca tgcatgtttt ttccagcatc ttcttctaaa tggacacgtt
    22981 cgatccggat ttttttcttt ttaccttcta cttcgatttc gatccatccg tcatgaccga
    23041 ttggttgatc aaattgggaa atttgatatg cttttggatt atctgggtaa aagtaatttt
    23101 tccggtcaaa atgagtatct ttagagattt cacagtttaa tgccaaagct gctttcatcc
    23161 cgaattccag cgcagcttta ttcattactg gcagcacgcc tggataaccc cagtcgatca
    23221 cgtttgtatt gctgtttggt tctgcaccaa aatgagctgg cgctggagag aaaatttttg
    23281 agttggtttt taactcgacg tggacttcta gtccaatgac tgtttcaaaa ttcattcgtc
    23341 tttccctcct aaaatagctg gttgttgttt atggaattct gttgcttgtt caaacgcata
    23401 tgccgcttga tacatcgttt tttcatcaaa ataattaccg atgatctgca atccaactgg
    23461 taatccttct gataaacctg ccggtacaga catacctgga agtccagcca agttgacagg
    23521 gatcgttaag atgtcactca tgtacattgt gattggatcg ttaatgttct caccgattcc
    23581 gaatgcaact gttggtgaag atggcccgat gatcaagtca taatctgcaa agactttttc
    23641 aaaatctcgt ttgatcaatg tacggacttg tcctgctttt ttgaagtaag cgtcataata
    23701 acccgcgctt aaggagaatg tacctaacat gatacggcgt tttacttctt caccgaatcc
    23761 ttctgaacgt gagttgacat atacatcatc taatgatttc acattttcag agcgataacc
    23821 gtagcggata ccatcgaatc gttgcaaatt ggaacttgct tctgatgagg caatgatata
    23881 ataaacagcc acaccgtatt ttgaatgagg caagctgact tcttccacaa cagcacctaa
    23941 tgaacggaat gtttctgctg ctttcaatac agcttctttt acgccagggg ccacaccttc
    24001 gcctaagtat tctttaggta aagcaatctt cattcctttg atgtcgcctg tcagtccctc
    24061 tgcaaaatca ggaactgaaa cgcctgaaga agtaccgtct ttttcgtcat aaccgctgat
    24121 agctgtcaat gctaatgcat tatctttcac cgtacgggtc attggtccga tttggtcaag
    24181 agatgaagca aaggcaatca aaccaaaacg tgagacacgg ccataagtag gtttcatccc
    24241 tacgatgccg ttaaaagctg ctggttggcg gatacttccc ccagtatcac tacctaaaga
    24301 aactggaatt tgtccagctg caactgctgc tgcagaacca ccagaagagc caccaggtac
    24361 ttttgttggg tcccaagcat tttttgtttt cttgaaataa gaagtttctg tacttccacc
    24421 catagcaaat tcatccatgt ttagcttacc aacagggatc atatctgctt gatagatttt
    24481 atccatgacc gttgcatcat aaattggttc aaaattgtaa aggatcttag atgcagcggt
    24541 tgtcaagata tcttttgtta cgatattatc cttgatacca attggaatac cagcaaggac
    24601 gttgctttca tcaatccctt tttcatctaa agcttttgcc tgttccaatg ctttttcttc
    24661 gttcaatgta atgaatgcct cgacctcagg ctctgtttct ttgattcgtt caaatgttgt
    24721 ttttgtcaaa tcttgtacag tgatttcttt cgatacaagc atatgatgca gttcttctag
    24781 agaacgattg tgtaattctg tcattatgcg ccagcctccc cattatcgat gattgcgggt
    24841 actttgataa agccgtcttc tgtttccggc acatttttca ataattcatc gcggttccat
    24901 ccagcttgcg cccgatcttg tcgcatcacg tttactgttt caaccacatt cgacgtaaat
    24961 ggaacacctt ccgtatctac ttcttccagc atttcaacca tatcgatgat tttacctaat
    25021 tggtcggtaa aacttgcaag ttcttcatct gcgaacgcaa gttttgctaa tttggcaacg
    25081 tgtttcactt gttcttcact aatcgccata ctaccccttc tttctaaacg agttaaaaac
    25141 tttgctctct attttaacac aagagtgccg tgtctgaaat tgtttattga aatttgtctg
    25201 aaaaaactca tttttcattc ttctactgag cgacttttag ccaatgcatc tgccatttga
    25261 tcttctgtcc aaacttcgat tcctaattct tgtgctttgg tcagcttgct gccagcatct
    25321 tctcctgcta ccacgatatc cgtttttttc gatacgctac cagtcacttt cccgccaaga
    25381 ttttcgatcg tctcttttgc ttcttcacga gtaaatcgtg ttagtttacc agtaaggact
    25441 actgtttttt ctttaaaagg agactcgact tcttgcaatt gggcatttcg aagccctttg
    25501 tattcgaaat tgacgcctgc ttgttttaat tcattcatca attcatggac ttcttcgtta
    25561 ctgaaataag tgactacact gtcggcaatg atatcaccga tcgtatcaag cgcaataatc
    25621 gactcatagt cacttttact caatgtttct agatcaccga aatgttctgc taaaattttt
    25681 gctgctttcg ctccgacatg tcggattcct aacccgaaaa tcaaccgctc gaccgaatta
    25741 tctttgctgt tgtcgattgc tgtcaaaata ttatttgctg atttttcttt tattttgtcc
    25801 aacgtcaata actcttcttc tgtcaatttg taaagatcag caacatctgc tactagtttt
    25861 ttatcataca tctgttctag tacgcgcggc cccaacccat cgatattcat cgcatttctt
    25921 gaaacaaagt ggttcaaacc ttctttcatt tgagcagggc atttaggatt gatgcaccgt
    25981 aaggctactt cttcatccaa atggacaagt tcacttccac aaactggaca atgtgtaggc
    26041 aattggtatt cttcgctgtc tttaggtcgt ttatctaaca cgacttgcga aacttctggg
    26101 atgatgtctc ccgctttata aatcagaact gtatctttca agcggatatc cttcaactta
    26161 atataatcac cgttatgcag gctggcacgg cttactgtcg ttcctgctac tcggactggt
    26221 gtcatgatag ctgttggcgt tactacccct gttcgaccga ctgtccattc gatgttttcg
    26281 attagcgttt caacttcttc tggcggaaac ttgtaagctg ctgcccatct cggtgctttg
    26341 atagtaaaac caagttgatc ttgtagcgag aattcattca ctttgatgac gattccatcg
    26401 atttcatagg gcaaatccac acgtttgtca tgatattctt caatgtatga ccacacttca
    26461 tcaatcgaat gacatagacg tttttcccga ttcgtgtgga atccaatttt ttctagctct
    26521 tctagcgcat catactgggt ttttgcttgc ataggaccga aatcagctac tgtgtataaa
    26581 aaagtgtcca gatttctttt cgctgtgatt ttagaatcta actgacgcaa agaaccagct
    26641 gcggcgttcc gaggattcgc aaagatatct tttccctctg cttctctgtc ttggttcaat
    26701 tggacaaatg accgttttgg catgaaacat tcgcctctta cttcgatgtt cattggttct
    26761 tttaatttga ttgggaccga ccggacagtt tttaggtttt cagtgatgtt ttctcctaca
    26821 gttccatccc cgcgagtcgc acctctcacg aaatttccat cttcataacg caaagaaacg
    26881 gaaagtccat ctatttttag ttcacagcaa tagtcaacta cacgtcccac tgctttttgt
    26941 acacgttgat caaaagctat cagctcttct ttgctgaaaa cgtcgttcaa actgtaaagc
    27001 ggaatatcat gagtgacttt ttcaaaacct tctaatactt ttccgcctac tcgttgagtg
    27061 ggagaatcag acgtgatcaa atcaggatat tgttcctcga ttgctactaa ttctgcgtat
    27121 tctttatcat aaacatagtc ttccactgtt ggtttatctt ctacgtagta ttcgcgagac
    27181 cattggttca gtcttgtacg aagttcttct gctcgtttag cagcttcgtc aatcgtcatt
    27241 tcatgttcca tcatttaccc tccactacta agctttttca attggcgcaa aggcagccaa
    27301 aagacgtttt actccttgac ttgggaaagc cacatctagt tctagatcct tcgacgtccc
    27361 gcttactcgg acgactgttc ctagacccca ttttttgtgt ttgactttat ctccaggttt
    27421 ccagctgtta ttttcccctc cagtagcact tttagaggga acaaccgctg tctctggctg
    27481 tttatagcta tatgctgttt ttttagcgaa tacaggcgtt tttttaggcg taggacgcat
    27541 gccttcgatt tccagtaact cctgatcgat ttcttctaca aaacgagaag gtcggttata
    27601 ttgcgtccgt ccatataatg ttctggagaa agcatttgtt aaatacaacg cttcttctgc
    27661 tcgcgtgatc cccacatatg cgagacggcg ttcttcctcc agttcgcttt cttccatcaa
    27721 tgctcgagat aaaggaaaaa ccccctcttc tagaccaatc aggaatacaa ctggaaattc
    27781 taatcctttg gctgcatgca aagtcatcaa tgtcacttgg gaagcatctt cttctaaatt
    27841 gtcaatgtcg gaaacaagtg ccagatcatt taagaagacc gttagttttt cttctggtgc
    27901 atcagcgtct tcttcatttt gctgttcgaa ttgtttgtcg aattcttgtg tgaccgttaa
    27961 aaattcctcc aagttttcga tgcgtgcttg tgcttctaat gtattttgga tttttaagtc
    28021 ttctagatat ccgctacgat ccaaaacctc tttcgtcaat tctgtcactg tcaagtatgg
    28081 gatcatctga gtgacttctt ggatcatctc tccaaatgca cctaattgct gtcctgcttt
    28141 tccaccgata tttgccagat ccacattttg cgctgcttca agcagtggcc attcatgaag
    28201 agaagcaaaa ctgcgtagtt tttcgataga tcctggtccg atgcctcgtt tgggcgaatt
    28261 aacgatacgc tcaaaactga ttgaatcttg aggatttacc agcacattca aatacgctaa
    28321 aatatctttg atttctttac gatcgtagaa cttgtgccct ccaaccattt tataaggaat
    28381 atttgctttc aacagagttt cttccattac acgagattgt gcgttcgtcc ggtacaagat
    28441 ggcaaagtcg ccgtaattcc gatgattgct tcgaatctct tcttgcatcc ggtctacgat
    28501 aaaacgggtt tcgtctcgtt cattatctgc acggtagtaa gtgatcttgt ttccttcttt
    28561 gttttctgtc cacaagtttt ttggttttcg attgctattg ttttcaatga cttggtttgc
    28621 tgcgctaagg atgtttttcg tggagcgata gttttgttct agcaaaatta ctgcagcatc
    28681 tggataatct ttttcaaaat ccaagatgtt ctgcatatct gcaccgcgcc agccgtaaat
    28741 actttgatct gcatctccca cgacgcacag gttcctaaat ctacctgcca ataaattgac
    28801 tagcgtatac tgtgcgtgat ttgtatcttg gtactcatct acatgaatat aatggaattt
    28861 gttttgataa tacgtgagtg aatcaggatg ttcttcaaat aatcgaatcg tattcatgat
    28921 caggtcgtca aagtccatac attgattata ttgaagctct ttttggtaag cagcataaca
    28981 ttttgccgca atctcttcgt aataactgcc ttgcattttt gcaaaatcct gaggggtctg
    29041 caggctgttt tttgcttgag agattgttcc taatatactt cgaggatcat attttttcgg
    29101 atcaatgttc agttctttta gtatccgttt catcaaggtc agctgttcag aagaatcgat
    29161 gattgtaaag ttccggttat acccgataaa atcaacatct cttcttaaaa tacgcacaca
    29221 catcgagtga aaagtcgata cccagacatc ttcgcctcca gatgcgagaa tcgcattgac
    29281 acgttctttc atttcttttg cagccttatt ggtaaaagta atcgctagga tgttccaagg
    29341 attgacttct ttttcctcaa tcaaataggc aatgcggtgt gtcagcactc tcgtctttcc
    29401 acttcctgca cctgccatta gcagtaatgg tccgtcagtg tgaagaacag cttctttctg
    29461 acgggggttc atcccgttta ataattcagc tttggatgac attaacaaca tcctttcttt
    29521 tatcaatctt gttaattata gcattttctt ggctttcatt aaactagcta gttcaaaatc
    29581 atttgtttct ttttatggat ttttccttgt caattcgttg atttcgcgct aaattaaaag
    29641 aaagcgaggc gtttgaatgg aaaaaaaagg aaaaatcaag aaattagata agactcagat
    29701 atattttatt ctaaaaggaa tatttgttgg actgctgaca ggaatcgtcg ttagcctgtt
    29761 tcgattatct atcgaaaagc taagcgattt agttcgaagt atctatgaaa tgagtcggga
    29821 acagccgatt tacttaattg gcctagctat ttgctgcatc cttgcagcat ttttcgtggg
    29881 ttatctggtc aaaaatgaac cggatatcaa gggaagcggg attccacaag tagtgggaca
    29941 gcttcgcggg gaattatcaa tgaactggtt ctctgtttta tggaaaaagt tcattggcgg
    30001 tgtactttca gttggtgcgg gcctttttct aggtagagaa ggaccttcta tacagcttgg
    30061 cgcatccatt ggacaaggag ctggacaatt gtttcggagt ccatcttcag aagaaaagat
    30121 tttaatttct agcggtgcaa gtagcggact tgcagcagca ttcaatgctc ctatcgcagg
    30181 attactcttt gttttagaag aaatccatca ctccttttct ccacttgttt ggctgacatc
    30241 atttgcttca gcaatcactg ctaacttcgt ctctctttac tttttcggct tgagacctgt
    30301 tttatatcta ggtgaccttc cttctttgcc gttgaaatat tatggttcct tagtgatctt
    30361 aggagtactt ctaggcatct taggttttat ttatcagaat gtcttgctgg ctttgccaaa
    30421 attttacaac cgattgcctt taccagctta ttttcacggg ttcgttcctt tcttgctgat
    30481 tttgccaatt ggttatttat ggcctagtac tctaggcgga ggcaatcaaa tcgttttagc
    30541 ttttggacat gcttccttgc caatcattat gattatcggt ttgtttgttc ttcgattcgt
    30601 tttttccatg atttcttacg gtgggggtct tccagggggg attttccttc cgatattgac
    30661 attgggggct ttaatcggta gcttttatgg aaacattatg gttgatttcg ggatggatcc
    30721 aatctacatc aaggattttg tcgttattgc catggctggt tatttcacag cgattggaaa
    30781 agcaccgctg acagcaatta ttttagtgac agaaatggtt ggctctctta atcatctgat
    30841 gcctttagga ttggctgctc ttgttgctta tatcgtcaat gaccttctcg gcggtaatcc
    30901 aatttacgaa tcattattgg aacgtctact tggaaatact cagaccgcct cactaaaagg
    30961 tgcaaggaca acttttgatt ttccagtaac ggcagagagt tctttagacg gattaatggt
    31021 acgagacttc aattggccta aaaatatgct gctaatctct atacgcagag gaaatcagga
    31081 aatcttgact cacggtgata cgatcatgaa tgtaggagat attttggtta tcttgactga
    31141 tgaagcaaac ttgccaagaa tcaagcagga aatcgaggct aaatcttcta tcacaaattt
    31201 gaagcaatca ttttaacgaa catggaaaaa ctattttaca acaactattc atctacacta
    31261 cttgattcta tatgattcta taaaaaaaga agaggctggg aaaacccagc ctcttctttt
    31321 ttatttctat gcttctgcta ctgcaggagc ttttctcaat aaaccataaa tcacaccaga
    31381 tacgactgct ccgatagcaa taaacaccaa atacatgacc gggtgactca gtaagaatac
    31441 aacgaaaatc ccgccgtgag gagccagtaa tttgattccg aaagctccga ctaatccgcc
    31501 agttaaagca gaaccaataa taaaacttgg aatggcacga atcgggtcag ctgctgcaaa
    31561 tggaatcgat ccttccgtga caaacgatag tcccatcacg atgttcgtca aaccagcatc
    31621 ttgatctgtt ttgctgaatt tattcttaaa caaacgtgta gcaacgaaaa ttgccaatgg
    31681 aggtaccatt cctccagcca taacagaagc catcacgaca cttccgccag ttgcaacagt
    31741 cgtagctaaa gttgctgtac caaacacata agcggctttg ttgattggac cgcctaaatc
    31801 tgccgccatc attccagcta ataatgcacc aagtaaagca gcattcgaac cactcatact
    31861 tgtcaagaaa ccgttcaatg catcattgat tgctttcata gggacattga ccagcaacat
    31921 caagaaacca gtaatcagta agccaaacac tggataaaag aggatcgttt taattccatc
    31981 caatgatttt ggtaagttct tgaataattt acgtaaaaat acgatgacat aaccagctaa
    32041 gaatccacca atcagtgcac ctaagaatcc tgcaccgcct gtattagcta atgcaccagc
    32101 agcaaatcca acgatcaaac cagggcggtc accgatactt gaagcaataa atcctgctaa
    32161 taccggcagc atgaaaccaa atgcagcttg tccgatttgg ttgaaccagc tagcagcttg
    32221 attgtaattc cctagatttg ataattgatc atgtggcacg ccaataaatt ggtcgatcat
    32281 gaaagaaagc gcaatagcga ttcctccacc aataacgaaa ggtaacatgt gtgatacgcc
    32341 gttcatcaaa tctttgtaaa ttctttgtcc gatagtacca tccgcatttc cttcttctga
    32401 actgctttct tttccatcac catggaatac tggtgcagta ccactaaggg ctagattgat
    32461 caactcttct ggtttacgga taccatcact gacaggacga ttgatcagtt cttttccgtc
    32521 aaagcgattc atctctactt ttttgtctgc tgcaacgatt acaccttctg cacgggcgat
    32581 gtcttcagca gtcaatcggt ttttgattcc ttctgaaccg ttcgtttcga ctttgatctc
    32641 cacacccatt tctttcgctt ttttcttcaa agcatcttct gccatgtaag tgtgagcgat
    32701 ccctgttgga caagctgtaa cggcaacaac gaattttctt tctggatgag cagaagcttc
    32761 tgcagcttgt gtttcttgtt ctgctttttc ttctgcttct ttttgctctt cagctgtttg
    32821 gaacaagtct tggacttctt ctggtgtatt tgcttctttt aattttccta cgaaatctgc
    32881 atcaatcagc aatcgagata gtgctgctaa tgcttgcaaa tgtgtgtcgt ttgcgccttc
    32941 tggagctgcg atcatgaaaa acagataagt tggctgtccg tctaaggctt cataatctac
    33001 tcctttttgg ctttttgcga ataaaactgt tgcttcttta actgcactgt ttttcgcgtg
    33061 aggcatggcg attccatcac caagacctgt agaagtttgt gcttcgcggg ctagaattcc
    33121 ttctttatat gtttcgatat cggaaatccg gccggcatca aacatttttt ggaccatttc
    33181 atcgattgcg ccttttttat cagtcgcttg caaatccatg atcatcgctt ctttgaccat
    33241 taaatccttg atattcatga ttatcctcct tgaaactaat caatttttgt gatttcaact
    33301 tctggcagca actcatcaat caattcgcga gctgccaagt catcagaaaa agctgttgcg
    33361 cttccgcaag caactcccca tttaaaggct tcgattggat ctttcgtacg gctgtaagcc
    33421 ccaataaagc cagcaatcat tgaatcccct gcacctactg aatttttcaa tgggcgaact
    33481 aatacattcg ttttataagt tccttgttcc gtgaagagca aagcaccgtc tccagccatt
    33541 gagatcagca cattctgtgc cccttcagct agtaattttt tcccatacgg aatgatttct
    33601 tctacagatt ggaaggttgt gttgtaaagc tcagctaatt cgtgattgtt tggtttgatc
    33661 aacaacggtt tcttaacaag tgcatttttt aggtcatcac ctgttgtatc aatcacgaaa
    33721 tctgcacctt tttctcgaat gatatcaatc agttcttgat aaaatccttt tcgcaggcta
    33781 gctggcgcgc ttcctgacaa tacgacgata tctccttgtc ctactgttcc taatgcttgc
    33841 ttcaactcat cgatttcttc atctgaaata gatgggccta agccattgat ctcagtttca
    33901 gtgtctgatt ttagtttgat attgattctt gtatcttctt ttacggttgt gaacaaagac
    33961 tggatttgtt ctttttcaag ccacttcgaa ataaattcgc cagtgaaccc tcctaaaaac
    34021 cctagtgctg tagattgaga atcgatccgt ttcaaaatac gggaaacatt gatccctttt
    34081 cctccaggta acttgaagtc ttccttcatt cggttcaaat cgcctagttt taacccatct
    34141 acgcgtacga tataatcaat tgatggatta agtgttactg tgtaaatcat tgtattgcct
    34201 ccttaattgt tgtcttttca cggaattcat taacgaattc taatggacaa cgctcggtta
    34261 tgatcgtggc tgcttccaaa ggtgcaacag aggtgaagga caactggttg aatttggtat
    34321 gatcaatcaa tacaaatgtc tcttcggaat ttttcatggc taaacgttta acagctgcct
    34381 cttctggatc cggagtcgtg aatccttgtt caagatgggc accgttcatt cccataaatg
    34441 ctttattaaa atgaaaattt tttagttgtt ctatcgcatt agatcctaaa acagcattag
    34501 ttgccagctt tatcgttcca cctaaaataa tggtagcaag ctccaaatca actaaatttg
    34561 ccgcatgttg aacggaattt gtcactactg tgatctgttt tccttgcaga aaaggaatca
    34621 tttctaacgt agtagagcca gcgtctaaat aaatgacatc ttcgtcatta atggtttcag
    34681 ctgccgattt ggcgatttgc tgtttttcgt gaacgttttt gagtgatttt tcactcatat
    34741 tctgctcaaa attcaataat tgctctttct tagctccgcc atgaactctt tctagaaacc
    34801 cactattctc cagctcttgt aaatcacgtc ttatcgttga ttcagaagca ttcaaaaggt
    34861 ttacaagatc ttgtgatttc acgattttct gctgttcaag caagtctagg attttttgtc
    34921 tgcgttcctc tgtaagcatt ttcacgatca cctcaataca aataatagca tatttttttt
    34981 ctactagcaa tataaatcag tcaaaaacgt tcataaaaat tataaatcag tcaaaaaaaa
    35041 ataaaaaacc agtcagaaag actggttttt tatttttttg tctatcatca agccgtttta
    35101 tcgtttttta ttttcgcttc ttgttttttt catataaaca gaagcaggtt ttctttcctt
    35161 atgaagaaga taataataaa gtcccatccc gccaaacatg accaaaaaac cgatgactga
    35221 tcgaatagga aaattaggaa caaaaaagag acagacggat aataatgatg ccggaaccat
    35281 tattcgataa tagagttgtt tatccatttt cttcacctca tattttttgt aaagtaatca
    35341 attgttctaa ttctcggtaa tctaaaaatt gcacacgcag atgctgctca cctttcttga
    35401 catcgaattg gatacttcgc cgctttttct ttattcgttt gaaggtaaca tcagagagtc
    35461 tatgtttgat ttcctttaac ggtaattctg acagggattc tgaaggaaca tagattctta
    35521 aggataaaag atactcttga tatttttcat ctgttacctc tacttctaga tattccctaa
    35581 tataataaca ataagcttcg attccattat ccaaagcaac agtcggatcg ataactttat
    35641 agcacatcat gcgtgatcga ttctcgtcaa cccaaggaaa atacgcctga gcatttagtg
    35701 ttccgcgaac acgcctttct ttataatctc cttgttggat atcataactt tttgttacaa
    35761 aaaatgaagc attcttttta ggaacaggtt gcatttgtgc attctgatac tggacagatt
    35821 ggatcgtatg gtcagtgtaa atgtattcaa cgaatggcgg tttcaataaa ccgacaccat
    35881 tgtcccaagc aagatgatca aacccaagct ggtccctaaa ataggattga aacatttgat
    35941 tgtttggctt ttgccagtta aaggggtctc gataaagctg gatacatatg acttcgtttt
    36001 ctaattcctt cactttttct acttgttgga tgtcgagaaa aatcggttta gggatgattt
    36061 gatgataata gcgactataa tacatttccc aacacgaagt gaaacataaa ccttggtaaa
    36121 aaagatcgta tcctggaaat tggttgcaat cgactactac ttccccgttt tgttgtttca
    36181 ttttaggtaa atgttcgatt tcatcctttt tctcaaacaa tagccgttga gagatctgtt
    36241 ttgtattgtg atagataaac tcgctataag ctcgcatata ggcgaacacc ccatgagcaa
    36301 tcattttttt ctgaatgaag tctcgaatca aaaattgctt ttctttgaaa acagagatag
    36361 acaatacatt ttttatcaat aattgattat cttccaagcg aaaactacat tcgttctcgt
    36421 catttcctac aactaaccaa ctttcgtctc ttaccgatgc tagcattatt ttttcttgaa
    36481 gctttcgaag atcatacgga tccgcttgtt gtgtgaaaga gcggataaat gttggctgga
    36541 tcaacagacg tgtcaaaata gcccaatcgc ttatttcctg ttttttttct tcttcattta
    36601 agtctgtgag ctggatagtc atcaataatt tatcttcgcc aatcattttc tcacctcttt
    36661 caaatctttt tataatttaa ttataaccaa tgataaagaa aaactaaaac tttatgtctt
    36721 agaaaccaat ttggacgatt acatgataga ctaagtaaaa agaaacaaag aggtgtttac
    36781 aatggggttg aaatttgaac gtacagataa tttagataaa cttttcgaat catttgctgt
    36841 cgatccggaa aaaacagttg caccaaaaga agagatcgat cgatttctaa aaccacagcc
    36901 acaaaatgaa aagaaaaaag acaagaaaca aaagtaagtt aagctcaaaa aaagacttac
    36961 cagccaaact tttatgaaag agtttgactg gtaagtcttt tttattcttt ttatgattca
    37021 attgcttgtt cgattgctgc ccacgcttct tcttttccct gttttgtaac ggaagaaaag
    37081 agaataaacg tgtcattgcg atcaaaatcc aacgcttttt tgatttcgct ctcatgcttg
    37141 ttccatttac cacgagggat cttatctgcc ttagtggcaa caacaattac agggatatca
    37201 taatacttca aaaattgata catctggata tcttcttgag aaggcttatg acgcaaatct
    37261 actaaagaaa cgaccgcacg tagctggtct ctagtcgtta aatatgtctc gatcatcttt
    37321 ccccattttg ctcgctcagt tttggatact tttgcatacc catatcccgg aacatcgaca
    37381 aaatgtaatg cgttctcgat caaataaaaa ttcaatgtct gggtctttcc tggcttaccg
    37441 gaagtacggg ctaaattctt tcgatcaatc aatgtgttga taaaagaaga tttccctaca
    37501 tttgatcgtc ctgccagagc tatttctggc aattgtgtat ctggatattg ttttggtgcc
    37561 actgcactta tgataatttc agcttgatgg actttcatgg tctctctcct taacaaggtg
    37621 atgaataaag caagcggctg tcgcaaaagc caaaatgact tttacggcag cctcttttca
    37681 tcaacccgct tttttctctg aatctttata gattactgtt ggctcaccag acaattcagc
    37741 tgcttctttt gtgataatca ctttttcgat gttttcattt gaagggatat caaacatcac
    37801 atccatcatg atttcttcaa tgatggaacg aagtcctcga gcaccggtat tgcgttcgat
    37861 tgcttttttc gcaatggctc tcaacgcttc aggttcgaat tcaagttcgg tattatctag
    37921 agaaagaagt ttttgatatt gtttgactag cgcatttttc ggctcagtca agatccgtac
    37981 cagatcatct gttgtcaatt tctctaaagc tgccataaca ggtaatcgtc cgataaactc
    38041 agggatcaat ccgaatttta gtaaatcttc aggaatgata tgctgcatga cactttcgtc
    38101 ttcagaaagt ttttggtttt gtgtaccaaa tccaatcgtc ttttcgccca tacgattctt
    38161 cacaatcgtt tcgatgccat caaatgcacc acctacgatg aacaatatgt tcgtcgtatc
    38221 aatctgaata aattcttgat gtggatgttt acgtccgccc tgaggtggca cacttgcaac
    38281 agttccttct agaattttca gcaaggcttg ttggacacct tcgccggaaa cgtcacgagt
    38341 aatagataca ttttcgcttt tacgcgcaat tttatcgatc tcatcaatat agatgatccc
    38401 tttttctgca agttccacat tgtaatcagc agattgaagc aatttaagca aaatgttttc
    38461 tacatcttcc cccacataac cagcttctgt caaacttgtc gcatctgcga ttgcaaaagg
    38521 tacattcaat gtttttgcta atgtttgtgc taaaaatgtt ttaccagacc ctgtaggtcc
    38581 gatcaagcag atattgcttt tttgcagttc aacatcatct gtgttttctt gtgcttgctg
    38641 attgacacgt ttatagtgat tgtatacggc aacagctaac gagcgttttg cgcgatcttg
    38701 tccaatcacg tagttattca atacttcaag aatttctagt ggtttaggga cttcagtgaa
    38761 ttcgcgtaca gcttcttcat aaaattcttc atcaatgatt tctttacata ggtcgataca
    38821 ttcattacag atgtagaccc ctggaccagc tacgatcttt ttcacttctt cttgggtttt
    38881 cccgcaaaaa gaacagcgta cggtctcatt gctacttgga ttgtcataca tggtcttcac
    38941 cccttaactt gcaaaaagta tgcaagaaac tatcaaagac tttacagtct tttactatca
    39001 taacatagtt tagtaaaaag aaaaagtgtt taacaaagga tcaactgacc tatacctttg
    39061 cattttttac tcttaacaaa aaataaggaa ctgtgacaaa atcgtgtcac agtcccttat
    39121 ttcgaataaa caattttcta gaagtagctt cttcagaaat gatttattac ttgatttcta
    39181 ttctttcgct tctgtcgctg tacctgtgat caattcgatt gcttttttca ttgtcacatc
    39241 atgttccagc atatcttctg tcaacacgcg tttgatttgt tcgattggca tgttgtatgt
    39301 ttctgataat tcttggattt ctgcattgat ttcttcttct gttgcttgaa gattttcagc
    39361 agctgcaatt gcttcgatca caagatttgt tcttgtgcgc atttctgctt caccttcgaa
    39421 ttgtttatgc aagtcttctt ctgtagaacc agttaattga tagtacattt caggagagat
    39481 accttgacgt tgcatgttgt tcaagaattc gtccattgaa cgatgtactt catcatgaac
    39541 catcacgtgt ggcaattcaa cgatttctgc gttttcaaca gccatacgga tcgctgcttc
    39601 atcttttgca tcgtccgctg ctttttcttt tgtttctact aattctttgc gatatttttc
    39661 tttcaattcg tctaatgttg atacttcgtc atcaacatct tttgcgaatt cgtcatctaa
    39721 ttcaggcact tcttttgctt ttacttcatg gattgtcact ttgaagactg cttcttttcc
    39781 agcaagatct tctgcttgat aatcttctgg gaaagttaca tttacatcta gactttcacc
    39841 tgatttatga ccaactaatt gatcttcaaa acctggaatg aatgagcctg aacctaattc
    39901 aagtgagtaa ttttcgcctt ttccgccatc aaacgcttcg ccatctacaa agccttcgaa
    39961 gtcgattact actgtatcgc cattttcagc tgcagcatct tctttgataa ctaattcagc
    40021 ttgtgcttct tgttcacgtt tgatacgtgc atccacgtca gcatctgtta cttcacggtc
    40081 ttgtttttca acaactagat ctttatattg tcctaatttt acttctggtt tcactgttac
    40141 ttcagcagtg attacccagt cttgaccttt ttccatgctt tcaacatcga tttttggttg
    40201 agaaacagga tcgatgccag cttctttgac agcagcttca taagcttctg gtaatacagc
    40261 attcaatgca tcttcatata aagcttcttc accgtacata cggttgaata cttgacgaga
    40321 aactttccct ttacggaatc caggtacgtt caagcttttt ttcactttat taaacgcagt
    40381 tgttaatcct ttttggattt cgtcttgcgc aatcgtaaat tttaaaacac catcattcgt
    40441 gccttttttt tcaaatgttg cagtcattta attccctccg agtttagaaa ttcattttat
    40501 acatcaaaaa cgtttcatgc atacctttaa atagtacact aaccctttca aattgtaaac
    40561 atattgaatg gatagaatcc ttgtttttca taacattttt atctttttca ctgataaaat
    40621 ctaatggaag aagatcattt gctgcaaaat tttttctctt ttttttaaaa aatcttgttt
    40681 ttcatcttct gtaccttcat acatcgtttt tcctgtacac gcctctacag tcagttgaaa
    40741 ccagcgcttc gggtcttcga tgtatgtatc atagacagga taaacaattg cagattgcaa
    40801 cgtgaattct tcttttaaca cggaactaag cagcgcatct tcattcccgt aacgatctga
    40861 aaatacacat aattgctggt aacttgcctg ctgctgcggc tttggcagat cttttggtat
    40921 gactttgact aacttttctt caatcgtcaa atagaaaact tgatggcatt cgttcaattg
    40981 cctaagtgtc tccagtaatt ttgcccttgc taaaatatgg acctctggcg atacaataag
    41041 tttactcgct gtttggataa actcatgata aggaagctgt tcgatctcat caatagacgc
    41101 aagctgacgt gcaggttcca acgaaggaag ttcctccgat ttattgtgga gtgccttgat
    41161 cttctgcctc tccatttgtc cggataattc ttctgcaaat tggatttttt caatgacccg
    41221 ctgctcgaaa gcttcataaa aatctgtact tgctatcaat tttctagcat ataaaaaatc
    41281 ttgtgtactg attaacaagt caaaataaaa ttcagcaaac tcctcatttt gaagatactg
    41341 tttttcatgc aagagtgctt gcttcaatgc ttcttttttc tcgtccaact cgtaaagaca
    41401 aaaaacaagc aggctattag cctcaaagct ttctttcaac tcgtaagctc gttgaaataa
    41461 ttcttttgcc tgctgatatt gctggtttgc tagtgcttgt tgtgccactc gcattaaatt
    41521 ctcatatttt tctggaaaat caatcggctt cacgcagtgt cctcctcttg ctcatattca
    41581 gctcatgttc aatagtagca aaacaaaaaa agcatgacaa ttaaaaataa ctgaagcacc
    41641 ctctaaaagc tagattttag atctgacttt tagaaggtgc tttcaactgt tactgctttt
    41701 tattgctcat cagctgttga cttcctggtt gaacgctttg atcagattga tcgtaacaac
    41761 acttgtatta gtgaaaaaat cgcccagatg ttgctttttc tgattaaaga ctgctggaag
    41821 ataccctaac atcagcaaag gaaattttag aatgaaccgg caagcacctt ctctaactaa
    41881 aacggttgac cagctaagtt cttcttcatc aaagctgatg actcgaatac caaagatcat
    41941 tttcccaatc gtttggccat gattgaattt cgtcaataaa ataaaatacg ctagataaat
    42001 aagtaaggct gtgaatccgt agagactcag ataagaatct gaaaaattaa gccaacctag
    42061 atttttggca ataccaagtg ttaaacgcgt aatagctccg atacacaaaa gatcgaccaa
    42121 gaaggcaaac attcggataa aaaaacctgc atagaaatac ttaggaaaat catttgcttt
    42181 tggcggttca tttcttgtgt ccgtatactt tttccattta cgttgtttct ttttgatttc
    42241 ttcgggcgtc aaaggctctc tttcaaaaga gctcagtacc ttttgggaaa agttggagtc
    42301 aggtcctaca gcaggctgct gttgcttatc tttttcttgt tccttatttt catttgaaag
    42361 ctctgacatg cttactcacc tccgtaataa tacattgctt ttggtgattc cgctgtccct
    42421 agattctcaa gaacggataa gatctgacta gtctcagaag gcttcaatcc ctggaattct
    42481 gctagtttac ttcctaacca tgtactagca aacccagatg gcgtggaaga atattctact
    42541 agttccgcat cttcaagctg ttgttccttt cgtatagctt ttaaagcatc ttcaggaaat
    42601 cccaattcat cgactaaacc tacttctttt gcttggacac catcataaat ccttccatca
    42661 gcaatttttt tgacttcttc ttcagattta ttccgtccct cgctgacgat tgctacaaaa
    42721 cgactatatg cgctgtcgat atatgcttga agcaccgctt cttcttcttt tgtctctggt
    42781 cgcgttcctg aacccatatc tttcaacgct ccgcttttaa ctgttgtatc ttccacaccc
    42841 agtttttcta gaagtcctga ataattcaat cctgacatga tcacaccaat tgagccggtc
    42901 actgtttctt ctgttgcaaa gattttatct gcttgagcag aaatatagta gccaccgcta
    42961 gctgccatgt ttttcatgct gacatacatt gggatatcat gttctttacg aatcgtatcc
    43021 aatttcttag cgatttccgc actttcgtag acaccgccac caggagaatt tacttctaaa
    43081 aagatacctt tgactgttgg atcttcttca atcgccttca gttgttccat aaaattttta
    43141 tgattgtaac cttcagaagc aaataaacct gaagaccctc ccgcagcaat cgttccatct
    43201 actgataatt ttacgatttt ttgcgtactg tctccctctt ccaacacatt tggagctagt
    43261 tcttcatccc catataacca actgttcaat ccctcaattt gatcgttttc ctgaggctta
    43321 gtcaaactag ctgaaactaa cgaaaccaca aataatcctg cagcaatcag aactgctgcc
    43381 caacgtcttt tattcattct ttctcctttc taatacaagt tttttatgac gatcacagtt
    43441 tctgactgct cagaagtgtc gaaccgctct gctttttctt cccgcgcata cccggaaaac
    43501 gactcttttg ttaattcatc ttctaccgta aactcacgag cttgagcaac ttccaaggca
    43561 tcaggtgcga tttcttggat gctatcccag ccagtatcta aaaatatttt cgtatcatct
    43621 gatacaccag ctgatgcttc gaatttggac aattgttttt ttaacattcc cagtgtcatg
    43681 atctcaattt ttgaatccat ttttactcct cctctatccg attactttct attgtaccga
    43741 actcctgaaa aagatgatag ataaaaaccc attatttttt gacataaaaa ggacatttga
    43801 caaagaattt gatatatacc aatttatttt ttattctttt tttgttgaca agaacattcg
    43861 caaaaggtta tgattttaaa tgtttccaga taaaaaacaa aaaggaggat agttatacct
    43921 tttaggatag cgccaggtct gtgtaaacag atgacgagga gagggtttat cgaaagattc
    43981 ggcggatggc cctagggact gcactctaca gaaaatccac aaaaaatgtc tgcaaagata
    44041 aaacaaaagg attttcctgc agctggaagc attcatacga attcattata gaaagtagga
    44101 tgttttttat gtgcggaatt gttggaatga ttggattaaa aaatgtaaca ccaggattga
    44161 ttgacggtct agaaaaatta gaataccgtg gttatgattc agctggtatc tttgtctcag
    44221 atggcacaac tgattatctg gtcaaagcac aaggcagaat tcaaaatttg aaaaacaaaa
    44281 taaatattga tactacagga aatataggta ttggtcatac acgatgggca actcacgggc
    44341 aaccttctga agaaaacgcc catccacata cttcccaaag tggacgcttc gtgctcgttc
    44401 acaacggcgt aatcgaaaac tttgaagaac ttaaaattgc ttatttagca aatgaccact
    44461 ttattggtga gaccgatact gagattatcg ctcatctaat tgaaactttc gcgaaggata
    44521 ctacaacgca agaggcgttt ttaaaagctt tgcgggtcat caaaggttct tacgctttcg
    44581 ctttgattga tcggacagca cctgatgtta tttacgtcgc taaaaataaa agtccactat
    44641 taatcggact cggcgatgga ttcaatgtga ttgccagcga tgcaatggct atgcttgctc
    44701 atacgaagga attcgttgag attgaagatg aagagatggt taccgtcaca tcagaaaaag
    44761 ttattattca aaattttgca ggtgacatcg tagaacgttc ttcattcgaa gcacaagtag
    44821 atgcttcaga tatcgagaaa ggtacctatc ctttttatat gctgaaagaa atcgacgaac
    44881 agcctattat catgcgtcgt atcgctcaaa aatacgtaac agaagacaat cgtgtctctc
    44941 ttgatcaaaa gctggtcgat acattgtctg atagcgatcg aatctatatc gttgcttgcg
    45001 gaactagtta ccatgcgggg ttagcaggta aacagacttt ggaaaaattg acacagattc
    45061 ctgttgaggt tcatttagcc agtgaatttg gctataacac acctcttctt tcaaaaaaac
    45121 cattctttat tttcttgagt caaagtggcg aaacagcaga cagccgccaa gtgctggtaa
    45181 aaatcaaccg tctcggctac ccttcactta cgattacaaa tgttgctggt tctactcttt
    45241 cgcgggaagc atcctttaca ctgctattgc atgctggacc cgaaatcgca gtagcatcaa
    45301 cgaaagctta tactgcacaa atagctgtac taactttatt agccaaagct atcggtgata
    45361 aaaaagaatt tgaaacttct cttgtattcg atatcactca tgaattgagt ttagttgcta
    45421 atgcgatgga atcggtcatc gcccaaaaag attatttaga agagttggca gaagtatatc
    45481 tcagcgatac aagaaatgcc ttttacattg gacgtggtgc tgactacaac gtttctcttg
    45541 aagctgcttt gaaattgaaa gaaatcagtt atatccaggc agaaggtttt gccgctggcg
    45601 aattgaaaca tggaacgatt gctttgatcg aagaaggaac accagtgatc ggaatcatca
    45661 gtgaagaagt gactggtgcg catactcgag gaaacctgaa agaagtcgaa agccgtggcg
    45721 ctaaaacact agttattgtc tcagagggat tagaaaagga aagtgaccag ctggtgctac
    45781 caactgtcca cccttatcta actactctaa ccacagtcgt accgactcaa ttacttgcat
    45841 attacgcaac gctattacgg ggattcgacg ttgacaaacc acgtaattta gcgaaatcag
    45901 tgacagtaga ataataaaag aacaaggacc agtgtcagac atctgacact ggtccttgtt
    45961 cttttatttt ttatgaaaat atctcttaat ccagtccgat ttcttctttg actactgccg
    46021 cgattttatc gacatagtaa ttaactttct catcagtagg cgcttctgcc atcactcgaa
    46081 gtaatggttc tgtaccggaa ggacgaacta ggattcttcc ttctgatccc atttcagctt
    46141 ctgcctcttc aatcactttt ttgattgccg gaacatccat cgcaccgttt ttatcactta
    46201 cgcggatatt cactaatttt tgcggataga ttgttacctc tgctgcaagc tctgataatt
    46261 tcttacctgt ctgtttcatg atattcagta actgaattcc tgaaagcatc ccatctccag
    46321 ttgtgttaaa atctaagaaa atcatgtgcc cagactgctc gccgccaaag ttataatcgt
    46381 ttttgcgcat ttcttctaca acgtaacgat caccaacttg tgtaacgaca tctttcaaac
    46441 cgattccttc caccgctttg tggaatccta agttactcat gacagtcgta acgatcgtat
    46501 cttttttcaa tcgatttttt tctgccaagt atttagcaca gataaacatg attttatcac
    46561 cgtcgacaat gtttccaagt tcatccaccg caataatacg atcgccatcg ccatcgaaag
    46621 ctagtccagc atctgctcct ttttcaacga ccatctcagc taaacgttct ggatgggtag
    46681 agcctacgcc gtcattgata tttaacccgt ctggatttgt gcccattgta taaaaatctg
    46741 tttcaagatc ggcaaacaaa cgattaacac ttgttgaagt tgctccgttt gctgcatcga
    46801 cacaaatggt caaaccggaa aggtcaccgt tgatcgtttg tacaaggaat tgagaatatt
    46861 tcaataagcc ttctggaaat tcttctacag ttcccaatcc ttcagctgat ggacgaggca
    46921 attcatccac ttcagcatct aataatgctt caatttctag ctcttggtca tctactagtt
    46981 taaaaccatc tgcaccgaaa aatttgattc cattatcttg tgctggatta tgagaagcag
    47041 aaatcatgac ccctgcgctt gctttttgca aacgtgtcag ataagcaaca cctggtgtag
    47101 agatcacacc tagctggaac acttcgatac ccaccgataa aagtcctgaa atcagcgctt
    47161 cttctaacat ttgacctgag attcttgtat cccgccctac taacacgcgt gggcgttttc
    47221 cttcttcttc atgctggctt aggacataac ctccgcaccg tcccagctta aatgcaagtt
    47281 ctggcgtaag ttccttgttg gcttcaccgc gtacgccgtc tgttccaaaa tatttaccca
    47341 tagttgtaaa attactcctt taacttaatt ttctgaggaa tttgttctgc tcatttgtgt
    47401 tgattcgctt gtttctgatg tttcttctgt acttgtggtc gagctgcttg tcccagattc
    47461 cgaactggaa gaaatggttg ttgtcgatgg ttccgttcct gaatcagcag atgaaatact
    47521 tctactcgta cttgtatttt cttgtgtccg actgctcgtc gaagcagagc tactgcttga
    47581 cgtttgcaac acgggtgtaa tctccacact aactgattcg ggcttgatac ttaacccctc
    47641 ttctactggt atttcaattt tacgagttgt tcgatgattg atacctgaga cattgatcgg
    47701 tacagcaata ctgtcaccga tcgatgcaag caaatcgcta gagccgctta cttctgcttc
    47761 cagttttgaa aaactgaaat catagctttc taccccggca gctggtgttc cttgctgtat
    47821 cccataaagt cgtaccgact tgcttggctt gatcgaatca gctctcactg ttacttgcac
    47881 tggatcagag acgatactta atacttcccc tgctgcattc agcgcctgta ttgggacctc
    47941 actattaatc ccatcatctg tgaccatcga agcgtccaca tcagctacta ctcgtttgat
    48001 ttctgccaat gttttgtcac ctgtagtgat agagactttt ttaggactaa cggaagtatc
    48061 atcaagttca tatccagatg gtgtgaacgt tgaaggaatc aacgtttcca catcgaaatc
    48121 ttttattacc tttttctcaa ccgttactgt aatagtcgat ggttcgatct ttgctgtgac
    48181 agcactgctc aaattttgaa tttttagcgg aacttcatgt gttccttcgc ccagcttagt
    48241 gatatctgct gtgacgcgga acatccgtgt atcttcgttt gcctctgcat tcaactgaac
    48301 tcggtttgca ctggaaagtt tgacagtcac tgcattttca tatccatgga tatagtagcg
    48361 ctttgaatca taagaaatct tgatcggcac ccccgtaact gtttgattat acgcttcatt
    48421 tccagaaagc gtatttggaa cggactggcc atttgcattg aagtacagcg caatactgaa
    48481 cagcaatgca ataaaactgt aaagaatgct tgtccgtttc tcttttgaga tcatttgcga
    48541 tcccctccct tagtcatacc gtctaggaaa gattgaatca cgtttttctt gttttttgtt
    48601 ttctcttcag caattagttc tctacgcaag attgccaaat attcttgctg ggataagcca
    48661 gccatcagtt cattatctaa cgtgatgctg acgtccccgg tttcttcaga gacaacgatg
    48721 gtaatcgcgt cactgacttc gcttataccg acagctgccc ggtgtcgagt cccgaattct
    48781 ttagggatca acatactttc tgatagagga agataggcgc ttgctactgc gatctttcct
    48841 tcttttacaa taactgcacc gtcatgcagc ggtgtattag gaataaagat attgatcagc
    48901 agctccccag tgatatctgc atctaaagca atccctgtct caatatactc atctaatcca
    48961 gtatgacgtt cgatagtgat caacgcaccg atttttcgct tggacatata ttggatggct
    49021 ttgtcaaaag acaagatcat cttctcatct tcctgctgtt cgctttttga ttgtttgaaa
    49081 agcgaactgc gtccaagatg ttccagtcct ctccggattt ccggctgaaa aatcacgata
    49141 gcagctatca ccccgtacgt aatgacttgg ttcatcagcc aagacaaggt gtgcagacca
    49201 atgatttccg ctacgattcg gataacaata aaaatagcta cacctttcag aagctgaatc
    49261 gcttttgtgc ctcgcagcag ttggatcagt ttgtatacaa gataccagac aaccagaata
    49321 tcaagtatgt tcaccaaaaa attcagagag aacaagtcac cggaaaacat ttgctgccaa
    49381 tagtccaaat taaaaagttc cccgatttga aatgacataa aaagcctctc ttctcttttg
    49441 agatttcctc tctagtatat catatgtttt aattttagag gctgatatgc tcgtattttt
    49501 cttgagaaaa acgcataatt ttcaagaaaa ttgcaagtat gcgttttatt tttctctgca
    49561 ataaatattt ttaaacttca gagaattatt cattatattt tttctgttat ttttcctttt
    49621 tttcttttgt agcttgttcc atttttttac gtcgttctgc tctggcagct cttctagcag
    49681 ctcttctttc ttctgcttca aggtccgtcg ttttttcttt tctagtctta acgggtacat
    49741 cgatagattc ctctggttca agtcgtttct tgattttttc taattctccc gtcagtgcag
    49801 catagttgta aaaacgtgtt ttagcgtcgt ggacagtctt ttcaaataaa gcttttgcaa
    49861 gatttggatt tgcgttatct agcgaggaaa agcgaacttg tttcctcatg aaatcaggca
    49921 tagcagagaa atcaggtttt ttgtagtcca aagtcattgg gttcttgttt ttttcgacca
    49981 ttgtagggtt atatcgatat aatgaccaat aaccagaaga aacagcttct tttgcttctt
    50041 taagcgattc tttcattccg ccaagcaagc catgtgtgat acaaggcgta taggcaataa
    50101 tcagagaagg accaggatac ttttctgctt cttcaaatgc cttgatcgtt tgcatttgat
    50161 tggcacctga agcaatttgc gccacataaa catttccata tgtcatcgcc atcattccta
    50221 gatctttctt tgaagcatac tttccactag ccgaaaattt agcgattgcc gaagctggtg
    50281 ttgcttttga ggtttgaccg ccagtattgg aatagacttc gttatccaaa acaaggatat
    50341 tcacgtctgc tccgctggca agtacatgat cgatcccgcc aaaaccaatg tcgtaagccc
    50401 atccgtctcc accaatcatc cattggctgt tttttacgaa tagatccttt ctcttgtata
    50461 tatcctccag ttcagggaaa attgatcgtt cgctttcgat cgcagcttgc agttttgctg
    50521 ctctttgctg cgttccttca ctctcaaaca tgtgtactaa ccagtcttcc atcaattctc
    50581 gtagttcttc tgatactttt ggcaatactt ctttgattga acttgccaaa gcctcgcgac
    50641 gagtctgtgc cgctagaagc ataccataac caaattcagc attatcttcc aataaagaat
    50701 ttgaccatgc aggcccttga ccacattcat tggtcgtata aggagaagca ggagaagcac
    50761 cgccccaaat agaagaacag cctgtcgcat tcgcgatcat cattcgatca ccgaacattt
    50821 gtgtcaataa ttttacataa ggtgtttcgc cacagcctga gcaagcgccc gagaattcaa
    50881 gaagcggttg attgaattgt gtagacaaga cagtattctt tcctttgact ggatttgctt
    50941 tttgtcttaa tgtcattgca aaagcccaat tcacagcttg ttctttctgt tcttcataag
    51001 gcttcatcac taaagctttt tcttttgcgg gacaagcctc tacacacaga ccacaacctg
    51061 tacagtcttc cactgaaact tggatacggt attttacgcc gtctgcgcct cgcatttctc
    51121 tcacgataaa tccttctggc gcttcttcca tttcctcttc atctgctaaa aatggacgga
    51181 tggcagcatg aggacaaaca aaggcacatt cattacacat cgtacagcga tcactaatcc
    51241 actcaggtac ttctaaagcg acgccccgct tttccataga agccgttcct aaaggcattt
    51301 cgccagttgt cattccattt gctacaagtg taccaacaga gagttgattt ccttcctgtg
    51361 cattcactgg ttcaagtatt tcttgtatat aaccagtgtt ccttttattg attttttcag
    51421 gcatctccaa cgttctccaa tggtctggga tcgcgacttg atgaagcagt tcggtcgtcc
    51481 gatcgattgc ttgtatgttt ttttctacga tagccattga tttatgtcca tagcttttca
    51541 gggcttcttc ttttagcagc ggaagcacct catcaaaagg aatgatgtca gctaatttaa
    51601 aaaaagccgt ttccattgcc gtattgatcc ggcgtcccaa accgacttct tgggccaatc
    51661 tcatggcatt gatcgtatag aatctaatgt tattttcagc caagtaacgt tttaatttta
    51721 agggcagatg cgtttctaat tgttcgtcgc tccaaagagt attcaataaa aaaatgccac
    51781 ctggcttcaa tcctttgacc aagtcatagc tatgcaggta agctggtgtg tgacaggcaa
    51841 caaggtccgc atgctcgaca agatacgctg aacgtatcgg cgtatctcca aaacgaagat
    51901 gagagacagt cagaccgcca gattttttcg aatcataata aaaatagcct tgcgcatatt
    51961 tatcggtgtg atctccaata atcttgatag ctgatttatt tgctccaact gttccgtcag
    52021 atccaaatcc ccaaaacttg gcctggaatg tttgcggttc tgtcaaatcc agactttcct
    52081 ttggttccaa agattgataa gtcacatcat ccacgatccc tatggtaaac cgttttttgc
    52141 gtatgcttgg gtcttttttc aattcatcaa aaactgctga gatttggtcg ggagtcacat
    52201 ctttagaccc caatccgtag cgaccaccaa taacagccgg gcgaagttca gaatcatata
    52261 acgcactttg aacgtctaat aagagaggtt ctccacctgc ccctggttct ttacttcgat
    52321 caagaacagc aattgttttt actgtatgag gcaacttttg cacgaatgtt tccactggaa
    52381 aaggacgata aagatggata ttcaaaaaac ctgttttccg tccgtttgca ttcaagtaat
    52441 caatcgtttg ttcaatcgtc tgtgcaactg atcccataga aacaatgact tcttccgcat
    52501 cgtctgctcc gtaataagtc accaagtcat aagaagttcc tcgtaatcgg ttgatctctt
    52561 tcatatattt ttgaacgatt tcaggtaatt tatcataata ggggttgatc gtttcccgtt
    52621 gttgaaaatg gatgtctgga ttctggttcg taccactaac agtcggatga ttgggattca
    52681 tccctcgttt acgaaatgaa gctaatttct cctgattgat cagaggagct aattcttcat
    52741 attccaaaac ttcgattttt tgaatctcgt gactcgtacg gaatccatca aagaaattca
    52801 aaaaagggac ttctccttca atagaagcaa gatgggcaac aggtgctaaa tccatcactt
    52861 cttgtacact gctttcagct aacatagcaa atcctgtttg tcttgcagcc atcacgtctc
    52921 cgtgatctcc gaaaatattc aacgcatttg tcgtcactgc ccgactagca acgtggaaaa
    52981 cacttggcag tagttcccca gcaatcttgt acatattcgg tatcatcaaa agcagccctt
    53041 gtgaagcggt atatgtagtt gtcagtgcac cagttttcaa tgatccatgg accacaccag
    53101 ctgctcctgc ttcggattgc atttctacta cttttactgg ttgaccgaat acgttttctt
    53161 ttcctgctgc tgaccattga tctactaatt cagccatggt cgaactgggt gttattggat
    53221 atattgcagc aatctcggta aatgcataag aaatatatgc ggctgccgta ttgccatcca
    53281 ttgttttcat ttttcgcatg attcatcatc cttgttcata ttctctctta ttatctgttc
    53341 cattataacg taaaacatgc catttttttc ttttatttat aaaaatattt tacatgtatc
    53401 tatttgaatt ggtcatctaa tttttagaca aacagtctaa atcgttgcct ttttttgtca
    53461 gacatgtata aactataagc gaaagaggtg ttttaacatg gatatatcag tgattgatgc
    53521 aacgaaaaca aatacacaaa aaggaatcct ttatggttca tcgaatgctc ctaaaaaaat
    53581 ggtcgaattc atcaacttag cttgtccgta ttgccgacaa tggtttgaag aatcttatga
    53641 gctattagaa gaagcagtcc aaagcgggca attgcagcga gtgatcaaat tgttcgataa
    53701 agaaaaagaa agcttacagc gagggaacgt gatgcaccgg tatctcacaa tcagcgatgg
    53761 ccaaaaagcg atcaaagaga tcaaacaaat attcgatact caagacgagt ggaaacatct
    53821 ttctctccaa gaagtagcgg attttgcagt agataaacta aagctgacag aacaaaaaga
    53881 cgaacagctg agccaagctg tcatcaacga agctgagcaa gcacatattc gatttgttcc
    53941 aactgtcatc ttgggtaaag aaatctttga tgaatctatt tcaatagagg aattaaaaga
    54001 attgatccaa acaaaataaa aaaataagga gcgtgggaca aaagtaaaga acacttttgt
    54061 ctcacgctct aaacacgtat aaacggcgga agcagaagca actccttctt atttcttgga
    54121 gttaaacgct tctgtcccag cctccttatt ccgaataaat ggtgtccaaa agcttgcatc
    54181 tgccagatta tctcatttct tatgacaagc taagcaaatt atctccacca aataatttat
    54241 tcatattttt gacttgcgca tactaactaa ttcttaaatt ttcatacaaa atttctcaat
    54301 ttcccttaac gagtaatatt tatgtacggt gattctcact agtatcccaa tcacttttta
    54361 agttatcccg atttcaattc tacttcaaaa atagttgctt ttatgtatgc tgttagttga
    54421 ttagatggtc atttgttgag ctaggtcgtt tattttaaac aagttgtttc tttagcttat
    54481 acctatctcg tctaccaaac gcaagatggc aaacacaaat gcatacgcat ctgtatttgc
    54541 cactttgatt cgtataaagc taacaactat taactcctct cagctaatag ttgctctctt
    54601 ttttattcag attcattttt gctgatcaca gcctagtatt tcaatggttt tgaacactaa
    54661 accaaattgt tccattacaa cattcactgg ctgatgaaat ggattagtag atttcgatta
    54721 ttcaaagcga ttttctattg gtggatcgtg ttcccaacta ataagacgga ttccaaacct
    54781 atcgtacaga tcttctaaac cacttataaa ttttgcacct atttcaggtg ttttattgcg
    54841 tggatattct attgttacgc cattaaatgg ataccaatta ggattaggct ctcttttttt
    54901 ctgtacatct cccatagaat agttagcact ttctgggaca taatatattc ttcgaccatc
    54961 ctctaattca tctaataaga tatttcgtga tcgtctatca cttgctaaat gtagacgcca
    55021 cgtgcgatac catgccatgc tacctgcatc tgcagaaaat ccatcaaata atgcaacaat
    55081 tgtatcttct atcacaatcc tttccccatc tacttcatat tctaatctaa aatcaaactc
    55141 ccctcgggta atttctggtc ttggtggctt aggacccaat attattctac ttaaaaccgc
    55201 attcgttccc agatgaaaca cagctataac aacaataatg attaatattt tgtttctatt
    55261 tgataaattt ctcattattc gcacatcacc tctacattct cacatattag ttcgtaatac
    55321 tcctttaata tcaaaatatc tactggtcgt aataatattc gctatgaatt cctactactc
    55381 gtataagaaa ggccaaatca tcagctttta cttgctgatg atttggcttg tttctattta
    55441 tcgtaattgt tttctaatca ccaaaattgt taacaatcgg ttcagatatt tcccagttga
    55501 ttaaggtaat tccgtattgt gtcaaaactt cttgcgcttc tccgaaatta agtacagttc
    55561 ttatgtatcc actttctcct aatataaagt ctacctctct tttaaaacct tcctcgagat
    55621 ttctaagggc tatatgtggt tttaatgaca ttgattgtac attttccccc atataatatt
    55681 gcgcacttcc tcgactaaaa tagattccta gatcgtcccc aaaaggtaga tcttctctac
    55741 cactagctaa tctacttctc catcttcgtt ctcttttcat agaacctgcg ctgaactcac
    55801 acccgttaaa ctcagctatg acagtatctt caattatgtt aatctgtcca tctagttcgt
    55861 attcaatcct aaatggaaat tctccatagg tgatttccgg ttcgggtatt ttaggtgaga
    55921 ttaatgcaaa gaaaggaaat attaagcttg gcaacatcaa aaaaactcct cctatgatca
    55981 caattcccga tgtaatccaa aatataattt gtacaattct cattgatcca ttgtattcca
    56041 ttttattccc cctattacta ttcatatccg cctatctata tcgatcttcc aatgcagaga
    56101 taattgcttc cataccttga ttttttactg agttacctat gcgagatatc attctccact
    56161 aaggtgcatc atattgtcta tctaacatga ttaattctcc aataggtgta tactcctcca
    56221 aaaacaacat ttaatgcatc tccctcgaca acataagcta ccatgtttgc tgtatatgtg
    56281 tttgagtcta attcataagc agataaattt actgtcgctg gattaaatat aatcgcattc
    56341 gtatttatag ctactgaatt t
//
LOCUS       DAPBBR010000016        53767 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPBBR010000016 DAPBBR010000000
VERSION     DAPBBR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.016"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            7..729
                     /locus_tag="RD488_000957"
     CDS             7..729
                     /locus_tag="RD488_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7657051.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            787..2826
                     /locus_tag="RD488_000958"
     CDS             787..2826
                     /locus_tag="RD488_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDT7657052.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2935..4086)
                     /locus_tag="RD488_000959"
     CDS             complement(2935..4086)
                     /locus_tag="RD488_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDT7657053.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4240..4770)
                     /locus_tag="RD488_000960"
     CDS             complement(4240..4770)
                     /locus_tag="RD488_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7657054.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4869..5219)
                     /locus_tag="RD488_000961"
     CDS             complement(4869..5219)
                     /locus_tag="RD488_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HDT7657055.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5376..6905)
                     /gene="ahpF"
                     /locus_tag="RD488_000962"
     CDS             complement(5376..6905)
                     /gene="ahpF"
                     /locus_tag="RD488_000962"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDT7657056.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6915..7478)
                     /gene="ahpC"
                     /locus_tag="RD488_000963"
     CDS             complement(6915..7478)
                     /gene="ahpC"
                     /locus_tag="RD488_000963"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDT7657057.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7622..8284)
                     /locus_tag="RD488_000964"
     CDS             complement(7622..8284)
                     /locus_tag="RD488_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7657058.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8468..10114
                     /locus_tag="RD488_000965"
     CDS             8468..10114
                     /locus_tag="RD488_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDT7657059.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10105..11187
                     /gene="uxuA"
                     /locus_tag="RD488_000966"
     CDS             10105..11187
                     /gene="uxuA"
                     /locus_tag="RD488_000966"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7657060.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11295..12848)
                     /locus_tag="RD488_000967"
     CDS             complement(11295..12848)
                     /locus_tag="RD488_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7657061.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12996..14284
                     /locus_tag="RD488_000968"
                     /pseudo
     CDS             12996..14284
                     /locus_tag="RD488_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14410..15489)
                     /locus_tag="RD488_000969"
     CDS             complement(14410..15489)
                     /locus_tag="RD488_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7657062.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15592..16032)
                     /locus_tag="RD488_000970"
     CDS             complement(15592..16032)
                     /locus_tag="RD488_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7657063.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16089..16499)
                     /locus_tag="RD488_000971"
     CDS             complement(16089..16499)
                     /locus_tag="RD488_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7657064.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16679..17113)
                     /locus_tag="RD488_000972"
     CDS             complement(16679..17113)
                     /locus_tag="RD488_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7657065.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17213..18061)
                     /locus_tag="RD488_000973"
     CDS             complement(17213..18061)
                     /locus_tag="RD488_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7657066.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18450..20216
                     /locus_tag="RD488_000974"
     CDS             18450..20216
                     /locus_tag="RD488_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDT7657067.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20318..21577
                     /locus_tag="RD488_000975"
     CDS             20318..21577
                     /locus_tag="RD488_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7657068.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21724..23025
                     /locus_tag="RD488_000976"
     CDS             21724..23025
                     /locus_tag="RD488_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7657069.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            23028..23879
                     /locus_tag="RD488_000977"
     CDS             23028..23879
                     /locus_tag="RD488_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7657070.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23892..24707
                     /locus_tag="RD488_000978"
     CDS             23892..24707
                     /locus_tag="RD488_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HDT7657071.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24858..26024
                     /locus_tag="RD488_000979"
     CDS             24858..26024
                     /locus_tag="RD488_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7657072.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26254..26901
                     /locus_tag="RD488_000980"
     CDS             26254..26901
                     /locus_tag="RD488_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7657073.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26985..27929
                     /locus_tag="RD488_000981"
     CDS             26985..27929
                     /locus_tag="RD488_000981"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HDT7657074.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            28064..29515
                     /locus_tag="RD488_000982"
     CDS             28064..29515
                     /locus_tag="RD488_000982"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HDT7657075.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKEIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29536..30372
                     /locus_tag="RD488_000983"
     CDS             29536..30372
                     /locus_tag="RD488_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7657076.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30372..31031
                     /locus_tag="RD488_000984"
     CDS             30372..31031
                     /locus_tag="RD488_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7657077.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            31157..31846
                     /locus_tag="RD488_000985"
     CDS             31157..31846
                     /locus_tag="RD488_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657078.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31852..32808
                     /locus_tag="RD488_000986"
     CDS             31852..32808
                     /locus_tag="RD488_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDT7657079.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32852..33364
                     /locus_tag="RD488_000987"
     CDS             32852..33364
                     /locus_tag="RD488_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7657080.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTIETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33620..34168)
                     /locus_tag="RD488_000988"
     CDS             complement(33620..34168)
                     /locus_tag="RD488_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7657081.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34257..35438)
                     /locus_tag="RD488_000989"
     CDS             complement(34257..35438)
                     /locus_tag="RD488_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDT7657082.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(35674..37182)
                     /locus_tag="RD488_000990"
     CDS             complement(35674..37182)
                     /locus_tag="RD488_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDT7657083.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            37341..37532
                     /locus_tag="RD488_000991"
     CDS             37341..37532
                     /locus_tag="RD488_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657084.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37735..38652
                     /locus_tag="RD488_000992"
     CDS             37735..38652
                     /locus_tag="RD488_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HDT7657085.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38645..39718
                     /locus_tag="RD488_000993"
     CDS             38645..39718
                     /locus_tag="RD488_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657086.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39866..40384
                     /locus_tag="RD488_000994"
     CDS             39866..40384
                     /locus_tag="RD488_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657087.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            40365..40757
                     /locus_tag="RD488_000995"
     CDS             40365..40757
                     /locus_tag="RD488_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HDT7657088.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40833..41768
                     /locus_tag="RD488_000996"
     CDS             40833..41768
                     /locus_tag="RD488_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HDT7657089.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41901..42680
                     /locus_tag="RD488_000997"
     CDS             41901..42680
                     /locus_tag="RD488_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7657090.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42673..42990
                     /locus_tag="RD488_000998"
     CDS             42673..42990
                     /locus_tag="RD488_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7657091.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            43234..44844
                     /locus_tag="RD488_000999"
     CDS             43234..44844
                     /locus_tag="RD488_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7657092.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            45001..45849
                     /locus_tag="RD488_001000"
     CDS             45001..45849
                     /locus_tag="RD488_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7657093.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            46080..46559
                     /locus_tag="RD488_001001"
     CDS             46080..46559
                     /locus_tag="RD488_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657094.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            46592..48820
                     /locus_tag="RD488_001002"
     CDS             46592..48820
                     /locus_tag="RD488_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7657095.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            48949..50592
                     /locus_tag="RD488_001003"
                     /pseudo
     CDS             48949..50592
                     /locus_tag="RD488_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
     gene            complement(50665..51210)
                     /locus_tag="RD488_001004"
     CDS             complement(50665..51210)
                     /locus_tag="RD488_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDT7657096.1"
                     /translation="MKLSEKELKDQLTEIVNNILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(51233..51718)
                     /locus_tag="RD488_001005"
     CDS             complement(51233..51718)
                     /locus_tag="RD488_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7657097.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(51708..52520)
                     /locus_tag="RD488_001006"
     CDS             complement(51708..52520)
                     /locus_tag="RD488_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HDT7657098.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(52659..>53767)
                     /locus_tag="RD488_001007"
     CDS             complement(52659..>53767)
                     /locus_tag="RD488_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDT7657099.1"
                     /translation="ILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAHS
                     MGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKVV
                     HMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTSM
                     AQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLPE
                     NTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLIE
                     TINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELPR
                     LNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        17902 a         9780 c        10381 g        15704 t
ORIGIN      
        1 tctattttgt tactgcttac attagtagtt ggctattttt cgattgagtt tatccatgga
       61 ttttcgtctg caaaacagag ttcaactgtg aaaaaggtag agccgaaaag tatccctacc
      121 acactaaatg tggctttgat tggttcagat gctcgttcga aagacgaaaa cggtcgctcg
      181 gattcacttc tggttgcaca atacaaccag aaaacacaac aagcaaaact gatctctatc
      241 atgagagatt catatgtcga tattccaggt tacggaatga ataagataaa tgcagcttac
      301 tcttatgggg gagttgattt attaaatcaa acattaaagg aaaatttcaa atttgaagct
      361 ccctattatg caagtatcac atttcaagat tttatcgatt gcgttaatga actgtttcct
      421 ggtggagtca agatcgatgc agaaaaatct ctagatttag atggcgtata tataaacaaa
      481 ggagagcaag tgatggatgg taatacttta ctccagtatg ctcgatttcg ggaagacaaa
      541 gaaggagact tcgggaggat cagaaggcag cagcaagtga tcaaagctat ctctcagcag
      601 ctgaaagacg taacttcaat attcaagcta cccaaagcgg ttgggaaatt acttggtagt
      661 atccaaacga accttccaga aagtgtgctt ctggattgtg gtatggattt cctcaaagac
      721 atatgttaga ataaacaggt ataaatagtg aaataaagga atgacaagca agagaaggag
      781 gaaaaaatga aaagaagtga caagcacggc aaaaatcgaa caggcgctta tattgccggc
      841 gcagtgatct taatagcagc tgcgggtggc ggttattttt actaccagca ctatcaagaa
      901 acccaagcag tagaagctgg agaaaagaca gttgagcaat ttgtccaagc tttgaacaag
      961 ggagattata acaaagctgc agaaatgaca tcaaaaaagg cggcaaataa aagtgcatta
     1021 tctgaaaaag agatcttaga taaataccag aatatatacg gtgctgctga tgtcaaagga
     1081 cttcagatat cgaatctaaa agtagataaa aaagacgatt ctacttacag tttttcatat
     1141 aaagcaaaga tgaatacctc attaggtgaa ttgaaagatc tttcttataa aggaacatta
     1201 gacagaaatg atggtcaaac cacgatcaac tggcaaccca acttggtttt tccagaaatg
     1261 gaaggaaatg acaaagtaag cctgaccaca caagaagcag caagagggaa tattatagat
     1321 cgaaatggtg aaccattagc aacaacaggc aaactaaaac aattaggagt cgttccaagt
     1381 aaacttggag atggaggcga aaaaacagcc aatatcaaag cgattgcttc ctccttcgac
     1441 ttaacagaag atgctatcaa tcaggcgatt tcacaaagct gggtacaacc cgattacttt
     1501 gtcccattga aaatcattga tggagcaacg ccagaacttc cagctggagc taccattcaa
     1561 gaagtagacg gcagatatta tcctttgggt gaagcagctg ctcagctgat tggttacgtg
     1621 ggagatatca cagcagaaga tattgataag aatccagaat taagcagtaa tggaaaaatc
     1681 ggtcgctcag gtttggagat ggcttttgat aaggatcttc gtgggacaac aggtgggaaa
     1741 ttaagcatta cagatgcaga cggtgtagag aaaaaagttc tgatcgaaca tgaagttcaa
     1801 aatggcaaag atatcaaatt gacaatcgat gcgaaggcac aaaaaacagc ttttgacagt
     1861 ctaggaggaa aagctggatc aactgttgcg acaacgccaa aaaccggtga tcttcttgcg
     1921 cttgctagct ctccaagcta tgatccaaac aaaatgacaa acgggatctc acaagaagat
     1981 tacaaagctt atgaagaaaa tcctgaacat ccattcatca gccgatttgc gacaggttat
     2041 gctcctggat ctacgtttaa aataattaca gcagcaatcg gtctcgacaa cggcactatc
     2101 gatccaaatg aagtgttgac gatcaacggg cttaaatggc aaaaagacag ttcttgggga
     2161 tcttttcaaa caacgcgtgt cagtagtgat gtatcacaag tagacttaaa aactgctttg
     2221 atctattccg ataatatata tgcggcacaa gaaacgttga aaatgggtga gaaaaaattt
     2281 cgtacaggct tagataaatt catttttggt gaagaccttg atttgccaat tagtatgaat
     2341 ccagcacaaa tttctaatga agatagcttt aactcagata tcttgctagc tgatactgga
     2401 tatggacagg gcgaacttct aattaatcct atccagcaag cagcaatgta ttctgttttt
     2461 accaacaatg gcacacttgt ctatcctaaa ttgattgcag ataaagagac aaaagataag
     2521 aagaatgtca tcagcgaaac agcagtacaa acgatcgtgc cagatctgag agaagttgtg
     2581 caagatgtaa atggtacagc acattctctt tctgctttag ggattccgtt ggcagcgaaa
     2641 actggtacag cggaaatcaa agaaaaacag gatgtaaagg ggcaagagaa cagtttcttg
     2701 tttgctttca atcttgataa ccaaggttat atgatggtca gcatgttgga aaataaagaa
     2761 gatgatgatt cagcaaccaa acgagcatcg gaactattgc aatacctcaa ccaaaattat
     2821 caataaaaaa ttgcttttta agtacagtaa aaggactgtg gcgttatcgt cacagtcctt
     2881 ttttcaaata aacggttttc acgatgtctc tttcacaact tctttttgat ttactcacac
     2941 ttcataaact ttttttgtaa aatatttgag aacaagtgga gaaataagtg tacttaataa
     3001 aatcacgata actaaaggtg aatagtactg tggttcgatc aattgacttt gctgtccaat
     3061 ttgtaaaatg atcaaagcca tttctccacg cgaaatcata ccagcaccga ccatcaatga
     3121 actatgttga gaaaaaccgg caatctgagc accaaaataa cctccaagca atttggtcaa
     3181 aatcgctaca agcgtcaata tagaaataaa gagtagttgt tcactaaagt cagaaaaatc
     3241 aacttctaat cctacactga caaaaaatac tggtataaat actgcatatc ctaaagcctc
     3301 tacattgtgg tatacttctt ctttaacctt tgtctgactg acagctatcc cagcaaaaaa
     3361 agcaccaatg acagagctaa gcccaacaag atccgctacg taagacattc ctaaacaaat
     3421 aactagcgat acgatgataa tagaagaatt tgcgtacact ttttctgcaa atgaaagtag
     3481 gaaaggcgca atccatttga ctaataagaa aataaaaaca aaataaatta gctgttcaat
     3541 caaaacaagc ggtaaagaag cattgctaga agcttccccc gttagaaaag ataggctgaa
     3601 acttagaact aaaacgacta aaatgtcatc taccacagaa gcacccaaaa ttgttgatcc
     3661 ttcttttgta ttcactacgt ttagttcttt taatacttct actgaaatac tgacagaagt
     3721 tgccgcaaga ataatcccaa agaaaatcgc ttcatttccc gaaacttgga atgctttgcc
     3781 tgtcaaccag ccaaaaacaa ccgggaagat gatcccaagc aaagcaacga acataccagg
     3841 tcggaaatat tttttcaaaa gagataaatc actttccaga ccagctaaaa acattaataa
     3901 gatcacacca atctccgaaa agtcatggac tagaatatca ggtttgaccc aattcaatcc
     3961 agcttggcct agcaaaacac caacaagtaa ttgtccaatc actgctggga tacctaatct
     4021 ccgcgagata tgtgagccaa tcgttgttga aatcaatatc aggcataaaa taccaataaa
     4081 ttccattctc atcattcctt tgtataaaat atagcccgaa cttagcataa catacattat
     4141 tgaaaaaata ggaaaatata ctcacaaaaa aaacaacaat ccaaaagatt tttttggatt
     4201 gttggttttt atacggtcta ttttaataac taaaaatgat taacgtatag tcatttttct
     4261 tattctgatg aaattgataa tctcctggat gcccatgaaa atcaaaataa agccgaatat
     4321 ttggaataga agcatcaaac ttttgaatgg attgaacaat aagacgaatc cgccaatcaa
     4381 caacagaata ctactataaa cactccaact tttagctttt gtattcatgc tgaagaacaa
     4441 ctggaacaag ctgttgatga taacagctaa tccaagaaga atcggcagga tagaaacgat
     4501 tgcaggtgca aaagcataga cgatcagagc taagatcagg aaaaaaagac cactgaacag
     4561 accgatactc caagaacctg ttttcctttt aaaacggtaa gcctcaaaaa gattcaacaa
     4621 cccaagcaaa acaagatagg cggtgatcag ataaccgata aaatgaaaaa cagcagaagg
     4681 gtttagcaca atcgcaatcc cagaaataat ataaacagca gctcttaata aggcgtattt
     4741 ttgaatattt tgtttaatcg tctcaaacat ataagaaaac ctcctttgac ttattttaac
     4801 gtgaactagt cattttacca aattaaatgt tacaaaatga gcgaaggaga agaatatctc
     4861 tggaaaaatc aacttctgag gatcttttcc atttttttgc cttttgctag ctcatcgatc
     4921 attttatcta aataacgaat ttctttcatc aagttatcct cgatgtcttc tactcgtaca
     4981 ccacaaacaa cacctgtaat caaggaacgt gaaggattgg ggacaggggc ttccgcaaaa
     5041 aattgttcga aagtcacttg tttttgtagt tgatattcta gttctgtttg ggaataaccc
     5101 gtcagccaac aaatgatttc atctacttcc tcttttatac gatcttttct ctccgctttt
     5161 gctacataca taggataaac gcttgcaaaa cttgtcgtaa aaatacgatt ttgcgccata
     5221 atcagtcacc tttctttttt tcaaattatt tactacttat agtatataag aaaaagagaa
     5281 gaaaaagcga ttattcaaaa aaacaaaaag gattgtgaca aaattcttgt caccatcctt
     5341 ttttccgctc tctgactttt tacaatcttc atagctcaag tgcgcatcag ataatcgaat
     5401 gctcctaaag ctgcagtagc tcctgaaccc attgaaacaa tgatttgttt gtatggacta
     5461 tctgtacaat caccagctgc gaaaacgccg gggatattcg ttgcgccatt tttctcggtc
     5521 actatttcat ttcttggatt catttcgatc gttccatcta gccaatccgt attagggagt
     5581 aagccgacta gaatgaatac tcctgaaaca gctagtgtat gcatctccat cgtacggcga
     5641 tcgatatagg agagagattc tacctgattc gtaccgctga tttctttcgt cgctgcatgt
     5701 ttgataacag tgacattcgc aagagagact agtttatcct gtaagatttg atctgctttt
     5761 aattctggta agaattctag aacatataca tgttttgcta acccagccaa atcgattgct
     5821 gcttcaacac cagaattacc accaccgata acagcaatct cttttccttt aaataaaggg
     5881 ccgtcacagt gtgggcaata agcaattcct ttatttttaa actctttttc gcctggtaca
     5941 ttgatagaac gccagtgcgc acctgtcgcg atgatggcgg tttttgcttt aagtgatata
     6001 ccgttagcta agccaatatt aataaaatgt tgctctttat ttaaggaaac ggcctgttga
     6061 ttcatcataa tgtcgatagg gtaactacgc acatgacttt ctacttgctg catcaatttt
     6121 ggaccttctg tgtaagaggt accaatcata ttttcaatcc ctagtgtttc aacgacttgt
     6181 ccgccgaaag aatcagcgac aagtcctgta cggattcctt tacgtgctgc atagatagct
     6241 gcactactag ctgctggtcc accgccaatt actaatacat cataaggttc tttttcaaac
     6301 aactcttctt caatcaaagg gccagtgatt ttttcaacaa tttgttcgat cgtcatgcgt
     6361 ccgctactaa attcttctcc atttaaaaac acagttggca ctgccatgat ttttttatca
     6421 tcgatttctt tttggaacat cccaccttca atcatcgtat gagtaatatt tggatttaat
     6481 acagctaata tattcaatgc ctgtacaacg tcggggcaat tatgacaagt caagctaaca
     6541 taactgtcaa aatgcaatgt ttgtgttatt tttttgattt taagactcaa agattcactg
     6601 attttcggtg cccgtccact aatttgtaac atagccagta aaaaagagga aaattcatga
     6661 ccgaggggga taccagcaaa aacgattcca ctttctttgc caactggatt gatagaaaaa
     6721 ctaggtgtgc gcatcgaatc tcttttttcc caagagattt taggagacat ttctgctatt
     6781 tccttcgtaa attcagctag tttttgacta ttttcactat tatccaaact aacagaaaaa
     6841 acaataggag attcaatcag tgctaaatat tgttcgagat tttgtttagt ttctttgtct
     6901 aacatatcca ccacctaaat ctttccaaca agatcaaaac ttggtttcaa tgtttcgcca
     6961 ctttctttcc attttgccgg acaaacttca cctgggtggg tacgtacata ttgagcagcg
     7021 cgaatcttat caatcagtgc actagcgtca cgaccgattc catctgcatt gatttccata
     7081 gcttgaacga ttccgtctgg atcaataata aatgttcctc gctgagctaa tccttgctct
     7141 tcatccaaaa catcaaaaat acgagaaatc tgatgagacg gatcaccgat catcacgtat
     7201 tcgattttac cgatagcatc tgatgtatca tgccatgctt tgtgagtaaa gtgggtatcg
     7261 gtagagcaag aaaagacttc aacacctaaa gatttcaatg tactgtattg ttcttgtaag
     7321 tcttctaatt cagtaggaca aacaaaagta aaatcagctg gatagaagca aagaatactc
     7381 cagttcccca taagatcttt ttcactgact tctaaaaatt ctccttgatg ataagcatgt
     7441 gcattaaatt cttcgatttt tttcccaatc aatgacatag taaaacctcc aataataatt
     7501 atttatttat aattattgta atttagttgg agttgcaaag tcaatggata ttttgttatt
     7561 taataaagat tactcaaaaa cgaaggttaa ttataaaaat agaagaggtc gcaagaaaat
     7621 gctactgctg gaaatactcg ggataacgtt gagtaacagt ttcctgttct ttcagcatca
     7681 tgtgtaagtg caatcccgtt tgaaatcgag cttcttctgg ttttttatca actaaagcct
     7741 tgagtaaatc ataatgttgt tccatgatcg tttcccatgg aagcccctga atggtcactc
     7801 gtaaccagcg gaaacgttct aaatgggtat tatggtcatc taaccagttc caaacttctt
     7861 ttcttcctgc aatttcgaaa caagcttcat gaaataaatt atctgcacgg aaaaaagcgc
     7921 gttcgtcatt tattttgact gctttttctt gttcttctaa aatcgtttct agcactattc
     7981 gtgtttgtgt gtccaatttg gaacaacatt caatcatgat ttgctcttcc aactgttctc
     8041 ggacaaagcg agcattttct gcagaaacaa gattaatttt ggaaacatac gtaccacttt
     8101 gaggtatcgt atacacgagt tcttgctgac gtagttgaat caatgcttcg cgaatgggag
     8161 tccggccgat agcaagatgt tcctccagtg ccttttcaga tattttcctt ccaggttcta
     8221 agtcagcata gataatttgt ttacgaatcg cttgataagc ttgtgattgc aagctgcttt
     8281 tcatctttat tcctccaaaa tcatttctat gaacgtagta taacagaaga ggtctgaaaa
     8341 acaatctggt atgtcacatt aactagtaaa tttgtataaa tagtaaaatt ttggttgaca
     8401 tagcgatttt tattgtataa aattcacttg aatacaaaaa ctaatatgtt agtttaggag
     8461 gggaaaaatg attgatttaa acaactggag gaactttatc cctgaattat ctcaaaaaga
     8521 agtagaaata cctcattttg accgtgcatc attaagagaa aatggacaaa aaaatcctgt
     8581 ctggatccat ttcggtggcg gaaatcttta tcgaggattt catgcagaaa tcgctcaacg
     8641 tttagcggat ctaggcgaat tgtccactgg tgtcattgtt tgtgaaacat tcgatgaaga
     8701 aataattgaa agggcttacc aagattttga tgatttgatt cttgaagtgg tcatgccaag
     8761 cagtggagag ttcgtcaaac gtatattagc tgcgacagct gacagtctgt attgtcatcc
     8821 agattgttct gaacactttg ataagatgat tcgacacttt gaaaatccta gtttacaatt
     8881 agttactttt gctattactg aaaaaggtta tcgattgaaa gatacaaata ataaatatat
     8941 aggaccgatt gcagtcgata taaaaaatgg tccaaagaag ccatcacata caatgagtat
     9001 tcttgctgcg ctactttata aacgtttttt atctggagct tggccgattg cacttgtctc
     9061 tacagataat ttttcacaaa acggtagtca attacgtact tctttgctaa cgatcgcaaa
     9121 agaatggcaa aaggaaggtt atgtacaaaa tacatttatc caatacttat cgaatgaaga
     9181 aattgttgcg tttccatgga cgatgattga tcgtatcacc ccgaatcctt ccttgtcagt
     9241 tagcaaaatg ttggcaaaag agggcttttc aaatatgtcg attttccaaa ccgcaaaagg
     9301 aaataatatt gctccatttg tcaatacaga ggacatccat tatttaatca tggaagatca
     9361 ttttcccaat ggacgtccga aattcgaaaa agctggggta ttcttgactg atcgtgcaac
     9421 ggtagataaa gcagatacga tgaaggtgac gacttgcctt aatcctttgc atacgtcttt
     9481 agctattatg ggttgtttac tggggtatag gagcatagct gaggagatga aagatccaga
     9541 tttatcgctg ctagtttctg aaatcgggta caatgaaggc ctcccagttg tggagtctcc
     9601 aggtatcatt gatccaaaga tctttctgga agaagtaatt actgtgcgct tttctaatcc
     9661 aaatattcct gatatgcctc agcgaatcgc cacggatacc tctcaaaagg tggcgattcg
     9721 ttatggtgag acgattaaaa aatatatgga aatagaagtt aaagacccgc agacacttgt
     9781 attcatacca ttgactctcg ctgcttggct tcgatacctt attggcattg atgatcaagg
     9841 aaaaccattc atcccgagtc cagacccact attgacagac tttcagcata agctttccga
     9901 tattcaactg ggtacgcaag atacatcaca tattcatgag aaaatggctc ctattttgtc
     9961 aaataaagaa atttttggtg tagatcttta ccaagcagag cttggcagaa aaatagaaga
    10021 aatgttcatc aagatggtag caggaccgaa tgccgtacga aaaacattac aggattactt
    10081 acaagaacat ggaggaaatt tatcatggaa atgactttta gatggtacgg atcacaggaa
    10141 gaaaagatta ccttagatga aatcagacag attcctgcgg tcaaagggat tgtaggcaca
    10201 ttgatggata taccagtagg agaggtatgg cccagggaga ggatcaaaga actaaaagaa
    10261 gaaattgagt ctcgtgggtt aacactaaaa gtaattgaaa gcgtcaatgt gcatgatgcc
    10321 attaaaattg gattaccttc ccgtgagcag tatatcgaaa actataagca gacaatccga
    10381 aacttggcag aatatggaat agaagtcatc tgctataatt ttatgcctgt atttgactgg
    10441 gtgaaatctg accttgacta ccgcttagaa gacggctcat ccacgttagc ttttatatct
    10501 gatgatattc cagatgatcc aagagaaatc gtcgcgcgca tcgaacattc cagcaatgaa
    10561 tttgaattgc cgggatggga acctgagcgc ttagctcata tcaaatcctt gcttgaagcc
    10621 tatgcatcag tagacgaaga aaaacttcga gaaaattttg cctattttct ccaatcaatc
    10681 atcccaacat gtgaagaggt aggggtcaaa atggctgtac atccagatga tccgccatac
    10741 tcgatttttg gattacctcg aatcgtaaag aatcgagaag atttagattg gttgtgccgc
    10801 atagtagaca gcccttataa cggaatcact ctttgtacag ggagtattgc agaagatcca
    10861 gaaaatgatg tatatgggat tttagcagaa ttttgtcaaa gagatcgaat cccatttgca
    10921 catgttcgaa atattaaatt tttagctaat cgagatttct atgaggcacc gcataaatcc
    10981 gaatacggtt cattagacat gtaccgcata ctaaaaacaa tgtatgacaa cggatttaac
    11041 gaatacatcc gtcctgatca tggaagaatg atctggaatg agacaggaag accaggatac
    11101 ggcttatatg atcgagcatt aggtgctgtt tatctaaatg gattatggga agcaatcgaa
    11161 aaaggaaaca aaagtaaaga taattagtga aaaaaactgt aattttatta tgtaaataag
    11221 aaggatgttc aaattcttga tacataaatc cggaggttgt taataagcat tcggatttat
    11281 gtatcttatt tggtctagga agtaacttga ttttcttttt tcgattgatc catgagtgct
    11341 tcttctttta attcaaagat atattctgag atcctcataa tcactttttt ccagtcttct
    11401 ggtgtgatga ttccttttaa aatatagatt tttttgatat gagaaggcaa ttgtttcaaa
    11461 gggcagtcgc tgataacgat gttgcagttc tccataaaat cattttgtat tttgatcgat
    11521 tcatttgaaa aaatttgttc tatcttaacg atcagatctt tactgatata aaaatcacgc
    11581 gtatagttca caccaatcac aattcgcggc tgttttttgt agcgatcata caaatgtact
    11641 aggtcttcaa ccatccattg cacattttcc ttttctaaaa taactggtaa caagtgttga
    11701 ttttgttctc tgaaatccat ataaaattgt tcaatggcgg tttggacttc tttcaacacg
    11761 ctatgttctt gataaagcat gaaagtagga aggggcgtat ttggttgatt gaagttaaga
    11821 aatccattat aaagtttatt tcgtgcgaat gccaatgagt aaagaatctt ttctttttca
    11881 ggtataaaca aatcaaatac agtacaaaag gactccacca tttctcttga ataaagaaca
    11941 tgaggaacgt ttgctttttt taaaagtttg tattgctcca agcttgtttc ttccgattcg
    12001 attttcgtga tagaaagtcg agctaaaata ttcactaaga tgcgttgttc gcgacaaatt
    12061 ggcagattag gtcgcaaaat atctacagag ggatcaataa aaaagtcaat atattcatac
    12121 tctgtgaatt ctttttgtac gtctttcaca gaagttgcag gaaaattctc tttacatatt
    12181 tttaatagaa aatataattt atctatcata ccgctattta gtcggtcaag tacttctttt
    12241 ttaaaaaaag tattcatcat aaaagccact acttgcggat cttcatcata aaattctgta
    12301 gcagtacttg aaaagatgtt ccaataaata tctaatgctg catattgaat ttgtacctct
    12361 tttccagaaa aagactttct gccattatta gaaaaggaga tagacaaacc gtacaatgct
    12421 aaaaatgcat taatcttttt cattttcgta tacaaataag aggcactata gtttgtttgc
    12481 tgacttaaac tgataatcga atttgtctga cagctgaaca aagaagtcaa gatctgataa
    12541 ctgactgatt cgttgcagta tcttccaaat agacgataat agcagtaagc cggatcaatt
    12601 ccttcaaaat tcaactttaa aaaaggtttt tgcttatcaa tatgcagttc tgttagattg
    12661 agacgctcaa agtcttgttc taattctttg atgtatagta aaaaatttga ttcagacata
    12721 tggaaatgat ctgctaaata ttgtgtagta ataaagaaac gatgttcaga taggaaaaga
    12781 aaaatatcta attttgtatt gctttttttc ttcaagagaa acgttttaat cgcttcttga
    12841 gtttgcatga aagaggctcc tttttactta aattgttaaa acttgaaaat attactgttt
    12901 ttttcataaa tttagacaaa aaaacagtaa acatataggt agaatctcta ctatcttatt
    12961 tcttgcatac aaaaaaatca aggagtgaga gagttatgag atattcaacc atcttaatat
    13021 caacatttgc agccttaagc ttatcgctta ctataaatca gacagtccac acagaggaga
    13081 tagaaacagc caaatggaca gaaaccaagt gggccaacgt caatcgaatt acctttcagg
    13141 atgaattttc atccttcaat tcaggagtcg caaaattaag aaaaggacaa acagcgacca
    13201 tcaaagcaaa aattgactat tcaggagact tagcacctat actacaatca gctgttacat
    13261 ttgagaatgt tgatcccgct ttgtcgattg gctatgacga gaacactttg actatccaac
    13321 acaagcaagc gatatttacc ttcaccgtta cattaaatca ggacttgtta aaaccagcgc
    13381 tttttactgt caaggtatca gatggactac cgaacgatca tcatcattta acgccgtata
    13441 gtcagcggca gacaattgag caagattcag ctatcgactc aggaggagat cttgttgaag
    13501 aaccaacaga taaaccagaa aatgaaaata agccagaagt accgcctaca gaaaatccag
    13561 acggagaaca gaaaccggaa atagaacctg gagaagaacc cgatacagaa actcaaccag
    13621 agccagacaa tgaatcaaaa cctgaaataa cccctggaga aaaaccagat gtagacccag
    13681 aagaaaaacc agatgtgact ccagaaccag atacggattc tggaaaccaa acagtaccgg
    13741 aaacaaatcc agacacagat aatgaaactg aaaatccaga aaaaccagag gtagccccag
    13801 aagaaaaacc agatgtaact ccagaaccag atacggattc tggaaaccaa acagtaccgg
    13861 aaacaaatcc agacacagat aatgaaactg aaaatccaga aaaaccagag gtagatccag
    13921 aagaaaaacc agatgtgact ccagaaccag atacggacgc aagagaccaa ggaataccag
    13981 aaaaaataaa caaaaaaaca attcaagagg atggaaaaaa agagagtaaa aaatcaaatc
    14041 tagcaattct aaaaataaat gaagagcagc tgaataaaaa atcacgaata tttgatagcg
    14101 cccaatcagc tgaaacctta aaaagtagca aggatacaac ctttgctgtc ctgaaacgaa
    14161 aaataaacag ctaccaaaat ccggagagtc acaaaacaaa gttatactgt ggagcggaat
    14221 cattctatta agtatagcaa caatgctttc tgcaaaaaga tttaaacaaa acagatctct
    14281 ctaacatttg aataatgtct gtgaacgcat ttttcaaata aaaagaaata tccagaaaat
    14341 gaccccaaaa taccagattg aaatctgata tttggggtcg ttcatacttt atctttcttc
    14401 atatttattt taagggatat ctgtttcttt tggaagatgg ttcgggatct ttttcacttt
    14461 caatacatct aaaaagaagg taaagatcgg aatgccgaca atcaagcccc aaacgccaaa
    14521 gaaccgttcg ctaacaagta agaccacaaa tgtataaaaa atcggcagtt ctgttttgct
    14581 ggacatcaac ttcggattca gcacataaga ctcaattaga tggacaatca aaatcgtaat
    14641 caggatataa acaacatctc ggatgcctcc ttgggaataa gctatgaaag atagaggaat
    14701 acaagaaatg ataacacctg ctactgggat cagacttaaa atgaaaatca tgatcgctaa
    14761 actcagcagc tgatgaaagc caaatacagc caaggcgatt gtagtgagca acgtatttaa
    14821 aagagcgaca acaaattgag cttctaatac caaaccaaat gtattgacaa acttatcggc
    14881 aaaatagtaa atatcttgaa agaaccaaga aaattcactt tttaaaaaca atcttgagaa
    14941 tacaattgtt tttttctttt caatcataaa aaagaaactt aagatgaatg acatagcaaa
    15001 cgccactgcc atttttccta tatcctgtaa atagccaagc gcaatcgaag cgccattttg
    15061 aagctgttca aaaaaatcgt ttcgctcaat ataagtatgg atatattgta aaacaggatc
    15121 tgcatctttt ggctgatgct cgtaaaaatt aataacggac tggatcatgt caaatgtttg
    15181 atgaataagc atcgggatat actttgtgaa tgccagatag ataaggtaaa cgatcagtgt
    15241 ataaatcatg atagctaaaa cacctgtagg gattcggaca aatcgctgaa tgatttgaac
    15301 aagatgaatc atcaaataag taaagataaa tgtgagcaaa atggttgtaa tcatacttct
    15361 aactaagaaa agaacaaaaa cgacaaataa taaaacagtg agacggcgta ttttttcatt
    15421 cgccaaaaaa cgctgataaa cggtcaaatc gacaacctcc aaataacaaa aaataaacac
    15481 gttattcatt atatgatgga atatgaaaat aagaaagagc aaaaagaaaa accgctaaat
    15541 gacgttatct tatgagttgg ttttcctcat aaaatcgttc atctagcagt ttcagccctt
    15601 tttctggtct tgatgaaaat tatctagcat ttttcgggtc agatgttgca gtgtatccaa
    15661 ttcttcctgt tcaagtggaa gataagactt gatcttttgt ggaatacctt ctgcttgttt
    15721 ttgcaacgca gcaccttgag cagtcagcgt aacatttacg attctttcat cacccgtttc
    15781 acgctgacga ttaatataat ttttttctgc taactttttt agtaagggag tcagcgtacc
    15841 agaatccaga cacaaatcat ttcctagctc tttcactgaa gtctttttct tttcccataa
    15901 aactaacatc acaagatact gggtataggt aagattcagc ggcttgagga ggggagtgta
    15961 gtgtctaatg atttctttag aggcggcata taaaggaaaa catacttgat taactaaata
    16021 tagatcttcc atttttccac ctccgctgtt ttactatagt gtatcatagc ggatttacac
    16081 aaaaaagtct attcactaac tgctttcaga gtaacttcta tatttccagc tgtagctttt
    16141 gaatacggac acactttatg cgctgcctct aataattctt gcgtttcttc cagagaaaga
    16201 ccttcgatag atccttcaat ctctacacct aagacaaagc tcgtttcact ttctgaataa
    16261 agggaaactt gtgcactgac agtagaagcc ccagagatat ttttttgctg tttgatcaat
    16321 tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa acaattgttc agggttggtt
    16381 gcattttcga cgcgtttacc aggagctgca atattcaatt cgaatgtacg atcgggatta
    16441 tgcacttctc cagagcgtcc gcctgtgttg atcattttcg tagaatacat ttttttcata
    16501 aaattaccac ctttaattat attttataca attgaatttt acacaatata attgtggaaa
    16561 gcaaagaaat ggattggcat aagataaata agagaaagca catgaaacag acgcgctttc
    16621 tcgaatagca aacatataca aaaaatatca gagacaaaaa ataatctcat cataaacatt
    16681 acatatattt ctcaaaaagt tgttttcttt cttcaaaaat tacttcacga tggacctgat
    16741 gaagcatcca taaataacca aaaggatctc tgaacattga gttagtcaca ccaaagtcca
    16801 tcatttctgt catttcttga atctctacac agccatttcg taatgcttta ttatgtgtgt
    16861 cctcgatatc agagacgatg atattgaacc agatcgtatt tggatgttca gcagtaggag
    16921 cagtcaaacc aagagacgtg ttttcatcca gcatatggaa tctcgtacca tacaaggtaa
    16981 aaatgacttc attattgcct ctagggtaat ctgttgcctc aatcagttgt atttcatcaa
    17041 agattgtttg atacagttct agtgctttca aactatcatt taatacaaaa tcgatttccg
    17101 ttcctttatg cataaagatc tcctctcctt ttcagtcgaa cagttactag attcttttat
    17161 tataccagct aaagaaaacg cattcaaaaa aatagcggat ttacttacca actcattcga
    17221 ttggatgata agtaaatccg cgtcccatta cttctgctac gctgctgaca atgacaaagg
    17281 cacttggatc gatttcttct atcaatggtt tcattcggga aaattcatga tcagtcacaa
    17341 cgatcaataa aacctctttt gactttcgat tatacccgcc ttttgcctct agcagggtaa
    17401 ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc ttccaaataa tgttcactca
    17461 tgaccataac agatttcttt cgattgatac ctgtttcgat ataagtcatg acaattgaag
    17521 tgattgcaat agataaaata gcataaagaa actcttctat tccaaaaata aacagattaa
    17581 gagaaacaac gaatgcgtct gtaaaaaata agccaatcga agtattcaag tggaaatatt
    17641 ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga agagttgttt ttatataaaa
    17701 tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac agacaacaac cgatctgaag
    17761 taatcattgt ttctggaact attgcaatga ttaaaggaaa aaccaagctt ccgaaaagta
    17821 ctttaaaaaa gggtttttta cctaaaaata gaagagctag taccaacata acgatattca
    17881 acactaaaat aactatagct cggtcaaagc ctaaagcagc ttccagtaat attcctagac
    17941 cgctgacacc tccagcagca atatgatgag gccctaaaaa catattgata gcgactccta
    18001 atatgaagag ggcaaaaata atcttaatgt atgtccatat aaattgtctc gtttctttca
    18061 tttattcact tccttaattc attaataata ctcttatctt attataactt acttttcacc
    18121 ttaagttaac tttaattaat aaaaaaatta ggctagtcta aattattatg tttcattctt
    18181 ctagaatata cttctacgcc aaaaactgtt aaaaaacttt tactttagaa aattggagaa
    18241 attgatcgct taagataaat tcaggacact aaatagtaca ggaagtagac taaaactttt
    18301 aaaagtttta agtctatcta tttggcaagt ttaaaaaata aaaattcggt atcaaaaaac
    18361 tgttaccgat aacatttttg aaagcgttgt cttttgcttc tctatcactt atagtgatga
    18421 cgtcatatta aaacacaagg aggaaatcaa tggatacagc tgcaatttat catcgaccgg
    18481 aaagtgaata tgcatttcta tatacgaata caagatttcg tattcggctt cgtactagga
    18541 aaaatgatat caaaaaagta tatgtgctat gtggagatcc atataccata acaactgaaa
    18601 aatggtatca aaaacaacga ccaatgaaaa aatgtctaag taccaatgtt catgattatt
    18661 gggaaattga agtgacgagc gaaacaagtc gcttacagta tgcgttccat gttgttgggg
    18721 aagataacac ggactgtttt tacggtgatc aaggaatttt tccttatcga gaaaatgtga
    18781 ttactgaacc aaatttttat tttcgaatac cttattttca tcaaatcgat cgattcacta
    18841 ttccagaatg ggtaaaagaa acagtatggt atcaaatttt tcccgaaaga tttgcaaacg
    18901 gggacaaagc aaatgacccc gaacacactt taccttgggg aagtaaagat ccagaccgag
    18961 aagacttttt cgggggagat ttgcaaggtg tgatggatca tttggattac ttgacggacc
    19021 ttggcatcaa tggcatctat ttttgtccca tatttaaagc cacatccaat cataaatacg
    19081 atacgattga ttattatgag gtggatcccg cttttggcga taaaaaactt ttaaaaaact
    19141 tgattgatga agcacataaa agagggatac gtatcatgtt cgatgctgta ttcaatcata
    19201 tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa cggagaaaaa tcgatctata
    19261 aagactggtt ccacatccgt tttttcccag tagattctta tcagatgact gacttaccag
    19321 aaactgctga aaatatccca tatgatactt ttgcttttac tccattcatg ccgaaactaa
    19381 atacagcaaa tccagaagtg caaaaatatt tgctggatat cgcaacttat tggataaaag
    19441 aattcgatat tgatggatgg cgtcttgatg ttgctaatga agtcgatcat catttttgga
    19501 aaaaattcag agaagcagtt acagaaatca aaccagacat ctatatcctt ggagagattt
    19561 ggcattcctc tcaagcttgg ctgcaagggg atgaattcca tgcagtgatg aattatgcat
    19621 ttacagattc gattaaagat tattttgcaa aaaagaaaat cacagcttca caaatggtca
    19681 gtggaatgaa tcatcagcaa atgctttaca gagatcaggt gaacgaagga acattcaact
    19741 tattagattc tcatgatact gccaggatct tgaccctttg ccaaggtaac aaagaattga
    19801 tgaagtctgt gatggccttt atgtttcttc aaaaagggtc tccttgtatc tattacggga
    19861 cagaaatagg gatgactggt gaagatgacc cggattgccg caaatgtatg atatgggaga
    19921 aggaggaaca agatctagag ctattcggtt ttataaaaga acttgtttct ctaaggaaac
    19981 agttgtctaa gattatttct gaaggttcta ctcagtggct aatagtaaat gatcgtgaag
    20041 ataagctcta tttcacacgg aaactagagg gacagatcat ctatgtttac tttaatcagt
    20101 caaaagaacc ttgggtagta gaacaggaaa atgaggtgat tcttagtcaa aattgtcagt
    20161 tgttagaaga cgggaaagca gagatacgac aatacggatt tttgatcatg tgttgaaaac
    20221 tgttaccggt aacaacaaga aagcgtttgc aaatgaagat ttgtgcccat tataataagg
    20281 gtgtaacagc acgttgaata caaaggagga aatgaagatg aaaaaaagaa gtgtgaaaca
    20341 gttgggttta gggttaatct ctttaggaat cttaggcgga ttagcggctt gtggcaatgg
    20401 taactcttca gcagaagggg aagccgatga aggaaaaacg ttaacagttt ccgttgattc
    20461 tggatataaa gattatataa acgaaataaa aaacactttc gaaaaagaaa acgatgtgaa
    20521 aatcaagcta gtagaaaagg acatgttcga tcagttggaa tcattagcgt tagatgggcc
    20581 tgctggaaag ggacctgacg ttatgatggc agcatatgac cggatcggtg cgttaggaca
    20641 gcaaggacat ctggcggaag taaaactggg aaatgaagca gcttacgatg aaacagacaa
    20701 agcccaagtg acttatgatg gaaaaatcta cggagaacct gcagtaatcg agacccttgt
    20761 tttgtactat aacaaagatt tagtcgatac agcaccatca acgtttaaag atttggagaa
    20821 tctatccaaa gacagtcgtt ttgcttttga gtcagaagca ggaaaaaata caggattttt
    20881 agctaaatgg actgactttt attattccta tggtttaatt gcaggttacg gtggctatgt
    20941 atttggtgat gatggcacaa atccttcaga tatcggtttg aataatgcag gtgctgtaga
    21001 aggaatctct tatgcaacag attggttcaa aaatgtttgg ccaaagggaa tgcaagacat
    21061 aaaaagtgca ggagacttcg ccagccagca attcatgtcc aataaaactg cagcaatcat
    21121 tgacggtcca tggcaagcgc aaacatacaa agaaaacaat atcaattatg gtgtagccaa
    21181 aattcctact ctaaataatg gacagcctta tcaaccgttt ggcggaggaa aaggatgggt
    21241 agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa tggcttgatt atgtaacgaa
    21301 tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa atccctgcaa accaacaagc
    21361 tagggaaaca gcaaaggcta aaaacgatga attaacaaca gctgtgattg aacaatatga
    21421 aacagctcaa gcgatgccaa acatcccaga aatgggcgaa gtttggacag gtgcagaaaa
    21481 cttgatgttc gatgcagcat caggttcaaa aacaccaaaa gaatccgcag atgaagcagt
    21541 aaaaacaatc agtgaagcca tagaacaaaa atactgatta aaatgataac cgtccatttt
    21601 tataaaaaat ggaacaggtg cttcagataa aagtggcaag agcgagatgg aaaattatct
    21661 tgctcttgtt gccattatct taaaagcagt ttgcggttta gcaagtttag agggggcatt
    21721 cagatgcagc aagataaaac aagcaatatc aacgaaaaaa aaatcacgct ttgttcactt
    21781 attccaggga tggggcagtt tgtaaatggc caagctttta aaggtatcgt ttttttcgcc
    21841 atattcgtcc tattcattgg tcagatgctt ctgggcggat ttcatgcatt ggtaggattg
    21901 gttactttgg gaagtatacc aatggaagat cattcattat ttattttgat tgaaggcact
    21961 ttgcaattca tcattacaat cattttcttg attttttacg gtttgaatct tttagacgct
    22021 tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca atcggacgat gaaggaagtc
    22081 atacataata taggtgatga aggttttcct tatctattga cacttcccgc ttatcttctc
    22141 atgattttta cgatcatttt cccagtccta gttacattgt tcactgcatt tactaattat
    22201 gacttcaatc atattccacc agccagttta attgattggg taggggctaa aaactttttt
    22261 agtatcttct ttttaagctc atatcgtaat actttttttg cagtcttttc gtggaccgtg
    22321 atttggactt tatgtgcaac aactttgcaa atcacccttg gtattctcac agcggttgtt
    22381 gctcaccaga aatttattaa attcaaacgt attttcggta tcattttctt attaccatgg
    22441 gcggtcccag cttttattac tatcatgagt ttttcgaata tattcaacga tagcgtaggt
    22501 gccatcaata ctcaagtgat tcctttcata aaccagcttc cttttgtaga tatcagtgca
    22561 atctcttgga aaacggaccc gaactggacg aaagtagcaa ttatcttagt gcagggctgg
    22621 ttaggatttc cctatatcta tgtgatggtt acaggaatct tacaatcgat ttcagaagac
    22681 ttatatgaag cagcaaaaat cgacggagca aatgcatggc agcgcttttc aaacatcacg
    22741 cttcctgctg tcttcctagt ggcagcgcca acatttatta cacagtatac ggggaatttc
    22801 aataatttct ccatgatcta tctgtttaac aatggcggtc ccggaagcgt aggcggagga
    22861 gctggttcta ctgatattct tatttcctgg atctataaac ttacgactgg aacttctccg
    22921 cagtattcta tggcttcagc aatcacgttg attatctccg tcatcgttat ctgtgtgtca
    22981 ttgctggtat ttaaaaagac aaatgcgttc aatatggggg attaacaatg aaaaaatttc
    23041 attcgagtgc tcgattccaa aaacgacttt ctcacttttt tacttacttt tttcttttaa
    23101 tactgtcagt cattatcatc tatccgcttt tgatcacagc aagtactgcc ttcaagtcag
    23161 gaaatattgc agcttttagt ttagatcttt caagtgactg gactttagga aactttactc
    23221 ggctattcag tgaaacactt tacgggactt ggtataaaaa tacattgatc atttctgtcc
    23281 taacaatgat cgtacaagtg actgtagtaa ctttggcggg ctatacttat agtcgctatc
    23341 gttttatcgg ccgcaaatca agtttgatgt tctttttagt gattcagatg gtaccgacta
    23401 tggcagcatt gactgccttt tatgtcatgg ctttcttatt agaagcgctc gataagtact
    23461 ggttcttgac aatgatctat ataggcggtg gaattccaat gaatacttgg ctgatgaaag
    23521 gatactttga cactgtacca atagatttag atgaatctgc taaacttgat ggggcagggc
    23581 atttcaggat ttttttccag attgtattac cgcttgtcaa accgatgctc gccgttcaag
    23641 cattatgggc ttttatggga ccttttgggg atttcatgtt agctaagttc ctgcttcgaa
    23701 cacctgaaaa tcagactgtt gctgtcggct tacaaacatt tatttctgat gtgacaaacc
    23761 aaagagtctc tctttttgct gctggggcaa ttttgattgc actaccgatt tgtctattat
    23821 tcttcttttt acaaaagaac tttgttaccg gcctgacatc tggcggaaca aaaggatagg
    23881 agcagagtat catgcaaaca tttccgttaa actatttttc cgcattacgt acgccaactc
    23941 aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt tttcttgata tttgtatttt
    24001 tagtttcctt gatggtcatg cctgtgactc ttttttatgc caatcagatc caagcgattc
    24061 cattagaaca atttctatcc gttcattcgc tgatcgatga acaaggaacc caaaaatttt
    24121 ctgaacttga attatctgaa actgggttac aagcatcgca acaaacgata gctgtgaccc
    24181 ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca atccgatcat ggaactttta
    24241 ttgattttga gaaggaacaa tgggtgatcc aacaaaagga taaatctggt atacgccgct
    24301 atacgatgaa ttatagccca tctttccaac cagattctgt acgtacgccc gaagatttcc
    24361 aacgattttt agaaagagaa ttttatgcca gtaatcgtcc aacaatcatt ttatcttata
    24421 gtttaagtct tggtcttgtc ctatttgtca tgacgagtct cattttattc ggggcttcct
    24481 ttttcttgtg gatgacaaga aaaagccaac tttcatccat tcatacattc aaagagagtg
    24541 caaatttgat gctgaatgtt atgggaatag gttccatggc agcagcagtt gtagggttta
    24601 tccactttga ctttatcttg atgctaagtg tccaaacaac gataactgtc ttgctgcttt
    24661 tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt cgaatgacaa gtttaagcga
    24721 tttatgcgac aatgaatgtg aaaaaaatga aaaataaagt agtttttgaa aaatttctga
    24781 aaaaattaaa cttcttagtt gattcttttc ttttttagta ttaacgtaat agggtagttt
    24841 ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa tcaattattt tcacgttctt
    24901 tctcgctccc tgtcgaagta aattattggg acggtacaac gaaacaatac ggagatacgg
    24961 acactcctcc ccaaatcaaa atcaatatcc atgaagaaat cccaatgaaa gagattacaa
    25021 gtaacgcttc tttggcacta ggagaagcct atatggatca tcgaatcgag atcgagggaa
    25081 gtatccaagc attgatcaac gatgcttatc agcaagcaaa cagcttttta cgaggaaaag
    25141 attatctaaa atggctgcca aagaaagaaa aacatacgaa acaaaaaaac aaagaagata
    25201 tccatgcgca ttatgactta ggtaacgact tttataaact ttggctagat ccaactttga
    25261 cttattcttg tgcttatttc aatacacctg aagatacgtt ggaacaagca caaatcaata
    25321 aagtccatca tatcttagac aaactcttta tcaaagaagg cgaaacgttg cttgatatcg
    25381 gttgtggctg gggaacattg atgttcactg ctaccaaaga gtataatgtc aaggcaactg
    25441 ggatcacact aagtgaagaa caatacgatt tgattaccaa aagaataaaa gaagaacatt
    25501 tagaagataa atgccgtgta ttattaatgg attaccgcga actaaaaggc gaaacgtttg
    25561 atcatatcac aagtgtaggt atgttcgaac atgtaggttc tgaaaatctt gaaggttatt
    25621 tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc tttgatccat ggaatcagcc
    25681 gacaacaagg cggtgcgaca aatgcttgga tcaataaata tattttccct ggcggttatg
    25741 tccctggtgt tactgaatta gttgataata ttacaaaaaa cgatttgcaa ctgattgatt
    25801 tggaaagctt acgtcgtgac taccaattga cattagaaca ttggacaaag aattttcatc
    25861 aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt ctatcgaatg tgggatctat
    25921 atttacaagc ttgtgcagct tcatttgaat caagtaatat cgatgtgatt caatatttgc
    25981 ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc ataattgagg caaaagtact
    26041 gtttaaagac tatttaaaaa gaagctaagt tttatgatgc tccagaagtg aacttttttg
    26101 tctaacttct aggattgtct ctaaagctta gtttcttttt ctttatattt tcataataaa
    26161 agtttggttc tttaattttt aaacatgaca gaaaattttt tcttcgttat acttgtaata
    26221 gaatactatt ttataacaaa ggggatcgaa tcaatgaaaa aaactgttat ttatactagt
    26281 ttatttgcag ctttgttttt agctgcttgt caatcaaata ccaatcaagg cacatctggg
    26341 aatacgtctt ccagtagcga acagcgctct tcacaggtat cggactcctc aacaaaagca
    26401 agcacatctt cgtctagcca gacaaaaagt tctagtgaag caagtactca gtcagatatc
    26461 aaagtgtctg cagctcgtgc gatcgaattg ttccaagata aatacccaga tactgcaatt
    26521 actagtttgg aattagatag tgattgggga tcttacttct acaagataga aggtgtcgat
    26581 gatcaaaaag aatacgaagc aagaattgat gctcaaaatg aaaaaatgga gacagagaat
    26641 ccagaaactc tagatcgaga tgaacaaaat ggtcaaaaga aaaaagaaga tggtctggat
    26701 gttgataaat tgatcacgat tgaggaagca gcaaaaatcg ccgtcgacaa agtaggaagc
    26761 ggtacggcaa cagattggga tttggataaa gatttaggta ctacttattg ggaagtcaaa
    26821 gtaaaagacg gcaatcaaag tacatcagtc aagatcaata gccaaacagg cgaagtactg
    26881 tcaactgaac aagatgatta agaatttctt cggaaaacaa gagttgattt ttcttttagt
    26941 catgatacac tagacaaaat aacttgtttg aaggagcgat ttacttgagt ttagaaacga
    27001 cctttgccaa tcatatcttt gccaatcctt tgatgaatgc atctggtgtc cactgcatga
    27061 ctacccagga attagatgaa ctggctcatt cagaagcagg agcatttatc actaagagct
    27121 gtacgatcaa tgaacgaaaa ggaaatcccg aaccacgcta ttttgatgtt cctttaggga
    27181 gtatcaattc tatgggactt ccaaacttag gtttttctta ttatctagag tatgctcttg
    27241 cgtatgaaaa agtgcaggaa aaccaaaatc aaccgttatt tttttccatt gccgggatga
    27301 gtgtccagga aaacttggaa atgcttgaga aaatagaaaa aagtgggttt aatgggatca
    27361 ctgaattaaa tttatcttgt cccaatgtgc ctggaaaacc acaactagct tacgattttg
    27421 aggccactta tgaaacactg aaagaagtat tcagcatctt ttctaagccg ctaggaatca
    27481 aattgcctcc ttattttgat tttgctcatt ttgatcagat ggctgatatc ttgaatcagt
    27541 ttccattgac ctatgtcaat gctatcaaca gtgtgggcaa tggtttgtat atcgatacag
    27601 aacaagaagc agtagtcatc aaaccaaaag aagggttcgg cggcattggc ggagagtata
    27661 tcaagccgac tgctttggcg aatgttcgcg ctttttatac acgtttgaaa ccagaaatcc
    27721 aaatcattgg tacaggtggg attcggacag gacaagatgc atttgaacat ctgctatgtg
    27781 gcgcaagcat gttacagatt ggtaccgagc ttcataaaga agggccggaa attttttcta
    27841 gaatcataaa agaattaacg cagattatgt cagaaaaagg atatacgtca attgacgaat
    27901 ttaaaggcaa attacgcacc atttcatagc aaagagacga aggtcatgat tgatcttcgt
    27961 ctttttttat aaaaaacact cgtctgttca ttcctgtgca agcgtactca ttgtatgtta
    28021 gacgaacttg tgggaaaata acagaggcaa aaaggaggat aatatgaatg atgcaacaga
    28081 attagcaaaa gagcttaaag aaaaagaatt tagttttcaa gaactagtta cggatataca
    28141 gaaagaaata aagaagcaaa atcatgaatt gaatgcgttt gtcgcgcttg aaccattcga
    28201 gagtaattcc cacgagctat tgattcccca gtcagaaaaa gggccattgg ctggtatccc
    28261 atttccttta aaaatgctcg gtcaagaaaa aaagggatgg ctagctactt caggatctcg
    28321 tttatttgaa acacaccgag cttctcatac atctaattat gtgcggcaag cagaagcgat
    28381 aggtctagtt ccttttggac aaaccaatgc gccagagttt ggtttcaaaa atattacaga
    28441 cccagtcatc tatggcccag caagaaaccc ttggaacctt gaatgtacac cgggcggatc
    28501 aagtggagga gctgctgctg cagtttcatc aggaatcgtt cctttagctg gtgctagtga
    28561 tggcggtggt tctattagaa tacccgcttc gttttgcgga ttgattgggc tgaaaccttc
    28621 gcgagggacg atgccagttg gtccatatgc ttggagagga tggcaaggag ctgctattga
    28681 tttcggcttg acagtttcta tgagagacac ggaggcttta ttttatggga tgagaagtat
    28741 ccattccggt gcgccatatc aagtatcgcc agttgagtgg caaacacatc caagaaaaaa
    28801 acggttgaag atagcttttt gtgttgattc accgatccac tcacagatta gtgaagaggc
    28861 agtacttgct gtaaaaaaag ctgtagattt ccttggaaaa gaagggcatg atttgacaga
    28921 gattccttac ccactagatg gtcgtaaact gatcacgtct tattatcaga tgaatggcgc
    28981 agaaacagca gcaatgatcc gctcgattga aacaggcatc cagcgagctg tcagaaaaga
    29041 agaacttgaa cccatttctt ggactttgtt ccaatatggt cagaagctct ctgccgctac
    29101 ttacatcgat tctctgcatg tatgggatga agcagcaatt gtcatggaaa acctacatca
    29161 agaatacgat ctattccttt caccaacgac tgcatttacc gcccctaaaa tcagcgaaga
    29221 tttgcaaagt gatgcgataa gagcacagat ggaacacatc agtgattgtt ctgaagtaga
    29281 aggtttagac gttgtttctt ccatgtttga ggagagcttg aagatcacac cttatacaca
    29341 gttggctaat ctgactggac aaccagcaat cagcttgcct actcatttga caaaagaaaa
    29401 catgcctcta ggaatccaat ttatggctgc cagaggaaga gaagatttgc tatttcaaat
    29461 cggctatcta tttgaagcaa atcatcagtt ccatttacca aatccatgga aatagcagaa
    29521 acaaggagaa gaagaatgaa gaaaaaaaga ttgtttgctc taataactag tgcctttttt
    29581 attttaagcg cttgcggtac agctgccgct aatcaggaag ataacagctg gagtaatgta
    29641 gaaaaaaaga aagaattagt agtagcgact tctggcacac tgtttcccgc atcttattat
    29701 aatgatcaaa atgaattagt tggttatgat gtagatttgg caaaagaggt ggctaaacgg
    29761 ttaaatgtca aaatctcctt taaagaatac aacgtggatg gacaaatcac ttctgtttca
    29821 aaaagagaat cagattttgc tgcgaacgat tttggtatca caaaagaaag agaaaaaaaa
    29881 ttctcccttt cagagacttt caaatattca tttgacagta tgatcgtacg aaaaaaagat
    29941 gattcaggaa tccactcact tgaagatctt aaagggaaaa aagcagctgg cgaacccaat
    30001 actagctata tgcgtttagc ggaaaaacac ggagctaaat tagtcacata tgacaatgcc
    30061 acgaatgatc agtatttaag cgatgtagca aatggtcgaa cagatgttat tctaaatgat
    30121 tattatctgc agaaaatggc cgtatctgct ttaccagata tccctgtaaa aatactggag
    30181 aacgtttatt tcaatgaaaa cgaaagtggt tttttattga aagaaggaaa tgatgctctg
    30241 aaaaagaaaa tcgatggcgt attaaaagag atgaaagaag atgggacgac aaagaaaata
    30301 tctgaaaaat attttcaaac tgatgtttca gtcaaaccga aagaaacgat ggctgagtcg
    30361 gtgagtgagt gatgtacttt cctctaattg atttttccct catgtggact tcacttcctt
    30421 tcgtactgca aggcttggta tacacattag ggattggctt cgtgtcgttt cttttaggaa
    30481 atctggtagg gttgcttttg acagttttag gtcttttgga ttggctgcct ctgaatgtat
    30541 ttattcgttt ttatttatcg ttctttagag gcattcccgc actagtcctg ctgtttctgt
    30601 tatattttgg gttaccttat caattaagtg ccttaacggc ttcagtcatc tgctttacga
    30661 ttaccagcag tgcatttatt ggtgaaatct atcgaggatc actagcaggc gtttcttcag
    30721 gtcagtggga cgctggttta gcttctggtt tttctttctt tggggtattg aaatatatcg
    30781 ttttgccgca agcttttcga atctcagtac cggcactcag taacgtagct atggatctag
    30841 tgaaaggtac ttcgttagca gcaacaatca cagtgccaga aatatttcaa aaagcaaaga
    30901 tcataggcgg tcggacattc gattattttt ctctctatat tttagttgca ctgatttatt
    30961 gggtcatttg tatcgggatc gaaaaagtgc aacagtattt agaaaaacgt tctatgcatc
    31021 agtcaatctg aaaaatagaa atggtgctag cgtggctggc accatttcta ttttttgttt
    31081 cttgtatatt ctgcctagta ttttaaaacc atttcatgta aaatgtaaat cgaaaatatg
    31141 ttcggaggta gaaaacatga agaccccgct aaccatcgaa atagaatcct cgttatacca
    31201 atattgcatc gagcaaggcg gcttggttgt agaagaagtc acgatgcctg atgaccaagg
    31261 aattgtagat acgcttagct gcttgacaaa atttgatgga agccgagaat ggcgatgcta
    31321 tgagctgaaa gtgacaaaag cagattttcg ctctacagcc aaactgtcat ttgttggaca
    31381 ttataattat tttgttttac caagtaaact atatgaagaa gtaaaaactg aaatccctac
    31441 aggaataggt gttttagtgt atcgtccgta cacggttgaa gaggagatgc ctgcctctgg
    31501 tacatttctg attgcgaaaa aagcagcaaa gaaagagctt gctgtaccgg aagaagcttt
    31561 gacaaaccgc ttcatggctt ctttattcag ggaagtaaga aaagcaaagc aaatggagcg
    31621 aggcgtaaaa tattttccaa cagatcaatt gtacaaagaa ttgaaaagac gttcagaaaa
    31681 tcaagatcca ttttctaacg aacgatatta tgaacggttt ttagaggaaa tagctagtca
    31741 ggcaatcaat gagttgcaag aagaagttat cgcgcttcag catgattatg aatatttgag
    31801 gcaacaacag cagatccgtc ggttgcctac agagccattg gagtgaaaaa tatgtactat
    31861 ccttatttaa gaggaaaaca atttgaccta ttagcattaa aagaagcact gtcgcgagga
    31921 ttgctctcca ataaaatcca accagtgatc gaaccagtac gtgattccgc tacgcttaaa
    31981 aatgtgatcg aattatttca aaaaaagcac catccaatcg ctgtgatcca aaatccccaa
    32041 gtaggacaat tcaaattatt cgatcagcat gtgcacagtt ggacagtcaa agaaaatagc
    32101 tctgtcgtcc ctgcacagat cttaacgcca gaaaatctca gtgaagtact ggattcacct
    32161 ccagcgtttc ttgttttcga tggacagcac tacccaaaag atacagaggt gtggaaacag
    32221 ttggcaggag ttgattcgaa atttttgata ccagatacta gtcgctttcg catctggctg
    32281 cccgaaaaca aaattgtgat ccgtgactct tttcaaacga gaaagcatgt tgaaagttat
    32341 gcagataaaa cagatgactt ttttagtgat gactatcttt ttttccacgc agacggatat
    32401 attggatttt ctgatttcac gatcgaaggt agccgttatt tcgataaagg gttccctagc
    32461 cgagcgcttg ctatccatct aacgtatatt gatgcttacg gcaatatacg cgtgaaacat
    32521 tttgtctctg acagtaacga ctctgctaaa gaccaagcat tgaagtttct tgaagcagga
    32581 gataaaatga aaaaatggat catgcgtcac catcatcaac tcttgattac ttcaggaatg
    32641 attgaattat tggctcttta ccagcaacaa aaattccctg gactgggagt gttgaaaaag
    32701 tggtcactta tgcatcattt ggaacttatt agtcacctgc tagatcatcc aaaagattgg
    32761 cttaaatatt attcaaaagt tcaggaacta tatgaagtga tccaatgatt agataatgta
    32821 aatgaaaaag gaatagaaaa gaggaaactg gatgtatatt cggcaaacaa ggaaagaaga
    32881 agtagaagaa gtggtagaaa tcattaatgc cgcagcggat ttcattgctt cgcaaggctc
    32941 tcctcaatgg caaaacgggc agaaaccaac aatagaaacg attttgaacg atattgaaag
    33001 aaaagaaagc tatgtattaa tagtggaaga tcaaattgct ggaacagctg cattagtctc
    33061 aagcgtggat cccgtttaca caaaaataga tggtagttgg aaagaatcaa ctggtcctta
    33121 tttatcgatt catcgtgtcg ctttagcaga aagtactcga ggaaaaaaac tagcaaaacc
    33181 gttcttagaa catttgttga cgattgcagc cagcaaaaat atccaagata tccgtatcga
    33241 tacttatcca gctaatgaac cgatggaaaa gaccatctat tctgctggat tcacttatca
    33301 agggatgatt gaatttcctt ttgaacacgg cgaaagaaaa gcatatcaaa taatcatcaa
    33361 ttgactataa aatcatctga gcaaagataa agacattaac actactgaaa aaaacaatca
    33421 tatgatagcc aagaggttgt aacagaagtg gccagcttca aaaaacaaga aagaatttcc
    33481 gaaaatgctt ctcaaatttt tgtggaattt tagcgtattt tacgaaatag ctgctttctg
    33541 aaactccctt catcgagagg tcgtgacata gcttttgtca cgacctctcg gcttatccta
    33601 cgagtattat tcgatacatt tatatcaata atcctttttt tattttatct gcagcttctt
    33661 ggaacgctcc atcgtttgac acgactaaaa gtgaggggat agctttcaaa cgtttcaact
    33721 gtgctaaatc ttctacataa accgccagtc tggctgaaat ctgttcagat gaatctccac
    33781 gttttttcag gcgcgattgc aatgtttctt tagagatcgt aataaagata ggacggacta
    33841 ccgtcccgaa atactcatat aaatgccaaa aaccatttgc tgtcaaaacg gcgtaacaat
    33901 ttcctactgt cagtttcttt ttaatttctg ctttactgga accatattta tgttgagcat
    33961 attggtccca ctctgcaaac tcatttccct tgatcatctg attgaatgta ttgtcagaaa
    34021 caaaataata atcctcttga tctttttccc caggtcttgg tgatcgattc gtgtaagtaa
    34081 tgatcttttg ttccggctga aaaatagctt ctgcgagtga agtttttcca gaaccagaag
    34141 gaccgataaa tacatagcaa taattcattg tcatttctcc tttgatgatt gaacaagtga
    34201 aaaagctttg gaaaatattt ccaaagcttt taaaagtaac tttgcttttt tgtatattat
    34261 accagcaagc cagtcacaat agcacttaaa aagctgacta aagtcgctgt tagcaaaatt
    34321 ttcaatccgt gttttgcgac aagatttcct ttttcttcat ttaatccctt catcgcacca
    34381 gaaatgatcc cgatagaaga gaagttggca aatgaaacga ggaagacaga tataattgct
    34441 gttgtacgct cagtaaaatg gaaattacca tttgctaatt ctgtcatagc aacaaattca
    34501 tttgtaacca gtttagtcgc catgatacta ccggcatcca ctgcttcttt ccatgggatt
    34561 ccgctgatga aggcaagagg ggcaaagatg taacctagga tctcttggaa agtgatgccg
    34621 aatatcccgt ggaagatagc attgatcatg gcaatcaaag caacaaaacc gataagcata
    34681 gcagcaaccg tgatcgccac atggaaacca tcaagaatgt attctcccaa catttggaaa
    34741 aatgtctgtt ctttgttttc ttcaatgatc agctcatctt ctttttcttc taatacatag
    34801 ggatttacaa ttgaagccag aatataaccg ccaaataagt tcaaaacaag ggcagtgatc
    34861 acatatttag aatcgatcag tgccatataa gatccgacga tcgacataga aactgtagac
    34921 atagccgata cactcatggt gaacaaacgt ttctcagata ggaagggtaa ttcctttttt
    34981 atggaaataa aaacttccga ttgtcctaaa atagcagaag ctactccatt ataagattcc
    35041 aatttgccca tcccgttgat tttacttaat cctagaccaa cagctttcat aaataatgga
    35101 agaatcttga tatagcgtag aataccgata atagcagaaa taaatacaat tggcatcaat
    35161 acggaaagaa agaaaggtgc acttccttta tttgctacac cggcaaaaac aaagtcaaca
    35221 ccttgcccag caaaagcaag aagatgatca aacatttttg ccaatacaga aacaaccgct
    35281 gtaccaaaag ttgtacgtaa taatacgaaa ccaagaacaa gctgtaaaac gaacatcaca
    35341 attagtggtt tcaatttgat tgcttttttg ttactgctga tcaaaaaagc aagccctaat
    35401 gtgacaaata aaccaataat acctaataaa taactcaaat aatcactcct attccaaatt
    35461 ccgttttatt ttacctgttt tgcaaataaa atactaatct ttagtgaaat tttcattact
    35521 tttttagagt gaaacgcatt cattttccat tagaaaataa agcgaacaaa ataaaaggtt
    35581 taaaaagtgt aacgtcttag taaagtctat aaaaaaacga aactatcgat taagctaata
    35641 gtttcgtttt caacatttat aagtaaactt tttctattgg taatatagat tttcggaagg
    35701 gtagacaggt gcgcaggtaa tatcgattcc tagttttttc aatgtttgtt catcattttt
    35761 attgaccatc acagtagagt gggcttgtgc tccctcaagt tcagctagtt tatcataagc
    35821 aacttgagcg attggattcg ttactgcact gattgataaa gcgatcaaga cttcattgat
    35881 gcttagtgca tccaaagagg aatgaagtgt ctttgatttc aatccttgta ttgtttcaag
    35941 aactaatggt gacaataaag gaatgtcatc tgcgatatgg gctaaatgtt ttactgcatt
    36001 taagataact gccgctgacg catccatcaa tgaacttgta cgcccggtaa tgatgacttc
    36061 atctggtaat tcgattgcaa tcacagcaga aggatctttt gtaggacttt gcgcttgaat
    36121 cttatctgca tagtcatggg cagggactac cacgtttcgg tcttcaggac gtaaaccgac
    36181 ttcttccata atcagtttga ttcgattaac tgcttcttcg tcgatcaatc cttttttgaa
    36241 gtcgcattct gtttggaaat aacgacggat gatttcttgt ttagaggctt cttggacaac
    36301 ggtatcatcc acgatcccaa atcctacacg attcacaccc atgtcagtag gagattgata
    36361 aacagattct ttaccagtaa ttttttcaat aatacgtttg attacaggaa atgtctcaac
    36421 atcccgatta tagttcacag ctactttatt gtaggcatca aagtggaagg aatcgatcat
    36481 attgacatct tttagatcga ctgtggctgc ttcataagca atgttcagcg gatgtttcaa
    36541 cggaacattc catactggga aagtttcgaa cttggagtaa ccagctgcat gtcctttttg
    36601 gctttcatga tacagttggt tcaaggaagt agcgagcttt ccacttcctg ggccaggagc
    36661 tgtcactaca acgattggtt tagttgtttc aatatactca ttttttccaa aaccatcttc
    36721 tgagacgatt ttttctacgt tgactggata gtcttcgatt tctgagtgtt tatagacctt
    36781 gatgtttcgt ctttctagtt tattgataaa gactttcgtg gcaggctgtc cactatagcg
    36841 agtgataacg acactgttga ttaataagcc ataaccacgt aattcatcga ttaaccgcaa
    36901 gatatccata tcataagtaa tcccataatc accacggatc ttattacgtt caatatctcc
    36961 agcatagacg caaatcagta tttcagcttg atctttcaat ttttgcagca atttgatttt
    37021 cgcatcttct tcaaatcctg gaagtacacg tttcgcatgc ttgtcgtcaa ctagcttccc
    37081 accaaattct aaatataatt tgtcatagtg gttcactcgt tccaaaatat acgctgactg
    37141 ctcttcaata tatttttctg aatcaaaacc aatttttttc actaggttcc ctccttaagt
    37201 actaaagcat tttttcattt ttttgaggat tcgtcaactg gaagagcgaa attcctcaaa
    37261 aaaacaaaga aaatggttta aaccaacttg tctagatagt tattcattgg tatgatagtt
    37321 tttgataagg aaggtgctac atgaaaaaaa gacagaaaaa gaaaaacgca tataaacact
    37381 atatccgttc gatttttacc ggttatgaaa gaatgcttga agatcccgaa ttggaacaat
    37441 tgacgtttac ttatctaaac gaagaaacgc agctaactcg tgatgagcat cagcgcattc
    37501 atttcacaac aagagatctg cctagtaaat aaaaaataag ataaaggtca tcggattcga
    37561 ttctgtccta tcagatggaa agactagttg atcgaaaaaa aggctgtacc aaattttggt
    37621 gcagcctgtt ttatggagca ttgcccgctc ttttttataa caatttttta cagaaaatgg
    37681 tactattgaa gtattaataa gtgaaaaaca gatgagtaag aggaggcaag tagtatgaaa
    37741 gagccagata caaatgcaaa ttatgagcca gacgaactag aggagacgaa tgcggatcag
    37801 gatacaggac aagaatcgtc ttctttttac gatatcaaag aaaaagcaag catgaatctt
    37861 tcccaattat tagaagactt acaggctttt gaaaaagctg tccgcgaaga agatatccct
    37921 gagatctacc gtttatacaa tggccgattg aatgaagaat taaaaagaag ctcaaatgaa
    37981 aatcacgaga tcgatcaatt gctgatgcgt aagatccatg atcgtttttt acaggaattt
    38041 ccttttatgg aacaagtaga aaacatctcg ccaacgatga gctattacaa aatcggcact
    38101 tattaccatg atcggcccac ggtcggtatt gatgcaagtc tgccagaaat ttttgttttg
    38161 cctaagatcg atgaagagtg ggagaaatat tcccaaccgg agtcaacgga ctatgacaaa
    38221 aaaatcaatg agctagacgc aaaggtgatc actgctcaga cagaaattga acgtttagat
    38281 gaacaaataa aagaaatcaa tcgacaaatg actgatttga acgacaataa aggattcttg
    38341 aatcgtaaaa aaatcgagga agaaattcaa gaattagaga agaagaagca agtactatct
    38401 aatgaaaaat taggctggct tccttatatt gagacgcctg aaacaatcca gcagcaaaaa
    38461 gaagcattga agcaagaagc aagagcagac cagcttcgtg cagccatcgt agaaaaagaa
    38521 caaaggcaaa tcagacgcta tttcggtagc aaagagggat tcggtcaagc aatccatgaa
    38581 ttcttgatga attatcttgg caatgagaat cctaataatc aatctaatga aggaggttcc
    38641 gagtatgaat gaacacgatg aagcagaatg gacaaaaaat gaagaacaaa cagaagatca
    38701 tgaagaaacg aacacttcat tggaagaaca aacaagtaat cctctggatg acacagaaga
    38761 aatccctatg ctagaggaaa caaaaataca cgaaaaagaa aaagtaactc cgacgaatac
    38821 gaatactgca gaaaacaccc atgcttacga aataactgaa aatcccgggt atttagaagg
    38881 aaaagagcaa gatcatcaag atatcgtcag tttgattgaa acagcggaag cagaattagc
    38941 ggatttacgt atgagaaaag atttgatcga atcagatttt ccacaattat tagaatcata
    39001 tgatcgtttt atattgaatg aagaaccaat ctccacgatc ggaaagacaa gcctgatcga
    39061 atacttcacg tatgaattac tgaaaccgtt gaatgatatt ggtctggaac ggtcaaattc
    39121 agcttatgac acatggaaaa caagacattt ttcgatcaat tatacgttga atggacaaaa
    39181 cgaattagtc ttttcctttg tattaccgac catcgatcaa cgataccaag tggaatcgat
    39241 gagtctccta aacgtatcac cagagacaat ggaaatcaat gtccaagatg accgggtgct
    39301 ttctttgatc cgacactggt cagtggatcg agtattctct gcagggcaga tcacgatatt
    39361 caatcacaaa ttgaatcaat tattagccca tgcaagaaca cttggtttta ccgttaatca
    39421 gacattacta gacaatacga agccacttcg tttgaatctt cagagcgaat ttgaattgac
    39481 gaatgaagta ttggatgata tttttatcgt ggcaatgaaa aatccatcct acgatatgga
    39541 aaagatcaac gaaactactt atcaagtacg attagataaa ggacagtctt taacgataac
    39601 aacaaacgaa aaagatcaaa cagtcttgtc gatctcatct ggagactacc cacgatctgt
    39661 cattgatttc tttatcaatt acgaattctt ggtcccatta atggtgagaa agtcctgatt
    39721 ggataagttg gattaccaga tgtcattcag ataattctgt tccaaaggac ttgcggcagt
    39781 tatccagaat aattgtcaca agtcttttct gtatgtacta aatggacgtg aataacttgc
    39841 tgatgaagga gggatttcat taggaatgtc cacaaataaa atagcacagc ttagcttatt
    39901 gtctgctgct tgtgtagcag gtaggatcgc ttttcaattt attccgaatt tccagccaat
    39961 gactgctatt tttttattta tagtacttta cttaagctta aaagatgcgt taattgtcat
    40021 gagtctttct attgcgatca gcagttttta ttttggtgtt ggaccatggg tcatcggcca
    40081 atggatcagc tatactgttg ttctgagttt gttttcaatc gtctgcttga gaaaaacagt
    40141 gcaaaggaat ctatggttaa agggagtctg tttttttctg gcgggcatgg tttacggaat
    40201 aggtatgacc gtttttgata cgctgttata tcgtttgcct caaccttgga tctattacct
    40261 tcaaggggtg tcgtttgatt tgatgcacag tataggcaat gttgtgttct ttcttgtttt
    40321 tctgccagtc gtcaaacgtt tttacaatca ttcaggagga aaaaatgaaa aaaataattt
    40381 atagtttgct tgcaatgagt gtcagtatac tcattttgac aagttgcagt acaacctata
    40441 cacaatcggc ttccaaccaa aaggaggaag taaaaacatc gcaaaaagca acaatcacgt
    40501 tacaagaaaa tggtcaaaac ttttcggaaa aagaagtgtt cttcaaaaaa ggcgatgatt
    40561 tactgagtat tttgaaacga aattttgaag tcaaagaaga taacggcttc atcacttcgc
    40621 ttgaagggca ctcacaggat gagaaaaatc aactctattg gatgtttact gtggacggga
    40681 aaagtgctac tactggtgcc aaagagatca aattgaatga tggacaatcg gtcattttca
    40741 atttgtctaa actataagtt tcataaaaaa ctgttaaagg gcgaatattg ccataattca
    40801 gtgagttcag ttgatgaaag aaggaaaata acatggaaaa ttttaaaaaa agcggaatgt
    40861 tttccgtaat tgctgctcta ggggctaata ttctagttgc tatcagcaaa tttgtcggct
    40921 atgcaatcag tggcagtgcc gccatgctaa acgaaagcat ccacagtatc gttgattgca
    40981 gcaatcagat tttgctgtta ttcggtgata aacaagccaa taaaggacag agcgagttgc
    41041 atcaatttgg tgaaggacga gcaaaatact ttttcagtac aatcgtcgca atgatgcttt
    41101 tcttcggcgg tggggcactt ggggtgatgg aagcttttga aaagttgacg catccatccc
    41161 atgaagtggg taatccgatc attgttatag caatactgtt atttggtttg gtaatcgaag
    41221 gaagttcgtt acgcgtggca atgaaagaaa tcaaagaatt gaatactgaa aaactttcca
    41281 cgatgcgctt tttgcgcgaa agtcgacaca gtgaaatact gattattttt acggaagact
    41341 tgtgtgctgt aatcggtttg gtcttggctt tagcaggaac aatattgact tatgcaaccg
    41401 ggattgctgc atttgatgcg atcagcggat tgctgatcgg tttcttgctg atgggagccg
    41461 ccattttcct agcaaaagaa ttttatagtc tgatcatcgg tgaaagcgtg acagcaagcg
    41521 atttatcaaa aatcaagtta gcttttgaac gtcctgagat cagtcggctg atcgatataa
    41581 aaacagttca tttaagtcca acggagattt tagttgcagc aaaagcagat atcgttggta
    41641 acaaagagaa tgaagcttac tcggtcatca atgatattga aaaaaatatg cgtcagtctc
    41701 ttcctgacaa gaagatgtat atatacattg aaacagataa atatgaccca aattattctc
    41761 gtaaataaaa cgtttattca tgaattgaag caaaaatgag aaaaatataa tcttgttttt
    41821 aaataaaacg gctacaattt agcgaattta tgttacaatg agtccgctgt ttatttgttg
    41881 taattaaagg agatatttta atgaacaaaa agaaaagtgc gccatggctt caagctttgc
    41941 atgcagtgat gccactttgt ataagctata taccagtagg attagcttgc ggagtattgt
    42001 tgcaaaaagt tggatttgat cctctcttat caggactgtt atcgattctg gtcttttccg
    42061 gtggcgcgca gtttttagtt gcatctatgc ttacgacgca agcatcattt gcaacgacat
    42121 tattgatggt tttcttttta gaattacgct atacattatt aggagcaagt cttgccggtt
    42181 ttatgaaaaa agaaaagcgg acgtttttgg ctgtcttttc tcaatcactg aatgatgaaa
    42241 actatgcggt gaactactta aagttttcaa ctgacccttc ctggaataaa agaaaggctt
    42301 tatatgtcaa ttggttctca atgactgcat gggccggtag caatatgatc ggtaattttt
    42361 tcggctcggt gattcgagta gatgctgacc ttgtccattt tgctttgacg gccatgttca
    42421 ttttcatgtt tatcatgcag atgaaaagcg cactactgat ctttacaggt ttattctcag
    42481 gcgtattagg ggtcgtattc atggtattat tccaaaatac tttcggattg attgcagcaa
    42541 cagtcattgc ttcatttgcc ggatttatgc tggagaaggc attcaaaaaa gaaaaagcta
    42601 agaaactaag agaccgcggt aaagatgtca atgagccgct cttcaacttc ccggaacagg
    42661 aggccaatca ccatgactaa actatatttg ctacttttag ttgcttgtct gttcatcgtg
    42721 gcatatatcc cgcgcttgtt cccgatgctt tattttactc atcgaaaagt gccatcctgg
    42781 ttcagtgact ggatgaaata tgtaccggtg gcattatttg cggcgttagc ttttaaagat
    42841 gttttcatta ctcatgaaca tctggatatt gcttggaata tcaaaatagc tgcaatgatt
    42901 ctagtagcag gcgtggctta caaaacacgt tcgatggcgt tgtcagtttt gacaggactt
    42961 gcgtctgtct ttttgctgtc tatgctttaa actgttttat tttattaaaa acagagattg
    43021 cgacataagt tgttcaaact gatctatccg aactgcattt gcaacagtca attctggatg
    43081 caagtttatt cgtagggata aaaaagatta gtgttggctt atgatgcaag ctctttttta
    43141 ttttaggaat tagagaggga tttgtccttc tatgattttt tgctataata gggaagatgt
    43201 ttattttatg aaagaatagt tgagggaatt taaatgaata aaaaattgat gcaaggaaca
    43261 ttttggctaa cctttgctaa tcttctatgt aaagttttag gggtagtcta tttgattccc
    43321 tggctaagta tgatggggaa caatcaagat ggtatgcttg ctacgacatt gtataatgtt
    43381 ggctatcttc cttatggatt gttcctgatg cttggtacag tcggatttcc aaatgcgatt
    43441 gcaaaaaaag tagctgtagc cacaaaagaa ggagataacg ctgcttgtcg gctgattttt
    43501 agaagtacga tcaatatcat gtttgtcatc ggtatcgcct ctgctgcact gatgtattta
    43561 tttgctcctt tactagccgg aatcagtccg attgctaacg ttaataatgg gatactagct
    43621 atcagaagtt tatgcccatc tttgattgct atcccaattc ttagtgcaat gagaggatat
    43681 ttccaaggaa aaaatgatct gcggccttat ggaacttctt tgattatcga acaggctgtg
    43741 cgagtgatcg ttatcttggc tggtacttat tacttgcgcg tattgactga cggaaccata
    43801 ttagaagctg tattgatcag tacagtcgct tctttcttcg gtgggttagc tgcgattatc
    43861 catatgtata tcgtcggacg cagaaaagac ttcttcgaac ttaaagattt tttgatttcc
    43921 agccgttatt tcgaaagaga aaaccgatct gcctctgtct ctatcattcg ggaaacacta
    43981 ccgtttattt ttgtcggctc agtcattact atcgttcaaa tgatcgacca agtaacgatg
    44041 aaaccactgc ttcacttttt ccgtccagag atcgcagatc agcaactgga attcttattc
    44101 agccgtgctt ctgtcaatcc aaataaattg acattgatcc tgatctccat ggtaggaaca
    44161 gtagctataa gcagcttgcc aatattaagc acgatgaaga aaaaagatcg gatacaaatc
    44221 gaaaaaacag taggagatag tttttcgatt gcgttattga ttcttcttcc ttcattgact
    44281 ggaatgtctt tattagctgg accactatac acattgtttt ttggctatga tcctgaaagt
    44341 gtcggatatt tccaaatggc tttgctagct tctttgtttt tctctttatt cacgatccta
    44401 tctacgatgc ttcaatcttt gaatcaccat cgttttgcga tccgattaac tgtagaagca
    44461 attatcctga aagtcatctt ccaagtaatc ggattaggat tagttggcgg atacgggatg
    44521 agcttatcaa atggcttagc attcggtatt gtctttgttc gcggctatca ctttatgtgc
    44581 aaagaatacc gaatagcacc tttagcaaag atcagcaatt ttttcttaaa aactttccgc
    44641 tccaccctga ttatgcttgc agtatgtttt gccgttttct ttttgctgaa tcagcgattg
    44701 tcaatggaat caaaaagcta tgcaatgatt tattgtgtgg ctgtaggaag tattggcggc
    44761 ttagtatttt tattttctca attcggaaaa aatgggtttc gaatgttgaa aaatgttaaa
    44821 catcatagca gaagcaaaga ataggttaac taatcgtttt ttgctgtcac ttgaaaaacg
    44881 gcaactcgta tgattacgct tgtcgttttt ctattttcca attttagttt catatctaat
    44941 cttacttatg atatagttat aaggtctgga aaaattcttt gaaacgagga aattaaacac
    45001 atgaaacttg cagtagttac agatagttcg gcatatctgc cggaacgtat caagaaccat
    45061 cccgacttat tcgttattcc aatccctttg attatggatg ggaaaattta taacgaagga
    45121 atcgatatcg aagcggatga atattatgga cttttaaaaa acagtaaaga ttttcctact
    45181 acttcacaac ctgtcgtagg ggaagttttg ggtttatatg aggaattgaa agagaaaggg
    45241 tatgacacga ttttaagtat ccatctttct tcagggattt ctggctttgt caacacatta
    45301 tttgcgatga aagatgacat cagcggagta acggtcattc cttatgactc taagatcact
    45361 agtatgccga tgggacacat ggtagaagct gccttagact taaatgatga aggtcagtcc
    45421 cttgatgaaa tacttgcaca tatcgatcga atccgagata atacctacgc ttatctgatt
    45481 gtagatgatt tgaacaattt agtacgagga ggacgtttga caaatggtgc agcgctgatt
    45541 ggcagcttat taaaaatcaa accgatcctg acattttctg aagggaaaat tgttttattc
    45601 gaaaaaatcc gttcaagtaa aaaagcattt gctcgagctg aagaaattat tggtagaaga
    45661 aataacgaaa tacaaccgcc agtcaaactt tacgtgatac atgcaaataa tttagaagta
    45721 gcgattgcgg agaaagagaa attgcagaaa aaatatccaa atgcagaaat cgaaattggt
    45781 catttcggac cagtcattgg tacacattta ggtgaaaaag ccatcggcat tgccatttca
    45841 gcgcaataat tccttttatt caaaaaacat accaaaaata ttccaacatc atcttggact
    45901 ttctacatgt tactaatgag cgtgtaaaag aacgagatgg tgtttttatt tctatcaatg
    45961 aagctctttt tctttgcaat cctcacttca atcctctata atgtcgcata tagtttagta
    46021 aatgagtaaa ctactaattt acttatttac taaaaataaa aggatgagga gttaaaataa
    46081 tggaaatacc aacaaattta aaacataaac cagtaatcgt tgtagaagac tatgataaag
    46141 ttgatggaag aaatgcatta aatacggatg caaaagggct ttcactgggc cttgctcagt
    46201 ggaatgatcg tggaaaagtc gatatctcag gcaaggtatg gcgacatact ggagaaaaat
    46261 ggtcacgaca gtcggaagaa ttaccaatca cacgtatttt agatttagcg atcttagctg
    46321 cacaaggaag tttatacttc caagatgctt atcgttatga aaaattttat gatccagaaa
    46381 atccagtcgt agacatcatt ggattacaag ggaaccgaat gacggtagaa gtagatacca
    46441 aaaatccaaa gatcgatgaa gacatcattt tgtattacga tacactacaa aaagacggag
    46501 aactgattgg ggaacgattc cgtattttaa aacgtctttt agatgagcta ggatattaat
    46561 agacagagat gatcaaaagg ggaagagaag catggagaat ttctcactaa cagaaaaccg
    46621 aaccttttca cggctagaaa agcaaatgat ctggaagaaa ccgaaaagcc atcggacaag
    46681 tgcagaagaa tggcggatcg cctccgaaat caaagggaat tggcaagatc ctgaaatgaa
    46741 aatcagtaac gtacttttgg aaggagatgc cgggtcgggg aagacacaat tagccaaagc
    46801 actatctgct gatctgcaac ttccctatac aaaagtgacc tgttttgcag atatggacaa
    46861 atcagatgtt ttcggagcct tattacctgt agtagattct aataaggaac aagaccaaga
    46921 attactagaa gctatttacc aaacagatac acttgaagct gtactgacac tgatccagaa
    46981 ccattacggc attgatcctt tttctgctaa agaaaaatta gcagagctag ttcaaaggat
    47041 cgaagctgat tatccagatg caatccatta cagctattac ccttctgaaa tcgttcgagc
    47101 gattgaaaaa ggatatttat tagagattca agagccgact gtcatccgag atgcctctgt
    47161 tcttgtggca cttaactcag cgctcgaacc aaatgggatg ttgaatttac cgacaggaat
    47221 cattcgtcgc catccagatt gcgtcattgt gatcactaca aatcgaaatt accaaggaaa
    47281 tcgcccatta aatgaatctt taagagatcg gatgcaacat gcggaaaaaa tggatcttcc
    47341 tgccttagaa gtcatggcag aacgtgcgat ggcgaaaact atgatccaaa aacaagaact
    47401 tctcttaaag atggcagaga ttatccgttt gttggatgaa actgcaaaag ctaacgccat
    47461 caaaggtgta gcaggaatgc gttcttattt ttattgggca aatacctata agcaaggaca
    47521 agatttactc cagtcgattt atccaaaagt tttgtataaa ttatccactg attcagatga
    47581 attggcaatt cttgaacaag ctttgtctga cagtggattg ctactggaac ttcaggacat
    47641 attgagaaaa gaaaaatggg gtcatcctca atctgagcat acaaaaggaa gaaccattag
    47701 cgccgaagaa gcaaatgaac gaaacatcac tgaaaatgct gaagaaattc tgcgcttaga
    47761 tgaaaagaaa tcgttgtctg ctgaagaacc aaatgaggga gaagagaaac aagaagaaac
    47821 aatagaaaaa aacgagattc ctcctcaaat gcaaaaagaa cgcagtagcg atatcgaagg
    47881 aaaaaatcaa aaagaacaac aaacaggaga tgattctcaa gaaatgtctg cttctgacat
    47941 ggaagcacat gataaggaaa tcaagaagca actgaataaa gaagcgcgac aaatcatgaa
    48001 ggaaacgatt catgaaaaag aaggtctcat cgttcaccga ccagctttcc aaggaaaaac
    48061 gccggaagca cgtgagctac acatgcaagt aatgccaata gtagaatcac ttagccggca
    48121 aattttagag ttactggata atgaacaaac agagacgtac caaaaaggaa aatacgaagg
    48181 tcagcggttc aatgcaagca aagtagcata tggtgatttg agaaattttg acaaaaagaa
    48241 cccgccacat gagcaacctt ctttagcggt agctgtacgg atcgatgaat ctgggtcaat
    48301 gatacgggat gatcggatcg aagcggcaaa aaaagcagcg attgccattg ccgaattttc
    48361 taagaaagtc gatatcccat tgttgattta cggagataca gcagaccgtt cgtcaagaga
    48421 aaagacttct ttgttttctt ataaagaatt tgaagacgga tttcaatggt taaatgaaaa
    48481 attagtcact atgaaaccaa ggcaaaacaa tcgtgatggt gctgcacttc gtttagcagc
    48541 agaaaaatta aacagacaat ccgcaacaac caaactgttg cttaatatta gtgacggtca
    48601 gccaaaagcg ttgccggatt atacaggcaa aaaagcaaaa gaagatatcc agtctgtttt
    48661 gaaagaatat gaacgtcaag gaatcctatt tgtctccgca gctattggcc aagacaaaga
    48721 agaaatcaag tcgatctacg gtgaaagtcg ttttgtagat attactgact tgaatgaatt
    48781 tcccaagcaa atgattcaac tgattgcccg ctatctatga taaaataaag ctcaacgaac
    48841 gcacttagca gattcgttga gcttttcgtt tctagttacc ggtaacaagg atacttctaa
    48901 aatagaatcg gttataatca agagggaccg ttaaaggagt gaaacgatat gatacaagaa
    48961 caaaaatggt ggaaagaagc agtaggctat caaatctatc ctgctagttt caaagatagc
    49021 aatggcgatg gtcaaggaga catcaatggg atccgtgaaa aacttaatta tttgaaagat
    49081 cttggtatcg gctttatctg gatcaatccg atctatcaat ctccatttgt cgataatggt
    49141 tatgacgtaa gtgactatca agatatagaa gagagattcg gaacgatgga agattttgat
    49201 ttattgctaa aagaagcaca tgaattaggg atcaaagtga ttatggatct tgtcatcaac
    49261 catagttcgg atcagcatca atggtttgaa gaatcgaaaa aatctaaaga aagcccgtat
    49321 cgcgattatt acatttgggt cgacggggta gatggcaaag aaccgaataa ttggacatcg
    49381 attttcggcg gttctgcttg ggagtattct catgaaactg gacagtatta tctgcatgtt
    49441 tttgcaaaag aacaaccaga cttaaattgg gaaagcgaga aattgaaaga agaactattc
    49501 aatatgatcc gatggtggtt ggataaaggg atagatggat ttcgtttaga tgcgatttct
    49561 catgtaaaaa aagatgaata ttcagtaaaa gccacagaga accctttctc accctttcaa
    49621 aatgtctcag gaatcgaaga acatttgacc gatttgaaac atgtttttga agagtacgat
    49681 atcatgactg tcggagaagc aagtggtgtc actgcagaag aaggaccaca atgggtaggg
    49741 aaagacggtt atttcgatat gatattcgaa tttgatcata tccatatctg gcagcaagaa
    49801 aaagaagggc aattagatgt ccttaaattg aaacttgcat taagcgcttg gcaaacttca
    49861 ttggatggta tcggatggaa cgctttatat atggaaaacc atgatgttcc tcgtgccgtt
    49921 tcagtgtttg gagatactcg tcccgatttt tgggctatgt ctgcaaaagc aatcgctatg
    49981 atgtatttct ttttgcaagg tacgccattt atttattaag gacaggaaat cggaatgacg
    50041 aatatgccct ttgaatcgat cgatcaagtt gatgcagtag attcgaaaag actttataaa
    50101 aggctgcttg cggaaggtaa gacaagagaa gaagcattgg atatcattcg tgaaacaacg
    50161 agagacaaca gcaggacacc catgcaatgg acttcggaac aatatgctgg tttttctaca
    50221 catgaacctt ggctgatcac taatccaaat accaaaacga tcaatgtaga acaacaagaa
    50281 tatgaaccag agtcggtcct gcaattctat aagaacatga tccgcattag acaaaccaat
    50341 aaaggtctga tatacggttc ttataaagaa tatcttcatg aacatccaca actttatgtc
    50401 tatgaaagat atttagaaga tgaacaatat cttattatgg taaacttaac agaatcactt
    50461 gctgactatg aacttccaaa agaagcagat cagtcctgga cattactctt gtcaaattcc
    50521 tctagcggag aatttgaagc taaaggcata ctagcacctt atgaagctcg gttatataaa
    50581 acaaacaagt aaaacttcct cgttaaagtt cattagttgg actttgcgag gaagtttttc
    50641 agattgctct gtcaattact catttcaata attcgctcta ggaccaccga tatatttagg
    50701 acgagagcga agggctgtca cgtgagcttg tccaagggtt ttcaaacgag gtctgacagg
    50761 tacttggaca tgtttgatat gcataccgat tgatgtgtca ccgatatcga taccggcttg
    50821 tccaactacg tgttccactt cgacaggatc attgaactgg tcaaaagcag caacagaaca
    50881 agcacctcca gcatgtagtg caggaacaac agagacaatt tcgaaatttt ttgcttctgc
    50941 cactgttcgt tctactacta atgctcggtt caaatgttca caaccttgga cagctagcgc
    51001 aatttcttta ggatccaaca actcttttaa cgtacggatg atccattgac caacttccgc
    51061 actggaattt tttccaatat gtcctccaac gacttcgctt gtgctgcatc ctaaaacaaa
    51121 aagatcacct tttttcaagt gtgcctcagc caatatgtta ttaactattt cagtcaattg
    51181 gtcttttaat tctttttctg acaacttcat tttctaaaac cttctttttc aattaatatt
    51241 gcttccgtgc ttgaatacgt tgaagacttg cagttatagg aaaggcaagt cccattccaa
    51301 tcagattttg gaagatgttt cctggtatag aagccactcc agccggccaa tcatataaaa
    51361 tccaaccggc gataccatag ccgatgatca taactaagct tcctaataaa agccctaatc
    51421 cccacatacg agtagaagat ttgctgaaag aaccagcaac atatccttgt aacccgtgga
    51481 tcactaatga aaaaactgcc cactgcggat atcctgaaat caaatcgatc aatagaccac
    51541 tggaagcacc aacaactaat ccacccgttg gaccataaag aaaagcagcg gtatagatcc
    51601 cggcctcgca taatgtcaca aatccattcg tagccggtac agggatcaaa attgttaatg
    51661 aaagggcaac tgtcaacgca atcagcatag catagatcgt taattgctta gttttcattt
    51721 ctcattcctc ctttttgaat accgccagac cagacacttc cggtatgatc gttcatcagc
    51781 acgccattag aaatacaatg ggcaacaaat tttttacttt ctgctactgc tttggtaaaa
    51841 tctgccccta acacaagatt cgctgttatt gcagaagaaa aggcacaacc ggccccgttt
    51901 actgttgtag tgtcgatttt tttatgagaa aatacctcat aatgatcaat tgaatagaga
    51961 agatccacag cttcatctcc agccatcctt gtgccgcctt tgatcacaat gttttttgtt
    52021 cctgaagcag tgagttcttt agcgagatgg atcatttctg ttaacgaaga gggaagagct
    52081 tgaccagaaa gtaaagcagc ttctgccaaa ttaggcgtaa tcatcgtaac aagtggaaaa
    52141 agttcttcga tgagctgcga aatatacaat tgattgatca cagcttcagt ttctttgaat
    52201 gccaaaacag ggtctaaaat gattgggata ttttgttttg tttttatgaa gtctcgaaca
    52261 accatgattg cttcacttga attcaataac ccaattttga taccatctaa tgaagtcatt
    52321 ttatcaatcg aaactaactg tcgtttaagc aattccaaag atatagattc cagcataaat
    52381 cgctcattaa tatctagtgc ccctatagaa gtcaaggcgc ttagtccgaa tagaccaaaa
    52441 ttctcaaaag tttttaaatc tgtttggatt cctccaccag caaatggatc agaaccgcca
    52501 attgtcaaga ttcttttcat aacattttcc tccatgaata agagtataac gaaattttca
    52561 aaaaagaaaa acagccaatt ggcatatttt tatctcatcc aatttaaaaa aacaaaaaga
    52621 aaagaaagac caaaatggat ctttctttcc ttaaatagtt aggacttttg tgattttaat
    52681 tctttctcga tttgaagccg ttgcactttc attgtagctg ttcgcgggat tgcatcaaaa
    52741 tcacggatga tagggacgtt caagcgagga agttcatgga cttgctccca ccatcgattc
    52801 caatccattt ctttatcagg agctaaagca ataatcggtt gtggagaatg atttttatcc
    52861 cttacaatca ctacttctgc caaaaaatct aacgaatcta ataaaaagtc ttcaatagct
    52921 aatgtactat tgatcgtttc gatcaaatcc acttgccgat ctttcaaaaa taggtggcca
    52981 tgcttatcca taaaaccgta atctccgcta tcccaccaat cgccataaac attttcctgg
    53041 aaccgtgcat cttccttgta ataagtcaaa gcccgtcctt tagacagtaa ttgtatatga
    53101 ccatctgtgt tttcaggtag gacattccca actgaatctg taatccgagc gcttgtcatg
    53161 tcttccagtc caacgcccat atctcttgca tcacttgttt tcaaactctc tagtgtatga
    53221 gccttaagaa tcattggtcc gcattcactt tggccatata cttgaagaaa taccgcatcc
    53281 tgtgccatcg acgttcgcaa aaatgtcttc attgtctggt tgtttatagc atcaaaagtg
    53341 gagtgatagt atcggatacc cgaaaaagct tctggatgct ccttagcagt aaaacgccac
    53401 tgaacaaagt tattcggatg ggtctctagt gcaattggcc ggtgagcttc caacatatga
    53461 acaacttttg aactttgtgc gtttgctaaa ggcatcatag gaaatcccat ggacatcaaa
    53521 gaagagatac caatattgaa tctggaatgc actggagaga tgtgaaaagc gattaatttc
    53581 ttttccgaaa tttttgtgaa aactgttttt tgccatttcg tccgccatcc catagaatga
    53641 gcagaatgac aaataagttt agggatacca gttgtaccag aagtatgggt catataagaa
    53701 atttcatttt tgtctaaaaa tgattgagaa acagacaaag caggttgttc cattaaataa
    53761 agaatag
//
LOCUS       DAPBBR010000017        52449 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPBBR010000017 DAPBBR010000000
VERSION     DAPBBR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.017"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1..794
                     /locus_tag="RD488_001008"
                     /pseudo
     CDS             1..794
                     /locus_tag="RD488_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            934..1860
                     /gene="cysK"
                     /locus_tag="RD488_001009"
     CDS             934..1860
                     /gene="cysK"
                     /locus_tag="RD488_001009"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDT7657100.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2096..2542
                     /locus_tag="RD488_001010"
     CDS             2096..2542
                     /locus_tag="RD488_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7657101.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2814..4166
                     /locus_tag="RD488_001011"
     CDS             2814..4166
                     /locus_tag="RD488_001011"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HDT7657102.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4337..4624
                     /locus_tag="RD488_001012"
     CDS             4337..4624
                     /locus_tag="RD488_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657103.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4850..5293
                     /locus_tag="RD488_001013"
     CDS             4850..5293
                     /locus_tag="RD488_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7657104.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5299..6483)
                     /locus_tag="RD488_001014"
     CDS             complement(5299..6483)
                     /locus_tag="RD488_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HDT7657105.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6751..7449
                     /locus_tag="RD488_001015"
     CDS             6751..7449
                     /locus_tag="RD488_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7657106.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7456..8133
                     /gene="nth"
                     /locus_tag="RD488_001016"
     CDS             7456..8133
                     /gene="nth"
                     /locus_tag="RD488_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDT7657107.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8259..8792)
                     /locus_tag="RD488_001017"
     CDS             complement(8259..8792)
                     /locus_tag="RD488_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657108.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9089..11470)
                     /locus_tag="RD488_001018"
     CDS             complement(9089..11470)
                     /locus_tag="RD488_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7657109.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11460..12107)
                     /gene="recU"
                     /locus_tag="RD488_001019"
     CDS             complement(11460..12107)
                     /gene="recU"
                     /locus_tag="RD488_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDT7657110.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12171..12710
                     /locus_tag="RD488_001020"
     CDS             12171..12710
                     /locus_tag="RD488_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDT7657111.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12800..13219
                     /gene="gpsB"
                     /locus_tag="RD488_001021"
     CDS             12800..13219
                     /gene="gpsB"
                     /locus_tag="RD488_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDT7657112.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13241..13608
                     /gene="rnpB"
                     /locus_tag="RD488_001022"
     ncRNA           13241..13608
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RD488_001022"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13817..14983
                     /locus_tag="RD488_001023"
     CDS             13817..14983
                     /locus_tag="RD488_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDT7657113.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15029..16525
                     /locus_tag="RD488_001024"
     CDS             15029..16525
                     /locus_tag="RD488_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HDT7657114.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16606..17289
                     /locus_tag="RD488_001025"
     CDS             16606..17289
                     /locus_tag="RD488_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7657115.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17934..19124
                     /locus_tag="RD488_001026"
     CDS             17934..19124
                     /locus_tag="RD488_001026"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDT7657116.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19226..20179
                     /locus_tag="RD488_001027"
     CDS             19226..20179
                     /locus_tag="RD488_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDT7657117.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20248..21597
                     /locus_tag="RD488_001028"
     CDS             20248..21597
                     /locus_tag="RD488_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7657118.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21780..22103)
                     /locus_tag="RD488_001029"
     CDS             complement(21780..22103)
                     /locus_tag="RD488_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657119.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22232..23395
                     /locus_tag="RD488_001030"
     CDS             22232..23395
                     /locus_tag="RD488_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7657120.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23465..24814
                     /locus_tag="RD488_001031"
     CDS             23465..24814
                     /locus_tag="RD488_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7657121.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24859..25290)
                     /locus_tag="RD488_001032"
     CDS             complement(24859..25290)
                     /locus_tag="RD488_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7657122.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25678..28320
                     /gene="alaS"
                     /locus_tag="RD488_001033"
     CDS             25678..28320
                     /gene="alaS"
                     /locus_tag="RD488_001033"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDT7657123.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28520..29116
                     /locus_tag="RD488_001034"
     CDS             28520..29116
                     /locus_tag="RD488_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7657124.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29238..30386
                     /locus_tag="RD488_001035"
     CDS             29238..30386
                     /locus_tag="RD488_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7657125.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30424..30837)
                     /locus_tag="RD488_001036"
     CDS             complement(30424..30837)
                     /locus_tag="RD488_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDT7657126.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30916..31347
                     /locus_tag="RD488_001037"
     CDS             30916..31347
                     /locus_tag="RD488_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HDT7657127.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31446..31679)
                     /locus_tag="RD488_001038"
     CDS             complement(31446..31679)
                     /locus_tag="RD488_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HDT7657128.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31862..33532
                     /locus_tag="RD488_001039"
     CDS             31862..33532
                     /locus_tag="RD488_001039"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDT7657129.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33679..34065
                     /locus_tag="RD488_001040"
     CDS             33679..34065
                     /locus_tag="RD488_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657130.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34052..34750
                     /locus_tag="RD488_001041"
     CDS             34052..34750
                     /locus_tag="RD488_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7657131.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34755..35219
                     /locus_tag="RD488_001042"
     CDS             34755..35219
                     /locus_tag="RD488_001042"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDT7657132.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35216..36127
                     /locus_tag="RD488_001043"
     CDS             35216..36127
                     /locus_tag="RD488_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7657133.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36362..36901
                     /gene="pyrR"
                     /locus_tag="RD488_001044"
     CDS             36362..36901
                     /gene="pyrR"
                     /locus_tag="RD488_001044"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDT7657134.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36915..38198
                     /locus_tag="RD488_001045"
     CDS             36915..38198
                     /locus_tag="RD488_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDT7657135.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38211..39137
                     /locus_tag="RD488_001046"
     CDS             38211..39137
                     /locus_tag="RD488_001046"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDT7657136.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39156..40436
                     /locus_tag="RD488_001047"
     CDS             39156..40436
                     /locus_tag="RD488_001047"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDT7657137.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40441..41517
                     /gene="carA"
                     /locus_tag="RD488_001048"
     CDS             40441..41517
                     /gene="carA"
                     /locus_tag="RD488_001048"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDT7657138.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41522..44707
                     /gene="carB"
                     /locus_tag="RD488_001049"
     CDS             41522..44707
                     /gene="carB"
                     /locus_tag="RD488_001049"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDT7657139.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44761..45537
                     /locus_tag="RD488_001050"
     CDS             44761..45537
                     /locus_tag="RD488_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDT7657140.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45534..46466
                     /locus_tag="RD488_001051"
     CDS             45534..46466
                     /locus_tag="RD488_001051"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDT7657141.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46463..47179
                     /gene="pyrF"
                     /locus_tag="RD488_001052"
     CDS             46463..47179
                     /gene="pyrF"
                     /locus_tag="RD488_001052"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDT7657142.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47186..47815
                     /locus_tag="RD488_001053"
     CDS             47186..47815
                     /locus_tag="RD488_001053"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDT7657143.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47803..48117
                     /locus_tag="RD488_001054"
     CDS             47803..48117
                     /locus_tag="RD488_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657144.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48155..48796
                     /locus_tag="RD488_001055"
     CDS             48155..48796
                     /locus_tag="RD488_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7657145.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48839..49531
                     /locus_tag="RD488_001056"
     CDS             48839..49531
                     /locus_tag="RD488_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HDT7657146.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49528..50430
                     /locus_tag="RD488_001057"
     CDS             49528..50430
                     /locus_tag="RD488_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7657147.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50588..52294)
                     /gene="efbA"
                     /locus_tag="RD488_001058"
     CDS             complement(50588..52294)
                     /gene="efbA"
                     /locus_tag="RD488_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HDT7657148.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17146 a         9140 c        11269 g        14894 t
ORIGIN      
        1 ggaacgagtc ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca
       61 gatgaacaag gatctcaaac agttgctgat cctcaagcgt ttatcgatca aatcggctgg
      121 tctgcgtcag aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg
      181 ttgttggaaa gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc
      241 ggtgtgaaag gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaacg
      301 gacaatgggt aacgatgaat gaaccattcc gaaaatattc ttcttattgg gaatccttcc
      361 aagaccatgc gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg
      421 gcgtgtggaa aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt
      481 atgctaccga tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa
      541 cccgttttga tacgccatca acaggttcgg ctaccacaag tacaacaaca acgactacta
      601 cgacgacttc aacgtcatca tcttcaacaa cagatgtaaa tacaaataat ggtcagacat
      661 atacagtcgt gtcaggtgat acgctatggg atattgcaca aaaatttggc atgtctgttg
      721 atgatctaat ggcgaaaaat ggcatgtcta tgtccagtta ttctttatta gttggtcaag
      781 aactaaacgt ttgatttaga taaaaaggca aagaaactac catatatggt atatctttgt
      841 cttttttttg ctagtcaaag acgaatcact cgccataaat gaacagattg tattatgata
      901 agtaagaaga gcaaagacaa ggaggaattg aagatgacag ctatctataa ctcagtcacc
      961 gaattgattg gcaaaacgcc aatcgtcaaa ttaaataaaa tcgtaccaga agattcagca
     1021 gatgtttttg taaagcttga gttttttaat ccaggaggaa gtgtaaaaga tcgtattgct
     1081 ttaagtatga tagaaaaagc agaacacgat ggtctactga aaccaggtga tactatcatt
     1141 gaacctactt ctggaaatac aggaatcgga ttgtcgatgg taggagttgc aaaaggatat
     1201 aaagtaatca tcgtgatgcc tgagacgatg agtatcgaaa gacgtttatt gatgaaaggg
     1261 tacggcgcag agttgatttt gactcctggt gcggatggta tttctggatc aatcagagaa
     1321 gcagaacgtt tggcaaaaga aaacggctac tttttaccat tacaatttga aaatgaagca
     1381 aatcctcttg tgcatgagaa gacgactggt cctgagatac atcaagcatt tggagtaaat
     1441 ggcttggacg cgtttgttgc aggtatcggt acaggaggaa cgatcactgg cgctggccga
     1501 gaattaaaac gtgtgtatcc gaaaatcgaa ttaatcgggg tagaaccagc agaatctgct
     1561 attttagaag ggaaagaagc gggacctcac aaaatccaag gaatcggtac aggttttgtt
     1621 cctaaaacac tggatacttc tgtgtatgat aaagtccttt ctattagtgg agacgaagcg
     1681 atggaaacag ctagagaagt tgggcgaaaa gaagggattt tagtaggcat ctcatctggc
     1741 gctgcaattg ctgccgcgct aaaagtcgca aaagaattag gaaaaggcaa gaaggtatta
     1801 gctgtggttc ccgacaatgg tgaacgttat ttatctacag ccctttacca agagatataa
     1861 ggcacttggt ttttctccag ataggtttat gtaaaaaact tttaaagatg aaaagaacac
     1921 acaaaaattt atgatgagaa aaattatttg aatagagacg taaaatagtg aacgcgactg
     1981 ttttacgtct tttttcatta aaatacaata aaattgaatt ttcttttcat gttaagtgga
     2041 ttttaaaatg taaaaatagt atgataagac gagaataaca acgtggggtg tttacatgga
     2101 aaataagtta gtcgaagagg ttatcgaaaa gttaaaaaaa gagaacattc gaatcacacc
     2161 tcaacggtac gcggttttag aatatttgat tgaacatcat tcccatccaa cggctgatga
     2221 gatttataaa gcacttgaac atcggtttcc aaatatgagt gttgcgactg tttacaataa
     2281 ccttcgctta tttacttcga ttggatttgt tcaagaaatg aagtacggcg atgcttctag
     2341 ccgatttgat ttcagttcaa agcgtcatta tcatgtaatt tgtgaaaact gcggtaagat
     2401 tgttgatttt cattacccag ggcttgaaga tatagaaatg gctgcgagca gactgactga
     2461 ttttgagatt aatgaacatc ggttggaatt gtatggactc tgtccggatt gtaaagagtc
     2521 agcaaaaaag gcgcaaatgt aaaaacagtt tctataagtg ttatacctaa aaaaagctag
     2581 ctgtgtaaaa aaacgctagc ttttttattt ttttgtcttt tattcacaat cttagatatc
     2641 aaagtgaata ttatcacaat aagaatcttg tagatattgg gttcttatgc ttgaaaagga
     2701 atgaaactac aaacaaacct ttgtgaattc acaagcatta aactgttgta tccgttttat
     2761 ttctgttata gtagttttgt cgaaggacaa aatgttaatc ggagggacca taaatgaaag
     2821 tagtagtaat tggctgtact catgcaggta ctgcagctgt aaaaagtatt ttaaaaaatc
     2881 atccagaagc agaagtgaca gtatatgaaa gaaatgacaa tatttctttc ttatcttgcg
     2941 gtatcgcact ttatgtcggc ggagtagtaa aggacccagc aggcttgttc tactcaaatc
     3001 ctgaagaatt atcttcatta ggagcaacag ttaaaatgga acacgatgta acagacgtcg
     3061 atacagaaaa taaaacagta acggcaaaag atctgaaaac aggagaaaca gaaacggttt
     3121 cttatgataa attagtgatg acaactggtt catggcctat tatcccaccg attagtggaa
     3181 tcgatgcgaa aaatgtactc ctatgcaaaa actacaatca agcaaatgaa attattgcac
     3241 aagcgaaaga agcaaaacgt gtagtaattg ttggtggtgg atatatcggt attgaattag
     3301 tagaagcttt tgtcgaatct ggaaaacaag tgacattgat tgatggatta gatcgcatct
     3361 tgaataaata tctagataaa ccattcacag atatcttaga aaaagaattg acagaccgcg
     3421 gtgttactct tgcgctaggc gaaaatgtta ctgaatttat cacagatgaa gaaggaaaag
     3481 tgaaacaagt agctacacca acagatacat ttgatacaga tatggtcatt ttatgtgtgg
     3541 gcttccgtcc aaatacaaaa ctgatcgaag gaaaagtaga tacactgcca aacggggcaa
     3601 tcaaagtgaa tgaatacatg cagacaagtg atccagacat ttttgcagct ggagactctg
     3661 cagtagtcaa ctacaatcca agtggcacgc aaaactatat tcctttggca acaaatgccg
     3721 ttcgtcaagg tttacttgtg ggaaataact tgacagatca taaaatggcg tatcgtggta
     3781 ctcaaggaac ttcaggactt tacctatttg gctggacgat cggttcgaca ggtgtgacca
     3841 aagaaagcgc aactttgaac gatctagaag tccaagcgac tgtatttgaa gataattatc
     3901 gtccagagtt catgccaact actgaaaaag taatgatgga gctagtctat gaaaaaggaa
     3961 cgaatcgtat cgtaggtgct cagttcatgt ccaaatacga cattacacaa tcagcaaata
     4021 ccatgtcttt agctgttcaa aataaaatga ctgtagaaga tctcgcactt tcagatttct
     4081 tcttccaacc acattttgac cgcccatgga attacttgaa cctacttgca caagaagcgc
     4141 taggcgaaat cgaaactgca caataaagaa aaagggttgt gacacaattt tgtcacgacc
     4201 ctctgtcttt ttttgtgaaa agtacaatta gttgtctttc ttcgaatttt ttgtcacaat
     4261 aagcagcaaa gataaagctg ttacataaaa gaacaagcag ctttatttga ttttgaaaag
     4321 aaaggtgaga aagaagatga ataaagaata ttttgtccaa caagatgcat ttttagaaga
     4381 ttataaaagt gcttcgaaga aattaacgat caatattgat gagttggcag atcaagtact
     4441 ctctcagttg aatgaaacgc aagaggaata ttacacgatg ccagcaaatg acgccaaaga
     4501 taatgtttct catcgttttc ctttcagtag acgcatctac tcagatgaaa atgacggcac
     4561 attgaataca gagtacacat atgaaggtca gccatatgtg ctagaaactg atgatgatct
     4621 ttaaagacag tttttgaaaa ggccgctcat ccttaagtga tgacaaaaaa tcatcacaat
     4681 taccgatgac tgtctcttta ctatctttta atcagaaaaa ggggttatga caagctttgt
     4741 caaccccttt ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt
     4801 gaataggaaa caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag
     4861 acaactgcta atagaagaat atctggattt agctaatgag attattcatc gtaataaacc
     4921 agaaatggaa aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat
     4981 cgggaaaatc cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg
     5041 agccatcagt aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag
     5101 cgaagagaat aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa
     5161 tagacacgag caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat
     5221 gtcaaaagaa gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg
     5281 aagtagcaaa tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa
     5341 aaatccgaat accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg
     5401 gccgatgacg cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg
     5461 gttatctgag acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc
     5521 gaaaccataa cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa
     5581 tgtgatgaat agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc
     5641 tgaaaatttt ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc
     5701 aatcaaagag aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa
     5761 ttgagaaaag atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa
     5821 taaaggaata acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg
     5881 ggagaaactt aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta
     5941 gccataaacg gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc
     6001 caactcagct aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc
     6061 acccatccat ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc
     6121 atataaggtg gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat
     6181 ccatatcgaa tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat
     6241 aataaggatc ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa
     6301 gaaggcagct agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat
     6361 ggagtgagaa taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa
     6421 tccagtgaat aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta
     6481 catgtaaaaa ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat
     6541 tttgtttcct tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa
     6601 aagtgaagat acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat
     6661 ctgaccgatc agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta
     6721 cgtatactgt gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct
     6781 ggacaaacag tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct
     6841 gaagaatttt tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct
     6901 gatttgcaga tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg
     6961 gatcgtctcg taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa
     7021 gcagatcgat ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa
     7081 gaaaaaaaat acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt
     7141 gaacaagaat ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta
     7201 gaagaagacc attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat
     7261 caggcttata gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta
     7321 cgtacaaaac aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga
     7381 gaagtagaac agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg
     7441 gaggagtagc ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat
     7501 ggaatgtttc ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt
     7561 gcagtgatct taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg
     7621 tttgcctctt ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt
     7681 aaaataaaaa cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag
     7741 cagctgattg aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt
     7801 cctggtgtag gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca
     7861 atcgcagtag atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat
     7921 gctacggtca tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta
     7981 aagacacatc atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag
     8041 tgcgaggtat gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa
     8101 gaaaaggcgc taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat
     8161 gtatgaatta tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa
     8221 agtaaatgta catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa
     8281 taaaagttgt tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata
     8341 cctataaaat aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa
     8401 ggtgtaataa aaatgataag tgataataaa aaaataccat ttataactaa acataaacta
     8461 atggatttgg gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat
     8521 aaaaaagtga gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg
     8581 cttaaaagta cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt
     8641 aataataaac aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat
     8701 aaaaaaagat ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg
     8761 aagccttctt tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca
     8821 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
     8881 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
     8941 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
     9001 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
     9061 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
     9121 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
     9181 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
     9241 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
     9301 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
     9361 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
     9421 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
     9481 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
     9541 ctacgtgtga cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg
     9601 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
     9661 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
     9721 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
     9781 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     9841 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     9901 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     9961 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
    10021 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
    10081 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
    10141 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
    10201 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
    10261 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
    10321 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
    10381 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
    10441 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
    10501 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
    10561 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
    10621 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
    10681 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
    10741 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
    10801 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
    10861 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
    10921 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
    10981 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
    11041 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
    11101 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
    11161 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
    11221 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
    11281 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
    11341 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
    11401 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
    11461 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
    11521 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
    11581 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
    11641 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
    11701 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
    11761 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
    11821 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
    11881 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
    11941 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
    12001 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
    12061 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
    12121 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
    12181 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
    12241 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
    12301 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
    12361 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
    12421 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
    12481 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
    12541 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
    12601 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
    12661 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
    12721 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
    12781 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
    12841 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
    12901 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
    12961 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
    13021 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
    13081 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
    13141 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
    13201 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
    13261 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
    13321 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
    13381 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
    13441 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
    13501 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
    13561 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
    13621 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
    13681 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
    13741 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
    13801 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
    13861 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
    13921 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
    13981 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
    14041 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
    14101 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
    14161 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
    14221 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
    14281 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
    14341 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
    14401 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
    14461 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
    14521 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
    14581 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
    14641 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
    14701 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
    14761 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
    14821 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
    14881 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
    14941 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
    15001 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
    15061 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
    15121 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt
    15181 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
    15241 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
    15301 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
    15361 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
    15421 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
    15481 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
    15541 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
    15601 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
    15661 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
    15721 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
    15781 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
    15841 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
    15901 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
    15961 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
    16021 attttatcgt ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
    16081 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
    16141 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
    16201 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
    16261 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
    16321 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
    16381 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
    16441 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
    16501 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
    16561 tctatagatg ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa
    16621 gtgatcgctg attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat
    16681 cataccaaaa gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac
    16741 cgctttgtga cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa
    16801 aatgagaacg aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag
    16861 gaacagatct cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct
    16921 gaagcggccg aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca
    16981 ttaggagcaa tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt
    17041 tttgatcctg aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg
    17101 acagtgatca atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat
    17161 tacggatatg aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt
    17221 tttctggaat ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac
    17281 aaaaaatgat ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc
    17341 gtaaaagtta cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg
    17401 agtcacaagg aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg
    17461 attcggaatt ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt
    17521 gtcacagtcc ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa
    17581 attaaaaatt gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat
    17641 aaataaatta aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg
    17701 tgttgtattt atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca
    17761 tactatataa gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat
    17821 tctcataatc agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac
    17881 acgatatatg tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt
    17941 ccaaagaact aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat
    18001 acaatacgat cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa
    18061 agatgatcaa tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa
    18121 aagcatgtat tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca
    18181 atggttcgct gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag
    18241 aagcagcaat cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa
    18301 tgacaaaaga agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt
    18361 gccgcttatc cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga
    18421 aaaaagcaaa ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg
    18481 gtgttttctc catggatgga gacattgcac gattgccgga aattattccg attgttgaaa
    18541 aatatggact gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg
    18601 caggaaccgt caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat
    18661 cgaaagctat aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt
    18721 tgaaagctag aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag
    18781 ctgcattggc ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg
    18841 aaaatgctaa ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg
    18901 aaacacctat tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga
    18961 agctgatcga acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga
    19021 caggcaggat cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag
    19081 tagcagttta tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt
    19141 cgtctattta aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta
    19201 gtaaaaaaga tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca
    19261 aattggttca gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc
    19321 gacagatata cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt
    19381 aatggattac gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca
    19441 tttggctgct cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa
    19501 cgtgactggg ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac
    19561 gccaagttca atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac
    19621 tcttcagcgt cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga
    19681 ttattattat gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc
    19741 ttatgcaacc ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc
    19801 aatcaaagaa ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta
    19861 tatgccagat gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt
    19921 tcatcgaaat gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc
    19981 tattcaaaaa atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc
    20041 aatagcagaa tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt
    20101 ttcgccgaaa tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa
    20161 attggtagag acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat
    20221 tggctatggt atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa
    20281 gtaaaaatag aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt
    20341 atgggcacag tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca
    20401 ggatccgcca gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca
    20461 ggactaacag gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat
    20521 atcgaacgga tttacggaaa tacagcagct tttttattgg gctgggcgca agtcgtgatt
    20581 tattttccag caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta
    20641 tttggtcttt cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg
    20701 ttgatcaatt ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc
    20761 aagcttattc ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac
    20821 ttccaactgt ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg
    20881 ggcttgctag caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga
    20941 gaattgaaaa agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc
    21001 atgatcgttt atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc
    21061 gcaggaaaca gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga
    21121 agactggtca cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt
    21181 actggaatgc gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc
    21241 tttgctaaac ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc
    21301 atcgctattg gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt
    21361 gtcatttgga ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa
    21421 cctgatttgt ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc
    21481 attggaggga cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg
    21541 gggatagtat tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta
    21601 aaacattcga attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg
    21661 aggagtacgt ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt
    21721 tgtctacgat gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt
    21781 tactttgatt tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc
    21841 aagcaaccag aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta
    21901 gacaaagcat gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga
    21961 ttgaagacta gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta
    22021 gttctttttc ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca
    22081 aaaacaaagt acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg
    22141 aaagaaatga gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata
    22201 agagagatac aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt
    22261 tgcgctgatt gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga
    22321 atatcgaaag tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt
    22381 ttatttattg tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc
    22441 ccaaatgaca gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga
    22501 caacacggta ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt
    22561 atttttggaa ccagctttta atgttttatt actcatacca tttggcattt atttaagata
    22621 ttatttccgg ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt
    22681 tgaattgacg cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga
    22741 tgtgaatgat ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt
    22801 atttacattt atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa
    22861 gactgtctca ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct
    22921 tattaatttg gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc
    22981 tcatatctgg tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac
    23041 caatggatgg acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga
    23101 acgaatttct ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg
    23161 tttaagctgg ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt
    23221 gcagatgagt gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt
    23281 aaatatcttg ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca
    23341 cacatatact gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag
    23401 caaaaacgct ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc
    23461 acgaatgaat aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc
    23521 aaagggcttc aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg
    23581 aaaaaatatc attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc
    23641 tttgtttgaa aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag
    23701 tagggaacta gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc
    23761 ggagatccgt gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct
    23821 gcatcaccaa cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa
    23881 tgaacaagcg ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac
    23941 attggatatg ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct
    24001 gcagttttta gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata
    24061 catggaaaat ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga
    24121 aaattggctg atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac
    24181 aattggtcat ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat
    24241 tgccgattac ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc
    24301 aagagagaga aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc
    24361 gactgattta gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga
    24421 aattccagaa gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt
    24481 aaaaggaacg gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga
    24541 aaaattgggc gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata
    24601 cgatcgtaat agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat
    24661 tggtcttgtg aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg
    24721 ggcaattgca gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac
    24781 tgctcgtaaa aataagaaaa attcacataa ataaaaaaca agaggttgtg acaaaaggcg
    24841 tgtcacaatc tcttgttttt aagctagact ttttttcatt ccgatacaaa gtacttcatc
    24901 ttcaataaaa ggttctgtgc aagtatgata cccttgtttt tcataaaaat ctacagccgt
    24961 catttcagct actacataac tagtctgaca accttctgaa accgcccgtt tttcagcagc
    25021 ttcaagcaac tgaccgccta acccttttcc tcggtattct tttgctacgc aaaatcgttc
    25081 cggcttgaag caagtaggtg ttttcttttc ataacgcaaa gtagctactg gtcttttttg
    25141 atcaagaaat agataatagg tttgttgcgg gatatctttt ccgtcgaatt ctagttctgc
    25201 aggaatccct tgttctaata caaaaacttg atatctcaaa aagcagctag ctgcgcgtat
    25261 ccattcatcc gctccaacta tttttttcat catattcctc cttgtcatga atagcagaga
    25321 tgtattgatt cctttattct tatcgtacca aaaatcgtgg agtatgacca aaaggaaatg
    25381 aaaataaaaa ttgagatatt gacagtgatc aatagaatgc gtatactaat taagtacgaa
    25441 aaggatatga tttgtttttt aagactcaca gaaaattctt tcttggctga aaaaagaata
    25501 gtcactaatc aaattgctcc ctttttctat tttggtagaa ataccgacgc agctcagcgt
    25561 tatcgagttt aagaggtaat gattacacat cattgcaatc aaggtggtac cgcgagtttt
    25621 cgtccttggc tgtgatggtg tttttttgta tttaatttat agaaagcagg taatgacatg
    25681 aaacaattaa gtagtgcaca agttcgacaa atgtttcttg atttcttcca atctaaagga
    25741 catacgattg aacctagtgc gtctttgatc cccgtgaacg atccaacctt attgtggatc
    25801 aactctggtg ttgcaacatt gaaaaaatat tttgatggtt cagttgtgcc agaaaatcca
    25861 agaatcacaa atgcccaaaa atctattcga acaaatgata tcgaaaatgt cggtaaaaca
    25921 gcacggcacc atacgatgtt tgagatgctg ggtaattttt cgattggtga ctatttcaaa
    25981 aatgaagcca tccactgggc atgggaattt ttgactgatc caaaatggat ggcattcgat
    26041 ccagaaaaac tttatgtaac agtttatcca aaagatacag aagcaaaacg catctggcat
    26101 gaagaagttg gcctgccact agatcacatt attgatgtag aagacaactt ctgggatatc
    26161 ggtgcaggcc catgtggtcc ggatacggaa attttctatg accgtggaga agcttataac
    26221 gatttagcag aagacgatcc tgaaaactat ccaggaggag aaaatgaacg ttatttagaa
    26281 atctggaact tagtattttc agaattcaac cataagcctg ataacacatt tgaaccactt
    26341 cctcataaaa acattgatac ggggatggga ttggaacgca tggtctcaat cgttcaagat
    26401 gcgtcaacga actttgagac agacttgttt atgcctatta tccacgccgt agaaaagcta
    26461 agcaaacaag taaaatatgg tgaaaaccca gtaacagata tttcttacaa agtaatcgca
    26521 gatcatattc gcgccctttc atttgctatt ggcgacggtg cattgccatc gaatgaaggg
    26581 agagggtatg tcttacgccg tttgcttcgt cgtgctgtca tgcatgggaa aaaattaggt
    26641 attgaacaag cattcttata tcgtttagtc cctgttgttg gggaaatcat ggtaagttat
    26701 tatcctgaag tacttcaaca aaaagaattt attgaaaaag ttatccgtac agaagaagaa
    26761 cgtttcaatg aaacaatcaa tgaaggtttg gaaatcttaa atcaagtgat ccaagaagta
    26821 aaaaacgaaa acgggacgac tctagcagga aaagacatct tcaaactata cgacacatat
    26881 ggcttcccgg tagaattaac ggaagaggtg gcagaagatg aaggactgaa agttgatcat
    26941 gctggttttg aaaaagaaat ggatgcacaa cgcgaacgtg ctcgctctgc ccgcagtact
    27001 gaaaaatcaa tgggggtaca atctgcttta ttgacagata tcaaagtaga aagtaaattc
    27061 attggataca cagaacaaga atcagatagt caattattgg tcatcgttaa aggtgagtct
    27121 cttttgaatg aagtcgcaga aggtgaagct caaatgatct ttgatcaaac acctttctat
    27181 gcagaaatgg gtgggcaagt agcggatcaa ggatggatca tgaatgaagt aggcgaaatc
    27241 gtagcagttg ttacagatgt tcaaaaagcg cctaatggtc aatttatgca caccgtagaa
    27301 gtaaaagcac caatgagtga aggacaaacc tatcatctat tgatcgatca atcgatgcgc
    27361 aatcggatca tcaaaaacca tacagcaacc catctactgc acaaggcatt gaaagaagta
    27421 cttggcgagc atgcaaatca agctggttct ttagtcgctc ctggacattt acgattcgac
    27481 tttacccact ttggtcaaat cacttcagat gaattagctg aaatggaaag aatcgtcaac
    27541 gaaaaaatct gggaagctat cccagttgaa acaattgaaa cagatatcga tacagccaaa
    27601 aacatgggtg caatggcttt gtttggtgaa aaatacggac atgacgttcg agtagtaaat
    27661 attggcggct ggtcaatcga actgtgcgga ggcacacatg tagcaaatac agaaaacatc
    27721 ggaatcttca aaatcgtttc tgaatcagga attggtgcag gcgtgcgacg aatcgaggct
    27781 gtaacaagta aagaagcgta cgaactactt gaagaagaag aaaaacaact aaaacaagta
    27841 gcaacaattg ttaaatcacc tcaattgaaa gaagttgttt caaaagcgga acaattgcaa
    27901 cagcaagtaa gagagctaca aaaggaaaat gaacaattag ctagcaagtt agcgaatcaa
    27961 caagctggtg atgtattcaa agatccagaa acgatcaatg gaaaaacaat cattgcagca
    28021 caagtaaaag tgaaagatat gaatcagctg cgtcaattag ctgaccaatg gaaacaaaaa
    28081 aatatttcag atattcttgt tttagcaaac gaacaagaag gaaaagtcag tctgctagcg
    28141 gcaatgacga aagaatcaaa tgaagctgga ctaaaagctg gcgacttgat taaagcaatc
    28201 gcaccgaaag taggcggtgg cggtggtgga cgtccagaca tggcacaagc tggcgggaaa
    28261 aatcctgctg gtattccaga tgcacttaaa gctgcgaaag aatgggttgc gcaacaatag
    28321 ggcgtttacg tttgacagaa aaacaaaagt tcaaacattg aacgaaacat gattatgggg
    28381 gcgaagacaa acaagtcttg ccctcatact tttttcaatt ggatggcgca tctaatcaaa
    28441 tggtcggatt cggatggtct ttagttgacg aaagtgacag aaatttttac gattagtata
    28501 aataaaaagg ggtgaaaaaa tgaatagtag aaataagacc tttcgactag tcttacgtgc
    28561 gatcttgtta gcaatcatca tcgtacaagc gatggttcct tggctggggt ttattccatt
    28621 aggattcatt agtttaacaa ttatccatat cacagtaatt attgctgcag tagtattagg
    28681 cccaaaagat ggcatggtga ttggcttgtt ttggggaatc gctacaattg ttcgtgccta
    28741 tgccatgcca acaacgccat ttgatacatt agtgttcacg aatccgatta tctcggtagt
    28801 tcccagagta cttgttggct tagtagcagg cttggttttc cactggattt atcaaaaaaa
    28861 taaatcaata acgatcagct cagcctttgc aggggtactg ggttcattgg tcaatacagt
    28921 cttagtgtta ggattcatgg gattatttta tacaggtgca acggcagatg cctatggtgt
    28981 agactctgct cttttattta aaaccttagc aggggttgca gcaatcaatg ggataccaga
    29041 agcaataggt gcgggaatca taacaccatt actagcaaaa gcgttatttg cagcaacacc
    29101 gttgaaacca gaataatgac catcttttaa tagtaatagg acgcacgata gatagaaaaa
    29161 ggaagagagg agaggaaaac aatcgtcctc tccatctttt tacctgagca acaagcaaac
    29221 tagaaggggt aaaaaacttg gctaagaaac aagaagaaaa aaagaaacaa ataccgcaac
    29281 agcggacaaa aaaaggagta ctagcgggta tcttaggatt ggttacgaat ctgatcttgt
    29341 ttgtctctaa gctaatgatc gggctttttt caggaagtgt ctccattatg gctgatgcag
    29401 tgaacagtct atcagatact gcttcatcca tattgacttt gatcggattt aaaattgctg
    29461 caaagccagc agatcaggaa catccttatg gacacgaacg cttcgaatat atcagtgggt
    29521 tatttgtttc gatcatcatt acttatgtag gatttcaatt tttagagtct tctgctgaaa
    29581 aaatcatcca tccagaaaat gtctctttaa cacccatcgt cttttttgtc ctaatcattt
    29641 ccatcttttt gaaatttgca caaggcaaaa tgtatcaggt tattgcgcaa tccattgatt
    29701 ctgaaacatt gagagctaca gcaacagata gttataatga tgtctttact acactggctg
    29761 tattgctttc agcagcaatc gaatgggtaa ctggatggcg tattgatgga tatataggtt
    29821 ttgctttagc attatatatc ctttatagtg gattgacgat gcttcgaaat tttgtatacg
    29881 aactattagg aagtcgccca acgccagcag agattgaaga aatggaagag catttaaatg
    29941 cttgcgatga tatacttggc tatcatgatt tattggtgca taactatgga cccaataaac
    30001 gctttgcatc agtccacatc gaagtagatg aatcaatgaa tttgaatgtg gctcataaga
    30061 ttattgatct gatagaaaaa gactttaaaa agtctttgga tgtggaactt gtctgtcact
    30121 tggatccaat gcctgttgat aacgaaaaat actataatat cttgcggcag ttaaagcaaa
    30181 ttcttcttga aacaggtaca gggcttaata ttcatgattt tagagtaatt catcaaggaa
    30241 aaacgctgca atttgatgta gtggtccctg agaaattcca gtttgttgat acagaactag
    30301 aaagaatctt acgtagtcaa atagaagaaa aaatcggaga ttaccaattg gaaattacgt
    30361 ttgatcacaa ttatctttta tattaaatga gaaactataa aaagactcct taaagttttt
    30421 aatttaaaga gtcttttttt cttttaattg tttatggaga gcctgacgtg caagattatc
    30481 tgctccttta tttttgtttt cgggcaacca ttgcaggatc aataaagaaa attcggatag
    30541 aagttcttgg attctttgaa ggtagggaag gaagagctcg ttcttcgttg cgtttttgtc
    30601 gaccgtagaa actagtgttt tgctgtctga aaaacagaaa atcgtttcat tctgtaagtc
    30661 gtttttcttt agaaattcta aagtttttaa aaagacttcg aactctgctt gatggtttgt
    30721 ccctatagaa agcgggatag atagctgttc ttgtttacct tgatagacaa tcaagattcc
    30781 acctccacta ggaccagggt tgccttttgt agaggcatca atgtatactt ttaacataaa
    30841 aagagattct cctttttgtt caaactaatg ttatggtaag attatatcat tactgaatcg
    30901 gtgagaggtt agagaatgaa aaaaaatatt cgatggcagc ctgaactggc acatacgatc
    30961 atctattggt cattgacctt gatcattctg ttttttagtc tgattctttc tttagaaaac
    31021 acaggtcctt attggaaaag caattttgtt ttaggtattt ttcttgtttt tctatttcta
    31081 ggtttgcggc gttcttttat tttaaaatca aactctgtga ttatacgtta tgctgctttt
    31141 tggaaagacc gagaaatatc tgtcggacag attcgatctt tgacgccaac taatactggg
    31201 gtgcaaatga tgttgcaaga tgagaaagcc ccatctgttt tcatgatgcg aaaaaaagat
    31261 caagtagtcc tttttgatca ttttgaaaaa aacggaccca aatcagaatc aattccttat
    31321 ccttatacga aaaaaagaaa aagctaattt taaaaatcag aacctaaaaa aacgaatttt
    31381 tacaggaaaa gaaaagagtg agacgtacgg ttcatcccgt ttagcgtctc actctatttg
    31441 tttatctatt catgcatact agtatcggta gtctgaacgt tgcctttctt gacatgggca
    31501 gcttgtgttc ctcgattccc ttcgatgatc tcaaattcga ccacttgatt ttcttccaaa
    31561 gttttgaatc cctcttcttc aatcgcagta aaatgtacaa aaatttcttc tgtgtcatca
    31621 taactgataa agccgtatcc ttttttgttg tcaaaccatt ttacaattcc tgtggtcaaa
    31681 gcactcacga cctttctaaa gtctgatcat agccttcatt ataaagagta tttataagta
    31741 cgtcaaataa attaaaaacc tgtaatttta tgtttttttt ctgaataaaa aaaggtataa
    31801 ttggcatatc ttaacaaaga agatattttg ttgaataaag ttcgtgaaaa ggggtaatca
    31861 aatgaagaat gatctgcaaa tttcacaaga aacagagcta gaaccgattg ttgaagtggc
    31921 tagtaaatta gatcttaagg aagacgattt ggaactgtat gggaaatata aggcgaaaat
    31981 caatttttct ggaatcaatc gatcaaagga taacgctgag gggcatttga tcttagttac
    32041 ttccatcaat ccaacaccag ctggcgaagg aaagtcaacg atcactgtag ggttaggaga
    32101 cgcgctcaat aaaatcaata aaaaatctgt tattgcattg cgagaaccct cacttggtcc
    32161 tgtgatggga atcaaaggtg gtgctgcagg cggaggatat gcacaggtat tgcctatgga
    32221 agatatcaac ttgcatttta ctggtgacat gcatgctatc acaacagcta ataatgcatt
    32281 atctgctctt ttagataatc atattcatca aggaaatgaa ttgaacatcg atgcccgccg
    32341 agtgatttgg aaacgggtag tcgatctcaa tgatcgtgaa ctgcgtaaag taattgttgg
    32401 cttgggtggg ccaatccaag gtgttccaag agaagatggg tttgatatca cagttgccag
    32461 cgaaatcatg gctatcttgt gtcttgcggc agaccttgaa gatttaaagg ctcgtcttgc
    32521 aaggatcgtt gtcggctata catttgaccg tcagcctgtg actgctggag acttgaaagc
    32581 agaaggcgct ctggcattac tgctgaaaga tgcaatcaag ccgaatcttg tacaaacaat
    32641 ttacggaaca ccagcttttg tccacggggg accgtttgcc aatatcgctc atggctgcaa
    32701 tagtatttta gctaccaaga cagcattgag attagcagat tacgttgtca cagaggcagg
    32761 atttggtgca gatcttggcg gagagaaatt tttagatatc aaagtaccta acttgaaaaa
    32821 agcgccggat gctgtggtga ttgtcgccac tgtccgtgca ttgaaaatgc atggcggaat
    32881 gaaaaaagat gaacttaaaa atgagaatct tgatgctttg aaagtaggtt ttgcaaattt
    32941 aaagcgccat atacgtaata tggaacaata tcagctacct gtgatcgtcg caatcaatga
    33001 attcgtaaca gatacagaca atgaactcac actgttggag cacttgtgtg aaaatcaggg
    33061 gattcttgcc aagagagcga gtgtatgggc agatggagca gaaggcggcg ttgatttagc
    33121 aaaagctgta gtacgattga ttgatagaaa agaagctaat tacaagccat tataccgcct
    33181 agaagaaacg atacaagaaa agacagaaac aatcgtcaag aaaatttacg gaggaaatgg
    33241 tgttgttttc agcaaaaaag cgcaaaaaca aatagaagag tttacgaaga atggatggga
    33301 caaactgccg atttgtatgg caaaaacaca gtattcattt tctgatgatc cttcactgct
    33361 aggtgcaccg gaagatttca ccatcacgat ccgcgaaatc atcccaaaat taggggcagg
    33421 atttttagta gccttgactg gagatgttat gacgatgcct ggtttgccta aaaaacctgc
    33481 tgcattgaat atggacgtga caaatgacgg agaagtgttg ggattgtttt aagcttgatt
    33541 ataatctacc atcgaaggag ctgtattttg actacagctt ctttttttag acgataggga
    33601 attaattttg tttacactag gatcattctt tttctttatt gtattttgag ctatactaaa
    33661 gcataatagg agggtatgat gaaaacgaca tttataagaa aaaccggttt ttacggtatg
    33721 ggtagctcga ttcagctaag aatcaacaat gaaaaacgca gtgttctcag tcatgaacaa
    33781 aagataacgc ttgatctgga agtgcccttt acgatgcagg tcacctttta ttggctaaaa
    33841 agccccgttt atacagtgaa agaagcaaag cctgcttatg tgatcacaat gaattacttg
    33901 attcttcaaa tctatccgtt tttatttcta gcaactgggt tgggggccgt tttcctacaa
    33961 aatttatttt tcagtttttt tgcagttatt gtgttgattg cgttcttttt ctatataaaa
    34021 aaccgggcat atttgatcaa ggaggaaaat tatggcaaac tctgatcttt ttttaatcag
    34081 tttcaatcga atcgaaaaat ggatgagaga cgagatggga aatgcacgaa atatgggatt
    34141 taccgaactt gtcagacgcc tagctcaaag aaaacaatta atgatcagaa aatacgaaga
    34201 tgatctttta cagcttgctc agttaaggaa tgcgatcgtc catgatcgga tcgcagtcga
    34261 ttttgtcatt gcagagccaa atgattggac agtcaagcga atccagctga tcgaacaaga
    34321 actgattcag cctgaaaccg tgctgcctcg atttgcaaaa cgtgtaacag gttttgaaca
    34381 agatcttccg ttacttgaac tgttaaagat agtagcagaa aaaaggtatt cacaatttcc
    34441 gttatacaat aaaggaaaat ttgtagcatt gattacttta cgtaatatcg ggttttggct
    34501 agcaaaagaa agccaaaaag gtccggttga tttaacaaat aaacgagcgt tggatttgat
    34561 catccaaaac ggaaagtaca caaattatca ttttgttcca gctaaaacac atatttacga
    34621 ggttgaagcg atgtttcgtg agcaagggac tttggaagcc gtacttatca ctaaagatgg
    34681 gaatcccgat ggtaatctgc tcgggatcgt acgacctcgt gatatttata aacaaataga
    34741 aaaggattga ttttttgtta attatttatt ggatattcag cgctttgcta gtaggagtgg
    34801 atcagttggt caaatggtgg atcactgata atctagcgct tggagagacg aaaaatctta
    34861 taccaggtat tttgtcactg aatcatattc gaaacactgg agccgcatgg agtatgctag
    34921 aagggaagat gtggttcttt actatagtga cactcattgc agtcgttgtg attctcacat
    34981 tgatgattaa aaatcgtgaa aaaggtaatc gctggttcat gattggattg agtttgattc
    35041 tagctggtgc gattggcaat tttatcgacc gtattcgtct tggctatgta gtagatatgt
    35101 tccagacaga ttttatgagc tttccgattt ttaacgtagc agatgtgaca cttgtatgtg
    35161 gagtgatttg tatgttaatt tatattattt tagatgaaaa ggatcaaaga aaaaaatgac
    35221 agaacttaaa acgacgattc accatgaatc tggtaggatc gataaagtat tgactaattt
    35281 attcaccgat tacagtcgtt cgcaaattca gctgtggctg aaaaatggag cggtttctgt
    35341 caatggacag ccagtcaaag caaattacaa agtaaaacaa ggagacgaga ttactgtctt
    35401 gatccccgaa ccagaaacat tagatgtggt cccagaaaat atcccgttga cgatcgttta
    35461 cgaagatgaa gatgtagcgg tgataaacaa acctcaagga atggtcgttc atccttcagc
    35521 aggtcatacg catggcacaa tggtcaatgc gctgatgtac catatcaagg atctttctac
    35581 gatcaacggc gttattcgtc caggtattgt tcaccgaatc gacaaagata cttccggact
    35641 gctaatggtt gccaaaaatg accaggcaca cgaatcatta gctcagcaat taaaagataa
    35701 gacctctttg cgcaaatatg ttgctttagt ccatggagag attcctcacg aaaaaggaac
    35761 catcaatgcg ccaatcggcc gttcgaagga aaaccggaaa atgcaggcga taagagaaga
    35821 tgggaagtcg gctgtcacac attttactgt attggaacgt ttcgaaggat ttactctggt
    35881 tgaattaaaa ctagaaaccg gaagaacaca ccagatccgt gtgcatatga agtatatcgg
    35941 ttatccgtta gctggagatc cagtatacgg accgaagaaa actttgaaag gcaatggtca
    36001 gtttctccat gcgcaaatgt taggttttac gcacccgact acaaacgaaa agatgatctt
    36061 tgaagcacct cttccagaag tttttgaaaa aactttagaa aaattaagaa aaaacattgc
    36121 attttaattt agataacggt atagtaatta acaacgaaag cataaaactt aatagaattc
    36181 ctttaagttt agtcccgtga ggctaagaag ggtgggagca aggatacgta tggtgcgcca
    36241 taagtagatt gctcattgac atagtatagc tatcagtgta tcagtatacg ctcagtctaa
    36301 acattcctcc tgtcctctta gggcaggagt ttttttatgc aaaaaagtag ggggaatgaa
    36361 aatgcaagca aaagaagtag tagatcaggt aaccatgaag cgagcattga ctcgaattac
    36421 ttatgagatt atcgagagaa accatagtat ccaagatatc gtattggtag gtatcaaaac
    36481 acgaggaatc tacattgcat caagaattgc cgaacgcctg aagcagctag aagatatcga
    36541 tattcctgta ggagaactgg atatcacttt ataccgagat gacaaaaaag aaaatccaga
    36601 agaaccggaa cttcattctt ctgacatccc agtttcctta gaaggaaaag aagttatttt
    36661 gattgatgat gttttgtata caggacgaac gattcgagca gcaatggacg cagtaatgga
    36721 ttttggcaga ccaagaaaaa tttcattagc agtcctggtc gatcgtgggc atcgagaatt
    36781 gccaatccgt gcagattatg ttgggaagaa cattccaaca tctcgggcgg aagagatttt
    36841 agtagagatg caagagcttg atggacaaga tcgcatcatg attttgaaag aggaagatta
    36901 gaggagagag aaacatgtcg gagaaaaaag gatttcataa tgatgacgtg gtgttagata
    36961 tccacgatcg cccaacccca ggacattggg taggattaag tttacaacac ttgttcacga
    37021 tgttcggagc aaccgtgtta gtccccatct tagtaggtat cgatccaggt attgcgctag
    37081 tcagttcagg actaggtaca ttggtgtact tatttactac taaaggaaag atacctgcgt
    37141 acttaggaag cagcttcgct ttcattgcag cgatgcagct tttgatgaaa acagatggtt
    37201 atccagcgat tgcacaagga gcagtcacaa ctggattagt ctatttgatt gttgcgctga
    37261 tcatcaaaaa gatcggttca gcatggctgg ataaaatctt gcctccaatc gtcgtcggtc
    37321 cagtcatcat ggttatcggg ttgggacttg cggcaaatgc agcaacaaat gctatgtata
    37381 atcagggcac gtatgatttc aagtatattg ctgtagcgct gatcacatta ggattaacaa
    37441 ttttcttcaa catgtggcta agaggttttc tcggattgat tccgatttta ctaggtatta
    37501 ttagcggata catcgtagcc ttgctgtttg gaatcgtgga tactaagcca atcgtagacg
    37561 ctgcctggtt tgctgttcct aactttgaga ttccctttgt acaatatgaa ccaaagctat
    37621 atcttggagc aatcacaaca atggcaccca tcgcttttgt gacgatgaca gagcatatcg
    37681 gccatcttat ggtattgaat aaactaacta aacgtaattt ctttgaagaa ccgggtcttc
    37741 ataagacgtt gacaggtgat ggattagcac aaatcgtggc agcctttgtc ggaggtcctc
    37801 ctgtaacaag ttacggtgaa aacattggtg ttctggctat cacacgtgtc catagcgtgt
    37861 ttgtgatcgg tggagctgca gtatttgcag tcattttagg attcgtagga aaattaagcg
    37921 ctttgatttt aagtatccct ggaccagtca tctcaggaat cagttttatc ttatttggag
    37981 taattgccgc aagtggaatg aagattttaa tcgagaacaa aatcgatttt gataaaaaga
    38041 aaaatctgtt gattgcttca gttatcttag tagtaggaat tggcggactc gtctttgaag
    38101 taggcacatt tacattgtcg gcaatggcat tagcaactgt acttggcatc attttaaatc
    38161 ttatcttacc agaaacttca cgaagcgaag aaaactaagg aggaaacatt atgatcatca
    38221 aatcagaacg tatcagctta aagcatttat tgaccgttga ggcacttact gatcaagaag
    38281 ttatgggctt gatccgcaga gggcaggaat tcaagcaagg tgctaattgg actccgcaaa
    38341 agcgccagta ctttgctaca aacctctttt tcgaaaatag tactcgcaca cataaaagct
    38401 tcgatgtagc ggagaaaaaa ctagggctag aagtgattga atttgaagca agcacaagct
    38461 ctgtccaaaa aggggaaaca ctatacgata cagtactgac gatgtcagca ttaggcgtag
    38521 acgtagcggt tatccgtcat ggtgatgaga actattatga cgaactgata caaagtaaaa
    38581 caatccagtg ttcgattatc aatggaggag acggaagcgg acagcatcca acccaatgct
    38641 tgcttgattt gatgaccatt tatgaagaat ttggtcattt tgaaggtctg aaagttgcca
    38701 tcgtaggtga tatcactcac tctcgcgtag ctaaatccaa tatgcagatg ttaaaacgtc
    38761 taggcgcaca agtattcttc tcaggtccta gagaatggta cgacgatgaa ttcgaagtgt
    38821 acggacatta tatgccattg gatgaactac tagatcaagt tgatgtcatg atgatgcttc
    38881 gggtgcaaca cgaacgccat gatggaaaag aaagtttctc aaaagaaggc taccatcagg
    38941 aacatgggtt aacagttgag cgtgcgaaga agttgcaaaa acatgcaatc attatgcacc
    39001 cagcaccagt taaccgtgat gtagaattag ctgattcatt agtggaagga ttacagtcgc
    39061 ggatcgttca gcaaatgagc aatggagtat tcgtcagaat ggcaatctta gaagcagtgc
    39121 taaatggaaa agcgtaatta taggaggatg aaaaaatgaa aacactcatt aaaaacggtc
    39181 agatcaatac acgaaaaaat atgacgacac cagcagaaat ttggatagaa gatgggcgaa
    39241 tcaaagcaat cggtacagga ttctcagaag ccgaatttga tgaagtgttt gatgcaaagg
    39301 gacaattgat cacacctggt ttagtggacg tccatgttca tttgagagag ccaggattta
    39361 catacaagga gacgatcgaa gctgggactc gctcagctgc tcgtggcggt ttcactactg
    39421 tatgcgcgat gccgaattta aatcctgtac ctgatacggc agaaaagctg agacaagtat
    39481 atgacatcat tagaaaagat gcagttgtga aggtattgca gtatgcgcca atcacagaaa
    39541 atctgcgaag tgagaaatta gttgatcaag aagcactgat tgaagaaggt gcttttgctt
    39601 tcacaaatga cggtgtaggt gtccaaacag ctgggacgat gtatctggct atgaaagaag
    39661 ctgcaaaaaa caataaagcc ctagtagccc atacagaaga tgaatcttta ttatttggcg
    39721 gcgttatgca cgctggcaag aaggcagaag aacttggtct tcccgggatc ttaagcgtaa
    39781 ccgagtcttc tcaaattgct agagatctgt tgctagctga agcaactggt gttcattacc
    39841 atgtttgcca tgtttctact aaagaaagtg tccgtgtaat cagagacgca aaaaaagcag
    39901 gaatccacgt aacagcagaa gtttcacccc atcatcttat tttgatcgac gaagatattc
    39961 ccgaagattt cggcttttgg aaaatgaacc cgccgctaag aggacgggag gacagagaag
    40021 ctttgatcga aggcttgctt gacggtacga tcgattgcat cgctacagac catgcccccc
    40081 atggattaga agaaaaaagc caaagtttca tgaaatcacc atttggtatc gtaggaagcg
    40141 aaacagcgtt tcaactgatc tatactcatt ttgtagaaac tggtcgattc acgttggaac
    40201 aagtgatcaa ttggttggca gttaaaccgg ctgagatttt tggtttgaat gcaggaacgc
    40261 taacggttgg tgcccccgct gatgtagcag tttttgatat tacacaaact tgcacgatcg
    40321 ataaagaaga ctttttatca aaaggggaga atacaccttt tatcggctgg aaagtaaaag
    40381 gcgaaacaca aatgactttt gtcaacggaa aacttgtgtg gcagaaggga gaataaaagt
    40441 atggaacgtt tgcttatatt agaagatgga acagttttcg aaggaaaggc ttttggtgca
    40501 gatgctagtg tcttcggaga aatcgttttt acaacaagta tgactggtta tcaagaaact
    40561 atcactgatc aaagttttaa cggtcaaatc attacattta cctatcctat ggtgggtaat
    40621 tatggggtaa atagagatga ttatgaatcg atttctccaa catgcaaagg agtagtagta
    40681 aaagaacatg cacgtgtagc ttcaaactgg cgaaaccaaa tgacgctaga ttcatttttg
    40741 aaacaaaaag gaattcctgg aatatcaggt atcgatacgc gcgcccttac tcgcaaaatc
    40801 cgtgaagtcg gaacgatgaa agctagtata gttgatgctg gagattcctt cgaacatgca
    40861 tttgatcagc tgaaagcaac cgttctagca accaatcaag tgcagcaagt ctcaactaac
    40921 aaaccttatc caagtccagg aacaggtcgg aaagtcattg tcattgactt cggcttgaaa
    40981 catagtattt tacgagaatt gagtaaaaga aactgtaacc tcacagtact tccctataac
    41041 acagatgccg agacgatttt agcgctatca ccagacggag tcatgctgac gaatggacct
    41101 ggtgatccaa aagatgtgcc agaagcaatc gaaatgatca aaaaaatcca aggaaaagta
    41161 ccgatttttg gtatttgtct cggtcaccag ttatttgctt tagccaacgg tgcagatacc
    41221 tataaaatga aattcggaca tcgaggatta aatcacccgg tacgagaagt agcgaccgga
    41281 agaattgatt ttacttctca aaatcatggc tatgcagtcg atgaagccac gattgatcca
    41341 gaaaaactca tcgtaactca tgtagaagta aatgacggaa cagtagaagg agtcaaacac
    41401 agagattatc ccgctttcag tgtgcagttt catccagatg ctgcccctgg tccgcatgat
    41461 gcactacatt tatttgatga atttatggaa atgatggacg caggaaagga gcagtaaaca
    41521 gatgccgaaa cgtacagata tcaagaaaat tatggtgatt ggatctggtc cgatcatcat
    41581 tggtcaagcc gcagaatttg actacgcagg aacacaagcc tgccttgcct taaaagaaga
    41641 aggatatgaa gtggttttag taaattctaa tcctgcgacg atcatgacgg ataaagaagt
    41701 ggcagatcaa gtatatatcg aaccgatcac acttgaattt gtatcaagga ttcttcgaaa
    41761 agagcgtcca gatgctctcc ttccaacttt aggcggacag acaggcctca atatggcaat
    41821 ggagctggca gcatcaggta ttttagaaga attgaacata gaacttctag gaacaaagct
    41881 ttctgcgatc gatcaagcag aagatcgtga tctattcaaa cagttgatga aagaattgaa
    41941 tcagccaatc cccgagtctg aaatcgtcaa tacagtagaa gaagctgtag attttgcaaa
    42001 taaaatcggc tatcctgtca tcgttcgtcc agcctttact ttaggcggaa ctggtggagg
    42061 tatgtgtgaa aatgaagaag aattacgtat cgtatcagaa aatggattaa gtctttcccc
    42121 cgctacccaa tgtttgattg aacgaagtat tgcaggtttt aaagaaattg aatatgaagt
    42181 gatgagagat tcggctgata atgcaatcgt tgtctgcaat atggaaaatt ttgacccggt
    42241 gggtatccat acaggtgatt ctatcgtatt tgcccctagt caaacattgt ctgaccatga
    42301 atatcaaatg cttcgtgatg cttctctttc gattattcga gcacttaaga tcgagggagg
    42361 ctgtaatgtc caactcgctc ttgatccaca tagttttaat tattatgtga ttgaagtcaa
    42421 tccgcgtgtt tctcgttcat ctgcgttagc aagtaaggcg actggctatc cgatcgctaa
    42481 gctagctgct aaaatagcgc ttggattaac attagacgaa atgaaaaatc ctgttacagg
    42541 aacgactttt gcagaatttg aacctgcatt agattatgtt gtagctaaaa ttcctcgctg
    42601 gccgtttgat aagtttgaaa acggagaacg gcttttaggc acgcagatga aagcaactgg
    42661 tgaagtgatg gctatcggtc ggaatatcga agagtcttta ttgaaagctg tgcgttcttt
    42721 agaaatcggt acacaccata tcgaacttcc tgagttggca gacatcacgg acgatgacct
    42781 aatccaaaaa gtggttcgag cacaagatga tcgcctgttt tatgtagctg aagctattag
    42841 aagagggtac accatagaag aattagcgga tttgacaaaa atcgatttat tctttttaga
    42901 taaactgttg catatcgtag aaatcgaaca gcagttgaaa cagcagccgt tggatgacaa
    42961 gatattgaaa acagcgaaac aaaacggttt tacagacaaa aaagtggcgg agctgtggga
    43021 aataaacgaa gaagccgttc gccagatgag aaaagaaaat gatttgattc ctgtatataa
    43081 gatggttgac acttgtgcag cggaattcga atcaaaaaca ccttattttt atagttccta
    43141 tgaatatgaa aatgaaagtt cacgatcaga aaagccctca attctagtac tgggatctgg
    43201 tcctatccgt atcggacaag gggttgaatt tgactatgcg actgtgcatt ctgtcaaagc
    43261 aatccagcag gcaggatacg aagcaatcat catgaacagc aatcctgaaa cagtttcgac
    43321 tgacttttct atttcggata aattatattt tgagccattg accttcgaag atgtgatgaa
    43381 tgtgatcgag ctagaacagc cgataggagt aatcgttcaa tttggtggtc agacagcaat
    43441 caacttagcc gaacctttga ctgctgctgg tgtaaaaatc ttagggacaa cgatcgaaga
    43501 cttggatcgt gcggaaaatc gtgatttatt cgagcaagcg ctgaaagagt tggatattcc
    43561 tcaaccttta ggggatactg ctacaagtaa agaagaagcc gtggttatcg cttcgagaat
    43621 tggttatcca gttcttgttc gtccaagcta tgtattaggc ggacgtgcga tggaaatcgt
    43681 tgaaaaccag cgagatttag aagattacat ggaacatgct gtgaaagcat ctccagaaca
    43741 tccagtacta gtggaccgtt acttgcttgg tggtgaatgc gaagtggatg cgatttgtga
    43801 cggtgaaaca gtactcatcc cagggatcat ggagcatatt gagcgtgctg gtgtccattc
    43861 aggggattca atggctgtgt atccacctca aacattatct gaatcgatca agaaaacgat
    43921 cgaagattac acgatccgct tagcattagg tttgaattgt gtcgggatga tgaatatcca
    43981 gtttgtcatc catgaaaatg aggtttatgt gatcgaagtc aatcctcgag caagtcggac
    44041 tgttccattc ttaagtaagg tgacaggaat tccaatggca caaattgcga cgaaagctat
    44101 tttgggagag aaactaaaga cacttggtta tgaaaacgga ctttatccag aaacaaaaga
    44161 agttcatgtt aaagcacctg tcttttcttt tacgaaattg cagaaagttg atacttactt
    44221 agggcctgaa atgaaatcga ctggagaagt aatgggatct gacagacaat tagacaaagc
    44281 tttgtacaag gcattcgaag cttctggatt acacttgcct gaatatggag ccgtattatt
    44341 tacgattgcg gacgaaacaa aagaagaagc actagaatta gctaaacgtt ttacagaaat
    44401 tggctatagt ctgataggaa cgaaacatac agctgcttat ttcgaaaaaa atggtctggt
    44461 cgttgaaaca gtagcgaaaa tttctgagga agcagcagaa aaaaatgtag tcgacttaat
    44521 aagagatggt aaaacacaag tggttgtcaa tacgattgat aaagatcggg gaaatgcttc
    44581 taaagacggt ttcatcatcc gaagagaagc agttgaacat ggtattccat tgtttacttc
    44641 tttagacaca gcagatgcga tcgttcgagt gatggaatcc cgtgcttttt caactaaccc
    44701 tatttaacgg cgagcacatg ttaagacaaa aagacgaaaa accgttgcag gaggggacag
    44761 atgaaacaag aaatgatgga aatcgttcag caaaaacagc tggcaccaaa gatttttgaa
    44821 atgacattga aaggtgatct agtaaaagaa atgcagcaac caggacagtt cttgcatatt
    44881 ctcgtgccgc gtgcagactt gctattacgc cgaccgatta gcttgaatca tatcgaccac
    44941 gaaacaaata cttgccgtat catttatcgg gtggaaggtg aggggactag agtcttctct
    45001 actctttctg ccggagacca tttagatgtc atgggtcctt taggcaatgg ttttgatttg
    45061 tccaatcttc atacaggaga cgaagtattt ataatcggtg gaggaatcgg tgtccctcct
    45121 ctatatgagt tatcaaaaca gttagtcgaa aaaggaatta agccaacgca ttttttaggt
    45181 tttgccacac atgaagtcgt ttattatgaa aaagaattta atcgtctagg agaaacaaga
    45241 atcgctactg acgatggaac atacggtatg cacggaaatg tcggtaattt attgttagga
    45301 acgaagacgg aacctacagc tgtttttgca tgtggttcaa acgggttatt gaagacagtg
    45361 gaacagctgt tttcttcgca tcaaaatgtc cagttatcat tagaatcccg catggcatgt
    45421 gggatagggg cttgctatgc ttgcgtttgt catacgccgg aagatgaaac aggaacaaaa
    45481 agtgtgaaag tttgtgacga aggaccgatt tttaaaatag gagaggtaat tatatgaatg
    45541 agaatccttt agcggtcaaa cttcctggcc tagaattaaa aaatcctatc atgccggcaa
    45601 gcggctgttt cggttttggc aaagaatacg gaaaatacta tgatttgaat cagcttggat
    45661 cgatcatggt caaggcaacg actccaaatg cccgctttgg caatcccacg ccaagagtgg
    45721 cggaaacacc atctggcatg ttgaatgcaa ttggtttgca aaatcctggt ctagacgttg
    45781 ttatgcataa acttcttcca gaattagagg agtacaatga gttacccatc atcgcaaatg
    45841 ttgctggtgc ttgtgaagaa gactatgtag aagtttgtag caaaattggc gaagcaccaa
    45901 atgtgaaagc aatcgagctg aacatttctt gcccaaatgt caaacatggc ggaattgctt
    45961 ttggaacaga ttctgatgtt gcttttcaat taacacaagc agtaaagaaa gtttcttctg
    46021 ttcctgtcta tgtcaaattg tccccaaatg taacagacat cgttccaatc gctcaggcaa
    46081 tcgaagctgg aggggcagat gggtttacga tgatcaatac tcttcttggt atgcggattg
    46141 accttaagac aagaaaaccg attttagcca atcaaacagg tggactctcc ggaccagcaa
    46201 tcaagcctgt cgctattcgt ttgattcacc aagtagcaag tatatccagc cttccaatca
    46261 ttgggatggg cggcgtgcag acagtggatg atgttcttga gatgtttatg gctggagcaa
    46321 gtgctgtagc tatagggacc gcgaatttca ccgatccgta tatctgtcct aaactaatta
    46381 aagagctccc tgtgcgaatg agcgaactag gcatcgaatc gctggaaaga ttaatcaaag
    46441 aagtgagaga ggaacgtgaa cgatgaatca actagaccaa cgaccaatta ttgcattaga
    46501 tttttcaact aggcaagagg tagaagactt tcttcgattt ttcccgaaag aagaaaaatt
    46561 gtttgtgaaa atcggaatgg aattgttcta ccaagaagga cctgaaatcg tacgttatct
    46621 aaaagaggct ggtcataatg tatttttaga tctgaaactt cacgatattc cgaatacggt
    46681 cgaaaaagca atgcggggat tggcaaagct tggtgttgat ctcacctgtg ttcatgccgc
    46741 tggcggtatt cgtatgatgg aggcggcaat gcgaggatta gaagagggga ctccagaagg
    46801 tggaaaacgt ccgctacttc tagctatcac tcagcttact tctacaagtg aagaagaaat
    46861 gcatgccgat caactaatcg aagtttcttt agaaaaaagt gtgatccatt atgctagctg
    46921 tgccaaaaaa gcaggattag atggtgtggt ttcttctgct tgggaagtag aagcgatcaa
    46981 agaaatggca ggagacgaat ttgtttgctt aactccgggt ataagaccag aaggaacagt
    47041 cgcaggagat cagacaagag tagtcacacc ttctcaggca aaaaagatcg gctcaacttt
    47101 tatcgttata ggtcgaccaa tcactcagtc aactaatcct tataaagcat atcaaacgat
    47161 tcaaacagaa tggagctaac ctaaaatgaa tgttgaacaa agtatcgcaa aagacttatt
    47221 agaaattgaa gcagtatttt taaatccaag taatcctttt acatgggcaa gtggaatcaa
    47281 aagcccaatt tactgtgata accgaatcac gatgagctat ccaaaagtcc gaaaagagat
    47341 cgcaaaagga ttagcaagca aaatcaaaga agcttaccct gaagtacaag tgattgctgg
    47401 aactgcaaca gcaggaatcc ctcatgccgc atgggtagcg gaaatactgg atttgccaat
    47461 ggtctatatt cgaagtaagg cgaaagatca tgggaaaggt aaccaaatcg aaggacgtat
    47521 atttgaaggt cagaagatgg ttgtgatcga ggatttgatt tctacaggcg gaagtgtctt
    47581 ggaagcagct gaagcagcaa aaagagaagg tgcggatatc cttggtgttg cggctatctt
    47641 tacgtatgag ttgccaaaag gaaaagcaaa tttcgaaaaa gccgaaatcc ctcttatgac
    47701 gttgaccaat tattctgtat tgattgaagc agctttagaa gatcgttata tcgatgagca
    47761 agaattaact ctgctaaaag aatggaaaaa agatcctgaa aattggcaga tttaagcgcg
    47821 cttgatgaag atagagaaat ccgatttgtg tctccagaat catcaattgg aatagcaaaa
    47881 atccaaaaac tgattgcgag aagcatcttt tcatcaggta tgaaaagaaa cttctatcgt
    47941 gatcagtttt tgattttttt aaaattcatt tttctaagac tggttagcag aaagaagaga
    48001 ataatctctt ctcttttttc tattatatat agattttctc tattttttgg taagggagct
    48061 gtttcaaaaa tggtaaagag cggaaatgtt gcgaatatca gttatttaat gatatgatat
    48121 tcggaaaaag aaatctcaaa gggaggtaac ttttatgggg ttgaatgaat ttattttagg
    48181 attgaacaat ttagagacga tcacaagggc acctggattt tttaaatata cagagcatac
    48241 agttgcagca cattcgtatc gtgtagcatc tattgcgcaa gttctaggag acattgaaga
    48301 agcgaatgga caaccgatcg attggaaact gctctatgaa aaatcattga atcatgacta
    48361 cacagagcgt tttattggtg atatcaaaac gccggtgaaa tacgcaagca aagagttaag
    48421 agggatgctg caaacagttg aagaaaagat gacggacgaa ttcatcaacc aagagattcc
    48481 agctgagttc caagaagttt atcgccgtcg gttgttcgaa ggaaaagatg aaaccgtaga
    48541 aggagaacta ttagccattt cagataaggt tgaccttctt tatgaatctt ttgatgaaat
    48601 catcaaaaat aacccggaaa aagtttataa ggagatgttc attgaggcag tgactacgat
    48661 taaaagcttt gaacatcggc cttctgttca gtatttcttt aaagagatat ttccggaact
    48721 attgaaccag gaattttatg gaaaagaggc gtttttagaa accgtctcaa cgattgtaaa
    48781 gaaagaagaa aaataaaaat gatatgagat gcagggggaa gtatagttga aaaagaatat
    48841 ggatgtcgaa tggggctatt ctggagacaa aggtccggaa aattgggcga gtttatgtga
    48901 ttggtttgcg agaggtgcgg aatttccatt gcagtcgcct attcatttga ccaaggggga
    48961 agaaaccaaa atagaaggag acacgctttc ctttcattat caaaagcaac ggtttactga
    49021 caaggaattc aaaaacacga ttcatttagt accttttgac caactcagtt atgtagagtt
    49081 caagaaagaa cgctattatt tgacagatat tcatttccac ttgccttctg aacatatcat
    49141 caacggaaaa caggaagata ttgaatttca ttttgttcat atgaacagca aaaaagagaa
    49201 tctagttgtg ggtgtcatgt accagctaat ggtacaggaa ggttggctgt ataatcaaga
    49261 aaatggggaa agttggaact tagaaaaaca tgagcattgg gtaaatccgg atgtgttctt
    49321 tccggagcaa aaaagccatt tccattatat tggctcattg acaactccgc ctaccagcgg
    49381 gccaatccaa tggtttgtaa tggatcatgt aggaaaactg aaccaagagt ttcttctccc
    49441 cttcgatggt cagtatgctc gaccgaacaa ccgaccaatc cagcccttga atggaagaga
    49501 aatttattat ttcgaggagt ttgagcaatg aatattcagc agatgaaata cgtggtcgct
    49561 gtagcaaaca atggtagttt cagagaagcg gcaaagaaaa tgtttgtctc ccagccaagt
    49621 ctttcagctg gtatcaaaga attagaaacc gagttaggga tcacgctgtt tactcgaacg
    49681 aatcgagggg catatttaac agaagaaggg caagacttct taaatcgtgc cgagaaaata
    49741 ttggtccagc ttgatacatt agaaactcac tatctaacga gtgaaaagag agacaatttt
    49801 tcgatcgctg cccagcatta tgatttctta ggtcctttga ccgcacagct actcgaggaa
    49861 ttcaaagacg agatcaaaca atttcggatc atggagacga caacagcgag agtgatcgaa
    49921 gaagtcaaag agcagcacag tgagatcggc attatttata tgaatgagca taatcaagct
    49981 ggtatcagaa gatatttaca acaaggagag ctaagtggcc gcagcattgg aaaattcaaa
    50041 acgcatattt ttttaaggca aggacatcca ttagctgaac acgcagagat caccaaagaa
    50101 gaattgttat cttatcctca agttcgtttt acacaggatg gaaataattt cccgtatttt
    50161 tatgaagacc ttatcgagat ccctgatcaa gaaacagtga tttatacgag tgatcgaggt
    50221 actttgatga atatcgttct tgaaactgat gcttacgctt caggatctgg tattgtgatt
    50281 ggagggattc gcgagcactt gcggttaatc cctttggcag aaggcgaact aaatgaattt
    50341 tatatcattt attcggcgaa acgtccgctc agtgaaatcg ctcaaagatt tatcaaagag
    50401 cttactcggt tactggacca gcagagctaa gaaaagcaga tgagaacgct gtttattgaa
    50461 caccgttgat caaaaaagag gggttgtgac agaattttgt cacaactcct ctttttgtag
    50521 caaacaattt ataactaatt gctgttgtgg gaaagtacgc aaatatgatt ctagaaacac
    50581 tcattgatta cctgttttgt ttcatagctg taattttttc ttcttctggt gtcacgataa
    50641 tcgtcttttg gttttcataa ataacataac caggcttggc gccatttggt tttcggatat
    50701 gctttacctg tacaagatca accggcactt gggcagagta tcggtatttt gaaaaatagg
    50761 cagctaactc ggcagcttct gtaattgttt catctgaggg cttgtcactt ttaatgatga
    50821 cgtgcgaacc gggtatattt tttgcatgaa gccaatagtc ggttttttta gctgtcttca
    50881 ttgtcagctg gtcattttga agattgtttt taccaacaag aatgagcgtt ccgtcagaag
    50941 aaaagtattg atcaggctga gatggtttct tacgtttttg tttttttaag ttcttctttt
    51001 tcaggtatcc ttctgaagtc aattcttctt taattgcttc gatatccatt gggccggcaa
    51061 tttccagttg agataagaca gattcaagat attggatttc atctttggct tcttggattt
    51121 gttcgccaat cagcttaaca gcgttcttca gcttttggta tcgatggaaa tatttctgtg
    51181 cattttgatt tggtgtcaat gccggatcta gtgctatttt gattggccga tcttcttcat
    51241 aataattagg taaaacaact tcttttgcgc cgcgtggtac ttgtgtcaga aaagtagtaa
    51301 gtagttcgcc atttctacgg taattctcag cgttttcgga ttctttgagt gtttgttcac
    51361 gttttttcaa tttattttta tttcgtttta gttcattttc gatttttcga atcagttctc
    51421 cgccttgttg ttttgcccga tctttctctg ctttttcgtg ataatagcta tctaataatt
    51481 gactgagtgt tggataagct gttacagcag atgcctgttc ggacaatacc tgataagcaa
    51541 tcggtgtgaa aaaatcttta ttttccgttt cgtaaaaagt aggaataggc tgatggctga
    51601 tggctgagaa aaattcgtcc catacaacca tcttttcatt aggacgttcc agtaatcttt
    51661 tggtcagctc ttgagcgata tcgaaaccga ttccctgaaa ctgacgttgg attgcttttg
    51721 gatctagttc agtttgggaa agccgctgaa agattttttc tttctcggag ctaaatgggt
    51781 tcaagacctc ttgttttggc ggagcaacat attctacacc aggaagcaaa gaacgataag
    51841 tgttttgaga gcttccaatg tgtttgatcg catccagtat ttttccagtt tctcgattaa
    51901 ctaagacgat cgtactatga cgtcccatta attcaacgat caatatgata ttttgtagat
    51961 cacccaactc gtttcgttta gcaaagtgga aatggatcac tcgatcattt tcgatttgtt
    52021 cgatgtcttc taaaatagcg ccatccaaat attttcgaag catcatcacg aagttaggcg
    52081 gattatcagg attctgataa tcgatttggg taatctgtac acgagcataa cttgggtgcg
    52141 cagataataa taatcgatgg tttttgccgc gtgaacgaat caccagcacg atttcatttt
    52201 cataaggctg atggattttc gagatccggc cagatagtaa cgtttcacgc aattcgttga
    52261 ccatcgcgtg ggtaaataca ccatcaaagg acatggttca ttcctcattt cttttcataa
    52321 gtatattcat tataacgaaa aaaagaagaa aaaccaattt ggccgaatag taaagcaaaa
    52381 gtctagaaaa atcttggact aattacataa aaaacagtgt ttctatcgtt gaaatccaaa
    52441 tttttaggt
//
LOCUS       DAPBBR010000018        50665 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPBBR010000018 DAPBBR010000000
VERSION     DAPBBR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.018"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..312)
                     /locus_tag="RD488_001059"
     CDS             complement(<1..312)
                     /locus_tag="RD488_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657149.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YE"
     gene            434..1018
                     /locus_tag="RD488_001060"
     CDS             434..1018
                     /locus_tag="RD488_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657150.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            1029..1274
                     /locus_tag="RD488_001061"
     CDS             1029..1274
                     /locus_tag="RD488_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657151.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            1280..2002
                     /locus_tag="RD488_001062"
     CDS             1280..2002
                     /locus_tag="RD488_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657152.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            2133..2876
                     /locus_tag="RD488_001063"
     CDS             2133..2876
                     /locus_tag="RD488_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657153.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            2882..3247
                     /locus_tag="RD488_001064"
     CDS             2882..3247
                     /locus_tag="RD488_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657154.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            3263..3793
                     /locus_tag="RD488_001065"
     CDS             3263..3793
                     /locus_tag="RD488_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657155.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            3955..4185
                     /locus_tag="RD488_001066"
     CDS             3955..4185
                     /locus_tag="RD488_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657156.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVRLPVSELKK"
     gene            complement(4389..4868)
                     /locus_tag="RD488_001067"
     CDS             complement(4389..4868)
                     /locus_tag="RD488_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657157.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            4988..6325
                     /locus_tag="RD488_001068"
     CDS             4988..6325
                     /locus_tag="RD488_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDT7657158.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            6348..6875
                     /locus_tag="RD488_001069"
     CDS             6348..6875
                     /locus_tag="RD488_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657159.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            6862..7425
                     /locus_tag="RD488_001070"
     CDS             6862..7425
                     /locus_tag="RD488_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657160.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            7848..8585
                     /locus_tag="RD488_001071"
     CDS             7848..8585
                     /locus_tag="RD488_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657161.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANHQD
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(8602..9018)
                     /locus_tag="RD488_001072"
     CDS             complement(8602..9018)
                     /locus_tag="RD488_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657162.1"
                     /translation="MNKKRKLSVLITLVSILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETVTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            9410..10657
                     /locus_tag="RD488_001073"
     CDS             9410..10657
                     /locus_tag="RD488_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7657163.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETAKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTETDTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            10927..13317
                     /locus_tag="RD488_001074"
     CDS             10927..13317
                     /locus_tag="RD488_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDT7657164.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     KFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            13366..15201
                     /locus_tag="RD488_001075"
     CDS             13366..15201
                     /locus_tag="RD488_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7657165.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            15270..16133
                     /locus_tag="RD488_001076"
     CDS             15270..16133
                     /locus_tag="RD488_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7657166.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            16123..17232
                     /locus_tag="RD488_001077"
     CDS             16123..17232
                     /locus_tag="RD488_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7657167.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            17571..18371
                     /locus_tag="RD488_001078"
     CDS             17571..18371
                     /locus_tag="RD488_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657168.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            18459..19265
                     /locus_tag="RD488_001079"
     CDS             18459..19265
                     /locus_tag="RD488_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657169.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            19497..20366
                     /locus_tag="RD488_001080"
     CDS             19497..20366
                     /locus_tag="RD488_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDT7657170.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            20386..20733
                     /locus_tag="RD488_001081"
     CDS             20386..20733
                     /locus_tag="RD488_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657171.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            20746..22008
                     /locus_tag="RD488_001082"
     CDS             20746..22008
                     /locus_tag="RD488_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657172.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            22088..23464
                     /locus_tag="RD488_001083"
     CDS             22088..23464
                     /locus_tag="RD488_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HDT7657173.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            23461..24090
                     /locus_tag="RD488_001084"
     CDS             23461..24090
                     /locus_tag="RD488_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657174.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            24109..24588
                     /locus_tag="RD488_001085"
     CDS             24109..24588
                     /locus_tag="RD488_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657175.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            25090..25143
                     /locus_tag="RD488_001086"
                     /pseudo
     CDS             25090..25143
                     /locus_tag="RD488_001086"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25147..25746
                     /locus_tag="RD488_001087"
     CDS             25147..25746
                     /locus_tag="RD488_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDT7657176.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            25762..26238
                     /locus_tag="RD488_001088"
     CDS             25762..26238
                     /locus_tag="RD488_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657177.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            26255..27157
                     /locus_tag="RD488_001089"
     CDS             26255..27157
                     /locus_tag="RD488_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657178.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQENNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            27230..27424
                     /locus_tag="RD488_001090"
     CDS             27230..27424
                     /locus_tag="RD488_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657179.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKKRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            27529..27957
                     /locus_tag="RD488_001091"
     CDS             27529..27957
                     /locus_tag="RD488_001091"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657180.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNEETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            28192..28779
                     /locus_tag="RD488_001092"
     CDS             28192..28779
                     /locus_tag="RD488_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657181.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            28779..29678
                     /locus_tag="RD488_001093"
     CDS             28779..29678
                     /locus_tag="RD488_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDT7657182.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            29678..30592
                     /locus_tag="RD488_001094"
     CDS             29678..30592
                     /locus_tag="RD488_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657183.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEDFIPAEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCEGYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     DARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNASNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKEAE"
     gene            30644..30859
                     /locus_tag="RD488_001095"
     CDS             30644..30859
                     /locus_tag="RD488_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657184.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLQQFWLNNFSYKDFIKEKANRLY"
     gene            31049..31303
                     /locus_tag="RD488_001096"
     CDS             31049..31303
                     /locus_tag="RD488_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657185.1"
                     /translation="MKKEELIDMFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLISDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            31482..32531
                     /locus_tag="RD488_001097"
     CDS             31482..32531
                     /locus_tag="RD488_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7657186.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGSPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     APNPTPAPAPSNEKVLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPR
                     ANDNNPYHGYSGEWRYNVNGTYQGMMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRN
                     GNPVVTWITYNYASPQFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINAST
                     YERAFNVTGMAVAVR"
     gene            32708..32938
                     /locus_tag="RD488_001098"
     CDS             32708..32938
                     /locus_tag="RD488_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657187.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            32941..33198
                     /locus_tag="RD488_001099"
     CDS             32941..33198
                     /locus_tag="RD488_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657188.1"
                     /translation="MINEDFRSEQKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            33415..34290
                     /locus_tag="RD488_001100"
     CDS             33415..34290
                     /locus_tag="RD488_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657189.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            34300..35094
                     /locus_tag="RD488_001101"
     CDS             34300..35094
                     /locus_tag="RD488_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657190.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            35123..36241
                     /locus_tag="RD488_001102"
     CDS             35123..36241
                     /locus_tag="RD488_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657191.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            36274..36594
                     /locus_tag="RD488_001103"
     CDS             36274..36594
                     /locus_tag="RD488_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657192.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            36849..37538
                     /locus_tag="RD488_001104"
     CDS             36849..37538
                     /locus_tag="RD488_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HDT7657193.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            37575..37742
                     /locus_tag="RD488_001105"
     CDS             37575..37742
                     /locus_tag="RD488_001105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657194.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            37762..39390
                     /locus_tag="RD488_001106"
     CDS             37762..39390
                     /locus_tag="RD488_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657195.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            39441..39812
                     /locus_tag="RD488_001107"
     CDS             39441..39812
                     /locus_tag="RD488_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657196.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            39897..40097
                     /locus_tag="RD488_001108"
     CDS             39897..40097
                     /locus_tag="RD488_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657197.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            40231..41457
                     /locus_tag="RD488_001109"
     CDS             40231..41457
                     /locus_tag="RD488_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657198.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            42307..43632
                     /locus_tag="RD488_001110"
     CDS             42307..43632
                     /locus_tag="RD488_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7657199.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            43625..43972
                     /locus_tag="RD488_001111"
     CDS             43625..43972
                     /locus_tag="RD488_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657200.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            44287..45144
                     /locus_tag="RD488_001112"
     CDS             44287..45144
                     /locus_tag="RD488_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDT7657201.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            45164..45724
                     /locus_tag="RD488_001113"
     CDS             45164..45724
                     /locus_tag="RD488_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HDT7657202.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            46767..47534
                     /locus_tag="RD488_001114"
     CDS             46767..47534
                     /locus_tag="RD488_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HDT7657203.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            47560..48105
                     /locus_tag="RD488_001115"
     CDS             47560..48105
                     /locus_tag="RD488_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657204.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            48106..48672
                     /locus_tag="RD488_001116"
     CDS             48106..48672
                     /locus_tag="RD488_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657205.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            48687..48935
                     /locus_tag="RD488_001117"
     CDS             48687..48935
                     /locus_tag="RD488_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657206.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            48955..49194
                     /locus_tag="RD488_001118"
     CDS             48955..49194
                     /locus_tag="RD488_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657207.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            49565..49846
                     /locus_tag="RD488_001119"
     CDS             49565..49846
                     /locus_tag="RD488_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDT7657208.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            49836..50177
                     /locus_tag="RD488_001120"
     CDS             49836..50177
                     /locus_tag="RD488_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7657209.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
BASE COUNT        19207 a         6821 c        10102 g        14535 t
ORIGIN      
        1 ctcatattca tagctatcaa ttagctcagt tgaactataa gctttttcta gtagttccat
       61 ttcccatttt ggagagtttg gatcactttt tcttagtcta gctatatctt ctaaaatttt
      121 cttagaagta ttatcctcgt aaatatttgc taaatcagat aatttatcaa ttaaatctaa
      181 aataagcgca ctgtaattga cagctattgc agaacgataa tttccctgat aaaaactact
      241 tctaacttct tctaataatg gaataattct aggattttta acttttttta tttcatcatc
      301 taatataaac atataaatct ccttttttta tttgtatgac aagtttacca taaaaaaaaa
      361 ttaaaaagcg agacatattt atgttgttgt gttatcataa taacataaat atgtagagtg
      421 agatgatgaa aaaatggatt tgaaacaatc gttttacatc tggttatatc ctgataatcc
      481 tatgtcaata atggctgata tttttgtagt tagcatctta ttgtatttat tttatctaat
      541 tttctttcac aatttaatcg ggtacatgat tcttgattgg aaaggaatgt tcgatataga
      601 aagaaaacca tttgctaaca atcaaaccta taccgtcttc gaaagtggag attgggaaga
      661 aaatgaagtt gatgtgatcc atgaaattgg attagcttta tcaggaatac aagatgctga
      721 tgttttggta tcaatgacaa cggatactgg atacaacgct tatgaggtat tttatcttat
      781 gtattttata tggcgtgatg gtcaagaaat tatcaatggt cgtgctgaaa aaacaatcaa
      841 ttctaatact gaaatttctt tttgtatggg tgaaggggaa atgattgtat ataaagatgg
      901 gtcagcaaac attaaaacag cctttggtga tattgaaaca agtattaagg aacttaggga
      961 atatgtgcag aacccatata attttcaata tttagcagga agaataaatt tagtttagga
     1021 gtaaaaatat gaaaaaaatt ataaatcaac caacaaatca cttgataatt gaaggtgtta
     1081 ttttcgtaac aatgtatttt actgtaggaa atggcatctc aaatacaatc attcaaaaaa
     1141 atccacaata cctattattt agtctttatg cttggattgt acaaatggtt tgggtttcca
     1201 tattgatgct gttgttttat tggatagtac gggttattct tttattgtta aacaaaagaa
     1261 aaaaggatag gtgaataaaa tgaaatcaac taaattgaag gttgtattgt tatcgacagc
     1321 agcattaata acccttacag catgtggtac aactaatagt gctaataata acaaagacac
     1381 aaagtctagt agtacgatgg ttactaaaaa cagcactaca tcggcatcaa caacaatgtc
     1441 ttcaatgact gaaaataatg ctgaaaagta tcaaaaatac gaagacatta ataaaggtca
     1501 aaagccggat gaagtttata acaactttat taatacagta aaaaatgatg aaaattatgg
     1561 gaatgatcca ttgcaaaata aaaatctgac tatcgttctt tacaaacctg attgtccaga
     1621 ttgtcaaaaa gcagaatcaa aaatcatgca agaaataaaa gaaggattta gttatgctcc
     1681 aacattaatg catgatatta ccataaataa accagcttac gagtattacg cagttgctgt
     1741 agatattact gatggtgtac ctgagtgggt acaaaacatt cctggtctgg ctgatgagaa
     1801 caatcaatat catacgccaa cagttgcagt agtaacacca aagaaagtta acggcacact
     1861 atactgggat gtaatgggaa tgacaacaaa tacaactgat gaaatgattg aaagtacaac
     1921 taaatattat atggatttgg gagcatataa attatatcaa caatcagagc ctgttatgga
     1981 cgatcaatcc aaagttaaat agatctttag ggcgtaagcc ctattttttt aaaattaagt
     2041 gataacaaat aaatgatttc tgaaacaaac gttcttactc aactactcga aacacacaag
     2101 ctaattaact agattataaa ggagaatgcg taatgaaaga aatcagtgca aatgaagctc
     2161 atattccgca aaagaatcag gttggtatat ataaggtgct tcatggtgaa ggaatttata
     2221 aaatacagtt acttaccggt tacaataatg gtgcaaatgg gaagtggtta aaggcaacaa
     2281 gtattcgtga acttagaagt gaagtagaaa aaattaggct tggtctcaca agtgaagaaa
     2341 tagctaaact gaagggaaat aattcttttg taattgaaaa agaaaaggaa aaacatctac
     2401 tttatcgtga gctgaaaatt gaagaatact atgaaattga tttacctgaa aaattaagaa
     2461 ttattgatca acgttcagaa gaaaaatgga aaactgaaat atatccaagc ttaaatgact
     2521 acaagacatc aggaaagccc atgtataact acacaggctt tttaacctac acacaataca
     2581 aatatgcctt tcgcaaatta aaaggcatta aacaagctga aattgctctg tatgagatga
     2641 aaaaagtgga tagattgaaa ttgattcaag atttagtgca aaatacatgg aatcaagcga
     2701 ttgtcgagct agaaaaagaa aatgggaaaa ttttaactaa taaatatctg atcgtaaatg
     2761 aaattgaaga attaattggt ttattttcat gtgaaaaagg tgaagtcttc ttgaagtcat
     2821 caccaaccta ttcaattttg gacagtccgt atcagtttat acaggcaagg agatgagtta
     2881 gatgtctagc ttgaaagatg actatatcca agcaaaacaa gagtatgaaa aaatacagat
     2941 gttgaaatct gagaaagtcg aattattttt aacacaaaaa ttagcagagg atcatattgc
     3001 taacttagat gctaaaactt tagaggaata tgatcggcag tttaatcaga tacatcacaa
     3061 tatcattttg cttgttgagc aggcaaagcg aaggtttgaa aaagcggaat atgatctatt
     3121 agatcaagga attgtatgct tggataaggg attgcgaaga tattatggtg cagagttaaa
     3181 aaagcaaaat gtagatagaa atgcactaaa acatgaaatc ttagaattga taatgcaacg
     3241 aatttgaagg gatagaaagc aaatgtcaca aaacattagt gctgtaaaac aattaataga
     3301 agaagattta gagaccacag ttcagagatt agcggaacga atccattttg caaattatca
     3361 aaccatctct aactggtcaa gcaggaacag aaatccggaa gaaattccaa tgaaattttt
     3421 ttatcgaatc ggaaaagaat atggtgttga tccgataaaa attttcgaga agaccatgat
     3481 ttattactat catggaacac ctaacgaagt gttagaacat cttttggaag aggcaaaaga
     3541 aaaatcatca atattagagc tatcgcaaaa tgacaaagtt attcaagtga aatgcgttga
     3601 tccaacagga aagattattg tcggttttga tattgaaaga aaatccaaaa tagattttat
     3661 tacacaatta aaaaagataa ataatttaga tattctaacg cttagaccag atcatgaaca
     3721 gttgtttatg agttttaaaa aacaattgaa agaaatacaa aaaagatata acaaggtgtt
     3781 tcctaatgcg tgaaaagctc aaagaaatca gagttttttg gataattaac aaagaatgta
     3841 tcatcttata tactcttgga tttcttagca tgatcttgtt ttggtggtta tatttaaaac
     3901 agtaattgga gagggtcaag aggattttta tcaagataag gatgtggaaa ctgcatgtgg
     3961 aataatagat taaaaacagg attgttatta atagttattt cctgcgctat gatgattggt
     4021 atgaggatac aaagggaaca atcctatttt gaagtttctg ctaacaacgt aatagaaaaa
     4081 tgctattacg gtcaacatta ttggagtgag gaagtcagag aaaatataga tcgtgaatat
     4141 gttcaaagaa ttgttagatt accagtaagt gaactaaaaa aatgatgaga ttatcagcat
     4201 atcttttaat gtttttgaat gtggtcacgt taatctttgt agtaatcggt gtgactttcg
     4261 atttaatgga atagtgggaa atctataatg gaaaaaagag acacgaatga acatattttt
     4321 tgaatcaata ttgttgatgg tttttgcgat cagcgcttac cagaaatcta aaaaagagta
     4381 atgattgttt aatcatcact ctttttttgt agggaaattg aaatatgtgg agcttgtatt
     4441 ggtttagtta ggattgcttg gctataagga gctagttctt tatcaaaacc atcaaagtag
     4501 gttttcagta gcgatttaac tgatcgctca tcttgtttga tttggataat ttcagcatcc
     4561 aaatcggttg tgagatcagg agcttttgat gcgattacct gatttttttt atcttccaac
     4621 tctcttaggc tgtttaacaa gttgtaaaaa gaatcatttt gattgttcat tccaacgtga
     4681 gttgcaattt taacagaagt ttcgtccgta ttgtcatcaa aagaactcat tggaatatca
     4741 agtagtaacg aggatgtttc ttttactgac tttttcttta cagcattttt tgtttttcca
     4801 tcttttttgc tctttactcg agatgttttt ggagctagtt taggtaaatc acttgtttta
     4861 tcagtcattt attagctttt cctttctatt aatttatgtt attatattat cataataaca
     4921 taaaaaagta cactttttgg gggcgtagtt attgaaaaaa tctaagagaa agattgccac
     4981 attgcttatg ttaatggtgc aatttacagg gattgcaatg agtgtaatca caataaatcc
     5041 gcaagtgata catgctgatg ggatagctac ttatgatgca caatttaact gtactactga
     5101 aggtagtggg tcaggaacag atagcgatgg aaacgatact ggaagtggcg ctgtaacagg
     5161 tgatgtagcc aaaaatattg aagatattta caaatacatg aatggagaat atggcttatc
     5221 aggtgctagt attgcaggta ttttaggtaa ctggaaacaa gaatcaggta ttgatcctcg
     5281 agcagtagaa gggtattacg gagatggaca gagagaagtt gacttcatca aacaatttac
     5341 tgatggtctg atgggtattg gctatggtca atggacagct gggcgacata cagcattagt
     5401 tgattggtct aagaaaaata atggcggttc ttggtggact acagaagccc aattggactt
     5461 tatgttcaaa ggtgatgggg gattcgtagg aatattaaaa gattatgctt taaatgcttc
     5521 tgatgatgtc gtagaaaatg cagtaacttt tcataaaaac tgggaaattt cagctgattc
     5581 cgaatcagct gtaatagctg tacgtggtga aaatgcaaaa gaaatctgga agtacatgaa
     5641 aagcaagggt atggacggtg caaaagatga aagtaagatc aataaaatat ccggaggttc
     5701 aagtaccgga gatggatcga ataattcatc aagttcagca tcaggaacag tagaagatgc
     5761 ctgtgcaact acggatgacg ctaattctgg ttctggatca attgggaaag aaggaaaaat
     5821 taacggtaaa aaaggtcaag taatagcgaa tatgacttat gaagaagctt tgaaaaaata
     5881 tgggaaagcg atcacgctac caaaattcaa agaaccagat tggtcaactt caccttttaa
     5941 cggaatatat caaggtcagt gtacagagtt gacgtgggct tatatgagcc aattatacga
     6001 tgggaatcaa ccgactactg gaaatggtgg ttatgtatgg gaaagctaca aatcggcagg
     6061 agcaaaaata acgaacaaac caatcgtagg ttatgggttt agtgcttcag atggatggtt
     6121 atgggctgtt ggcgatgcag ggcatactgg tgtagttata gcggtgtttg aagatgggtc
     6181 atttctatgt gctaacttta atgttccacc aacccaagct ccaacaaggg gagtttcggt
     6241 aactttgatt gatggagtgg acggatcaga taatgtgcat ttctttagcg gtgtaggaaa
     6301 agctaaattt gaaatcgaaa aataaattgg aatgaaggac gatatagatg aatagtaaag
     6361 tgaaagatac aattatcatt tctttgcttt ctggtatgtt attagcactg cttgttggaa
     6421 tcctattctt caataagcag aatcaggaca tagaagctga aaaacacagt gtgcatattg
     6481 aagataagct gacattcttt aaagaggtta aaccaaatga ggtggatgga ttacggaaag
     6541 atttagaaaa tgatattcaa gaaatgttga atggatcagt tcaaaataag tttgcagatc
     6601 aatcaggtga agaatttttg agaaaactat ttattgtaac aggtaaacca ccaattactg
     6661 ataagagtag tgagaaagaa aaaatcgagt actataagcc ttttactttt aagctaacaa
     6721 actttggaat taagacatct agtagtgggt tgtatgaagc attgaccgat tttgaagttc
     6781 aatacaatgg aaaaaaagtg tatgatacca cattaaccat cacactaaat aatgataaga
     6841 aagtgactgg gggtgctttt tatgcaaaat catgaaatca ctactgctaa aaaggcgatc
     6901 ggaatacttt ccataattgt gatcctttgt tgtgtggtac tatttcaaaa gaaaaatgct
     6961 tatgataata atgtcaaaga attggaagac cttaaaagta aacaaatcga agtagtcaag
     7021 aataaccaga aagtgaaagc tatgcaggaa gctcaataca aagaattggg gaatgctgaa
     7081 atcaaggaac aaagtaggaa attctttaat ttattttaca actggaattc atgggaaaaa
     7141 tatacgaaga atatgaagga aatacaaaaa gaatttcctc agatagtaaa gtctagtcct
     7201 gttgatattt ctggcacgat ggtaggcact ggtaatagtc caatatctag ctatactgct
     7261 gattactata caacaaatca aaaaggtaaa atggttgaat tgattacaca gacaagaaat
     7321 actccaacaa cagcaacaac aacaatttgg cgtggagtaa caagcatagg agaaaatcaa
     7381 ttgttttact tggaggattt agatagctat gtaagagcgg agtaaaataa aaaaagagct
     7441 aacggtacca acgttagctc tttgtgctga cgatgataac aaaacctacc gaaaaaggat
     7501 tgtttcatca caaacacaaa cagaaaagaa ttgataaaaa acccgaacct cagaattttt
     7561 attaatcaat tcatttagat tataataaat tgagctgaac attacaatac gtatatgttg
     7621 taaaacgtaa aaaaagtcaa aagtaaatac tttcttaaaa agtcaaataa aactattaaa
     7681 gacaatatat atggtttatt tgacataaga aaatggtcta gatgataatt gtaatataga
     7741 attgtaggct taaataaagc ataaaatacc ttttatgata aggtatagct cttaatttta
     7801 agcagttttt agatataaga gtgaaagtaa agtgggggag aataataatg gcagatcgta
     7861 aattagaaaa gttattagaa gaaacgtgga atccaaaaga atttagtgaa ttttttatgg
     7921 agaattttga aactgactta gcagtgattg ttaaagatgc tcttagagag caagggtatc
     7981 ctgaaactgc aaactatata aacattaatt ttactttgta tactgaaaat aaaggaactt
     8041 gggatttttg ggctacttta gcaaataagg agttaagtga taaatcagac acaggaattc
     8101 gtaacttttt tgaatcaaac agagatgatt atatgtatgc taaccatcaa gataaattga
     8161 actttagagt agagtttgat gaaacacctg aagaatttat agaaagacaa ccgcctaaag
     8221 aaaatgtagc aaaggtattg gaagatcgtt ggaattcaga tgaaatagtt tcaacaatta
     8281 gcgaactagg cggacaatat gaaccgctag tagaagcggt tagagaagag ctaagactga
     8341 ataagtttcc tgatgttcaa aatattgatg tttctcaaat tgaaataaac gtcaagatca
     8401 cgaataaact tgattatggt agttgggcag atatagcatt agaaaaatac atctactcaa
     8461 cgttaaaaga gtttatcgaa aatagaatgg atatcatgta tctacagcat ccacagtatt
     8521 taaactttgg tgttgaaata gctacacctc ttgaagaatg gaaaatggag caagggcttg
     8581 actagccttt gctccatttt tttattttac aaatgaatac agttcgtcgt ttttaccaag
     8641 aatgattgtt tgcccaactt tgagattgtc aggtgatcct tcagcggttt gtaaggagaa
     8701 cgttccgttg aacttatcgg ataccgttat aggtagcttt aattctgatc cttcctcatc
     8761 tttgagaatt gctgtttttc gttcatcaaa ataaacagtc tttattaaat aatttttcgt
     8821 agtgatctca gcagatttgt ctttttttgt agtagtaaca gtttctttag aattagaggt
     8881 attttctacg actattccat ctttggcatt tgagcttgtg tttatttgat tgaatatttt
     8941 cagcgacaag ataccgctaa gaatagtcaa tatagaaaca agtgtaatta atactgataa
     9001 tttccttttt ttgttcattt tttcttaact tcctttttgt tttgattagt tagatattcc
     9061 ttatctaaca agccttttta ggctattaaa tgaagataaa ccccaaaaaa atattgcaat
     9121 tatgacagtg caatggtact attattatac aataaatttt gcgaaagggg taggtctaaa
     9181 tcgcaaacaa aaagaaattg aacctagaca aatacaactt gtacaccgca agggaagcaa
     9241 gtttgatttt gggtaaaggt agaaattatg ttacaaacat aatcaactat tatccaaatc
     9301 gtttgcctaa aggttcgttc aagaaagtgg gtgacaaaac ctatattata acggaagaag
     9361 gaatagaagc attgcgatca caaacagaaa ataaaaacaa aaagaaggaa tgaatatgaa
     9421 gaaaaattcg cttggtatgg ttttatttgc atcagctgta cttgcggggt tatcagtacc
     9481 agtaacctca catgctgatg aatggactgc aaacacaccg gatcaaatcc aaattacaac
     9541 aggacaatca agttatgcgt tcaaaaaagg agatactatt tggtcaactg tagagaagct
     9601 taaaagctta ggttacaaga ctactgttgc tgagtttgcc gaattgaaca atgttgattt
     9661 ggcaaaagga gaacaacgga ctatcccaat tggacgaact ttcaacatca gtaaagatac
     9721 attaacagtt aaggaagcag atggcgaagt agttagtcaa actgttcaaa aagataaacc
     9781 tgatcctgtt gaaaatacgg agcaagagaa caaaaaatcc gagactgcaa aagaatcgga
     9841 accaacagca aacacttctg ataagacaga aacaagtgct tcaagtgttg atggagcaag
     9901 ttcatctaat acaaataatt ctacaagtga gaaagaagca tcacagggaa caagtgaaag
     9961 tagcactacg gaaactgata ctggaacatc aacaaataac tcacaatcaa catcaaatga
    10021 tgcaaatgaa tcaaccagta catcttctag tgatcaatca caaacaggtt cgagtgatga
    10081 aactgacagt tctacttcac caagtaaacc cgaacaacca actaatgttg tgctaggcgt
    10141 tccatttatt agtcaaggta acacaatgct ttgcgaagga acatctttgc tagaagcgtt
    10201 acattataaa ggtgttgcaa caaatcaaga tttaatgact tttgttaaat caatgccact
    10261 atctcctgat aataatccaa ataatggttt ttctggtgaa tggagacaca atgtggatgg
    10321 aacttatcaa ggtatgaatc cggctcctgt agtttcatgg ggtgttgcta atggcggaaa
    10381 tgttgtagat atttctggtt catcggtaca aggattaaaa gatgagattg taaatggaaa
    10441 tcctgtagta gcgtgggtaa cttatgcctt tgaacctgct caacataaat caatgttttg
    10501 gggcgatgct atttggaatc gacatgtagt agccgttgat ggatttaaag acggttttta
    10561 ccatgttgtc gatcctgtgt ttggggcaag ttggattaat gcaggatcat ttgaaacagc
    10621 atataacgta tctcaattag cggtttcggt acgttaataa aagagattgt ttatatacta
    10681 agtagttaag tatagtcttt atttgtcctt gcttaactac ttagaaaact tgttgctcat
    10741 ggtgggtaga actaaaaggg gtgatgctat gaatactaga gcgttgaaac agcttgcttt
    10801 caacgaaaaa agtgattaat aggtgtggtg attttaactt aggaatgggc gcgaaggtca
    10861 ttaccacacc gacatatcgt ggctcatttt cttcgcctaa ctggtataaa gaaggagtaa
    10921 cgagagatga agcatgaaaa aacgataatt ttaaaatcaa aaataattta ttgttttgcg
    10981 actttagtaa tggtgttatc tacgcttata atgccttttt cagcaataag agctgaagca
    11041 gatgtcacaa aaccgacaag tgcaaaattt acagaaactg gcgtaaaaac agacggttat
    11101 attagggtta atatgccgaa tcatccaaat gaatggatga tttcaagtca atttaaagat
    11161 tctcatggaa atattggata ttgtatggat tcagaattgc catccccaac aggaagtgga
    11221 gccggaagct tgaagtacaa gggagctggc agtgatgagt tctatcgtat gtttaaaggt
    11281 ggttttccat caaaaacagc aaaggaactg ggtgcaggaa atgatacaga agcatggtat
    11341 gcaacacaat tagtttcatg ggttttagcc ggaaacttta aagtttcaca gattgtatgg
    11401 tcacatccaa accataccgc cgcagaaaca gctcgtgtaa aaaaagcatt tgaaaaaatt
    11461 tatgactatg ctaagaatgg aaaagatacg cccaacactg agttttctat cacagcttct
    11521 aagacagctg acgaaggaaa atatcacact ttcacatata aaacagcatc aaataagact
    11581 ggtaatgcga agctcacttt tacatcagca aaaccagctg gtatgaagat ttatgatgca
    11641 gatggtaaag aaattactaa caacactgtg aaattaaatt caagttttac tattaaagta
    11701 cctgtgacta caccaagtgg tactttgtca tttaaaggta ctgctaatgt tagcacaacc
    11761 aatcctttta cttttgatgg acgaggcgtg tatcaagatg ccgtagttat gatcactact
    11821 tcagaaacaa aggactctaa atctttgagt gctaaatgga caagagctgt tggtcaggta
    11881 acagttaaga aagttgatca agatggaaat gctttaaaag gagcggagtt cactctaact
    11941 gacaataaca atgctaaatc tgttaagaca accggagatg atgggttagc tacgtttgat
    12001 ttgcaacaag gcttaacata cagcttagaa gaaacaaaag ttcctgaagg ttatcaaggt
    12061 tcatttaaaa aggatggtat tactgttaat accgatggac aaaaatttag ttacactgct
    12121 acgaacacaa ttaaaaaagg taaagtaaaa gttaaaaagg ttgaccaaga tggaaaacca
    12181 ttagctaatg ctgaatttac cttgacggat gattcatccc aaacacaagc agaaaaaaca
    12241 gatgaaaacg gacttgcaag cttcgatatt gtagcaaaca agacctacag ccttgaagag
    12301 accggagtac caactggtta tacaggcgca ttcaagcaag aaggaattac cgttaaagat
    12361 gatggacaaa cttttgaata tacagctaca aacactttga aaaaaggtgt agtaaaagtt
    12421 cataaagtcg atcaagatgg aaaacctttg gcaaatgcag agttcacttt aaccgatgaa
    12481 aaaggtgcaa cacaagtaga aaaaacagat gaaaatggac ttgcaagctt caatattgta
    12541 gcaaacaaga cgtatagtct agaagaaacc ggagtaccag taggttacac aggtgcattt
    12601 aagcaagagg gtatcagtgt taaagacgat gggcaaactt ttgaatatac agctacaaat
    12661 aatttgaaaa aaggtgtagt aaaagttcat aaagtcgatc aagatggaaa acctttagca
    12721 gatgcagaat tcaccttaac ggatgaaaaa ggtgtaaaag aagttaaaaa gacggatgca
    12781 actggtctgg ctacgttcaa cattattgcg aacaaaactt acaacttaga agaaacaaaa
    12841 gtaccaacag gttacacagg cgcattcaaa caagaaggaa ttaccgtcaa agatgatgga
    12901 caagtctttg aatatacagc taaaaacact ttgaaaaaag gtgtgatcaa agttcataaa
    12961 gtcgatgatc aagggaaagc attagcaaac gcagaattca ctttgacgga cgacaaaggt
    13021 gtaaaagttg tacaaaaaac ggacagaaat ggcttggcaa catttaatat tgttgccaac
    13081 aaaacgtaca aaatcgaaga aacacaaaac cctaatggtt atacagggaa atggtctaaa
    13141 gaaggcatca ccgttgctga cgatggacaa acctttgaat atacagtaat taatcacctt
    13201 gtacctgaaa cagtaagaac aggcggaatc ggtacatcag ccttccttct tgtatttcta
    13261 attgcaggat tgagtatggt gctactgtat tatcgagaac agcacaaagc aaaataaaaa
    13321 agtgttaatg gaaaagaagt aaatatgaaa aaagaaggct gacgtatgaa atcaaaaaaa
    13381 attttttcaa atttaatgct atttggtact ttgctaggag tgggattggg cgcaagctca
    13441 atctcttcta gccttggact aggggggcaa gtagcatatg cacaacaaaa ctataattat
    13501 caaggaactg gaacgattca tatccataaa gtaacaaata ctaatgggga tgggaaccct
    13561 gtctcagata ttgataacaa agggaaagaa atagctttac caaatggtgt aaaacctctt
    13621 gaaggcgttg agttctctta tgtgaaactt actaaagatg aagctaaatc cttgggatgg
    13681 acggatagtg atactacaaa aggtcaacat attgatgatg ctaaagcacg attattacta
    13741 aacaaaaaat acagtgaagt aagtagaatg aagactgatt cacaagggaa tatagacata
    13801 cctatacaag taaatacaga cgatttaaca gataacttgt atttgattgt tgaaacagga
    13861 acagtcaaag gtgtagttga agaagcgtat cctatgattg ttaacgtacc tgaactaaac
    13921 ggatcagatg atcaatactt taattatgat gtacatgtct atcctaaaaa ctatttccaa
    13981 ttaaactcag cagagcttga taaaaaagac gaagatggaa aggctcttgc cggaactgtt
    14041 tttgaattgc gaaaagatga tggatctgat caggttgttg gaacttataa aacagacagc
    14101 acaggtaaat taactgtgga tggtttggaa ttaggtgact attatttcct agaaaccgat
    14161 ttgggaacag atgctaatag aacaacctat ttactagatg gtaaaaaatt caaatttagc
    14221 gttaaacgtg gggagactgc taaagtagtt cttgatgtta ccaactacaa acgacctgta
    14281 attactaagg taattgataa agaaaccgtt gatactggcg aagatgttca atatacattg
    14341 aaaccatcaa ttcctggtaa tattggtaat tacgaaaaat atgttgtcaa agatgttcta
    14401 ggtgcagagt taacttatga ttcatcagaa gtgatcgaag gaatgacttt agatactgat
    14461 tacagtatcg aacgtgacgg acaaacgaca aactatgtct ttactgaatc aggtatggat
    14521 aagcttcaga aacaatttga tgcaggggat cgcttcttta caattttgat gaacgctcat
    14581 actaatagta aagctaaaat ggatacacca cttaagaatg atgtttcaac gatctacaac
    14641 aatggatatg aacccgaaga cgaaacacca gttgatcacg cttatacaat cattggtgat
    14701 caccaattca ttaaaacaga cggagataca agcaaagcat tgagtggagc aaaatttgta
    14761 gtgaagaaca aaattgatcc gaataaagtt acttacctaa aacaagatcc aacaacgaaa
    14821 gctgttactt ggattgcaga taaatctaaa gctactgaat tcgtttccgg atcagacggt
    14881 aagttccaaa ttgaaggttt gcaatatacc tatgatgtag attttgataa acaaggtaat
    14941 ccaacaatca cagataaaaa aatcaatgat tatgctcttg aagaagttgt tgctccttca
    15001 ggatatacac caactagaaa cgatgttcca tttgtggtat cgaatgatga tgcttctagc
    15061 gaagtaacag acatcaagaa ccttaaaaca cctgaaacag ttcgtacagg tggaattgga
    15121 acagtagtat ttctagtggt tgcaggtgtg gcaggaacag ggctatatgt tgtctacaaa
    15181 cgagaacaac acaaagctta atgaaataaa attccctaga gtgtttttgg ctctagggtt
    15241 tctttttaaa aagtgtgtga aaagtaggta tgagcatgaa aaagaagaat atcaagttga
    15301 tcatcttaaa aattgggatg ttgctatgtt taggagtagg tctatatcct gtaattactc
    15361 aggcttatac ctactaccaa actcaacaaa cactaaactc ctataaggaa aaatatgatg
    15421 aagcttctga aaaggagaat gaagaagtct tcaagagata ttcagaagtt aataggaaac
    15481 gaaaagacac agaacaaacc tcagtcacga ttcctgaaga taataacaat attccgtcaa
    15541 atggaaatct tcagaaggat aaattaggtg aattagtggg tgaaattctt ataccaaaga
    15601 ttaatgtgga tttgccaatt tatgatggtg taaacgattt ccaactatca gcaggagcag
    15661 gaatattaac cggaactgat tatccaactg gtgggattgg aaaccattct gttatatcag
    15721 ctcattcagg cattcctaat aaaaaatatt ttacagattt agagttgctc aaacttggtg
    15781 ataaattttt tattgatatt tcagggaaaa aacttgctta tcaagtagat cggataaaaa
    15841 caattctacc aaccgaattt gaggatttgc ttcctgtggc aggaaaagat tatgtaacac
    15901 ttatgacatg tacacctgtt ggagataatt ctcataggtt actcgttaga ggggttagca
    15961 taccttacca aaaaagtatt gttgagaaag aaaagaagaa agaagattta aaggtaaagg
    16021 cgcagatgaa ctggtatcct atcgtagttg taggggtttt attaataata gctgtgatag
    16081 tcattattaa aaaaatagta gcaaagagac gaggaatgaa aaatgaagaa taaaatacta
    16141 ctttttttga ctcttatttg cactttggtt ttaacaattt atcctgcaaa tcagctctat
    16201 catcaattca aaacaaaaga gaatgtggcg gaaatccaag agaaaattga gaaaaaacaa
    16261 actccttcaa aagaggaagt ggcaaaaaaa gtcgaacaaa taaaatcgaa cagcggtaac
    16321 caaggattag acaatactca gaaaacagat aaaggagtag acaatactca ggaaacagac
    16381 ggtggatcat ttgatattcg tgaagctgaa ggaaaggtca atccatacac aggagatgtt
    16441 ttttcaaaaa atcaaacgaa agattttgaa ccatctacct attcaggagc ggttggttat
    16501 gtctatattc caaaaataaa tgtgctagag cttttgtttc taggcgcttc acaggagcat
    16561 ttatatagag gtgtggcaca aatgagtgct actagtctac ctttatcagg taaaggtcat
    16621 caaacagtaa tagcaggtca tcgtggcggt tatacgtcac cacaatttct ttatgttgat
    16681 caattagtag ccggagacca catttatata gattatcttg gtgaaaaagc agtttatacg
    16741 gttttccgaa cagacgttat tagaaattac ggtcagaatt caacactgac tgatattcct
    16801 gatttagata tgttaacact ttatacttgt catccatatc ctcagaacta cgatcgttta
    16861 ttagttagaa gtctaagaga tgaaaaagca aaatacatca cgccacaagt aacagttggc
    16921 aataccgcat acgctgatgc cattgatagt gaatccgttt cagataagcc agaaactgtt
    16981 acatcttcta atgatttatt tgaggatgtt gatcgtgcca acaaggaatt agatggaaat
    17041 aatgatctta atattccgga acaaggtagc gtagagatgc aagacagaac gtttgctgaa
    17101 aaggcaagtt caatatttac aggaattacc aataaacatc agaaaatgct tttagtcatt
    17161 tggactgtat taggagcatt agcaagtcta aaggttctta ttcttttaat caaagagttt
    17221 agaaaagcat aatgaagatt ataaaaattg atagagtaca gtaaaaaggg attgatacta
    17281 ttattgatct cttttttatt ttgaatagag ctagattcac ttttaaataa aataaaaact
    17341 gatcttaatt ccaaagaaaa agtcaagaaa aaaatacaac aaattttttt atcagaatat
    17401 ttatcagaat attattagaa aagataaact caaaagctta atttaatagg gttattggtt
    17461 gtatttagaa ataatgtatg gaaaagctat aaagcaatag ataagatgta gaaaatctta
    17521 tttgtgaatg aaaaacaagt catcgtaaaa tattaatagg aggtgtagta atggtggaaa
    17581 tatcaaaaac agctttagac tcattagcta aactatttag tagcaggttt gatggtgcag
    17641 aatttgttga atatctaagc caaaacgaaa gtggaaaaac tctgatcgaa acactgaaaa
    17701 aagactattt gaatgaaaat gactttccga catggacgaa tattgaagat gctacatggg
    17761 atgtagtgtg tacgatatat tctccttggg taacgattgc tgattttgtt ttagataaaa
    17821 ttggagggga tacataccct gatgccaaat ctcttgctac aagtgacttt aaaacgttct
    17881 atggttatct aatgggtcta ataggcaatg gaatagattt gaaagttacg ccaaaacaaa
    17941 cacctgaaga aattgaaaaa gaaaaaggag aggttcaaat ggcttatgca gatgacagag
    18001 aaaaagtaaa attattggaa ggtaaattat ctgaagaaga acttggaaaa atggtgcaag
    18061 aaatcaatga agacagcaac tattttcctg aattgaaggt atatcaaaac gacgaagatt
    18121 tctttaatga aatgtttagt aatagtccat gggaagcagt gagtaaaaca aatttaggag
    18181 aatggaactt tcaagatgat ctagttgcat ttagcaatga tgggtattta cgatcatatt
    18241 cagaaagtga gtatagagct gaattaaaaa cgtatgaaac ggatattctg atgagctatt
    18301 taaatctatt agagagtggt cagggagagt taagagataa agttgaagaa ctattaaaag
    18361 aagagctata gggattattt caacataaac acaagcagaa aactaccaaa caaaacgtac
    18421 catgcaaaaa gccggttaaa ccggcttttt gctctattat gagaggagat caaaccatga
    18481 gtgcaacaac cgatatggct ttagaagcag taataaaaga taatacagga aatgtcgaaa
    18541 atgtagaaga ctttagcgat attgcaatca atctttcagc atggatttca gctgtaggag
    18601 aagaaaatat cgaatttgag atcaagaata tggatgactt aaaagcaaaa tttcctttta
    18661 tcgcatcgaa actaagtcaa tttgccgagg agaaatcgtg gaatgaatta gttagttttt
    18721 ccgaaaaaat ttatgatatt acgcaagaag atgagtgtgt ttcatgggaa atgaataatc
    18781 aatacaagaa aattgatgct ttcgtcaaat cacgtataga aggaacagct tttgagtttg
    18841 aaggtataga taccgcagat aattggttaa ataaagaatc ctttattaaa agtatagcgg
    18901 atgatcttga aaaacaatgg tctaaggaag actatgcaga gtacctaaaa acagaaagag
    18961 atacagaggt gaaagaaaaa ctcactgagg tatgtttgga tgaacatatt gatcccaata
    19021 tcgtaaaaca agaagactat gaagtggtta ttgataaagt tcctactgat tttgaggaag
    19081 ttgtaaagta tatagttgaa gaagcattat cgcaatactc ttcagatgag gaagtggacg
    19141 aagaaactgt tcgtaccaga gtttggcaac tggtttttga tgacaaagat tataaatatt
    19201 tgagtgatca aaactcggtt aattggagtg tacgattatt aattgatcaa aatgatattg
    19261 aataaaatag agctgaaaag ctctattttt tttgataaaa aaactagcta tttttttaaa
    19321 aataatttgg ttcaaaattt atttttttaa cttgataatt ttttgccatc cttttttaaa
    19381 ttggctatat atcaaggttt atagtgggga taaataaaaa tacatttgac aaaatttaca
    19441 atatagttta ttatatattt atcttattat gataacacaa taaaaggaat gatggtatga
    19501 aaaagaagaa gtttagtcga tcgttgttag gaattttagt tttagttgcg gttggtctta
    19561 gtggcaaggg ttactttcag aataacagca ctcaggaaca tgattttcag atcaaaagta
    19621 gtgttcaggt aggtaataaa gcagacagtg aatcaaaaga atttttaggg atacgttatg
    19681 atccaaacaa atatccaaat aatatcgtaa acattaatga tgggaaatat acactgacaa
    19741 aagaagacca tgaagcatta tcagaaaaag gcagtcaaac cttttgggta aattatgcag
    19801 atttagatca acttggaaga gcaggagatg ttgaagcgtt gatcacctat gatgctataa
    19861 attctcactc atctaaaaat gtggaacgtc catctttcaa aagttctgtc catattgcag
    19921 gagaatacaa ggatggagta tttgatcaag agagagatac ttgggtcggc aaagattcaa
    19981 acaatgaaat cactcagcta gaaggatata aaggttatct ctataacaaa agtcattcat
    20041 tagcatggtc gctaggagga gatatggagg tacacaattt aacacttgga acgagagcgc
    20101 aaaatgttgg gaaaaatgat cagaatggag ggatggctta ctcagaaacg attgtacgtg
    20161 atgcaatcta taaaaataag aatgaaaaag tattgtataa agttgatcca atttataaag
    20221 ggaatgaatt ggttcctcgt ggttctcatg tcgaagcttt ctcagttaac gataatggaa
    20281 aaacggtaaa ccttaatgtt tatgtattta acaatcaaaa aggaatcaac atcaactatc
    20341 aaaatggtac ttgggtaaga gattagaaat tgagaaggtg aagaattgga aacaataagc
    20401 atcaatggat tagataaatc agttgcaaat cgaataaaaa aaggaaatgg ctactatctt
    20461 ctgaagaagg gtaaatattc agttgctaga gagttagaaa caatgagtat cgtgtatgta
    20521 gctaagaatc attttgacgt agaacaggct atttttgatc cagattctga aatagggaaa
    20581 tgtgttgaat tatcagagaa aactgttagt acaaaagggg cgatgatcat tgagagagaa
    20641 atgttagacg aaatcagagt aatcattcct aaagatacgc agatgtgtga ggacagcata
    20701 agtgacgatg aaccaaaatc agaaagaaaa taaggagata ttcagatgag cgaaaaatcc
    20761 attgaattaa aggaatataa gcgaagcgat ggagaaaaat attatcctgt agccagtttt
    20821 tctaaatcag tatatctggt tggacgtgca ttggtagttg gtgcaattgg catatatatt
    20881 ttgcattggg taacaaaggt tgtacaactg cttgtagata ccttagtaag tattcttgtc
    20941 tcgttaaatg atgttaacgg aacagatgat ttaggattaa aagaaatgtt taaagagtta
    21001 ctcaatgcgt tttttcccaa ttatttaagt tattcatata atgtacaaag cttttttgca
    21061 aagctacact tggtagacat ctctatttta gtattagaag caggaacggt attctttgtt
    21121 ggatatttgg ttactttgat gttcaggcat cactatggag aacaaagacc attttttgat
    21181 gatatggaaa gtagaaggtt gaaaagagaa gctctagaag ctatggatgt gaagtatgat
    21241 ccaaacaaga ttataggaga tgaaacgaac aacaaaaaaa gaaaacgaaa caaaacgcaa
    21301 ttagaatccg atgtgctatc aacgcttaaa aatatcaaaa tttctgttca tacaagacgt
    21361 gatctaagtg tcaatgaaga tattcgagaa tatatcgtaa aaatcccgca accaaaaggg
    21421 aagaaagtta gagaaacagt tttacgacaa attcaagatt tagggtcgat cctgacaaga
    21481 gcaacaagcg gacgagccaa atttggtgaa aaagaagatg aagtttcagg cgattatttc
    21541 attttccgag catcagtaaa tattgaaaga gaacgtaagg aaagagtaag taccaaaaac
    21601 aaagaaacgg aaagagcaac atcttcaatc gcagtttcaa attcacaatt ttcttttcca
    21661 atcaatctct ttgccgataa ttccaaaaat atccaaaacc aaaccgaaaa agctagaaaa
    21721 tatgccgaaa ctcaaaagca atctttagaa ctttatctat cttctgctga cgtacctgca
    21781 agtctaacag atatgcacgt tgggaataca tctattgaat atttgtttac tttatctcgt
    21841 accagaaaaa ttcaactaag ctcaatgaaa gaagaaattg aaacttactt gcatatatca
    21901 ggtgtaatcg tgcggatcaa cgcagggcgt attcaaatta ctctaccatt aggagaaaat
    21961 gatcgtattc caattgatgt accatcaatg atcaatagcg tgttttaaaa gacatcacaa
    22021 atagaaacag aaaatacaaa ctaccagttc acaaacagaa aagtaccgag aaaagtgagg
    22081 aatagaaatg gctatgaaat tattagagaa agtcaaaaag agagccgaaa aagctgaatc
    22141 tattttgcta gataaagaac ctaatataaa gcttaatgga aaattcagtg tcaatatgtt
    22201 gaacacaaag gctaaagacc cgacagatgc tatttttgga attaagcctg atggcacaat
    22261 tgctcatttt tgcatcagcg aaatgccaca catgttggtt gcaggaacga caggatcagg
    22321 gaaatcagta ttactgaatg aaattcttgt tacagcaatg tgtcactcaa cgcctgatga
    22381 attaaaaata ggaattgtag acccaaaaag ggttgaattt ggaagataca aaaaattgcc
    22441 gttcatgttg gctgatccaa ttacagatat ggatgaagct tatgattttt ttgaatatct
    22501 tgtgatcttg atgcatgaac gttacaaact gatggaaaaa gcagggttac aaaacatcac
    22561 gctatataac gaatatgccg aaaaaaatgg attagataga tttccctatg tgatcttatt
    22621 agttgatgaa tattcacagt tggttggaac acataaagaa gtagaaggtt tgattgttca
    22681 attaggacaa atggcaaggg cagcaggtat tcatgttatc ttagctacac aatctcctcg
    22741 atcaacagtt gtcactggta ttatcaaagc caattttccg tcacgtgttt gccttatggt
    22801 agcaagtgat ttagaaagta ggatcgtatt agatgaaggc ggtggagaaa gcctaagtcc
    22861 aaagggagat atgattatta agctcgttaa tggaagtatg gttagagcgc agggagctta
    22921 catcagtaac aaagaaattg aaacaatttt caatcacctt agaaatacta tgccagaacc
    22981 agaatatgtt gattaccgag caatcgtagc tgaatctcgt ggtgagggtg gagaagacga
    23041 ggattttggt ggaattggta aagctcctgt aagaaaatct gctaaaagaa atttgaacac
    23101 acctttagca aattcatcat ctaaagagcc atcaattgaa aagaagagta cgtttgctct
    23161 aaaacttgaa aaaaacaaag aagaaaaaga aaaacaagga gctaaaacac tagaaaaact
    23221 tcaagccgaa aaattagaaa aagttttaaa agcattagat aaagctgatt ctgaaccgca
    23281 aacctcaaac aacacgaata atgaacagcc gatttcatct aaaactaaac cgaaaactac
    23341 tgatccgaaa gtttcagtaa acgtgaccat cacaaccgat aagtctgaga agaaacaagt
    23401 aaacggaacg acttcaccta tcatgcaaaa aatgttgaaa gccaaaaaac aggtgcataa
    23461 atgatcattg tcagttcttt tttgaggtgg cttacgccat ataaatatac agatgaagta
    23521 gttgtgaaac gaacgaagaa aagagataaa aaagcggtac taactcctaa acagatgctt
    23581 gatcatggca ttttaggggt gaaggtttta gaagtgaata aaccgtttga atcaaatagt
    23641 gcaagagaaa agttgcttgg agctgaagcc gatgtcgcat atttttacca tgacaaaagc
    23701 aagcatcaaa tagctattaa attcaatcca aaatcggcat ggcggtatca agcaagagat
    23761 gacttgaaac gtaggaaact tagaccaatg ctctatccag aaggaaaaga agcatttgat
    23821 agaacccaca tcgttcccat tggttttcat ggtacagaat cagataaccg cctattagta
    23881 ggttggaaca gcaatcaaaa tagagttcag atcaataaat ttgagaagaa agtaaggaaa
    23941 ttcaacgatc gaaaaacgat cctatggttt gcagatattt gtaaacagcc ggatggaaca
    24001 gcaaagtggg aagcggtgat atttgacgaa aatggtaaaa aagtaatgtc tgaaacatgg
    24061 catgataaag ctaaatttgt ttggcagtag cagtagaggt gaaaaagatt gctagaactt
    24121 tttgaagcaa atagaacagg ctttaatcaa aagttagaag tgggagaaac tatagaatat
    24181 aaagataaaa actatattat tatcggaatc tataacacga gaattaacag aataggtgat
    24241 ccacgtataa ccagtgactt ggtttgtcaa tctgttaact attcacctga tctgacaagc
    24301 aggtataaga aatacgtgtt attagaatat agacacaaga ttactgatga aattggtgta
    24361 aacaacacac gaaacatatt taagatcgga acagtgattc cttatagtaa caacgaagaa
    24421 aaaatatttt atcagattta cggaatagaa aagtttgaat atgaacatgt cgatctgcta
    24481 gtgacgtacc aaatgcgttt aatagaacct tggtcacagg cagaaattga taaagcagta
    24541 aaattgaacc gattatcaaa atttaacgta ttaggaaatg ccttttaaaa atcgcaatac
    24601 acaaacagaa aaataccaaa aaattagcaa tgaacgtagg taagaacatg acaataaata
    24661 ataataaccc taaaaaatat aatgctcttg tccaatgcta tatcgaaaac aaaattacaa
    24721 tgcaagaagt cgctgatgaa ttaggcaaat caaagagcct agtatcacac gattttaagc
    24781 acaatgtttt tccgaacccg attgagctga ggaaaaaatt tcaaaagaga gtttatcaag
    24841 aaataggtaa gtggattgat gaagggaatg caattgaccc tttaattgaa aaatatcctt
    24901 ttttaaaaag caaaaataaa attcaaaggt taattcgtca aggcgatatt caagctaaag
    24961 aacctgtttt gacaaccaat gatttggcta aaataaatct tcataaacaa attattgaag
    25021 actttgaaaa aaatctttca acaactgaaa ttttaaaaaa atacaatatt ccgagaggaa
    25081 agctaacatc gactcttttt agagaatatg gagaatcggc agttactaaa gcaaaggaag
    25141 tagcgaatga gagaaaaaaa caaaaatagt agtcgatacc tagtagcgac tgtagttttt
    25201 gtttgtgtat tgattttcct gtttgatttt ttgcagattg gaaaaagcat aattggaaat
    25261 acattgagtg caaaggaaat ggttgcttta ggtggtttgt atgaaggaca cttgttcccg
    25321 aatatattca tttctatcgt ttctcatatt aacttgtacc atttaatttc taatttattg
    25381 ttcttagtag ttcttgaaga agcactgaat gatcagtatg agtggttaac attattgatc
    25441 gttttaatca tatcaggatt tctaggaagc ttagttcctt ttctgctaca cagcaacatc
    25501 gtaagtatgg ggcttagtgg aggtattttt ggatggattg ctttatttgc gattgcatac
    25561 atccgttttg atagcaagaa acatttatta ctaagtgttt ttgtattatt gataatcggc
    25621 attttactgg tatctacttt tgaatcaggc gagacaaacg tcttgtcaca tgtaatcgga
    25681 tttgtctgtg ggatgatctt gggatttatt ctaaagaacg tttcattgat caaacaaaag
    25741 aattaaaagg gagtgctaaa aatgccaaaa aaaaaagaaa agaaaattcc agtgtttttg
    25801 tctgtctcag aaatgttatc acttcaaata ctgttaagaa aaaagattga aacaatagac
    25861 gaagaagtta gaaataaaag ggctatgtac gaacaacgtg aagcgctaag agaacgaatc
    25921 cactattttg atgatataca cactaaaatc tatgaagcac gtacaaatca cgaagacgaa
    25981 agcaaattag gattagctca acaacgaata tttgaatggc tgaatacgaa tactgagcaa
    26041 gaaccgttaa gagcaattag taatcttttt gaatttggaa cgaagcattg gtttaacgct
    26101 gtagaaaagg atgctgactt acaagaagcg ttcgatacac taagcgagga tagcaaatcc
    26161 atgcgagact tattgatcac ttatctaaat gagcatgaat ttgaacagac gaaagttaaa
    26221 aagaaaaata aaaaatagaa agttgtgatg tatcatgctg tttaccttat taggttattt
    26281 atgtttagtt cttgcttttt ttggagcaat tgctatattt gtcggtcagt ttcaagaaaa
    26341 taatccgata atgcgtaaca taggcattgg aattgttatc atatccttga ttgtatttgg
    26401 tgccacaaag atttttggga gtaatgatca gcagtttggt atttctggag ttgataatag
    26461 ttatgctcca gattcattgg gaagagtagt gatagatgga acgtttgaga atgtaacgag
    26521 ctacaaaaat gtttcattga cagtgaaaga agatgacaag aaagcatcag atgacgttct
    26581 cgctacgatc aagccgtctc aatcacagtt tgaagtgttt tatacagtca aagagaataa
    26641 ccctgtacgc aagctaacat tagtttttaa cgttgacgga gaagaatact ataaagatgt
    26701 aaaaatcaat aaagcatcaa cgaaaaagat tgtcgaatca gcgaaaaaag aagtagctac
    26761 agaagaaagt acaactgaat caagttctac tgtcgaagtt gaactaccag ataaaattga
    26821 ttttgatcct gaaaaagtca aatcgtttga atctgtttct ggttctatgg cagatcggtt
    26881 taacactgaa gttttcaaag ctatcaaaac tgttaaattg gatactgaaa agcaaaggat
    26941 taatgttacc ttattcaatg cagttgaatc tatggatcag gataaaaaag ttacggttgc
    27001 aagagaacta gggaaaagag taattggatt gtatcgaggt acggcaaaac cagattcaga
    27061 cggttcagat ttgccagttc acgtagttta tgaagacggt aaagtttttg gagactctac
    27121 agcaaatgaa gcactaacga ttaaattagc taaatagccg gaaaattata ataaacaagt
    27181 ggtgtcacac caccatcgca taggtgtgac accttggaga tgattactga tggtagtaaa
    27241 taaagaaaaa gtaagaaagt atgttacttt aaaaatagct tctgttgaat atttagaaaa
    27301 gcgagctaaa gaagaagaaa aaaaaagagg taagaaggta acagtttcag agttgttaga
    27361 agaattaatt gagagtgacc aaacaataag acgtgcattt accaataggt ctgttaaaag
    27421 ttagggtgat actatcttta atttcaacca aatttctaat atatgatgaa tagtttcctt
    27481 gtacaaaata tctaattaag agataaaagt taggaggatt cattcaaaat gattatccaa
    27541 aagtttgact ggaaaatgaa attaggaatt agtcttgtaa tattgggatt tattattttt
    27601 ttggggataa aagcacaaaa aaatcaatct acttttgaaa ctatgtcttc tcaaattatt
    27661 gaggaatgtt ccaaaattta ttattgtgag aacaaaactg aagaatctaa tggcttttat
    27721 tatatcgatc aaccacatga tgttgttata aaaatggagt cacatgaagt aaacgaatgg
    27781 attcaaagaa gtactaatgt atcaaaaaag ttagaaagat attctcaaac gtttttaagt
    27841 aaagtcattt tttcaaattg caaaaatgaa gaaacgtctc aaagagtagc tagttcttta
    27901 gaaaatttaa aattttctgt ttcaaaaaaa gagaaatttg tagatttacg aaaataaact
    27961 atcgaaagta gtatgattat gatcttaaaa tatcatctta agagaagaat tacgattgtt
    28021 tataggattt acaaaatgaa taagtttgaa gagtgatttg gtcgcagact agatcactct
    28081 ttttgtgtaa aaaaacttta cacttatttt tgagtgtgtt aagatttttt atatagagtg
    28141 acggtttctt gtcagagtgg atgataacca tcaatattgg aggaataata agtggaaaac
    28201 aataatgata ttagatattt tagcattggg gaaagagtta caacagtaag tgaattatca
    28261 aaggattata gagataaaga aggaacgatt atttctctta aaaagaatcg aagaggtgtt
    28321 tggcaatatg ttgttgattt aggggatggc gttacagttg agtgtaaaga tagtcaactg
    28381 atcagaaatg atggcagtca ttccattgaa aaagcaattc ttgtattccc aaaagtatca
    28441 agcaagatta tgaatgactg gttgcttgga aaatttggtg agtacaataa aaaagaaatc
    28501 gcagaagtga tcggcaaatc ttatccaaca gtattagggt atctaaaaaa gataacgaac
    28561 aaagaagcga aagttgagga tgttttaaca gtaagagaac ttcagtcatt aatcgaatat
    28621 cggaataaac aaataacaaa tcctgagtac cttaaaaaag aagatggtct attgaaacaa
    28681 ttggaacagg taaataaaat ccggaaaatg caaaaggtag ctcctttaag cctagataac
    28741 tttaaaaaaa tctatttgaa agagatcgaa aaagactaat gtggagtgtc actttaccgt
    28801 ttcaacctgt atctgcacca agaccaagtg caagaaggaa tgttgctgat gcaactaatg
    28861 acgtagcaga gaaaaggatt tcaacctatt atgataaaaa gtatctcgat tatttgaaaa
    28921 aaataaaaag ctttatcgaa gatcaaggtt tgttagatga tgaattttac tcgatcgtaa
    28981 atgatccgat gggtgcaatt atggaagtgg acttttacta tcagatacca aaaagctata
    29041 aaaaagtcta taacattatg aaaacgacag cgccagattt agataattta gtaaaaagtg
    29101 ctatggatgg tattttcaac atctcagcta tacgagatag ccatatcaca gggttaattg
    29161 cttttaaata caatgtggca aacgaaggaa aaacagttgt gaggatcaag cgatattcag
    29221 aatttgagtg ggatacttct gaaggattga acggagatat ttgggaagcc acatttgatt
    29281 tcaaaccagt agcaacgcca agaccaaagt ctaaatttag aggaaatggg attatcactt
    29341 actatccaaa agagtataac gactatttgg aaaatatcaa gaatacgctt aaagagaaag
    29401 atttggtaaa tgatcaactg aaaaaggtaa tgaatgctcc tatgggggtt atagctcaga
    29461 tagattattt ttaccaagtg agaaaagata agaaaaagct tgattcactg atgcgtactt
    29521 cacagccgga tattgataac ttagtcaaag gaacattgga cggaattttt aacaaggaaa
    29581 ttggcatcaa agatagcagg gtggtaggtt taatagcttt taaatacaat acttttgaaa
    29641 agtcgaaaac aaacgtgcga ctacaggaga tgggctgatg aataataacg aaaaaattct
    29701 tcatgtactt gatagctttg aaacaattca agaggaacta aagaaatatc gagatgtttt
    29761 ggaacaaaga tatgattttg tcaatcagca aaagagtaat cacatggatt tcattctcaa
    29821 tatgaatgac ttgaagaaga aattagttga acgaaaagaa caagaaaagt tgatcaaagc
    29881 ttactttgaa ctcggtgaaa aagaagttaa aaaggcaatg gaactgaatg aagatcgcag
    29941 ggttttagat cagctgttag aacaattatt ggtgatgttt caaaaaggac gaatagatga
    30001 ggatttaatt gaagaagggt tgagaaagta tcctgcaaac tcaggtatcg gaatagtgct
    30061 gaaagcgatt gatgaagaag aaattgaaga tttcataccg gcagaggatt ttgaatcggc
    30121 aatggaatat ataaaatatt acagccaagg gatcactgct tttagagagt ttgatcctga
    30181 agatgttatt catgacttga acaacctaaa agaatggtgt gaaggttatg aagttgatga
    30241 ttccggtttg gactacttga tcagtattat ggaaatcgaa gaagagatgc cggataagcc
    30301 tgatccaaca gatattttag aattaatcca tgatgctaga aatccaattg catacatttc
    30361 tagaggatat actgtattgg aatactataa gccttatata tcagcgatga accatttaag
    30421 acgtgtatta agggaaaaac gtgaataccg ctcagtgtta aatgcatcga atagattaga
    30481 aaaagctgtt tcagagctag atgcttatta tcgtgaacat tacctgcaag caggtggtat
    30541 gccaagaaat acgaaagcaa atatcagtag gtatataaaa gaagctgagt aggcggagtt
    30601 agcccataaa atggcaaaag gtaacctgaa agaggcgttt tgaatgaaaa gggatgtttt
    30661 tgaattgtac gtattagaac gtctagaaga cggcatgatg gcacaagaga taattgatga
    30721 aattgatgat atgatcagca gatttggtca attggaattg aatgatggaa acaaaaattc
    30781 ggtagtgcta caacaatttt ggttaaataa tttttcgtat aaggatttta tcaaagaaaa
    30841 ggcaaataga ttgtactgac taaattcacg aggatcagtg atgagagctt attgctaaga
    30901 gcagttaggc tcttttttgt ttgtgttaaa ttattttatt ttacaataca catttataca
    30961 caaaaaatgt tgacggatag tacacaaatg tggtaggata tatttgtaag caagttagat
    31021 taacaagtta aaggaaggaa gagcagttat gaaaaaagaa gaactaatag atatgtttca
    31081 aattgttgaa cgagcaaata atatgggaat tatgtttttt gatcgtattt ctttaaagat
    31141 ggatttaagc gttgcccacc aagaatttaa tctacgatta aaagctttat tgatttctga
    31201 tgatgttaat ttcgctcatg atgttgtagg tatacagaac catatagata gagaaaacaa
    31261 acgtatgggt gatggattct taccaagata ttcaagttta tgatttggcg aaagattcaa
    31321 gagtatgtgt cattattgat aggtactctt gaattggaaa ggaggaatga atttaagaca
    31381 acaacgatta tgatcttaaa acaatcgttt atgtaattgg caatcttacg aataattttc
    31441 atgcaataat gacaataaaa aatgaaaagg ggtaaaatca aatgaaaaaa tttttagtag
    31501 gaattctatt cacaatgggg ctagtgctat tatcaccttc agtttcagca gaaagctcta
    31561 tttccatgta tcgtatgtat aatcccaata gcggagagca tctatacact agaagcgttg
    31621 gagaaagaga caatctgaaa cgttatggat ggcattacga aggtgtcgcg tggcaagctc
    31681 caacaagtgg ttccccagtt tatcgcttgt acaacagata taacggtgaa catttttaca
    31741 ccgttgatgc cggagaaaga gataagattt cgcacacagg atggacgtac gaaggtgttg
    31801 cgttctattc ctacaacgga gcaaatagag ttcctgtgac acgcttgtac aacaaatacg
    31861 tgaattggca ccattacacg ttagatcaaa atgaaaagaa cgtaattagt aaacaaggtt
    31921 ggaagattga aggtacgggt tggtatgcaa tgccaaacag cgcaccaaat cctacacctg
    31981 cacctgctcc aagtaatgaa aaagtgttaa atgttcctgt catttggcaa ggtaatacga
    32041 tgttgtgtga aggtgcttcc ctgttagagg gattgcacta caaaggagta gcgacaaatc
    32101 aaaacttaac cagttttgta aactatatgc caagagctaa tgacaataat ccatatcatg
    32161 gctattctgg cgaatggcgc tacaacgtaa atggtacgta tcaaggcatg atgcctgatc
    32221 cagtagttaa atgggcaaaa aatgttggtg gtaatgccgt taatatcact ggttcaggaa
    32281 cgaatgggat caagaatgaa attcgcaatg gtaatccggt tgtaacttgg attacttata
    32341 actatgcttc acctcaattc aaacaaatgc cttggggacg tgcagtctgg aatggacatg
    32401 tggttctcgt ggatggcttc aaaaatggtg cataccatgt tgttgaccct gtatttggcg
    32461 caaaatggat caatgcaagc acgtatgaga gagcatttaa tgtgactgga atggcggttg
    32521 ctgtacgtta attgatagaa ttaataaata aatgaaataa gagcttaatt actgaaatgg
    32581 taaatgggct cttatttttt agaaaaaaac tgttttttgt aatacgaatt tataacaaaa
    32641 aacgttgaat gtagtacaca aaagtggtat attaaaaccg tagagattat gcgaagaggt
    32701 gattttgatg aaccaaagaa gaagaaaaag gctagaagaa ataagcgagc gactatccga
    32761 gttaaaggat gagttagaag taattcaaga agaagaggaa gagtacaaag aaaatatacc
    32821 tgaaaatcta cagggatcag aaagatatga aaaagcagaa gaatccgttg atcaacttga
    32881 agaagctgtt gatggtttat ccgacatatt agaattgatt gaagatatag ctagctagag
    32941 atgattaatg aagatttcag gagtgagcaa aaaatgattg atatttcact gatagagaag
    33001 ctactttttt caaataagta cacagccaaa gagttggcta caagatggca aatatccgaa
    33061 tcagctatta aagcctatcg tcaaaataag ggaagcgtag gatggcgtga ttggaaagga
    33121 atcagcattg gaaaagcaga agacataatg aaacgtgaag gatttcaagc tgacaatgat
    33181 tctaaaaaag ttgaatagtt taatagtcgc caagaaaagt accaggacga ggggaaaggt
    33241 agattacaaa ggaaaacact tttaaataaa cttcgcaaaa gcatcaggtt atgagtggct
    33301 agggctatac gaatgtgatg aaaacaaagg gctttaatgt caaagaaaac gcaatagggg
    33361 gggaacaaaa tttttaaaaa agatatttat gtttggttta atggaaaaaa atatatgact
    33421 actaacaaaa ggtggtcaga gctagtacaa aatacagtta aaaaagtcat gccagatgga
    33481 tatcatttca actatataca atgctcacaa acaactgaaa gtatttattt ttcaatatta
    33541 aatgagaata gactctatta tttcagggta agttcacacc ataggaaaaa gagagaagat
    33601 aatgttacga catttttatc gggaaaatac aatggcttca aagagttaag tgaagccatt
    33661 ggtgagtatc taaaaagtaa tagatttgtc agaatttctg acaaacatat attgatcttg
    33721 ttactttatt tgaataatag cttcaaattg ttttggagag acgacacttt ctactatatt
    33781 gagaacggca tggatattta ttctggtatc aacggcatat taaaacatta tattaaggcg
    33841 ttacttcgat atggggttct ttatcaagaa gatttaagta accaaattaa gattagtaat
    33901 tctggaaagt cattactggc aaaatataaa aaattgcttt ctcctatcta caaaggaata
    33961 gatatggaag ctgtaaattc tgaaacttta tttaatttag ttgttgatga aaagtttgcg
    34021 aatgaatttt ttaaaagtaa aaaaattgaa agactaaata acctgtttcc tgaaaatgca
    34081 ataaaagctt atgtagataa taataaatca cgattataca actggtttat tcccaaacgg
    34141 ttgcgaggaa aaatcaaaat tggcgatcaa gtgaaagtaa ttaatctaaa tcatactaag
    34201 atcgttaccg taacggagtt gtatatagct gaaaaagaag atattacaaa aatgaaacca
    34261 gttattaaaa tactagataa caaagagtga gtggaatata tggtagcaaa aaagaatact
    34321 ctaaaagaag cttctgaaaa atatcaagat atgaaaagac gaggattaat accaaaggac
    34381 aaaaaaggta tatggagaga atttgttaag gaagtcagta gtgatcgaag tggcggtgac
    34441 tttgttggac gatatacagc aaaaggttat agcaggcgct taaggatcac tgttgaatat
    34501 ggaacgaatg aatcagctac agagctgaag caaaggtact tagatacacg aagagaagct
    34561 tcaaaaaaat atgatgattt caagagcaga ggtctaattc ctaagaagaa aaaggggatt
    34621 tggcgtgagt ttttcaaaga agaagatagc aatcggaata agggagactt cattggacga
    34681 tacacagcaa aaggctacac taagaattta gggatcaagg ttgaatacgg aactggtgaa
    34741 agttcatggg aattgagaaa tcgctattta aatacattgt tagagaaata taaagcagaa
    34801 ttattggagt tgttcgatgt taatgatttt atcgagatgg ctgaaaagta tggtcatgaa
    34861 gaaggtttta tgatcaatga cattatggtt attgataatt ttacggattt attagcactt
    34921 gcgaaaaaag caagggattt aagagaaacg cagatgtatc tattcagaaa taaaaacgga
    34981 agaaaccgga gaactgaatc gagtgagatt gaagattact atgatgcctt tacacacgat
    35041 ctgggagcct ttgtagacga gataagtggt gtaatgaaca aatatagggt ctagaataaa
    35101 aaagccggag atgagcagat aaatgggaaa caatagcata tacacacctg aaatgcagaa
    35161 taaaattaaa agacttgtcg gattagggtg gatgacaaga ggaaaattag attcttttag
    35221 tacgatcaaa tatcttttga tggacattta ccgtcagaac aagcaaacag gaatacattt
    35281 tttgggctat gataagccgg aagatgcacc tttctttgtt ccaagttcag cctatagagc
    35341 cagtacctcc ggtagcatgt ataacttgga tttgtttgag gaaggagcaa agatgatcga
    35401 atatgatttc aacgaagcct attcgaggat catgagaaat tatcctttgc cgtcaaacac
    35461 ttatttgaaa gcaaaatata atacagatca agctattttg agagcgataa atagaccaaa
    35521 agtaagaccg tatgaaaatt taaaaacgta tatgttcttt ttggttaatt ttgaaggaac
    35581 agccaaagaa ggaacatatg ctaatccaaa atcacagtcg atgtttgcgg attatggcga
    35641 aaatcccaaa acagctaatg agcctatttg gttatcggag attgagctaa cacttatcct
    35701 tgattattat gatattaaag agatggaagt cctagatagc cacacatttt tgacgaaaaa
    35761 aggattactc aaagaatatt ttgaaagaat cgagccatta aaaactgatc ctgatacgtt
    35821 gaagctttat aaaaatctta gaacgaaagt atttggtgct atcggacaaa aatcattaag
    35881 agaaggagaa acaagcacct tcgataaata cagtatgtat aatcgagcgt attcctccat
    35941 ggtagcaggc gtatttagag atcgtatggt tagatatgaa cagaaatacg ttcatagcgc
    36001 atatgggcta ttaaaaattc gtactgatgg attgtatttc agatccgaag taccagagtt
    36061 tgaagagctg tataaacttg gagtagttaa gaaaaaagtt catacaatat ccaaagaaga
    36121 agtcgaaaaa gctttagaat ttaaaaacaa aggatttgaa aataagggct cctttgggaa
    36181 atctaaagat gaagttaagg gtgttgtgat agacgatgat ttcgagtttg attttgacta
    36241 aatactcttt ggaaaagatg gtaggaggta aatatgaaga agaaaattgt ggaaggaaat
    36301 gtaggtgtta ttattctaaa agattcaact gactatgcta aatcaatggc actaaaagac
    36361 gaaaaagttg cacgcatgga taaagattta gttgaatttc tgatggatga tacagaaaga
    36421 ttaaaagggg atcagttttt gagtttaatg aaagacaaag gcttaaacac atatggttta
    36481 tttgattata agaaattagc tatagagtgg gtaaaagaag gagaaatatt ttttattgaa
    36541 gaatgggaag gtactgagaa cttagttctt catcagtatc ttttgaaagc ttaatctaag
    36601 taaaacagtt ctgactagtt atgcttgtca gaatttcaaa ggaagttttc cataaccatc
    36661 atcattcaaa aataaaggat ttgaaaataa gggttccttt gggaaatcta aagatgaagt
    36721 taagggtgtt gtgatagacg atgatttcaa gtttgatttt gactagattt ttttgcaatg
    36781 tttaagagta aacaaggtaa gaactaagat catgaagatt gagagtaaag aagatagagg
    36841 acgaatgtat gagaacacac tatatttatt tagaagataa aattgtagat gaaattccgg
    36901 caaaaagtcg agaacaagct agaaaattat ttattgaaaa atacaaagag atcaatggag
    36961 atagtgaagt tccaaaagtg gtcgtaacag ttagaaaaag gcaaacaaaa aagagaagta
    37021 cgtttcatgt cagccctgat atatataatc ttatagagcg acatagaagt gaagataata
    37081 tttctatctc tcaatatatt gctacagtta ttgatgaatt gatttcagga aagtatgact
    37141 atgcttttga ttttgagggt gaaaaggatt acaaaagtgt tgctgtcttt caatctgatt
    37201 ttgagaagct aaaaaactat gctggcagga gaaatgttaa ttttgcaaga ctactagaag
    37261 agttctactc cgaagagttg ggagtaggaa atgaatacaa gagagaaact tatgcgaaat
    37321 tgtctcataa gttatcccaa gcgcttaaag aagtgacaga agttaaagcg gaactagatg
    37381 ctaaacttga agaagtgaaa aaatatcaaa cagagaggaa gaacaacatg aagaatcaag
    37441 tggaatttga cgaacagaaa gaatttgaaa aagcaagaaa acgctataac aaaattatga
    37501 atgaacttag ctatgaacac ttaacagttc atgaataatt gagtgagggt acagaaaaat
    37561 atacgatcgc agatatggtt aatgaagtgg aaactctttt agcttctttc tttgaaaatg
    37621 gtcacgtaaa cgatgaatgg cgaaaagaag aacctaaaag ggttaacgct tatattgctc
    37681 gattaaaaag gtttattgat aaatataagg agaatagtga caaattttct aaagataaat
    37741 aaggagagag tgtgattaca tttgccagaa atcgaaggaa tattttcgcc aaaaataggt
    37801 aaaaaacagt tagatttcag cagttttccg agcgtaaata gagattataa tctaggtgat
    37861 gaggtacaga tactaaatat tgatttcaaa gaactagact tcgctgttgc tgtttccaac
    37921 aaacccaagg cattggaacg agtgaaaaaa atataccaag agaatgatca aaatatcaaa
    37981 aatatgatca aaaagtatag acgagataat tcaaaagttg aagacgtttt attcaacggt
    38041 acggcaaaac atgatttgaa tgtttatatg gcattaggag tggctttgta ctgtaattca
    38101 attaatcaga cagatatttt ggttaatatc gtgaggaata gctatcaaaa aatattaaaa
    38161 ataagtagcg aaacaaaccc ttattatgca atgaaatatc ttggggataa tttattaaat
    38221 gataaaaaat tgatgcacaa cactgaagag ctgttatcta atttggctgc gattaacttt
    38281 ctattcaaaa caggttctga agattatttt atagataacg tactaaaagg tgcttacgga
    38341 acagcatttt atccgcttta caatatgaaa cagcataaag ccgaacaaaa ggataacaaa
    38401 cttgaaatta aaaagatgaa agaactatta ggtataggat ttgtaaaacc caattcaaaa
    38461 gtcactattg cttcgttagc aactactaac aatgatggga aaatagtaaa tgggtttgac
    38521 gattcagata tagatatatt gtcaaaatca tatttttctt tgtatggaga ttttgcagat
    38581 ttgatgggta ttgatagtta cttagtcaat aattttgaga tcaagggtag cgagctgaat
    38641 gatattgtgt atttcgtttt aatctctcta tatgcaattg atcagaatac cgagtaccga
    38701 caaattgact atttgctagt tttttatagt ttgttatatc agttcgtttt aactcggttg
    38761 tttaaaaatg ctaaggaaga attgatcctg aattctgatt atgaaatagc aaaacaaatt
    38821 gcaagtatta gaaaagaaaa caaatctgaa gtaatcaaat taagaaaaga attaagtatt
    38881 gcgagtaaag aaaacggtcg gttagaatct ttagtcaaat cggcaaaaaa agaagaggaa
    38941 cttttgaagc aagagattaa agaattaaaa ggaatcagaa aagaacttga acagctgagg
    39001 tttgaaaata aagtattaaa gcaattgcag gagcaagaac atagacaatc attaaatggt
    39061 aaaactgaag agccttcact gtctgaaatg atagcttatc taaaacataa aaacattctt
    39121 ttagtgggag gacatgtaaa ttttcaaaat aaattaactg aactattacc aaatattaaa
    39181 atgtttgatg taagcgaaaa taatggaaag atacttaaaa atttgaatac gtgtgatgcg
    39241 atttttctat atacagatta cttgaatcat ggtctatatt atcgtgttat gagtgaaatt
    39301 tctaataaag ataagatatt ttatttggat aatcatgtga atatgaactt aacaattaaa
    39361 cgtatttacg atcttttatc acttatataa agagagaagt gataaatagg acacaaaatt
    39421 tggaaagtag gtaagtcact atgagagaac taactttatc ttctaaggaa ttagaaaaga
    39481 aaactgcttt attaaacgaa atatttagtg ctgattgtat aatccaaagt ttaaaagaaa
    39541 gttcattttc aaaactaaca gatcaggaaa aaatttctta tatgctaagt ttagataatc
    39601 taggaactaa atatgatgaa tcagcaagta gcgataagct tttgattgaa ttagtatcaa
    39661 gtcttagtag ttttggaaaa atgaaaagat ttaatgtgat attagaaatt tttgcttggt
    39721 taatcccttc atttatttgg tttttttata ttttcatagt tgaatctgag ttaatagcca
    39781 aggtctctct tggactgtta attccgatat aaataggttc agcaatttac tttaataact
    39841 tgtatacacg tattcaaata aaaaagcagt tattacatga aggattaagt ggtaatatgt
    39901 taaaaagaat tgcatgggat aaagataata aaacagatat tgagcttaaa gaatataaat
    39961 acaattattt ctcgagatgt atagatagaa agttactgtt taaaaaagaa ggattagaat
    40021 ttagttttga tgaagatgaa tttgaaaaat tagtgatgga ctggcgtaag aatttactgg
    40081 atacggtaca attctaaaag caattgaggt cgaaattccg atacttgaat catgatctat
    40141 attatcgtgt tatgagtgaa atttctaata aagataagat atttcatttg gacagtcatg
    40201 tgaatatgag cttaacaatt aaacgtattt atgatctttt atatgtttat aaacattaat
    40261 gaggtgctaa aattgacaac aataactatg acaaaaaaaa tagaagtata tgttgatgga
    40321 tcacaagaag aaagggattc cttttttgat tttttttgga aaaatagtag agaatatgta
    40381 aaagcgttga atctggtata taaacagcta atgtttgaag agttgataaa agatgcaatt
    40441 aaagaaatgg atcaaggtta tgctgagaga gaagaaagta ttcaaaatcg gattgaaaag
    40501 ttagcatata ctgatccaat agatcaaaaa aaacttgata aagcaaaagc tgaattatct
    40561 aaattgagaa atgaaaaaaa taaagaagcg agagaaatat taacgcaagc gatagggttg
    40621 aagagtcaaa cgagaacacg agatgtagca aaaaaattag actttgactt tggagatttt
    40681 gttgattccg caaatatgaa agctagtaaa gattttggca atgattttat cggaattgtg
    40741 accggacaaa gaacgcctag aatatataaa aatagaaaca aatatggatt actacctttt
    40801 agaggtcgag atattaaaat ccataaagat gataagtttt atatttattt acctaaaggc
    40861 tttaggttta aagtgaattt aggtagcaag ccaagaaaag caagagatgt tgcttcagtt
    40921 ttacaacaca ttatggatgg cgattacaaa ttaaatcaaa gtaatcttat ttttgatgga
    40981 agaaaattat tttttaatct aacaatttct tttgaaaaaa gctataatga aatggaattc
    41041 aagaaaggta atgaattgat cgtaaacttt gcagatttgt gtagcggtga atgtttaatt
    41101 aatgataaat ctgtaatgtc ttttggtgat agccaatata taagaaactt caaaagtaaa
    41161 attttagcaa tgaaatcaaa agaacaaagc cgaggagtct tttctaaggg cggtcatggt
    41221 cgaaaaagaa aattagatca agatcgatgg gaagcaataa agaaaagaga aagtaatttt
    41281 gttaaaactt ataataatca atgttctgca aaaatcgtta aaactgctat tcgcaataaa
    41341 gctcaaatta ttcgtatcat tgaaccagat aaggcttatg gcgaatgggc ttactatcaa
    41401 ttgaaagaac aactagtaaa caaaggaaaa agatatggga tagaagtcag aagttagtaa
    41461 attaaacaat cgttgatttg gcaacgaaat agtgagggaa aatccactca ctgaagggta
    41521 aactccgtca agttgtgtga ccagacggaa ggacgaatgt tgttgaggtt ttagaaccat
    41581 ataaaacagc atgtttctca aatttttagg ataagggaaa ttgctagcag tttgttttag
    41641 aaccatataa aacagcatgt ttctcaaatg agtactttaa attaattgat ggcgttcctg
    41701 ctttagaacc atataaaaca acatggattt aaaacaagaa gtaagtcagt tctcctttta
    41761 ctttagtaag gaaaaataaa gtattctcaa taaaacttaa aataagcaaa cctttgtttt
    41821 aatagctaat cgaagtaaaa cccaaagcca tatgaacccc tgaatcagcg aaagtttatg
    41881 atgatttgga ttactaatag tttaggaatt agatggtaaa tctaaattaa acaatcgttg
    41941 atttggcaac gaaatagtga gggaaaatcc actcactgaa gggtaaactc cgtcaagtta
    42001 tgtgaccaga cggaaggacg aatgttgttg aggttttaga accatataaa acagcatagt
    42061 tctcaaattg tttaaaatga ttgtcaagtt aaaaaaatct gggatcatat aaaatagtat
    42121 agttctcaaa tatgattaga aaccctatta aagagcaata ttaagccaac ttacttaaat
    42181 cgtttaatta agaacaataa tctcttttag tcagactttt agtctgactt ttttgtattt
    42241 ccaaaattta ttctttacaa aaacgaacat acgtttgtat aattgcttgt gaatggggga
    42301 ataaaaatgt ttgattacag tagagaaccg gtgaatgact attttttaat cgacatgaag
    42361 tctttctatg ctagcgtgga atgtattgaa cgaaatttag acccaatgac tacaccgtta
    42421 attgtcatga gtagatcgga caacactggt tcaggtctga ctctagcttc ttcacctact
    42481 gcaaagaaaa aatatcatat tactaatgtt agtagagcta ctgatttacc ttatccatta
    42541 ccaaaagaac ttcatattgt tccaccacga atgaacttat atataaaaaa aaatatggaa
    42601 gttaatcaga tttttagaaa gtatgtcgca gatgaagatt tattgattta ttcgattgat
    42661 gaatcaattt taaaagtgac aaaatcctta aatttattta ctagttcagg aacaagaagc
    42721 gagagaagaa gagaattagc taaaataatc aaagatgaga ttcagaaaga aacaggtcta
    42781 atagcaacag tcggaatagg agataaccca ttattagcta aacttgcact ggacaatgaa
    42841 gcgaagagta gtaaagaatt tatagctgag tggacttatg agactgtacc tgaaaaaata
    42901 tggaaaataa acgagatgac tgacttttgg ggcattggat cacgcatgaa aaaaagattg
    42961 aatcatatgg gaattatgag tatagaagat ttagcaaatt ggaatcccta cacaattaaa
    43021 agtcagttag gtgtaatcgg actccagtta tatttccata ccaatggaat tgatcgtacg
    43081 gatattgcta ttccaccaga accaaccaaa gaaaagtctt atgggaattc acaagttcta
    43141 ccaaaagatt atacgaggag agaagaagta gaactagtag tcaaggagat ggcagagcaa
    43201 gtagccattc gaattagaca acacaattgc aaaactggtt gtgtacgctt agcaattggt
    43261 acgtcaattt tggaagaaaa atcaggtttc tcgcaccaga tgaaaatacc aattacagat
    43321 aatacgaaag aattacaaaa ttattgtctt tttttattca ataagtttta tgaggggcag
    43381 gaagtacgac atataggagt aacttatagc agattagtat acacagattc cctacaatta
    43441 gatttattta gtgatccaag aaaaaagatt gctgaagaaa atttggatag gattattgat
    43501 aagattagac aaaaatatgg atttacagct attatacatg cttcatctat gttagaaggt
    43561 gcaagaagta ttacgagaag cactttaata ggaggacacg caggaggatt aggaggtttg
    43621 cataatgatt gaatataacg atagaggacg tttaaaatgg tcgggatttt atttgtctga
    43681 tcatactgaa agaatcaatg cagacaatgt acaacgtgct aatcataatt tggcaaaaga
    43741 acaaatgacg actgaagaga ttgcgaaaat actgagaact gctgtcataa aaaatagacc
    43801 cgtctgcatt caaaaagagg aacgaaacgc tgaaggttac tatccagatg atgtagtagg
    43861 aaaaattatt ggatatgacg agcttggtgt atttgtggaa gaagaaaaag ttcactatga
    43921 tgaaattagg aatgtttctt tctcggaatt attaaaatgg agtcagatat gaacattatt
    43981 aaaaaatacg aattcggtta tattacgtat gaacagctaa tagaggaatt atggggatat
    44041 ggtcaacaat taattaatga agtggggatt gattgctttt gtttctatat tgaatccgga
    44101 gcaggatacc ataagaacag atactatata tttccatatc caccaaaata gtctcttaga
    44161 tatttttaaa ttttctccaa atactttcaa ttattgtgaa atatttccct ttaattaatc
    44221 aaatttttta taaaagtaat atataaaata aattgcttga agtattatat ttagatatca
    44281 taatttatgg aagaaaaatt aattaaaaag gatgagatta taatggggtt actggttccg
    44341 agagctaata cttatactat acctttaacg aaacgccaat taattgctaa aagatatcaa
    44401 aggattacta gagccatcaa tagagagttt tggaattctg aaagtgatac tgctcacagt
    44461 ttatacgtag gttcttatgg gagaggaacg gcaattagta ctagtgatat agatataata
    44521 gttgaattac cgatggcaga atttgacaga ttcaaaaatt atttatcaaa tggcccgtct
    44581 aagttattac aagttataaa aaacgcattt caggaaatac taccaaatag tgatattaga
    44641 gctgatggac aagttgttaa aataaatttc catgatggaa tcaaatttga aatagttcca
    44701 gcttttaatg aaaaagatta ttggggtgag tcaaaagggt ttatttatcc agattcaaac
    44761 atgggaggga actggaaagc tacaaatccc aaaaaagagc aagaagccat gaaattaaag
    44821 aatacaaaaa gtaataattt attatatgct acgtgtaaac attttcgaca tgtacgagat
    44881 acagaattta cgagttatca tctttcagga atagtaattg acagtttcgt atatgaggct
    44941 atgggaaatt ggaaattcgt tgaaaataac agtgggggtc aaaacattag ttctgtatct
    45001 tatgagacag ctttattaga atactataac tcacataaag ttatgggcgg tttaaattta
    45061 tactctcctg gaagcaatca atttgttaat tctgatagta gtatcatatg tttagaaaaa
    45121 gtattaaaaa aaatagcttt ataaagtttt atggaggaac aacatgggag acgaaaaaaa
    45181 gcgcttggaa gttcaattac gtgaagcata tggacgagta acgtatactt acaccactca
    45241 tttaaagcaa gccgataata ttatttctga caataaaatt ttaaggtgtc ttcaaattgg
    45301 tttgtcagcc cttactactg gaggggtact tagtaccatt attactgata atagtgagtt
    45361 aacctttgtt gctggattat gttcaacaat ttctcttgga ttaaacttat actttaagaa
    45421 ttttgatctt gctgaagaag ctaaaaatca tcaaattgtt gccgataaat tatggttgat
    45481 cagagaagaa tacgtaagct tactaacaga tttaaatcgt ttaagtgttg aagatattgt
    45541 gaaaaaaaga gatcaattaa tgaacgaaac tcatgaagca tataaaaatg cccctaaaac
    45601 aaatagtaaa agctatgaat cagctcagaa agcattaaaa tctgaagaag agcaattttt
    45661 tacagaagag gaattggata agatgttacc agagcatctt agaaaaaaga gttctaaata
    45721 ttgaactctt tttttatgct taaaattctc ttgtaatttt tctattcatc tatatttaag
    45781 aagaaatatg atgatagaaa catctcctaa agccaccgca agccgttcta agcatagctt
    45841 agcccgacat tgctagatat gctcatctca ccatgaacgt ttcctaaagc caccgcaagc
    45901 cgtcctagcc attgcctagt ccgacatcgc tagattagtg catctcgcca taaaagtttt
    45961 ctaaagccac cgcaagccgt cctagccatt gcctagtccg acatcgctag attagtgcat
    46021 ctcgccataa aagttttcta aagccaccgc aagccgtcct agccattgcc tagtccgaca
    46081 tcgctagatt agtgcatctc gccataaaag ttttctaaag ccaccgcaag ccgttctaag
    46141 catagcttag cccgacattg ctagatatgc tcatctcacc atgaacgttt cctaaagcca
    46201 ccgcaaaccg tcctagccat cgcctagtcc gattttgctt gatcggttcc atttctgttt
    46261 atttagtggg tcaacaccgt aatcttaaat agccatcgcc tatttaagat tactaggtct
    46321 gctttgaagg taaaaagtct ttcattcttc aagactttta ggctttcaag ctacgcctga
    46381 aagcattgaa attcatcgct ctttatttgg ttttgccatt tataattcct tacgcccatt
    46441 atctttttcg cctgtcatac cttgtcagaa gtgtttagag cttatctcat ctttggatta
    46501 atacaagtgg cgtaaatttt tttctaaacg caagcgttac gaaaataatt tacttaaaca
    46561 cttgtattaa tccggcagat aagaacgcat tctaatcact cccgacaagg caagacaggc
    46621 gaaaaagata aataaatgaa cgaaaggaag aaacataaaa tgcaaaacca aatagcgatg
    46681 aagaaaaaac cacctccctc taaaacaatc caaacaaaaa agaattttga aaaaccaaaa
    46741 atcaaaaaca gaaagaagcg ttcaacatga gagatagaat tttagaagtt aatcaagaaa
    46801 tggtaaacaa gttaacaaat atcagtggga actatgaaaa gtacgatggt actttacttg
    46861 ataactatat ttttcacgat acacaaaata tcagaattgg cagaagtaaa ccgagagcgt
    46921 tcattctcat caaagagaaa tatttgaatg aatggaatag cacctatgaa atggttatga
    46981 ctgataactt tgaaaaggta ttggatttca gaaatgcttt gttgggttct gatatgggaa
    47041 atagcagtct tgaatctatt gaagttgaaa acaagaccga gaatgaaggt gaaggattga
    47101 ttaagaatgt cttgaaaatc gaacaaaaat atatcagtga agatagaagt ttttatagag
    47161 tcacaagctc ggttggtcta gcaaactttg ctactaactt aattggaaac aatgctagtg
    47221 aatctttgct agtgatgtgt ctgaatacaa agaatgaggt cattgcttat agcgaagttt
    47281 tcaaaggtgg aattaatcaa tcagtagcga taccaagaga gatttttcaa ctagctttgc
    47341 taaacaattc agcaaaaatc gcagtatcac ataatcatcc gagcggatat gaatttccaa
    47401 gtgaaaatga caaaagtttt actacgaatt tgaaaaacgc aggaaaaaca attggtattg
    47461 aattgttaga ccatatcatc gtaacaagta aaaacacaag ctattactca tttcaagaaa
    47521 atggttcttt ataaaaatta gagaaaagag gaaaacaaga tgggcgaaag aacacaagcg
    47581 ttaattacag tcaaatatgg taacagcaaa acgaaagcaa gcgtgtcgat tcattatcag
    47641 tgggggtatg gtcgatatat gctgatggac gtattgaatc aaggaattta tttaatcaat
    47701 aaagcatacg acttacgaga taaatcaaga gaagaattag caaaaggaat ctttgataga
    47761 agtacaggag ttatcaattt tgttacctat gaatctggag tgagtgctta tgatgaaaca
    47821 gggtttggtg ggcgctatga accttatcaa gaaacgattg aagatgtgat gaagttttca
    47881 gataacaatg atggctatgc tcatttagag atggtgttcg atgaaaatgg atttagtcta
    47941 gatgataaaa ccagattgcg attgtttgat tttgagggtc aacagatagg actaaacaag
    48001 ttttgtgaaa gcggaaaaga gtttgctacg aaagatttta ttaagggata cagattattg
    48061 ctagaaaatt atggaataaa cctagaagaa gagagcgtga aataagtgtt tgaaaaaaga
    48121 aaagaccagt tccctaattt agaagcgaaa agtcaaaaag tgattgatgg tgaaatgatt
    48181 gaattattcc aaaaaagtta tggaaccata gaaactaccg caagttgcaa atactacttt
    48241 caaggaaaga gaaacacgtt taaaggcttt gccgattctg atgaagaatt ggcaaagaaa
    48301 atcattgatt ggcttgtcag cagtgaacac gtagcaaggg aagataccgt tagaacaacg
    48361 attaatgggg aagtcctaac aggtactaga tgtgtttgtt gtaatcatga atttgtagaa
    48421 gatgaaggtt gctaccgaat caatgaatat ggtgatttta tttgccagag ttgccacgag
    48481 atagaatttc caaccgaaag aagttggttt gaatacatgc tacaagatta tgagatggaa
    48541 aaagaaaatg gtgaagtagt tttttgtacc aaagaggaat tgagtaagag aagcgatgat
    48601 gaaattgaag attggtgtgt gtggttagta ggggcagatg attgcgttgc atattacaca
    48661 acagcagaat aggagtgtga atcagcatgg aaggaatgga ttttctagat catgaagatt
    48721 tggttgattt tggttataca tggaaaggaa tggtaggtat tagcagaagt cttgctaatg
    48781 ccttttacga aagaaattat gcagtatatg ttctttatga tgacgataca gaaagccttg
    48841 ttgacgagga atataaattg gatttagaga atgttttata tggaatagaa aaggaagatt
    48901 tagcaaaata tattttttca tggttgggtc aataagtgaa aggaagatag aaacatgaca
    48961 aaatttaaaa gtaagggtat gcaatggtgt tcttattatt atgttggaaa tgatgaagat
    49021 ttattgagaa aaacccaacg aaaaggttat ccagataaga tattgaaaca aataggttat
    49081 tacatgccag aagagaggat agaaaaagaa ttttgtgagg ttctttttga tagtgaacag
    49141 ctattagttt tgttaaccca aaataaattg atttgccaat ttgaaaataa ttaagatgag
    49201 gtggtgaacc atgaatgaag ataagatggt attaagtgaa tatgctagat tgagaactat
    49261 taattcttta gcatctcatt taagttgttc tttcctaaca aaggtgctaa aattaattta
    49321 caaatgtgaa gattttgtac aagagaagca caaagacaag cctactgcga ataggcttgt
    49381 ctttttttca ttcattacga ttccgtatgt gtgggttagc gacaatttgt tcaattaccg
    49441 tatgatatag catcttaatt tgattagatt acttgcaatg tagtttatta agagtataat
    49501 ataatcataa atgtggacaa tttgataaat aatgagtgtt ttatactcaa aaggagtgga
    49561 tgaaatgaag gtcaaaaatc caactgaaaa aagcagaatc caagtcggaa tagacaagaa
    49621 tttaaaagag aacgcagaaa tgatattgga agagctaggt ttaaatccta caacagcaat
    49681 aacaattctt tacaaacaag tagtcgctag aggtgagttt ccagtagaga taaagctaag
    49741 tgaagaggag aagcaaggaa tcagattgca acagctaact aaggacatgc cagtagatgt
    49801 tctagataca gatgaaaagt tagaagagtg gttcgatgaa gcctaatgag atagtaacgg
    49861 tatatgttgc atttacagat aaaaatggtg gtaaaagaag acctattttg gtggttagtg
    49921 ataaagaaga tagagtagaa ttctttggaa tcacaagtca atatgagaaa aaatcagacc
    49981 aaataaagag ggtgtatttt cctattgcag aatgggaaaa agcaggactt aaaaagcaat
    50041 catggattga cgtagggtct ttaaaggcta ttcccaaaag ccgagagaac atatcattca
    50101 aaaaggttgg tatgttatca gctagtgata cgaaaaagct aaataggttt atcgagaaat
    50161 tacaaagaaa agtctaacaa ggcttttctt ttttgtttat atgtatatta agatatacgt
    50221 ttatataaac gtatttatgt atatgaaaat atacgtaaat atatacgtgg ttataaacat
    50281 taataaaacg ttaagaattg ttaaataatg atatttagta atatacgaat tataatatat
    50341 attttatata aaatgtatgt aaataaataa aatgtctgac ggatattgaa tagcaataaa
    50401 taacaataat tcagacggat acggtgagtg aagtagcttg ctacgaacga acaggcagaa
    50461 tgaaacggca gtttcattag agcaagtcgc ttgcgacgta gcgttaccgc tgatgtaact
    50521 ggcaagttac atagagagag tttgcttgca aacgaacgtt acctatttga atagaaataa
    50581 aaaataacag attagtgaat tttgaatagg agccacaact caaccaaccg cttgcggtgg
    50641 gtgagtccca cggaggaaaa gacga
//
LOCUS       DAPBBR010000019        49856 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPBBR010000019 DAPBBR010000000
VERSION     DAPBBR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.019"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            387..3194
                     /locus_tag="RD488_001121"
     CDS             387..3194
                     /locus_tag="RD488_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7657210.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3385..3876
                     /locus_tag="RD488_001122"
     CDS             3385..3876
                     /locus_tag="RD488_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7657211.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3979..4968
                     /gene="manX"
                     /locus_tag="RD488_001123"
     CDS             3979..4968
                     /gene="manX"
                     /locus_tag="RD488_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDT7657212.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            5001..5804
                     /locus_tag="RD488_001124"
     CDS             5001..5804
                     /locus_tag="RD488_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HDT7657213.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5825..6739
                     /locus_tag="RD488_001125"
     CDS             5825..6739
                     /locus_tag="RD488_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDT7657214.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6822..7196
                     /locus_tag="RD488_001126"
     CDS             6822..7196
                     /locus_tag="RD488_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HDT7657215.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7335..7580
                     /locus_tag="RD488_001127"
     CDS             7335..7580
                     /locus_tag="RD488_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7657216.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7752..8816
                     /locus_tag="RD488_001128"
     CDS             7752..8816
                     /locus_tag="RD488_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7657217.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9062..9487
                     /locus_tag="RD488_001129"
     CDS             9062..9487
                     /locus_tag="RD488_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7657218.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9480..9929
                     /gene="nusB"
                     /locus_tag="RD488_001130"
     CDS             9480..9929
                     /gene="nusB"
                     /locus_tag="RD488_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDT7657219.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10026..10880
                     /locus_tag="RD488_001131"
     CDS             10026..10880
                     /locus_tag="RD488_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HDT7657220.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10881..12218
                     /locus_tag="RD488_001132"
     CDS             10881..12218
                     /locus_tag="RD488_001132"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDT7657221.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12223..12447
                     /locus_tag="RD488_001133"
     CDS             12223..12447
                     /locus_tag="RD488_001133"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDT7657222.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12449..13339
                     /locus_tag="RD488_001134"
     CDS             12449..13339
                     /locus_tag="RD488_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7657223.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13348..14166
                     /locus_tag="RD488_001135"
     CDS             13348..14166
                     /locus_tag="RD488_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDT7657224.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14273..14722
                     /locus_tag="RD488_001136"
     CDS             14273..14722
                     /locus_tag="RD488_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7657225.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14740..16422
                     /gene="recN"
                     /locus_tag="RD488_001137"
     CDS             14740..16422
                     /gene="recN"
                     /locus_tag="RD488_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDT7657226.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16477..16593)
                     /locus_tag="RD488_001138"
     CDS             complement(16477..16593)
                     /locus_tag="RD488_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HDT7657227.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16666..17622)
                     /locus_tag="RD488_001139"
     CDS             complement(16666..17622)
                     /locus_tag="RD488_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7657228.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17793..18161
                     /locus_tag="RD488_001140"
     CDS             17793..18161
                     /locus_tag="RD488_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HDT7657229.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18331..18762
                     /gene="mraZ"
                     /locus_tag="RD488_001141"
     CDS             18331..18762
                     /gene="mraZ"
                     /locus_tag="RD488_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDT7657230.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18783..19742
                     /gene="rsmH"
                     /locus_tag="RD488_001142"
     CDS             18783..19742
                     /gene="rsmH"
                     /locus_tag="RD488_001142"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDT7657231.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19747..20148
                     /gene="ftsL"
                     /locus_tag="RD488_001143"
     CDS             19747..20148
                     /gene="ftsL"
                     /locus_tag="RD488_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDT7657232.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20149..22341
                     /locus_tag="RD488_001144"
     CDS             20149..22341
                     /locus_tag="RD488_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7657233.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22367..23329
                     /locus_tag="RD488_001145"
     CDS             22367..23329
                     /locus_tag="RD488_001145"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDT7657234.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23343..24704
                     /locus_tag="RD488_001146"
     CDS             23343..24704
                     /locus_tag="RD488_001146"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDT7657235.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24730..25818
                     /gene="murG"
                     /locus_tag="RD488_001147"
     CDS             24730..25818
                     /gene="murG"
                     /locus_tag="RD488_001147"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDT7657236.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25833..27053
                     /locus_tag="RD488_001148"
     CDS             25833..27053
                     /locus_tag="RD488_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDT7657237.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27209..28534
                     /gene="ftsA"
                     /locus_tag="RD488_001149"
     CDS             27209..28534
                     /gene="ftsA"
                     /locus_tag="RD488_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDT7657238.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28557..29798
                     /gene="ftsZ"
                     /locus_tag="RD488_001150"
     CDS             28557..29798
                     /gene="ftsZ"
                     /locus_tag="RD488_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDT7657239.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29815..30492
                     /locus_tag="RD488_001151"
     CDS             29815..30492
                     /locus_tag="RD488_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDT7657240.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30506..31105
                     /locus_tag="RD488_001152"
     CDS             30506..31105
                     /locus_tag="RD488_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDT7657241.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31120..31407
                     /locus_tag="RD488_001153"
     CDS             31120..31407
                     /locus_tag="RD488_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDT7657242.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31456..32238
                     /locus_tag="RD488_001154"
     CDS             31456..32238
                     /locus_tag="RD488_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDT7657243.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32259..32966
                     /locus_tag="RD488_001155"
     CDS             32259..32966
                     /locus_tag="RD488_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDT7657244.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33228..36026
                     /gene="ileS"
                     /locus_tag="RD488_001156"
     CDS             33228..36026
                     /gene="ileS"
                     /locus_tag="RD488_001156"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDT7657245.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36075..37601)
                     /locus_tag="RD488_001157"
     CDS             complement(36075..37601)
                     /locus_tag="RD488_001157"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDT7657246.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37616..38263)
                     /locus_tag="RD488_001158"
     CDS             complement(37616..38263)
                     /locus_tag="RD488_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDT7657247.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38447..38776)
                     /locus_tag="RD488_001159"
     CDS             complement(38447..38776)
                     /locus_tag="RD488_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HDT7657248.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38953..39681
                     /gene="sfsA"
                     /locus_tag="RD488_001160"
     CDS             38953..39681
                     /gene="sfsA"
                     /locus_tag="RD488_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDT7657249.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39697..40710
                     /locus_tag="RD488_001161"
     CDS             39697..40710
                     /locus_tag="RD488_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7657250.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40710..41987
                     /locus_tag="RD488_001162"
     CDS             40710..41987
                     /locus_tag="RD488_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7657251.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42050..44752
                     /locus_tag="RD488_001163"
     CDS             42050..44752
                     /locus_tag="RD488_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7657252.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44904..45221
                     /locus_tag="RD488_001164"
     CDS             44904..45221
                     /locus_tag="RD488_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7657253.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45251..45571
                     /locus_tag="RD488_001165"
     CDS             45251..45571
                     /locus_tag="RD488_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7657254.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45679..47139
                     /locus_tag="RD488_001166"
     CDS             45679..47139
                     /locus_tag="RD488_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7657255.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47207..47428
                     /locus_tag="RD488_001167"
     CDS             47207..47428
                     /locus_tag="RD488_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657256.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47459..47641
                     /locus_tag="RD488_001168"
     CDS             47459..47641
                     /locus_tag="RD488_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HDT7657257.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47641..48054
                     /locus_tag="RD488_001169"
     CDS             47641..48054
                     /locus_tag="RD488_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDT7657258.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48177..49358
                     /locus_tag="RD488_001170"
     CDS             48177..49358
                     /locus_tag="RD488_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7657259.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49429..49593)
                     /locus_tag="RD488_001171"
     CDS             complement(49429..49593)
                     /locus_tag="RD488_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657260.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49747..49820
                     /locus_tag="RD488_001172"
     tRNA            49747..49820
                     /locus_tag="RD488_001172"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49781..49783,aa:Arg,seq:cct)
BASE COUNT        16590 a         8433 c        10773 g        14060 t
ORIGIN      
        1 ttttttgttt ataaaaataa aagttgtagt ggaggctacg aagtttactt tgtcttttta
       61 cacttaatat ttttttgcca atttggaatc aggatgtttt gataactatc gttttcaatt
      121 gatggaagct atattgtttg ctatcagtga aataattata tggtaaacag tgttcttttt
      181 cttgtttcca ttataaaaat cgtatcggga tttttcgttc ttttaaattg aacatttcta
      241 tctatccgcg tgttatcaac aaaacaaaat caggtaaata gttgacgaaa cagaaataaa
      301 tacatagtat tatgttttga agcctaagta caatagtcta tagaaaagga gcgataccat
      361 tggcaaaacg cattgaccga atttatatgt atgtcaaaga aaaaaccgct catttaacaa
      421 aggcagaata tgatcaagga gtaacaacac aggaaattgc tgaagtgtta gggattcagc
      481 gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga aggaaaactg ataaagacag
      541 acggacgacc agtacgttac atatatcaaa cactcgttac gcacgtaaag ccagttacaa
      601 aacatgtagt cagttacaaa gaaacgccgg tctctgaaga aaaaaataca ctccaaatag
      661 atactaagga tatctttgca aaaatcattg gagctaacgg cagcatgaaa aattcagtgg
      721 aacaggcaaa agctgcgatt ttgtatccgc caagaggatt aaattgtttg attacaggac
      781 ctaccggatc aggaaagact tattttgcac acgcgatgta tcattttgca aaagcgcatc
      841 atgtaataga tgaggaaacg gaactgattg ttttcaattg tgctgattat gccaataacc
      901 ctgagctttt gatgagtcat ttatttgggt acgcaaaagg tgcttttaca ggcgcagatg
      961 aagaaaaaat ggggattatc gatcaagcgg atggcggtat gctgtttttg gatgagattc
     1021 accggttgcc gcctgaaggt caagaaatga tcttttactt tatggatcat ggaacttaca
     1081 gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt acggatcgta ggtgcgacca
     1141 cagaagaccc aggttcttct ctattagaaa cttttgttcg gcgtatccca atcaatatca
     1201 aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt cgatttagta aaaatcatga
     1261 ttgcccacga agcaaaccgc acgcagcgaa agatttcttt gacagaagat gtagcaaaag
     1321 cattgatcgg cagtgtgacc tatggaaata taggacaatt gaagtcaaat atccagttag
     1381 tatgtgcacg aggatttcta aatcatatgc aatcacccga aatctcgatc acaatcgatg
     1441 atttgacaga agggattcgt agcggattga ttcaattagc aagcaaccgc agtgcaatgg
     1501 cagagctttc taaaatattg gagccaaaga taactgtagc accaaatgat acgatcatga
     1561 aaatccaatc ggactcctat gagttacctt ataatctata tgatatcatc ggagataaag
     1621 cagctttact gaagtcggat ggtttggatc aagaagcaat caatcatttc atttctacag
     1681 atatcaacat ccatctgaag tctttctata aagaccatgg tttttctttt aatgcagaca
     1741 gcaaattagc agaatttgta gatccgaaaa tcatagaagt gaccaatcag atttatgtaa
     1801 tggtcaaaag atctttacca tatgagtttc agcaaaactt tatttatgct atgagcttgc
     1861 atatcagttc ttttttgaaa aaaatcaact taggagaaga acggcatacg aatgataaca
     1921 tccgtgagat ggcttttgat tttccagatg aatatgctgt tgcgaaagaa gtgcgtagtt
     1981 atatcgaaac gtattttcaa gtggagattc cagaaagtga agactattac ttgaccgttc
     2041 tactcgtctc gttacgggca aatcaagcaa gcggcagaat cggtgtagtc gttgcagctc
     2101 acggaaacag cacagcaagc agtatggtcc aagttgtcca acagttgtta gatgcagaga
     2161 acgtacgagc agtagacatg cctttggata tggatccgaa aacagcattg gaccgaattg
     2221 aacgcaatgt acaagaagta gatgaaggaa gcggggtcat actcttagta gatatggggt
     2281 cccttgcgtc gtttaattcg caaattcaaa gagacactgg aattccagta cgtactgttg
     2341 atatggtaac aacttctcta gttttggaaa ctgtacgaaa ggtctcagta ttagggacag
     2401 atctagatat gttgcatgaa tcattgaaaa attttcgagg ttacgcagaa atatcttctg
     2461 tagaatctgt tcaggaagca aaacctattc ataagaaaaa agctgttttg gctatctgcg
     2521 catctggcga aggtacagca caaagaatca aagaattgat cgaacgagcg gtaaacaagc
     2581 gtcaagaaac agaattagaa gttctagctt tgtcgattgt ggaagtgaaa gaagaactgc
     2641 cagttatcca aaaagaatat cagatcatag ctactactgg gattactgat ttgaatatcc
     2701 aagccccatt tattccttta gaacgtttta ttgatcaaaa tatcgaagtc attttggatc
     2761 agttgctgat ggaatcagaa ttggaggaaa ctgaattcat ctccctagat gaagagtcag
     2821 ctaaaaatac gtgtgttgag tttatctctg ataacttcat ctttattaat ggtagtaagt
     2881 taatcgatcc aatgtggcaa ttttctacac aaatctctca gacgacggga atcggcgatg
     2941 aagaatatgg attcaaaatc aacctagtga tgcacacagc aggaatgatc gaacgtatta
     3001 ttcggaatga accattgact gtggaagaaa acgaattgac aaatacaacg aatgatcctc
     3061 tttatagcca attggcagcc tcagttgttc tgttggaaga tcagataaaa gtaaaagtgc
     3121 cgatagaaga aatgtattat ctgctacgtc tagtccataa tcagttagat aaaaaagaat
     3181 acactgtgcc atgaatacac aaaaacgata cacttttata gtgtatcgtt tttgtgtatt
     3241 ggttaagaat cctttaaatt caattagtgt atcgtaaaaa agttggcacg ctttttgctt
     3301 atagtagtgt gtgctaggag gtggttgttc acacagaaat gataggggtt tctgtgaagt
     3361 agtgaggaag aaggagtttt gcagatggat attcgattgg cacgtataga tgatcgttta
     3421 atccacgggc aagtcgcaac agtttggtcg aagcaaacag gtgttgaacg tatcattgtg
     3481 atcagcgatg tagtcgctca agataaattg agaaagtttc tactaaaaga agctgcaccg
     3541 ccggggatca cagcaaatgt aataaccgtg cagaaaatga ttcaaatcta tcatagtgga
     3601 ttattatcac gagcaaaagt gatgctttta ttcaccaatc cccaagatgt tgaagcggtt
     3661 gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg gtatgagttt tactgaaggc
     3721 aaatcaatga ttaccaattt tgtttcagta aatcaacaag atattgattc ctttcgttac
     3781 ttgaacagtc aagaagtgga gttagagatt cgaaaagtac ctgctgacag gaaaatcctt
     3841 ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag aatggttgtt ggaaaaggtc
     3901 aaataattct gttgtaatgg ttagcaatta ttaatatttt tgaatttgtt acaacaaaag
     3961 taaataggag gtataaatat ggtagggatt atcctagcaa gtcatggaca atttgctgaa
     4021 ggaatcttac aatccggttc aatgatcttt ggcgaacaag aaaacgtcaa agccgtgatt
     4081 ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat tggaagaagc ggttgcttct
     4141 tttgataatc aagacgaagt gttattctta gttgatttat ggggcggaac accgttcaat
     4201 caatcaaaca cattattcga agagcacaaa gataaatggg caatcgtcag cggtttgaat
     4261 ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa tggaatctgc tcatgaaatt
     4321 gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag taaaaccgga agaattagaa
     4381 ccggcagaag caccgaaagc agcagttgaa gacgcacaac ctaaaggagc acttccagaa
     4441 ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag cacgtgttga ctcacgtctg
     4501 ttacatggac aagttgcgac agcttggaca aaagcagtgc aaccaaaccg tattatcgtt
     4561 gtttcagatg cagtatcaaa ggatgatctg cgtaagagac taatcgaaca agctgctcct
     4621 ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga tcgaagtagc aaaagaccct
     4681 cgttttggaa ataccaaagc attgctttta tttgaaaatc ctgaagacgt attgacagct
     4741 gttgaaggtg gcgtagacat caaagaatta aatgttgggt caatggcgca ttcggtcggt
     4801 aaagtcgttg taagtaaagt attgtctatg ggacaagaag acgttgaagc gtttgagaag
     4861 cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac ctaatgattc acgcgataac
     4921 atggatgata ttttgaaaaa agcaaaagct gaattagcaa aagcgtaata aataatatta
     4981 aaatttatag gaggcttatc atgtctatta tttcaataat tttagtcgta ttagttgcct
     5041 ttctagctgg tatggaaggt attcttgatg aatttcaatt tcatcaacca ctagtggcat
     5101 gtacattgat cggtttagtt accggtaacc tcgaagctgg tatcgtactt ggcggtacgc
     5161 ttcagatgat cgctttaggt tgggcaaata tcggtgccgc tgtagcacca gatgctgcat
     5221 tagcatcagt agcatcagca attattttag ttttaggtgg acaaggtgtt aaaggtgttc
     5281 cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg gttgttctta acaatgatcg
     5341 tacgtacaat cgctgttcca atcgttcatt tgatggatgc ggctgctgaa gaaggaaaca
     5401 tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt acaaggggtt cgtatcgcgg
     5461 tcccagcagc agcgttgcta tttatcccag cacaaactgt gcaatcattc cttgaatcaa
     5521 tgccagcatg gttaacagat ggtatggcta tcggtggggg aatggtcgta gctgtaggtt
     5581 acgctttggt aatcaacatg atggctacaa aagaagtatg gccattcttc gttattggtt
     5641 tcgttgtagc tgcaatttct caattaacat tgattgctct aggtgcttta ggtgttgcat
     5701 tagctcttat ttacttgaac ctttctaaaa tgggtggttc atcaaataat ggaggcggaa
     5761 gcaactctgg tgacccttta ggcgacattt tgaatgacta ttaatcttga aggaggaaaa
     5821 taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat cgtttagctg ttgcgtggcg
     5881 ctctaccttc attcaaggtt catggaacta cgaacgtatg caaaacggtg gctgggcatt
     5941 ttctatgatt ccagcaatca aaaaattata caaaacaaaa gaagaacgtt ctgcagcatt
     6001 aaaacgtcac ttggaattct ttaatacaca cccatacatt gcttctccaa ttttaggggt
     6061 tacattggct ctggaagaag aacgtgcgaa tggcgcgcct gttgatgatg tagcgattca
     6121 aggggttaaa gtaggtatga tgggtccttt agctggtgtt ggtgacccag tgttctggtt
     6181 tacagtacgt ccaatgctag gtgcactagg tgcttcatta gctatgggag gaaatatcct
     6241 tggaccaatc atcttcttct taggttggaa cattattcgt tgggcattca tgtggtatac
     6301 acaagaattt ggctacaaag ctggttctaa aattactgat gacctttctg gcggattgtt
     6361 acaagacgta acaaaaggtg cttcaatttt agggatgttc gtattagctg cccttgtaca
     6421 aagatgggta tcaatcaaat tcttaccagt tgtatcaact gtaaaattag ataaaggtgc
     6481 ttacatcgaa tgggataaat tgccttcagg tggtgaagga atcaagagtg catttgaaca
     6541 agttaataat ggcttagccc tttctcctga aaaggtaaca acattacaag acaacttaga
     6601 ccaattgatt cctggtttag ctgcattagg attaacattg ttatgtatgt ggttgcttaa
     6661 gaaaaaggtt tctccaatcg ttatcatcct tggtttattc gtagtcggtg ttgttggaca
     6721 cgtcatcgga cttttataat ccataaaaat atagctcggg cgttgtcccg agcttttttt
     6781 atatagtata ctgttcataa acaaatatct ggagggagaa aatggttcaa tcaatcaata
     6841 caaaagtaga cttggtaatt gatgctactt cgtttacggg tctgacagat tacgggcaaa
     6901 tcatgatagg tgataatggt tttgagtttt accatgcgcg agatagacgc aaatatatcc
     6961 aaattccatg ggaagaagtg gattatgtac tagcatcagt catgctaaag ggaaaatgga
     7021 ttcctcgata tgccattcaa acgaaaaaaa atggtacata cacattttct tccaaagaac
     7081 ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga agatagaatg gtacaatcat
     7141 tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat gtttaaacgc aagtaaaaaa
     7201 taaagaaaac ttctaagagg aggttttctt tattttttta ctttgcagaa gaaaatatga
     7261 aatagcaaaa ccaattattt gtccccttta aatcccatat gctaaaattg attagcaaag
     7321 aaggaggtta tattatgagt tggttatgga cattgattgt tggagccgtg atcggagcaa
     7381 ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg tgtaacgaat atcattgctg
     7441 gactagtcgg ttcaagtatt ggacaagcga ttttcggcga atggggacca aaagctgcag
     7501 gtatggcact tattccatct attttaggcg cagtgatttt ggtagcagtt gtctcatttt
     7561 tctttggaaa acgatcataa gtttttacaa aatagtaaac taaaaggagt tgcagcgaga
     7621 ctgtgactcc tttttggctt tatttattta aaataaaaag aagttttccg gaaattttta
     7681 tttaactgtc gtgtacgaag aaaagtttgc tataatggaa aaaagcgtgc aaagaaagag
     7741 ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa aaaaatgcaa gaagaaaatt
     7801 tggattcatt tttggttacc agtccgtaca atcttcgtta cttaacgaac tttacaggta
     7861 cgacaggatt agctgttatt actttggaaa aagcattttt tattactgat tttcgttata
     7921 ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat taaaaatgtc ggacctattt
     7981 ttgatgaggt agcaaactta gtacgcaaag aagaactgca ctcattagct tttgaggaaa
     8041 caacagtctc atttttagaa tattcggttt tagaagaaat catcgatgcg gaattagtac
     8101 ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga tgaagaagaa atcgctatta
     8161 tcgaaaaagc atgtcatatt gcggatatgg catatgatca catcctgaaa atgatccaac
     8221 cgggcatgac tgagattgaa gtcgcaaatc aactagactt ttatatgcgt tctcttggcg
     8281 cttcaggtgt ttcttttgat acgatcgttg ctagcggatt gcgttcggct atgccgcatg
     8341 gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat cacattggac tttggttgct
     8401 attacgaagg gtacgtttcc gatatgacac gtacattcgc tattggtgat cctggggaaa
     8461 aattaaaaga aatttatcaa atagtcttag atgctcaatt agcagttatt gatgctgcaa
     8521 aaccaggaat gactggtgtc caattagatg cagttgctag agattatatt tcaaaacatg
     8581 gttacgggga agcatttgga cattctacag gacatgggat cggtttagag atccacgaag
     8641 gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc aggaaatgtg atcactgatg
     8701 aaccagggat ctacttacca ggaatcggtg gagtacgtat tgaggatgac ttgttgatca
     8761 cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga attgatcatc ttatagtttc
     8821 atcaatagaa gaagtaagcg taaaaatcag tgttcacaga ctttgttata gaaaatcact
     8881 cgatttaatg atacactata gaagaacttt taagctgtaa gagataataa agttgggtgt
     8941 tttctccaat tcatagcagt ttgcagctga tcggcggcag ttttcttacc acgtgatcac
     9001 tatgccgcat catagagaat tcggatgtat ctcgtgctta ggcaaaggga ggaataaata
     9061 aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa gatttaggag agatcgtgat
     9121 cgctcctgaa gtcatcgaag taattatcgg gattgcagct tctaaagtag aaggcgtata
     9181 cggaatgcgc ggaacttttg ccagcaatgt cactgaatta ttaggacgtg cagctcacgg
     9241 aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa gtagatcttt actgttatct
     9301 agaatatggt gtttcagttc ctaaagtagc aatggaaatg caggaacggg tcagccagca
     9361 agtccttttc atgacggata tcgatttatc tgaagtcaat atccatgtag tagctgttgt
     9421 tcctgaaaaa ttagaacaac caacaatcga agaacttttt gaagacgaag aggaagagaa
     9481 tgaataaaga attatcaaga cacgagattc gggaaatggc attgcaggct ttatttccat
     9541 tagacttcaa tgcagaccta acaaaagaag atgcgatttt caacgcaatc gaattagacc
     9601 accgcgacat gatcaacgaa gatgaatcag agtttgttcc tgtttatctt gatacgctag
     9661 ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt gattgaaaaa catttaaaaa
     9721 acaattggca catcaatcgg atctcaaaaa tggatttggt gatcttgcgt atcgcgattt
     9781 ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc tttaaatgaa gcaatcgagt
     9841 tggcaaaaac atttagtgat gaccgttcac gtaaattcgt caacggtgtt ttatccaatg
     9901 tattgaaaga attagaagct ggggcgtaag tcctagcttt tttctatgaa tcatcataaa
     9961 cctgttataa atcgggaaaa ttctatggta gaatgaaaac acaaaaaata tctgggagtg
    10021 gttagatggc agaattgatt aacggaaaag aattagctga aaaaatgcag gcagagattg
    10081 ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc cggattagtc gttttattgg
    10141 taggggaaaa tccagccagc caaatctatg taagaaataa agaacgtgta gcaaaagaaa
    10201 tcggaatcca ttcattggta gagcgttatc ctgagacgat ttctgaagac gaactacttg
    10261 cagaaattga aaaatacaat caagatccta gttttcatgg tatattggtc caattaccat
    10321 tgccaaagca tatagatgaa gaaaagatcc tgttagctat ccgccctgaa aaagacgtag
    10381 acggttttca tccgatgaat ttaggcagac tccttgcggg taaaccggac aagattcctt
    10441 gtactccata cggcatcatg aaaatgtttg aagcttattc tatcgatccg gcgggtaaac
    10501 gagcagtagt tatcggacga agcaatatcg tcggtaaacc gatggctcag ctactcttga
    10561 tggcagatgc aactgttact gttgctcatt ctaaaaccga aaatctggct gaactggcac
    10621 aagaagcaga tattttagtc gtagcaatag gacgtggaca ttttgtcaca aaagaattcg
    10681 taaaaccagg tgctgtagtg atagatgtag ggatgaatcg tgatgctaac ggtaagctga
    10741 tcggtgatgt gaaatttgat gaagtggagc ctattgcagg ctggatcact cctgtgccaa
    10801 agggtgtagg gccaatgact atcacgatgc tgatgtatca aaccgtaaaa tctgccgaag
    10861 cttttggagc aggtgaatag atggcacaag aatatttaac tgtcactaca ttaacgaagt
    10921 atttgaaaag aaaatttgat gccgatcctt atttagaacg cgtatattta acaggcgaaa
    10981 tatcgaattt ccgtttacgt gccaatgccc atcaatattt cagcttaaaa gatgaccatg
    11041 caaaaatatc tgctattatg ttcaaaggag cattccaaaa attacgattc cagccaaaag
    11101 aaggaatgaa agtccttgtc gttgggcgta tttcattata tgaagcggga ggttcttatc
    11161 aaatctatgt agagcacatg gagcctgatg gaataggtgc tttatatcaa gaattggaag
    11221 aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg gcctaaaaaa atgctgccac
    11281 gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg agcggttatc cgcgatatca
    11341 tcacgacggt gaaaagaaga tatccaattg tccaattggt tttgttccca acagttgtac
    11401 aaggaaacca agcagcggac aatgttgtca ggaatatcca gagagtagaa gagatgggca
    11461 atttcgatac aatgatcatc ggtcgtgggg gtggttcgat tgaggattta tggccgttta
    11521 atgaagagcg ggttgctcgg gcgatttatc aagctaatac gccggtgatt tcatctgtag
    11581 gacatgaaac agataccacg atcgctgatt tagtagcaga tgttcgggct gccactccaa
    11641 cagcagctgc agaattagct gttcctgttt tgtcagaaga gttgatgcgc attcaagaac
    11701 ggcaagctag attgcagcag gcgtttgtac gccagatcca gcgcaaacaa gaacggttcg
    11761 agcgtgctcg acgttcctat gtatttcggc agcctgaaag attgtatgaa ggtcagacca
    11821 tcaaattaga ccagttgaaa cagcgattat atcaagctac acagcaaatt tatcatgcga
    11881 aagaaaaaca aacgatcgca ttaagccacc aattggaaca agtggctccg ctttatcgag
    11941 ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg cttagaagag aaaatccaac
    12001 aatatatgaa acaacagcag cagcgttttg ctcaagctgt tcaatctctt gatttgttga
    12061 gtccattgaa aatcatggga agaggctaca gctatacgac gttaaatgat caagtagtaa
    12121 aaagtgtcac cgagattcat caaggggatt tgctgacgat ccattatcaa gatggaatcg
    12181 ttaaaggaca agtacaagag atagacaaag gagaataaaa atatggaaaa tccaactttt
    12241 gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt tagaacaagg agacgttcca
    12301 ttagaatcag ctctagattc gtttaaacga ggaatggaat taagcaaaca ttgccaagat
    12361 acattagcta aagcagaaga gaccttgacg aaaatgatga cagaatcaaa tgaagaagtt
    12421 gattttgacg gaaacgagga aagctgagat gagattaact gacttttcag ctattcatct
    12481 acctgctgta gaaaaagaaa tcttgtcttt tttagatgag catacaacgg atagaggact
    12541 ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa agaatacgtc ccttattact
    12601 tttaacggcc gttgcttcct ttgatgagcc tattgatgtt cccgtctatc aagtagcagc
    12661 tgctttagaa atggtgcata cgtattcctt gatccacgat gatttgcctg cgatggacaa
    12721 tgatgatctt cgtagaggaa aacctaccaa tcataaagta ttcggcgaag cattagctat
    12781 attggccgga gatggtttgc ttacaggagc attccagcta atcagtatgg cacacttagg
    12841 taattctcct aagcttctgc tgcttcagca attagctgtt tgtgcgggat cacaaggtat
    12901 ggttgctggg caagctgcag atatcgaggg cgaatcgaaa aagctttctt tagaagaatt
    12961 agcatttatt catgaaagaa agacagggca tttgattcgt tatgccttgc tggctggtgg
    13021 catattagcg aagcaacctg aagaaatctt attgctactt caacgattag ccgaacattt
    13081 aggtttagct tttcagataa gagatgatct actcgatgtg attggtacaa cgaaaacatt
    13141 agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat acttacccgc gtttattagg
    13201 cctagaaaag acacgtgagg cgttggagat tgagctgtta tccgccaaca agatcataga
    13261 caaattagaa gaggacgttt tttcttttga tggcgggctg atgcgccaga tgatcaagca
    13321 atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac gcgtagatgt attagcggtc
    13381 aaacaaggat tatttgaaac aagagaacaa gccaaacgtt cagtgatggc tggtttgatt
    13441 tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa aaattccagt gagtagtgaa
    13501 ttaagagtca aaggtaaaaa acttccttat gtttctcgag ggggattaaa attagaaaaa
    13561 gcactcaaag catttgatct atctgttgaa ggaaaaacat tgttagatat tggtgcatcc
    13621 actggcggat ttactgatgc agctttgcaa aatggcgcaa aaatgagtta tgctttagac
    13681 gttggctaca atcagctagc ttggaaaata agacaagatc ctagagtcgt cgtaatggaa
    13741 agagtgaatt ttcgttatgc aaaacccgaa gactttacct taggaattcc agaagttgct
    13801 gttatcgatg tttcttttat ttcactaaaa ctgatgctgc ctccattaca tgctatttta
    13861 aaagaagagg gagaagtgat tgctttaatc aaaccccaat tcgaagcagg cagagaagct
    13921 gtagggaaaa acggaattgt tcgtgaccct cagacccatc aaaaagtttt agaagacatt
    13981 ttgtcatttg cggcacaagg tggatatgat gtgctggaat taagttattc tccgatcacg
    14041 gggggagaag gaaatatcga gttcttggct cacttgagga aagtacccga aagcggaaca
    14101 atcaattcag ctattaatat ggcagaagtg gtttcaaatg cacacgaaca gtttgaccat
    14161 aaataaattg taactgtgaa aatcaagtga gaagtatgcg gattcttctt tattatacca
    14221 aggaaataag ctatcattga ttaagaagaa tatgctaagg agcgaagacg taatgagaaa
    14281 aaaagatcgg catcgtttga ttactcgatt gttgagtgag caagatatcc gaaagcagga
    14341 agaatttgtt gaaatcctga aaagcaaagg aatatctgtt actcaagcta cgatttccag
    14401 agatataaag gaactgaaac tgatcaaggt accggcttca gatggcggct accgttatag
    14461 cataccagct gaaacaaacg aagatgtaaa tactaaattg gaaaaactat taaaagacgc
    14521 tttcgtggca gttgaccaaa tggaaaaatt tgttattttg aaaacattgc cgggaaatgc
    14581 ttcggcagca gcaaatttga ttgataaacg ttacaagaaa gaattatttt cgattatcaa
    14641 tgatgacgat aatgttttga tgattacacg aactgaagac caggcagttt tattgaagaa
    14701 agacttcctg cattaccttt aagttgagga gcgaatgtga tgctacaaga aatcagtatt
    14761 actaactttg cgattattcc ggaattgcgg ctttcttttc acgaaggaat gaccgcgctg
    14821 accggagaga ctggtgcggg taaatccatt attatcgatg ctttaggtct gttagcagga
    14881 ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa aatgtgtgct tgaagggttg
    14941 tttgaactac caaaacaaga aggattctct gaactgatgg ttgaattagg gatcgaaaca
    15001 gatgaggaca atctgattgt tcgacgggat atgtccttaa ctggaaaaaa tgtttgtcga
    15061 gtgaatggtc atattatcac attagctaat ctgagaagaa tcggcagtta tttagtagat
    15121 atccaaggac aaaacgaaca tcaggaactg ctccagcctg aatcacatct tgctttattg
    15181 gatcgttttg gagatgtagc tttccaacag aagaaaaaga gttatcagca agaatatatc
    15241 tcttatcgtg agctggaaaa aagggtacga aaagtgcagc aaaatgaaaa atcctatgtt
    15301 cagagaatag atatgctcca tttccagcaa gaagaaatag ctgctgctga tttgcaagtc
    15361 ggagaagaag agaaattaaa agaagaaaga gaaaaactta gcaattatca aaaaattgct
    15421 gatggattag ctgcaggtta cggagcactg acgaataatg aacaaaacag tgtagatggt
    15481 gttggcttgg ccgtttcaga actgcaaggg atcgcccatc tagatgtgga gtatgaagca
    15541 atttatgaaa atatccaaag tgcttactat ttgctgcaag atgcaatcgg cgatatgagt
    15601 cgtcagattg atttattgga gttagatgag agtcgtttag aagaagttac gcaacgttta
    15661 gaattaatcc gacagttgaa acgtaaatac ggcgaatcca ttgagtcaat attggcttac
    15721 tatgacgaaa tcaccgaaga gctagcttct tctgattttt cagaaggtca attggacaaa
    15781 atgaaagagg aactagagca aaaagagctt ctacttcagc aacaagccgc agatcttcat
    15841 gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca ttctgcatga attgaaaagt
    15901 ctgtatatgg aaaacactga gtttgaggta cgtttcttaa aagaagaaaa tagacaattg
    15961 aatcatgatg gatttgacca aatcgaattt tacattacga ccaatccagg agagccactg
    16021 aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc ggatgttgct tgctttgaaa
    16081 actatttttt cttctgagca aggtgtgaca agtattattt ttgatgaagt ggatacaggt
    16141 gtgagcggaa gagttgcaca ggccatcgca gataaaattt ctcaaatatc gaaatactct
    16201 caagttttgt gcatcactca tctgcctcaa gttgctgcag tcgccgacta tcaatattat
    16261 attgtgaaag cagtgattga tggacgtacg caaacttctg tttcagagtt gaaaacaaaa
    16321 gaaagagaag aagaaattgc acgtatgctg gctggaagtg agattacaaa actcacactc
    16381 gaacatgcaa aagaactatt gaaactcgca aaaaggacct gagccacctc gcagtggttc
    16441 aggtcctttt cagcagctga tagctatatt ttatttttac atgacactca ttacagcagt
    16501 caatacaaca gatccaatcg ttaaaatcag cattgtccaa atgacaaatt ttgttacttt
    16561 agcaaaagta cttgtttgtt ttttttcacg cattgttttc aacctcgtca ttaattagtt
    16621 gattcaagtg tacaatcttt tttccatttc cacaagaggg cttttttata aaaacttccc
    16681 tttttttaaa taataggtag ttacgataca aataaataat gttaatagaa ctagccatat
    16741 aaaggcatca tccctttcag caataggtaa cttaatgttc attccataga tactgccgac
    16801 gattgtcggt atagttaaaa taatcgttaa agaagttaaa attttcataa tattattcag
    16861 attattcgat acgattgctg aaaaagtctg attcatttgt tctactagtt ttaattgaat
    16921 gcgagaagta gtcattgcct gctctgtttc caccaataca tcacgtaaat gatttttcaa
    16981 agcatgattt tcttggaaaa gtttattttg cgctagttct ttcaatgcat ctaaattagc
    17041 agaagtcgct tctctgaaat aaacgaggct tttttggata tccatgattt gataaagttg
    17101 tttgttttca gtggatactt gaagtttggc ttccaaagta tcgcattgag attgaagcgt
    17161 agctaaataa ctgttgtaag agagtgtgac ctgccaaatg aattgaaaga agatattgag
    17221 attaggcgaa atatcacttt ttggaaaggt ctggctaaag actttcttta aaaacagtgg
    17281 ttcatgattc gtaattgtga taagcttctt tttgggcgtc aaaataatag agagcgggta
    17341 tgtatccact tgaaaataac cgctaggact tgttttagca aaaggatatt gtaacaataa
    17401 taacgctggc tttgtcaact ttgattgatt gaattcttct gtacgggaat tttctgcatc
    17461 gtccaatatg gaagtgatgt aatctgacgg aatttcaaat tgatgtgtca gctgatgaat
    17521 ctcttcttga ttaggacgtt ctacacaata ccagatcgtt tggtcagttt cctttccggt
    17581 attacgcagt ttctcattat ctaatgtaaa atatttgatc atgattttcc tcctgttgcc
    17641 tgtttctttt attataacgg atagggaatt ggaatacatg gaatgtgttt gtaagatata
    17701 gaatataact gcataaattt aaataaaatg aaacagttgt gtaaagtata tacagtatac
    17761 ttgaagcaac gataaaaaag gagtttacgt tcatgggcac attcacacca cttatcttgt
    17821 tttggtatat ttacccggta atcgttttgt ttggttgcca atttcttgta aaattatttt
    17881 cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc gattcctttt ttgtggggcg
    17941 gtatgcatgc attgtctaga aatacaggga caatttctat cttaccgttt ttctttattt
    18001 ctgttttgct aatgggaatt tgtattgctg ttttccaagc atattattat gaagaaatta
    18061 tttatccgcg ttatttcaag atgacttggc gtttggtttt tctgttgaca atcgtcttgt
    18121 acgctgtctt gatcattgtg aacatacttt cttacctatg aaaaaaatag aaaagctgta
    18181 aaaagtcttt taaaaggctt tttgcagctt gatttttaaa aaaatgttta tgaataaaaa
    18241 aagttgttcc cggatttccc agaaaaggtg gtagaaagtg ggggattgtg gtagactaat
    18301 tttagttagt ggaggaatgg ggggctttca atgttgatgg gtgaattcca acataatatt
    18361 gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg aagaacttgg cgaaaagttt
    18421 gttctgacac gcggattgga tggctgtctt ttcggctatc cgatgagcga atgggaaaat
    18481 ctggaagcta aactgaacga aatgccgttg gctaaaaaag acgcacgtac ttttgtgcga
    18541 ttcttctatt cggctgccac tgaatgcgaa cttgataaac aaggacgaat caatataccc
    18601 agcacgttaa gaaattatgc agctttgaca aaaggttgcg tagtcatcgg tgtatctaac
    18661 cgaattgaaa tttgggatga gacacgatgg caagattttt ctgcagcagc agaagagaac
    18721 tttgacgaaa ttgctgaaag tatgattgat ttcggactat aagaatagga agaggctgac
    18781 taatgactga aacatttcaa cactatacag tcatgttgaa agaaacggta gatggattga
    18841 acatcaaacc ggatggcgtt tatgtagact gtacactcgg cggtgccgga catagtgaat
    18901 atttattaag ccaactaagt tctaaagggc atctgtatgc gtttgaccaa gatcaaaaag
    18961 caatcgatca cgccaagctg cgtttagctt cttatgtcga acaaggtatg gtcacattta
    19021 tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga gcatgtagat aaggtagacg
    19081 gcattttgta tgatctaggg gtttcctctc ctcagctaga tgaagcagaa cgtggattta
    19141 gttatcatca agatgcaccg ttggatatgc gcatggatca gtcagctcct ttatccgctt
    19201 atcacgtaat taatgaatat tcctaccatg aattagtaaa gattttcttc cgctatggcg
    19261 aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg agtacgaaaa acaaaaccaa
    19321 tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt catcccagct cccgcaagaa
    19381 gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt gcggattgca gtaaatgacg
    19441 aactcggtgc cgaagaggcc tctttagaac aggcaatccg gttattgaaa gtcaatggaa
    19501 gaatcagcgt aatcacattc cattcattgg aagacagaat tgtcaaaagt atgtttaaag
    19561 aatatagtac ggtacaagat ctaccaccgg gacttcctgt catacctgac gaattccaac
    19621 cagaactgaa agtcattact cgtaaaccaa tccttccttc agaggaagag ctaacagaaa
    19681 acaatcgatc acgcagtgca aagttacgta ttgcagaaaa aataagaatg aaagaggagt
    19741 agaatgatgg cagaattaaa gaaaatgcaa gattacgaat atgatttacc tgaattggtg
    19801 gatcagccgg aacaacaaat gcctgattct tcttcgaatc aagaaatcat tcttccacaa
    19861 tcaccggcaa aacgattaaa gcagatttct gctttggaaa aaattgctgt ggcaagcgtg
    19921 gcgattgcta ttgttgcttt atgtgtttta acagttatgc tgcgcacaaa tatcagcgga
    19981 gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg ataaaaagca agaaaaaacg
    20041 agtttagaac aagaaaaaaa cgaactttct cgtactgaac ggattaaaca aatcgcagaa
    20101 gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag tgaagtaaat gagtcttaaa
    20161 aataaaattc ggcggtttat ggaaaagaaa aatctaaatc cgatgaacaa tcgcaaaaaa
    20221 gtaggtatca ttttatttgc tacgagtatt ggattgttct ttttatttgc cgtccgtttc
    20281 tcgtatatcg ttattggagg tcatgttgct ggtacctcat tagctgaaaa aacaaaacag
    20341 ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa cgatttatga tcgtaacggt
    20401 gtggcgctcg cagaagatgc ctcctcttat tcaattaaag cgatactctc aaaaacatat
    20461 acctctgggg ataaaaaact gtatgttgaa gaaaagaatt ttgataaaat agcagaaatc
    20521 ctgcataaga atctttctat agacaaaaaa gatgcactga atattttaga ggacggcgca
    20581 aaaaaagagc tgtatcaagt tgaatttggt agctatggga aaaatatctc ccaagaaacc
    20641 aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg ctggtcttta ttttgtcgac
    20701 catcaggctc ggatgtatcc aaatggcgtc ttttcttctc attttattgg atacgcagtt
    20761 ccagacaaag atgagaatgg cttagttggt aaactaggtt tggagtctgc ttacaatgat
    20821 atcttgagcg gtaaagatgg taagattatt tatcaaaaag ataattttca aaatcctctg
    20881 ccaggtacag tggcagaaga agaaaaagct gtcgacggac aagatatcta cacgacttta
    20941 gacagcagac tacaaagtta tttagaaaca ctgatggatc aagtaaatga agaatatcag
    21001 ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg gagaaatctt ggcaatggga
    21061 caacgaccta ctttcaatcc tgaaacaatg gaaggattga ctggaaaaga tgctatctgg
    21121 cgtaatttct tggtacaaga tagttatgaa ccaggatcaa ccatgaaagt tttcactact
    21181 gcagctgcta tcgaagaagg agaattcaac gagaatgaaa ccttccaatc tggaaaaatc
    21241 caagtagaag atgctacgat caatgaccat gactttggtg aaaaaggtgt gctgaccatg
    21301 cgtcaagctc tttcatggtc aagtaacgtc gggatggtca tactggaaca gcgattaggc
    21361 ggacgatggt ataactattt acaaaaactg ggatttggac aaagtactca ttctggatta
    21421 gatgatgaag taaacggtgc tttacctaca ttaaatattg tcgaccgagc aatgagtgct
    21481 tatggacaag cggtaggtgt gacgaatttc caaatgatga aagctttcac ttctattgcg
    21541 aataacggta caatgattca acctcgatat atcagcaaag tggtggatcc ccaaactgga
    21601 gaagagcgaa caactcaaac agaagttcta gggcaacctt tttcaaaaga aacaacagaa
    21661 aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa actacggtag tgcttatggt
    21721 gtatatagtg tacctggata caatgtatcg gcaaaaaccg gaacagccca aatcgcttct
    21781 gatacagggg gatatcaaac aggagataca gcctacctgt attcgattgt ggagatggtt
    21841 ccttctgaag atccagacta tgtcttgtat ctaacaatga aacaccctaa gacatatgat
    21901 cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac gggcaatgga ttttaaagaa
    21961 actgaagaag attcagatac agaaacaaaa acagaaaaag tatccgtagc cgattatcgt
    22021 aatcttgaag cggacgttgc agcagctgat gctcaaaaaa gtggactgca acctgtagtg
    22081 atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca acggtgatca gttgatctct
    22141 ggagaaaaac tgatcctata tactggtggt gataagctga tgcctgacgt aacaggatgg
    22201 tcaaaagcag atatcatgaa gctggggaaa atcctcggta ttgaagttag ttttgatgga
    22261 gatggttatt gtgtcaaaca agaacttgct ccatatgaaa aaatcactga agacaaactt
    22321 agttttactt tagaagaata agaagagaaa taggagagaa aagagcatgg aatggacaca
    22381 agcattgatt cccattgtca gcagttgtgc aatgacaatt gccgcaatgc cgctatttat
    22441 tggttatttt caaatgaaaa agcaaggtca ggcgattcgt gaggagggac caaagtggca
    22501 caatagcaaa gccggaactc ctacaatggg cggcttagtg tttctgatcg gctctatttt
    22561 gacaggaatt tgggttggag cttggcaaaa acagctaact cctactcttt tcatcttgct
    22621 ttttgtatta gcgttatacg gagtaatcgg ctttcttgat gattttataa aaatattcaa
    22681 gaaaagaaac atgggactga actcgaagca gaaattgatt ggacagattc tagggggaat
    22741 catcttttat cttgtttacc gttctgaagg ttatccaggt gtattgaatt tcttcggact
    22801 agatctacct ttaggaatca tttatggtat tttcgctctc ttctggcttg ttggattttc
    22861 aaatgcagta aatctgacag atggcatcga tggattagtt gctggcttag gaagtatctc
    22921 ttttgcagct tacggtctaa ttgcttggca tcagcatcag tatgatgtat taatcatttg
    22981 cttaagtgtt ttaggaggtt tactgggttt cttcgtctac aacagaaaac ctgccaagat
    23041 ttttatggga gatgtcggtt cattagcgtt gggcggactt ttagcggcaa tttctataat
    23101 gctaaaccaa gaatggacat tgcttttgat tggtttgatc tatgttatgg aaacagcaag
    23161 tgtgatgctt caagttactt cctttaagct tacaggaaaa cgaattttta aaatgtctcc
    23221 aattcatcat cactttgaaa tgtgcggatg gtcggagtgg aagattgata cagttttttg
    23281 gttgatcagc attgtgactt cgttgatcac attatggatc gtttggtagg agatgacggg
    23341 aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct tgtcttagga ctcgcaaaaa
    23401 gcggagtaag tgcggccaaa ttattacatg aattgggcgc acttgtcacc gttaatgatg
    23461 gaaaaccttt tgacgaaaat ccggaagcac aagagctgct ttctttaggg ataaaagtaa
    23521 taacaggtag tcatccaatc gaattgttgg atgaagaatt ttcattgatg gtcaaaaatc
    23581 cagggattcc ctacagtcat cctttagtag caaaagccca agaaatgggt attccggtaa
    23641 ttacggaagt tgagctagct tacgaagtag cggaatgccc aattattggg attacaggaa
    23701 cgaacggaaa aacaacgaca acaacgatga caggactact actgaatgca ggagcagatc
    23761 aaggaattgc acgtttagcg ggtaatattg ggtatccagc aagtggtgta gcgcaagaag
    23821 caaaatcaga agataaaatt gtgatggaat tgtctagctt ccaactcatg ggaatcacag
    23881 atttccgccc tcatatagcg gtgattacca atatctatga agcacatatt gattatcatg
    23941 gtacaagaaa agaatatgtc aaagctaaat ggaaccttca aaaaaacatg acagaaaaag
    24001 attatctgat ccttaactgg aatcagtcag aactacaaga attagcgcaa agaacaaaag
    24061 cacgcgtact gcctttctcg acaaaagaag tgttggaaga cggtgtgtat gctgacgatt
    24121 actcaatata ctataaaaaa gaaaaaataa tggaaatatc tgaacttggc gtaccaggta
    24181 agcataatgt agaaaatgca ctagctgcta tttctgtagc aaaattgtat ggtatatcaa
    24241 atgaagctat acgagaaacg ttgcattttt tccatggcgt accacatcgt acgcaatatg
    24301 taggagaaat ccaaggcaga aaattttata atgattcaaa agcaaccaat attttagcga
    24361 ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt gttattggct ggcggattag
    24421 acagaggaaa tacatttgat gaattaattc cttcattaaa aggaatcaaa gcaatggtcg
    24481 tatttggcca aacaaaagaa aagttgatgg atgctggaaa aaaagcaggc atcgagacaa
    24541 tagtaacagc cgattctgta gaacaagcag ttcctttagc attagaaaac agtacagatg
    24601 gtgatgtagt tttattatca ccagcgaatg ccagctggga tcaataccca aattttgaaa
    24661 ctagaggaaa cagattcatg gaagctgtga accgattaaa atagaaaaag tagaagcgag
    24721 cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag ggggacatat ttatccagct
    24781 cttgcctttg tcaattatgt aaagactcaa gaaccgaatg ctgaattcat gtatgtggga
    24841 gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag gaatgccttt ccataccttg
    24901 gagattcaag gatttaaacg aaaaatttcc atgcataaca tcaagacggt ccgattgttt
    24961 cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt ttcaaccaga tatcgttatc
    25021 ggtactggag gatatgtttc cggagcggta gtgtacgctg cagccaaaat gggtattcca
    25081 acagttatcc atgaacaaaa cagtgtacca ggtgttacca ataaattttt aagccgatat
    25141 gtggatcgga tcgctctttc atttaaagat gcggcttcct tttttcctga aaacaaagca
    25201 gttcttgtag gtaatcctcg agcacaagaa gtagcagata ctaaaaaatc agatattttg
    25261 aaaacatttg atttggatcc agaaaagaaa acagtcttga tttttggcgg tagtcaagga
    25321 gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg aatatattcc ttcttcttac
    25381 caagttttgt atgcttcagg agatagatat tatgaagaga tcctaaataa aataaatcct
    25441 gaaatacaaa atattagtgt ccagccttat atcaaaaata tggcagaggt catggcttcc
    25501 agtgatctgc tggtggggcg tgctggtgca acttcgatcg cagaattcac agctctgggg
    25561 ttaccggcag tgttggttcc cagcccatat gttacgaatg atcatcagac taaaaatgca
    25621 atgagtcttg ttcacgcagg agcagcaaaa atgattgcag ataatgaact aacaggtgaa
    25681 tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag aattgcaaaa gcaaatgtgc
    25741 cgagcttcta aagaacaagg aatccctgat gcttcaaaac gtctttatga cttagtaaaa
    25801 caaataatca aaaaataaag gcggtggtct tagtgagtaa gaaaaaagaa ccaaaaaaat
    25861 tgtctcatcc gtcttctgat gaaaacaatt tgactccttg gcaaaaggct aaccgaaaat
    25921 atctggcaga acaagagatg aaaaaccaag agccaaaaaa agaagacata acattagata
    25981 cacccctttc agattctgaa gaagaaaaaa cggttcaaga ggaacagcaa gaagaaagcc
    26041 agtccgagaa aaaaatcgaa ttttttgaag agatcaagca aaagaaaaac ggtggaccat
    26101 ataacggttc ttttttgaac cggctgccca atttaaaaag tcaacggcac aaagtactat
    26161 ttcgtcggtt agctttgatc atcactgtat tgggtatacc gctgattttt ttgatctatt
    26221 atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc aggcaataag acagtcaaca
    26281 gccaagaaat catctctgat acaaaattgt cattaggaga aaatgtttgg ggacagtatt
    26341 ttcatcgatc tacttatatc gatcgcctta aaaaagcaca gccaagaatc gaaacagcaa
    26401 atatacattt caaagggatg aatgaattcg atttggatgt aacagaatat aaagagattg
    26461 ctttgatcgc aaaaaacaat caatactacc cagtgattga aaatggaaca gtattagatg
    26521 aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga agagttcaaa gactctgcaa
    26581 aaatcaaaga attaacaaag caatacaatc agttatcatc agaattacaa aaagcaattt
    26641 ctgaaatcaa gtacacgcca agagcaagca ataaaaatct gatccaattg aatatgaatg
    26701 acggcaatca agttattgta aatatcaata atcttgcgaa ccaaatgaaa tattattcgc
    26761 aagtagccaa agatatggat gaaaaaggtg tgatcgacat ggaagttggt atcttctcgc
    26821 atccttacgg tagcactcaa gaaacggaag aatcgggcca atcggaagaa acaactgaaa
    26881 gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga ggcagaaacg caaaaagcac
    26941 aaacacctgg atcgtctagc acaaacggat catctgattc aaatgattca agtgaaacaa
    27001 gtcaaataga agataatcca agtacaactc cgtcaagttt aaatgaaaat tgataaaaca
    27061 actttaaaaa gtaagaatgt actttctaaa aaccagtaat ttatggtaga attggaagca
    27121 gtgaatatat ctattaataa gtatatttta aaacggacgc tagttgttcg cttgtatatg
    27181 gaatagtaag taggagggaa tcccattcat ggcaaaaaca ggaatgtatg taggccttga
    27241 tattggaacg acatctgtta aagttgtcgt ggctgaatat atcgacagcc aaatgaatat
    27301 tattggagta ggaaacgcaa aatcagaagg gattaaccga ggcattatcg ttgatatcga
    27361 taaaacggtc caagcgatac aacgagcagt acgacaagca gaagaaaaag caggtatcca
    27421 gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt gaagtagaaa attgccaggg
    27481 aatgattgca gttaacggag attcaaagga aatcaccgat gaagatgtca gaaatgtggc
    27541 ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa atcgtgtcaa tattgccaca
    27601 agattttact gtcgatgggt tcgagggaat caaagatcct cgtggaatga tcggcgtaag
    27661 attagaaatg tacggtctgt tgtttacagg acctaaaacg atcatccata acatacgtaa
    27721 atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg attactcctt tagcgctgac
    27781 tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg atcgtcattg atatgggtgg
    27841 cggccaaaca acaacggctg ttatgcatga taagcaattg aagtttacca atcttgacca
    27901 agaaggtggc gaatttgtca ctaaagatat ctctattgta ttaaatacgt catttaacaa
    27961 tgcagaagcg ttgaaaataa actacgggga tgcataccca gaacggacat caccagatga
    28021 agaatttcca gtagatgtga ttggtcagtc agaaccagtg aaagtcgatg aacgctactt
    28081 gtcagaaatt atttcagctc gaatggaaca gattttcaac aaagcaaaag atgcattgga
    28141 ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg acaggcggag ctgctagtct
    28201 tcctggtgtt gtggacttgg cacaagaaat cttcggcgta aatgtaaaat tgtatgttcc
    28261 aaatcacatg gggctgagaa acccggtatt tacaaatgta ataagtatcg tggattattc
    28321 agcaaacttg agtgaagtgt atcaattggc aaaaattgct gttacgggtg aaacctcagc
    28381 agctcgtcaa atggtagttg aacaagaaac aacaaacaca tatgagagct atgaagcacc
    28441 tgaagaaaca atctacgatg agccggaacc aaaagagtcc ggagaaaatg taaaaaataa
    28501 aatcaagggt ttctttacaa atatttttga ttaattcatc ctgggaggaa taagatatgg
    28561 aattctcaat tgataataat atcaatgacg gcgcagtaat caaagtcatc ggagtcggtg
    28621 gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa cgttaaaggt gttgaattca
    28681 ttacagccaa cacagacgtg caagcattaa aaaattcaaa agctgaaaca gttatccaat
    28741 taggccccaa atatactcgt ggtttaggtg ctggttctca gccagaagtt ggacaaaaag
    28801 cggcagaaga aagtgaacaa tccttacgcg aagctttaga cggtgcagat atgattttca
    28861 tcactgcagg aatgggtgga ggaaccggta caggtgctgc accaatcgtt gcaggtatcg
    28921 cgaaagaatt gggcgcattg actgttggtg tcgtgacacg tccattcact tttgaaggac
    28981 cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt gaaagaaaat gtggatacat
    29041 tattaattat ctcaaataac cgtttattag aagttgtaga taaaaagaca ccgatgcttg
    29101 aagctttccg tgaagcagat aatgttttac gacaaggtgt acaaggtatc tctgatttga
    29161 tcacagcgcc aggttacgtt aaccttgact ttgctgacgt gaaaacagtg atggaaaacc
    29221 aaggtacagc attgatgggg atcggtgtgg ctagtggaga agatcgcgta gtagaagcaa
    29281 cgaaaaaagc aatctcctct ccattgcttg aaacatctat tgatggagct gaacaagtac
    29341 ttcttaacat cacaggcggt ttggatatga cattgttcga agcacaagat gcttcagata
    29401 tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct aggtacatct atcaatgaag
    29461 aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg tatcgatgaa tcaaaaaagg
    29521 aacgcaagtc tagccgacca gctagacaag cacaaatgca atcacctgct caaaagactg
    29581 tattagatat ggatcaagct aaaccaactt cttcagaaga agaaaacagt tttggcgatt
    29641 gggatatcag acgtgaacaa aatgttcgtc ctagagttga tgattccaat tttgacaata
    29701 tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac aaaatctcat ggcgatgatg
    29761 aattaaatac gccaccgttt ttccgtcgta aaaaataaag gagaggaaga gcacatgatt
    29821 gctgacaact tgcagaaaat caagcaagaa attcaggatt cgtgtgctct tgttcatcgt
    29881 gatccgaaag aagttacatt agtagctgta acaaaatctg ttgaatccgc tcaagctgaa
    29941 gaattggtta gagctggcgt tatgaattgt gcagaaaacc gagtagataa attattagaa
    30001 aagaaacaag atttatttga ttttcctgaa ataaagtggc atttaattgg taatttacag
    30061 cgcagaaagg taaaattgat tgtaaatgaa attgattact ttcatgcgtt ggacagttta
    30121 agattagcag aagaaatcca gaagcggtta gagaaagaat tatcctgttt tattgaagta
    30181 aatgtttctg gtgaggaatc aaaacatgga atttcaccag atgagctttt accgtttgtg
    30241 gaatctttag ctgcctgcac aaaaatcaag gttgttgggt tgatgactat ggcgcctaaa
    30301 gaagcttctg atgagcaaat ccataaagtg tttggtacgc tgaaagaatt gcgtgatctt
    30361 gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat taagtatggg gatgagtcaa
    30421 gactttcaaa ttgcgattga agaaggtgca acatttatcc gtgtaggaac agcgctattc
    30481 aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac agaggagcaa ttgctaattt
    30541 tttcggatta gctgatgagg aagagtacga ataccaagat tatcctgaaa caacaaaaaa
    30601 ggctgtacag ccaactaaaa aaaatacaac acagaatcaa tcaactcatt ctgtatctgc
    30661 tgcgaatact catgaaaaac aaaaaacggc gacttcacgt cctgtaacgc atgaaagtat
    30721 tcagccggct gaaaagaaaa aagtaattga actacatcaa tcacctacaa aaactgtagc
    30781 gaaagaaaga acagcttcaa gaacctctac acaacctaaa gcaaatcttg ctggaaaaat
    30841 cactgtaatg gaaccaagag cttattctga agctatggcg attgctaaac gaatcattgc
    30901 tggagaagca accttagtga attttcattt agtagaagaa aaacaagcga gaagaatcgt
    30961 tgattttcta acaggaacag tttatgcact agatggagat atcaaacgtg ttggagatga
    31021 gatttttctt tgtacaccga ctgggatgga gattgacagt tcaaccgctc aatcttttgc
    31081 agatgcgaat ttgtttgatc tgtaagagga ggaactacga tttatactat tgcactatta
    31141 cttcatttac ttcaacgggc agcctatttc tatagcatta tcttgatggt atatgcattg
    31201 ctctcttggt ttccaggcgg gtatcaatca gggctaggac gattattagc taagatctgc
    31261 gaaccgtata tcagtttgtt cgatcgtctg cctttgagga ttggaccctt ggatttcaca
    31321 attttagggg caatcctgat cttgaactta gccgtacaag gtttagcaca gatcgttata
    31381 tggataactg tccatttagt ttattgattg aagcaacaaa atctttattc tcagaataga
    31441 taggagggga aaattttgga tgcaaatgta taccagcact ttcgggcaga tgaacgtaca
    31501 tttatcgatt cggtaggcga ttggattgaa caggttcaag gacaatatgc accctatctg
    31561 accgaatttc ttgacccaag acaatcctat attttagaaa cactgattcg acaaagcagt
    31621 gatttgcgtt tcatgtttta tggcggatat gaacaggcag aaagaaaaag atgtttgatt
    31681 ttccccgatt attacgaacc tgtagaggaa gattttgaaa cagcattgta tgaaatccat
    31741 tatcctagca aatttgccag cctaagtcat gggaaaatcc ttggaacttt agtgggaacg
    31801 gggatcaaac gctcttactt tggcgatatc atctcggacg gtgatcgctg gcaagtattt
    31861 attgcaaatg aggtggatca ttttgttgct gcacaagtaa caaagattgg aaaggttgct
    31921 gtacgcttgg aaccaatcaa atacacagaa atgattatgc cgaaagatag ctggacacaa
    31981 gaaagaggaa cagttagttc catgcgacta gacagtgtga tctctgagat ttataatatt
    32041 tccagacagc ggtccaagca gctgatcgaa gctggtaaag taaaagtgaa ctggacagaa
    32101 aatacaagac ctgattttgt acttgaacta ttagatatta tttcagtcag aggttatggc
    32161 agagtccaga tccaagaact tgaggggaag acgaaaaaag aaaagtacag ggtactgttc
    32221 ggtgtattac gtaaataaaa taaaaaggtg gtttactcat ggctttaact ccattagata
    32281 tccaaaataa gacattcccg acaaaaatgc ggggatataa tcaagacgaa gtagatgatt
    32341 tcttagattt agttgttcgt gactatgagg aattgactca aagaaatcga gaattagaaa
    32401 aagcagtcaa acattctgaa gaaaaacttg agtacttcaa tgaattaaaa gatgctttga
    32461 accaatcaat catcgtagct caagatacgg ctgataaagt aaaaacaagt gcaagcaagg
    32521 aatccgaagt gatcgttact tctgcacaaa acaaagcaga tgagttagtt gcgaacgctg
    32581 aaaaacgtgc acatcaatta acaactgatg cagaagaaaa agcaagaaaa atcttgacag
    32641 atgcaacaga aaaagcaaga cagcttgcga cagaaactga agatcttaag aaaaaaacac
    32701 gagtattcca tcaacgtatc agcttgatgc ttgagtctca attagaacaa gtgaaaagtc
    32761 cggaatggga tgaaatttta caaccattct ccagctacgt gactgacagc catgaagtga
    32821 tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga tactgatgta aactcagaca
    32881 caggagtcat agaagcacct atgacggcat ttgatacaca ggctattgat atctcgatcg
    32941 tgcctggtga aaatgaaaac gagtagaaca gaaaagcact ttgttattct taaagcgagc
    33001 cgatgagagt ggaagttcgg taagacactg catggtgaaa gatcctctac ttgagacctg
    33061 cttttccgaa attagagtaa gaagcagcgg ctgacctcgt tattggtcac agagagtttg
    33121 cactagatag atgcaactaa atttgggtgg taccacggca tgttcgtccc ttgcggctga
    33181 acatgctttt ttgtgtccgg aaaacaaata aaggagtgta tggttgaatg aaaatgaaag
    33241 aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg taatttgcca aaccgagaag
    33301 gcgagtggca aaaagaatgg gaagaaaatc gaatctacca aaaaagacaa gagttgaacg
    33361 aaggaaaacc tagctttgtt cttcatgatg gacctccata tgccaatggt aatatccatt
    33421 taggacattc attgaataaa atcagtaaag acattatcat tcgttcaaaa tcaatgtctg
    33481 gctatcgtgc accatatgtt ccaggatggg atacacatgg attgccgatt gaacaagtat
    33541 tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc agaatacttg gaaaaatgtc
    33601 gtgaatatgc actttcccaa gtagataagc aacgagcaga tttcaaacgc ctaggagttg
    33661 caggagattg ggaacatcct tatgttacat tagatccttc ttatgaagct gcacaagtac
    33721 gcgtatttgg taaaatggct gaaaaaggct atatttacaa aggattgaaa ccaatttact
    33781 ggtctccgtc aagtgagtct tctttagcgg aagctgaaat tgaatataaa gatgtaaaat
    33841 ctccatctat ttttgtagct ttcaatgtca aagacggcaa agatattctt gatgaagata
    33901 cagcttttgt catttggacg acaacaccat ggacattgcc agcaaaccaa ggtattgctg
    33961 taaatccaaa atttacgtat gtattggtgg aagccgatgg ccgtaagttt gtcgtagcga
    34021 aagatttgct agaaacagtc caatcagaaa tcggttggga aaatgtaaca gttctaaaag
    34081 aatttgctgg acaagaaatg gaatatatga ctgcaagtca tccattctat gaacgtgaat
    34141 cacttgtgat tttaggcgat catgttactt tagacgctgg tactggatta gtccatactg
    34201 ctccaggaca tggggaagat gactatatcg ctggtagcaa atataaacta tctgtagtgt
    34261 cacctgtaga ctcaaaagga ttgtttacag aagaagcacc tggatttgaa ggtatctttt
    34321 atgacaaagc aaatcctatg atcactgatc tattaaaaga aaaaggagct ttgctgaagc
    34381 tagatttctt tactcatagt tatcctcacg attggcggac gaaaaagcct gtgatctatc
    34441 gggcaactcc acaatggttt gcatctatcg ataaattccg tcagaatatt ttggatgaag
    34501 tagaaaaagt agagtgggtt atcccatggg gtaaaacacg tttgtataat atgatccgtg
    34561 accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg agtaccactt ccgattttct
    34621 atgctgaaaa tggagaagca atcatcacac cagaaacaat cgaacatgtg gcaaaattat
    34681 ttgctgaaca tggatcaatt atctggtttg aaaaagaagc gaaagaactt cttcctgaag
    34741 gatttaccca cccaggttct cctaatggcg aatttacaaa agaaaaagat atcatggatg
    34801 tctggtttga ttctggttct tctcatgaag ctgttttacg tcagcgacca gaattatcat
    34861 tcccagcaga tatgtattta gaaggatcag accaatatcg tggctggttc aactcaagta
    34921 tcacgactag tgtggctatc aatggtgtag caccatacaa atcagttatt tctcaaggat
    34981 ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt aggaaacatc attgcaccag
    35041 aaaaagtgat caaacaattt ggtgcagata tccttcgctt atgggtatct agtgtagatt
    35101 atgaagcaga tgttcgtgtt tctatggata tcttaagtca agtggcagaa gtatatcgta
    35161 aaatcagaaa tacgatgcgt ttcttattag cgaatacaga agatttcgat cctaaaaaag
    35221 atactgtttc gtacaatgat ttacgttctg tagacaaata tatgaccgtt cgattgaacc
    35281 aagtaatcaa agaaatccga gaagaagggt acgacaaata taacttcatg catatttacc
    35341 gtacagttat gaacttcttg acggttgatc tatcgtcatt ctacctggat tttgctaaag
    35401 atgtagttta tattgaagca gaagatgatt atcaacgtcg ttgcatgcaa actgttttct
    35461 atcaaacagc tgtagctttg acaaaattat tgactcctat cattccgcat acagcagaag
    35521 aaatctggtc attcctgaaa gaagaagagg agtacgttca gttaagcgag tttcctggtt
    35581 atgaagagtt tgcaaaccaa gaagaattga tggatacctg gactgctttc atggacttcc
    35641 gtgataatgt cttaaaagca ttggaagaag caagaaacag caaattgatt ggtaaatctt
    35701 tggaagcaaa actaactgtt tatccaaaac aacaagttcg tgaaatgtta aaagctttgg
    35761 atgcagatat tgcacaatta ttgatcgttt caccagacta ctttgaagtt atggcagcag
    35821 atgaacaagt gccagataac gctatggtat ttgatgatgt tgctattaca gtggaaaaag
    35881 cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa agatgtagga gtagatgaaa
    35941 aacttcctca tctatgcggt cgttgtgcaa aaatcgttga agacttctat cctgaagctg
    36001 tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg tgtgacatgt tctttgtcac
    36061 accccctttt gttatcaatc gtttaatttt ccacgttcac gataccagtt atctggttgc
    36121 cagatccatt cgaatccgtc tttttcaagt agttcgaaag ctgctttagg tcccattgat
    36181 ccagctttgt agttgggaaa atccggttgt gtttggtccc aagcttttcg aatgacatcc
    36241 acgatatgcc aagattgagc gacttcttcc caatgagaga agttcgttcc atcaccattc
    36301 aacgcatcta atagtaattt ttcgtaagct tctgggctat tttcaaccat ttctgcacta
    36361 tttctaaatt ccaatttgat tggttccgtt tcaaatcctt gccctacttc tttcccattc
    36421 aaggataaag aaaatccttc agttggctga atatagatcg ttagaacatt aggtggaagt
    36481 gtcgtatcgt cacatggttc atcgacagat gttttgaata cattaacagg aacttgtttg
    36541 aatacgatgt tgatccgagt ccctttttca gtcaaacgtt tgcctgtacg tacatagaaa
    36601 ggaacacctg accaacggaa gttatcgata gtgaatttgc ctgcgacgaa tgtttcagtc
    36661 tctgattgag catccacttt gtcttcttcg cgatagccct tgaattgtac accatccaat
    36721 tcaccttgag catattgccc gcgaacgaag ttttctaaca cttcttcttc gttataaatg
    36781 cggatagctt tcaatgcttt gatcttttct gtacggattt ctttttcgga aaatgctact
    36841 ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat gattttgcac catgtcttta
    36901 agtgcgccac tatgatcgta gtagcccccg cgatcttcta caccgaggtt ttcgccaaaa
    36961 gtaatttgga tattgtcgat atagcgattg ttccattgag cctcaaaaat attattggca
    37021 aaacggatag ctgagatgtt ttggatcatt tcttttccta aataatgatc aatcctgaaa
    37081 atatcttgtt ctgggaatac ttctctgatt tgctggttca attcaaaagc agactggtaa
    37141 tcagaaccga acggtttttc tatgatcaaa cgattgaagc cattttttgt cataatattt
    37201 tgtgatttca aatgagaaac gatcgttcca aaaaattgag gtgccatagc caaataatag
    37261 acacggttac cgtttaattg atagtgtcca tctaatcggt cagacaattc ttttaatgtc
    37321 tgataatgcg ttgaatcatt tacatcatgg gattgatagt aaaaatggct tgcaaaggta
    37381 gttgcttctt catctgaagg attcaatgca cggattgttt ctttgacaac ttcacggtag
    37441 tgctcatcgc tccagggacg gcgagcggtt ccgattacag caaaatgctc gcctaaattt
    37501 ccttttctgt aaaggcggaa caaagacggg tacaatttac gctgggctag gtcacctgta
    37561 ccgccgaata tcgtaaacaa tacatttttt tcattagaca tgtggataca ctcctttata
    37621 ttttatcgac aaaaatcgtg ctggccgcct taaagctgac ggggattttc tttctatcat
    37681 tttggatagt gatcggtcct tcataagctg cgatgtcaac gatctcatat tcttcgttga
    37741 tattcaggtc aatagtgact aagtaatcca acaattcttt ttcatcaagc actcgtgcga
    37801 tacgcacttt tgtaccgaca ggataggact ccaatgtttg tcggcgttct tcatggacaa
    37861 cttcctcttt tttaggaatc gatcctccat gaggacaatg ttcaggatga ttcaaatagt
    37921 tttctaaatg atctgcaaga tgttccgaag tcacatgttc caatacttca gcatcatcat
    37981 ggacttcatt ccagctatag tctaaatgtt caactaaaaa aacttcccat aagcgatgtt
    38041 tgcgaatcag actgctagct ttttgcagtc cgcttgcagt caattgtaca ccttgataag
    38101 gggaatgttc tacaagctct tctttcacaa gtttagaaat catttcactg acagatgcag
    38161 ctgagacatc tagactagat acgatttgtt tattgttgac tttcgttgta tctccaccta
    38221 gttctaaaat gattttcaaa taatcttctc gatttggtgt catattcgat catcctttca
    38281 tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg ttaattgact atttttctaa
    38341 ataaaaaaca aaggattttt agacgttttt acaacaaaaa acgaaagatg atagagaaga
    38401 ctcattcttt cgtttataaa ggatatatat atacattggg agggatctat ttttcagata
    38461 acaacttata tgaagtgtct gcagattcgt cataaagagt ttgttcggga taagaaaaga
    38521 taagataaaa accatactga tcacgtacga ctaaacgata ttcatctatt tctaccacag
    38581 atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc agatgtaatc tgtaattgtt
    38641 gtttttgctg gctatcacta aagaaccatg taccttgata ctttgagagt ccttctgact
    38701 tttccgcttg ttttttcttt ttcaagtaaa taaaacttga gagaacggta atgagtgaac
    38761 caagaaaata gatcattttt tttatcacca aatcactcct ttatgagaaa ataatcgcat
    38821 agacatattc tttcttcttt atttcattgt accgaataaa agctaaaatt tctctaagac
    38881 tttcgactgg tttttttact gtttttctac aaattatgat aggatacata gtaggaagaa
    38941 aggtgacata atttgaagta tcagcaagtg gaaatagctt tttttattga ccgcccgaat
    39001 cggtttatag cacattgtat gaaaaaagac ggagaaataa ttattgcgca tgtcaaaaat
    39061 acaggtagag gaaaagaggt cctgatacca ggcgctgaag tggctattgt atttgctcct
    39121 ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa aaaagaaggg tgactggttt
    39181 aatatcgata gtcaattgcc taatcggctg gcaattgatg gtattttaga cggcacgatc
    39241 cttttaccag gattaactgg tccatttacg gtatacaagc gtgaagtaac ttatcttcac
    39301 tccaaatttg atatttattt agagacggtg gtcggacaaa aagcatttgt tgaagtcaaa
    39361 ggtatgacac ttgaaaataa agcgattggt gcttttcctg atgcgcccac actcagagga
    39421 ttgaaacata taggagaatt aacgtatgcc gcacaagatg gttatgccgc ttatgtcttg
    39481 tttattgctc agttcgaaca tcttcatctg gcaacgatcc atgaagaaat gcaaccagca
    39541 ctagctgata tggttcgaca tgcgcagcaa agcggagttc aaatcctcgc ctataattgt
    39601 caagtatcgg cagatgaggt aactgtcaag caggccattc catttgatgt agatatccct
    39661 tttgaagatc ctatacaata gaaagaaggt aaaataatga tcaacttagg tattatcgga
    39721 acaaattgga ttactcatca atttgtccaa gcagctttaa gcacaaaaaa atatgaattg
    39781 acagcggtat attctagaca tttggaaaaa gcacaggaat ttggttctca ttatgaaggg
    39841 gatatcgaat tcgcaacaga tttgaagact tttttcaata ttactcatat ggacaccatt
    39901 tatattgctt ctccgaatag tcttcacttt agtcaagcta agcaagcaat tttggcagga
    39961 aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa aagaaatgga tgaaatcatc
    40021 catttggcaa atgaacacaa tgtgtatttt tttgaagcag caagaaatat ccatgaatca
    40081 ggttttaaaa agattgccga ttacttacca ttaaaagacg agataatcgg tgcaaatttc
    40141 agctatatga aatattcttc gcgctatgac caagtattag atggagaaga accgaatatc
    40201 ttctcgactc atttctcagg tggtgcattg atggatttag gtgtttacct tgtatatgca
    40261 gctgttgctt ggtttggaat gccaaaagaa gtccattatt tcccaagaaa gatttctact
    40321 ggtgtagatg gtcttggatg ggggatctta cgttatgaga attttgatgt atcgatccag
    40381 ccaggtaaaa tcggtgattc ttatttaccg tcagagattt attttgactc aggaacgcta
    40441 gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc atgatcgcgc gcataaagaa
    40501 atcattgatt tggcggtaac agctgcagaa aatccaatgg cagatgaagc agaggatttt
    40561 gccaatgtca tggctcatcc gaaagatcca gcttggggat tgttgtatga agagtggatc
    40621 gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa gaaaaaatgg cggcatcaaa
    40681 ttcgatgcag ataatgagga agatttttaa tgaacgaatt tgtacaagta tttcccgaaa
    40741 attggcagaa aaaatatgag gataaagggt ttatctcacc ttctcttatt caacgagcag
    40801 tttttcagcc actaagtaat aaacaaagta tagtagcggt ttctcctaca ggttcaggta
    40861 aaacactggc ttatctttgg cctctactac taaacgtgga accaggtgaa gcaagtgcgt
    40921 tggtcatttt tgcttcttct caagaactag ctattcaagt agcagatgtt gcacgtgaat
    40981 ggggaaaaga caaagagttg aaagtccaat ctttggtggg cggagccaac gtcaaacgtc
    41041 agattgaggg tttgaaggaa aaaccagaaa tcttgattgg tacaccagga agaatattgg
    41101 aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa aacaatggta tttgatgaag
    41161 cagaccagct atttgacgct gggaacagcc aaatcattga tcaaattctt catcaagctc
    41221 caacagagta tcagctagct tttttttcag cgacagcaga tcgttccctt gaaagcattg
    41281 aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac agcagaggac gattctcgaa
    41341 aaggactgag acattacttt ttacgtgtac cgatacgaaa gaaagatgac tacttgagac
    41401 gtctcacgca tatagaagat tttcatggtc tgattttctt taatcaactg actgaattag
    41461 gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt aggaagtctg gcctctgatc
    41521 agaacaagct actccgaaaa gcagcgctag aacaattcaa aaagaaaatg gtcagagcac
    41581 ttttgaccac agatgtggcg gctagaggtt tagatattac aggtcttcct tatgtagtga
    41641 atgcagaagt tccgttaagt gaagaagctt atttgcatcg ttcgggaaga actggtcgaa
    41701 tgggtaatga aggaatagta attacactcg tacaagataa taatctaaga gatttaaaac
    41761 ggcttttacg tccatcaaat ataacacttg aagagatttt tttatacgga ggtaagctgc
    41821 aaactgagca gccaaccaaa gaagatgcag ctcctgcagt aaataaaaag tatgcgaaaa
    41881 ctttttctgg aaaggagcag aacccagaat ataacaaaga aaaaataaga aaaaaagtta
    41941 aaaataaatc aaaaaaagag agaaataaag gagcaaggcg caaataagcg cctttttatg
    42001 ctatgattat gaaaacggga acaaaattgg ttgccagagg aggggttatg tgaaagaacg
    42061 tcaagaagag atcttgcagc tattgacaga aaaccaacaa ggattgacag caagtgatgt
    42121 agctgagcgc ttaactatcg atcgaagcaa tgcaagccga tatttaagtg aactatacaa
    42181 ggcccatcat attgtaaaaa ccgctggccg accagtcgtt tactctttgc caacggaaaa
    42241 gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa gtgacttttg aaacactcgt
    42301 tggagaaaat gattctttaa aagtcagcat acagcaggca aaagctgcga ttctttatcc
    42361 accgcggggg ttgcatacga ttatttttgg agaaactggt acagggaagt cgatgtttgc
    42421 tgaatgtatg tatcattttg caatcgattc agagatgctt tctgcagatg cgccatttgt
    42481 ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg ctctttggac acatctttgg
    42541 gatcaaaaaa ggggcttaca caggagcagc tcaagatagt cccggtctaa tagccaaagc
    42601 agacggcggt atattgtttt tagatgagat ccaccgttta ccgccggaag ggcaggaaat
    42661 gctgtttact ttcattgata aaggtattta ccgtccgctt ggagaaagtg cacaagtaca
    42721 tgaagcatct gttcagatca ttggggcgac gactgaatct tcagaaagtt tcttatctac
    42781 gttcaatcga cggattccta tggcaatcac cttgccgaat cttgcttcac gttcactgga
    42841 tgagcgttat gaaatcatct ctctttttat caaacaagaa gcgaatcgtt tgaatcaacg
    42901 tatcgatatc gaaaaagaag cgattcttgc cttcatgctt tatgatgcgg aaggaaatat
    42961 cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa tcttttttac attaccgtac
    43021 tcatcatgag aaaaagctaa tcattcgaaa agaagaactt tcccttcaag tacaaaaagg
    43081 attactgaaa atcaaggaaa taccggaacg tctcgaccga ttcatggaca gcaaaagtca
    43141 gtatttgaca tttgaaccag gatttgctga tgttgtctgg tcacaagatc cagaacgaaa
    43201 catgcaggtc tataacgata ttgaggaaaa agtcacttct ctttccgaaa ccggtgtgga
    43261 gaacattgat ctagagaccc tcatttcaaa agatgtggat gcttatttcc agacatatgt
    43321 caaagaattg actaaaagtt cgattcccaa agatcttttg ccagatgaaa tctggcggtt
    43381 aaccaatcaa ttgtatgatg tggctgaaaa acggttagac cgtatttata atgaaaaagc
    43441 tcgttttgct tttgctttgc atctgcaaag tacattggat cgtgtgagag aaggtcatat
    43501 gatcgtccac ccagatttga ataacgtacg gaaaaatttt aagagggaat tccaggtagc
    43561 aatcgatctt tcaacgatca ttgaagaaga agaacaagtt gagattcctt ttgatgaaat
    43621 cggctttatt agtatgtttc tttctatcaa tctaggagaa agtgagcctg ttaaagaaaa
    43681 caaagtagat gttctcatat tgatgcacgg cagacagact gcttcaagca tgttggagat
    43741 ggcacaagaa ctattaggaa caaaagtagg gaaagctttt aatatgccac tggttatgga
    43801 agttcaaaca atgtatgaag aagtgttaca atatgtcaaa aactatcaag agcatttgac
    43861 gaatggccta ctcttgttaa cagatatggg atcattaaac accttcagtg atttgattta
    43921 tgaagagact ggcattcgga cgaaagctat cacgatgaca agtaccatga ttgtgataga
    43981 agcgatacgg atggcaagtg ttggaagaag cttagaagat atttatcaaa atatccagct
    44041 ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa aagtctgaaa ctttacagcg
    44101 taaaaaagcc gtaatcgtga catgctttac tggtgaagga gtagctgcca aattatatca
    44161 gcgtattatg ccagtgatta atcaaaataa ggtagaactg atccagatgc agtttttaga
    44221 acgtgaatca ttcaaaaaac acatcgatgc cttattggaa gaatatgaga tcaaagcaat
    44281 tgcgggaaca gttgatgttg attatcaaaa tatcccattt ttttcagcct atgacgtttt
    44341 tgatgatgaa aaactaaata ttttaaagcg tatagctgat gatgagatcc cgacagctaa
    44401 aattgtcgat tcacttgctg gatcattaag cgatgtcttt tctattgatg aactgatccg
    44461 ttcattgcaa aagacagttc agcagatcca gaccgatttg tcgattatcg tggaacctgg
    44521 agtagatact ggaatcgtta tccatttagc cttcatgtta gacggattga tcaaacaaga
    44581 aagccatcgg caatttgaga aactgtctat tttctcaaaa atttatcgtt tggaaatgga
    44641 tatcgttcgg gcaaacttga tggcactaga acgaaaatat caggtaaaaa ttccagaaga
    44701 tgatatcgca tttcttacac aaatgtttct tgaaaataaa ataaaaaaat gaacacacta
    44761 atcatactgt ttacacacta aacatctgtg tgcgcactat aaaaaagagc taaaaagcat
    44821 gaaaacgcta tttcagctct tttttttatt ggcatgcttc ttgcgttata taaaagtgta
    44881 aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat catgttagtt tgttcagcag
    44941 ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc agcagaagaa aaagggatgg
    45001 aagccgatat ttttgcggtc tctgcctcag atgcagataa taatttagaa tctaagaatg
    45061 tcgatgtatt attattaggt cctcaagtac gtttcatgaa agctcaattt gaacaaaaac
    45121 ttgcgcctaa aggtattcca ttagatgtca tcaatatgca agactatggc atgatgaacg
    45181 gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata aatcaagtat gcagttgggg
    45241 gtataacaac gtggaagatc aacaaaatct agaagccatc atggggttaa tcatgtttgg
    45301 cggtaatgca aagagcgatg caatggaagc gattgcggct gctaaaatcg gtgattttga
    45361 gttagcggat aggaaaatcg ctgatgcaga agaatcactt atacaagcgc atcatgcaca
    45421 aacagacatg ttgacacaag aagcacaagg aaatcatatg caagtgacat tattgactgt
    45481 tcacagtcaa gatcacttaa tgacatctat tgcgtttact gatttagcaa aagaaatcat
    45541 cgaactttat cgtcgcgtat acagcgaata aatacaactt cttttttgaa cggaagaaga
    45601 aaaatttttg aacggatttt ttattttgtt ataaggagaa ctctctttat ataaaaaact
    45661 tataggagga agtaaaaaat gaacggacta tcaagttgga tggagaaata catcctgccg
    45721 gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt tgcgtgatgc ttttatcggc
    45781 acactgcccg caacaatggc gggatcagtc gctgtaatga tcaatgcaat tattcgtgat
    45841 ttaccgcaac agtttaacag tacctatgct gacagtttag cagcagacaa aggaatcttt
    45901 gccgtattga atgtcatcat cggaatcaat ggttttgtct ggaacggtac actagcaatc
    45961 gccggattga tctttgcctt ttcttggggg tataatcttg cccgagctta tggagtaaat
    46021 gatctagctg gggggatcgt tggtttagct accttgattc aaggtatttc ctttggtcca
    46081 gcattatcag cagcattaga tgtgaatgtt ccttcaaatg tcgcagatgc aatcaatagt
    46141 tctgagattg gtgcaacgat tgcagatggc acactgtcag ttggattatg gggttggcta
    46201 aaactagatc atttgaatgg aaacgcttat tttacagtta tgatcatggg agctatttca
    46261 gtcattattt tttgtaaatt gatgcttgcc aacattacga tcaaaatgcc tgattcagta
    46321 ccaccagcag tatctaaagc atttgcagcc attttaccag cgacgatcgc tttatacgtc
    46381 attgctatta tcaattatat cgtaggtcgt gtagctgatg ggcaactgat cattgatttg
    46441 gtgcaaaaat atattgcaga accattccta ggattatctc aagggttggg agcagtattg
    46501 atcgtcacag tatttgttca agtattctgg ttctttggta ttcatggatc aaatgtattg
    46561 gcaccagtgc tagagggaat ctggggacaa gcacaactaa tcaatattga tattttccaa
    46621 aaaggttata acggaaaaac tggtacacca gccgtgttag atgcaatcga agatggaaaa
    46681 gcttatatgt gggtccgcgg atcgttcgat gcttttgcat ggtttggcgg atcaggcgga
    46741 acgatcgtct tactgatagc tatcttgatt ttctctaaac gtgcagatta tctaacagta
    46801 gctaaattat ccattgggcc tggtatcttc aatatcaacg aaccagtgat gtttggtctg
    46861 ccaatcgtat tgaatgcaat catgtttatc ccattcttga ttgctccagt agtagcaaca
    46921 gcaattggat ggacagctac ttatcttggc ctagtcgctc cggtatcgca gcaagtcaca
    46981 tgggtagtac cgccgttctt attgtcattc ttagcaacag gagcggattg gcgggcaccg
    47041 atcgtaacat tagtatgtat ggtcgtgact ttcttgattt gggcaccatt tgtcatctct
    47101 gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag atgaacgtga ggagcgggac
    47161 gctttaagtt tcgttcctca taatgaattt tcgaggagga actgaaatga ttacaattgc
    47221 cagtgcaatg caacaagatg aaatcaaaga attgttagaa ggatacaatg aagaaggaat
    47281 gacttttaca tttaaagaaa aacaaggaat caagctgttc tttgaaacaa gtgcagaaga
    47341 tccggaagtt gcggctaaaa aagcaaagga actaatcaaa gcacagcctt ggggaacagt
    47401 cctttatttt caatcaacag ctgtttagaa aatggtttaa aaagatagga tggttgagat
    47461 gataaaaaac ggtttatttt tatgtagtat tggttctttg atcgtgttgt atagtttgaa
    47521 tccacattcg caaaggtatg atttgtatag tatggtcaca ggtctttttc taacaggatt
    47581 aggaatctat ttcttcatga aggggaaaaa aagagaagaa gcaaaggaga aaaataacta
    47641 atggaaatca cgaaaaaatt aaatattcca gcatcgtttt tttacgataa agttatggac
    47701 tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag taactagaaa acagctgaaa
    47761 aatttggagt acgtcaaaca attctcgcaa aataaccggg ctcgcataaa aatcgaagaa
    47821 gtcattgaaa accagtctta taagtttcgt acatcgacaa cgaagaatga attcgtcgtt
    47881 cattatcaaa tcaaaccatt ggacgattcg acctgtgagg ttcattacac agaaaaaatg
    47941 gagtcttatg gcatgcttca aaagttgaat gatatgcttt taggaacaat cttgatgtat
    48001 tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg aagcaacgta ttaaatcaat
    48061 gaaacatggt actatttagt tattgaaaaa tgaagtaagc tagaaggaat ttttcatagg
    48121 aagatagatc tttcctgcga atcctcacta gcttttttgt aggaaggggc agcaaaatga
    48181 caaacaaagt aagagagcta ggtgtatctt cgattgagga aatgtttgat ttagccactt
    48241 atgcatttaa tggggcagat acacctgaaa ggcgagaacg ttttcgtaca cttgcggaga
    48301 attcttggaa ttacggattt tttgatgagg aggatcggct aacaagtcaa gtcatggcga
    48361 ccccttttcc agtgaatttt tacggacaag agtacctaat ggccggcatt ggctatgttg
    48421 cttcttatcc agaagcaagg ggacaaggcg ggatcaatca gatcatggaa aagatccttg
    48481 aagattgccg tgatcgtaaa gtaagcttat cttatctggc gccattctcc tatcccttct
    48541 atcggcgcta tggctatgaa caatcatttg ataaaatcag ttatcaacta aacagtcgtg
    48601 atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg tatggatttt gaagatgcaa
    48661 aagctgcaat cagaagaatt tatgaacaga tgccggaaaa ccaacgagct ggtctgaagc
    48721 gcgaagactg gtggtatacg tataaattca agcaaaaagg caattaccag tttgctttgc
    48781 attttgatga taatgaggaa gcaacgggat atatcgttta tcagcttgca acgtcttcct
    48841 ttattattgc ggagtgggga tttttggatc atgatgcttt ttgcagcctt gttcgcttcg
    48901 taagttctca caatggtgct tttgaaacat ttgaatattc atgcggctac ggcggtaatg
    48961 atcaaaatta tctattagaa aatccatttg cttctgtaat gatcacacct tatatgatgg
    49021 cgaggatcgt agatatttct ttgtttttgg aaaattatcc atttaaaaag agacaagctg
    49081 catttgccct acaaatagaa gaagatcatt atgcgaaatg gaatgaagga atcgtggaag
    49141 taacaatcga aaatggaaaa aatcatctct caaaagtaga acaaacaaaa ctcccaatcg
    49201 ttcgaggaag tatccaacat atcacgcagc tattattagg gtatcgtaaa gtggaagagt
    49261 tggtattcca agaaagaata caggtgacaa aagaatatga agaaacgtta agctcaatct
    49321 tgccacagca acagccaatt cttaatgact atttttgata aaaaacgggt gatgacaata
    49381 tttttgtcac cacccttttg tttttcattt ggcatttgaa ggaaaatgtt aaagtaaatc
    49441 ctcttttttc gtaaatttga attttttgtt ttcttttgtt ttagggtttt cttttttgtg
    49501 gtcttggatt gcttctttcg taatcttttc ccgatttttt ttagatgaat ctaagcgttc
    49561 tgcgtatact ttttcttttg gcttatcatt cattggaaag gacctcccta cattatttca
    49621 ttctacctct agtttatcat ctgttaagga ctagtggaaa cgttttgcct aacttataag
    49681 ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa caagctacaa ttgatttatt
    49741 gaaattgttc ctgtagctca gtaggataga gcaatcgcct cctaagcgat aggtcgctgg
    49801 ttcaattcca gtcaggaacg tacaaataac ccctgtatcc tttgcggtac aggggg
//
LOCUS       DAPBBR010000020        47854 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPBBR010000020 DAPBBR010000000
VERSION     DAPBBR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.020"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(38..1189)
                     /locus_tag="RD488_001173"
     CDS             complement(38..1189)
                     /locus_tag="RD488_001173"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDT7657261.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="RD488_001174"
     CDS             complement(1202..1639)
                     /locus_tag="RD488_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7657262.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="RD488_001175"
     CDS             complement(1654..3420)
                     /locus_tag="RD488_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDT7657263.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="RD488_001176"
     CDS             3684..4361
                     /locus_tag="RD488_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657264.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="RD488_001177"
     CDS             4364..5491
                     /locus_tag="RD488_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657265.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="RD488_001178"
     CDS             complement(5691..6131)
                     /locus_tag="RD488_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7657266.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="RD488_001179"
     CDS             complement(6142..8175)
                     /locus_tag="RD488_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7657267.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPVSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="RD488_001180"
     CDS             complement(8177..9880)
                     /locus_tag="RD488_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7657268.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="RD488_001181"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="RD488_001181"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDT7657269.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="RD488_001182"
     CDS             complement(10963..11988)
                     /locus_tag="RD488_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7657270.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="RD488_001183"
     CDS             complement(12197..13066)
                     /locus_tag="RD488_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HDT7657271.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="RD488_001184"
     CDS             complement(13525..15417)
                     /locus_tag="RD488_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657272.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="RD488_001185"
     CDS             complement(15414..17141)
                     /locus_tag="RD488_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657273.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="RD488_001186"
     CDS             complement(17157..17807)
                     /locus_tag="RD488_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7657274.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="RD488_001187"
     CDS             18011..18307
                     /locus_tag="RD488_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7657275.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="RD488_001188"
     CDS             18479..19099
                     /locus_tag="RD488_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDT7657276.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="RD488_001189"
     CDS             complement(19191..20357)
                     /locus_tag="RD488_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7657277.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="RD488_001190"
     CDS             complement(20369..20722)
                     /locus_tag="RD488_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7657278.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="RD488_001191"
     CDS             20850..21872
                     /locus_tag="RD488_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDT7657279.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="RD488_001192"
     CDS             21891..22052
                     /locus_tag="RD488_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657280.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="RD488_001193"
     CDS             complement(22311..22745)
                     /locus_tag="RD488_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657281.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="RD488_001194"
     CDS             complement(22855..24714)
                     /locus_tag="RD488_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7657282.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="RD488_001195"
     CDS             complement(24832..25992)
                     /locus_tag="RD488_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDT7657283.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="RD488_001196"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="RD488_001196"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDT7657284.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="RD488_001197"
     CDS             complement(27739..28437)
                     /locus_tag="RD488_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7657285.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="RD488_001198"
     CDS             complement(28394..30055)
                     /locus_tag="RD488_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDT7657286.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="RD488_001199"
     CDS             30273..31673
                     /locus_tag="RD488_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HDT7657287.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="RD488_001200"
     CDS             complement(31925..33004)
                     /locus_tag="RD488_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7657288.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="RD488_001201"
     CDS             complement(33090..34049)
                     /locus_tag="RD488_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7657289.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="RD488_001202"
     CDS             complement(34061..35572)
                     /locus_tag="RD488_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7657290.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="RD488_001203"
     CDS             complement(35594..36157)
                     /locus_tag="RD488_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDT7657291.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="RD488_001204"
     CDS             complement(36163..37026)
                     /locus_tag="RD488_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7657292.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="RD488_001205"
     CDS             complement(37040..37936)
                     /locus_tag="RD488_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7657293.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="RD488_001206"
     CDS             complement(38111..39400)
                     /locus_tag="RD488_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7657294.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="RD488_001207"
     CDS             complement(39372..40889)
                     /locus_tag="RD488_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7657295.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="RD488_001208"
     CDS             41087..41977
                     /locus_tag="RD488_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HDT7657296.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="RD488_001209"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="RD488_001209"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDT7657297.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="RD488_001210"
     CDS             complement(42886..44358)
                     /locus_tag="RD488_001210"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDT7657298.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="RD488_001211"
     CDS             complement(44995..45357)
                     /locus_tag="RD488_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7657299.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="RD488_001212"
     CDS             45580..46332
                     /locus_tag="RD488_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7657300.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="RD488_001213"
     CDS             complement(46472..47395)
                     /locus_tag="RD488_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7657301.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="RD488_001214"
     CDS             complement(47410..47682)
                     /locus_tag="RD488_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657302.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13927 a         9946 c         8259 g        15722 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac cccggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcac
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccc tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcagttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agggttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcttt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcgtaggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaagttta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactcct tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacattt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt atcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata tcagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggattaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt cgtgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tctcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttatgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctctttcatt attaccaaag tctcttattt taaattgaat acattataat
    47821 gatactgtaa atatatcttt attattagtg aatg
//
LOCUS       DAPBBR010000021        42017 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPBBR010000021 DAPBBR010000000
VERSION     DAPBBR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.021"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            131..505
                     /locus_tag="RD488_001215"
     CDS             131..505
                     /locus_tag="RD488_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7657303.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="RD488_001216"
     CDS             complement(619..1248)
                     /locus_tag="RD488_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7657304.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="RD488_001217"
     tRNA            complement(1382..1454)
                     /locus_tag="RD488_001217"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="RD488_001218"
     tRNA            1668..1741
                     /locus_tag="RD488_001218"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="RD488_001219"
     CDS             complement(1879..2043)
                     /locus_tag="RD488_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657305.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="RD488_001220"
     CDS             2338..3666
                     /locus_tag="RD488_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDT7657306.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="RD488_001221"
     CDS             3868..4701
                     /locus_tag="RD488_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDT7657307.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKIEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="RD488_001222"
     CDS             4717..5454
                     /locus_tag="RD488_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HDT7657308.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="RD488_001223"
     CDS             complement(5609..6577)
                     /locus_tag="RD488_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDT7657309.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="RD488_001224"
     CDS             6809..7642
                     /locus_tag="RD488_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDT7657310.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="RD488_001225"
     CDS             7676..8515
                     /locus_tag="RD488_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7657311.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="RD488_001226"
     CDS             8541..9101
                     /locus_tag="RD488_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7657312.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="RD488_001227"
     CDS             9300..11021
                     /locus_tag="RD488_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDT7657313.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="RD488_001228"
     CDS             11186..12328
                     /locus_tag="RD488_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7657314.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="RD488_001229"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="RD488_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDT7657315.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="RD488_001230"
     CDS             14128..14775
                     /locus_tag="RD488_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7657316.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="RD488_001231"
     CDS             15168..17813
                     /locus_tag="RD488_001231"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDT7657317.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="RD488_001232"
     CDS             18123..19436
                     /locus_tag="RD488_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDT7657318.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="RD488_001233"
     CDS             19426..20079
                     /locus_tag="RD488_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7657319.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="RD488_001234"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="RD488_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDT7657320.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..22052)
                     /locus_tag="RD488_001235"
     CDS             complement(20700..22052)
                     /locus_tag="RD488_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7657321.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(22127..22906)
                     /locus_tag="RD488_001236"
     CDS             complement(22127..22906)
                     /locus_tag="RD488_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HDT7657322.1"
                     /translation="MAKICVICTDKIGALTGKIKLSDGNYVCKKCFSRAGFTSSIADV
                     QMVQSLSTEQIKTKFSSNSSNLSAKDIQKNRLEYFKKNSDLIIGDIIFNDKDRAFLIK
                     KSILMNRAQIIVKYDEIQTFTPIFLGGQIKKHHGITRALVGGALAGPIGALIGAGTGG
                     KEWESINRLGIEIYLKDNRIIKYDLISNETKINSLIGKNSFDQYNHLSAKLESILSNQ
                     TSTSVEITSQIDEIRKYKELLDEGIISQKEFNEKKKELLNL"
     gene            complement(23042..23794)
                     /locus_tag="RD488_001237"
     CDS             complement(23042..23794)
                     /locus_tag="RD488_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657323.1"
                     /translation="MNEKLFPQRLKELRAEKGITLEELAKKIGTTKTTLSRYENGERS
                     PKLQLVGLLANYFQVEMSWLSGQSDQRNSLNILPIYTQLSSPRQQKVYNFAKNELEEQ
                     NRSNVIQGNFGKAVDEDEKQEVSYVGLLSAGHGCPNYDKERPFGTVTMRESQIPSHYD
                     LAFMVNGNSMYPTFENGEIVFIKQTPNVMNGQIGAVEINGEAFLKKMYVENRRLRLVS
                     LNCECDENGNRLYPDFYADEYDDLYVIGRVIV"
     gene            23958..24191
                     /locus_tag="RD488_001238"
     CDS             23958..24191
                     /locus_tag="RD488_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657324.1"
                     /translation="MGKAFNRLKGLRAEKGLTQVEMAKLLGMNPDTYRKKENGERDFT
                     LREVATAQRVLGIDPQYYFFYKFSNQTVTERPA"
     gene            24491..24646
                     /locus_tag="RD488_001239"
     CDS             24491..24646
                     /locus_tag="RD488_001239"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657325.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            24803..24958
                     /locus_tag="RD488_001240"
     CDS             24803..24958
                     /locus_tag="RD488_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657326.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(24955..25179)
                     /locus_tag="RD488_001241"
     CDS             complement(24955..25179)
                     /locus_tag="RD488_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7657327.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            25257..25445
                     /locus_tag="RD488_001242"
     CDS             25257..25445
                     /locus_tag="RD488_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657328.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREARL"
     gene            25442..25600
                     /locus_tag="RD488_001243"
     CDS             25442..25600
                     /locus_tag="RD488_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657329.1"
                     /translation="MTLQEHQRLMQELNQEYHKDVKPELLGNQWRERQKKWREIKKDQ
                     LTMRVANW"
     gene            25635..25967
                     /locus_tag="RD488_001244"
     CDS             25635..25967
                     /locus_tag="RD488_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657330.1"
                     /translation="MNKKIENLIEELKKECDKENIGLSLSLVNEETFGMIAAGPANLA
                     VMGALLQGKEYIEIAAGNCHCEECKKIREVINAVDDEVSSTQHTFVINNKEDFADVMT
                     RIFKGEFE"
     gene            25964..26137
                     /locus_tag="RD488_001245"
     CDS             25964..26137
                     /locus_tag="RD488_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657331.1"
                     /translation="MIKINTLWIALFVFMLVVISNANLFVGCLFAGMITLLSLLEDFT
                     KKEGARHERVSKS"
     gene            26206..27147
                     /locus_tag="RD488_001246"
     CDS             26206..27147
                     /locus_tag="RD488_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HDT7657332.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSEATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEKGIK"
     gene            27149..28039
                     /locus_tag="RD488_001247"
     CDS             27149..28039
                     /locus_tag="RD488_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HDT7657333.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            28082..28882
                     /locus_tag="RD488_001248"
     CDS             28082..28882
                     /locus_tag="RD488_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDT7657334.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            28897..29748
                     /locus_tag="RD488_001249"
     CDS             28897..29748
                     /locus_tag="RD488_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7657335.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            29745..30104
                     /locus_tag="RD488_001250"
     CDS             29745..30104
                     /locus_tag="RD488_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HDT7657336.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            30119..30280
                     /locus_tag="RD488_001251"
     CDS             30119..30280
                     /locus_tag="RD488_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7657337.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            30277..30582
                     /locus_tag="RD488_001252"
     CDS             30277..30582
                     /locus_tag="RD488_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657338.1"
                     /translation="MSVDKKATMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            30582..30938
                     /locus_tag="RD488_001253"
     CDS             30582..30938
                     /locus_tag="RD488_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HDT7657339.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            30925..31143
                     /locus_tag="RD488_001254"
     CDS             30925..31143
                     /locus_tag="RD488_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657340.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            31164..31253
                     /locus_tag="RD488_001255"
                     /pseudo
     CDS             31164..31253
                     /locus_tag="RD488_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            31328..31795
                     /locus_tag="RD488_001256"
     CDS             31328..31795
                     /locus_tag="RD488_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HDT7657341.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            32070..32306
                     /locus_tag="RD488_001257"
     CDS             32070..32306
                     /locus_tag="RD488_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657342.1"
                     /translation="MYWRVYKMKIASEKIDQLTILVNQRIEDIIKEFEGEKIKNIKLT
                     LMDHKFELNSTKRKIVELIEEEIALQINEQQLAN"
     gene            32330..32671
                     /locus_tag="RD488_001258"
     CDS             32330..32671
                     /locus_tag="RD488_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657343.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDSRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(32664..32855)
                     /locus_tag="RD488_001259"
     CDS             complement(32664..32855)
                     /locus_tag="RD488_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HDT7657344.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSNNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDMTK"
     gene            33065..33712
                     /locus_tag="RD488_001260"
     CDS             33065..33712
                     /locus_tag="RD488_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657345.1"
                     /translation="MVGVVKFLGFTFDGYGTLGEWVGIILIVITIQQTSKYYWYSNSS
                     KIVSRITEGITKKDITVVGKYGFTITLLNEGKSETAIKFCGIIGKYNIFQRFIRKHWY
                     KYIYKYPVVKKLIEKYVDHEISYLNPTDLINQEFQNIGYLEKGLKIPIVNESLVTAMV
                     ANIKNSKKLEKRYKKCKKLKFSFLFLEYNGKEYYQDIYVLRGSNLYKDIKNKISV"
     gene            33972..34316
                     /locus_tag="RD488_001261"
     CDS             33972..34316
                     /locus_tag="RD488_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7657346.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            34321..34602
                     /locus_tag="RD488_001262"
     CDS             34321..34602
                     /locus_tag="RD488_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657347.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            34705..35019
                     /locus_tag="RD488_001263"
     CDS             34705..35019
                     /locus_tag="RD488_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDT7657348.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            34997..36691
                     /locus_tag="RD488_001264"
     CDS             34997..36691
                     /locus_tag="RD488_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7657349.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            36711..37889
                     /locus_tag="RD488_001265"
     CDS             36711..37889
                     /locus_tag="RD488_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7657350.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            37852..38538
                     /locus_tag="RD488_001266"
     CDS             37852..38538
                     /locus_tag="RD488_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDT7657351.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            38538..39698
                     /locus_tag="RD488_001267"
     CDS             38538..39698
                     /locus_tag="RD488_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7657352.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            39708..40583
                     /locus_tag="RD488_001268"
     CDS             39708..40583
                     /locus_tag="RD488_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657353.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            40580..40891
                     /locus_tag="RD488_001269"
     CDS             40580..40891
                     /locus_tag="RD488_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657354.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            40881..41234
                     /locus_tag="RD488_001270"
     CDS             40881..41234
                     /locus_tag="RD488_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7657355.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            41224..41625
                     /locus_tag="RD488_001271"
     CDS             41224..41625
                     /locus_tag="RD488_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657356.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            41618..>42017
                     /locus_tag="RD488_001272"
     CDS             41618..>42017
                     /locus_tag="RD488_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657357.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLN"
BASE COUNT        14563 a         6664 c         8518 g        12272 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 atcgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt cctctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat tatttcttaa ttcaccaatg tattttttgt tcgtcaacat atttttaaca
    21421 ctttgataat ctctaacgat tccatactga gagcctaaat aataaacagt ttttcttaaa
    21481 ctaccactag aaagaaagta gttgaatata tctatcacga taggagcatc atcatttatt
    21541 actaatttct tattttctat agagtagcct aacggagttt tcccgcttac tacttcacct
    21601 tgtgcaattt tatttgccat aacagctttg atgcgttctg aatcaatttg ggcttccaat
    21661 tcagcaaaac tcattacttg tgcaatgaaa gttctgccat acgctgtagt tgtatcataa
    21721 tattgttgag aaacagcatt ccaagaaaca ttgtgttttt ctaaaatttc ttgagtgttt
    21781 aaataatgtc gtagatttct aaaccatcta tctaattttg taaataaaat tagatctatt
    21841 ttattttctt ttacatcttg taatagtttt tgaaattcat cacgatttat tttttgacca
    21901 gaaataccac cgtctacata ttcattaact actttcaaat ccttgtgttg ttcgatatat
    21961 tcatagaggg tttctttttg ttctctaaga ctatctccat gtttggcttg ttgttcagtt
    22021 gatactctca tatataatgc tactcgtttc atgttatctc ctttcgaatg tatgttctta
    22081 tcgttgtaaa agaaaagccc gaaggctttt ttaataataa aaacaattat aaatttaata
    22141 attccttttt cttttcatta aattcttttt gggagataat accctcatct agaagttctt
    22201 tatattttct aatttcatca atttgtgaag ttatctcaac agaagtactc gtttgattag
    22261 atagaatact ttctaattta gcacttagat ggttatattg atcaaatgaa tttttaccaa
    22321 taagtgaatt tatttttgtc tcattgctta tcagatcgta tttgattatt ctattatctt
    22381 taagataaat ttctattcct aatctattaa tggactccca ttcttttcca cctgttccag
    22441 caccaattaa ggctccaata ggccctgcta acgctccgcc tactaaagca cgtgtaattc
    22501 catgatgttt tttgatttgt ccacctaaaa atataggggt aaaggtttgg atttcgtcat
    22561 attttacaat aatttgtgct ctattcataa gtatagattt ttttatcagg aatgctctat
    22621 ctttgtcatt aaaaatgatg tcaccaatta taagatctga atttttttta aagtattcta
    22681 atctattttt ctgaatatct ttagcagata aattcgaaga gtttgaagaa aattttgttt
    22741 taatttgttc tgtcgataaa gattgtacca tttgaacatc tgcgatactt gaagtaaaac
    22801 cagcacgaga aaagcatttt ttacaaacat aatttccatc agaaagtttt attttaccag
    22861 taagagcgcc aattttatct gtacatatta cacaaatttt tgccatttta tattctccat
    22921 ttctatgata tgatttttat aaaaaaagaa tcttagaaat aagtttttta gtccgtgtgc
    22981 cagcacaagc ttttttatat aaaaaccacc taaccgaatt ggccaggtgg ttttgttgtt
    23041 atcacacaat cactctgcca ataacataaa gatcatcata ttcatctgca tagaaatctg
    23101 gatacaagcg atttccattt tcgtcacatt cacaatttaa agatactaat cgtagtcttc
    23161 gattttctac atacattttc tttaaaaatg cttcaccatt tatttctaca gcaccaattt
    23221 gaccattcat aacatttgga gtctgtttaa taaaaactat ctctccattt tcaaaagtag
    23281 gatacatact atttccattt accataaaag caagatcata gtgagaagga atttgagatt
    23341 ctctcattgt taccgtacca aatgggcgct ctttatcata attaggacaa ccatgtcctg
    23401 ctgataataa accgacatat gaaacttcct gtttttcatc ttcatcaaca gcttttccaa
    23461 aattaccttg aataacattc gatctatttt gttcttctaa ttcgttttta gcaaagttat
    23521 agactttttg ctgtcgaggt gacgatagtt gagtataaat aggtaatata tttaaactat
    23581 ttctttggtc tgattgtcca gataaccaag acatttcaac ttgaaaataa tttgcaagta
    23641 aaccaactaa ttgtaatttt ggagaccttt caccattttc atatctggaa agagtagttt
    23701 ttgtagttcc tatttttttt gctaattctt ctaaagttat tcctttttct gctcgtaatt
    23761 ctttgagccg ctgagggaat aatttttcat tcatatttta tcacctccta attttatgaa
    23821 caatacaaat tatagtgtct aaaatacaaa atgtaaacaa aaaagttacc atttggttaa
    23881 aaaaactatt gacaatgtct taaataaaaa gtatgattac tttgtaaccg aacggtaaca
    23941 agaaagaggt gagataaatg ggaaaagctt tcaatcgttt aaaagggtta agggcagaaa
    24001 aaggattaac tcaagtagaa atggcaaaac tattggggat gaatccagat acgtacagaa
    24061 aaaaagaaaa tggtgaacgt gattttactt taagagaagt tgcaacagct caaagagtat
    24121 taggtattga tcctcaatat tatttttttt acaaatttag taaccaaacg gtaacagaac
    24181 gaccagcata gggatgtaat aaatggttag tcgttttaaa tcgagaagta aaaagcctat
    24241 tcgatgaaaa agatatttga agtgtctaaa aaggaaacac gattacgtcc aatgttcttg
    24301 gtgcagatgc tgagttgttt aatcagtaga accaaaagtt gaacaaagta aatcagcttg
    24361 ataatactta atagatagtt gttgagcttc tttctatctt gatcagaaaa tagacacaat
    24421 tcgtctcacc tcgctttcaa gttaattcta ttaagaggtg aaaagaaaac aaactgatgg
    24481 aggtgagatt gtgagtaaca agccaaaaat cactttgaat ggcacaccta atcttcaaag
    24541 attagcagat gaaatggcta gaatacgttc tagacattgg ggagttactg tggtggcaac
    24601 cataattgaa caaaaagaaa agcccacaca gccggcaagc aagtagtggg caccatagaa
    24661 caataatatt atatcacaca ctcgccactt ccgaaaagag gagttgctgc tctcctttca
    24721 agtttgccaa agtccacgtt ttttcatttt ggcaactcct cttcttggag gtggtgacgg
    24781 cgagagacga aggagggatg acatgaagga agaatcaaaa atagggattt tgaatgagaa
    24841 caattacaca agattaatta ttgaaacaga agaagggaaa aaagtagcag aagttacatt
    24901 gaccgatgca actcctgctg acggttatcg tattcgatta actcctaaat atgattaacc
    24961 ttttggtggg tgtggatcgt ttccgtgact atcacggctt tgaatttttc catctctgcc
    25021 atgaataaat agctcagatc cttgattttt agaaatctct ctagcgattt ttactgcttc
    25081 tgattttgta ttagtatgtg cagtcgcttt agaatttcca gcacctttga cattccaacc
    25141 accattggaa ttaggtacaa catgttgatt ttttcccata gttttcacct ccatttctat
    25201 agaaatattt tatcaaatag aaatggagaa attcaataaa cgaaaggaga agtgatatgg
    25261 catatacctt gcaacaagaa catcaaattc tcggtttgat taaacaacgc aggaaacaat
    25321 tacaagatga ccgtgcagcg cttagaaaag ccgatgagct atcagataga caagctgaac
    25381 taattgcttc tgaacttgag gatttgagaa tgctagaaat aaaaaatagg gaggctagat
    25441 tgtgacttta caagagcatc aacgattgat gcaagagtta aatcaggaat atcacaaaga
    25501 tgtgaaacct gagttgctag gtaatcaatg gcgtgaacgc cagaagaagt ggcgagaaat
    25561 aaaaaaagac caactaacga tgagggtcgc taattggtaa taaataaaaa tatatatcag
    25621 gagaattata tcacatgaat aagaaaattg aaaatcttat cgaagaattg aagaaagaat
    25681 gcgacaaaga aaatattggt ctttctttat cattagtaaa tgaggaaaca tttggaatga
    25741 tagctgctgg tccagctaat cttgctgtta tgggtgcttt attgcaagga aaagaatata
    25801 tagaaatcgc tgcaggcaat tgccattgtg aagagtgtaa gaaaataaga gaagtcatta
    25861 atgcggttga tgatgaagtt tcttccacac aacatacttt tgttattaat aacaaggaag
    25921 atttcgctga tgtgatgacc cgtattttca agggggaatt cgaatgatta aaatcaatac
    25981 gctttggatt gcactatttg tctttatgct tgtagtaatc tcaaacgcta atttgtttgt
    26041 aggctgttta tttgcaggaa tgattacttt gctaagcttg ttagaagatt ttacaaagaa
    26101 agaaggcgct aggcatgaac gagttagcaa atcttgacaa ctatttaact gaccctgatt
    26161 atgctaaacc accttatgaa gcgccaattg atgaggagga tgaagatgag taaatctacc
    26221 ttagaaatga gccatcaaga atggctcgaa gaccgcaaaa gaggtattgg tggctcagat
    26281 gttgcaaccg tacttggatt aaacaaatac aaatctcctt atcaattgtg gcttgagaaa
    26341 acgggtcaaa ttgaattgaa agatttagaa agcgaaccag cttattgggg taatgtttta
    26401 gaagaagtgg ttgctaaaga gtttcaggaa cgtacaggca aaaaagtacg cagaagaaac
    26461 caagtatttg aacatccatt acatccattt ttaagagcaa atattgatcg ggaagtagtg
    26521 ggagaaaatg ccattctgga atgtaaaaca gccaatcaat ttctcggaaa agagtgggaa
    26581 ggtgaagagg taccgcttag ctatctctgt caagttcagc attacatgaa cgttttaaac
    26641 aaagactatt gttatatcgc tgttttgatc ggtggacaaa aattcatttg gaagcggatt
    26701 gaacgagatc aagagctgat cgatacaatc actgaacaat tagtagagtt ttgggaaacg
    26761 aacgttcttg gaggtatcga gcctgtaatt gacggaagtg aagcgactgc tgatttctta
    26821 aaagaaaaat atgcagatgt agaagaaaat caaacagctc taccatcacg ttttgatgaa
    26881 cttatcgagc aaaaaagaga actcaaacgg actaagaaag aaattgaatc agctatccgt
    26941 caagtagaca acgagattat cagcgagcta ggtaaacgtg aagccagtat cggtatcact
    27001 caaaaaaaca tcatcagttg gaaatttgtc cgtacgagac gtatgaactc gaagaaacta
    27061 gcagagaaat atccagatgt cgcaaatgat gaagagattt ataacgttac tgaatcaaga
    27121 aggctaaccg aaaaggggat caaataatat ggcaacaaat gaatcgttaa aaaatcaatt
    27181 ggcagaaaag ccacagaaac aagttgcacc aggacagtta gggcttaaag ctctaatgaa
    27241 tacaccaaca atgagaaaga aatttgaaga agtacttcat gacaatgcta atgcttttat
    27301 gtcgaatgtt atgactcttg tatctaatga cagttatctt gcagatagtg aaccgatgtc
    27361 tatcatgagt ggtgcgttaa ctgctgcaac attaaatctt gggctagata agaatttagg
    27421 ttatgcatat ttagttccat tcaatagtaa aaacaagcaa acaggaaaat gggaaaagaa
    27481 agctcaattc atgcttggct ataaaggata tatccaatta gcccaacgat caggtaaata
    27541 caaagcatta aatgtgatcg aagtttacga aggagaacta aaaagctgga accgactgac
    27601 agaagagttt gagtttgatc caaatggtag aacgtctgat gaagtcattg gatatgttgg
    27661 ctatttcgag ttactgaatg gattcaaaaa aactgtctat tggaccaaac aagaaatcga
    27721 agctcatcgg attgctaaca ataaagatcg cgataagaca aagttaagtg gtgtgtgggc
    27781 atctgattac aatgcaatgg cacgaaaaac tgttttgaga aatcttcttt ctaaatgggg
    27841 aatcttgtcc atcgaaatgc aagaagccac cacatcggat gagagagtcc aaagggttca
    27901 agaagacggc agcattattg ctgaaacaga agttgaagaa gatattcctg aaagaaaaga
    27961 agcagaggtt atatctgaag aaaatgaaga tgtacaaact ggattatttg atgcatctaa
    28021 tccgccgtta aacaaataat gagggagctt tctcccttgc ttttctagag gagaaatacg
    28081 aatgaacaca ggatatgtca aattacatcg aaaagtgatg aattcattcg tttggaccaa
    28141 tccttatatg tataaattat ggagcttgtg tttgatgaaa gcgagtcatg agaatcgcaa
    28201 gatacttttt aatggaaaag agatacaagt gaacagcgga gaattcgtca cagggcgcga
    28261 tgctatcaca tctgagatga acgaaggcgt gaaacgtgaa catcaagtga acagcggttc
    28321 tgtatggaga tggctaaaac aatttgaaaa aaacggaatg ttgaacatca aatcaactac
    28381 gaaatacagc gttatatcaa taaaaaactg gtctttgtac caaagcagtg aacaacaaat
    28441 gaacatcaaa cgcacaacaa gtgaacaaca agtgcacaca aacaagaatg aaaagaatta
    28501 taagaatgaa aagaataata aaacatcatc gtcgcaacca cgcaaaaagc gtgtttacga
    28561 caccgactca gtttactaca ttctcgcgga ggagttattc aaacagattt gtcagaatca
    28621 ggaaatcaaa aagccgaatc tgcaaagttg ggcagataac attcggaaaa tgatcgagat
    28681 cgacaagcgg accgaaaacc aggtacgggg aatgattgaa tggagtcagc acaatgtgtt
    28741 ttgggcatcg aatattttat ctgctaaaaa attgcgagaa aaatacgaca caatggcagc
    28801 gcaagcaaat cgtgattata aaacaaaaca aactaaaacg cttgaatacg agaaatttag
    28861 cacagatgag ttgcctattt gagaggaggc gtaggcatgg aaactgttgg ggaaatcatg
    28921 gaaaagctga tacagaaagt gcttgtccaa cgtggcgaat gtcctgaatg cggacagcct
    28981 ttgtatggat ggcgtacgaa gaaccctgat ggctcagaac gttgtaagcc aacctgtatg
    29041 caatgtgggt ataaagcatt gcgagttcag gaagacttac aaacagaacg aatttacaac
    29101 gagagcctga aagcaagagc aatcaatttt ttcaaaggtg gttctgttgt gcctaatcaa
    29161 gcgttgtttg attgcacatt gcagaattat caaattgtcg atcaagaaac aagacaagcg
    29221 gttgaagtaa ccaaacgctt tgttaattca gtcttgttag gaaatccaag tcaccttgtt
    29281 ttaactggaa aacaaggaac aggtaaaagt cacctagcga tggcagcggc ttgggaagtc
    29341 ttgaagcgat caaactacga taaaaaaatc ttatttatcg ggttacagga aatgctggat
    29401 caaatcaaat tttcgtacaa caatcctgaa ctcagaaaaa cgattgaggg atcgttgatt
    29461 gcagatatca aaacagcgga tttagtcatc attgatgata tcggttcaga actaggaaaa
    29521 gatgcatcag atagtcgagc gtttggcata aacacgctaa attcgttctt ggatgcacga
    29581 cagaacctag caacgattat cacaacgaac ttgcttggtg aagaactgaa aaaagcttac
    29641 ggtacgagaa caatatcaag aatgtttgtc aactctgatg gatttacgat ggtattttct
    29701 caaacagcag acaagcgcat aaaaccagtg aaaggtagta tcgcatgaat aaataccgta
    29761 ataaaaaaac tgttcatcga ggtatcaagt ttgattctat cgcggaagca gagtattacg
    29821 atctagcctt gtggcaagct gaagcaaatg gctggaaagt aaaacttcag gaaagatttg
    29881 agctgatgcc gaaatttgaa ctagacggaa agaagtatcg caagatcgag tatattcccg
    29941 acttcacatt ttataaaaac ggcaaacttg tcaaagtcgt agatgtcaaa ggaatgcaga
    30001 caaaagactt taagatcaag gcaaagttgt tctgtcatca atatcaagcg ccgttgatat
    30061 tagctaaaaa atatcggaat acgttcaagg aagagcgttt ttaacgaggt ggtccatcat
    30121 gacaacagaa gaagtgattc aaatgcgtat tcgaaacatt cagcgtgaaa ttgacgatct
    30181 agaacgaaca aaggcagtga tggtcaatga aacggcgaga aaggcaatcg atttgcacat
    30241 agagaactta agaagggaaa ttcgtagatt ggaggaatga gcgtggataa gaaagcgaca
    30301 atgaaacgaa ttgctgaatt aaccaagtca gaatcttggc aggaagacaa agaaatagtt
    30361 gcagaagtcc aaaagctcgg taaatcaatg tggactgaaa agcctaaacg gaaaacgccg
    30421 agaaaaattg caatctggca tggtgatcga attctagtaa caggtacagc tgaacagtta
    30481 tctgaaatta ctggattaag caaaaacatt atctgggata gagctaggag cttatggatt
    30541 gattcaaaag gacgacagtt taggtatgtg gaggagagat aatggatctc attacacaat
    30601 acagtgacat catcctcaag aaaatcatga tgaagattca gaaagacaaa aaatcaaaag
    30661 aacgagctga attagttaag ttagaaatgg ctgaaacagg agcaggagtg cgaagtagca
    30721 ggcattggaa agcagcagca aacattgaat tttattacaa cgaaattcaa aaagggttcg
    30781 atcagatgcg tgagctggat cggcaaacaa attggagcaa gaaacttcat caagatcgtt
    30841 tcaaatttgt agagaagtat aaagaaatat tagaagagta tttgaggagg acagcaaatg
    30901 ataaaaaaac tcgttcaatt cagcatggat ttatatgata tcgaatcagg agcaacacta
    30961 tctgtggaat cggaccatct aatcataaat tttggtggaa agcgccagat tattttgtgg
    31021 gtagttgatg atgtactgtt tccagaaatt gttcatgatt tcgaagaatc aaaagcggtt
    31081 gagtttgaaa tagtgaaaaa agtaatggaa ttgattgaaa aatacgagga ggacagcgaa
    31141 tgataccgaa gtttagagcg tgggatagag aaaaagacag aatgaaggca gtagctttgg
    31201 ttgaatttgc tgaggcgtat aaatcaggag aactcatttc acgtacaaaa taaaaaaagt
    31261 cggattcctc cgactatgaa taatatttcc gacataagta ttatatcata attgggggaa
    31321 tcagaggatg gtacttttcg atgtaaagaa atatgagaca ccaagcgcga aagatgttga
    31381 tatggaacgc acaaaacata atgtcgctgt gtttctttca gcatatctat cagctagatg
    31441 tagagtaggg caacctcgag aaccaaaagt gacagcatct tattccttgg ttccaccttc
    31501 tacagctgat catatatttg aagcagaaag aatgctgatc gataaagaag aagcacagga
    31561 agaatttgag tatctgcata aattgtttgt tcgaggctat tcagcgatac agcatccgca
    31621 taagcctgat gtgactgaaa ggcgcaagaa gatattctat gatcgttata tcaatggtct
    31681 gcccatttat gtaactgctc aaaggaataa tactagcgaa gaatcggtta aagtagaatc
    31741 aaacagaatt atcatccaat ttgcttcatc gttagaactg gttgctttca agtagccagt
    31801 ttttacactt tttataccct tttattacca atttggtttc cattttatac cttttttata
    31861 ccaatcactt acctattcaa cgttgtatta tgatagtgtc gaaagattag gaaacaggat
    31921 cgacaaaata aaatgtaagg gaggaaatct ccctcatcgt ttaattaagc ttcgataggc
    31981 agcagcggaa atattaagaa taaggatgtg aatttcaact ccttctaaat tgttcttatt
    32041 atctatcatc cgttgctgtc tattaattta tgtattggag ggtatataaa atgaagatcg
    32101 cttccgaaaa aattgatcaa ctaacaattt tagtaaacca aagaatcgaa gatattatca
    32161 aagaattcga aggtgaaaag attaagaaca taaagcttac tttaatggat cataagttcg
    32221 aattaaattc gacaaaaagg aagatcgttg agcttataga agaagaaata gctctccaga
    32281 tcaatgagca acaattagct aattaattta tgtattggag gggaaatgaa tggaagtcga
    32341 acaaataaag tatcaaggta tggatcggga acggttgatt gatattattg agcaacaacg
    32401 tttagaattg atccaaaaag aagctgtatg taaagagtac aaaaaacatt tggaacaagt
    32461 aattgagtat cattcagtag aaaagtacag atcagtggtg caaaaaaata gagcaacgag
    32521 tcctgattct cgtcaagatg tatcgattag tatcaagacg ccagtattta attctgttaa
    32581 atcagaaaag ctagaaagta tctcaactgc tttggtagaa aaagcagctg aaatgaactc
    32641 cctagcaaat gaagttagtc gtcttattta gtcatatcga taacttgaga gtctttggtg
    32701 attccgtttt ttatagaatt aatggtttgt tcagcggaat atttagtcaa gtatgtttcg
    32761 ctagttgcta ctacttcatt gttattggac ttaataacga agtaatattg gccattagtt
    32821 gcttctctta taacaaagta caaatttttc accacctata atttatttca gcggaccact
    32881 cgctgataat taaaattata agctatgtat aaaatttcac aatatcaatt tgtcgctgtg
    32941 gcggaaaggg tagacgcaat aaaggatgaa tgggaaaagt caatgagtaa ttatctgaaa
    33001 tttacaagtc ccctgtttag ttatctaaga ttatttgata atattatttc tgaggtgata
    33061 gaaaatggtg ggcgtagtta aatttcttgg gtttacattt gatggatatg gtacgttagg
    33121 cgaatgggta ggtattattt tgatagtgat tacaattcaa caaacatcaa agtactactg
    33181 gtattctaat agttctaaaa ttgtatcaag aataactgaa ggaataacca aaaaagatat
    33241 tactgtcgtc ggtaaatatg ggtttactat aactttatta aatgaaggga aatctgaaac
    33301 cgcaataaag ttttgcggga ttataggtaa atataacatt ttccaacgtt ttatcagaaa
    33361 gcattggtac aaatatattt acaaataccc tgtagttaaa aagcttattg aaaaatatgt
    33421 ggaccacgaa atatcttatc tcaatccaac agaccttatt aatcaagaat tccagaatat
    33481 tggatactta gaaaaaggtc taaaaatacc aattgtaaat gaaagtttag ttactgcaat
    33541 ggtagctaac ataaagaaca gcaagaaatt agaaaagaga tataaaaaat gtaaaaaatt
    33601 gaaattttcc tttttattct tagaatataa tggcaaagaa tattatcaag atatttatgt
    33661 tttgcgaggc tcgaacttat ataaagacat taaaaataag atttcagtat gagatttttt
    33721 aaaattcgta gatcactctt tgagtggtct ttttattttg cgtaaaggag gcacgacgat
    33781 gtatagacca caatacttag aacagaagca tgaagtaatc actgtgcaaa acggtaacgg
    33841 tgagatagta cgaaagtata gaagaccaat aaagagcgat acatataaac ggaaggaaag
    33901 caatgaagtt attccattgt atggcaaaag aatagctaag tattaaataa gattgcgaaa
    33961 ggagatggga catgaccgag gaattctata gatggttatt acagttgata agagaagatc
    34021 gtttggttaa gttctatcag tctcctaaat ggcgcaggct tagagagaaa gcgatgaaac
    34081 gagatcacta tgaatgccaa gagtgtagaa gactaggtaa gtatcataga gtagagaacg
    34141 ttcatcatat aaaggaagtc aaggatagac ctgacttagc tttagattta gataatctta
    34201 tttgtttatg tgttgaacat cataatgaag ttcatggcag atatcttaca gcgttagata
    34261 aacaagagaa gaagatagaa agcttcgcta acttcgatgc aagtgaaagg tggtaagtgc
    34321 atgatcatca atgacaatgg cagagagtat gatacagaaa agattgaaga gtattcatct
    34381 tatactcagg gattaattaa acgtttgata tacgttcgct atgtaggtat tagggatctg
    34441 ttatcagata actgttgtag taaatacaaa gtgaatcaag taagagaagc gttgaataaa
    34501 gataataacg tcgaaagaat aaaaaatgtt tttggatata gtattgaaga gattaattat
    34561 tacattgact tcgctgaagc tttcattccg atggtgagat aaccccccct taaaataaat
    34621 cgcaaatttt ttgggggtga tgaaacggag ggggctgtca ggaaaagaga ttttttcgaa
    34681 ctttatcatg aaaggagggc taaaatgttt aaaaacgaat tgtctcaaaa tcgctacaga
    34741 gaaaaattac gccgctcttt aataagccaa ttggaaagtc agaaaacaaa tattgagcca
    34801 ttcttagata atgttgatcg ttatatcagt ttatgggaaa cggcgatatc actggaagaa
    34861 gatatatccg agaacggcat tagactggag aatggtaaaa agaatgaatc agtagcgttg
    34921 cttgtttctg tcaacaaaca aatgggattg atgttggata aacttgccat tactcctgaa
    34981 ttggtaggtg aagcaaatga atcaattcct gagttataag catattgaaa attggttcaa
    35041 agctatagaa gaaggcacta tcaaggtatg caaagagcaa ttattgctaa aaaattatct
    35101 agaagaaaga gtctttacta gagaagatat ttacttcgat aagcagatgg tagaggattc
    35161 aatcaatata ccagcacaat actttccatt cgaattaatt ccgtgggaaa aatttctaca
    35221 atgttttatt tatggtgttc gatggaaaaa agataaaaca ctagtgttca atagatatct
    35281 ttcattaatg ggacgtggta atggtaaaac tggttttgct tcttggaaca acttctttct
    35341 actaaccgct aaacacggta ttaaaaatta tgatattgat atctatgcca ataatgaaag
    35401 ccaagcaaag actagttttg atgatgtatt taaagtaatt aaagatcatc ctgatttaga
    35461 taaaaaagta tttaaagcta cgaaggaagt tattcaaaat atcgctacaa acagcaaact
    35521 tcgttataac acggcaaatg ctagaacaaa agatgggaag cgaccaggtg caaaccgctt
    35581 tgatgaaatt cacgaaaatg aagattattc aatgataaat gtggctactt ctggtggtgg
    35641 taaaattcga gattatagag aattttatga tacaactaat ggtcatgttc gtggtggtcc
    35701 gcttgatgac attatagaag aatcaaaaat gattctttct ggagaacttg gaattgacaa
    35761 ggatggagca gaattttcta gtttgtttcc atttatttgt cgcttggata acgataatga
    35821 agttgatgat cccgacatgt gggaaaaagc ttgtccaact attaattaca atgcagattt
    35881 aaaacggaaa atgtttcaag aatactctca aatgcaacgt aatgctggtt taagacttac
    35941 gttcatgacc aaacgaatga acagacctat ggaagataca cgatttgctg ttgcttcata
    36001 tgatgatgtt ctgcatacga aagaaaaaga atttcctgaa aaaatggatg aagtgatagg
    36061 aacagtcgat tttgctgata gacgagattt tgccagcgtt gggttgctag gaaaatacga
    36121 taaagatgtt tattttacac aacatacttt tatccacgaa tcagcccttc gattacaaaa
    36181 catcaaacga gaggttatag atatttctat agatcaagga aaatcacaga tcgttcatgg
    36241 aaaaaatata gaagctgatt atattgtagg ttggtttctt gaaatgagta ataaatatta
    36301 tattaaaaaa atcgctatgg atatgtaccg tgcaaaaata ttgaagcccg ctttagaaga
    36361 agcaggtttt actgtggaaa ttgttcgaag cggatctgtt acacatggta tgttaaaaga
    36421 tctggttgat gaccttttta ttaatcaacg tttatttttt ggtgacgatg cgattatgcg
    36481 ttggtattgc atgaatgtat atgaagagca tatttctaat ggaaatatac gctatgaaaa
    36541 aatagaacct gaaactagaa aaacggatgg ctttttttca ttccttcatg gtttgaattt
    36601 tttagatgat atttatgatt ctgctcctgt aacagtcaca aatagctcag tagaaaatac
    36661 aggaactgga tttactcctc tagtattcta acttgaaagg aggtgagaaa gtggggattt
    36721 ttcaaaaggc ggtaggatac ttcacaaaaa aagcaacggt tcctttagaa gaatactttt
    36781 gtaaattgca agttgatttt gtgtatcgaa aatttgcgat tgaaacttgt attgatttga
    36841 ttgcaaatgc gatgagtaaa gcggaattca agtcatatga agatggaaaa aataaaaaga
    36901 atgatcttta ctataggctg aatgtagctc ctaataagaa aaataatgca acagaattta
    36961 gaaaaaaact gatcaggaga ttaatattct acaatgaagt attgatcgtt tctccgtcta
    37021 ataattctag cgaaatattt attgcggata gttgggatgt cacagaatat gcattgaaag
    37081 atgatgtgtt ttctcaagtg caaattaaca acatagtcct tgatagagaa tttctagaaa
    37141 gtgatgttat ctatataaaa tacgcagatc aacaaattag gcaactagtc gatgcgtatt
    37201 atcaagcgta tgggaaactc atttctagtg ccatgaatgt ttacaagcgc tctaacgctc
    37261 gtagatacgt actgaaaggg aatttattcc gaccgcaaga caatacaaca caagatcaaa
    37321 tcaataaaat gatgacatca caatttaagg cttttatgga agctgataat gcaggtgcgg
    37381 tatttcaatt acaaaatgag tacacattag aagatttcag cggaaacttc caaagcaatt
    37441 caagagatat aaaaaactta atagacgaca tctttgagat gacagcagca gcgtttcacg
    37501 ttccgaaaaa cctactaaag ggagacatga gtgggttatc ggatcaagtg gacgcttttt
    37561 taatgttcga aatcataccg attgctgaac ttattcagga tgcgtttaac gctagtctct
    37621 atgaagtaga agaatacttg tcagggaatt ttgtacgtgt ggatacaact atgatcaaga
    37681 ttactagctt caaagatttg gttgacgcta ttgatgtagg cattagaaat ggagtattta
    37741 caatcaacga aggaagagag cgcgttggaa atgatcgctc tgataaggcg atggcagatg
    37801 aaatatttat aactaaaaac aatcaacaag tatcgaaagg aggtgaggcg aatgacgaca
    37861 atgaaaacat ttctagcagt aaagaatgaa ggcgcagtac cgcaaatttt tattcaggga
    37921 tttattggtt ctagttggtt ctttgaaggg aatactgaca agggaatcaa aaatattttg
    37981 gatagtctag gtgatcaaga agaaattgaa gtagtaatta attcaaacgg tggagacgta
    38041 tttcaaggga ttgctattgg gaacttactt aagtcaaata aagcaaaagt taacgttgtg
    38101 attaacggct tagccgctag tgctgcttca attatcgcaa tggctggcga tactataaaa
    38161 atctacaaca atgcacaatt gatgattcac cgcgcttcca catacggaga aggaaatgtc
    38221 gatgacttcc gtacgattgc tgaccaactg gaatcaattg ataaatcggt aaaggcttca
    38281 tataaaacac gattcaatgg cacagatgaa gcattgcaag aacttcttga aaaagaatcg
    38341 tttatggatg cagaaacagc tttgagttat ggattggtcg atgaaattat cgatgcagaa
    38401 aatagctcag gtactgaagc taaaaaagaa caaagcgttg aagaaatttt gaatgacgtt
    38461 aaagaaaaaa gagcagaaaa aattgctgca tttacagcag cattaaataa aacatttgga
    38521 caaggagatg taaaataatg acagttaaaa atttaaaagg tgtaacagct gcaagcgacc
    38581 aattgatgaa agcttttaaa gatggtaacg aagaatcttt tagcgcagct atggtaagct
    38641 tatctaagga aattcaggat aaaattttag aagaagcaac agcaaaaaat caagatcaat
    38701 tagtattaat gaaccgtggt cagcgtgtat taactacaca agaaacaaaa ttctataacg
    38761 aagtagtgaa aaacgaaggt tttgcagggg tcgaagaatt agtgccagct actgtatttg
    38821 aacgtgtatt tgaagattta gaacaatctc atccactatt gcaaaaaatt acttttgtta
    38881 acacaactgg tgtaacagaa tggattgtgt cacgtggagt caatccagca tggtggggta
    38941 aactttgcga agctgttaaa aaagttttag ataatggctt tgatgtaatt aacatgaagc
    39001 agttcaagct atcaggttat attcctgtat gtaaggcaat gcttgattta ggtccagtat
    39061 ggttagatcg ttatgtccgt actgttttag tagaatcatt gagaattgca ttagaacaag
    39121 caattgttga tggtactggt aaagatatgc cagtcggaat gatgcgtgac atgagcaaac
    39181 aaactagcgg agaatatgct gaaaaaaaag cagaacctat tacagcttta gatgctgtaa
    39241 ctatgggcgg tttgatggcg cgactatcaa aattcaatat cgaaggtgtg aatgatccga
    39301 tttatcgtaa tgtgaatcct tctgatgtgg tcctaattgt gaatccaact gattactggt
    39361 ctaaagtatt cccagctaag actgtactaa ctgctaatgg agaatacgta caagtattgc
    39421 cagtaccagt ttcagatttg cagtcaacgg ctgtgccaga aggaaaagca gttattgggg
    39481 tagcctcaga ttacttcatg ggtgtaggat ctacactaaa aattgaagct tcagatgaat
    39541 accattttgt tgaagacgaa cgcatttatc tagctaaaca atatgcaaac ggtcaaccta
    39601 aacgtaacga tagtttcatt gtattagata ttagcgcttt gggaactact actacaacta
    39661 caaaaccaac aaccacaaca actacaacac aagcgtaggt gatcagaatg aagtatattc
    39721 tttgtcagcc ggcaatcaat cggtttaaat gggagcttga agtttgttta actaatctga
    39781 agaaactagg aatcaaagat atcgtattgc ttttcagcag acacgatgat cagattccta
    39841 ttttttttga gaaggaatat ggtgttgaag ttcatgtgta cgatgatctg cgggacgaca
    39901 aagagtatat tccttcgatt aaaccatatt tatggtggaa atatttagaa gaagatcatt
    39961 cgcgtgagga cgaccgatat ttctatatcg attcggatgt cattttcaat aaaagaatta
    40021 atttgcgcaa attgccttct aaagatgatg tttggtattg tagcgactgc tgtagttatc
    40081 taagtcttga ttatattaga agctgtgaaa acggagaaaa tattctaaaa gatatggcaa
    40141 acattgtaaa tgttacagta gaatctttgg aaactataaa cactaattca ggaggcgcac
    40201 agtgggttat taaccgccct aaagcgaatt attggaaaaa ggtttatctg gattctaatc
    40261 ggctatatcg ctaccttaga gggcaaaaaa caaatataca aatctggaca gccgagatgt
    40321 gggcacagct ttggaacatg atgtatttca atattggtcc taaagttcac gaggaattag
    40381 acttttgttt tgctactgat ccaatagaaa aagttaaaga agtaaaaatc ttacacaatg
    40441 ctggagtaac aacaaacgat gaagatttat ttttcaaagg gagatacgtg acttctacgc
    40501 cttttgatga agatttatca tttgtaaaca agaaaaaatg ctcttacgca tatgttaaag
    40561 caattaaggc ggtggttaga tgacgcctga acaagtgact gaagaattgc taatagctgt
    40621 gaaggataat atttacgtta cctggaacga agaagatgag tcaattaaaa agatgatagc
    40681 taaaaatgct gtttatcttc aaagtaaagt gagtacaaca ctttcttttt ctcctgaaag
    40741 cttagaatac ggattgctaa tcgaaagatg tagatacgac tggaatcgtg ctttagatga
    40801 gtttgaacaa aatttcgcta gtgagttatt aggtttcatt caacattatg cgctacaaga
    40861 atatattgca ggtgatgtga atggcgaata atcgtagact cgaagaaaca ttcaacgatg
    40921 gttggttaaa gattttgacg caaactacca aaagaaatga actaggaaaa aagattggtg
    40981 tagaagatac agaaatcact tctttaaaat ttagaaatct ttccatgaga gatagtgata
    41041 taacagctat ggatgcgatg ggatcgaaat taactaagaa agtaaagact ccatttcatc
    41101 caatcgccaa gaaatttaat aaagatcaat attttatcgt aatcgatagt atgcgttaca
    41161 acgttatcta tgccgattac gataattttt atatctattt ttatcttgaa agtgtgggtg
    41221 aatatggtga ttgataattc taaagaaaaa gaacgtttaa ataagcaaat ttctgctatc
    41281 aaaacttcct tagaagagca ttttggcctc aaactctttc aagactccgt aggcgaggat
    41341 gagctacctg atgattttaa ttacttcatt ctcgaaacag gagaaataga aatgatcact
    41401 gagccaaaat atagcgtggg tcaaaatcta tatctaactt tctattcaga aaatagagaa
    41461 gatttaacag gagattcact agatattatt tcattgattc aaaatcgttc gattcgtttt
    41521 cagagaatgg atcccaatca tttaaaacta gagaaccaag atcgctatat cgatcaattg
    41581 gtatttacgt ttagacgatt attgaagagt gattgtcatg gctaaaaata gttgggagct
    41641 aaaaataaat ggacatgatg aacttcttgt gcggatggaa cgctattcaa gcgagagcga
    41701 acgactgatt aacgaagcat tgaaatcaaa aggttcggct attgcagtgg ataggattac
    41761 agaaaaaatt cctgtttctg aagcagattt aagaagaggg caccaacacg caaaaaatag
    41821 tcgtccactt aagactcaat acattaattt gggtttcatc attagaccta caagaaaatt
    41881 tgagtattta aaatatcctg atttggggat aggtacttct aaaagaaatc agccggacga
    41941 atttatgaga agaggattag gtcttgcact tgatccaatt acagaacttc tgattcgtca
    42001 attcgataaa ttaaata
//
LOCUS       DAPBBR010000022        42013 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPBBR010000022 DAPBBR010000000
VERSION     DAPBBR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.022"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            344..793
                     /locus_tag="RD488_001273"
     CDS             344..793
                     /locus_tag="RD488_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7657358.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            850..2268
                     /locus_tag="RD488_001274"
     CDS             850..2268
                     /locus_tag="RD488_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7657359.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            2268..3128
                     /locus_tag="RD488_001275"
     CDS             2268..3128
                     /locus_tag="RD488_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDT7657360.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            3302..4075
                     /locus_tag="RD488_001276"
     CDS             3302..4075
                     /locus_tag="RD488_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7657361.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            4222..4587
                     /locus_tag="RD488_001277"
     CDS             4222..4587
                     /locus_tag="RD488_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HDT7657362.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(4735..5943)
                     /locus_tag="RD488_001278"
     CDS             complement(4735..5943)
                     /locus_tag="RD488_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7657363.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(5962..6240)
                     /locus_tag="RD488_001279"
     CDS             complement(5962..6240)
                     /locus_tag="RD488_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657364.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            6394..7089
                     /locus_tag="RD488_001280"
     CDS             6394..7089
                     /locus_tag="RD488_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7657365.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(7531..8328)
                     /locus_tag="RD488_001281"
     CDS             complement(7531..8328)
                     /locus_tag="RD488_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDT7657366.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(8325..9509)
                     /locus_tag="RD488_001282"
     CDS             complement(8325..9509)
                     /locus_tag="RD488_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7657367.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(9534..10781)
                     /locus_tag="RD488_001283"
     CDS             complement(9534..10781)
                     /locus_tag="RD488_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7657368.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            10996..12741
                     /gene="dnaX"
                     /locus_tag="RD488_001284"
     CDS             10996..12741
                     /gene="dnaX"
                     /locus_tag="RD488_001284"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDT7657369.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            12761..13075
                     /locus_tag="RD488_001285"
     CDS             12761..13075
                     /locus_tag="RD488_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDT7657370.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            13100..13696
                     /gene="recR"
                     /locus_tag="RD488_001286"
     CDS             13100..13696
                     /gene="recR"
                     /locus_tag="RD488_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDT7657371.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            13760..14404
                     /locus_tag="RD488_001287"
     CDS             13760..14404
                     /locus_tag="RD488_001287"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDT7657372.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            14419..14748
                     /locus_tag="RD488_001288"
     CDS             14419..14748
                     /locus_tag="RD488_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDT7657373.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            14762..15700
                     /gene="holB"
                     /locus_tag="RD488_001289"
     CDS             14762..15700
                     /gene="holB"
                     /locus_tag="RD488_001289"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDT7657374.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            15736..16560
                     /locus_tag="RD488_001290"
     CDS             15736..16560
                     /locus_tag="RD488_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDT7657375.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            16553..16900
                     /locus_tag="RD488_001291"
     CDS             16553..16900
                     /locus_tag="RD488_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDT7657376.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            16969..17841
                     /gene="rsmI"
                     /locus_tag="RD488_001292"
     CDS             16969..17841
                     /gene="rsmI"
                     /locus_tag="RD488_001292"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDT7657377.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            17950..19071
                     /gene="dinB"
                     /locus_tag="RD488_001293"
     CDS             17950..19071
                     /gene="dinB"
                     /locus_tag="RD488_001293"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDT7657378.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(19125..19727)
                     /gene="nrdG"
                     /locus_tag="RD488_001294"
     CDS             complement(19125..19727)
                     /gene="nrdG"
                     /locus_tag="RD488_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDT7657379.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(20042..22231)
                     /gene="nrdD"
                     /locus_tag="RD488_001295"
     CDS             complement(20042..22231)
                     /gene="nrdD"
                     /locus_tag="RD488_001295"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDT7657380.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            22530..23324
                     /locus_tag="RD488_001296"
     CDS             22530..23324
                     /locus_tag="RD488_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657381.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            23314..25356
                     /locus_tag="RD488_001297"
     CDS             23314..25356
                     /locus_tag="RD488_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657382.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            25637..25786
                     /locus_tag="RD488_001298"
     CDS             25637..25786
                     /locus_tag="RD488_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDT7657383.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            25797..27311
                     /gene="dltA"
                     /locus_tag="RD488_001299"
     CDS             25797..27311
                     /gene="dltA"
                     /locus_tag="RD488_001299"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDT7657384.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            27308..28513
                     /gene="dltB"
                     /locus_tag="RD488_001300"
     CDS             27308..28513
                     /gene="dltB"
                     /locus_tag="RD488_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDT7657385.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            28558..28791
                     /gene="dltC"
                     /locus_tag="RD488_001301"
     CDS             28558..28791
                     /gene="dltC"
                     /locus_tag="RD488_001301"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDT7657386.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            28794..30062
                     /gene="dltD"
                     /locus_tag="RD488_001302"
     CDS             28794..30062
                     /gene="dltD"
                     /locus_tag="RD488_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDT7657387.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            30203..31285
                     /locus_tag="RD488_001303"
     CDS             30203..31285
                     /locus_tag="RD488_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDT7657388.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            31285..32088
                     /locus_tag="RD488_001304"
     CDS             31285..32088
                     /locus_tag="RD488_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7657389.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            32158..32898
                     /locus_tag="RD488_001305"
     CDS             32158..32898
                     /locus_tag="RD488_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7657390.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            32909..33913
                     /locus_tag="RD488_001306"
     CDS             32909..33913
                     /locus_tag="RD488_001306"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDT7657391.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(33958..35802)
                     /locus_tag="RD488_001307"
     CDS             complement(33958..35802)
                     /locus_tag="RD488_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657392.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            36014..36532
                     /locus_tag="RD488_001308"
     CDS             36014..36532
                     /locus_tag="RD488_001308"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7657393.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            36660..37343
                     /locus_tag="RD488_001309"
     CDS             36660..37343
                     /locus_tag="RD488_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDT7657394.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            37652..37725
                     /locus_tag="RD488_001310"
     tRNA            37652..37725
                     /locus_tag="RD488_001310"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37686..37688,aa:Arg,seq:tct)
     gene            37884..38243
                     /locus_tag="RD488_001311"
     CDS             37884..38243
                     /locus_tag="RD488_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HDT7657395.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            38366..39997
                     /locus_tag="RD488_001312"
     CDS             38366..39997
                     /locus_tag="RD488_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HDT7657396.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(40059..40700)
                     /locus_tag="RD488_001313"
     CDS             complement(40059..40700)
                     /locus_tag="RD488_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7657397.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    40886..40962
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            40982..41290
                     /gene="rplU"
                     /locus_tag="RD488_001314"
     CDS             40982..41290
                     /gene="rplU"
                     /locus_tag="RD488_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDT7657398.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            41317..41661
                     /locus_tag="RD488_001315"
     CDS             41317..41661
                     /locus_tag="RD488_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDT7657399.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            41674..41967
                     /gene="rpmA"
                     /locus_tag="RD488_001316"
     CDS             41674..41967
                     /gene="rpmA"
                     /locus_tag="RD488_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDT7657400.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT        13381 a         7295 c         8691 g        12646 t
ORIGIN      
        1 tcgtaggatc ataatgcaca aaacaatgaa aaactagtat atagttttaa ttatccactt
       61 gataaaaaca ccttatatta acgaaatgaa gaggggttat ttcgaagtaa aaaaccattt
      121 acctaaaatt agaagctaag ctttcctttc aaggaaggct ttttgttttg ttatagactt
      181 gcgattgttt gtgagctaga tcgttcattt taatgactta tacacgcgga tgatgggtct
      241 ttttcctctg ttcattcata atattgaacg gtacagctag cgatgctata ctgacctcag
      301 ttccaagaaa acgttaacat tttttgtggg ggagaggttt tttatgaggt ttgatcaatt
      361 gatcgcagaa gaactgattg ttttcgatcc atcgatagat tcaaaaggat cattatttga
      421 gcgaataggg gatgtgttga aaaaaacaaa taaggtaaga aatgttcaaa aagtcgttaa
      481 ggcactattc aaacgagagg aggagatctc cacaggaata gaagatggat ttgggattcc
      541 ccatgcaaaa agcaaatatg tgacaaaacc agcactgtgt ttttttcata cagccaaatt
      601 aacggactat agcgggatag atgaaatgcc aattgaatat atttttgcca tcgtagttcc
      661 tgaaaaatca gcagatatgc atctagagat tctcagcaca ctctccagac gattgatgaa
      721 tgcagatttt agaaagggaa taaaagaagc cactacgcca gcagatatca tcagacagat
      781 tagtcaagaa tgaaaatagt agagtctttg tccgagtatc gatagtgaag aaaaaggagg
      841 aaaataatca tgaaaatcgt tggtgtaact gcttgcccga ctggaattgc tcatacttat
      901 atgtcggcag aaaaattaga agtaacagca agaaatctaa accatcaagc aaaattcgaa
      961 acacaaggtg taaaaacaga aaatcagtta tctgaacaag aaatcaaaga ggcagatgca
     1021 atcattcttg cagtagataa agaaatcgaa ttggaccgat ttgccgggaa aaaagtaaag
     1081 cgtgtctcta caagccgagc aatcaaagaa ccgcaagtag taatagacga agcattgaga
     1141 gatattggcg tattcgttgt gtcaaatgaa aaagaaccag ctgcaaatga gaaaaagccg
     1201 acaatctata atcatttcat gaatggtgtg aattacatgc ttccatttgt gatcgcaggc
     1261 ggaatcatca tcgcactgag ttttgccttt gggattacag cggctgatcc caactcagca
     1321 gactataatg tgttagcagc tgcattttca aggatcggag gagatacagc gtttgccatg
     1381 atggttcctg cgttaggcgc ggggattgct acatcgattg ctggaaaagc aggttttgcc
     1441 ccaggaattg ttgccggatt actggcctct acaggtggtt caggttttct tggcggaatg
     1501 attggtggcg tgctagcagg gtatatctgt gattttctgg caaataaaat tagcgtaaaa
     1561 aaagaatttt ctgctattta tcagctgatt gtcgtcccct ttttatcgat cttaattatt
     1621 gggcttttga tggtatttgt gattgaacaa ccgatcacat gggtgttgga tgctttgaca
     1681 aattggctga atagcttggg aaatacatcc gggctattgt tcggattact tatcgggatc
     1741 atgatggcag ctgatatggg tgggccgatc aataaatcga cttcgacttt ctcgatcggt
     1801 ttgatgtcag ctggagtaaa tgcaccgatt gctgcttgta tggctgcagg aatgacacct
     1861 cccctaggta ttgctttagc cactttatta ttcaaacata aatttaccaa agaagaacgg
     1921 acttcaggtc aatcatgctg gattttaggc gcttcgtata ttacagaagg tgctataccg
     1981 tttgcggtat ctgacccgat ccgcgtgata cctagtttga tgacaggttc agcagtcgct
     2041 gcagggattt ccatggcagt aggagttact tcaatggcac ctcatggagg gatttgggtg
     2101 atgctaattc caaatgttat gaacaattta cctatgtatg tcttggcaat tgcatcaggt
     2161 acagtcacta cagcctttat gcttggacta ttgaaaaaaa cagtgaaaga gaaaaaacaa
     2221 gacaagtgga cgaaaaatga aaatctaaca aatgaggtgg aagcgtaatg ttatatacaa
     2281 tgaaagagtt attgaaagtg gctaaagaga atcaatttgc agtaccagcc ttcaatattt
     2341 gcagctatga tatgatgaaa gcaatcatcg aagaagcaga gagattagaa gcaccagtaa
     2401 tcttagaaat tcatcctgat gaaatcgcct atttaagtga tgagtttgtt gcggcagtaa
     2461 gagcctatgc ttatacaagt aaactgccga tcgttatcca cttggatcat ggcggtacga
     2521 tagaagatgt cttacgggcg attcgaaacg gctattcttc cgtgatgatc gatgcgtctt
     2581 tgaaatcatt cgacgacaat gtacagatta cgaaaaaagt ggttgcgtta gctcatgcgg
     2641 taaatgtctc agtggaggct gagcttggaa cgattgggaa taatggttct gctgaaggag
     2701 gtgctgaaac aatcatttat acagatcctg atcaagcgaa gatttttgtg aaagaaacag
     2761 gaatcgatac acttgctgta gcaattggaa cagcgcatgg cttgtatccg aaaaacagaa
     2821 ctccaaaatt aaatatcgac ttactgaaag aattgaacca acaaatcgat cttccatttg
     2881 ttttacatgg cggttcaggt aatccggacg cagaagtcag cgaagcagta aaatacggag
     2941 ttgccaaagt gaatttgagc tcagatctta aaagcgtctt tttcaatgct ttgagagaaa
     3001 tattgagtga aaatccatcg atgtacgagc cgaatgcaat ttatccagca gctaataaaa
     3061 aggtacaaga agtggtcaaa cataaaatgg aaattttgaa cacagtaggc aaggctagtt
     3121 tatactaaaa ataaaaatgt gtggtcaaga gggtatgaca atagtcttgt cataccctct
     3181 taaccacaca cgatgttcag aagtagtttt ttcgaaaaat ttcttcttat ttctcgaagc
     3241 caatcacttc tgtcacaacc tcttttttcc tgttactata taaagtaaat ggggtgattt
     3301 tatgttgaat gaagtggaga atagacagca ggagattgtg aattatctaa aaaacaacca
     3361 atttgcaaga gtcaccgatt tgatcgagtt agtaaattat agcgaagcca cgattaaacg
     3421 tgaccttgtt tttctggaaa aaagtggatt gatccgtaga gttcgcggtg gcgccatgct
     3481 tattgacaat cgaaaaattg acgtgcctta cctgatgaag atcaccaaat tagaagaaga
     3541 aacagaaaaa cgtaagattg cagatacagc ttcttctttg attcgagatg atatggtctt
     3601 attcttggat tccagtacaa cctctttaca cttagtcaga aacctagcaa gatttgatgg
     3661 tttgcagatc attacgaatg gcatcgtcac agctgctatg ttgagtgaat atacaacggc
     3721 aaaagtatct gtattgggag gggcaattgt tccgaaacga gcaacaatca acggttcaaa
     3781 agcctataac gatgcattgt catattatgc ggatttagcg ataatgagtt gtcgcgggct
     3841 agatttcagc caaggagtaa cagaaactca tgaaggagag gcaatggtca aaaaagcttt
     3901 tagaaaacaa tcagaccggc ttgccgtttt agttacacag caaaaaattg cacataaatt
     3961 catgcatcaa gccattgctt ttcatgaaat cgattatctg gtgacaagta aagaactgac
     4021 aaaagaacag tatgcgaaag taaaggaaca ccatatcgaa tgtctgtacg gataaattat
     4081 tacgtgaatg ttctaagtgg cttcctcatt tttagatagg accttatctt tgctcgcttc
     4141 tctcagccga tggtataata atgaaaaggt tatcttgtta gataatctta cttttttatc
     4201 caggagaaag gagtgcagaa aatgaaacat gtgaaggcgt tggtagtgaa ggcaatcatg
     4261 atctgggcga ttctgtgggt cgtgctgaca ggtttatacg gtgttagctt tatggattca
     4321 acgattgttg gggtaattat tgtagtcatg atctatgtgc taggggatct gttgatctta
     4381 cgtaaagtag ggaacatcgc agcgacgatc gcagatgctg gttcagctgc agttatcttg
     4441 tggctctatc tatattttat gaatgataca gtcgatattt ggatgaaagt attgattcct
     4501 gctctattga tcggtgtggc agaatggttc ttccacaagt ggttgctaag tcaaggcatc
     4561 gtaccagatg aacggaaaat ggaataaatc aacagttaaa ctattcttat cgataaatga
     4621 aagctttaaa aataaataga tgtttaatta agaataatca taaactattt ttactcaaaa
     4681 aaccgctcag attattttca gatctgaacg gtttttttta tctattcatc aagatcaaat
     4741 ttcatttttc aatgattcaa tcaattcgcc ctctgcttca tgactatgtt ttcggccatt
     4801 aacaagatag agtgctgtac atatcaatgg aatgactccg gcaatcacat acaatcctct
     4861 aaatgaagta agagatttta gcatccccat caaataagga ccaacgccta agcctaggtc
     4921 taaaccaata aagtaggtag ataaagcaat actgattcga tgttcgcgga cgatttttaa
     4981 acaaacagcc tgtccatttg acataaacgt accataacct aggccgacta atgctccaga
     5041 gataagcaat gtcacactat tcgtcgttac actcagtaaa aataatcctg ctgttaagaa
     5101 taaatagcta ggatacatca cgtattgttc tcctttgaca tcgaaaatcc ttccagtcaa
     5161 tggacgtgta aatgtgatga ccaaagcata tacgacgaag aaaaatgacc cagcagcaac
     5221 taagtggatt acttttgtat aagaagataa aaatgataaa acacttgaat aagaaagacc
     5281 catcaaaaag gcaattcctg taatgaaaag tgctttcttt tcaataaaac tattgatatt
     5341 ccatgagcga agagatattt tttgttcttc agataatgga atatttttta caggaaagac
     5401 aaggcaggca atcgtaacaa agaagaccag tacaattgaa aaccagataa tgaaacgaaa
     5461 atcagtcata ttcagcaaaa tcattcctaa aaatggccca acagcggcag ctaaactagt
     5521 acttaatcca taataattga tgccttcccc ttttttagat gcagggatat atgcagtaac
     5581 gatagcattt gtagctgtag aaactgtacc gtagccgaat ccattcaaga atcgaactaa
     5641 atacaatgcc ccgatagttg gcgtataaag atatgctaat gttgaaagga gatagaagat
     5701 cgcgccgcct cttaaggtaa acttccgacc aaatagttct aactgtttcc ccatgaataa
     5761 gcgtgccagc aatgttccga tgatatagat cccagaagca aaacctgctt ggctcaagct
     5821 ggcgtgtaag gtgtcttgcg caatgactgc catgatgacc atcaacagat aataaatcag
     5881 gtagacaata aaattgatca atgtgattcc aataaaatat ttattaaata atttcttttc
     5941 catgtatgtt atacattccc cttaagctga atatgctttt aatttttgta tttgaacttc
     6001 tacatcgtga taattggatg gatagcgatc aacaagttgg cgaataaata aatctcttgt
     6061 agacataaac agatttaaaa attcttcgca ttcgtttgtt ggattctcat ccactgcttt
     6121 gatcaattcg atcgagtttt gatacgcatc atttaaaaag actaaagaag ctttcatatc
     6181 aaatcttgtt tgatatgctg tttctaatcg attaatgatt gtgttcatcc agtaattcat
     6241 gttttttccc tctattctta aaaaatttta cttctgcagt ataacgaata aaaaaaagga
     6301 aaaaaatcgc ataagtgatg gaaaaaggta cttaacaaat gttaatatca ttagtaaaat
     6361 acctttggac tttaaaaagt tttaaagtac tgtatgatct ttttagatga aagtttggat
     6421 gggggagcat cattggatag tagagtctta aaggaatatt tggataaaaa tgattttccg
     6481 attatacgca aaggatatca taaatatttg acattcgaag ggatggaaga ttcccatacg
     6541 tatatcttga aagagggaac ggtaaaagca agtgttattt caaatgatgg gagagaattt
     6601 aaccttcgct atatcaaaga tcttgaaatc gtctctcttt taaaagacga atattcacaa
     6661 ttcatcgatt cgccgtataa tattcgagtt gaatcagaat atgcagagtt ttatcgaatc
     6721 aatcgtgtgc gcttttggca aaatatcaac caagacccaa agctacaaca ctatgtaaaa
     6781 gagtattacc gctatcgtct gctttattcg atgaaaaaaa tgcagcaaat gctattaaac
     6841 ggaaagctgg gagctgtttg tacgcaactt tacgaattat atgatttatt cggtgtgcgg
     6901 acagaagaag ggatgctgat cgatttttcg atcacgaatg aagaaatcgc caaattttgt
     6961 ggcatctcaa ctgctagcag tgtaaacaga attttaaaac aactgaaaaa agatggtatt
     7021 atcaccgtta aagaccatca tatcgttatt ttgaatatgg acttgttaga agacaatatt
     7081 atcttttgat gaacaaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca
     7141 aacggaaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagctga
     7201 ttgaacaccg tttaccaaga ggttgtgagc ctgccgttta actctgagtc acaaggaaca
     7261 atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg aggagttggt
     7321 aggagaacac cgtttaccaa gaggttgtga aaaagctgtt ctgcatcaag taataagaag
     7381 agccaagtaa aaacagtctc ttatgttttt aacttggctg gacttatcac cgtagatgta
     7441 agcttttgaa cgccgtttat ttgcaacaaa aggggctgtg acacgatttt tgtcacagcc
     7501 ctttttttgc gaacattcat ttagcaattt ttagaaactt ctgccgccac cgccaaaagt
     7561 cccgccaccg ctagaatggg tagtacttcc gccaccgccg cttccaggag gtgggctttt
     7621 ggggattctt cttgtcgtga caaaagaatt tgtcagacga tcggtttttt cagttaattt
     7681 gatactggat ttttctcgga atggatattt gtagatgcct gatttcaatt gataacgcga
     7741 aacagtcaca aaataaaaga caagactaag gataagagcc aaaacaacag caatgatgat
     7801 ttctactgtc gtcaaaacct tatagcgtgt aattttgcca gtttcttcgt ctacacgata
     7861 atgtcctcct ggaactccgt cttccacata tgttgctgat ttagacaggt aagcttttgc
     7921 agcattgtaa taggcagcat ttgtcatctg atcataaaca tcatctaaga tcgaatcgat
     7981 tctgctatca gtcaaataat cgatcatatt accagaagtc gaaatgtaga tttcacgctg
     8041 tcccatatct aatagcaata ctgagccatt ttgatcattt ccgactgcgt ctcttaagta
     8101 attatcagca aagtctcttg gttcttctga attagatgta gtcgttacga tcaagactcg
     8161 tcctttgatt ttttcattca gcttttctgc ctgttgttcc aaagattgga tttgatctgt
     8221 tgtgaataac ccagcctcat catttaccgt agctgtatct gcatgagtag ccaccggcca
     8281 gccaacactt actagcaaaa gaaagaataa aaaaaatttt ttcatcatat caagtaacct
     8341 ccgatcagaa agaggatcgc tagcccagcg aaaatcccaa gagcggtcag tcccaatttt
     8401 ttctggctga tcggcaggac accgctgacc tttcctgttt gtccattcat tgcgtagtag
     8461 tagacttttt tacttgagtc attgcttcga taagtaacaa gccataccgg cagtaatacg
     8521 taattattta cttcgtttgt gattgaagca gaagttcgca caccggtcaa tgttgtatat
     8581 ccatttgcgg tatcttttaa cagcttctct gaatagtctt ttaattcaga ttgaatctgt
     8641 gatttgattg cctcatattc gatatctctt ttttctgctt ggaacccggc taaatactgg
     8701 cttttaaaat caattgcttt atctaacggg aaaggttgca cgccttcgac catcttttgt
     8761 tgcgtatttt ttgataaggc attttttact agttctttaa aagaaagctt gcctgctctt
     8821 gaaacagcaa attgcttcgt ttctgtgtat tcgatgtcac ctatccgcca tatgcggata
     8881 actgtaccat tcgcctgcat ggcaccatct acttcagcat ctgtagccca ataagggaaa
     8941 tacacacctg tcaacttatc gatttgatcc ttattgaaaa aagctttggg aacaaaccat
     9001 tttttcttgg tccaagcgag aaatctgttg attgcttctt ctttctcgac agcaaaagga
     9061 agtactttat ttggcaagaa ttctccgctt aaacgtcccg atagtacgac gggattatgg
     9121 cagtagtaac aataagtcgc agcagttgtc gcatcagtca cgatctctgc accacagttg
     9181 ggacaaagaa aaagatctat cgctgcggta ttatctgcag attcgtccgc tgtatctgaa
     9241 aaaccgcctg cctcgtcaac cgctttgcgc tcggcttcat tcatatcggc aagctgttct
     9301 tgggctgtaa aagtaaaatc ttcggtaggt gaaggttctt ctttgctttc ttcgccagcc
     9361 atacgcgctt ctttttgctt ttgctcatat tggctgactt cttcttctgt atagatattc
     9421 aggcagtatt cgcaatgaaa tttttggtct ttgggatcaa aagtcaacgg accgccgcaa
     9481 ttaggacatt tatgtgtaag aacatccatc agctgcacac ctttctaaat aaattaatta
     9541 acggggattc ctttaaacgg tttaccacag tttggacaga atttagggat gccgttggaa
     9601 agatccacga tctcattgca ttcactgcat cgcatttgta gcttaggctg aacgttttct
     9661 acaggtttgg cagctccgca gttggaacag aattttccgg aattttctgt cccgcaaact
     9721 ggacatgtcc aagtatccgc atttccttgt gcagtttgtt gattttgttt ttctgcttgt
     9781 tgtttgattt gttcttggtt attttgagct gcttgagaaa gataagaacc atttgcattc
     9841 attcccatac ctacacccat aaagccggtc attgctcctg cttcattttt tccggctgct
     9901 tccataccac gtgcaatgga accttgcacg tatccttcac gtacgctagg atcacctagc
     9961 atcgcccctt cgttacgcat attgatcagt ttcacagaat catcggtgta agaaatgctg
    10021 gctacagcca cagaaacaat ctccatccca cgtaattcac gccaagaatc atccaatgca
    10081 gtatccatgt atttgcttaa ttccaaactc ttagatggta cataagaaat ccgttgacca
    10141 tctgcagaca tctgattgat tgctgattgt agcgctgtta ggaattcagc taaatactgc
    10201 tcattgatat cattgatttc cacttgtgtt ttgtttttag ggattgcgtt tgtataaaat
    10261 aaaatcgggt caacgacatg aatagaataa gtgccatgtg cccgtaagaa taattctgcg
    10321 ttatagaaat tgtcaaagta gttcaacggc gcgcttgtac cgaatttgat tccctttatt
    10381 tcttggagat tgatataaaa aacttgttgt ttctgcggtg tgacgccgcc aaatttgaat
    10441 cggtcaaaag tttcagcaat tgcttctttc agtgttccat tgaacatgga aggagctgcg
    10501 tcatttttaa tggtgtaata accttcctca gcggtataat cgatgatttt tccaccatcg
    10561 accaaaagca tcatcatgtt tggatagaca tggacgactg ttccgtctgt taaaacatct
    10621 tctgttcctt tacgattgga gccacgtttg tcatctttgc ggactttgac accttttgtc
    10681 atgaccgttg tatcactcat attgtctggt tcgatgactt ctagccattg atctgccaga
    10741 ccgccgccaa ccatacttgt tgctgctttg ataagaccca taaaaaattc ctcctctgat
    10801 tcagctagtg ccaaacaatt attgtttatt tattatacca taggaagatg tgaaacttct
    10861 cggactagag acggaattga aatggaaaat tgcgtattgt ttaaatacct gaaaaagccg
    10921 agaaggatag tagttttttt acctaatatc acgtataata agagatagtg aattttttaa
    10981 aaaaggggga tccttatggc atatcaagca ctttatcgag tctggcgttc gcagcgtttc
    11041 gaagacatcg ttggacaaaa agctgtgaca cagacactaa aaaatgctat tgtttcccac
    11101 aaaacctcac atgcctactt gtttacagga cccagaggaa ccggaaagac gagtgcagca
    11161 aagattttcg caaaagcaat caactgtccg aacagtaaag acggtgagcc atgcaacgaa
    11221 tgcgaaatgt gtcgatcaat tactgctggt acgcaagaag atgtgatcga aatcgatgct
    11281 gccagcaata acggagtcga agaaatccga tttatccgtg atcgggcaaa ttatgcgcct
    11341 acaaaggcag cgtacaaagt gtacattatt gatgaggtac atatgctttc aacaggagct
    11401 ttcaatgcct tgttgaaaac attggaagag ccaaaagaaa gtgtcatatt catcttagca
    11461 acgaccgaac ctcacaaaat accagctacg atcatttcac ggactcagcg atttgatttt
    11521 aaacggatca atacggcaga tattgtcgaa catcttgaat ttatcttgaa agaatcgact
    11581 atcagctatg aaccagctgc attgaatgtg attgcccgtt ctgcagaagg cgggatgcgg
    11641 gatgcattga gtattcttga tcaggcaatc tcgtttagtg aaggaacaat tactttagat
    11701 gatgccatgc aagtgacagg tagcttaact gacgaaatga tggacagtta cttgagtgct
    11761 tgcgtgaaaa aagaagtacc agaagcattg gaaacattga accaaattct cgcagccggc
    11821 aaagaatcac gtcgctttct agaggatatg ttacaatact gccgtgactt gctgatgtat
    11881 cagcaagcac ctaacctagt tgaggaacaa tcgagtacga tcagaagtac atttacagaa
    11941 ttggcacaaa ctgtttcagc ggatcagctg ttttcaatga taaagatttt gagcgatact
    12001 caaaatgaaa ttcgttttac caatagtgcc gctatttatt tggaagtcgc tacagtcaaa
    12061 cttgcacagc taccgtctgc ttctgttcct tcagcagatg tagcatttgc agatgatcag
    12121 atagtaaaac agctacaaca agagattaag gaactaagaa acgaaatcaa ggaactacgc
    12181 agtaatacag gaattgagaa tacaaaagta cagccggtac agcaaacaaa tcataaaaaa
    12241 cagacaagta cctatcgtgt accgacggaa cgagtatata aagttctgcg ggaagcgaca
    12301 agacagcatc tgaaccaagt aaaagaagta tgggaagact tgctgatgag tctatctgtc
    12361 actcagcgag caatgcttaa agcaagcgaa ccagttgcag ctggacctac aggactagtg
    12421 attgcgtttg attatgagat tgtttgtcaa agagcagcaa atgacgaaga attgcagctt
    12481 tcggtacaca acaacttaag ccgaatgatc aaagattatg cgcctgatcc tgtttatatt
    12541 acaagagaaa gctggccaga acttcgaaga aattatttga cgcaggcaca agaagaggga
    12601 acagaaaact cttttgcttc tgaagactca gaaggagaaa tcgagttgct tcctcaagaa
    12661 caagaagtac cagaagaaac acttgtagta aaagcagagg aactgtttgg ctccgaagct
    12721 gttacagtgg tagatgatta ataaaaagga gtagataatt atgatgcgtg gaatgggcaa
    12781 tatgcaaggc atgatgaaac aagtacaaaa aatgcaaaaa gaaatggcag aagcacaaga
    12841 gctgctaaat aaaacagagt ttacaggtaa agccaccaat gaattggtca aagcggtttt
    12901 tacaggcgat cgtcgcatga aagatatcca aatcaatgaa gaagtcgttg atcctgatga
    12961 tatcgagatg cttcaggatc ttgtcgtaat ggcagtcaat gatgcgatcg cacaaattga
    13021 tgtggaaact gagaaaaaat tagggaaata cgcaaaaggt ttgccaggat tttagtttta
    13081 aactgaagga gtaatgaata tgcaatatcc agaaccaatt gcgaaactga tcgacagcta
    13141 catgaaactt ccaggaatcg gtcagaaaac agcgacaaga ctcgcctttt atacgatcga
    13201 tatgaaagat gaagtagtaa atgaatttgc taaatctttg ttaagtgtaa aacgcgattt
    13261 gcatttttgt agtatctgcg gaaacatcac agaagaagat ccctgcgaaa tatgtagaaa
    13321 tccttcacgt gatcgaagcg ttatcctagt ggtcgaagag ccgaaagatg taatggcaat
    13381 ggaaaaaatg cgagaatatc acggacttta tcatgttctc catggtgtgt tatcaccgat
    13441 ggaagggaca ggtccagaag acatcaatat ttcttctctg ttgcagcggc tgcatgatgc
    13501 agatgtaaaa gaagtgatta tcgcaacaaa tgcaacaaca gagggagaag caacagctat
    13561 gtatctctca cgtctgatca aacccgcagg tatcaaagtg actcgtctag cacatggtct
    13621 gtctgtaggc tctgatatcg agtatgcaga tgaagttact ttattgaaag ctgtcgaagg
    13681 aagacgtgag ttataaattt ctaattaagt gttttttcag atacaatata aaagcagcac
    13741 aagagatggg ggcaacaatg tgaacggact atttattaca atcgaggggc ctgatggtgc
    13801 aggaaaaacc agcatcttga atgaacttta ccctcttttg aaagaagtag caaaaacaga
    13861 aatcattcaa acaagagaac caggaggcat tccgattgct gaagagatcc gagcagtgat
    13921 ccttgatcca aaaaatgatc ggatggatga acgtacggaa gcactgcttt atgcagcagc
    13981 aagaagacaa catctagtcg aaaaggttct gcctgctctg gcaaaaggga aaatcgtttt
    14041 atgcgataga tttgtcgaca gttctcttgc ttatcaaggt gcaggccgac gcatcggcgt
    14101 taccgagatt gctcggttga atgagtttgc tacagaaggt actacgccgg attttaccct
    14161 ttatcttgac gtagattcag acaccggatt aagaagaatc aagaaaaaca gacaaaatca
    14221 aatcgaccgt ttagattcgg aaggtttgga attccaccag cgtgtacgtc atgcttactt
    14281 aaagctggca gaagagaatc cggaaagaat ccacaaagtt gatgcaagaa aaagctttga
    14341 agaagtgctg caaacaagtt atcatacaat tattgaacag tatccgcaat tttttgaaaa
    14401 ctaggaaggt gaacgtttat gaaaattatt ttagcgatta tccaagacaa agacagcaac
    14461 cgtttatcaa atgaattgat tgatgcaaat atccgtgcca caaaactatc atcgacaggc
    14521 ggcttcctta aggctggaaa cagtacgttt atcgtgggta ttgaagatga ccgtgtagaa
    14581 gaagcattgg aaatcatcaa aaaaacgtgt gaatcaagaa agcaatttgt atctacacct
    14641 gttacactgg atatttcgat ggatgggggc gtcccttatc cagtagaagt agaagtaggc
    14701 ggtgccacag tcttcgtctt acctgttgaa ggattccatc aattttagga ggagctgagc
    14761 tatgaatcaa gaaataaact tggctcaaat gcaaccgatc gtgtatcagc agcttcaacg
    14821 gagttttgag catgggcgta tcgctcatgc ttatcttttt gaaggggaga aaggaacagg
    14881 aaaacatgaa gtaggtatat ggcttgcaca gcacctgttc tgtacccaaa tgaaagacaa
    14941 tctgccttgt ggaaaatgca acaattgtca gcggatcgaa aagaaagaac atccagatgt
    15001 tttggttatt gaaccggaag gacaaaccat caaagtcgat cagatcagac gtttgcagac
    15061 ggaattcagt cgcagcggtt acgaatcaag aaaaaaagtt tttttgatca aagaagctga
    15121 aaaaatgaat agcagtgcgg caaacagttt gttgaaattc ttggaagagc cccctggaga
    15181 ttttttagcg gtgttagaaa cagatgcagt aggaagaatt ctccctacta ttcaatctcg
    15241 ttgtcaagtt ctgcattttc aagaactttc gaaagaagca ctgatccatc gattgcaaga
    15301 agagcagatt ccattggaaa aagcaaaact tttggctttc ttaacaaaca gtttaggaaa
    15361 agcagttgaa atctctcaag atgaatggtt taatgatgct aaggacttga tttatcaatg
    15421 gttcgtttac ttgcaaaagc aagatactca agcctttatc tatgtccaaa aaaaattggt
    15481 aaaatcattt aaagaaaaaa cacaacagtt tacaggatta tctgtcttga tgttttatta
    15541 tcaggaagca cagcgtcaag cagtagcaaa cggcgaatat ggcaaagtga aacagataaa
    15601 ccagataatt gaacggatat tgatcgcaga gcagaaacta cgcagcaatg tcagttttca
    15661 ggctgttgcg gaacagttcg ttttgcatac gattttttag cttgccgcaa aggatgatga
    15721 tcaaggagga tggaaatggt agaagtagta ggtgtccgat atagagatgc aggtcatatc
    15781 tattattttg caccaggaga ctctgaatat gtttatagtg acaaggtatt agtcgaatct
    15841 cagcaatcct tacatattgc tactgttgtc cttcctaaaa aagagattga tcccaatgac
    15901 cttcctgaag ctatccgtcc gatcttgcat aaagcgtcac aagctgaatt agaaaaagac
    15961 aaaaaaaaca aaaaagatgc ttatgatgca ttgaaaatcg caaaagaaaa agtgcagttg
    16021 cgtgagttgg aaatgaaaat ggtcaaagcc gaatacacat ttgatcgaaa taaattgatt
    16081 ttttctttca cagcggacgg gcgaattgac tttagagaat tggtaaaaga tctggccgct
    16141 gtatttcgta ctcgtattga gcttcgacaa attggtgtcc gcgatgaagc aaagataata
    16201 ggcggaattg gtccatgtgg gcgtccatta tgctgttctt cttttttagg cgatttcgtg
    16261 cctgtatcaa tcaaaatggc aaaagatcaa agtttatctt tgaatccaac aaaaatttcc
    16321 ggtttatgcg gacgcttgat gtgctgtctg caatatgaga gcgaagaata cgagacagcg
    16381 aaaaaagaac tccctgactt tggaaaagta attgctacac ctgatggtaa agggaaagtc
    16441 gtagggttga atctgcttag ccgtatcgtt agtattcggc tgactggacg ggaaaatcct
    16501 gtcgaatatg aatgggatga attgaaagaa tttatccaag taggtgagat gaatggataa
    16561 gagatcatta tacgacggat tgaatcaatt agaatcagag ttgagaaata cattaacaga
    16621 acttgttgaa atgaagcatg ctttgcatga gatcgtagaa aaaaatacaa ctttggagat
    16681 ggaaaatcaa cgtctgcggg aacacctgcg ggaattgaac caagttgcac aagctccagc
    16741 tgaaaatgtg aagcaggaac tttctaagtc tcgtatgaat cttgaaaaaa tttatgaaga
    16801 aggattccat gtctgctacg atttatatgg atcaagaagg gacaatgacg agccttgtgc
    16861 gttttgtcta gaagtgatct atcgcgaaag cggtcgatga ccaataacaa gaggagactg
    16921 gagcggagaa atactgctcc agtcttttta ttaaggagat tgtgacagat gtataatcaa
    16981 aaaagtttca agggaaatcc ggtatatggg gatttatatc ttgtaccgac gccaattgga
    17041 aatttagaag atatgagcta cagaagtgtt cgtatgctgc aagaatccga tcttatcgca
    17101 agtgaggata cgcgtaatac acaaaagtta ttgaatcatt ttgaaatcca tacaccccaa
    17161 aaaagtttac atgaacataa ttataaagaa cgtgtccctc aattgattgc tttgttaaaa
    17221 gaaggaaaaa cgattgctca agtcagtgac gcaggaatgc cttccatcag cgatcctgga
    17281 catgagctag ttttagcctg cataaaagaa gggatttctg tgatctctat cccaggacct
    17341 acagctggga tgacggcttt gattgcttca gggctagtgc ctcaaccatt tttattttat
    17401 ggcttccttc cacgtaagaa aaaagaacag aaagaaacat tgaaaaagct aaaagaacag
    17461 acagttacgc tgatttttta tgagtcacct tatcggatca ctgctacatt gacgaatttc
    17521 ttagaaattt ttggaaatcg ccaagtcgtt ttgtgtcggg aattgacaaa ggtccatgaa
    17581 gaatacctta gaggaagtac ggaagagcta ctcgcttata tcgaagaaca tccagtaaag
    17641 ggtgaatgtt gtctgcttgt agaagggaat ttgttcgaaa tgccagtgac ggaagttgat
    17701 gaagagttgg gaacgttaaa ggaacaagta gaagcaaaga tcgcttcagg cgaaaaacca
    17761 aatgctgcta tcaaagcagt agcgctgaaa aatgggctga aaaaacaaga agtctaccgt
    17821 cagtaccatg aattagactg agatagtata agttgtctat aatgaaagac taatgaggaa
    17881 atcagctact aacttttcaa atctcttgaa cgcgaacgaa tgttcttgta taatgaataa
    17941 gaggtgagga tgatggagct gcaatttcct ttacataatg atacatcaag aaaaatcatt
    18001 catattgata tggatgcttt tttcgcttcg gttgaagaac gagatcatcc tgagtttcgc
    18061 ggacatccat tagtaattgc cagacacccc agtgacactg gtgggcgtgg agtagtgact
    18121 acagcaaatt atgaagcaag aaaattcgga attcattcag caatgagtgc acaaaaagcg
    18181 tatgagcttt gtccgcaagc catctttaag cctggcgacc atcataaata cagcgatatt
    18241 tccaaacaag tacgggaagt attctatcgt tatacagata ttgtggaacc agttagtatc
    18301 gatgaagcgt atcttgatgt gaccgaaaat aaaatcaatt gcaagtcagc catcaaaatc
    18361 gcccgaatga tccaagcaga tatttgggag agtgtccagc taacatgttc tgcgggagta
    18421 agttacaata agtttttggc caaattagca tcagactatc aaaaacctag aggaatcacg
    18481 gtagttgccc ctcaagacgc tgtgccattt ttaaaagctt tgccaattga aaaatttcat
    18541 ggggtaggga agaaaactgt acctagaatg catgagctag ggatttatac aggaaaagac
    18601 ctatatgaat gcacagaaat gatgttgatt cgaaattttg gaaaaatggg ctattctctt
    18661 tatcgtaaag tcagaggaat ccatgattct ccagtaaacg ttacaagaga gcgaaaatct
    18721 gtgggaaaag agcatactta tgggcagccg ttgcaaacgg aagaagcagt gctgactcag
    18781 ttgcgccaac tagctgaaaa agtagaagaa gcactgagaa gagtccaaaa acatgggaaa
    18841 acagtagttt tgaaggtcag gtacacggac tattctactg tgaccaaaag agtgacattg
    18901 ccagaatata tctataaaaa agaagcactc ttttatcaag caagccttat atgggaggaa
    18961 atcttgggag tagaaaaagg aatccgattg ttagggatta ctttgacgaa tctggacccg
    19021 atgacttatg aaaacatcgt ccttccatta tgggaaaatc aagaaatata aaaacagctt
    19081 tgagagttga aaccggaaat ccgttttctc tcccaaagct gtttttatat caagtcttgc
    19141 tttttgattt gttcataggt ttctgttgca tccgtacatt tttcccaaat cacaacttga
    19201 ttggattcta aagatttttg gacgtcaatg atccgctggt tgctacttcc gcgaaattgt
    19261 agttttaggt cacgtttgct taattcaaag cgtccgtcaa caaggatatc gatttgcgaa
    19321 aggagttcta atttatcttc tgaatcttgt agcaattcat caaaggtata gcctgtccat
    19381 gaccagatat cttttgtcgt accgaactct tttcggatac gtcgtacgac ttgcagacaa
    19441 acatctgtat tcaaaaaagg ttcgccacca agtaaagtta atccttgcac gtaatcgttg
    19501 cgcaagtcag cgatgatttg ttcttctaat tcaggtgtga atggtttgcc atatcggaaa
    19561 ttttgtgcag ctttgttgaa gcagccttcg caggcaaata agcagccact aacgtaaaga
    19621 ctgttgcgga caccttcacc atcgacaaaa ttaaacggtt tgtagtcagc aatatagttt
    19681 tggctgtagt cttttgctaa ccattctttt ggttttggat ttctcataaa aaaacttctt
    19741 tcatttaagg ttcaaagata tagctattga agataaaatc tactcgacca cataaataag
    19801 aacaaactga cctaaatcca ttgttcaaga aagcttgttc ttattttgat agagggcgtt
    19861 caaagataca aagccatcga aagagggtgg tgaaaaaaga cttgtcatag cctcttattc
    19921 tgaataaacg gtgttcaaaa gcttgcatct gcagtaataa gcccaactaa acgaaaaata
    19981 tgaggaacta tttttgttta gctattctta ttacttgatg caggacagct ttttcacaac
    20041 ctcatttcat gtgtttcaca cgtgaggaaa tttctttatg gcggccatgt accatcggac
    20101 gagcttgcgg atttcctaaa tagccacaag tacgtttgac tacatcacat gtttttggat
    20161 catgatttcc acattctgga cattcgaacc ctcgttctgt cggtttgaaa tcaccttcga
    20221 aaccacattg atagcaatga tcgattggcg tattcgtacc aagatacccg attttgtcat
    20281 atgcaaaatc ccatacagct tctaaagctt tcggattttg ttggagcata gggtattcac
    20341 agtagtggat gaatccacct gaacaatatt ttggataatc cttctcaaat tccaattttt
    20401 caaatggcgt tgggttttta cgcacatcat agtggaaact gtttgtataa tattctttat
    20461 ctgtgatatt ttcgatgatg ccgaattttt ctgtatccaa acggcagaaa cggtcagtta
    20521 gactttcact tggagttgaa tagacactga aatgataacc atattcatcc ccccatgcat
    20581 ctgcattagc ttttaattct ttgacgatat caagtgtgaa agcttttgct tctgggtttg
    20641 tttcccattc gccaccgaag aaagctgaag caacttcata caatccaatg tagcctaacg
    20701 atacagtagc tcgacggttt ttgaataatt cattgacaga atcggtacgt gaaagacgtt
    20761 tcccgaaagc accatacata tataaaattg gcgcatttgc tggaatggct tctttacaac
    20821 gttctacacg atagagaagc gcatctttca tgatttctaa gcggtcagac agtaactgcc
    20881 agaatttatt ctgatctcct tttgattcga tcgcgattct tggcaaattc aatgtaacaa
    20941 cacctaaatt cattcgtccg acatttactt cttgaccatt ttcgtctttc cacccttgca
    21001 agaatgaacg acagcccata ggtactttga aacttccagt taattcaacg attttatcgt
    21061 aattcagaat atcaggatac attcttttcg ttgcacattc caatgctagt tgtttgatgt
    21121 cgtaattagg atcttcaggg tttaagttca cacctttttt caaagtgaag atcagtttag
    21181 ggaagatagc tgtccgcttt tcactcccta atccattgat tcgaatctgt aaaattgctt
    21241 tttgaatttc tctttcaaac cagttttctc ctagtccaaa tcctaatgaa gtgaaaggag
    21301 tttgtccatt tgaagtaaat aaggtattga tttcatattc caaactttgc atagcatcga
    21361 agatatcttt tttggttttt gcttttgcat attctttttg gcgttctggc gaatcgatcc
    21421 attcttccgc gtcttttaga tgttttttat agttcaattc tgcaaaagga gcaagcaatt
    21481 catctgttcg gtcggcagaa cagccaccat attgacttga cgctacattg gcaataatct
    21541 gtgagatttg tgctgtggcg gtctggatag attttggcga ttcgacttcg gcattgccga
    21601 ttttgaaccc attgttcagc atgcctttga aatcaatcaa gcagcaattc gtcatcggtg
    21661 tataaggatg ataatccaaa tcatggtaat ggatatcgcc tttttgatgc gcatttgcta
    21721 tatgtggtgg caacattttc agtccgattg attttccaac gatcccggct gtcagatctc
    21781 gctgtgtatt gaaaacatta ctgtctttat ttgcgttttc gttcacgaca gtttggtcct
    21841 tgttgattag cttttcaatc gaaaagttga tatctgttgc tttactgcga gcaaaatctc
    21901 gtttggtacg ataattgatg tactcttctg ctaattcata ttcgtttttt tctagtaata
    21961 tatgttccac gatgttttga atctcataga ttttgacatt ttcagcaaac cggcttttga
    22021 tttcttggac aaccaagtct gcaatcattt gaattttttc ataagtaagt ggtgataatg
    22081 agccgtgaat tttcttttct gctttgatca gtgcttcatt gatcttttgt tcatcgaaat
    22141 caacatggcg gccatcgcgt ttgatgactt tcatctggga tgtctctggc tgctgagtaa
    22201 cgacagtttt ttcttcataa tttactttca ttatcttcaa ctcctgctaa attgttcttg
    22261 tctatcataa aacaaaatcg gggaaggagc aactaaatat cggctatata tagtattcaa
    22321 tgtgctgtat aattggattt ctatactata tgtagtgtat attttattgt gaaaaaaggt
    22381 gaaaacttgt agctggtgga tttgtttttt gcatatttaa ttttgctgaa taaaataatt
    22441 gaataaaatt ttttattcag tccaagtaaa agtgacaaaa acataagagc aaattattcg
    22501 tagatatgct actatgcaaa taaatagaaa tgaaaaatga aagaggagga gaagaattgg
    22561 aaaagatgat cgaagtgaaa catctaagta aaagctacgg cagcaaactt tctcccgtca
    22621 aagccttaga taatatctca ttcacagtag aagaaggcga gtttgttggg attatgggcc
    22681 caagtggtgc aggaaagaca acgctgatga atatcttgtc cacgatcaat ttgcctacga
    22741 tgggcagtgt ctcgatccaa ggaaaagaaa tcacaaaaat gaaaaacagt gagctcagtg
    22801 actttcgtcg aaaaaaacta ggattcattt ttcaagagtt caatttgatc gataccctaa
    22861 atgcaaaaga caatatccta ttgcccctag cagttgaacg gatgactaaa gaggaaatgg
    22921 aaaagagagt aagacatgta gctcaattgt tgaatataga agaactgctc aaacggtatc
    22981 ccgatgaact ttctgtcgga cagagacaac gaattgcagc tgctagagca cttgttgttc
    23041 agccacaagt gatttttgca gatgaaccaa ctggctcttt ggactcgaag tcggctacag
    23101 aattgttgaa ctacttgaag accatgaatc aaaaagaaaa agcaacgata ctgttagtca
    23161 cccatgatcc atatacagca agctactgcg atagaatttt atttattaaa gatggtgtga
    23221 ttttttctga agttgtcaga agagggacaa gaagagagtt ctttgagaaa gtaatagaca
    23281 tgcaggcgac gattggcgga ggaggaaaaa tgaatgctgt ataaactagc cgttaaaagt
    23341 ttttttcggc agtcacgagg ctatcttgtt tattttttca gtttgacttt atccgtaatg
    23401 atctattatt ccttcagcgc aatgacctac gatcaatctt tagtcagaag agcaagtcaa
    23461 gatacttcga tagatggtgg attgagtttt ggtggattta tcattactgt tgttttgctt
    23521 tttttcgtat tcagtgccaa ccgatttttc ttgaatagaa ggcaaaagga aataggcatc
    23581 tatcagcttt ttggtatgaa taaactgcag atatcaggta tatatgtgtt agaaatcatg
    23641 ataattggat tgttcgcctg tatttctggg atattactcg gtattatttt ttccaaactc
    23701 ttttcaatga ttttggttcg aatgatggat atggatctta ctagtccatt ttttatctcc
    23761 attccatcag tagtagatac tttatttgct tttttcatca tccttttagc agtatctgta
    23821 tattcaatat ggaaaatatg gcgctatcca atgattcgaa gttttggaga aaaagaacaa
    23881 gcagatagtt caacaatgcg cttcaggaca aggcaccgat tactcgcagt catcgggtta
    23941 ctacttttaa cgagcggata ttttggagct agtcatttta gggaaatcac ttcatggatg
    24001 atcagttatc attatcttga tacattagtt ttcttttttc cttttttaat ttttttcgtt
    24061 tgtgtggtcg gtacttattt gtttttctgt tatacatttc ggttattttt gatcatattg
    24121 agtaaatgga agatttatta ctatggtatc aattttttga taatgggtaa cacgcaagtt
    24181 catttgctca aaagttggcg tacaaattct ctgattacag tcattctcgg aatttcttta
    24241 atgacaattg gcggcacggc tagtatctct actattttat cctaccagga gaaagtttcc
    24301 tccccgatgg actatcagtt tgatgttgag acagagaaaa aaatcaagcc gattctagca
    24361 gaggaagggc agaagataac taaagaaatc accttgcatt ataaagtcat tgggagtatc
    24421 tatagtcaaa atctcgaaga acctatgttt caaactgcta atctgatcac ggaaacacaa
    24481 tatcaagcct tcagaaaagt taatccagat ttgccgaaca tttctttgaa atcacctggt
    24541 catactgttt tgcttgatca aatgcaaact ctttttcgga atatttcatt atatggatct
    24601 agtattggac tgccagataa tcaagaattg aagattcaac aaatgcttcc aagtgtatta
    24661 ggtgacgaaa caatggtata tctaagtcct gtactgattg tagatgatac cgtttttgaa
    24721 aaagcaaaag gtgtggatta tcaagtagtc aatgtagatg tatcaggtgg aaataatgaa
    24781 aaaatagatg aacgactgag caatgacctg tcgataaagt ggctcaatgc tgtttattat
    24841 tcttatgata tcgtaaatgg aagtctacaa ggagaaatta gcacaaagaa acttccggat
    24901 gaccaaatga aggaagcaca atttagccaa gaaagctctc gtttgaattt ctcttccagc
    24961 tattcgaaat tgcgtgcagt taatcggcga atcggtatca atatttttgt cacactattt
    25021 gtcgggatga tcgtgattat tgctactggt agtattttga cagtccggca attagcagaa
    25081 gcagaggaag aaaaagaaaa ttatcaccta ttgactaagc tggggattcc acaaagaagg
    25141 atcagacgga tgatcttcga gcaaaacgca cttaccttct ttccacccat gatattaggg
    25201 atcactcacg cagtatttgc aatcaatgtc ttcactcagt atataaaaac tgccgattac
    25261 tggttggctt atcttgtgag tggcttattg atccttatct atcttttgct ttatgtcatt
    25321 acgagtcagt tatattgtcg gattatcgag gaatgatata cggaataaga caagataata
    25381 aatagaacta aattttgaat accatttatt tggaataaga ggttgtgaca cgatttttgt
    25441 cacaacctct ttatttttta tattttttaa aagtacgaga aattataaag aaaaaagcag
    25501 tgatttgatg tgctattttt ataaaagcta tgtgacaaaa ctgttagtaa aaaaacggtt
    25561 tctgtaagct agacacatgt ttctttttgt caaaattagt tacactttgt gtgaggttat
    25621 atgaggaggg aatccaatga acaaatggcg ttctaatcca aaattgaatt attggggaaa
    25681 attcatcatt cgaacaattt tttatagtgc agtactgctg ttcctgattt atctgtatca
    25741 ctataaaaat attcaaggag gaacttttat ctataacgaa ttttaggagg aagagtatgg
    25801 aaatcaaaac gattattgaa gcaatcgatg attggggaat aaatgaacct gatcgagttg
    25861 cttatcaggc ggatgagacg catacttttg gtgaattgaa acaagcatca gacgcacttg
    25921 cttattattt agaaaaaaag gtagaaggcg atggaccaat tgtcgttttt ggcaatttgg
    25981 agtttgaaat gattgtctca tttctagggg ttgtcaaatc tggccatgcc tatttgccga
    26041 ttgaagagca tacacccaag gagcgtatcc tatcgatctt tcgggtggct aaaccatcta
    26101 tggtcatcag tatcggggac tggatagaag atattccttc ggttcctgtc ataacaaaaa
    26161 aagaatttca agaaatcaag aagataccag taggatttta tcccagaaat agcgtaaaag
    26221 gtacagaaaa tttttatatt atttttactt ctggtactac tggagaacca aaaggcgtac
    26281 aaatcagtca tgataatcta gtcagctttg ttcaatggac gatggaagac tttgggatca
    26341 agcctggtat gcatttctta gcccaagcgc cattttcttt tgatttatcg gtattttcta
    26401 tttatcctgc attagtttct ggcggaatgc tgaagccgtt aaataaagca gttgttcaag
    26461 actttcgtca attattcgcg acattgccag ccttgaagtt gaatgtgtgg gtttctactc
    26521 catcatttat ggatatttgc ttgatggaac ctacattcaa tggagaaaat gtgccggaat
    26581 tggacatgtt tttattttgc ggagaagaat tgacgaaaaa aactgcagaa agtctacttg
    26641 atcgattccc aaatgcacgg atatataata cttacggtcc aacagaagca actgtagcta
    26701 tttcaagtat tcagattgac cagcatgtac tagatagtta tgaccgacta ccgattggct
    26761 acgtaaaaaa agacacgaaa gtttctattg tccaagaagg taaacctgtt tcaaaaggag
    26821 aaacgggtga aatcattatt gcaggaccaa gcgtatcaaa aggttacctt aacaatcccg
    26881 aaaagacagc tgctgcgttc ttttgtcaaa atgacttagc aagttaccat acaggggatg
    26941 caggtagact agatgaatat gggcttttat tttatgaagg acgtatggat cagcaggtca
    27001 aattacatgg ataccggatt gaactcgggg atatcgaaca ttatctgctc caagacaacc
    27061 gaatcaaaca agctgtcgtc gtaccaaaat accaaggaac aaaagtacag cagctggttg
    27121 cttttgtcgt attagaaaac aaaacgaaac agccggattt tcagttgact aaatctatca
    27181 aagaacaatt actagaagtt gtaatggatt atatgattcc tcagaagttc cattatgtcg
    27241 atctgctgcc tcagacagtt aatggaaaaa tcgatcgaaa aaaattaaca gctgaggtga
    27301 atcctgaatg atgttacctc atatgatccc ttatgcagag ccgttttatt tttttctttt
    27361 agccattgcg cttgtaccga tcgttctatc tttattgata tgggaaaaaa gattaccagt
    27421 ttatcaatca gcagtgacac ttttcttttt atttgtcagc tttggaggta attattggca
    27481 acagggagcg gcgctgattg ggtatgtttt gtggcagacg atacttgtat ggggctattt
    27541 tgtttatcgg caaaggaaaa atcagacagg atggtttttt gccgccgtta ttttagcgat
    27601 aattccactg tttttaacga aagtgactcc tttttttgaa catggaaaag catcgttact
    27661 tggtttttta ggaatctctt atttaacctt taaatctgta caaatgatca tggaaataag
    27721 agatggcatg atcaaaacat ataagccatt tcgttatatc cagtttctgc tgttctttcc
    27781 aacaatctct tctggaccaa tcgatcgcta taggagattt gaaaaagatc agctccatcc
    27841 gcctgttcgt gataaatatg ttgatctttt gggaaaaggc gtccaaaata tttttgtcgg
    27901 ttttttatat aaattcatta tcggttatta ttttggtcaa gtactgcttc ctgtagtggg
    27961 acgcattgcc ttacagcatg gtggtatttc atgggcatta gtaggttata tgtacgtgta
    28021 cagtatgtat ttgttttttg attttgctgg ctatagctta tttgcagtcg gtacaagcta
    28081 catgatggga tatcagacac caatcaattt caataaacct tttttatcat ggaatatcaa
    28141 agaattctgg aatcgttggc atatgacgct gtccttttgg ttccgtgatt atgtatatat
    28201 gcgattgatg ttcttcatga tgaagaaaaa attttttaaa agcaagatcg taatgtcaaa
    28261 tatcggttat tttgctttgt ttcttctaat gggtatatgg catggattga cgtggtacta
    28321 catcgtatat ggactgtatc atgcttgtct gatctgtctg acagatgcat ggatccgatt
    28381 taagaagaag cataaagagc agttgccttc taacaaattt acgcatggct tagccgtatt
    28441 tttgacattt caagcagtat gttttagctt cctgattttt tcaggatttt tagataaact
    28501 tttttttagc taacgaatag tgacatatta atttatataa caaaggagaa aaggaaaatg
    28561 gaagaacaaa ttttatcaat cttagaagaa ataacaggaa cagatgaagt aagaaaaaat
    28621 cgtgatattg atctatttga tgaagggttg cttgattctt tagcatctgt tcaattatta
    28681 gtcgagctag acggagagct ggatatccaa gtccctgtat ctgaattcga gcgagaggat
    28741 tggagcacac cgaataaaat cattcaacaa gcaactgcat tgaagggttg agtatgaaaa
    28801 agaaactttt tgctattttc ggcccggttg ttttagctgt tggcttactg tttgtgtttt
    28861 ttacctcctc ctatcaagta gatatctcta atccagaaac gattagacgt gcctcttctt
    28921 ccatgtcagt gaacgtgttg aaaggagatg cgataaaaaa ttatgcatta tctgaaaaac
    28981 aatatattcc tttttttggc tcaagtgaat taagcagaat cagtccattt catccgtctg
    29041 ttctggcaga aaaataccag cgaaactatc gtccattttt gctgggagca cccgggacac
    29101 aatcgttaag ccaatatatg atgatgcgtt ctgcaggaga tgctatgaaa aacaagaaag
    29161 tcgtctttat tatttctcct cagtggttcg ttaaaaatgg tgtaaaaact gattacttta
    29221 atacgtatta ttctgaactt caaacatacg actggttgtt ttcaatgaag aaagtaacgc
    29281 ctgctgatcg ctatttagct agaagattat taactttctc aaaagtaaaa gagaatgata
    29341 cgttgacggc gattctgcaa acgatcaaaa aagggaagct acctttacct gaatctttga
    29401 atcagctgcg cagccaatgg aacatgctga agagagagga tgaagtattc agcaatattg
    29461 ggttgaaaga tcgacagcaa aaaatcgatc atgagtcaaa acgattacca aaacaatacc
    29521 aagaaacaga attatccatt ttagcaaatc aaattggaga acgagaaacg acgaataatc
    29581 cattcgggtt gaaaaacgat ttttatacgc atcgtatccg agcccacgag ccagagctca
    29641 aacagtcaca aaaaaattgg gattatcgtt tttcgccaga attttctgat tttcagctgg
    29701 tcttggatca attagcaaaa aaccataacg aagtattgtt catcatccca ccggttaacg
    29761 agaaatggag cgattatacc ggactatctc aagaaatgtt acaaggattt gccaaaaaga
    29821 tcaaatttca attaaatagc caaggattca atcgaatagc tgattttgtc aatcaagcgg
    29881 gtaccaacta ttttatggaa gacacgatcc atctaggctg gaaaggctgg ttggctgcag
    29941 atcaacagat cagaccgttt ttagaagaaa atcatattac tgctagtaag tatcatcttg
    30001 acgatgcttt ttttagcaaa tcttggcaac atcaaatacc agataaacta caattaaaat
    30061 aaagaaaaca ggcgagtgtt gctcgcttgt tttctttatt tttgaatatt ctgaataaaa
    30121 gataaaaata ccaagtttgc ctgaacaaaa atcataagca atggtataat cacaatatga
    30181 atatagaaat gggggaaaac atttggatac aaaagaagaa cagctactta ttgatttaac
    30241 ttctgcaaaa ggagtacctg gaaatgaaga agaggtaaga gaagtattca gagaatatgc
    30301 caaaccattc gctgatgata ttttttatga cggtttaggc agtgtgattg ccaaacatgg
    30361 tgctggcgga ggccccaagg tctttatttc tggacatatg gacgaagttg gttttatggt
    30421 aacaaaaata accgaaaaag gattcttgga attccaaact cttggaggtt ggtgggggca
    30481 agtcatgctt gctcagcaag ttgaaatcaa aacacgtgaa gggaaaatcg tccacggtgt
    30541 gattggttcc aaaccaccac atgttttaac acctcaagta agaaataaac cttatgaaat
    30601 aaaggatatg ttcattgata ttggcgcatc aagccaagaa gaagccaaag agtggggcat
    30661 acgtcctgga gatatggtca ctccatatat tgaatacaaa cgaatgaatg gcagtaaata
    30721 tttactggca aaagcatggg ataatcgtat cgggacagct gtttctctgc gagtattaga
    30781 gaatctatct aaagaagcac acccaaatgt tttattcgca ggaagcgatg tgcaagaaga
    30841 agtaggcttg cgaggtgctc gaacaagtac acaccttgta aatcccgata ttgcttttgc
    30901 tttagatact ggtacagcag gagacactcc aggaatgaca ccaaaagaag cagattcgat
    30961 tttaggaaaa ggcccacaga ttttgatttt tgatgcatct atgatcccgc ataaaaaatt
    31021 attgaatttt gttattgatg tagcagagga aatggatatt ccattccaat atacagtgat
    31081 ttctggcgga ggaactgatg caggacaaat gcatttgaca agagatggtg ttccgtctgt
    31141 agccattacc gttcctgttc gttatctgca ttcccataca tcagtgattc atgaagatga
    31201 ttatttgaat acagtgaaac tagtcacaga attagtgaaa cggcttgata gtgaaacagt
    31261 tgaaaaaatt cggagttatg aataatgaat aatagaatac ctatttctga atatcggaaa
    31321 aaagcacgag tttctttgga aaatcaatgg ggaatcaata cttggcttgt tttcttatct
    31381 ataatattta cgagcgtcat ccagaacttt tttgacggtt tcagtccttt tccggaagaa
    31441 agcatgcagc agcacttatt gagttttcta gtcgataatt tacttttatt cgcattcaac
    31501 tatgcattgt tttacattgc gctagtagtt gtacggggtg gcagaccaaa aagtaacctt
    31561 ttattttcag ttttccaaag aaagtatttt ggttcgatac ttggcatcaa tttgatcaat
    31621 tcagtcatca actggctact caacagttta atctttctgc ccatgttttt aatcagcgga
    31681 gtgagtactt atatgcagct gcttttcagt tcaaatgcgg tacctacggg tgtcatgcca
    31741 gaagattttc ttgatatcag ctttgtttta tcgatgatag ggatgatttt tgtttcagca
    31801 ctcatcatga gtattgttgg cggtttattc caatttgctg catggacaaa gttcgactat
    31861 cctgatttgt cggttattca atgtttgaaa tatggctggt ttttattgaa agatagaatt
    31921 ggtacgtata ttttgttgca gctgtctttt atcggctggt atttgctagg agcaatcgct
    31981 ttgttcatcg gtcttttgtg ggtcattgtt tatgtgaatg tgtcagttgc agaattttat
    32041 gaacaagcac ggattgaaaa aggaggtcca gacgcctatt ttacttagca tgtaagcagt
    32101 ttattcatca aaaaaataac ttttgtggta ggataaatct ttgaggggga atgtacgatg
    32161 aaattaactg ttttaggatg cttaggagcg tatccttata aaaatcaagg gacaacaggt
    32221 tatttgcttc aatctgacgg gttcaatttg ttgatcgatg caggtagtgc tacgctgatc
    32281 aaattacaag aacaccttga tccacttgat ctagatgctg tgatccttag ccattatcat
    32341 catgatcata ttgctgacct tggtgtatta cagtattact ggcaacttca tcctaagaga
    32401 aatccggaga cattgctttc aatttatgga cacacaaaag attccattca ctttgaagaa
    32461 ttgacgttgg aaaatgtctc aaaaggacat ccttattttg aagctgaaga attaaaaatt
    32521 ggtccttttc tgattacttt tatggaaaca atccatccag tagtatgtta cgccatgcgt
    32581 atcgtagaag aaacaacggg gaaagtattc gtatttacag gtgattcagg ttatttggaa
    32641 agtttcgctg attttgcgaa agatgctgat ttgtttctag cagataccta tctttttgaa
    32701 ggaaatgaac atcatcatgc ccatttcact tcaaaagaag ctggagaact tgcgaaatca
    32761 gctaacgtaa agaaacttgt acttacacac ctacctcagt ttggtgattt agaacaattg
    32821 aaaaatgaag cgcaaaaggc agcaggcaaa gggattgata tagaacttgc tgcagttgac
    32881 aaagtgttta acatttagga ggaagaacat gatttttgta ccaaatgaaa accacgaccc
    32941 aagaatcaat ttagcaattg aacaatattt gctgcaagaa atgcctttag atgaacctat
    33001 tttgctcttt tatatcaatg aaccttcaat catcatcggc agaaaccaaa atacgcttga
    33061 agaaatcaat cgagattatg tggaagaaaa tggcattcat gttgtccgtc gcttaagtgg
    33121 aggcggagct gtctaccatg attttggaaa cctgaacttt agttttatca tgcctgatga
    33181 tggggattca ttccgtgact ttgcgaaagt aacacagcca atcatccaag cacttcatga
    33241 attgggtgtt gctggggcgg aattgaaagg ccgaaatgat ctagtcattg atggcatgaa
    33301 attttctggc aacgcgatgt atgctaccaa cggtcggatg tttgctcatg gaacaattat
    33361 gttcgactct gatatcaatg aagtagtcaa tgcattaaaa gtaaaaaaag acaaaatcga
    33421 atcaaaagga atcaaatcga tccgttctcg tgtaacgaat atcaaaccat ttcttccaga
    33481 agaaaagcaa aaaatgacaa cagaagaatt tcgtcaagaa atcttgttga aaattttcgg
    33541 cgtagagtca gtagaagaag taaaaacgta cgaattgact gatgaagatt ggaaaaaaat
    33601 caatcgaatc tctgaggaat attatcgaaa ttgggattgg aattacggga agtctccaga
    33661 tttcaatttc tctcgccaaa aacgtttttc tatcggttcg attgaagtcc atttgaatgt
    33721 ctcagaagga atgatcaaag aagcaaaaat ctttggcgat ttcttcggac taggagatat
    33781 ctctgacgtg gaaaaaaaat tggttggaca gaaatatgat aaagcatctc tatcaaaaat
    33841 agtcagccaa attgatgtga agaaatattt tggtgcgata gaaccagaag aattgcttac
    33901 cttactttat tgaaaataaa aaatagcgga atccacatat atggattccg ctatttttta
    33961 tacaggattc gggtaatttc gagagagttg aacagtgatc cgatcaatga aagtatcttt
    34021 ttcctgcgtt agtgttcctg tgtaacgatc cgctacgtct ttcatcatca ttaagtcaaa
    34081 acgttcctga tcatctaatt cttctgtgat gcctcgacta aataggtttg tatcgtaatg
    34141 tgcactatgt tcgcaacaaa tgacgaaatg ttcctcttgt tcgtgtatcg acaaataaat
    34201 ttttcgatac agtggatttt cgatggcatg agtttctcta aaggaatgct ctaaagcgtg
    34261 gatcaaaagt tgagccagat cgtcatcgtt gataggaagt tcttcgggaa gatctgcttg
    34321 gaaggttatc tgaatattcc gtttggcagc taacttctgg taacgcgcta agataagatt
    34381 tgtcacctgg tggttgcaaa aagaacacag catttcgaaa ttttttgctt cttctaatat
    34441 cttttccaca tagtttttag cttttgtttg gtccgtatgc attaaatctt gcagattctc
    34501 catctcttgg acaaattcca ggcgaagtgt atttacttct tggatatgct gtcgaagctg
    34561 ctcataatgt tgctccaaca aatcattttt gatttttaag aaatctactt gtctccgatc
    34621 tttgtcggta tttaagatgt gatcgattag attgtagctg ataataacga ttagaatgat
    34681 aatatataaa atcgtagacc aattgatcgt tgtttgatag atacctaatg ccgtttggat
    34741 gtaaatcaag caatggataa tggctaccaa gacgatccaa ggtgtacaag ctacataaaa
    34801 acggttattc ttatatgctt cgccaatgca tgcaagtgaa gtgactaaag tgcttataac
    34861 actagcaata ttagcaatcg gcattaattc aggaagttct gcaggagtaa aagttgcata
    34921 aagcagaacg ccgataaaaa tcaaaagttg gaacgtacaa aaaattccgt accatttttt
    34981 atagtaaaac attcggctcc aatagtagca gatgatgaaa gctgacgtta agataataaa
    35041 taaatgagat aaaaaagaat gaacgaatgg ttcaaaaaga ataccactta aaatatcttc
    35101 tgatacagct tcaaatccta atgccaaagc aaagcaactt aagagaataa gtgagtattc
    35161 aagacgtttt tgtttataca tcaagtagat cgtatagaaa aaggtcccta tagcgataaa
    35221 aacagcgatt atcatcgtca atacttgcgg cactgattgt gaataaataa aactaatcaa
    35281 tggtccagtt gttcctagat aaactttcgg tggcagtcca gcatagttct gataaggaga
    35341 tgagactgta agggtcaatt tttttccgat ataatttgct ggtaaatcta tcacagccaa
    35401 tgagagtccg ggattgcttt cttcctgata atctttccgt tggtataaaa tcttttcgcc
    35461 tagatataca gtaatccatt gatggtttcc tttgattagt aaatttgctt cgtccaacgg
    35521 tttttcaagt gtcgtttcca taatgaatgt ttcgtcttta tccacggtag gaatcgtacg
    35581 agtgtacttg ctgtcaaact taaaatcagg atcatctttt gtatagaaaa cccacgaatc
    35641 ttttatttct ttcatttgat tgctgtccgc aggagaaaaa ataaaataaa agaaataagc
    35701 aattcctgtt aaaaataaca atgataatat aatgattatg ctccacttta tacgtaaata
    35761 aaaagattct tttttattat atatgttatt aaaaaaagac ataaaggtat tcctttctaa
    35821 aacttgtaat gttagggtaa acgtttttta aactaacgtc aattatttat aataaaaaat
    35881 gagataaaga tgaggaaata gaattagaaa catataatta ttaaagggaa acatttttac
    35941 agctataatt tgaaaaaaat ttatcgttat tatatgatta agaaggattg aataaagaaa
    36001 gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta taacgttgat
    36061 tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg gtttgactcc
    36121 ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc tgatatatgt
    36181 acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt atgaaaattc
    36241 aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg aagattttta
    36301 tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga gaaatattat
    36361 cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa cggcatttgc
    36421 atggattcag gggttattct ttacgattgc tttttgccta acaggaatca cagcatggaa
    36481 tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt aagaatgtta
    36541 aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca cgagaaaaca
    36601 ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg aggagtagta
    36661 tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat tttatgcgta
    36721 cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct catgtagcag
    36781 aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt ggacagcttc
    36841 agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt gtcatggcca
    36901 cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc atgatcgaga
    36961 aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg cttgaaggtc
    37021 aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt atggatagtg
    37081 caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga aaaggtggcg
    37141 ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat gaagagattc
    37201 cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt gtgatggatc
    37261 atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta atgacaaagg
    37321 aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa tcgattgaat
    37381 cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa ttaaaggata
    37441 caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt ttcaattgat
    37501 aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag tagttgggcc
    37561 aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag caatttaatt
    37621 atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg atagagcatc
    37681 cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa aaaccgttag
    37741 aaactgaggt ttctaacggt ttttctttgt tttttgtgcc aatattgttt gttttcaaag
    37801 gcaaataaaa taaaaaaaca tccttatcga gtacaattat aaggagcaaa aaaataaaac
    37861 tcatcagaaa agaggaagaa gatatgacga tactatctag aattttagtg actctagttg
    37921 caattgaatt tttttatatc atgtatatcg aaacggtgag aactgattct gacacgacaa
    37981 gtagggtttt taaaatgagt aaagaagagt taagcagaaa atctgttcaa acattgttta
    38041 agaaccaagg agtgtacaat ggactattag gagtgggact actttatgga gcttatcttt
    38101 cttccgcatc taaagaaatc acaagtatgc tattaatatc tatttttttt gttgcattat
    38161 atggcagttt gactagcgat cgttggattt tactcaaaca aggtgggcta gctctgttgg
    38221 cattgctttc tattttctta taaatataga aaaaataaga atttatctaa caggaaactt
    38281 tgtgaaaaat attactttat ctcatgaaat atgatattct aatgaatggt attttagaaa
    38341 atttcatgaa aaaggagtta gataggtgtt caaaaattat gtttcctcac taaaaaaaga
    38401 attttcaggt tatgatcttt caagatttca gaaagatctt ttggctggga tcacagtagc
    38461 tgctgtagca ttgcctttag ccttggcttt tggggtatca agcggagctg atgcggccgc
    38521 aggtttgatt acggctatca ttgccggtat cgttattggc ggtttatcag gcggttttta
    38581 tcaaatatca ggtccgacag gtgcgatggc agctatcttg atgtctattg cggcaacaaa
    38641 gggaatgcaa ggtgtattgc ttgctacttt tttagcgggt ctatttttac ttgcagcagg
    38701 acttttccga ttaggaacac tgacttcttt tatcccagca cccgtaatta cggggtttac
    38761 ttcaggtatt gctatcatta ttgcattagg tcagatcgat aatttatttg gtgttcactc
    38821 ggaaggtaca aacgttattg aaaaactaag tagttatcaa acgataggat ttccgataaa
    38881 cacagcctct ttgatcatgg gagggctagt cattttaggg atgtttatct atccaaaaaa
    38941 atgggcgaaa cgaatgccta gttcgctgct ggctatcatt ttggcaacag cagttatgct
    39001 attgttccat ttaccagtag caactgtggg taagattcca caaacattga tcagtagtaa
    39061 tcgtttgaat atgggagatt ttagcttttc tgccttgcaa caagtggcag ttccagctat
    39121 tagcattgct ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg ctggccgaat
    39181 ggcaaataag cccttagata gcaatcaaga attaatggcg caaggaattg gaaatctgtt
    39241 gcttcctttc tttggcggga ttcctgctac tgcggccatc gcccgtacaa gcgtggccat
    39301 caaatctggt gcacaaacta gattagctgg tatgatacat gcagttgtct tactgctctc
    39361 catgcttgtt tttgcgccag tgatgtcaca gattccaatg ccagcacttg caggtgtttt
    39421 gattgtgacg gcttggcgta tgaatgaatg ggaaacgatc aaggagctat ttactaataa
    39481 atattggtca gcagttctat tgtttatcct tacgatgatt tgtacagtta tctttgattt
    39541 aagtattgct atcgtgatcg gggtgatcgg cggctgtgta ttttttgttg tcaaaagcgc
    39601 tgctatcacg atttcattag aaacgatcga ttggcaaaga atggggctgc cagaaacgga
    39661 aaagctgaat aactggacag tagtgtatat tagtggtcca ctgtttttta tgtcttcaga
    39721 aaaactcaaa aataaattgg aagaactaaa tcatcacgat ggtgtcattt tctccatgcg
    39781 aggcgtacca agtattgatt tgacggcacg tgcagttttt gatgaatttc aagaaaaagc
    39841 agagcaaaga ggacaaacga ttatctatac ttccttgcag ccagaagtag aaaaacaact
    39901 ttctcacttg tgggaacata cattcacgca tcaacatcaa acagttgctc atgcgttgac
    39961 agctttacat gcgaaatata ctgcaattag ccattaaaac aatgaaaaag aacagacaag
    40021 actgtaaact gaagatttta tggtcttgtc tgttcttttt aatattgctg taaaagtgaa
    40081 gctagtactt gccagtcttg atggataaca ggtacaaggg agcgattgta gaaaatagct
    40141 gctggatgaa aaagtggaag aattcgatag tttttttctg accattcgta ggcatccttt
    40201 tgttctgtta attgtaagac aggccctgta tagagttgac catgattttt ggtaaccgta
    40261 tattctttgc caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat taattttggc
    40321 tggaccttca tcagttcgta atccaatatt ggtgcatgcg caaatacttc ggaacgagta
    40381 ggtgtccgat ttggataaac agtttctgac tgttgtgtcc gtttattgat ccgatgagtc
    40441 acgcgatacg ggcggctcct tacagcactg gtgatataca cctcttctcg tgttaagcca
    40501 gttgaagaaa gtgcctgcat caattctttt ccagcttgac cgctaaaagg aacatgcgta
    40561 tcaatctctg ttttccctgg ggcttctccc acgagcatca gtttaggatg aagaggtcct
    40621 tgcccagcga taaatccttc tacaggacgg ccgttcattc ttaaagaagc ttcttgtatc
    40681 agttcttttg ggtattccat ttatgctcct cctttttctt ttattataag aataaaagaa
    40741 acacaatgcg actattttat ttggtagaac tgtgaggata gaaaagcaga agtattgctt
    40801 gaatttttgt tttacttttt gattttaaat ttagttgact aacggttgct gttctggtaa
    40861 gctagtactg ttgtaattgt ggactccaca gctacaaccg ctcagaacaa gtaataagca
    40921 cagcatatgc tgtcacttcg gatggcgagt ctaagtatat cagaaggagg tgctttatag
    40981 catgtacgca attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg gacaagcaat
    41041 ctatgttgaa aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg aagttatctt
    41101 agtaggcgga gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa ctgttgaagg
    41161 tactgttgaa aaacacggca aacaaaagaa agtcgttact ttcaaataca aacctaaaaa
    41221 acattcacac cgtaaacaag gtcatcgtca accatataca aaagtggtta tcgacgcgat
    41281 caacgcttaa tagcgtttga gaaagaaggc ctatatatga tcaaaggaac atttaagcga
    41341 aatgacgcag gtcagatcgt ttcattcact ttgaccgggc atgctgatgc tggtccttat
    41401 ggaagtgata tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt caacgggatt
    41461 gcctcattag ccggttttga gccgattgtt gaaatgaatg aagaagaagg cggttatctt
    41521 tataccgaag tcacttcagg aatgacacaa gaacaaaaca atattgctga gattctatta
    41581 gaaaatcttt tattaggatt acaatcgata gaagctgaaa actcagaata tatccaaatt
    41641 aaaacaatta atgataaata ggaggtgcag accatgttgt tatctatgaa tctacaatta
    41701 tttgcccaca aaaaaggtgg cggttctaca tctaacggcc gtgactcaga atcaaaacgt
    41761 ctaggtgcta aacgtgctga tggacaaaca gttacaggtg gatcaattct ttaccgtcaa
    41821 cgcggtacaa aaatctatcc aggtgtaaac gtgggtatcg gtggagacga cactttattt
    41881 gcaaaagttg atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa acaagtgtct
    41941 gtttatccag tagctcaaga agcttaattg aatcttatga ttaaagaggt tgtgacaaga
    42001 cttttgtcac agc
//
LOCUS       DAPBBR010000023        40815 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPBBR010000023 DAPBBR010000000
VERSION     DAPBBR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.023"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            23..646
                     /locus_tag="RD488_001317"
     CDS             23..646
                     /locus_tag="RD488_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657401.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="RD488_001318"
     CDS             1096..2145
                     /locus_tag="RD488_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7657402.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="RD488_001319"
     CDS             2142..3023
                     /locus_tag="RD488_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657403.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="RD488_001320"
     CDS             3026..3796
                     /locus_tag="RD488_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7657404.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="RD488_001321"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="RD488_001321"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDT7657405.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="RD488_001322"
     CDS             5107..6270
                     /locus_tag="RD488_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7657406.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="RD488_001323"
     CDS             6387..6797
                     /locus_tag="RD488_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7657407.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="RD488_001324"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="RD488_001324"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7657408.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="RD488_001325"
     CDS             9370..9654
                     /locus_tag="RD488_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657409.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="RD488_001326"
     CDS             9814..10050
                     /locus_tag="RD488_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7657410.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="RD488_001327"
     CDS             10047..10445
                     /locus_tag="RD488_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDT7657411.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="RD488_001328"
     CDS             complement(11112..12056)
                     /locus_tag="RD488_001328"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7657412.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="RD488_001329"
     CDS             complement(12352..13296)
                     /locus_tag="RD488_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657413.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="RD488_001330"
     CDS             13517..14731
                     /locus_tag="RD488_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7657414.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="RD488_001331"
     CDS             14753..16768
                     /locus_tag="RD488_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HDT7657415.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="RD488_001332"
     CDS             complement(16851..18224)
                     /locus_tag="RD488_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7657416.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="RD488_001333"
     CDS             complement(18250..18534)
                     /locus_tag="RD488_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7657417.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="RD488_001334"
     CDS             complement(18536..20551)
                     /locus_tag="RD488_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7657418.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="RD488_001335"
     CDS             complement(20730..21035)
                     /locus_tag="RD488_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HDT7657419.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="RD488_001336"
     CDS             complement(21124..22155)
                     /locus_tag="RD488_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7657420.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="RD488_001337"
     CDS             22362..23237
                     /locus_tag="RD488_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7657421.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="RD488_001338"
     CDS             complement(23389..24231)
                     /locus_tag="RD488_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7657422.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="RD488_001339"
     CDS             complement(24323..26200)
                     /locus_tag="RD488_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7657423.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="RD488_001340"
     CDS             complement(26197..27618)
                     /locus_tag="RD488_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7657424.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="RD488_001341"
     CDS             complement(27621..31010)
                     /locus_tag="RD488_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDT7657425.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="RD488_001342"
     CDS             31267..32658
                     /locus_tag="RD488_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657426.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="RD488_001343"
     CDS             complement(32731..33378)
                     /locus_tag="RD488_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7657427.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="RD488_001344"
     CDS             complement(33386..34072)
                     /locus_tag="RD488_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657428.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="RD488_001345"
     CDS             complement(34078..35151)
                     /locus_tag="RD488_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657429.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="RD488_001346"
     CDS             35373..36047
                     /locus_tag="RD488_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7657430.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="RD488_001347"
     CDS             36052..37392
                     /locus_tag="RD488_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7657431.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="RD488_001348"
     CDS             complement(37541..38527)
                     /locus_tag="RD488_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HDT7657432.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="RD488_001349"
     CDS             39251..40282
                     /locus_tag="RD488_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7657433.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..>40815
                     /locus_tag="RD488_001350"
     CDS             40391..>40815
                     /locus_tag="RD488_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDT7657434.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        12669 a         7414 c         7662 g        13070 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggtgccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga aggaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcc
//
LOCUS       DAPBBR010000024        39012 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPBBR010000024 DAPBBR010000000
VERSION     DAPBBR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.024"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            5..304
                     /locus_tag="RD488_001351"
     CDS             5..304
                     /locus_tag="RD488_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7657435.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            377..1738
                     /locus_tag="RD488_001352"
     CDS             377..1738
                     /locus_tag="RD488_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7657436.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1760..2020
                     /locus_tag="RD488_001353"
     CDS             1760..2020
                     /locus_tag="RD488_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657437.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2034..2786
                     /locus_tag="RD488_001354"
     CDS             2034..2786
                     /locus_tag="RD488_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDT7657438.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2880..3485)
                     /locus_tag="RD488_001355"
     CDS             complement(2880..3485)
                     /locus_tag="RD488_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7657439.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3538..4512)
                     /locus_tag="RD488_001356"
     CDS             complement(3538..4512)
                     /locus_tag="RD488_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDT7657440.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4890..5609)
                     /locus_tag="RD488_001357"
     CDS             complement(4890..5609)
                     /locus_tag="RD488_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7657441.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5736..7007)
                     /gene="celB"
                     /locus_tag="RD488_001358"
     CDS             complement(5736..7007)
                     /gene="celB"
                     /locus_tag="RD488_001358"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7657442.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7160..8557
                     /locus_tag="RD488_001359"
     CDS             7160..8557
                     /locus_tag="RD488_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7657443.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDFFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8638..9078
                     /locus_tag="RD488_001360"
     CDS             8638..9078
                     /locus_tag="RD488_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7657444.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9226..9552
                     /locus_tag="RD488_001361"
     CDS             9226..9552
                     /locus_tag="RD488_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7657445.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9553..10302
                     /locus_tag="RD488_001362"
     CDS             9553..10302
                     /locus_tag="RD488_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657446.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10382..10837)
                     /locus_tag="RD488_001363"
     CDS             complement(10382..10837)
                     /locus_tag="RD488_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7657447.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11264..11539)
                     /locus_tag="RD488_001364"
     CDS             complement(11264..11539)
                     /locus_tag="RD488_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657448.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11833..12648
                     /gene="thiD"
                     /locus_tag="RD488_001365"
     CDS             11833..12648
                     /gene="thiD"
                     /locus_tag="RD488_001365"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDT7657449.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12977..14428)
                     /gene="cls"
                     /locus_tag="RD488_001366"
     CDS             complement(12977..14428)
                     /gene="cls"
                     /locus_tag="RD488_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7657450.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14769..17435
                     /locus_tag="RD488_001367"
     CDS             14769..17435
                     /locus_tag="RD488_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7657451.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17799..18551
                     /locus_tag="RD488_001368"
     CDS             17799..18551
                     /locus_tag="RD488_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7657452.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18573..19727)
                     /locus_tag="RD488_001369"
     CDS             complement(18573..19727)
                     /locus_tag="RD488_001369"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDT7657453.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19912..22353
                     /locus_tag="RD488_001370"
     CDS             19912..22353
                     /locus_tag="RD488_001370"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDT7657454.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22683..23387)
                     /locus_tag="RD488_001371"
     CDS             complement(22683..23387)
                     /locus_tag="RD488_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657455.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23574..23819)
                     /locus_tag="RD488_001372"
     CDS             complement(23574..23819)
                     /locus_tag="RD488_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657456.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23836..24687)
                     /locus_tag="RD488_001373"
     CDS             complement(23836..24687)
                     /locus_tag="RD488_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7657457.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24853..25857
                     /locus_tag="RD488_001374"
     CDS             24853..25857
                     /locus_tag="RD488_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDT7657458.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26098..26454)
                     /locus_tag="RD488_001375"
     CDS             complement(26098..26454)
                     /locus_tag="RD488_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7657459.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26822..28009
                     /gene="tuf"
                     /locus_tag="RD488_001376"
     CDS             26822..28009
                     /gene="tuf"
                     /locus_tag="RD488_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7657460.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="RD488_001377"
     CDS             complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="RD488_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7657461.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30814..31575)
                     /locus_tag="RD488_001378"
     CDS             complement(30814..31575)
                     /locus_tag="RD488_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7657462.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31742..32374
                     /locus_tag="RD488_001379"
     CDS             31742..32374
                     /locus_tag="RD488_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HDT7657463.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            32433..33293
                     /locus_tag="RD488_001380"
     CDS             32433..33293
                     /locus_tag="RD488_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDT7657464.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33478..35793
                     /locus_tag="RD488_001381"
     CDS             33478..35793
                     /locus_tag="RD488_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7657465.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35975..37816
                     /locus_tag="RD488_001382"
     CDS             35975..37816
                     /locus_tag="RD488_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDT7657466.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37840..38949
                     /gene="rpoD"
                     /locus_tag="RD488_001383"
     CDS             37840..38949
                     /gene="rpoD"
                     /locus_tag="RD488_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDT7657467.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT        12555 a         6864 c         8087 g        11506 t
ORIGIN      
        1 aaaaatgaaa aatcggttaa ttgtcgcatg tggaagtgga gtagcaacga gtcagacaat
       61 cgctagtaag atccaaagta tgttagaaga tgacggcatc gcatttcctg tagaagcagt
      121 tgattacaaa tcgattcaaa atgagcttct aactgctgga atctatgtgt atgtcgcaca
      181 acctgatgag gaagtacttg aacaagcaaa agatttgggt attgaagtat ttccaggaat
      241 tccattttta actggaatgg gtgtagaacc tatttatgac agtatcaaag agttagtaca
      301 gtaaaggagg attgttggat aaaaaagttg gttcatagtt ttatttacta tatttagaaa
      361 gaaagaaggt ttatttatgg aagttttcca aaccattatc aattatgttt tgaacttagg
      421 atcagccatt tttgttcccc tgattatttt gatacttgga ttgttggcag ggatgaaatt
      481 aaaaaaagca ttcatgtctg ctttgacttt agggattgct tttagcggaa tgtctatggt
      541 cattggctat atgtctaacg cagtaagtcc agcatcagaa gcattggcta aaaatacggg
      601 aatcagtttg cctgcacttg atcttgggtg gacaggtgca gcaagcatca catggtcgtg
      661 gagttatgct tttatatttt ttgcagtaac gattggggtc aattttgtac tgttactttt
      721 taattggacg aagacgttaa atgttgatat gtggaatgtt tgggggaaag ctttaactgc
      781 ttatttagtt tattatgttt ccggtagttt ggctgcaggc tttcttactg caatggtcca
      841 agttatattg gaattaaagc ttggtgatat gtttcaaaaa catatacaag atctcacagg
      901 gattccatta gtaacagtga ctcattttat gacatctgcc gctgtcttgt tgctgccttt
      961 caatatgatc atggataaaa ttcctgcttt aaataaacga gcggatacga atgcattgaa
     1021 gaagaaaatt gggatcttct ctgaaaactc tgtaatggga ttcattattg gattggggct
     1081 tggctttgct gctgcgtatg gcgtttcagg ttctcttaat ctagcgatcc aaacagctac
     1141 agcattaagt ttgtttccta tgatctctaa aatgttcatg caatctttgt ctcctctagc
     1201 agacgctatg tcagaattta tgaaaaagcg gtttaaggat cgtgaagtat atatcggatt
     1261 ggactggccg atattagctg gtcgttcaga aatttgggtt actgctattt tacttgttcc
     1321 tgtgtttatt ggttatgcca ttattttgcc aggaaaccaa gtattgccat tagcagggat
     1381 tatcaactat tcgattgcgg tcggcggatt acttttaaca ggaggaaact tggctcgtat
     1441 gctgatcttg ggaatcatca ctatgcctat ttatttgtac ggggccactt accttgcgcc
     1501 aatactcagt gatttagcag aaaaaagcgg agcagtcgag ggaatcaaga aaggacagtt
     1561 gatcacatgg tcatccatag aagggccgga gttcagggtt ttatttgcgg aggcatttaa
     1621 taggaatatt ctcgctattg taggatgcgt gatttttcta ggactgtttg ttctacttta
     1681 taaatatatg ataaaagcga aagtaccgag tgaacgttat gctgaactac aaaaatagca
     1741 ttgaaatggt gggaaagtaa tgaaaagaga agagacagat aaaataaaat ggacagtcgc
     1801 tctttgtggt acacttctgc tatttctata tggactcttt actcagaata tcatcatcaa
     1861 tctattggtc atttttttcg cactagtgat ctataaatat ggaaatcacg ttttattcag
     1921 agagtacgat gaaaaaagaa aacggaaaat agaagaatca atgaaaataa aagaagctac
     1981 caaagaaata ttgagagaaa aaagttttat aaaaagataa tggaggggtc attatgtcag
     2041 atggacgtat gttatttgag agagaacgac aggacatggc acgtatcgta agagtgattt
     2101 tcgaaaggaa aaacacaaat gtcgcaggag ggaatttttc ctttaaaacc actgatgatc
     2161 aagggaaaga ctacatcatc atgacgccga ccatgatgtc agaagcctat ctaggagaga
     2221 tttctcctgc acaggttcta gtagtagaac caagaacgcg tagaatcgtt gacggagtcg
     2281 gtcatttaac tcgtgaaatc aatatgcatg aagcgatgta tgagactaat ccagctatca
     2341 aagctgtcct acatgctcat gcgcctaatg caatgttctg ggcgactact gggttgccta
     2401 tgcctaattt gacagaagcc acagctaaag taaaagagat tcctgtcatg gactttgagc
     2461 ctaattgctc tgaagaactt gctgaattga caagcgacta tgtaaaaaaa cagcatctcg
     2521 aattaccgca tatgttgctg ctcaactctc atggcgtatt gatcaacaca ggtggagaat
     2581 caggaatcga agctatccat aaagcactgc aaatccttga tacagttgaa tggaatgcag
     2641 aaattgccta caagcagacg atttttcaag cattagggat tactgacggt ttttattcaa
     2701 aaggtgagaa aatcggggga ttggaagagt tgaaacataa aacggctatt tataataaat
     2761 ctgttattgc agctggtgga gactaaccta tctgacacaa aaaactacga ctttcacaaa
     2821 atctgatcca gatcgatatc tgcttcaggt tgtattatgt aagtcgtagt tcttttcttt
     2881 tatttagtta agaggtggtc tgtccattcc ctcgcttgct tgatttcgtc catcgtcaac
     2941 tgatgacctg ttacagttag ctgaatagtc acatttgctt ggcgtgtttc gaattgatcg
     3001 gccaattctt taaaggaagc aggggaaacg attggatcgt tatcaccata agaaatccag
     3061 acggttttat cctctaatgt ggaacggctt tgatgaacac ctagagacat cggatggaaa
     3121 aacaaccctt tatttagctc ggtctcacgc tccaataata aatgagcagc gatgtttgcg
     3181 ccatttgaat agccgacaag cagccagtca cttaacggta tcagttcttt ttcgctgatt
     3241 tctttgattt tttcatggag tttatctgtt tctttttcca aactgtccag gtcgaattga
     3301 ttcaatccat tacgcttgaa aaaacgattc atcccatctt cttggaccgt gccacgaaaa
     3361 gaaagcaatg tactgtttgg tgcaagaaag tgagcgatat ccagtaaaga atgttcatcg
     3421 ccacctgtgc catgaagtaa gatcaaatgc ttgccacttg ttcctttttc aaaaatgtag
     3481 gtcattttgt tccctctttt ctgtttctat agatgcaaat gaagtagcat gaagagatta
     3541 ttcacgtttt ttatttgcat cacttgtatc gaaaggacgg acataagctt caatggcttc
     3601 acgacgttct tctaagaatg gaggaagaga tagtttttct cctgctgatt ctgctggttc
     3661 atcttcaagg aatccaggac catcagttgc taattcaaac agtacgtgat gagcggctag
     3721 gaagtactca gattggaaat agaaacgatc gacgaaacca gaatttggca attcaatctt
     3781 attgattact tgaatccagt attccaatgc ttctttgtct gctacacgca atgctaagtg
     3841 atggatattt ccaaatcctt cgattgcttt tggcaagtct gtccgatgtt caataatgat
     3901 gcttgcacca tttccccctt caccgatttc aaataagtag aaatctcctg aatggtctgt
     3961 ttctttgaat cctaagattt tttcaagaat caagcggata tgctctaatt gactgacacg
     4021 gacaaagaca ggtccaagtc ctgtgatcgc aaactctgtc ggtacattgc tgtttttcca
     4081 aggaatgcca gctgctacac cttgattgtt ttcgtcagag atcaattgat aatactgatt
     4141 atcgaaatct tcaaattcga tatatttttt gccgaaacgt tcattgattg ctgaatgagt
     4201 aacgtcatat ttttcaaaac gttccaacca aaagtctaat gctgcgtcac ttggcacacg
     4261 gaaagaagca cgagagatcg tatctgttcc tttttttcct tttggctgat ttggaaaatc
     4321 aaagaaagtc atatctgttc ctggcgcacc agtatcgtct gtaaagtaaa gatggtaagt
     4381 ttcgatgtca tcttggttaa ctgttttttt gattaagcgc attcctaaaa tatctgtaaa
     4441 aaagcggtag atttttgtag cgctagatgt cattgctgtg acgtggtgaa ttcctctgat
     4501 ttgtgtatcc atgataaatt tcctcctgtt aacttacaaa aagtaagtag ttgatttaga
     4561 catagtatag agggtgcatc tctattttgc aattaatttg tcttctaaag tatcaggaag
     4621 gaatcaagaa tggaaaagag gagggacgga tcaataaaat aaaaagactt acgactagct
     4681 gtatcgattt caaaaaaact agctttaaaa agctaacttt agaatcatta cgggtggtca
     4741 taagtctttt tatgctgagt tattttttca tttttgagct aatgcttagg atagaataga
     4801 atgttgattt cacgatctct tcttgttact tgaaactgct taccactgtc acgatctctt
     4861 ggtaaacggc tttttcacaa cctctttggt taagttgaac gcacatccag cacagaatag
     4921 ttccgaacat caaatcggtt tcggctggaa gaatattcaa tcggctgtcc atctttgaga
     4981 tagacgactt gctgaacttc cagtacagga tcgttttctg cacagttcaa atattgctga
     5041 tcatattcat cacttttatc tgcagaaata gcacgataag cccctgcaaa atggacattc
     5101 aattcttgat gaagatgatc atagatagag gctaacaaat gttctttttt taaacccggc
     5161 acaagatgga ctggcataaa ggtatgctct aaaacatatg gctcgccatc taagatcctt
     5221 aaccggtgaa tattgtagac aggttgctcg gcatcgatca tcaatcgttc ttggatatat
     5281 tgattaggga attcaacatc aaaatgaatg atttgactct tcaaagaacg atgtctgcgt
     5341 ttcatttgga gactcaaacc ttcatactcg ttagcgggcg atgtgtcttt ttgcataaat
     5401 ggatgattca agattttcgt tcctgatcct cgctgcgaat agacaagtcc ttccattgct
     5461 aagatattga tggctttttt gattgtcatc cggctcgcac caaattcttt taccaagtcg
     5521 acttgattag gcaaaaaact atcgagagga tactcttttg aacggatacg ttctcttaaa
     5581 atatttgcga tttcttcgta ttttggcacg ttattcacct cttctagagt ataacgaaag
     5641 attatgcttc cgacaactcg aagtagcatc tggaacattg tttattcgaa aaaagaggtc
     5701 atgacaagtt tttgtcacaa ccccttaatg atctattaag caatatctaa atctggttgt
     5761 ttatctagta ctttcaggaa tgggtaccag ataaaggcaa cgatgacaaa gtcgatgact
     5821 tgcagcatac caccaagcca tgaatttgtt gctaagacac cgcttgcaat gattggcaca
     5881 gtccatggaa cagagacgcc agttggtgca gggacaagtc cagcagccat taccaaataa
     5941 ttgaacgtcg ttacgattag aggtgccaca acccaaggaa taaggattgt tgcattcaat
     6001 acgatcggta gaccgaagat cgctggttca tttacattga aaataccagg tgctaaagct
     6061 aatcgtccaa catcacgata ctgtttcttt ttaagaacaa aggccatcaa taaaacgaca
     6121 gctaaagtca ttccagagcc accaatacca acagtgaagg tttccatgaa tggttttgtg
     6181 atgatgtgtg gtaattcttt tccatgttga taagcttcta agttatcaag catcagtgta
     6241 ttccaaatcg ggtccattac agagttgacg atgatttgtc cgtgaagtcc gaagaaccat
     6301 aagaattgga caaagaacaa agcaatcaat gttgcaggta aactacttcc caaaccagtt
     6361 aatggttttt ggatcacttc ataaacgacg tcatgtaagt tagcattgaa aataccagtc
     6421 atcacagcat tgattactaa gaaaatagtt agtgtcacta cagcagggat caaagcggca
     6481 aatgattttg ttactgcagg cggaactcca tcaggcattt tgatctgcca gccgcgtttc
     6541 gtgattctgc agtagatttc tccagccaag aaagcagcga tcattccaat gaacattcct
     6601 tttgcgccaa gacgatcaag tgaaagcaca ccagtcacat cttcaccgcc agcggttttc
     6661 attgcaaaag gcgtaagaat caagaagctg gcaaaagaca cggcaccacc gaaaatacct
     6721 tcaacgtcat aagattttga taaataatag ccgataccaa aagtaacaaa aaccgacatg
     6781 atgctcattg ttgcattttg cccattaccg aataaattcg ataaagttcc ctttgttgcg
     6841 tcactgaaaa aaggcaagtt attgataacg acaacgatcg aaccgaacat cgttaaaggg
     6901 aaggaaagca tgaaagcatc ccgcagcact gtaaggtaac gattttgccc taataaatta
     6961 gctaagggca tgattttctc agaaagcttg tccataaaac cgttcatttt tattcacctc
     7021 aaatttattt gcaatcgatt acatacaaag tataacgcca aaaaaattaa atgtctagtc
     7081 attttcataa aaagtattga tttatttttt agggttcgtt atgattacgg tatcaagaaa
     7141 aaagagagga agtaaaaaaa tgaaaaccta cacattccca gaaaattttt ggtggggttc
     7201 tgctgctagc ggaccgcaaa cagaaggaag agtaagtgat gatggtaaag gagaaaatat
     7261 ttgggatcat tggtatgaat tagagcctga aaaattcttc gatcaagtag gacctgaaaa
     7321 aacttcgcaa gtttacacaa aatacaaaga agatgttcag ttaatgaaag aaactggcca
     7381 taacacattt cgtacatcta tccaatggag tcatttgatt ccagaaggga caggtgaaat
     7441 caatcaaaaa gctgtttctt tttatcgaga tttttttact gaattgctgg ataatggtat
     7501 tgaacctttt gtgaaccttt accatttcga tatgccacta ccactgcaag aaaaaggcgg
     7561 atggttatca agagaaacgg tcgacgctta tgtttcttat gcagcagcgt gctttgaact
     7621 gtttggagat ctggtcaaaa aatggtttac tcataatgaa ccaatcgtac ctgtagaagg
     7681 aggctacttg tatcaattcc actatccaaa tcatatcaat atgaaagaag cggtccaagt
     7741 aggctatcat gagaatctag caagcgcaaa ggtaatcaaa gcctaccatg aaggcggaca
     7801 tgatggtgag atcggaatca tcttgaatct gacaccaagc tatccgagag atgaaacgaa
     7861 cccagaagat gtaaaagcgg cgaagatcgc tgacgcattc ttcaaccgat cattccttga
     7921 ccctgcagtg aaaggagagt ttccacaaga gttgatcgaa attgtcaaag aattggctat
     7981 aatgccagag atccatgaag gagacctaga actcatccgt gaaaacacga ttgacctgct
     8041 aggaatcaat tactatcagc ctcgtcgaat caaagcaaaa gaaactccaa tcaatcacga
     8101 acatagcccc atgccagatg attattttga taattacgac atgcccaata aaaaaatgaa
     8161 tccatatcgt ggatgggaaa tttacgaaaa aggaatctat gatattttaa cgaatacaag
     8221 agaaaactat ggtaatatca aatgctatat ttctgaaaat gggatggggg tcgaaggaga
     8281 agaacgattt gttaacagcg aaggaattat tgaagatgat taccggatcg agtttgttac
     8341 ggatcatttg aaatacgtcc atcaagcaat ccaagaagga accaattgtg tgggttacca
     8401 catgtggaca tgtatggaca actggtcttg gacaaatgct tataagaatc gctatggctt
     8461 tatcgctgtt gatttggcac aagacggtaa acggacgatc aaaaaatcag gtcgctggtt
     8521 taaaacggtc tctgaaaaaa acggatttga tgcctgatat tttttgataa aacgttcaca
     8581 aaatgtttgt tctaacactg taatcgtgct acactaacag tgaaggaggc gtttacaatg
     8641 gtagatactt atcgtaatat tttagtagca attgatggtt ctgaaaaggc agaaaaagca
     8701 tttcttgagg caatcacgat tgccaaacga aatcaggcaa cgttgcacat cctgtatgtc
     8761 aatgaagtaa caggcaatta ctttggtgat tttgcatttg ttacaacaag ccttcaggaa
     8821 gaattggatg aggttgcgga aaaccagatg aaagaacatc gaaacttggc aattgaaaaa
     8881 ggcctgacag atatcgagac atatgttctt tacggttatc caaagacact gattgctaat
     8941 ttccatgaat cgaaagaacc aatcgatctg attgtcatgg gggcgacagg tctgaatgcg
     9001 gtagaacgtg cactagtagg ttccactact tcctatgtag tcaaccacgc atcatgtaac
     9061 gtcatggttg taaaataaat aaattaaggg aacagaaagc aaaaaagcat aacgcttctt
     9121 ttgctttctg ttccttttat ttttttgtaa aaaattactt tacctgatga agtaatcatg
     9181 ctattctaat tacaacgaca gatggagtaa tatggaggaa agaaaatgat ttcaagtgat
     9241 ggaatacgcg gatacaatga tgcgattatt ttatcgatcc ttaacaaaaa cgattcttat
     9301 ggatatgaaa tttctaaaac gattcgtgag aggacaaatg attcctatgt gatcaaagag
     9361 acaacacttt actccgtttt tgcccgttta gaaaagaatc aactgattgt ttcgtatcct
     9421 ggagaagtga ctcatggaaa aaagcggaca tattataaaa tcactgaaat agggcgtaat
     9481 cttttagaag aaaaaaagca agagtggctg acgacgaaag acgtagtcga tcaatttttg
     9541 gagggaaatt aaatggatac aatccgtaat tatttagaca gtctttttat cggagtacct
     9601 caaagtaccg agatagataa gctgaaaact gatttgttgg caaatatgga agaccattat
     9661 catgaattga tgggagaagg aaaaaatgaa caggaggcca tcggtacagt aatttcgaca
     9721 tttggttcaa tcgatgaatt attagaagaa ctagatgtcg aaaaaaaaca tcaagctgac
     9781 gagacggaaa caaacacagc ttctatttat ttaagcgaag cagaaaacta ctggaaagaa
     9841 tacagagcgg caagtctcca agtggcatca ggtgttctat tcattagctt atcttttgca
     9901 agttttcttt tcttttgttc agcaggatat gtgttcatgg gtatttcttg tctgattttc
     9961 ggtatagcat tagctgtcgg tttttttatt gcttctggta tgaaaatcac acgtttaaat
    10021 cactttttgc accatcggaa aatacctgaa aaagtattag cagaagcaaa agaaaaagaa
    10081 gaagagtatc agcgaagttt tggcttctca ctgattgcag gaattggatt atgtattttt
    10141 tcacttttcc cacttttggc ttctttaatg tggtatatgg atggtagtat cggtgcctct
    10201 atattttttg ttacggtagg aacgggtgtc ttcttgatca tttatggcag tctagtccgt
    10261 cattcttatc gtcaattcac tcaaagcgct tattactggt gaatgtattc agatttgtaa
    10321 aaatattcta tttatccggc gtagaaaaaa agactgtgac acgcttttgt cacagtcttt
    10381 tttatatata ataatttaaa aattcatcat ctaaatccgt agaattttct agattgctta
    10441 cccatgtaaa atcgttatag acagatttca gttgacttct gcgccattgt acagggataa
    10501 aaagacgcat gctatcttca ttgaatccga ctaataattt ctttccgtca gtaatgatgg
    10561 gacgttgtaa caaagtaaaa tgcgagacga tcagatcgac aagctctgag gtcgtacatt
    10621 ggtcgatttg gtctttcaaa tttttataat caatcgagcg tttagctaat agatcgtcaa
    10681 atccgttttc tgttaatgac aataaataaa atatctcttt ccttgttaaa ggctgtttag
    10741 gtgtgaaaat tcgttctctg taaggcattt gatggtcttt cagccagttt gccatcagat
    10801 ggtaactatg tgtgcgagaa gaatagatcg taagcataaa aaaactcctt aaatagtcca
    10861 ttaatttgtt agatctgttg agataaataa taggtaagga gctgtgcata agcattgatc
    10921 aaaacaaccc aaacatcatt agaaataact ttctaaagtc ttaaacttgc gacgagaaac
    10981 aactagacta atagaaaaaa tgtcttagcc atttggcttc ctgtttgttt ttttgcttat
    11041 gctgcagctc ctcgggaaag ggttctaaca atttgaagaa ggttgatgat tgatctagtt
    11101 taaattgtgt gaaatttgaa atctggtgtt tttactagat gaatcaccta acaactatga
    11161 ttataactta tagaacttct gttttgcatt cggttttgtt atagttgtta taaagtttta
    11221 ttttattaca gaacattttt aattaataaa gaacagttag aagttaaaat tgctgattca
    11281 catagagttt atgacttctt ggaaattctt tttcaatcag ttttttcatc tgtttatgaa
    11341 attctttttt ttcagtaaac ataaaggttt gggtatcgta accttcttca tgtaggaaat
    11401 agattattcc tttttctgtg ttttgcgtat aagcttttat actcctgtct tttttgaaag
    11461 aacagatcgt atagccatct atttggtctg gtagtcgttt gattttcttc aaaatgactt
    11521 ttttatcctc aagtttcatt tttttcacct gactttattt ttttcatatg gaaatcatag
    11581 cgcctttggt tatatgaaaa caagaaggat actgaaatat atataaatca aatagtggtt
    11641 atttattatt agaatagcga atacaaataa acgaccacta ttttctgatt tattgcaaat
    11701 gttttttcaa ataaatttga ttaccaagaa aaggtagtgg tatatttact gagggatact
    11761 ttgaaaaaca tatgatagaa acagtaacag tattatgaaa aatcttttta taaaaatgga
    11821 ggaatcgatt tgatggaaga tcagtatgta caagcaatga cgatcgcagg atcagatagc
    11881 gatggaagcg cagggatgca agcagatatg catacattct ttacaagaaa tgtttacggt
    11941 gtttctgtca tgaccgcatg tgttgcaggt aattcttacg gaatcggagc aagtgtgaca
    12001 ttgccaacag attttatcga caaagaattt gaactgattg cgaaggactt tcaaatacgt
    12061 gcagctaaaa caggtatgct agcagattca aagttgattg agacagttgt aaaaaattac
    12121 caaaaatatg attttggacc attagtcgtg gatcccgtaa tcgtaacgaa acatggaaat
    12181 cttttactag aagaatctgc tttgcaaagc ttgaaagaaa agcttgtccc tttggccgaa
    12241 gtactgacac ctaattttta tgaagcagaa aagctgactg gacggacatt agcagctgaa
    12301 gaagattttg tgcaagcagc aaaagaactg caagatatgg gtgcaaaaaa cgttatgatc
    12361 aaaggacatc atgctaaaaa tgcgcagcaa gaaacagtca atgactacgt attgttcgaa
    12421 tcaggaaaat cattttggtt aaatgcacca ttttatccta ccgaccggat caacggaact
    12481 ggcgattcgc tatctgcatg tattgcagct gagttagcga aaggaaaaac agttgaacaa
    12541 gcgatccgat tggcaaaaga ctatgtaaac cgtgcaattc gtgaagaaat aaatgtaggg
    12601 cacaaatatg gccccatcaa tcattgggca gctggtgaat tagagtaaaa gaaagaagtt
    12661 gtgaaaaagt tgccctgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt
    12721 ttttaacttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    12781 ggtcgtgagc ctgccgtcca gctccgagtc acaaggaaca agttcaaaaa acagcttctc
    12841 atgtttgttg aatattgtga cttgtgaccg aggagttggc aggagaacac cgtttgttcg
    12901 gaagaaggga ctgtgacaag atttttgtca cagtcccttt aatcttagta tatttttctc
    12961 tacttgaata aaaaaattat aggattggag aaaataatcg agaaatttgt tgcttgaata
    13021 atagccagtt agacatttcc ttgactgttt cagttgtcat ggatgaacaa tgtgtctcat
    13081 cttctttgaa ctgagtagca agttcttcta aaaactcagg atcgtaaatg acagcacttg
    13141 tttcaaaatt caatcggtag ctacgaatat cttgatttgc tgaacctacc atgcagattt
    13201 catcatccat tatcaatgtt tttgcatgga ggaagccgtt ctcatagaca aggatttgta
    13261 cattttcctt gatcagctgc cgagcataat attgtgttgc tcgataaata aaaggatgat
    13321 ccggtttgtt gggaatcatg attttcacat ctacaccaga ggcagttgcg atttttaaag
    13381 cagcaatgac actttcatca ggaacaaggt aaggtgtctg tatccaaaca cgttttttag
    13441 cagaagtaat caatttgata aatgaaagct tgatttgttc cctttcgtta ttcggtccgc
    13501 ttgaaacaag ctggatggat gtatcagcaa gcttagattc atctcgatct gcttttttaa
    13561 agaaataatt caaatgatag ccgacctttt tttcttcagg taccgagacg ttccagtctg
    13621 ttaagaagcg aagctggagc aaagaagaag cggcaccgaa aatccgtata tgcgtatcgc
    13681 gccaatagcc gaattttttt gttgtattta catattgatt ggcaatattg aaaccaccgg
    13741 tataactaat ctttccatcg atcacaacga tttttcggtg atcatggtaa ttcaatcgga
    13801 aacgaagtaa tgccctttgt gaggtaacaa atgtatggac atgtccacca tttttgatta
    13861 gacgattgaa atcttttgct tttgtgccat gagagccaaa tgcatcatat aatattcgaa
    13921 cttccacgcc ttctgcggct ttttcttcta aaacatgtaa gacttgctgg ccgatattat
    13981 ctgtcacaaa tgcgtaatat tcgatatgga tcgaatgttt ggcttttttt agatcttgaa
    14041 gcagtgaatc caatttctct tgtccgtctg tgagaagagt gacagaattc attcttgtca
    14101 gcggcatacg atttaatgaa gagaagaagt caacaaattg ctgtttgtct ttatcgccca
    14161 tgtcaggatc gtaatgttca atggtatctc ctctaaaaga ctgaaagttt tctaattctt
    14221 tcaagtcact ttgtcggaga tagaattttt tcttatccgt taatccacgt ccgaaaaata
    14281 aatataatac aaagcccacc ccaggaaggg caaacaatac taagagccat gcccaaatgg
    14341 ctgctacatc tcggggtttg atcaaaatag ccaccaaagc aataagtgca tttaatagat
    14401 aaagggcggt tataatacta gataccacaa aaatgttcct ccttacatac aataacatta
    14461 gtatagcatg atagaagaaa gaagcctacc aaggtgaata tacttttcac tcctttcatg
    14521 aaaatgtagg taaatcgggc taaagtagtt gctttttgta ggttaataag gtaggatatt
    14581 agtacagttg aatatctcct taggggagta accggcaacg tttgttgcga taatatcaac
    14641 agtaagttaa ccaaatggtt ttctggtatt gtatgaaatg gtgagaccta agacaaatgc
    14701 gtatttgtct taggtctctt ttttttcaga caggactagg gccaagatca aaaaatgggg
    14761 gatgaaattt ggaaaacaag gaacaagcac aacaagcggt ctataaagaa acgatcgact
    14821 cgttgatgca gcaaacgcag agctcaaccg atggattgag caccacgcaa gcgaaggaaa
    14881 aattagaaag agatggcttg aaccagctaa aagaaaagcc gaagaagcca acttggaaat
    14941 tgttcttaga aactttcaaa gatgcaatgg ttatcgtatt gctgattgtc gcactgattc
    15001 agatggtcat gggtgactac atcgaattct tagttatttt tgcagtattg atgttgaatt
    15061 ctataatcag tgttgtccaa acaaaaaaag cagaaggttc tttagaagcg ttgaaaaacc
    15121 tttcagcgcc cgatgctcga gtgattcgtg atggtaagga aaaaacgatt ccggcaaacg
    15181 aacttgtggt aggagatatc gtgttgttag acgcaggcga ttatgtacct gctgatggac
    15241 gtttactaga tgcgggatca ttaaaagtag atgaaggtat gctgacagga gagtcgactt
    15301 ctgcagaaaa agaagtaacg gatatcacaa gtacggtacc aatcggagat cgtacaaata
    15361 tggtattcag tggaacgatc gtaacttacg gacgcggtaa attcttagtg acttcaactg
    15421 ggaataatac ggagatcgga caagttgctg gccttttgga atcaacaact gagcaagtca
    15481 ctccgttaca acgaggtctg gataaattca gtaaaaaact aagtttggct attttggcat
    15541 tgtctttatt gattttaggt atccaactgt ttcgtattta tcttggagaa ggtacaggag
    15601 atatgactgc agatatcgtc agcgcagtga tgtttgccgt agccgtagcc gtagctgcta
    15661 ttccagaagc attacagtct atcgtaacaa tcgtgttatc tttgggaacg aataaaatgg
    15721 caaaacgtca tgccattatt cggaagcttc cagcagttga aacacttggt tcgacaagta
    15781 tcatctgtac agataagact ggtacattga cacaaaacaa aatgacagtt gttgactact
    15841 ttttaggtaa tggcgatact ggggatttca caaatgaccc ttcaaaatgg acagctgacg
    15901 aacgtcgctt gatcgaaatc agtgttttag cgaatgatgc atcgatcagt gaagacggta
    15961 ctaaattggg cgaccctacg gaagtagcgt ttatcgactt tagtgaaaaa ttaaaccagc
    16021 cttatcagga aatccgaaac aactacccaa gacaagcaga acttcctttt gactcagatc
    16081 gaaaattaat gtctactgga cacacaattg ataacaaaaa ttacttgttt gttaaaggcg
    16141 gaccagatat cgtcttccaa cgcagtaaaa aagtattgct aaatggtgaa gtcgttccga
    16201 tgacggatga attgatgaaa aaattccaag agcaaaatga agctttttca acacgcgcat
    16261 tacgtgtact agcttttgct taccgtccac ttgataattt tgatttatca tttgaagatg
    16321 aagacgattt gatccttgtt ggtttgcttg ctatgatcga tcctccacgt gctgaagtga
    16381 ctcaggcggt aacagaagca agaagtgcag gaatcaaaac aatcatgatt actggtgacc
    16441 acaaaacaac agctgttgct atcgcaaaac aaatcgggat ttttgaagaa ggaaacctgg
    16501 ctttgaccgg gacggaacta gatgaattga cagaagatca actaaacgaa gttttagaaa
    16561 aagtcactgt ttatgcacgt gtttcacctg agaataaaat tcgtatcgtt cgtgcttggc
    16621 aaaataaagg tcatatctca gctatgacag gtgatggtgt aaatgacgca ccagcattga
    16681 aacaagcaga catcggaatt gctatgggaa cgggtacaga tgtggcaaaa gatgcagcag
    16741 cgatggtatt gacggatgat aactttgctt ctattgtcag cgcagtagaa gtaggacgta
    16801 atgtgtttga taatatcaag aaagctattt cttatctatt tgcaggaaat ttaggtgcga
    16861 tcattgcgat catctttgcc ttagttgctg actggtccaa tccatttaca gcattacaac
    16921 tgttgttcat caatttagtc aatgattcac tgccagcaat tgcattaggt acagaaaaag
    16981 ctgaacctgc tacgatgaac cgcccgccaa gagatccaaa ttcaggaatc tttacggaca
    17041 aaacattgat ttctgtaacg tatcgtggtg tgctgattgg gattgctgtt atctttgctc
    17101 aatggcttgg catgcagcat tcacctgaat tcggtgtagc catgtcattt tcaacattga
    17161 tttggtgtcg gacattgcaa acattcccag cacgttcaaa cacacaaaca gctatccaag
    17221 cagggttctt ctctaacaga agtgtcttac tagctgtagt tgtatgtagc gcgctttact
    17281 gcttaacaat gatcccagga ctgaaagaag tcttctctat cccatcagca tttggattga
    17341 cagaagtctt tacatgtatg ggaatcgcac ttgtgacaat tgttttgatg gaaatcacta
    17401 aattgatcat tgtacgagta caaggaaata aataaaacga atcaacgagg ttgtgagcct
    17461 gccgtttaat tctgagtcac aaggtgcaat ttcaacaaac agcttctcat gtttgttgaa
    17521 tattgtgact tgtgaccgaa gagttggcag gagaacaccg tttaaggaag aagttgtaaa
    17581 atcagcattt tgagctaata ctgagggtca tctgattgga cactgtttat tcggaaagag
    17641 ggactttgac acgactttgg tcacagtccc tttttttatt tatgatagac ggaaagccaa
    17701 tcattttatt attcatcaaa agagatagaa tagataaaag aggagaatga tttattccga
    17761 aaagtgaaaa catataacaa aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg
    17821 aatttgctga agaatattat gaaatccagc aagaatcgca agtaactatt gctgaagatg
    17881 taaaaaatta tctgaaaacg gagaaagtcc tgcctgctga aacagcagca gacgttgctg
    17941 gaggatctgg cagatttctt tccttagcaa aagaaattaa tcgctatgat ttgatcgatt
    18001 tttcttcagg aatgctagaa aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg
    18061 tttcctttat caaacagtcg ttagaagaat ttatccaatc aaatgagaca tatgaaatgg
    18121 tttttacagc agcaaatcca gcattggtac atcttattca attagaaaaa ttgatgaaaa
    18181 agtcaagcaa atggtgcgtg ataatcagag tagtggaatc aatcgatgat gttttttatc
    18241 ctatcgaaaa gcaactagga atgatagaag aagatcctaa tacatcgcca gttgtaatgg
    18301 atcaatttga aacatactta attgatgaag gattcaaagt gaagaaaaaa gattttactt
    18361 attttacaca ggaatcaatt actgaagaat tgatgaagct atactatgac gcgtacgcaa
    18421 aagatcctgt tgtgaccagg tacattcgca aactattcag tgaaaaacga gaaatcctta
    18481 gtacgactaa gctgacctat agactgctcc tttggtccgc agataaaaaa agaacctttc
    18541 acgactcgtg aagggttctt tttatgattt tattatattt tgtagtaacg aatatcattt
    18601 tcgatctttg taatcgaaaa aggtacatct gaagtatatt ctgcacattc tccgtgttca
    18661 ggaagcgtct cactgaaaat cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct
    18721 agcatctctt gatgagattg tgcgaagaga tattcttgat agttttcttc cagataacct
    18781 gtaaaaaatt cacttactgc accagaaccg tagctgaata gaccgatgcg atctcctggc
    18841 tgtagtgatt tcgaattttc cagtagagaa gttagcccca ggtataatga accagtgtaa
    18901 agattaccga ttcgtcggct gtaacggatg ctttcttcat agcgagccat aagacgttcc
    18961 tgattttctt cgtctgtttg gtctaatacg ctttgcaatg ccttttttcc catcttagta
    19021 tacggaatat ggaaagcaat cgcctgataa tcttcgagtc ctcgacccga caattcttta
    19081 tgtcgattcc aaactttttg gaatgattcg atatacgtag aattagataa aggaccatca
    19141 acaacaggaa attcgctata atctggacgc cagaaatcat agatatcttc tgtcagaaat
    19201 acgctgtcgt cttcaatcga taaaatacgc gggttttgag tgatcatcat cgcaacagca
    19261 ccgacacctt gcgtcacttc accaccgctt gccaagccgt aacgagcaat atcacttgct
    19321 atgactagta cttttcgttc tggatgattt ttgacatatt ctttcgccat gtgcaaagct
    19381 gcggtgccac cgtagcaagc ctcttttact tcaaaagaac gagcaaaaga ttggattttc
    19441 agtaaatggt ggataattac cgcactcgct tttgaatgat caatcccgga ttctgttccg
    19501 acgatgacca tgtcgattag ctcacggtct ttttctgtta cgattttgct ggcagcattt
    19561 gctcctagtg taatgatgtc ttcatttgca cgattgactg ccatttggtc ttgaccaatc
    19621 cctatatggt attttgcagg atcatcccca cggctttctg ccaactctgt catatctaaa
    19681 tataaattag gaataaaaaa ggaaagacga tcaatcccta ttttcatttc aacacctctt
    19741 tacttatgat aaaaaactta ctttactaag gtatcataaa aagattaaaa gaaatataaa
    19801 aaagagaata tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag
    19861 ctatttgttt ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa
    19921 gtcgttatga tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca
    19981 tttactgcag ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg
    20041 aaaaaagata aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa
    20101 aatgttgcca gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg
    20161 atcaatgaag tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa
    20221 ttaggtgaag cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg
    20281 ctgaaacagt atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac
    20341 gacggattga ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca
    20401 acacaatttt ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa
    20461 gcagcacatg ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct
    20521 gatgaagacg tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg
    20581 ggcacgttac gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg
    20641 ttgaatgacg gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat
    20701 ctgccttatt tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg
    20761 ggaatcgctc caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca
    20821 acaatcgatc tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa
    20881 gaactgcagt tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat
    20941 ccaattggtg caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa
    21001 cagaagagat acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg
    21061 ttagaagcga atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt
    21121 acgccatctg aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg
    21181 ttgatttttc aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa
    21241 gtgagtgaag tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa
    21301 aaatggattc cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca
    21361 aaaatctgtg gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt
    21421 ctatcaggaa aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag
    21481 ctgattcttt gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa
    21541 gatatctcta ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta
    21601 gtggatgtaa aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca
    21661 aacaagttac gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt
    21721 gctacagaat cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac
    21781 aaagaaatcg gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt
    21841 gacccttacc gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg
    21901 gcagctacag gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga
    21961 aatggattat accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa
    22021 ctaacggtgc ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca
    22081 aaagcatctt tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct
    22141 gcagtagggt tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa
    22201 aaaggccaca tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag
    22261 gaaatcgagc aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct
    22321 atacaaatat tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag
    22381 caagatttac agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg
    22441 tttattatta gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa
    22501 gatatcttca ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga
    22561 caggtcaagc tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa
    22621 attattatat gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat
    22681 ttttatcgat cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat
    22741 ttgactttgt atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata
    22801 gaaatagttg ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt
    22861 tcattttgtt ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa
    22921 cttaaagcgg cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt
    22981 tccgtttttt cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc
    23041 gcagttggtt catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga
    23101 agattgtcac ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca
    23161 gtattgaagt tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct
    23221 aatccgatcg ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca
    23281 taacgtcgca agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat
    23341 gaaggacgga attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt
    23401 cgctcatacc ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa
    23461 aacttgcgta tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga
    23521 aaaataaaaa atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt
    23581 ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag
    23641 ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt
    23701 gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg
    23761 gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata
    23821 aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc
    23881 atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt
    23941 attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag
    24001 cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat
    24061 ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc
    24121 atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg
    24181 attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa
    24241 attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca
    24301 tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat
    24361 caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat
    24421 cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct
    24481 aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc
    24541 agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc
    24601 cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag
    24661 acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata
    24721 agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt
    24781 taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa
    24841 gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa
    24901 actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat
    24961 tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca
    25021 gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt
    25081 gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca
    25141 gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc
    25201 aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc
    25261 ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct
    25321 gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa
    25381 aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa
    25441 aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa
    25501 tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg
    25561 ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct
    25621 tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta
    25681 caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa
    25741 ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg
    25801 gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa
    25861 tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa
    25921 ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt
    25981 gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc ttatttcttg
    26041 gagttaaacg cttctgtccc agcctctttt tatctaataa aattttaaga ccatttacta
    26101 attatcgatt ttttctgccg catttttagg cacttcagaa gcctttattt cttcccagct
    26161 taatacacct ttacgaggat tgactttgag tttaagatac gcattcatct ttaatggatg
    26221 ttctctttct tcgcgaagcg tcacctgttt tttttcacca tctttattat aagccgcttg
    26281 cttgtaggta taagtcgtga atttctctcc gttatctgct tgggtagctg acatttcgcc
    26341 attcgtcgtg atttttgtat aataagcttc gccgccgtaa aaataatgat aagctgcaaa
    26401 acttccgccg agaaatatgc ctaaaacgac aagtacgcca attaattttt tcatgtactt
    26461 cacctctttc cttattatta acgaaataga agatttcgtc tattgaaagt tgttggcaac
    26521 agctgaattt taaacttttc ctcattttgt tcttattgct tcaaaagaaa gttaaggact
    26581 atcttgaagt ttttctcaaa aaacacattt ttttatttat aaaaggtact tttttcgcgt
    26641 ataagacaga cgagtgctct tagttgactt tgaccaatat tgacgtataa taagcttagt
    26701 tcgaatctta caaaaagtaa gtcggacgta ttctttttga tttagtcaaa aaaagactat
    26761 aataaaaagg tgagagctga aatttttcag tgatctatat tatttaggag gtttgtaaat
    26821 tatggcaaaa gaacattatg acagaagtaa accacacgtt aacattggta cgattggaca
    26881 cgttgaccat gggaaaacta ctttaactgc tgcgatcact acagtattag gcaaaaaagg
    26941 cctagcaaat cctcaagact atgctagtat tgatgcagct ccagaagaac gtgaacgtgg
    27001 gattacgatc aataccgcac acgtagaata tgaaacagaa aaacgccact acgcgcatat
    27061 tgatgcacca ggacacgcgg actatgtgaa aaacatgatt acaggggcag cacaaatgga
    27121 tggtgcaatc ttagttgttt ctgcaactga cggtccgatg cctcaaacac gtgaacacat
    27181 tttattgtca cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca aagttgattt
    27241 agtcgatgat gaagaattga tcgatttggt agaaatggaa gttcgcgagt tattgagcga
    27301 atatggtttc ccaggcgatg acactcctgt gatcaaaggt tccgcattaa aagcattgca
    27361 aggcgatcca gatgctgaag ctgctattat ggaattgatg gatacagtag atgaatatat
    27421 cccaacacca gaacgtgata cagataaacc attactattg ccagtggaag acgtcttctc
    27481 aattacaggt cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg
    27541 tgatgaggta gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt
    27601 agaaatgttc cgtaaaacgt tagattacgg ggaagctggg gataacgtag gcgtgttgtt
    27661 acgggggatc caacgtgacg atatcgaacg tggacaagta cttgctaaac caggttccat
    27721 tactccacat acaaaattca aagcagaagt gtacgtgttg acaaaagaag aaggtggacg
    27781 tcatactcca ttcttcaaca actatcgtcc acagttctac ttccgcacaa ctgatgttac
    27841 aggaacaatc acattgccag aagatacaga aatggtcatg cctggtgaca acgtgacgat
    27901 tgatgttgac ttgatccatc caatcgctgt tgaaaacgga acgacattct caattcgtga
    27961 aggcggacgg acagtaggtt caggtatcgt tacagagatc gaagcataag aaacgcgact
    28021 cgaatatttt ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt
    28081 ttggaccgct ctttgttctt caattgtata agaagagatt gtagaagcat gaactttcgt
    28141 tttacttcag tctcttttat tcatcatgag agtgttcatc tatcggtatg cagtttttaa
    28201 tactttcttc gtatccattt tttcaaacca cttattctac cttgtgtctg ctcaactggc
    28261 gcattatcaa taatcagcaa agcaatcata acatatgcaa tccaactatc tctagaatat
    28321 agagtataac gtgagaccca gtttgtagcg tacttgcttt tatattctct taatccatgg
    28381 aaagaataaa aatgagaacc aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa
    28441 ctctttctgg aagttccgac atttgaaaga ggggccatcc ctaaattgaa ccattggata
    28501 tgttcttctt tcatataggc aaacaaatgc aagaacaaga aatccatact gccagaaggt
    28561 gcttttttag aatcatatcg catcagatca atcgttccta ctttattgtt cgtgtaagta
    28621 ggcatgatcg ttgcaaaagc gacaatttct tcttgggtat ttttgacaac tgcaataggc
    28681 gctctttgta gataatcttc agagaaaaag cctaaagaaa accctttttc ctttcgtgaa
    28741 cccaaccaat tatcagagat atttttgaaa gtactcattt gctcagtaga aaatggtggt
    28801 tgtaagacat caaatgtaaa tccttctcgt tcgatccgat tcaagacagc acgagtgccc
    28861 ttcatttttt tccctgaagt tgtaaaacta ttcaggtcta cataagcttc ttcccccatc
    28921 ttaatgaaat cgtagccgaa ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag
    28981 aaaactggta aatagcatag tcgatctgtt tcttcgataa aagcttcgat tgcttctgga
    29041 aaatcttctt tcttaccaga aggatcaccc attacaatac atttattatt gaagcaagcg
    29101 aattggagaa gaacagttgg ttcaccgtct ttttcatagg caaacatccg cttatctttt
    29161 aagaagatca attgactatc ggagtttcct ccataagttg taaggatctt cagggccttt
    29221 tcttcattaa aggcttcgcc aatctgtttc ttttctcctt gaaggaaatg aacaaataga
    29281 acgatcatga aactaacagc gatgatggcc aacaatcccg aaaaccaaat cttttcagaa
    29341 ggaaataaga aaaaggaaat aaaatggtga cgccgatgag ggaaatctgg cagattgtat
    29401 accccaataa cgatgtaaag caaggacagt gcaccaataa tgattccatc gatcgtacgc
    29461 cactcccatg aatagatcaa ttgttcccga aataattcgt ttttagaagc aagaatgatc
    29521 agaagcagaa tagacaagaa aaccaccggt gtgaaactaa aatcacttaa taaaacataa
    29581 agtaaagcta gaacaatcaa gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg
    29641 atccctctgc ccataatgat taaaagaaat cccaatagta tactaggaaa ttggataata
    29701 aaatgaaatt tcaatgggtt caaactatga agccagcgaa actctgtaaa agcttgcggg
    29761 atagtggcag aaagtactag catgattcca gaaaagtata ataagacaac cacgatttta
    29821 tgcgcaattt ctgttgctaa ttgtttaggg ataccagaat aacgctgatc aaaagtggaa
    29881 ccgatatttt tgaagaaaaa gacgattcca atcaaaaacg gaatgatgta gtagaacagg
    29941 cgatagagca agatccacac aacgactatt tctcttggca caccaatagc ggacaacccg
    30001 ataatcatca ttacatcgaa actcccaatt tctcctggaa tcatagacac gattcctatc
    30061 actgaagcag caatgaataa tggaattgtt tgccacagat caatccggat ttccattaaa
    30121 taaccaacag aaaggaaact aaacaggaca ccggtccatt ccaacaatga aactagcaat
    30181 agctgtcctt gagttttaag tgaggtacca ccaaggaatc ctttcttttt gaaagtagta
    30241 aataaaaaga cgacaggaaa atatagaccg ccgccgatca accatatcca atattgcttc
    30301 aaaaaaggag caactggcgt gaagactaca agtaaaaaag aaagcagact gtaaatagaa
    30361 agtccagcca tcaaaaacaa gaaaactttc gataatgctt ggatcacgtt tctgctctct
    30421 ttcttttgtc catatagttc agagcgaagc cccacactaa caaacccgcc gaaaccggca
    30481 atattgttga tcgtattgat cagccagctt gtctcaaaca ggtaacgagg attctgcttt
    30541 tgttcaagca tccgattcaa aataatatca taaccaacca taggtaacac agagataaga
    30601 ccaatcaata gcattagtcc gcttttccat acaggtatag tggcaaacgt ttctcctaat
    30661 tgctggatag atagagtttt accgatggac atcaattcac cgacaataat gacaatgaca
    30721 gaaatcaaaa agattgtttt gaacagtcct aggtggtttt tcagccattg tatggtattt
    30781 tttaacaaat aaatcacctt ctattcctaa tagttatgtt tcagaaagaa attgaagaac
    30841 ttctcgattg aagcgttcag gatcttttct agctaattca tgtccttgtt ctttcacaag
    30901 cacaaaggaa gcttttggta tagttttagc tatatacaaa gaatgtttta gcttgattac
    30961 atcttttttt cccacgatga tcaaagtggg ggagttgatt ttttttaaat cattttctgt
    31021 aagcccgatg tcatgcagca aaagtttgat aactaaaaga tttttgcgaa gacttgggcg
    31081 aaataaagag agtaaccata cccatgcata atgaatatta ctgatgactc tggcagaaaa
    31141 acgaacgcct ttaacaagcg tgtttccaga atttaaaatc aatcgatgaa cttttttagg
    31201 gaagctgctg gcaaatacca gtgctagatt tgctccatca ctaaatccaa gaaaatctgc
    31261 ctgatcgatt ttttccagca acatgatcgt attcagatcc tcggccatta actgaaaatt
    31321 caacatagat gcttcgtttg tcgaacgacc atgtcctcgg ctatctacta gatacacggt
    31381 atagtagcgt tcgagtacag ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc
    31441 atgcagtaaa aagagaggga agccttgacc gctcttttca tagtaaattt cgctcccatc
    31501 tggcattttt gcatatttct tttctttttt cacataatca cctactgtgt aaagtataac
    31561 gattatatca gtcattgggc aattgttttt actgaaaaac aacgatcatt ttcgtaagat
    31621 gtcaaaaaat acaggaaaat tcattttttc ttaaggcgta cacagaaatc aaggaagaaa
    31681 tagccaagaa gataaagaaa tagtaagata aaaaaagatg tcaaaataac taggtgatga
    31741 aatgaagcga aaacgattat ctattatccg tattcttttt tacatgatca ttctgacggt
    31801 tattggtgcg gtgttgtttt taggaggaag aacttatcgt tcggtaaaac gagtggaaag
    31861 ctatcaaata gaaataacaa cagctgcaaa aaattatcat atggaaaact acgagaattt
    31921 gatcaaggcg ataatattga ccgaatcaaa aggaaaaggg acagatctca tgcagagctc
    31981 ggaaagtctg catggagaag ctgagatcat tgataatcca gctgacagta ttgatcaagg
    32041 tgtcaaatat ttggcggaaa tgatagtaga agcaaagaaa caaggatgcg atttatggac
    32101 agctgtccaa gcatataatt ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg
    32161 agaaaacaca gtagaattag cagaagcgta ttctaaagat gtgctgagcc cacttttagg
    32221 aaatgaggaa gggaaacaat accgatattg gcggatccag tccttgcttt acaatggcgg
    32281 ctatctctat cataatggag gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa
    32341 aataatagag acctatgaaa aagtctttaa gtaaaatagc aggaaatgtt caatcatgaa
    32401 taaaattaaa tgaaagaagg agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc
    32461 aagaagtggg gtacacaacc aaagactgga tgttacggtt tgtgaaggga atgtttatcg
    32521 gttcaggatt tatcttgcca ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt
    32581 atgagcggct gatttctttt ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt
    32641 tttttctgcc tgttggtcta ggcggagtga caggcatctt tctactttct tttttagtca
    32701 gttttttatt aggtgcgtat gaaacaacga tattatggtt ttttgtcgga tgtatcgctg
    32761 gaactgttcc tgcgttatgg aaagaagcag ggaaaaaagg aagagatact tctgatgtga
    32821 tcatcatggt tgttactttt gttctggctt atttgttttt attatacggc gctcaattat
    32881 ttgacgggca agtcgatcag aattttggaa catggctgat tgccggcgga ttgattggtt
    32941 tgggtatgat cgtcccagga ttgagccctt ctaatttttt ggtgtatatg ggattgtata
    33001 aagcgatggc tgacggattt aaagaagtac gacttgaagt gattgtgccg atcggaattg
    33061 gtgggattct ttgtgttctt ggattgtcaa aaatcatgga ttacattttc tcaaaggcat
    33121 atagcaagct attccatttc attttaggtg tagtttttgc ttcaacgatt atgatcattc
    33181 ctaccgatta cgcgggattg ggagttgctg gggtactagc ttgtcctgtt ctttttatag
    33241 ccggtacagc actaggttgg tggatgagcc gtttggagga acaatataag taaagataga
    33301 ttgataataa aaacagcaca cgggtgattc aaacaaaaag gttggcatct tttttgtaaa
    33361 atcattcgtg tgtttttcta taaattttat aaaaacaagt tgtttttaat cttggaacac
    33421 gctagactta aacacgtgat tatttttgaa agttggcgga aaatggagaa aaagaaaatg
    33481 aatggactta cacagcaaga ggtagttcag aaaatggctt ctggccagca aaatgactac
    33541 caggaagatg catcaaaaag tacaaaacaa atattcagcg ataatatatt gacgttattc
    33601 aattttctga actttggtat tgggatttgt ctgttatttg taggtgcgta ttccaacatg
    33661 gcgtatttag caattattgt cgtcaatatc gttattggaa tttatcaaga aatacatgca
    33721 agaaatcttg tacggaaatt atcgattgtt tcccaatcag aagtactagt gatccgggac
    33781 ggtaaagaac aatcgatttc tactaaagag ctggtattag gagatttggt aaaaatcgga
    33841 gcaggagaac agataccagc cgatttacag gttatatctg gacgggcaga agcaaatgaa
    33901 gctcttttga caggcgaatc tgatttgatt gtcaaagaaa ctggagctga attgctttct
    33961 ggaagctttt tgacaagcgg ttctgtcatg gctgaagtta tccgagtagg tgcagataat
    34021 tatgctgtcc gcttgactag cgaggcaaag actcacaaag ctattcgttc tgaacttgta
    34081 gattcgattc gcaaagtatc caaattcact agtttcgtga ttattccttt ggggatcata
    34141 ctatttttgg aagcactgtt catccgcgat gcttctatca aaatttctgt tattgcatct
    34201 gcagcagctt tgttaggcat gcttccaaag ggtttggtat tgctaataag tattgcatta
    34261 acgacagggg taaccaaact ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt
    34321 gaaacgctgg cccatgtcga tacattatgc ttggataaaa cagggaccat tactgaaggg
    34381 aaaatgagta tccagcgggt agaagcacta catccgctgt acgagaaagc catcccagaa
    34441 attatgggga cgtatctggc agaaagcagt gataacaaca tcactatgcg ggctatgaga
    34501 gattattttg agctttctaa tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat
    34561 cgcaaatggg gcgcgatgga atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa
    34621 cgtttggtgg aagaagatcg gcttccggac agtctaaaaa cagcccaagc gaatggctat
    34681 cgcgtactta tgttggggat cgctccaaat cagcaattga acgaagaaaa accagcattt
    34741 gttgagccgg ttgctctgtt tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca
    34801 ctagcttatc ttcatgagga aggtgtggat ctgaaagtga tttctggaga caatcctttt
    34861 actgtctcca atatcgctag acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt
    34921 tctcaaatta ctgaagaaat ggaagtgcga gaagctgctc atcgctatac ggtttttgga
    34981 cgagtgagtc cgcagcaaaa gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg
    35041 gttgcaatga caggcgacgg tgtgaatgat gttttggcgt taagagaagc agattgcagc
    35101 attgctatgg cagaaggtga tggagcaaca cgtcagattg cgaatctggt attgttggac
    35161 tctgatttta ctacattgcc agaagtcctg tttgaaggac gccgagtggt caacaatgtg
    35221 acgaaagtct caggcatctt ttttatcaaa acgatttatt catttatttt atcgattata
    35281 tgtgccgtta cagcaattgg atttccgttt atccctatcc aaatcacgct gattgattta
    35341 gcgattgaag ggtatccttc cttcttttta tcttttgaac aagataaaag aaaaatcact
    35401 taccgttatt tgcctacagc acttattaat gctttaccaa atgccttgct tgtagtagtg
    35461 aatatcattg cggtgtatct acttggaaaa acattcgcat ggggaaatgc tgaaactact
    35521 actttgatgt attacttgct gattgggatc agttgcatgg cagttgtaaa agcttgttat
    35581 cccttcaacc cattgcgcat cttcctagca gtaacgacga tcgtagggat atatgtagct
    35641 gcaatgctgt tccatggaat tttggaagta aacttagggt tgggagagag cgtaggatac
    35701 ttctttgtat tcatgctcgt aaatattgtt cttcgagtat tgtactggaa ggctgatatt
    35761 caaaatcagt tactgaaaag agtagcaaat tgatgcttaa tgagatagaa atgtgttata
    35821 cttgaaaaag caatgaaata tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg
    35881 cactgatttc agttagtgcg attttttacc ggttattctc ctgaaatatc ttctgttaaa
    35941 cccaaaagat atcaatagag cagggggtga aaaaatggct caacggattc ctcaagaggt
    36001 tatcgaaaca gtacgcagtc aaacgaatat cgttgaggtg attggacaat atgtccagtt
    36061 gaaaaagtct ggtaaaaatt acttggggct gtgtcctttt catgaagaac gtacaccgtc
    36121 tttttctgtt gcagaagaca agcagatttt tcattgcttt ggttgtggta aaggcggaaa
    36181 cgtgtttact tttcttcaag aactagaagg tctaagtttt ccagaagcag tggtaaaagt
    36241 ggcagacttc gaacagatac cgttagaaga tcaatggcgt cagcgtacta tagctgtcca
    36301 aaatcctgaa tctgctacgg ggaaactgat tgctgctcat gaaaaagcag cggaaatcta
    36361 tcatcacatg ctattgcata caaaagctgg acagccagct ttagaatatt tgcaaagtcg
    36421 tgggttgtct ttagaattaa ttgaagaatt caacataggt tttgcaccta atgagcgttc
    36481 ttttcttcag caagtattca agaatgaatc aatttcaaat gaattgttag aacgctctgg
    36541 attgtttgtc acgcatgatg atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt
    36601 tccacttcgt aattctcaag gccagacgat cggtttttca ggacgctggc ttgcacctga
    36661 aaaagggcag gaaaaagatc agcccaaata cttgaatagt ccagaaacag aactgttcaa
    36721 taaaagacaa gttttattta atcttgataa agcaagaagc gatatccgga aaaacggaga
    36781 aattttgttg ttcgaagggt ttatggatgt gattgctgca tggcaggctg gtatcaaaac
    36841 tggattagct tctatgggga caagtctaac agctcaacag atccaacaaa tggaaaagct
    36901 gacgaaagaa ttggtctttt gctatgacgg agacaacgca ggttttgaag caaccaatcg
    36961 agggattgaa ttgcttcggc aaaacagtcg attagcactt tctgtcgtag tcgttccaga
    37021 aaagcttgat cctgatgaat atctccgtaa gtatggagaa gcatctttcc aagaattagt
    37081 ggctcatggg cgcgaaacag tctttacttt taaatcacgt tatttaaaac aagggaaaaa
    37141 tttagataat gaaaaagaca agatcgaata cctcgaagaa ttactagttg aacttagccg
    37201 agttgtttca ccaatcgaac aagatatgta tctatctcaa ctgtcaacag agtttcagat
    37261 cggcagagag acgatacaaa aacaactgcg cgatcttcga aggacaaatc agcaaaatcg
    37321 tcaagaacct caggaaagtc aacacactca ggttacgaga caagaaactg cacggaaaaa
    37381 gagacctttg acgcaagtag aaaaggcaga gcagattcta ttatatcgtg catttaaaga
    37441 agtttctgtc cgtaatattt taaaagaacg agaatttcag tttattcatg atgcatatgc
    37501 agaagtttat tttttattcg atgcatatgt ctcacaacat tatgaattca accttgcaga
    37561 gtttttagac tttttgcaag atgaaaattt aaggcggttg gtggtggaaa tcgaatattt
    37621 accggtggca gaagaaagtt cgccacgaga aatccaagac ttgctagatg tgatcagcaa
    37681 atctggctta gctgatgaaa taacattaaa aaaacaaatg cagcaagaag ccagacgaac
    37741 tggaaacaaa cagcttgagc ttgaattgac gattgaaatc atcaatttaa cgaaacagtt
    37801 aaaacaagcc aaatagctac tcaagggggg ccttctttta tggcaaatgg aacagataaa
    37861 aaaacgtatg aagcagcagt agcagctttc atcaaagaaa acaaacccaa acgacaagtt
    37921 gtatatgatg atttatccaa tcagcttgct acaccattca ctttgaatgc agatgaaatg
    37981 gacaaattga tccaaaagat tgaagacgca ggtatcagtg tggtggatga aaatggtgat
    38041 ccatcaattc acagcttgaa gagtgctgag aaaaaagctg aacaagcaaa aacagaagat
    38101 ctttctgcgc caaccggtgt aaaaatcaat gacccggttc gtatgtatct gaaagaaatt
    38161 ggccgtgtct cccttttaac tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa
    38221 ggcgaccaag aagcgaaaca gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc
    38281 gctaaacgtt atgtaggacg aggcatgcag ttccttgact tgatccaaga aggaaacatg
    38341 ggactgatga aggcagttga aaaatttgac taccgcaaag gatttaagtt ttcaacctat
    38401 gctacatggt ggattcgtca agccatcact cgagcaatcg ctgaccaagc acgtacgatc
    38461 cgtattccag ttcatatggt tgaaacaatt aataaattga tacgtatcca acgtcaattg
    38521 ctgcaagacc ttggaagaga acctacgcca gaagaaatcg gtgcggaaat ggatcttcca
    38581 acagaaaaag tccgagaaat cttgaaaatc gcgcaagaac ctgtttccct tgaaacgcca
    38641 atcggtgaag aagatgactc tcacttaggt gatttcatag aagaccagga agcaacaagt
    38701 ccagcagaac acgcagctta tgagttacta aaagaacaat tggaagatgt actagataca
    38761 ttgactgatc gggaagagaa tgtccttcgc ttacgttttg gtttagatga tggccggacg
    38821 agaacattgg aagaagtagg gaaagtattt ggtgttactc gggaacgtat tcgtcagatc
    38881 gaggctaaag cattaagaaa attgcgccat ccttctcgtt caaaacaatt aaaagatttc
    38941 ttagaataag cgtggactat tgaccagaag agaaatcagt aaaactgttt ggtttatttt
    39001 aaaagaaaaa aa
//
LOCUS       DAPBBR010000025        36834 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPBBR010000025 DAPBBR010000000
VERSION     DAPBBR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.025"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="RD488_001384"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="RD488_001384"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7657468.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            1710..2027
                     /locus_tag="RD488_001385"
     CDS             1710..2027
                     /locus_tag="RD488_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7657469.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(2231..2596)
                     /locus_tag="RD488_001386"
     CDS             complement(2231..2596)
                     /locus_tag="RD488_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657470.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            2804..3286
                     /locus_tag="RD488_001387"
     CDS             2804..3286
                     /locus_tag="RD488_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657471.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            3483..4373
                     /locus_tag="RD488_001388"
     CDS             3483..4373
                     /locus_tag="RD488_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HDT7657472.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            4698..7169
                     /locus_tag="RD488_001389"
     CDS             4698..7169
                     /locus_tag="RD488_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7657473.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7272..9008)
                     /locus_tag="RD488_001390"
     CDS             complement(7272..9008)
                     /locus_tag="RD488_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDT7657474.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9005..9709)
                     /locus_tag="RD488_001391"
     CDS             complement(9005..9709)
                     /locus_tag="RD488_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7657475.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            9840..10343
                     /locus_tag="RD488_001392"
     CDS             9840..10343
                     /locus_tag="RD488_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDT7657476.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10303..10641
                     /locus_tag="RD488_001393"
     CDS             10303..10641
                     /locus_tag="RD488_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDT7657477.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10662..12080
                     /gene="ffh"
                     /locus_tag="RD488_001394"
     CDS             10662..12080
                     /gene="ffh"
                     /locus_tag="RD488_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDT7657478.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12192..12770
                     /locus_tag="RD488_001395"
     CDS             12192..12770
                     /locus_tag="RD488_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDT7657479.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            12774..13295
                     /locus_tag="RD488_001396"
     CDS             12774..13295
                     /locus_tag="RD488_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7657480.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13374..13928)
                     /locus_tag="RD488_001397"
     CDS             complement(13374..13928)
                     /locus_tag="RD488_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7657481.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14181..14456
                     /gene="rpsP"
                     /locus_tag="RD488_001398"
     CDS             14181..14456
                     /gene="rpsP"
                     /locus_tag="RD488_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDT7657482.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14468..14719
                     /locus_tag="RD488_001399"
     CDS             14468..14719
                     /locus_tag="RD488_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDT7657483.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            14844..15635
                     /locus_tag="RD488_001400"
     CDS             14844..15635
                     /locus_tag="RD488_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657484.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            15805..16326
                     /gene="rimM"
                     /locus_tag="RD488_001401"
     CDS             15805..16326
                     /gene="rimM"
                     /locus_tag="RD488_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDT7657485.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16316..17077
                     /gene="trmD"
                     /locus_tag="RD488_001402"
     CDS             16316..17077
                     /gene="trmD"
                     /locus_tag="RD488_001402"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDT7657486.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17213..17560
                     /gene="rplS"
                     /locus_tag="RD488_001403"
     CDS             17213..17560
                     /gene="rplS"
                     /locus_tag="RD488_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDT7657487.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            17818..18111
                     /locus_tag="RD488_001404"
     CDS             17818..18111
                     /locus_tag="RD488_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDT7657488.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            18954..21281
                     /locus_tag="RD488_001405"
     CDS             18954..21281
                     /locus_tag="RD488_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7657489.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            21407..21736
                     /locus_tag="RD488_001406"
     CDS             21407..21736
                     /locus_tag="RD488_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HDT7657490.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            21776..22780
                     /locus_tag="RD488_001407"
     CDS             21776..22780
                     /locus_tag="RD488_001407"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7657491.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            22777..24206
                     /locus_tag="RD488_001408"
                     /pseudo
     CDS             22777..24206
                     /locus_tag="RD488_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            24412..25584
                     /locus_tag="RD488_001409"
     CDS             24412..25584
                     /locus_tag="RD488_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7657492.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(25746..26201)
                     /locus_tag="RD488_001410"
     CDS             complement(25746..26201)
                     /locus_tag="RD488_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657493.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            26791..27213
                     /locus_tag="RD488_001411"
     CDS             26791..27213
                     /locus_tag="RD488_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657494.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(27379..28572)
                     /locus_tag="RD488_001412"
     CDS             complement(27379..28572)
                     /locus_tag="RD488_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7657495.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            28796..29173
                     /locus_tag="RD488_001413"
     CDS             28796..29173
                     /locus_tag="RD488_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7657496.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            29161..29499
                     /locus_tag="RD488_001414"
     CDS             29161..29499
                     /locus_tag="RD488_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7657497.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            29633..30076
                     /locus_tag="RD488_001415"
     CDS             29633..30076
                     /locus_tag="RD488_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HDT7657498.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            30338..31153
                     /locus_tag="RD488_001416"
     CDS             30338..31153
                     /locus_tag="RD488_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7657499.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            31163..31825
                     /locus_tag="RD488_001417"
     CDS             31163..31825
                     /locus_tag="RD488_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7657500.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            32030..33694
                     /gene="alsS"
                     /locus_tag="RD488_001418"
     CDS             32030..33694
                     /gene="alsS"
                     /locus_tag="RD488_001418"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDT7657501.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            33707..34417
                     /gene="budA"
                     /locus_tag="RD488_001419"
     CDS             33707..34417
                     /gene="budA"
                     /locus_tag="RD488_001419"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDT7657502.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            34547..35044
                     /locus_tag="RD488_001420"
     CDS             34547..35044
                     /locus_tag="RD488_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDT7657503.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            35229..35489
                     /locus_tag="RD488_001421"
     CDS             35229..35489
                     /locus_tag="RD488_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657504.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(35851..36090)
                     /locus_tag="RD488_001422"
     CDS             complement(35851..36090)
                     /locus_tag="RD488_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657505.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            36376..36690
                     /locus_tag="RD488_001423"
     CDS             36376..36690
                     /locus_tag="RD488_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657506.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT        12484 a         6331 c         7273 g        10746 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatatta tagattacaa atagtatcgt
     1441 atttcgcaat cttaaaatta tcttcttact atgaataaga taataaaatt tgtatttgtc
     1501 ctttttaggt aacttatttt aatctatata cctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatggt aactatgcac tgtaacgata atgctgctaa aatatctttt
     1621 tacgaaaaac atcacaagga aaaacttaac tatggtatta tctaaacata attttttcgg
     1681 tatttaatat ttaattagga gggaatattt tgctttttta tagtaatttt atcttaatag
     1741 tagcgatatt attacttctg aatatatgga tttttgatag gagtagaaat gcaagtatag
     1801 gttttagaac taaacgaagt ctgtcttcta aaaaaaattg ggtatactca caaactattt
     1861 tttatggagg aattgtttta attagtttac tttcttcaac actttattct ttgaatatta
     1921 tagatgtttc cacctcaaat tcaatatcta ttattggaat cattattgct gcaattatta
     1981 cacaactgtt tttagtgttt ggagagaaga aaagaagtaa aaaatagaaa aactagtgat
     2041 agttttggtg atagtgatat taaaaatcag aaaagataga aaaagcagga gatagataaa
     2101 atgctgatat ttcagcattt tttaagagta taaaagagaa aaaaagtaat aaatgtatac
     2161 atgatataag aaaaacatat atgtataaaa agaagaaagt agcttctctt tgtacatata
     2221 tggtttgttt ttatggatgc cgagcttttt tataagataa ggctaccgcc cataacgacc
     2281 caaggatttg tggaactaag taaatacctg caagaagcaa gatcagctgg gtcggtttta
     2341 aaggatgata gaagtaacgc cattcagtaa aattggcgca aaataaatag gaagtgacag
     2401 tagatataat attggcaatg aataaagata taatacgcct gttcctttga aaataatatc
     2461 cagcaaaaag agataaaaat atcaatgtga tgaacccgct tacggaatga taacgaaaat
     2521 caagcagtaa ggcgaaatgc acataaggaa caaaagataa aagcaacgga aggtttttcc
     2581 agcaagtttt tatcatcttt catcaccacc taacaagtgt tattattttg ttagttttat
     2641 tgtaaattga atcctgcaat aatcaattac tttttcatta tttctagatt aaatgaataa
     2701 actctcatgc cattatctct aaaaaaaaag tttttccccc taattttttt agatagaaaa
     2761 ttgtatagta tgatgagaga aaaagtagtt tgggggaacg ttaatgagaa gaaaagcagt
     2821 aatcgatcgg ctttatttat ttttttggtt ttttcctatc gttttgctac cttttacatg
     2881 ggtaaatgct gttgtacaag gtgcggagat attaggcctg atccaaggaa gcggatttgt
     2941 ggtttctagg aattttccag ctttgactgt tttctattta gtgataagtg taggtctctt
     3001 attaccaaaa tctctgatca atcactacaa ttggcagctg ctttactttt cttgcttatt
     3061 agtatttaca tctatgtttt ctttgctgcc tcgcttgatt atcggcccta atggtttgag
     3121 cgagagtgga ttgaaggatt cagcttattc ctccatgtat ttcttgacga tcaaaccatg
     3181 gttctattta gtaattgcct catttattct tgcaacattt ttttacttct ggacagaaat
     3241 caggataaaa agtgaacgat ctgtatctat aaaaaataac tattgatggt ggatcatcag
     3301 taaaaaagca tatgagctgc gtaaaatgca tgtttctcat atgctttttt tattattatg
     3361 taaagaatgc gaaaaacgtt tacatgattt ttacataact taactatatt tttacagcaa
     3421 ccatacgagg gatttacagt cgactgataa actttagttg taaataagaa aggagcaata
     3481 aaatgaaaaa agtattgttt actctaggta tgatgggaat tcttttagcc ggatgcggct
     3541 caggatcagg aaatacagat ggctctgcca cacaaaataa ttcaagtgac tcaaatgaac
     3601 aagtaaaaat cgttgcggta ggttcgacag cattacagcc gttagtcgat gcagcacaag
     3661 aaagctttgt acaagaaaat ccaaattatc aaatctctgt acaaggagga ggaagcggaa
     3721 ctggtttgag ccaagtcgaa gctggagcag ttactatcgg aaactctgat gtatttgcag
     3781 aagaaagaga cggagttgat gcttcaaaat tagtggatca taaagtagca gtggtcggga
     3841 tggcgccaat cgtcaataaa gatacagatg tcaaagatat caccaaacag gaattgattg
     3901 atatctttac aggaaaaatc actaactgga aggaagttgg cgggaaagat caaaaaatca
     3961 acgtcgtgaa ccgtgcaaac ggcagcggta cccgcgcgac attcgaaaaa tggggactgg
     4021 atggtgctac ccctgtgcag tcccaagaac aagattcatc aggaacagtt cggcagctgg
     4081 taagtcaaac accaggagca atcagctatt tagctttctc atatctcgat gattccacac
     4141 aagcactaag tatcgacggt gtagaaccaa aagaagagaa tgtagcagat aacagctggg
     4201 gaatctggtc atatgaacat atgtacacga acggaaaacc ttcccctgaa gtccaaaaat
     4261 tcttagacta catgatgaca gaagaaatcc aagaaggacc tgtcaaagaa ttgggctatt
     4321 taccaatcac aatgatggaa gtagaacgtg atcacgaagg aaatatcaaa taactagcag
     4381 ataaacatgc cacggtagtc gttactatta aggaaaaatc aactatgttt cccacatata
     4441 catttttcct ttaattgtga aaaatagttc ctcatatttt gccgtttttt gagctaatac
     4501 cgagggtcag ctgattaaac accgtttatt cgaaaaaaag agctacgaca tagaactgtc
     4561 gtagctcttt ttttgctata tgacaggaat gaaaggtgtt tgcaagctta atgtgaggaa
     4621 cactttccat atctgttcta tactggatag gagaagtttg gaaatatcca gaaaacgaaa
     4681 tcaatcgagg tagccacatg aagaataaat ggataaatcg aagtaaaaaa aagaaagtaa
     4741 cacaaagatc atcagataaa gtcatccgtc tttttccatc gtataaagaa ggattaacgg
     4801 cagatcaagt caaggaacga atagaaaaag gtgcagcaaa taattcagtc gatcccacat
     4861 tcaaaacaaa tcagcaaatc gtattggaaa acatatttac gtatttcaat ttgatctttc
     4921 ttatcttagc cattttgctt tgtttagtag aatcctataa gaacttgact tttttaccag
     4981 ttatcatagc caatacagga atcgccattt ttcaggaaat tcgatccaaa aagatcttgg
     5041 acgaactaaa tgttttaaat acagcaaaag tcaatgtcat acgggacggg atagaacaaa
     5101 caatagatat agaagacctt gtaatagatg acattgttat tttagagact ggacatcaaa
     5161 ttccagcaga tgcagaggtc gtggaaggaa aactgcaagt taatgaggct ttattgacag
     5221 gcgaagcaga tgaaataacc aaagaaatag gcgatccatt aatgtccggc agtttcattg
     5281 tttccggaaa agcttacgcc cgattagaca aagttggagc agattcgtat atttcccagc
     5341 tgacagtcaa agccaagaca atgggagaag gagaacagtc ggagatgatt gcttctctta
     5401 atcaattgat caaatggatt gggatcatca ttattcctat cggtatcctg cttttttctc
     5461 aaagttactt ttttaatgga aacacgatca aagaaagtgt cgttgcaatg gaagcagcat
     5521 tgatcggtat gatacctgaa ggactgtact tgctgacgac gattgcatta gcattaagtg
     5581 cgactaaact agcaaagcaa agagttcttt tacacaatat gaaaagcatt gagacattgg
     5641 caagggtaaa tgtcctttgt gtagataaaa caggaacgat cacagaaaat aaaatgtctg
     5701 ttcaaaaagt gatcgtctct aaaaaacaag aaataatcag tcagtcagat caattggaag
     5761 catgcattgc tgactatgca aaagcgatgg caggagacaa tgcaacaatg gaagctgtta
     5821 aagcatattt tacaaaaacc actgatcaat cctatcacca tgttattcct ttttcttctg
     5881 tccaaaaatt cagcagtgta gcgttggcag acaaggtgta tgttttagga gcgcccgaaa
     5941 tggttttgcg cgatcaattg ccggaatatg cggaagagtt tgtttctttc gctgaaaaag
     6001 gctatcgcgt gttggtcttt ggtgtgtacg atgggattct tgaagaacca gtattgacag
     6061 aagcagtcac accattaggc tatattctga ttgctaatcc tatcagaaaa gaagcaagag
     6121 ccacatttga ttacttcaaa aaacagcaag tagccatcaa agtgatttct ggagataatc
     6181 cgctcaccgt atccaatgta gctgtccaag cagggatttc acatgctgat cagtacgttg
     6241 atgcatctaa attatcagaa gaagaatatg aagcagctgt cgaaaaatat acagtttttg
     6301 gacgcgtcaa gccagaacaa aagaaaatct tcgttcaatt gataaagcgt aacaatacag
     6361 tagctatgac aggtgatggc gtgaatgata ttctagccat gaaagaagca gactgcagta
     6421 tagcgatggc ttccggaaat gaagccgcca tgcaggcctc acaagtggtc ttacttgatt
     6481 ctgacttttc acgcatgcca gaagttgttg cagaaggacg gcgcgttgtg aacaatattg
     6541 agcgatcagc cagcttgttt ttagtgaaga atattttctc ctttttgctc tcactgtttt
     6601 cagtgatctt tgctctgacc tatcctttag aaccatcaca aatcacattg attagtttgt
     6661 ttactatcgg acttccatct ttcttgcttg ctctagaaga aaacaaaaag cgaatcagag
     6721 ggaaattcat catgaatgtg atggaaaaag ctgtgccagg tggactaaca gatatgatcg
     6781 tagtcggtgc gttggtgatc tgcggggtga ctttgaatct aaataaaaca gatgtttcta
     6841 cagcatctac catgcttttg attgcagtag ggttcctcgt tctctataaa atctgttcac
     6901 cgctgaataa attcagaagt cagatcattc ttttctgtgc tagcggtaac tttttttcgg
     6961 tcatcttttt gcataagctg ttttcaatca ccggtatctc agctgtatca cttttgctgt
     7021 tgagcattct atttttctcg gcagattcga tttttaggca tttgaccaca ttggtagaat
     7081 atttgtttga acgtaaaaat gaaaaagagc aaaagccgtt tagtcgcgta gctaaaaaat
     7141 ttctatcgat atttaaacga gaaaattgac gaaaagtatc tcaaaaaaga gtaaaaaaga
     7201 acaaccactc gtgtatcttt cgaagcagga tgagtcatcc aactttaaaa cgcacgagca
     7261 gttgctcttt tttacatttt cggaatggta acggtgaaag tcgaacctgt tccaagatga
     7321 ctgtctacag taatcgtacc attaaggagt tgcacgtagt cttttacaat cgctaaccct
     7381 aatccggtcc cgcctgaatg tcggcttcgc gccttgtcta cgcggtaaaa acgctcaaag
     7441 atccgttcct gatcctcaat gtcgatacct ataccaaagt cttggacaga aaacgataga
     7501 tcatctgttg cctgatagcg gataataatc tcgctgtcgc tttttgaata ttggacagca
     7561 ttttcaatca gatttttgat aattggataa aggatatctg ttttagtagt aaatggttcg
     7621 ttctttccaa tcaatcgaat cgtcaaccgt ttcttttcga tgattggctg ataattttga
     7681 acgatttgct ggaaataagg ttctgtataa attgtctgga tctcgtaaga attctcgcca
     7741 tcttttgaca gctggatgat ttcccgaatc agtttatcta accggatcgc atctttttgc
     7801 atgatctcaa gaaaagaagt cagagtttgc gggtcatctt ttgcaccatc cagtaaagtc
     7861 tcggtaaaac caatcagtga agtcacagga gtttttaatt cgtgagagac gttgccaacg
     7921 aaatcctttt gtagcttttc taaacgtcgc actttcgtta agtcatacgc cacccctaga
     7981 atctgtccgg taccttctga attagtaaag tagcgcaaac tcaagtctaa tgtctgccga
     8041 ccttctgtaa gggtgatctc ctgatggatc agcggatgct caggagtcac ttgatgaatc
     8101 agctgaatga gttttggctc ttgaatgact tctgtgtacc gctgttcagg ttgatagctt
     8161 accacgttta aatgtagctg catctttgga ttaagcagta gtaaacgaga atcagcatca
     8221 tcaatcagga atacgccaat catcagttcg ttcagtaacg tatataattg ctcttctgtg
     8281 gtagtacacg cccgatacat cttactcatt tgttcgctca acgcattaat cgtctgatac
     8341 aattcttccc attgatcggg tgtttgcatg attacttccg cctgattagg attttgcacc
     8401 atttttttta gtacgggcag cacggttttc aatggctggt ttttttgata gatcagataa
     8461 tagatcattc ctgcaagaac aaggaagaaa gacagaaaga agaaaaagac ccaacggcga
     8521 aaactctcag ttctcggtaa aaaaccgctt gtcggttctg cgatacgtaa aatggcttct
     8581 aactggccac tttttttgac tggtaatgcg acatataaaa gatcctcatt caaagtagta
     8641 cttttgcgca aagcgctacc taggttccca ccattcaata cggctttgat ttcgggacgg
     8701 gagtttcgct gttcattcaa tgtttcattg tttgtgtcaa ataagatctt tccagtagca
     8761 tccattaaag taatccgttc gttcgactga tggacgaatt cttccaaagc agttttgttt
     8821 tgcgctgctt ggaggttttc gacatctaat tgccggatca gcagttgtgc tttttttgtc
     8881 aggtagcttt cttgctgttc cacgatctgc tgttgaaaat aatgggaaat caattgccag
     8941 ccaccaaaaa acaaactaac taaaagaata agaaagaaga gacgttcata aatttttttc
     9001 catttcatcg tttgggttcc tgaaacttat agccaaatcc tctaatagtc accaagtact
     9061 ttgggtgttt tggatctcgc tcgatttttt ctcgcaaatg actaacgtgt acatctacga
     9121 ttcggctttg tcctgcgaag tcaaaattcc aaatgcggtc tagcaatgtg tctcggtcga
     9181 tcacacggtc ttttcgtttc atgaaataaa caagtaattc aaattctttc ggtgttagtt
     9241 caatcagatg gtcgtctacg gtcacttgat aattggtcaa atcagcagtg atttgtccaa
     9301 tcgatagata ttcaggctca gcttcatctt ttgattgctt acgaggttca attcgtctga
     9361 atattgcttt catacgggct aatacttcgc gaggactaaa tggtttggtc aaatagtcgt
     9421 cagcacctat ttctaggcca atgatccgat ccacttggtc atctttagcc gtcagcatca
     9481 aaatcggtgt ttcatttttt tcttgacgca gccgctgagt gatctccatg ccatccatcg
     9541 ttggaagcat cacatctaaa atgatgaaat caaatgattg ttctaatgct aattctaatc
     9601 cttcgcctcc atctgtggca ctggttacct tgtagccttc tttttccaaa ttgaacgtca
     9661 agagcgttac aatagaaggt tcatcatcaa caactagtat ttttttcatt caaatctcct
     9721 ttaaataggt ttcattctgt ttatatttta gcatagaatc agtacaaagg gctattttac
     9781 aaaagaaata aatggtataa taggaaggca ctttgctgaa tagaaaggaa gagcagtcaa
     9841 tgattggaat cagtgcatgt ttaggcggtc tggcctgtcg ctatgatgga cagaaaaaag
     9901 aagtaccaga attgatggaa ctagttgaaa ctggagaagc tgtcatggtc tgtccagaag
     9961 tgatcggcgg attaccaatt cctagagatc ccgctgaaat cattggtgga aatggattcg
    10021 atgtgtggaa agatcaagca aaagtatgga cgacaagcgg cgaagatgta acggaagcgt
    10081 acaaaaatgg cgcgatcaaa gcctatcaaa aattgcagga aaaacacatt gatctagtca
    10141 tcatgaagga aaaaagccct tcatgcggaa cccattcgat ttatgacgga agtttttccg
    10201 gaataaaaaa aaatggtgcc ggagtggcta ctgcttattt tattcagcaa aaaatgactg
    10261 tgctctctga tgaagaatgg ctgaaaacta gaggtgagca gaatggaaat cgaaaagacc
    10321 aatcgaatga acgcgctctt tgaattttat tcgaccttat tgacagaaaa acaaatgaac
    10381 tacatggaat tatattatgc agatgatttt tcattaggtg agatcgcgga agaatacgaa
    10441 gtaagccgac aagcagtata tgacaatatc aagcggacaa gcaagatctt ggaggattat
    10501 gaaaaaaaac tccatctttt ttctaattat attgttcgag aacaggtatt ggaaaatatg
    10561 actgcatata ttacagataa gtacccggaa gataaaaaac tacttgaata tgtacagcaa
    10621 attcaagcaa tcgaagaata aataaaagga atgaagaaaa tatggcattt gaaagcttaa
    10681 ctgaacgtct ccagcaggcg atgggaaaaa taagaaaaaa aggaaaagta tcagaagctg
    10741 acgtaaaaga aatgatgcgg gaaatccgcc ttgccttact agaagccgat gttaacttgc
    10801 aagtagtcaa agattttact aagcgcgtac gcgaacgtgc ggtaggggca gaagtgctgg
    10861 aaagtttatc acctgcacaa caaatcgtaa aaatcgttga tgaagaattg acgatcacac
    10921 ttggttctga aacagcagag ttaaataaat caccaaaaat accaactgtt atcatgatgg
    10981 ctggtcttca aggggcaggt aaaacgacct ttactggtaa attagccaat tatttaaaga
    11041 aaaatgaaaa tgctcgtccg ctcctaatcg caggggacgt atatcgacca gctgcgatcg
    11101 accaattgaa agtattaggt caacagctag acgttcctgt atttgatatg ggaactgaag
    11161 tcagcccggt agagatcgtc cgtcaaggga tggagttagc aaaagaaaag aaaaacgact
    11221 atgtattgat cgatacggca ggacgtctgc atatcgatga aacattgatg gatgagttga
    11281 aacaaatcaa agaattgacg caaccaaatg agattttgct tgttgtcgat gccatgactg
    11341 gtcaagatgc cgtcaacgta gctgatagct tcaaccagca attaggtatt acaggggtcg
    11401 tcatcactaa acttgatggg gatactcgag gcggggcagc actatcgatc cgctcagtga
    11461 caggcgcacc aatcaaattc atcggttctg gtgaaaaatt gactgactta gaagtattcc
    11521 acccagatcg tatggctagc cgtatccttg gtatggggga tatgctgaca ttgattgaaa
    11581 aagcgcagca agactacgac gagaaaaaag cggaagaact tgcacagaaa atgcgggaaa
    11641 attcattcga tttcaatgac tttattgaac agcttgatca agtgatgggt atgggcccac
    11701 tggaagatct aatcaaaatg atcccaggaa tgaatcaagt ccctggaatc gaaaacgtca
    11761 aggtagatcc aaaagatgtt gaacgcaaaa aagcgatggt ttattctatg acgccagcag
    11821 aaagagcaaa tcctgatctg ttgaacccaa gccgtcgtcg ccgaattgct gccggttctg
    11881 gaaacagtgt tgttgaagtg aatcgaatga tcaaacaatt caaggaatca agaaaaatga
    11941 tgcagcaaat gtccaaaggg gatatgaaca tcccaggtat ggaccaaatg tttggttcag
    12001 gcgtcaaagg aaaactaggc aaaatggcga tgaatcgaat gatcaagaaa aataagaaga
    12061 aaaagaaaaa acggaaataa gatgaaaaaa acagcttcgg tacagactga aaatgtctac
    12121 tgccggagct tttctatcag caatttttat tctttactaa tacaattact ctaaacgaag
    12181 aggtggcaca gatgagatgt ccgtggagtg aacaaacaga aagtatgcgg caatatcatg
    12241 atactgtctg gggtgttcct gaatatgatg accaaaagct gttccgaaaa ttgatgcttg
    12301 atattaatca agccggattg agctggcaga cgattttaaa taaaagtgaa gcattcgatg
    12361 aagcatatga tcgattcgat atcaaaaaag tcgcaaatta tggagaaaca aaaatcagtg
    12421 aactaatgga aaacaaagga attattcgta accgaagaaa aatcgaagca gccgtccaaa
    12481 acgccaaagc agtcttgaaa attcaagaag aaatcggcag tttttcagag tatctttggt
    12541 cgttttctaa tggaaaaatc gttgattctt cttatcattc acaagaagaa gtcccaacaa
    12601 caagtcctct ttcagatgaa ttagcaaaag atctaaagaa aagaggattt aaatttatcg
    12661 gaagcacaac aatctatgct tttttagaag ctgtcgggat catcaatgat caccttgaca
    12721 gttgtttccg caaagaagag gtcgtacgta tcggcagaaa gggcgaataa agcatgcgaa
    12781 aaatcatatt ttatggtgct ataagtttag atggctattt ggcaacgaaa acggatgatc
    12841 ttcaatggct ttttgacact ccaacaggta agcaaactac ttatgaagct ttttatgaaa
    12901 caatcgatac gaccatcatg ggcagaaaaa cttatcagga agcaaaaaaa tatttggaga
    12961 ccgaagcaat ttatccagag aaaaagaatt tcgttttttc cacccacgca caattacaat
    13021 tgccagatgc tgaggtcgta aacgaagatc ctgttgcttt tctaaaaaat ctacaaatga
    13081 cagaaggaaa agatatctgg gttgtgggtg gcggtcgatt gatcaaaccg ctattggaac
    13141 atcaaatgat tgatgaatgg tatatccaga ttacccctgt attattaggg gacgggattc
    13201 ctttattcca aaaaggaaca tatgaagcgc gttttgaaat gctagacacg acacgattcg
    13261 gtgaatttat cgaattgcat tatgtacgaa agtagaagta aataaaataa aaaaggcaac
    13321 tatatgcaga aatgtcctgt acatagttgc cttttttatt accgttatgc tttttactct
    13381 gttaatttgt tagaaaaatc tagatacgca tctaaaatcg tttggaagaa acttaatgtt
    13441 ccttcaacga tattaccatt ttcatcaatt agattcgcaa cgtttccgat atatgcttcc
    13501 ggttgctgca aggttggcac attcaaaaag acaagtgatt ggcgtagatg gtggtttgcg
    13561 ccaaagccgc cgatcccacc tggtgatgca gtaacgacta aacctggttt atgatcccaa
    13621 acactgtgtc cataaggtct tgagcctaca tctaaagcat ttttcaatac tgctggcaca
    13681 gaacggttgt attcaggagt aacgaaaacg acaccgtcta gtcccctcac ttcctcacga
    13741 aaacgagtcc attcagcagg agcctgttct ggagtttcga gatcctcatt gtaaaatggc
    13801 agatcatcga tttttacaaa tacactttcg tacccttcag gaagcaattt cgcaaaagct
    13861 tctgctactt ttttgttgta agaatctttt cttaaactac caataaaaaa tccaattttt
    13921 tttgtcatac gatttttcct ccttcaaact atctataata atcttacaaa agataagtaa
    13981 ctggagcaaa taaaaacact tactgacaaa agctacatag aagatagatt acttattttt
    14041 aacaaaaaag aagtctaaaa tcttctattt tctaaaaaaa atcgaattta atcaagctgt
    14101 aaagaaaaaa agctttacag ggtaaaaaaa aactgttaca ctacatcttg tgaataaaac
    14161 aatggaggtg gaaataaata atggcagtta aaatccgttt aaaacgtatg ggttctaaaa
    14221 agagtccgtt ttaccgtatc gtcgtagctg attcacgttc tcctcgtgat ggacgtttca
    14281 tcgaaactgt aggtacttac aatcctttga aagaccctgc agaagtagtt ttaaaagaag
    14341 acttagttct tgactggtta tcaaaaggtg cacaaccttc tgacactgta cgtaacatcc
    14401 tttcaaaaga aggcgttatg caaaaacacc acgaagctaa attctcaaag aaataaggtg
    14461 accggatatg aaagatttaa gcgacttagt cttaacaatc gttcgtccgc tagtcactta
    14521 tcctgatcaa gtcaagttag acgtcgtaga gtcgaaagac ttttacgagt acaatctaac
    14581 agtggctcct gaagatattg gccgtatcat tggaaaacaa gggcgtgttg ctaaagcaat
    14641 ccgcacaatc gtttacggtg ttcggatcaa tgcaccgaaa aaagtgcgtt tgaatatcat
    14701 cgatgataag gaaaagtaaa taaacgtgct gtactcgaat tttcgagtgc agcttttttg
    14761 ttttttttat taattgaaga aatgattatt tggcaaaaca agcaagaaag cgtatcctta
    14821 taggaggagg gagtgaacag ccaatgagaa agaaaatgtt atttattcca tttgctctat
    14881 tgttaagcgc ttgtagttcg gttactcaag aatcagacaa tacacatcta tcaagcagta
    14941 tatctgaaac tgttaccagt ccagaaaaaa gtagtaccaa aacggcttcc accactgaac
    15001 aaacaatggc tacctcaaat aatgagaaaa agactgcttt agaccagttg aaagaacaac
    15061 agccaaatgt tcccatgcct ctagatgtac cagtctcttc aggctatctc aatatcgcag
    15121 cgacacatac aaagcaaggt tattctattt tatattacag aacagatcgt cccctcgggt
    15181 tgaatgctga cgaattgaat caagaaacgc ctattgcaac ctatctatat caatatgggt
    15241 ttgcttctag tcaagaaaca atccaagttt tgcagccatt tgagatcgac acaaatggtc
    15301 agcaagtgga cttaggttct cgaatcacag ggtatcagca aggtgcagca ggttcaagtt
    15361 ttcttgaatg gcaagaagga aactggcgta ttcgaatccg tgggaataat atagaaggcc
    15421 aagatccctt actattagct aaagaaatcg tagcttattt ggaagaaaac agtctaccag
    15481 cacctgaaca atttggtaaa attactgttg atatgggtga tacgacgaat cgagccgtag
    15541 aagtaagctg gcaagaaccg aaaaatgcct atacgatcac tcatcaagat cctatgtctg
    15601 cgttgaagat ggcagtttct atgaagaggt tgtgaaatca gcgcgctgat ctgagcccat
    15661 catttaactc caagtcacag gaagtaatca aaaatagcac gccgcatttt tgcataattt
    15721 tggcttaata ccttaaaaga aaactagaat tgcctcttca cacatgctaa aataaaacag
    15781 acaaaaaaga aatggggata taagttgact gaatacttga atgtaggaaa aatcgtaaac
    15841 acacaaggta tcaaaggcga agtccgtgtt atctcaacaa cggatttccc agaagaacgt
    15901 tacaaaaaag gaacggtgct aacactattc caagacggaa aagcacctgt ggaattaaca
    15961 gtcaaaagtc atcgcaaaca taaaaatttt gacttattga gttttgaagg acatccttct
    16021 atcaatgatg tggaaaaata tcgggatggc atattaaaag tgtcaaaaga caactctgta
    16081 gatctagctg aaaatgaatt ctattaccat gagatcatcg gtctgcatgt attagaagat
    16141 ggaactgagt taggtaaagt aaaagaaatc ttgtcaccag gtgccaatga tgtttgggtc
    16201 gttcaacgtc cgaaaaaagc tgatatattg cttccatata tcgcttctgt cgtcaaagaa
    16261 gtcgatttag aagctggagt ggtccgtgta gaaattccag aaggactgat tgacgatgaa
    16321 gattgatgta ttgactttat ttccaagaat gtttgaaggt cctatggggg aatccatcat
    16381 cggtaaggct gtagataaag gattattaga tatcaatatc tctaacttcc gcgattattc
    16441 agataacaaa catcagacag tagatgatta tccatacggc ggtggagcag gtatgctgct
    16501 caaagtccag cccatctatg ataacatcca agccattgaa aaagctgcac cggatgtcaa
    16561 aaaaagagta attcttcttg acccagctgg taaacgattc gatcagaaaa tggcagaaga
    16621 attttcacaa gaagaacact tagtattcat ttgtggtcat tatgagggat atgatgaacg
    16681 tatccgcaca ttagtgacag atgaagtttc cttaggagat tatgtcctta ctgggggaga
    16741 attaggtgcg atggtcatga tcgatgcaac agttcggctt ttgccagatg tgttagggaa
    16801 tcagacttca gctcaaacgg attcttattc aaccggttta ttggaacatc cccaatatac
    16861 tcgcccggca gaatataaag ggatgaaagt accagaagta ttgacaaatg gaaatcataa
    16921 attgattgaa gaatggcaat taaaagaatc actaagaagg acctatcaac gtcggcctga
    16981 tcttttggaa acacttgaat ggacacctca aatgacgaaa tttttagaag aaatcaagaa
    17041 agaagaacaa gaaaaaacag cagatgaagc caagtgactt tttctaaaat cttctttaca
    17101 gtaggttgat aatatgttag tattttatgg tgagtgcaaa agcacttaac tattacgata
    17161 ttccgctgtg agaaaagctc ataagaatat ttggaataag gagaagaaaa ccatgaatcc
    17221 attaatcgaa gaattaacaa aagaacaatt acgttctgac atcccagcgt tccgccctgg
    17281 tgacactgtg cgtgttcacg caaaagttgt tgaaggtact cgtgaacgta tccagttatt
    17341 tgaaggtgtt gttatcaaac gccgcggtgc tggaatcagc gaaacttata cagtacgtaa
    17401 agtttctaac ggagtgggcg ttgaacgtac attcccattg catacaccac gtgttgcaaa
    17461 aatcgaagta gttcgctacg gtaaagtacg tcgtgcaaaa ttgtactacc tacgtgcatt
    17521 acacggaaaa gctgctcgta tcaaagaaat ccgtcgttaa tcattgttat cagactgaga
    17581 aagaaccctt ggtattcaag ggttcttttt tcttagcatg taatttgaac accctgatcc
    17641 agttttttct ttaattattg gtaggggaga ataatggatt agaataaatc tacctataag
    17701 tagtagtaaa aaaaagagca ctatgataat atctttctta agagtaaccg ctttaataaa
    17761 aaatccagaa tattctaaca taaatggagt attcttagaa tcaaaaggag aaagaagatg
    17821 gtttatactt atacggagca agaaaagatg aaagttttag acacattcat gaatgatgga
    17881 aaagtaaaac aagtaccaag ttcaacaaaa aagaaataca tcctattgaa agaagtcttg
    17941 aaacgctttg accatggagt gacttataca gaaacagagg ttaattcgat actgctgaac
    18001 gtattttcta gtggcgatta tgtcgaacaa agacgttatc taatcacatt tggctttttc
    18061 aaaagaagtt cagacggtcg ggcatatcag atgatgggaa ttgaaaatta gaagttttaa
    18121 tttatactca ttgaaaaaag ttcaagtatg cgatattggt tctacaccgc atacttgaac
    18181 tttttttgtc atctgtatct ataatacaaa gccaagaacg ttattcaaaa tatggatagc
    18241 tatgataaaa gctaatgagc gattcgcagt taaataagca atcgtcagta aaatcgttcc
    18301 aggagcgtac atgaaaaaat caattggatg cgttacatga ataaagataa ttctctttta
    18361 tttgtacgaa taaataccaa aacgtacctc ctaaaattag attttggaca gatgcccttt
    18421 aaaaagataa caagatttcg ttcttgaaac aatatatatg cttttattcc aatgaggttg
    18481 tgaaaacagt attttgtcct gagcgttaga aaattgaaaa tggggaatag caactcgtac
    18541 tttaccattt tttaagtgaa tacaagatca gctaattgaa caccgtttat tcgtgatgag
    18601 ggacacaaca ctgcagtcga cacatttctc ttttatgttc aaagataaca aatatttaaa
    18661 acaaagaaaa atagtagata atcccgtcct aactctttta ttcttccctc atagcttcca
    18721 aatttaagca atacttcaat taatcaagtt ttatcttttt ttttcaataa tcgtaaaaaa
    18781 agagtatttt ttatttaaaa ataaaatctt tgtattaaag gacaagacta aaataacctt
    18841 agaataaaaa gagaaaaaaa gccccaaact ttctatacat caataaaata ataaaaatta
    18901 aatttagaat aacgtgtaaa ggattatttg atgatttttt attgagagga gggatgaaaa
    18961 tgattaagaa aactcaaaat aaaatccaac gtatatgtca aaaacatttt gtttctagac
    19021 tcaaagctgt atctaaaaga aaatacttac atcccattat gatttcgatc atcttgattt
    19081 ttactttctt agggagctta tcaagtattt atgtaaacgt ttatacagaa acgtcaaatt
    19141 ttgctaacca aacgacagag gagacaaata gtccacccta ttctgaaata cagtccatag
    19201 aaagcaccaa tcagtctagc aacaacgaga caacctcaac cacatcctcg actcaactga
    19261 ttgatccgac agaaaaagaa atcacagcag caaaagcagc aggggagaaa gcttattcag
    19321 aaacaggtag aagccagaca tttagtactg ttgcggccac tgcgaatttc aacggacata
    19381 ccataccaga tggatataca gtgatatatg ccaaagatgg agtcattgtt gcggttaacg
    19441 gatcgatgag tgcggataaa actgcgttac aaggcgtaac caaagcaatc gcttttattg
    19501 ataaccgtcc agatatccat aatctgttta ttggctccac agtaaatggt actactatca
    19561 cattcccaaa aagtatctat atgggggtgg ctaccgctgg aaatacgatc gattcagtta
    19621 cacccaatgc ggataaaagt tattctttta caccctcaac atggggaggg cttcctgccg
    19681 gaggaggtat gagtactttt tcaatcggta tacagttagc aaatgatatt ccattcacgg
    19741 ggtactcgat caaaaatggg cagatcgttg atggtaaggg aaatgtttca aattttccaa
    19801 cctatcaagc agcaacggtt caggtcaatg cgaatcggac aggaactttt tcttatacag
    19861 tcaatggtgg agcagcaaaa atcggaacgt acgggactac attatctgga atccatgtgg
    19921 gtgacaaagt ggttatcact ccaacagcag taacgggcta ttcttttgca caaacaaacg
    19981 gttctttcac agccctagaa agtaacgtcg atacggtgac ctatacaggc aaacaaacac
    20041 caatcactat taagtatcaa gactattttg gacagatgat tgctccttct aaaataatga
    20101 atcttactta cggaagtgct gcacaagacc tgacgactaa tacgcctact atcaacggat
    20161 atacctttac agctgtttca gcgacagaaa caaagaacca atcagcaatg agtgttttag
    20221 ctagtttaga tacaaatgga aatgtaatcg taaaggacgc aaatggaaaa cagatttctg
    20281 aagtcatcct atattataag acaaatgcaa cagtatcaat caatgcaaat ggcagtaagt
    20341 actatgatgg tctttctgtt gtaccgatcg ttaaatatgc ctttaatgat aaaacagaat
    20401 caacatccct tttaaacaat gatctcagta ttgatcaaat cacatggaat ccaactgatt
    20461 tcaaagcgat gaatgaaaag ggagttgaag taactgcgcc tactgaaatt ggaacctata
    20521 cgtcttggca attgacaaaa agcggactag ctaaactagc tgccagaaca aactatttat
    20581 ttactatcgt gcagacatct gatgtctata cgattaagca aatcagcggt gcggtagagc
    20641 tcagtggcag taagacatat gatggaaaag caggtgtccc gtcaatccat gtcaagctag
    20701 cagagggtgt cactagttcg cttactccag tacaagtggc acttagcagt atggattaca
    20761 cagcagatgc acaatcagca aaaaatatgg ttaatgctgg cagctataca attaaactaa
    20821 cgaatagcgg aatagacaaa gtcaaagcag caaatcccaa gttgtcattt actgatatag
    20881 ccaacacatc aggaacttat accatctata aagctaacgc agtgattact gtcgatgacg
    20941 ctgcctttaa ttatgatgcc caaagtcact cgatttcggt tggaaatctc cacgttaccg
    21001 gtgttgtctt aggcgaatca ttggattata ccctaacagt taacagccgg acagatattg
    21061 gatcacaaat agtaacgatt agtttaggcg aaggaagtgt aaacaataat tatacgatta
    21121 tcgcaacaga taccgctaag ttgacgatca atccgactct cttgcttcct tcgacaggtg
    21181 ggataggtct actgcccttt gtctttttag gactgatctt tattttttct ggcttctttt
    21241 attttatcca tcgtaagaaa aaagcaggtg aacagcgatg aaaaaaacaa aaaatgtacg
    21301 tgtggatata tttgctgttc tcttttttat cctactggtc ttttttatag gttctccgac
    21361 tgtgtcagct agagaatcac ctattacatt tactttgcat aatcgaatgt tcgaaagcga
    21421 taagatgcca agtatcagtc aaaacgacgg aataaatatc ccggataact ttcaaggagt
    21481 aaaagggttg aacggcgtta ctttcgctat atatgatgtc tcggatgaat tttacaagct
    21541 gcggtcagaa ggaagtagtg tggaagacgc acaaagaaaa ctagcacaaa aaagtgatag
    21601 tgaaaaaata ctggcagaaa atgtgacaaa aacagtagac gaggaagagg gcattgcttc
    21661 ttttagtgca tcggacaaag atgagcaagg tcgtgacgct gtttaccgat ttgcggaaat
    21721 aaagacttca gattaagtaa aagaaaaatc agcaccattt gtcgttgtgc ttcctgtgac
    21781 agattcatct aatcataaat tgacgaccat ccacttgtat ccaaagagcg aacaaaaaat
    21841 acctgctgca ctcacattaa caaaaacagt agagaataag cagacagatt ttgcagatgg
    21901 ggataaagtt ccttatctca tcaccgtaac aattcctgag aacatcaacg agataggaac
    21961 ctatacgatc aaagatacag ctgatcctca gttatggcta gaaccagaaa cgatcgattt
    22021 tttgattggt ggagacaaga ttcatacatt tcacacacaa aaaacaaaac atggttttgt
    22081 cttatcagat tctggaaaag atcttagttc gtttgctggg aaaaaattaa cgatccgtta
    22141 ccaaatgaca ttgaaagaaa acagtgaaaa aacgacattt gataacgatg tacgtttgac
    22201 gactgacaat caaacagtag aaacacatct tgccatccaa acaggaggca aacaatttgt
    22261 caaagtggat cggcaaacga aacaaaaact agcagatgct caatttctag tcaaaaaaaa
    22321 tgaccaatac ttagcgcaag aaaacgggat aaatcattgg gtagccaaag atgattcaag
    22381 agcaacgatt tttacttcca gtaaagatgg aacattttct gtccatggat tgtcttttgg
    22441 aagttacgaa ctagtggaga ttaaaccgcc taaaggatat atattgagtc aatcaaccat
    22501 tctctttgaa gttgaaaaag gcagttatga tccgcttcat cctataccat tggaaatcat
    22561 caacgaacca aaagcaaatc cgacgaataa tggaaaaacg ccagttcaga tgcagacaaa
    22621 tggtccatca aatgaaaaaa atggaggaag ctttccaaaa acaagcgaag agatgcttgg
    22681 aggtttctca attttagggt tgttgctagt cctttcaaca gggacagctt ggttttataa
    22741 aaaacaacaa aaaggaaaca ataggaggga aataaaatga aaaacatcaa aacaaaaata
    22801 tggacgtttt taggaactgc tatcatgctg cttcctttcg ttctcggcct aggaactgca
    22861 gaggtttcta ggccgtatca cctacaccag aaaatgttac ggttaatttg cataaattga
    22921 aattcacttc agcaccagaa aatcaaataa acaacggaac ggaattgaca tttccgaata
    22981 gcgaaccgtt gaacggcgtt gaattcaacg tatatgacat cactgctacg tactatccaa
    23041 gtaaagacac agcagttcca gcagacgcta cacccttcgc aagtgtaacg acttctggtg
    23101 aaggattagc taacctgact cttccaggta aatctgatgg gaaagatgct gtatacgtct
    23161 ttgtagaaac accaaagccc ggtgtcgaaa cgtcgccaaa tatcgtgtta agcttaccct
    23221 tttataaccc gaattcatca gaccctgaca aacctttaga cacgattcac ctatatgcta
    23281 aaaatgtcat caaagaaagc aatatcaaaa tccagaaagc tgggaacttt tcaggggtag
    23341 ataagttagc aggggcgcaa ttccagatca aaaattcaga gaatcaattc gtgaccggtt
    23401 ttgatgaaaa cactggtgtc gctctctatg atcctgctga gtcagcgttg acattcacaa
    23461 ctgatactga aggatccatc agtgtcaatg gattaataga cggcaattat actttagttg
    23521 aaacaaaagc accagatggt tatcaattaa ccaatccaca aaaagaaact acttttatag
    23581 taaaaaacgg aaaattgcaa caaacaaccg gtatcatcca tggcgcagat gaagccaatc
    23641 ttgggaatcc aaacggtgta gtcaatcggg aaaatacaac tacggataac acgattactg
    23701 tagaaaatgt ccaaaactac ggtgatttcc acttcatcaa acaagatgtg aacacgcaag
    23761 aaaaattagc cgatgcagaa ttttctattc taagagcaaa agatccaact gttaaattaa
    23821 tgaaaaaaat agcaaatctt gcctcaggag aatacccata tgcttggtca gatgaagtca
    23881 caggttctga ctgggaagaa gtgaaattga tttctgattc agaagggaaa ttttcaatcg
    23941 aagggctgaa acaaggggca tactgccttc aagaaacaaa agcaccagaa ggctacgcat
    24001 tacctaagaa tgaagctgcg tacactgaat ttacagtaga tgatgatcca acaacttctg
    24061 atgaaacaac gatcgataac caacctaaag gaatcttgcc ttcaactggt ggtatgggga
    24121 tcatcgtatt catcttggta ggtactgctt tagttggagg agcagtgatc tacttcaaaa
    24181 aacgccatca agaaacagaa gcttaaacta ttggaaacaa aaatcatacg ataaataaac
    24241 gatagtgatt caaatgggga gaaaggttgt gacaagtggt cggtctcttg gtattcgctc
    24301 aacaaacggc aaaataggag gaactatttt gccgtttgtt gagcgaatac tcaggtcaag
    24361 gcgctgattt cacaacctct tcatatacat attagaaaat aggtggacat gatgaataaa
    24421 agcagaataa gaatactgga catcttcatg gcaatcattt tagtcgttgg gatcgggatc
    24481 ttttcttatc cttttgtaga agattcactg aatgattttc ttgcccagca aatgatcatc
    24541 cattatcaaa agcaagcatc gaataagaat tcagaggaaa taaaaaaaca gcaggaaaaa
    24601 atgacaaaga aaaaccaaca gttggcagag caaaacgtat caccagggat aggcagtttc
    24661 aaccaagcag ttgatgcaaa agcattaaaa gatttaccta gtaatgcctt ttttatggaa
    24721 catatgcttg gagtcatcga aatcccaaaa atcaatgtca gcttacctat attcgatcag
    24781 acaacggaaa tatttttgca aaaaggaacg tcattattgg aagaaagttc ttatccgact
    24841 ggcgggaaaa acacccatgc cgttctttct gggcatcgtg gactcccaga agcaaaatta
    24901 tttacagatt tgcctaagtt gaaaaaagga gaccagtttt tcatccagat caatggaaag
    24961 acattggcgt atcaagtaga aaaaatccaa gtggtcttac ctgatgaagt agattctttg
    25021 ggtatccaaa aaggcagaga tctcgtgact ttgcttacct gtactcctta tatggtcaat
    25081 acacatcgac tgcttgtgac ggggcatcgt attccttatc aagcaaaaga ggcaaaaaaa
    25141 gcgatccaag gaattgatca atggaaaaaa tggaaatttt ttatttggtt tatcggtata
    25201 ctacttggat caatcggctt agtttggcta ctcatcgctt atttagattc tttggccatc
    25261 gctaagcgaa actatccttt atctttttat gtaaagaaca caaacggacg accaatcgaa
    25321 ggaatggtct tttctgtaaa aacgctcaac ggcaaacact atattactag agaaaaagtt
    25381 ccatttgtga aagcttctga tgaatacgga ctagtgagat tttctgattt aaaaggcagg
    25441 aactatcgct tgcaacatga ggagctcctg cttaaaatcc atgtaaaaca taaacattcg
    25501 aaacagtttt caatgaaatt gaaaaaagga agatataaac tgcgaaaaga aaaagaggtg
    25561 tactatttga ttgagaaaga atgaatgaag atgtccaaaa aagcagaggg aacagactaa
    25621 atgaaaaaag agagaagctg acgaaatgga cgtgtaaact gctatttttg gtttactatc
    25681 tggaacgcca gcttctattt ttttatgttt cagaagaatt ttattattat agtataactt
    25741 ttgaattagt ttccataaca tttggagcaa ggggttaaac cacgagcttg agcttcgctt
    25801 aaagtggcag gggtatacgt accatttcca catttatgtg tatggtattt tgaaccggtc
    25861 ggtgtgacat agacagtttg ttcattattt tgctcaggag ctgcggcttg tgcctgctga
    25921 gaggcctgtt cagctgctgc ttgctgtcgc gcctgttctg cttgttgctg tgcgattgct
    25981 tcttgttgcg cttgttctgc ttgttgtcgt gcaatttctt cttgcttttt ccgttcttct
    26041 tctgcttctt ttgctttgat tgtggaatca attgcagcaa gacggcttgt caactcttgt
    26101 ttgttttcag gtagcgcttg gatagctgct gaagcagttg catagttttc ttttgtagga
    26161 tttgcttcag cttgtgacaa agcagattcc gcttctgtca cttttttttc tagtgcagct
    26221 ttttccgctt tttgtttctc ttcttctttt ttcttttcaa tttgttcttg ttctttcgat
    26281 gaatctgccg tactttcgga gatcgtggta ctgctgctgg aagcctgagc tgaacttgtg
    26341 ctttgagtag tagacgtagt agcaccacac ccactcaaca aacttcctgc gaccaaaaac
    26401 aatgcaacta attttttcac taaatttcct ccttaagtaa aaaacaaccg ttttcaataa
    26461 atgtcctttt caattgttta cttacttgtt ataataattg tgttatgaat agtgattgag
    26521 gaaacttaat ctaatcccgt tttgatacac gggatttttt gctatagttc tgttattaag
    26581 tatgcaataa taaaatatgt acgttatttt attattagat tattgacatt tatataataa
    26641 acgattaaat gattcatatc aatagaatac ttaggaaaaa aagagaaata ataacaggtt
    26701 tatgcactat tgacggtgtg acaatatgat atttgtatcc gttttttttc ttgtatgtag
    26761 tatagtaaag tagatacagg aggagaaaat atgcagactt ttttaacaaa agtttctcaa
    26821 aagaaaatta aaatgattca tttactgctt gaaacagaac gttggtgttc aatagaagaa
    26881 ctacaaaacg aattgaaggt atcaagtaag tctatcttga attatctaac agatttagaa
    26941 gaattgttcc aaaaatatcc tgataaggtc attttgaaga atgagaataa tcggcgcttt
    27001 tctatggaaa agcaggagaa cttcccaatc tacattattt atcttcattt ctacagaaaa
    27061 tcatataatt atcatttgat tgaattcatg tatcaacatc ctgagaaaaa tttggaagat
    27121 tatgcagacg ctcaatatac gagtgtatcc acagtttttc gttatgctaa gttattagta
    27181 aagtactttg aaatgacgga cgtcaaagaa tagtagccgc cagatagaag gaaattagca
    27241 gttgaaaaag ctgccctgca tcaagtaata cgaccagcca aacggaaaca gtgtctcatg
    27301 tttttgattt ggctggtctt attaccgcag atgcaagctt ttgccacacc tctttcttgt
    27361 catttacaga ctcaactatc aatgctgcaa gctttccctt aatgctgtaa caccagtaag
    27421 agttgtcaag accagcagac tgactaggta aataccgctc aaaaacaaga ttacggcagt
    27481 taaactataa tgatccatca agaaaccgat gacgatagaa gaaaaaccac caacagctcg
    27541 tccaaggttc ataatgaaat tattcgccgt cgcgcggatt tctgttggat acaaactact
    27601 aatcactgcg ccatatccac catacatgcc attgataaag tagccgacta tcacagcggc
    27661 tgctaccaaa ctccactggc tatgggctaa cacaagtaga tagacagata aggatgaaca
    27721 aattaaaaac aaagaaaagg ctagtttagg ccccaattta tccatgatta tgccaaaagt
    27781 catcatcccc aaagacatgc ctaaaatagt actgaccatc cacaatgaag acccagaaac
    27841 cgaaagccct aatcgatttt gcataattga aggcagccaa ttcattaacc caaaatagcc
    27901 ggcaatttgg acagttacca tgatactaag gccacatgtt tgccaagcaa gatgttttga
    27961 ttcaaacagt ctgctaagtt tggttttctt ttcggcagat tgtacagatt tgaattcctt
    28021 tggttcagtc aagccgcgac gaatgaacaa gaccatcaac accggcagta cacctacgac
    28081 atacaacatc ttccaaccaa acgttggaat gatcacagca gctaaaatcg cagccaaagc
    28141 cgcaccgacc tgcgcaccaa taccagcaac cgaagaagct cgtccaattt gtttttttga
    28201 aaaactttcg gaaatcaagg acatacacgc cccgtattct cctcccgctc ctacacctgc
    28261 gataaagcga aagagataaa ccaagtagat gtttgaagca aaatacatca ataaagaagc
    28321 aatcgaaaac agaaggaccg tttgagaaaa tactttcaca cgtccatatt tatcagctat
    28381 gatgccaaaa aaaatacctc caatgagcat ccccaaatta gtgatcgttg aaatgaaacc
    28441 cgcttgcgta ccactaatat gaaaagaagt aatcattgaa gataatgaaa aagctaaaaa
    28501 cataatatcc atattctcta aagcaattcc cgccgatgtc gataataata actttcgctg
    28561 atacgttgtc atttttatac cccttttcct aaaatttccc taaattgtta aaagtatatc
    28621 caaaaaagaa taaaaaaaca agactttttt atttgaaata atacacaaac aaccgatata
    28681 gataatccag cttagtttta atagaaatga gtattgactt ggagtacact taaagttgta
    28741 gaataaataa aatacataag taaagtggca agaaattaag agaaagagtg atcagatgaa
    28801 tatcaaacaa gtcagtgaag aaaagggcat ttcggccgat acattgcgct attatgaacg
    28861 aatcgggttg attccaccag ttaatcggac aaaaggcgga atccgtgatt atacagaaga
    28921 agacctaaaa tgggtcgact ttacgatctg tatgcgaaat gccggattat cgatcgagtc
    28981 tttgattgaa tatattcgcc tatctagcga aggagaagca actgtatttg agcggcgtaa
    29041 gcttttgatt gaagaaagtg aacttttgac gaaaaaaatt gctgaaatgc aagaatgttt
    29101 ggaacgttta caaggaaaaa tcaagaaata tgatcgtgtg ttatctagaa ataaaatgga
    29161 atgtatcaag taaaaaaatc aaggagcatc gctatggagt tacgcttact aaaatatttt
    29221 tggacaattg cagaagaagg aacaatctct caagccgcag aagttctaca tcttacacaa
    29281 ccaaccttaa gccgacaact gaaggagtta gaagaggaac taggaacaga actgtttgta
    29341 cgcgaaaacc gcaaaatgat cttgacagaa gcaggttatt ttctaaaaaa gccgagcaga
    29401 agaaatttta gatttaacga atcaaaccac tcaagaattc gagaacagaa aaaaacaatt
    29461 attcagcggc cgatttacga tcggctgtgt ggaagctgat aattcgaata cattggcact
    29521 attactagaa aagttgatcc gtgattatcc cagcgttcaa tttcatatcc acagcggaac
    29581 aagtgatgat atcacggagt gactagaaaa aagcctgtta gatttagcga ttttgctaga
    29641 tccagtagat acagagaaat acgaaacgat tttgttacca agaaaggaaa aatggggatt
    29701 gctcatttta gaaaattctg ttttagcaaa aaaagacgtg ataacaaaag aagactttgc
    29761 gaatgtacct cttttgatct caaagcgtcc agaaatacag cgaatgtttg ctgactggtt
    29821 aggcataaaa aaggagcagt tgctgatcac aggaacgtac aatttgattt tcaatgtatt
    29881 tgcgctaatt gagaatcagg taggtgctgc tttagtcata gaaggtgctg taagtcatct
    29941 ttcaaagcga gtgacattcg ttccgcttga cccaatgatt gaaacgaact gcatgctagt
    30001 ctggaaaaag aatcggattt tatcacctgt agtcaatgaa ttgattcacc gtttcaaaga
    30061 agcttttgaa cagtaataag tatctctaat cgaagaaatt tcaatacaaa agcgagacgt
    30121 atgacagtct tgcttttgta ttttttcatt tttaaatcaa aaaaaataaa gagatttaca
    30181 taacttgtta aataagcgct tacaaacata agaagaacgg aaatgaatca gctataataa
    30241 ccgttgttct ggattgtaat cattacaaag aaatgaagat tataactttg gaggtgttcg
    30301 aaatgaaaga aaaaaagcaa aaattcgttc aaaaaacatg ccctttattc aatggttggg
    30361 tatgattctg ctgattgtat tagctttatt gacgatcatt ccttttttat ggatggtttc
    30421 tgcttcattc aaagcaaata atgaagtgtt cacgattccg attcaatgga tccctaaaac
    30481 ttggcattta gagaattatc tggttatttg gtctcgtatt cctttagtga cattttttaa
    30541 gaatacagct tttttaagcg ttgtgatcac gttgattcag ttgtttactt ctagttttgc
    30601 tgcttacggg ttttctaaac taaattttaa agggcgcgat attttatttt tagcatatat
    30661 cggcacgatt gctgtccctt ggcagtctta tatgatcccg cagttcatta tgatgagaaa
    30721 agtgggttta acatatacgt tgtggtcgtt ggtgctatta caagcgttca atgcttttgg
    30781 tgtgttcttg ttgaagcaat actacagtag tatcccagat tctttatgtg agagtgcgcg
    30841 gatcgatggc ttatcagagt ggggaatcta tcgcaagatc attttacctc ttacaaaacc
    30901 ggcgattgcc agtttgacga tcatcacatt cgttaataca tggaacgatt atatggggcc
    30961 attcatttat ttgtcttcta cggaaaataa aacaatccag ttagggttga aaatgtttat
    31021 tgggctattt gatgcagagt acgcattaat catggctgcc tcagttgttt ctgttcttcc
    31081 tgttgctttt atatttttag cgatgcaaaa atattttgta gaagggatcg cttcatcagg
    31141 aatgaaggaa taggaggtga ttatgaaaga gcagcgtttt gacaaaaatg tttatatgga
    31201 attcttttat tggttgtatc aatcattggc aagtagcctt tgtttttggt gtgtcaatat
    31261 cttgtatata gcagctgcgt tccttttgtc gatagatgga aggaatgtct tttcctttat
    31321 tttttcttta ctttttattg gtccaggttg catcgtgatg ataggtatga cagaagaatt
    31381 agcaaaagaa aaaagttttt caccagtacg tttgttcata aagacgtttc gccaattttg
    31441 gctaaaggga tttttttatt ggctatttgc ttggatagtt agtgtgataa tgatttttga
    31501 ttgtttcttt tttatacgtt tttcttatgg aaaatggttg attccgttgt ttgttttact
    31561 tgcttgttta tcagtttcct ttagcatcaa ctactggtat tttcaggtga gaaatccagc
    31621 gtcgaaacca aatcaagttc tacggatagc gttctactat acgttgaaaa aatggtatgt
    31681 gagtttacta gattttttac tattgacaag tttgtttctc ttctttttcg taaagcccca
    31741 atggtgtatt ctactaggtc cttctatcgt atttggtttg atttacttca acaatcgtaa
    31801 attgatgaga actatggatc tgtagacttt ataaattgaa actttcaatt aagaatgaca
    31861 gtttttatgt aaaaactgtc attctttttc attttttgaa acatatggct aaacaaatga
    31921 aataaaacgt gctatacttt tgaatgaaac aggtttagaa actgtatcaa ttatttgtga
    31981 ttatttctaa ctaataatta aaaataaagc ataaaaagga cgatgttcaa tggacgaaaa
    32041 aatgaaacaa ggttcgaaat ctgtagtaga aagtttgatt aatcatcatg ttgattatgt
    32101 attcggtata ccaggtgcaa aaatcgatgg tgtatttaat gaattagagg atcaaggtcc
    32161 tgaattaatc gtgactcgtc acgaacaaaa tgctgcattt atggcacaag caatcggacg
    32221 tattacagga gagccaggag tagttatcgc aacaagtggt cctggtgcta gtaacttagc
    32281 tacaggtttg gtaacagcga cagcagaagg tgacccagtt ttagcaattg ccggacaagt
    32341 aaaacgaagc gatctattga agttgaccca tcaaagcatg gataatgcag cactgttcca
    32401 gccaatcaca aaatacagtg cagaaatcca agatccagaa acaatttcag aagtgattgc
    32461 caatgcttat cgtatggcta agagttcaaa aaaaggcgcg agctttatca gtatcccgca
    32521 agatgtagtg gatgcacctg tccaagggaa tgtcatcaag ccattgagcg atcctaaatt
    32581 aggttctgct tctgcagatg atatccgtta cctagctgaa cgcattagag aagcaaaact
    32641 accggtacta ttagtaggta tgcgaggatc aagtgaaaaa gaaacgttag ccatcaggca
    32701 attagttgga aagacagcat tgcctgttgt agagacattc caagcagctg gagtgatctc
    32761 acgtgaatta gaagcgcatt tctttggtcg tgtgggttta tttagaaacc aaccaggaga
    32821 tatgcttttg aaacgaagtg atctagttat tgctattggc tatgatccaa tcgaatatga
    32881 agcaagaaac tggaatgcgg aaaaagatgc gcggatcatt gtgatcgatg aagcgccagc
    32941 tgaaatcgat ccttttatgc agcctgaaag agaattgatc ggtgatatct cagccactct
    33001 tgatttattg acaggttcat tagagcctca acaagtgtca gaagatgcaa aagaatattt
    33061 agcatctctt caagcagaat taacggagcg ggacattgtt caatcaaaag gagaagcagg
    33121 tatcttgcat cctttagaag ttattaacac gcttcagtca aaagtaacag atgatatgac
    33181 tgttaccgta gatgtaggta gtcattatat ttggatggca cgccacttta gaagttatga
    33241 acctcgtcat ttgttattca gtaatggtat gcaaacgctt ggtgttgcat tgccatgggc
    33301 gatttctgct gcattggtgc gtccaaatac acaaatcgta tcagtttccg gcgatggggg
    33361 atttttattc tctgcccagg atttagaaac ggcggtacgt aaaaaattga atatcgttca
    33421 tttgatttgg aatgatggac actacaatat ggtagagttc caagaaaaaa tgaaatatca
    33481 gcgggcgtca ggtgtagact ttggtccagt tgattttgtg aaatatgcag aagcttttgg
    33541 cgctaaagga atccgagcta caagtgtaga ggaattagaa aaagctttag aagaaggatt
    33601 tgcgacagaa ggacccgtaa ttattgatat tccgattgat taccgtgata atgagaaatt
    33661 gggagaaaca atcttaccag atcaattcta ttaaggaagt gtcgacatga ctgaaaaaat
    33721 cttataccag cacgggacat taggagcttt gatggctggc ttgatggatg gaacagaaac
    33781 gattgctcat atattagaaa aaggaactct gggattggga acattgcatg ggcttgatgg
    33841 tgaagtcatc tttttagatg gcgtagctta tcaaggaaga tcagatggct cagttgccca
    33901 attagatgga agtgaactta ccccctatgc agcaattaca gattttacgc cagatactag
    33961 tttttctgtc tcaaaaactg cagatggaga acaattgaaa aaagacatat tagtaagaga
    34021 agccggggaa aacctatttt tggcagtgaa gataactgga ttattcaaaa atatgcacat
    34081 ccgtatcatg ccgaagcaag aaaaacctta cagaagacta gcaaaaattt cagagtctca
    34141 accagaattc caacaaagca atgtccaagg aacattagtc gggttcttta cgcctgaatt
    34201 attccaagga gttgctgcag cgggatttca cctgcatttt atcgatgata cacatacatt
    34261 tggcggacat gtaatggatt ttgaagtggc tgaaggaaaa gttgagatta gccgcatctc
    34321 gtcccttgta cagcattttc cagttgatga tccgactttt gttcacgaaa cgattgatta
    34381 tgctgattta gcagcagaaa tccaacaagc agaatagaaa aagacagcga gatgcgttca
    34441 aggtgattaa cctgacgtat ctcgtttttt tgaggagaaa acctagcgtt tacaaaaaaa
    34501 ctgagctata atcttctcca tagatcaaaa aggagcggtt tttatcatgt ggacagaaaa
    34561 acagaaaaaa gatgcatacg aaattttatt attacagcaa caaggattat tagaagcaga
    34621 agataactgg ttagcaaatt tagcaaattc atctgcattg ttgaatgaga ctttgcctga
    34681 gactgtcttt gcaggatatt atttattcga tggtaatgaa ttgattttag gaccgttcca
    34741 agggcgagtt tcttgcacac gtatcaagat gggaaaagga gtttgtggag aatcagctga
    34801 aaaacaagaa acattgatcg ttgatgatgt caaaacccat gcaaattaca tttcctgcga
    34861 ttcagccgca caatcagaaa tcgtagtgcc aatggtaaaa gaaggtaatt taatcggtgt
    34921 tttagatatc gattgcggag taacgaaagg gtatgatgaa atcgatcaag catttctaga
    34981 aaaatatgta gatcttttat tagcaaattt taatataaat gctttttcat ttattaataa
    35041 ctaaaatcgt ctattgaaac aaaaaagaag agaaatcaag aataaaaaga gccggaaaga
    35101 cagtgggcat ttctgttttt cggttttttt atttttttat aaaatcacaa gtgttattga
    35161 ttttcataat catattttaa tgttattatc attttaaata atgaaaaaac attaaggatg
    35221 gatgaaatat gaataacgaa actatcattt taggaaaaaa atatatttgc caacctattg
    35281 gcttgaaaca aaaagtgatt ggagaagtaa tcagtaaatt agaaaattgt gttgtgatct
    35341 gcgtagacga atatcatgac gtcgatcgca atgaaatatt agaaaaatgc ggaaaagtag
    35401 tggcaaaata tactcacgtt tatgagttgg aaacaacaga atatctatat aactatagca
    35461 acaaatatga acatacttta gtttcataaa gatttaaata aagtgccttc aaaagcgaga
    35521 agaccaagct tttgaaggca ctttatttag ttggcagtga ttgttcatga tttttgattt
    35581 attcaaaagg ttcgcctaga gaatctgtct ctgtaacgag gcctggtgga gaaactcgat
    35641 aaaaacctat actgccagaa ctgtcctatt ttcggataga caaactagta gttttaaaaa
    35701 gatcatccga tccaatcatt tcaaaaaatg caaaactgat atcaggatca tttagctcag
    35761 gcttgttatc gtaaagcatt tgtaaaggtt gcatttagtt aggagtaaac gcgaaactat
    35821 catcattatt tgctgaagaa gatgaagaag ctaattcaga gtttgtttga aataaaggag
    35881 acgtgctgac agtttcttta ccctgttttt tgcagaggta gaaactttta tatcggaagt
    35941 ttctaccgga gaatttttct catttgtaga aattgttgaa tcgatactat tcgaaatttg
    36001 cgtatctgaa ggtatgttct ttgatgcaga agtcccacaa gcagtaagta acaataaatt
    36061 tgataaactg ataaacagaa ttcttttcat tatgtacaca ctccttatag tatcgtttag
    36121 catacaccta tgctcagtat taggcaaaat caatgcaaaa ctatcaagtc ttttatagta
    36181 tctattagtc ttagtaatac atatatggag agggtgatat cccagttcaa accagataca
    36241 ttggttacca tctgtattaa cgattatgcc tctaaacgct ttttttatga aaaaatttat
    36301 aagtgaaaac gtaggtatga tattatctag aggtaatttt tttgggtatt taaatagttg
    36361 ctaggaggat agcttttgga tttttacagt aattttatct taataatagc aatattatta
    36421 cttctaaata tttggttttt tgataagagt agaaatgcag ggataggttt tagaaccaaa
    36481 cgaagtacgt cttctgaaaa aaagtgggta tattcacaga ctatttttta cggaggggtt
    36541 atttcaatca gtttactttc ttcaacactt tattctttta atgttataga cgtttccatg
    36601 tcaaatttta tatctattat tggaatcctt atttctgcaa ttattacaca actacttctt
    36661 gtgtttgaag agaagtcaaa aaataattaa agcaattatg ccttttagta caggaattat
    36721 tacttcttac aaatgtatag cgaatgtgaa gcctgctgtt ttaattgttc tagaaaaact
    36781 tttgagtgaa caattatttt atgttaggat gaattaattt ctctagagtt tata
//
LOCUS       DAPBBR010000026        36821 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPBBR010000026 DAPBBR010000000
VERSION     DAPBBR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.026"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(23..388)
                     /locus_tag="RD488_001424"
     CDS             complement(23..388)
                     /locus_tag="RD488_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657507.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYAVCIIKRDK"
     gene            complement(563..2698)
                     /locus_tag="RD488_001425"
     CDS             complement(563..2698)
                     /locus_tag="RD488_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7657508.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2781..4436)
                     /locus_tag="RD488_001426"
     CDS             complement(2781..4436)
                     /locus_tag="RD488_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7657509.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4438..4752)
                     /locus_tag="RD488_001427"
     CDS             complement(4438..4752)
                     /locus_tag="RD488_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7657510.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4922..5182
                     /locus_tag="RD488_001428"
     CDS             4922..5182
                     /locus_tag="RD488_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDT7657511.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5196..5510
                     /locus_tag="RD488_001429"
     CDS             5196..5510
                     /locus_tag="RD488_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDT7657512.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5995..6549)
                     /locus_tag="RD488_001430"
     CDS             complement(5995..6549)
                     /locus_tag="RD488_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDT7657513.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6675..8603)
                     /locus_tag="RD488_001431"
     CDS             complement(6675..8603)
                     /locus_tag="RD488_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDT7657514.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8909..9625)
                     /locus_tag="RD488_001432"
     CDS             complement(8909..9625)
                     /locus_tag="RD488_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7657515.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="RD488_001433"
     CDS             complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="RD488_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HDT7657516.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQGIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="RD488_001434"
     CDS             complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="RD488_001434"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDT7657517.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13095..14555)
                     /locus_tag="RD488_001435"
     CDS             complement(13095..14555)
                     /locus_tag="RD488_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657518.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14545..15840)
                     /locus_tag="RD488_001436"
     CDS             complement(14545..15840)
                     /locus_tag="RD488_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7657519.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16172..16849)
                     /locus_tag="RD488_001437"
     CDS             complement(16172..16849)
                     /locus_tag="RD488_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HDT7657520.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16879..17970)
                     /locus_tag="RD488_001438"
     CDS             complement(16879..17970)
                     /locus_tag="RD488_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDT7657521.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18071..18505)
                     /locus_tag="RD488_001439"
     CDS             complement(18071..18505)
                     /locus_tag="RD488_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7657522.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19089..20546)
                     /locus_tag="RD488_001440"
     CDS             complement(19089..20546)
                     /locus_tag="RD488_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7657523.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20543..22438)
                     /locus_tag="RD488_001441"
     CDS             complement(20543..22438)
                     /locus_tag="RD488_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7657524.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22496..24271)
                     /locus_tag="RD488_001442"
     CDS             complement(22496..24271)
                     /locus_tag="RD488_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7657525.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24321..25817)
                     /locus_tag="RD488_001443"
     CDS             complement(24321..25817)
                     /locus_tag="RD488_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7657526.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(26011..27633)
                     /locus_tag="RD488_001444"
     CDS             complement(26011..27633)
                     /locus_tag="RD488_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7657527.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(28083..29396)
                     /locus_tag="RD488_001445"
     CDS             complement(28083..29396)
                     /locus_tag="RD488_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7657528.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(29641..29865)
                     /locus_tag="RD488_001446"
     CDS             complement(29641..29865)
                     /locus_tag="RD488_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657529.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(29885..30307)
                     /locus_tag="RD488_001447"
     CDS             complement(29885..30307)
                     /locus_tag="RD488_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDT7657530.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(30449..31159)
                     /locus_tag="RD488_001448"
     CDS             complement(30449..31159)
                     /locus_tag="RD488_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657531.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(31177..31673)
                     /locus_tag="RD488_001449"
                     /pseudo
     CDS             complement(31177..31673)
                     /locus_tag="RD488_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(31710..32162)
                     /locus_tag="RD488_001450"
     CDS             complement(31710..32162)
                     /locus_tag="RD488_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7657532.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(32297..32902)
                     /locus_tag="RD488_001451"
     CDS             complement(32297..32902)
                     /locus_tag="RD488_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7657533.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(33352..33972)
                     /locus_tag="RD488_001452"
     CDS             complement(33352..33972)
                     /locus_tag="RD488_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7657534.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(33974..34843)
                     /locus_tag="RD488_001453"
     CDS             complement(33974..34843)
                     /locus_tag="RD488_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HDT7657535.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(34866..35273)
                     /locus_tag="RD488_001454"
     CDS             complement(34866..35273)
                     /locus_tag="RD488_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7657536.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(35292..36581)
                     /locus_tag="RD488_001455"
     CDS             complement(35292..36581)
                     /locus_tag="RD488_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7657537.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(36608..>36821)
                     /locus_tag="RD488_001456"
     CDS             complement(36608..>36821)
                     /locus_tag="RD488_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7657538.1"
                     /translation="LGVEAKLDHCDISSAVSMKPDVIITAENFRSQFEKFAVDPKTAM
                     IYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT        10437 a         7899 c         6130 g        12355 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtattcaa
       61 aagatttatt tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg
      121 taatcaggaa actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct
      181 tttctgataa aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga
      241 aaaagaccca tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt
      301 gccaaatctt taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg
      361 caacttcttc tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta
      421 ggagtttacc atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa
      481 aaagaacaaa acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt
      541 ctttttattt tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc
      601 ctctagatat cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa
      661 atggatataa gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt
      721 ggcagttttc taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct
      781 cttctgtttg ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta
      841 gtattttcaa caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg
      901 gtcggatcga tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg
      961 tgattgctcc gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt
     1021 agtcatcgaa acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat
     1081 tctcgtcacc tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt
     1141 gtgccagggt ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta
     1201 ccttttcaac aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg
     1261 tgggttgcca agcataagct gagccatatc gtttttcata aattctttca aacaactgat
     1321 gctcatccac ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta
     1381 aaagtttcct tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga
     1441 ataattccaa ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt
     1501 ttgcttgttt caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa
     1561 gcctatcgat caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt
     1621 tagaaaggac tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa
     1681 acaaaggatc tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct
     1741 gctccgatac attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct
     1801 ctgctgaaag ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta
     1861 atgatggtag gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca
     1921 agtcatcgga tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga
     1981 tagcagaggt tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat
     2041 cccgaatgat tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg
     2101 tctcatcttg gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa
     2161 aaaacttgac caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat
     2221 cgattttatt ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt
     2281 cggcaattgg tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg
     2341 ctgtaccgat ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc
     2401 caaagtaggg acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct
     2461 gtttgatatt catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca
     2521 ggttatctaa gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact
     2581 ggtttccttc tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta
     2641 gcttttgata cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac
     2701 acattctcct ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa
     2761 tgcaagcttt ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt
     2821 tgatataaag aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt
     2881 ctttccgcta gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg
     2941 tctaattcat ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat
     3001 ttgccctttt ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt
     3061 tctgtcggca attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct
     3121 gcatatccta gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat
     3181 tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg
     3241 atccgtttat ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct
     3301 ggatggaaga tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct
     3361 tttcctgata catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt
     3421 aaaccggtgg atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct
     3481 tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct
     3541 ggtgaagcaa gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca
     3601 tcccccaccg cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc
     3661 ccgcgtatgc ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca
     3721 atggataaaa taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc
     3781 ccgtggtctt caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac
     3841 aattcttttt ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct
     3901 tgttcgatca ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg
     3961 atgaatcctg caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact
     4021 ttatcgatat ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga
     4081 atcgatggaa caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg
     4141 tgtttttgac cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact
     4201 tcatgatttg gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca
     4261 agaagatttt cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca
     4321 aaagaaacat acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga
     4381 agccgtgtag cagcagacat tccacctgct acacctccga caataacgat tttcatctta
     4441 tttccctcct actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc
     4501 ataaccagat ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat
     4561 cacatagacg gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt
     4621 tttagctcct tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc
     4681 tggattttcc aaaagctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa
     4741 tagcaaattc attttctgca cctcatttac atttttataa atacctcatg gggtatatta
     4801 aacaggagct ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta
     4861 tatttgcata aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt
     4921 tatggagatt gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg
     4981 tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag
     5041 cgctgttcgt tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa
     5101 ttgctttgag aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat
     5161 caagatgatt attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg
     5221 aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag
     5281 aaacgacgat tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca
     5341 atgcagaatt cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg
     5401 ctaatcatat ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc
     5461 ttgatttagt tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg
     5521 ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct
     5581 ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtact aagaacagcc
     5641 aaacaaaaat agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
     5701 tttgaacacc gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa
     5761 aaaaacggga aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     5821 tgattgaaca ccgtttacca agaggttgtg agcctaccat ttaactccga atcacaagaa
     5881 ataatttcaa aaacaacttc tcctgttttt ggtttggttg gcttattatc gagaagtagc
     5941 tactgggagt ctatttatca aaaaaaggaa tgcgacatag gtcacacccc ttttttattt
     6001 tctttgaaac atctttcggt actcgacagc atacaagaca aaagattgta aaagaccgta
     6061 agtgatgacg gcaaaaatga ctctcaccca cagcgttggt aattctggga aaagcagcaa
     6121 aaggatcatg ccaacataga tgacagcagt cgctactttg ccataccact tcgctccact
     6181 taatttgata tttttagata gcccgattaa tccagctaca aacataaagc cttcttttat
     6241 caagaataga ccaaacaaca gccaaagcca cggtcgatac catgccatag acaaaatcag
     6301 aaaaagttgt gtcaatttat ctgcaaacgg atcaagcacc ttccctaagt ctgttacctg
     6361 attatatctc cgagcaatga ccccgtctag ataatcagac aaacctgaga caacaatgac
     6421 cgctcctgct atataaaatg actgtctcag cacaaaataa agataaatcg gcagcaaaaa
     6481 aatacggaat atcgataaaa gattcggaat cgtttgtatt tctttacgcc agtctgtgct
     6541 taatttcatt ttatcgccct acctcctcag cactcttttc tttttatttt agcttacacg
     6601 gggaataaaa ccaatgattt cactgttttt atttttcttt acagccactg atattatgag
     6661 ctaatttgag ataatcactt gctgttttca tcgtttactc ttctttcttc ctgtcgtttg
     6721 cgcatttctt ttactagtac tttatgagct ttttttgatc ctcgctctag gtcacgctgc
     6781 cgtttacgtg ttttataatc gataaacaga ctgtctaaat cgtaacctgt cgggtacaga
     6841 tcttctgctg aacgcaccag acgaacacgc tgacgaggca cgtggattat ttttttgtct
     6901 aaatatacat caatcgtatc ttcacctata tcttcataaa ctaacgcttc tttttggtat
     6961 tcattgacaa atatccgatc accttttgca aagagctggc gttctttttt attctccttc
     7021 ctatttgtaa ctgctgtctt aggaagaaat tcttttttct gtgtccgata ggctttttcc
     7081 gccaagtaac gctctgcttg atggatcaat ttcatcgaca tatccatttt atgagcaatc
     7141 cacaaagctt ggctttctcc tgtttctcca acccgcaact gatatttagg acgaagtgct
     7201 tcccgatcga aagccatagc agccggcaca aaatcttcat gatctccggc gaatttcttg
     7261 atttctccat aatgggtcgt ggcaatgatc aatgcccctt gctcatacat agattccatg
     7321 attgcgatcg ctagtgcagc cccttcattt ggctctgttc cactgccaat ctcatctaaa
     7381 agtaccaacg tattcctttt tatctttttc aaaatagcag cgatgttttg catatgacca
     7441 gaaaatgtac tcaacgcatt ttctaaattt tggtggtcac cgacatcgac gaaaatctca
     7501 tcaaagacag caagctctgt cccttctttt gccggaactt gcataccgaa catcgccatc
     7561 aaagtcaata aaccgactgt cttcaacacg actgttttgc ctccggcatt tgctccggtg
     7621 ataatcaagc ctcgatagtc tttaccgatt tcaacatcca atggtaccgc atgctcaggt
     7681 aaaaatggat gtctgccttg cttgataatg atatgttccg atttattgat tctaggtgtg
     7741 cttccattga tttctcggct aaattttgcc cgagcaaaga tgatatctaa caccgtgatc
     7801 gtttcgatca ataaatcgat cacttcttcg ttttctgcga tagcaccagt caatgccgcc
     7861 aggacttgat attcttcact gatttcttca gcttttaaca actgatagtg ttcattcaat
     7921 ttagaaatca cagttggttc aataaaaacc gtcgttcttt tatttgattc atcgataatc
     7981 gttccatcta ttttattttt atagctggct ttgataggaa tcgtatagta ttcgcctttt
     8041 tgaacaatca ttgcttcttg gatcatttct ttgtttttcg gatgacgcaa gaatttcagt
     8101 aattttgact ggatttcttt ttcgattagt tgtaattgtt tgcgtacttt acgcaaatta
     8161 cgtgacgcgt cgtcactgac tttattattt tttattttct ggtcaatcaa ctcttctaca
     8221 tttatcaaat caggaagatg tttgctataa gcaaacaaca agggtgtctg gtattgattc
     8281 ttatcaaaaa actttgtgat catccgactg cttctaagaa aatccgcata ttcgatcaaa
     8341 tcggttggct gcagaatcaa cccttttttg acttgttctg tcagtgcatc gatcctcggc
     8401 aaccccataa atggaacatg ctgactgctt tctaagatca agcgtgcttc tcttgtttct
     8461 tcttgacgat ccaagacagt ttgtaggttt gtcgagaccg tcatatcgct gattcgtttt
     8521 ttgctatagt ttccaattgc tcttgcttgg atttcctttt tgatccgatc aaattgtaat
     8581 tgactaatca tttcgttgtc catattctct ccttttcttg aagagatacc tgtcccaaaa
     8641 taaataaggg cctagagata aataaaagga tagaacacag cttaaaaaag tcatgtccta
     8701 tccttattag aatacaaaga tattgttttc ctgacaggta ccgtttcata agcacaccaa
     8761 ataaactttg tttattggct attcgactta ctgattagat accagctaca ctcacaaaac
     8821 ataccccatt cttctaggtc ttatttattt tccacttaac tatagcaaga cacattttgg
     8881 ttgtcaaact ttagtatgtt ttatagattt acaccattaa tgaatagaca cctaccgcga
     8941 taattgctcc gatcattgga cctgcgattg gtacccatga atatgcccaa tctgaagttc
     9001 ctttattagc tattggcaat accgcatgtg ctaatcgagg accaaagtcc cgagcagggt
     9061 tgattgcata tcctgttggc cctcctaatg aaagaccgat ggctaagatc aatccaccta
     9121 cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc aacccaagaa
     9181 ctaatacaaa tgtaccaatt aattctgtga tcacatttgc tggataattc cgtatagcag
     9241 gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc caatgtggca
     9301 aataagaaag ccaaacaaga atggcccctg caaaagctcc taaaacttgc gcaatgatga
     9361 aaggaacgac aagattccaa ctaattgccc ctgtcatcgc catagctaga gagactgcag
     9421 gattcaaatg agctgggccc atgaatccag aaatatagac agccattgtt acagcgagtc
     9481 cccaaccaaa tgcgatgaca atccagccag aagcctgtgc tttacttttg tttaaattca
     9541 cagccgcaca cacaccatct ccaagcaaaa ctaggatcag tgtcccaata aactccccca
     9601 tgatttgagt catatcactg ttcatttatt tctccccctt tagttcccgc agatctgatt
     9661 ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct gtccattcaa
     9721 aatatccagc aattgcatcg atcacaggtt gcttgatctc atcaagctga tctcgttcaa
     9781 acaacagatg atttgtacga cgaatgagat aatcgcctgg ggccaaaacc atttcttctt
     9841 ctaaaccata acgtaaccga gctgactcag cgagactcaa accaggataa ggtgccattt
     9901 cttttgctaa ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg atataagtag
     9961 catcttcttc ctctaaaccg gctgctactc cttcttttgc taattctgtc actgtttctt
    10021 ctaatttagt tggatcgaag tttccacctg aaatctgata ttttttagag tcgatttctt
    10081 tcgtctctat tccgtattct tcttttaata attggcgtat caatcgcaaa gctccttctg
    10141 ccatcttacg gtaatcggtg attttcccac cagataaagt cagcaaacca tctggttctc
    10201 tttctaaaga actacctctg gaaatcgtag aaggtgcttt ttcatcacgg ctgttttcca
    10261 aatggttcaa cacgtcttct acttcagcac gagaaacttt gttttcctta tattcactta
    10321 ctgtatcgac aactttattg aagctcttgt ctgaaatcga tccattatct ccaccattgt
    10381 aatcagaacc agaattacca atcaacagtg gacgaagtcc tgcccagctt gcttcgatat
    10441 cattcaatgt gatatttgct tctggatagc gatgattgat cacatccaat agataatcta
    10501 catcttcttg tgtgactttc ggatccgtaa aatctccttg gtaatccgta tctgtcgtac
    10561 caaagtaagt cttgttttct cttggaatag caaaaaccat ccgcccatct tgctttcctg
    10621 tatcgaagta tgtgggttgc ggtacaggca gttttttcgc atctacaact aaatggatcc
    10681 ctttagttgg acgcatttta ggagagactg gacgcgtaaa attcaagttt cgtactttat
    10741 ctacccaagg accactcgta ttgatcacta attttgcttt gatttcgatc acttcatctg
    10801 tcagcaggtc acgagctttg acgccaacga tttgatcgcc atcatataaa aagccaaccg
    10861 ctttcatttt acttactaga taagccccat cttcggcagc ctttttgata ttatcaatca
    10921 ctaaacgggc atcattgttg cggaaatcta gatagacacc cgcgcctttt agcccttctt
    10981 ttttcaaaaa cggttctctt tccaatactt cttctggtgt cagcgtataa ttctcatatt
    11041 tggttcctgt cacatttgcc agtttgtcat aaaggtccat tgctactttg accgagaaca
    11101 tattgaaggt tgttgctcct tcgccctcat agattggcaa aagcattgga tctggttttg
    11161 ggatgtgtgg ggcaatacct tgtacgactg cacgttcacc aactgtgtca gctactactt
    11221 ccacatcaaa tgtcttcaga taacgaatac cgccatgaac aagtttggtc gagcgagagg
    11281 aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct gatgctgctg
    11341 actggactgc cacaccggca ccagtgattc cgccaccgat gatcaacaga tccaattctt
    11401 cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata tggatttcct
    11461 ccttattcaa atgcttgggt agcttttact gcttttttcc aaccgttgta aagtttttct
    11521 cggcgctctt cctccatttg aacttcaaat agcttgccag cttcataaaa ttcgcggatc
    11581 tcgtctgtat ctttccaata accgacagct aatcctgcta aaaatgctgc ccctagcgcc
    11641 gttgtttcca agttttctgc tcgttggatc ggtacattca agatatctgt ttggaattgc
    11701 atcagatatt cattgtttgc tgcaccgcca tctactttca atacaggaat cttgattcca
    11761 gtgtcatctt gcatcgtatc gatgatatct ctcacttgat aagcaatcga ctgtaaagta
    11821 gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc ccctcgtgct
    11881 gcctgatccc aataaggagc acctagccca acgaatgcag gaacaacata aacctcatct
    11941 tcgcttgtag agcgtttcgc tgcgtcttct gaatcgctag ctttttgcaa catttgaagt
    12001 ccatctctca gccattgaat cgaagaacca gccacaaaaa tacttccttc taaagcatag
    12061 taaacctttc catttatgcc gtaaccaatt gtcgtcaata aattattttt ggataattgc
    12121 ggtttttcac cggtattcat gacaataaat gaacctgtac cataagtatt cttgaccatg
    12181 cctggttcga atgccatttg tccgaataat gcggcttgct ggtctcctgc catccctgaa
    12241 attggtgctt cgcttccata aaaatgataa ccttgcgtat aaccataaac ttctgagtta
    12301 gaagtgactt ttggtaacat cactcgagga atatttagta aatctaaaat ctcctgatcc
    12361 caatctagct gatggatatt gaacaacatc gtccgactgg cattcgagta atcagtaaca
    12421 tgtgcttgtc catcggtcag tttccatact aaccaagaat cgatcgttcc aaacatcaat
    12481 tcgccttttt cagctcgttc ttgcgcgcct tctacatgat caagaatcca gcgtatcttc
    12541 gttgctgaga aataggcatc gatcactaac cctgtttttt cgtggaaaaa ttcttgatag
    12601 ccttcatttt ttaagttatc tgcaattcca gctgactgtc tggattgcca aacaactgca
    12661 tgatagattg gacgtcctgt atctttttcc catattactg ttgtttcacg ctggttcgtt
    12721 atgccaatcc cagcaatctg atttggtttg atccctgatt cgatgaacgc tccggcaata
    12781 actgactgta cagaattcca gatttcattt gcatcatgtt ccacccaact ttcttgcggg
    12841 aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt gtcaaagata
    12901 attgctcgtg agctagttgt accttggtca atcgccatga tatacgttga ttctgtcatt
    12961 gtgattccct ccattatatg caaacgcttt ctttaactac tcttatcata ctactgtttt
    13021 aaaaaaagaa actgtcaaaa ttttattctt tttttctttt tttgacagtt ttttattatg
    13081 aagctatttt ttaatcaatt cttttctttt ttcagcgtct ctattcttct tttcaatcga
    13141 ataatgtcgt aaggtgacgc aaattctgac agataatatt cacactgttt tttgtttctc
    13201 tggcaaaatg tgatcaccaa atcatattct ttaccttctt cataacttcc aatctcaata
    13261 ccgccgattc ccctcagttc tctgatcaga tattgttgaa aagcaatacg ataaatcggc
    13321 agactttcta aatcgattcc aatcactact ggttttgcaa tataaaaatc gatcatcaaa
    13381 agaacattgg catactggat catcaggtaa ctaagctcac tatcttcagc tcttttcctc
    13441 ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa ggaatgcccg
    13501 agcattttct gctgctgttc caaaagccga tcacgctcat agacttcgat ctttccaaca
    13561 aagaaaaacc attcattgtt gatctgggaa atttggtagc ctactgcctt ttcttctttg
    13621 attttcaaac gacgaggacg ataatgccat aacatcgttt cccgaatgta agtatctaaa
    13681 acagcggttg gtaacttttt gctccgtgtc aaatcatact gataaaatat ttcttcgtct
    13741 actatcgaaa aagaaacaaa aaagctgtaa aacatcattg tttcgtatac attcagttct
    13801 gctgctgttc gactaagatg catcacgatg attggatcga ttgcttgata aagccggtcc
    13861 gactgataga gtaatttctt ttctttcaaa gttgcgtacg tacttttttc attcaatagt
    13921 ctttttttcg taatcccgag ccagcaagca atctgtgctt ctgctgatgc cgtaaacgtt
    13981 gtttctaata cacggtccaa tcctagaatg aacggtcttt tttctggtgt attttgcaaa
    14041 aaaagcggtc gctgatcttc cgggatatat tggaatagtt cataataaaa atatcgtatc
    14101 tgtagctctt ctccgtataa ttgaccgttt ttgatttgta atccaaattc ctctaagagc
    14161 tggttcaatt ctttgatctt tcgaaaaaca gaagactcac tgatattaaa cgctgtcgct
    14221 aatcgaacga tggatacttg ctgatgttct aataaataga cgagcatctt aaacttcaag
    14281 ctttcctgca ataaaaacaa tagaattttt tccaaactta catcttcgtc caacacaagc
    14341 agcgcctgat actcatttcg ctgtacttct actttttttt ccatcattcg gccaatcaat
    14401 tcaatatctt ccaaatattg atcaaacgag gcttttgaca gttggacatg ctctctcaaa
    14461 ccattgatag aggctgttcc cccttgcaga acaaggtttc gcaaaatcag gatctgtaac
    14521 tgctcttttc tttctaataa tgcttcaatc ttcataggca gtattcgcca cctttgacca
    14581 caccatatct ggcacacggt attctggctg gaaaaatagc tcatgttctt ctaactgttc
    14641 aaacgtccat ccttctttta ctgcaattgt cagttggtca agaaggtgga acatctcttt
    14701 tttgctttgg agctgtgctc caagaatctt tttttcagaa tcaaatagaa atttgagttt
    14761 aactttgctt tgatttattg ctgtaagctt gtagtctacg tatcctgttt caattttttg
    14821 gggataaaaa atgctctctt cttctgtcaa acctacgctt cctaagaaat agccaaacca
    14881 ctgattgccg actggacgat aggttccctg atcctttgtc tgtgagccac taattgtctt
    14941 gctgacattt cgtgctgtac ggacagcgtt atttactaga gaaacataca ttttttcatt
    15001 tgttggacga aaagttactt ggatcgcatc gccaatcgca taaacgtctt tttgagacgt
    15061 ttgcaagtag tcatctaccc agatcgttcc atcatcattc aatgttaatt gttcttccca
    15121 catctgattg tcggggcgag aatgattagc cagcaaaaca agatcatagt tctcctttct
    15181 tttttccgtc tctacaatag cggtttcatt ttcggtcaaa gacacaactt gttcttctaa
    15241 aaaaagtgaa agcccttgat ttttcatttc ctttactaac ggttctgtca tttcaggatc
    15301 tagataacga aaaagaattg actttcggct ttcgtaaaga tggatttgtt tttttcttga
    15361 tgccaaccct tcagctattt cgattcctgc ttgtcctgca ccaataattg caattttctt
    15421 tgcattcatg atcttttgct gaagagccgt tacgttttgt atctttttaa ctgggtgaat
    15481 aagcgttgat tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg ctagaatcaa
    15541 acgatcaaaa tccaattttt ttcctcctgc taaaacgact tttttttctt tcaatcctat
    15601 tactgtcttt tctgtgtaaa catggattcg atagcggtca gtcagttctt ctttcgtgat
    15661 ccaagaaagt tgtttttcac tggtaacctt tccttttaat atcaaattga acccgctggg
    15721 aatccatcct aacttcgatt gcttttcaat caaatatatt tcacttgttg gcatcaattg
    15781 gcgaagataa atagccgcat gaatccctgc aaacgacccg ccgacaatta caatgttcat
    15841 ctgcattcct ctttcttata aggtgttcta ctgctaactt ctcaatcaga aaacacagta
    15901 ttcataactc gctttcaacc ttatgataca tagcgatgca gcagaatcaa ccctctccat
    15961 cataccgtgt tctaggtctg cttctcaata atgtactagt ggacctaatt gaagagtatc
    16021 atttctgaag agatgtttca aaaaatgtac tcttataaaa gaaaaaaact cgccttttac
    16081 gtacctctgt ccaaatagga aacagaaaag aacgaaaaga cgagttttag cgtgtgtaat
    16141 gtaatagtta gaatagacac atcatttatt tttaattctt taatgcttca acaactgctt
    16201 cgcctaattg atgagcagat tgaggatttt gccctgtaag aagccgccca tcaatttgaa
    16261 ccacttctga aaaagctgct ccagactgat agtttgctcc tttttctttc aaagcatctt
    16321 ctgctaagaa tggtacttca ttcgttgtac catttgcttc ctcttcttca ttactgaacc
    16381 cagtcactgt acgtccagct aaaatagatt ttccagactc atctgtaact ggcaacaatc
    16441 ctacaacacc gtgacaaaca gctgagacca gcccttcatt tcgatagatt tgtgaagcga
    16501 ctttcccaag atctattgct tctggaaaat cccacattgt tccgtggcca ccagcataat
    16561 aaaccgctgc ataatcattt gcatccacat catcaggacg taaggtattt cccaaggccc
    16621 gatttctgaa atcttcatct tcataatagg cccaatcgat ttcatccata ttcaaaacac
    16681 tttgcggttc taaaggtaca tatccgcctt taggactgac aaaatctgca tcgatcccat
    16741 tttttactaa tacatcataa aaatgagtca gttcacttaa ccacaaacct gtaggacgct
    16801 cgatcttttc gtacttttct acatttgtta atacgatcaa tactttcatt ttcccatcct
    16861 ctttctataa aaattgcgtt attgataacg tgctttcaag aaattatata atgggcttgg
    16921 caaataaagc tctttatatg cttcttcaaa aggtttcgtt acaaattcat cctcacggtt
    16981 ttccaataat ttctctgccc agtcaggatc gacgatcatt tgctgtccaa ttgctgcaag
    17041 ttctgcatat ttcaatacct gctctacatc ttcgcgattg cggatcccac cgacaccaac
    17101 taaagggatc tttccttgaa tcgtgttatg gaccacttca agaatcgatt tatcgttgta
    17161 tttatcagaa cgagctattc gatcatacat atttaatgaa acatgcagat aatctagttt
    17221 tgactcacgt aatcgttcaa gaagccagat cgtgtcttca aaacggatac ctggtgtttc
    17281 atattcttct ggtgagaaac gataccctac gatgaatggt tttttagcat attgttcaac
    17341 cgctgagaaa accgttgtta ataattcttc aataaaacga taacgatttt ccaagctacc
    17401 gccccattga tcctctcgtc tattcgaatg cggagagaaa aattgttgga tcaaatacgt
    17461 atttgctcca tgcaactcga ttccatcaaa tcctgattca atcgctctac gtgtggcttt
    17521 gccaaatgct tggattgttt caacgatttc ttcttcactc attgctcgtg gtgtttccgc
    17581 atcaggacgt tttgctgcaa ctgcacttgc agatacaggc tgttctccag ataaagttgc
    17641 tcgacttgtc attcgtccac cgtggaaaat ctgaataatc gcttttgcgc cttctccttg
    17701 gattgctttc gctagctcac ttaatcgagg aatcatttca tcatgagcga tgctgagttc
    17761 acctggccag ccttttccga tatcttggac atttgcagca ccagtaataa cagcaccaag
    17821 acctttagaa cgttgtttat aataagtgat ctcatcttcg gtgatcactc cattgaaaaa
    17881 gctgagttgt gtcgtcatag gcgacagcat caatcggttc ttcaattgaa ctcctgaagg
    17941 taaagtaatt gattgatcaa attgtgacat tgtcattcct cccataattc gctctgatta
    18001 acctatcgag aatcatctat cattaaacca ctcgattagt tgtacatgca actaatttgc
    18061 ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc attcattgtc tgggctaatt
    18121 ctttacttgc ttcatttccc aaaactgctt tgtatgactg atgaagttct tcccagctac
    18181 catcgacttc cttagcaaat tggcgtcctt gttctgtaag ataaactaat gacaagcgac
    18241 cttcgctaac tgttttgacg tatcctttat attctaattt ttcaacaaaa cgagcaatcg
    18301 ttgatggggc ggaatagagc atttgtgcaa tatctttttg tggtattcca tctttttctt
    18361 ttaatatcaa taaaataaaa ccataagttg gtgccagacc tgtccttcta aacgcttcat
    18421 cagctaattt attcaacatg cgatctagct ttttcacgct aaagaaaaga cattcatcta
    18481 acgctttttc aattggcttt tccatttcat cccctccatt ggcgtacata tcatagtatg
    18541 atttttattt tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct agatttgaaa
    18601 aaaagaagta gccatcttca aagaatttcg gcttgttttc gacaaaactc cttctggaac
    18661 accgtgaatc agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa aaattttgtg
    18721 aaaatggctt tccacatttt tgcataaatt tggcttaata ccgaaaaact ggcttttgaa
    18781 caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa gaacagccaa
    18841 acaaaaatag ttcctcatat tttgtcgttt tttgagctaa tgccgatggt cagctgattg
    18901 tacaccgttt attgagaggt cgtgagcctg ccgttgaact ccgagtcaca aggagcaatt
    18961 tcaaaaaaca gcttctcatg ttttatgact atggtgactt gtgatcgagg agttggcagg
    19021 agaatactgt ttattcgtaa agaaggggct gtgacaagac ttttgtcaca gtcccttatt
    19081 tccttttatt ataggatttc gccatttgat tggatgactt gtctgtacca atcaaatgat
    19141 tttttcttta accgtttctt tgtgccattc ccttcgtcat cttgatcaac atagatatat
    19201 ccataacgtt ttgacatttg tgaagtagaa gcgctgacga tatcaatgca gccccacgac
    19261 gtataaccaa ataaatctac tccatcttcg atagcttcct tcatctgctc aatatgctgc
    19321 ttcaaatagt caatgcggta atcgtcttga acggttccat cttcttctac tttgtctata
    19381 gctccgagtc cgttttcagc tatgaacagt ggtttttgat acctatcata taattgattc
    19441 aaagcaattc tcaaaccctt aggatcaatc tgccagcccc attcacttga tggaagatac
    19501 ggatttttaa ttcctccagt tattaagttt ccttggaccc cttccaaatt ttctggatga
    19561 gcactgactg cactagacat gtagtagcta aaagaaacaa aatcaacagg gtaggctgct
    19621 aagatttctt catcacctac ttctattttt aagttgacac ctttttcttc aaacattcgt
    19681 tgcgtatacg ctggataata tcctcttgct tgaacatcac taaagaacaa agaagttctt
    19741 tgctgctcaa ttgttttttg aatatcatcc ggatcacaag aatacggaac aagaagctga
    19801 tagctgatca tacaaccgac ttgtgaacct ttgataattt catgacaagc ttttgtagct
    19861 aaagcacttg ctataaactg atggtgtgca ccttggtatt tcgcttgttc caaatgggga
    19921 tggttttctt caattactcc tacgctaaca aaagggtgat gttttacaca gttgatctca
    19981 ttgaaagtca tccaatattt tactttattt ttatagcgtt tgaatactgt ttcagcgaaa
    20041 cgaacgtaaa actgaataag ctttcgatta ggccatccac catattctgt aaccaaatat
    20101 aacggcattt cataatggga aagagaaacg actggctcaa tcccatattt tagacattcg
    20161 tcaaacactt gatcataaaa aaataatccc gcttcattgg gtgtttcttc atcaccatga
    20221 ggaaaaattc ttgtccatgc gatagacatc cgatagcatt taaaacccat ttcagcaaat
    20281 aaacggatgt cttctttaaa gtgatgatag aaatcatttc cgtgtctttt aggataataa
    20341 tacttgctgt tgggatcctg cgccgctttt acttgctgat gcgtcatcat atgccattga
    20401 tctgtccatt tttctttagg taaatcgctg tcgaatgtat acacatcaga cacagataat
    20461 cctttttcat ctacatccca tgcaccttca cattgattgg ccgctgtcgc tccgccccat
    20521 aaaaatcctt ctggaaattt tttcatatcg atccccctaa acttgctagt tttcttgttt
    20581 gattattttt cttatgacta gtaatgatat ttttgaatct actactattt gtaacaataa
    20641 ccattgtggt cggatcatat ccctctttga ttaattcttg caaatctact tccatcaata
    20701 aatcgccttt acgtactttt tttccatcag atactgcact ttgaaagtat ttgccattta
    20761 aattcactgt atcaataccg atatggatca gtatctctgc tccttcttca ctgactaccc
    20821 caattgcatg tttcgttgga aaaactgttg aaacttcccc gtttacagga ctgtagattt
    20881 ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga tccactagca aatgttggat
    20941 cgtttacttc agataaatca attatttcac ctgctgcagg agtacttaac actatatcct
    21001 ttgaggattc ttcttcgatt tcatccttgt agccgaaaag aaaagttagc atacaggaac
    21061 tgatcatcgc taagaaataa ctagcaacta gccaaacaaa tccttcacca atataaatcg
    21121 ggaaagacaa aatacttctt gtagcaactg ccaaagcacc ggctcctgcg gcaccagcta
    21181 ctccaccaaa tatagctcca catatacaag caatgtaaaa tggtcgttta tatttaagag
    21241 tcacaccata aacagcaggt tcagtgattc caaataatgc tgtgataaat gcagataaag
    21301 ataaactttt tactttctta tttttcgttt tcaaaaatac cccaagtact gctcctgctt
    21361 gcgcagctac ggcagtcata catgctggac ctagcgtatc acgaccgtag aaagaaagat
    21421 tgttggtcat tactggtaca agtccccaat gtaacccaaa aatcactaac acttgccaaa
    21481 atccgccgat aacagcacca gataaaacag ggctaaagtt ataaacagct aaatatccag
    21541 ctgcaatcag ctgacttgca taatctgcaa ttggacctac aactaataaa gtaattggga
    21601 ccatcacgat gatacaaatg aatggtgtca ataaatttcg aatactttcg tgcaagcttt
    21661 tgcgaatctt aggctcaata taagaaagaa cccatacagc taaaattgct ggaataaccg
    21721 tacttgtata tcttgctaga atcacgggca tccctagaaa tcgcaaggtt atgctatcac
    21781 tatatgcact gacaatcgta ggataaacga gagctgctgc aataaccata gcgatgaaac
    21841 gatctgtatt gaactttttt gcagcagtat atgccaaaaa tataggcaag aaatagaaaa
    21901 atgcatcagc tgctgcattc aaaatgatat aagttcctga ttcagtagtt aataaattca
    21961 aactcgtaca taaggcgagt actcctttga tcaaaccact tcctgccaag acgcctaaag
    22021 tcggggcaaa aacagcggcg atcatgtcta taaaagagtt taaaatgcct tttttctcag
    22081 ttcctctctt tccactagat gcatcatctt ctagtttcat ttgtttggat aatacgtcat
    22141 acacttcatt tactgcattt cctactacga cttgaaacat tcctccagct tcgactacag
    22201 tgatcacacc ttctagttgc tctaccttct ccttatctgc cttcttatta tcttttaggg
    22261 taaagcgtaa ccttgttgca caatggtaaa cattgctgac attttcttcg cctccgacaa
    22321 atcggacaat atctttcgct aattgtgaat agtccatttt tacttccccc ttgttaatta
    22381 atgccgtagc aatccttctt acaagataag tatagttctt agaaaacggt ttctccattc
    22441 aattagtacc ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg tttacttagc
    22501 cgagcaaatc actcactgct tgaaagaaaa caagtatatc gtttctctta tagtcaaagg
    22561 agacaaaaaa aacacgcttg atcttccttt gctgatgtat aagtggtatc tcaagctgat
    22621 actctgtgat ttttgtttct acttggcttt tgataagaca gcacaacaaa gtctcggcat
    22681 ttaacggaag cataactagg tcagaactag gagagattag ttgctgaatg gaatctatct
    22741 ttttatggat ttttatttga ttttcttctt tgtagtaatg atcaagcagt tttgttttct
    22801 ttttttcttc aactatggtc agcttttcac gcaaaatctg ataaatctcc gaagattcaa
    22861 actcatctag aacactaggt agataaatca aatcatccca ctcaaaaata agctcttgct
    22921 cagtagtcaa aattgcatca tattccgtta ttttgtttga ttgatttttg aaaagataca
    22981 ctggttctat ccggcattct ttgatccaca tgttcatact ttgttgaatc tgttttttta
    23041 gtgtattcaa aatactaatt ggctggttac taacaatcag tatctcccct tgttttcgaa
    23101 aaggattcaa cgcttcggca agatacaaaa ccaaataagc gctttcagct aaattgggac
    23161 gtaattgaaa atgtattggg aagaaacgcc gaattaaata aatttctaaa ggataacggg
    23221 agatgatctt ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc ctcgttttca
    23281 tttgtttgat atgggttagc aaaaattctg tttcatggaa caataacgaa acaggaagat
    23341 ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt cttctctatt tctttgtttt
    23401 tttcatcatt aatcatcaaa taatttaact ctaatagtcg attttcaatt gcttgttttt
    23461 cttgattgga aaaagaatag ggtagttctg atgataactt ttttgtgagg gtctctacca
    23521 tcggaataaa taatgtatac ctgtttgttt tttctaaaag ttcttctctt cgaagaatgg
    23581 tcaaaacgag ataccgagaa aatcgtatga agtcctctcc tgaaacaata taattatatg
    23641 atataagaac ctcttttaat gtcttttgga cagtcggcat gatattggaa aaaattgtac
    23701 tgatttgttg aggcaacctt gcgtgttgga tcaccgtttc tgttccaaca agagataaga
    23761 aaattctttt tgaattttct tcagcaatga tttttagtcc ttttgtcgac gaaacttcca
    23821 gttctaattt aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt aatgatacgg
    23881 ctgtttttga aagaaagaaa atgtctgcta tcttttgcat actgacatac cctttttgaa
    23941 acaataagta cgtcacaata gttgaagctc ggaaatccat gctggaatag attttatgtt
    24001 tcgtcacctc ttgtatgatt tgctgtttag tttcagattc aattgattct aaaaaataac
    24061 ctgaacgttt atttgactgg ataatgattt tcttctcgta gatagcaagc atatttttga
    24121 tttcagtttg gatcgttttc ttgttggtac ctaaagcttc agctaattct tcgcttgtta
    24181 tccaatgatt cttatttctt aatactacaa gaatttggag ttgtcgttta tttaagtcca
    24241 tttgcttaca cctcctcttt gttataaaca tacaggaaaa acctctcaaa tgacaatagt
    24301 cacttgcaga ggtttaaaaa tcatttgaag aaagatctat attcaaggtt tttaccatta
    24361 gactggataa tttgtttata atattcaaaa ctatcttttt tcaatctcct aaagcttccg
    24421 ctcccatcat tttgtctatc cacataaata aagccatatc gcttcctcat ttcccctgtt
    24481 cctgccgata cgatatcgat tggtccccac cataagtaac caatgatttg gcaaccatct
    24541 tttattgcct cagcaatttc ctgaagatgt atttttagat actcacaacg ttttggatcg
    24601 tggattcgat tcaattcatc tggtgcttca tctagtccaa tgccattttc aactatgaat
    24661 aatggtaatt cataacggtc tgtcaattca ttcatgacat aacgaaaccc tagaggatca
    24721 attggccaac tccaaggttc gggagatttt tccttcaaaa agggattatc gaaaccattt
    24781 gctccgccag tatctacgcg catttctgct tcttttttat agacagcgct acgataataa
    24841 ctaaatgcaa tataatctac cgtgttagct tgcaagtact gttcgtctcc atctaacatt
    24901 actggtgcac agtcttcttc cttccatatc ctgtaaatat aagctggata atgccctcgg
    24961 cacatgacat cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc aaatacattc
    25021 tctggatcac agtcatatgc ataagtcgct aatgcagaaa agctacacat aatacccatc
    25081 ttagcatttg gatcgatttt ctttaataat tgagtagcac gggcgttcgc tagaaacata
    25141 tgatgacagg cttgataaat ctcttttttt gttagtgtag caatgggttc aagtttatct
    25201 ctagcaggga atgtaaccaa tccagcagct gcataaggca tacgaaaagc attattgatc
    25261 tcattaaagg tcatccaata tttcactttc ccttggtagc gttcaaagac ggtctgcgca
    25321 taaaattcaa aaaagtcgat taattttcga ttttgccacc ccccatactc tcctaccaat
    25381 gctaaggggg tttcataatg actaagagta attactggct cgatatcata tcgatttaat
    25441 gtattgatta gtctgtcata aaatacgaga ccagcctcat ttggcttctg ttcgtctcct
    25501 cttggaaata ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc taactccttc
    25561 agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg agaaagataa
    25621 tggagtgatt cgtctaaagc aatctcccaa atcttttttt cttcattcca ctgaatacta
    25681 ggatgctggt tcatgatccc gataagcgta tctgtcacat taggtaattt gccgtcttcc
    25741 aaccatgcac cttcacattg attagcagct actgctccgc cccataaaaa attttctgga
    25801 aatatttcct gatccataac tatctctcct cgctatcaac aatttcttac ttgaagtata
    25861 gctcgattca tcaaaacaag atattctaac tatttcggca gaagagaaga aaaaaattga
    25921 atgctactct tcatttttaa tatttatata taacaaatac ataagacgat ccccgaaaga
    25981 aaacactcgt taaccatcta agcaaacgat ttattttact tccaacacaa atgcttcata
    26041 aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga ggataatttg acacaataac
    26101 ccttaaagct tcacgtggaa cagtgaacgt ctgcttttca ctggacatat tacaaataac
    26161 gagccattgc tggtcttcat atatgcgaga ataggcaaag acatgctcag gcgtcttttc
    26221 cactaattca tagtctcccc agacgatgat gtcatgtttt ctacgcaaat cgatcaattt
    26281 cttgtacata taaaaaacag aatcttgatc tgctaacgct tcttctgcat tgatttcttt
    26341 ataatttgga ttgactcgaa gccatggaat tccagtagta aacccagcat gttcacgggc
    26401 gttccattgc ataggcgtcc tagcattgtc tcttcctttc gcattgattg attccaagat
    26461 ttcctctttt gtaaatccag aagaaatcct ttcgttatac atattgattg tctcaatatc
    26521 ttttgcttcc gcgatatcat cgattgggca attcgtcatg cctaactctt ctccttgata
    26581 gatataaggg gtgcctttca tcatatggag caagatagca aacatcttgg cactttcttt
    26641 tcgatacaca tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt gattattcca
    26701 aaataaacta ttccatcctt catcacctaa agatgtttgc catttggata atactttttt
    26761 cagttcagag atactcaagg gtttcaaatc ccatttgtct ttgccttctt gctgatctaa
    26821 tcctatgtgt tcgaattgga agaccatgga taattcattt cttttaggat tggaataaag
    26881 tttagcgatt tcggtagttg ctccccatgt ttcgccaaca gtcatcagat ttttgtcacc
    26941 aaaagttgct tgattcattt cctgaagata ctcatgcagt ttaggtccat tacttgtgat
    27001 ttctttatcc ggttctttgc caatcatatc gatcacgtcc atacgaaagc caccaatacc
    27061 tttatcgatc cagaaattca tcatttgata aatctcttgg cgaacctgtt tatttttcca
    27121 attcaaatca ggttgacgct tgctatacaa gtgcagaaaa tattgccccg ttttttcatc
    27181 caactgccaa gcagaaccac tgaatattga gcgcaatcta ttaggctctt ttccattgac
    27241 cggatcacgc caaatataat agtcccgata aggattttct ttatttttac gggcctcaat
    27301 gaaccacgga tgttcatcag aagtatgatt caccaccaga tccatgatga tacggatatt
    27361 tcttttcttt gcttcttcaa tcagttcttc catttcttcc atcgtaccga attctgccat
    27421 gattgcttga taattactga tatcataccc attgtcatca ttcggagact cgtatactgg
    27481 agaaagccaa attgcatcaa tacctaaata cgccagataa tccaacctgg aaataatccc
    27541 ccgcaaatct ccaataccat cttgatttga atcttgaaaa cttcttggat agatttgata
    27601 aacaactgaa tggtgccacc atttttgttc catgattttc ctcctataaa tggatgtttc
    27661 tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac gctttcaaat
    27721 agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga ggaaattccc
    27781 tcaactgttt tttgaaagga ttgatttatt cagggaagaa tgctgatttc acaacttctt
    27841 tataaacggt gttcactcag ctgtccctcg gtattagctc aaaaaacggc aaaatataag
    27901 aaactatttt tttcgttttt ttctctaata ctcaggccag aacactgatt tcacaacctc
    27961 tttataaacg gtgttcactc agctgtccct tggtattagc tcaaaaaaag gcaaaatatg
    28021 aggaactatt ttttcgtttt tttctctaat actcaggcca gaacactgat ttcacaacct
    28081 ctttatttca cattcaatat ccacatgaat cccatgaata caaagaacag accatacatg
    28141 atgggagata cttcttttcc tcttttagct gctaacatgg taattggata gaagataaaa
    28201 cctaatgcaa tcccatctga aatactataa gtcaaaggca tgccgatcaa gatcaagaat
    28261 gaagggatcg caatctctaa gtttccccat tcgatttgtc gcaaagattg tgccatcaat
    28321 actcctacca taatcaatgc tggtgcagtt acttgtgaag taacaactga tagtaatgga
    28381 gaaaagaaca agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt
    28441 cctccaacgg cgataccagc tgatgattct acaaatgcac caacaggaga agtacctaat
    28501 aaggaacccg caagcatagc tgttgaatca gaagctaaag ctttccctac acgaggcatc
    28561 ttgttgtctt tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc tgctgtatca
    28621 aagaaagtca caagcaagaa tgtcagcact acgacccaca tttgaagaga attgatgtcc
    28681 cctacatgtt ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt
    28741 tcagaaggca ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc tgccatcccg
    28801 atgaagatgc cacctggtac acgccgaaca agcaagatag cagttacgac taatccaaaa
    28861 atcgtcaacc aagtagaacc aacgttgagt gatcctaatc ctactaatgt agattcattc
    28921 gaaacgatga tcccaccttc gctcagacca aggaaagcaa taaatagacc gataccgcca
    28981 gaaatcgcat atttcaaatc tgctgggatc gcatcaatga tcatttcccg cagcttgaag
    29041 attgtgatca aaataaaaat caaagaagca acgaatacgc cggctaatgc tgtttcccat
    29101 ggaatcccca ttcctaaaca aacagaataa gcaaaaaaag cattgatccc aagagcaggt
    29161 gccgttccaa ttggataacg ggctaatacc cccattaaaa tacagccgat cgcactggct
    29221 aatgcagtcg cagtaaacac tgctccttca tccattccag aagcacctaa tacagttgga
    29281 tttacaaata agatataagc cattgagata aatgttgtaa atcctgccag tacctcacgt
    29341 tttaccgtgg tgttcaattt ttctatttcg aagtaggaaa gtattttttc cttcatcttc
    29401 catcccccta aatccgaaca ttataaataa agtccgttaa aatttcgatt tattaataaa
    29461 acaacgtgtt ttatcatata ctaaaacaaa acataagtaa acaaaaaatt cggattttaa
    29521 gcaaaatccg aacgttccat ctgattaaat ccctttatct caaagttcat gaacattcac
    29581 tttggattac aagaatttct ttattgtgtt aataaagttt cttcattcta gtctcaaaaa
    29641 tcaatagtgt gatttgattt taccatttcg tttctgttct tctttgatga attcttttgt
    29701 atcgacagga ttcagattat ttagtccgcc aaaacctgta tcgaccattt ttccccagcc
    29761 ttttgtcttc ttttttcctg atttgagatt ctttgctcga agcttctcac tatgttttgc
    29821 tcgccgatac ttcaaataac cttctaatct tcccattaga tccactgttt ctcctccttt
    29881 ttattcaatc agacgactca gcttttccta taacaaaata attgccttca gggtccgaaa
    29941 aattgaaagt caagacgcca ttgttgtctg tgatttctcc tggttcttcc atgttctcgt
    30001 agatagtttc aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct aatacctctg
    30061 gtgaaaactt ctgcacaaat acttttggga atacgcctaa ttctaattct tttgagatgc
    30121 tgagtacaat actcttaaat tcttctggca attcgattgt ttcagaaatt tctgcaccaa
    30181 ttttttctac aaagaatcgg caaatcatct ctacgtcatt gacataaagc atcacacgtg
    30241 ttttttgtat catcgtttga cccttctttc tatttgattt tctttcctgt ctataaactg
    30301 attccattat atcacgaaag cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa
    30361 gcaatagttt ctaggattgc tttcctccac aaactttttt tacaaaaaaa aaacggcaat
    30421 gaatgccgct cttcttattt cgattctttt ataattctgc ttctgattca tctttggtta
    30481 gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc aacgcttcga
    30541 ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc agcaccgctg
    30601 cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga cagcgacaga
    30661 tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca tcggaatctg
    30721 cacctaaagg caggaatgat tcgtcacctt gggcttttcc taaatgcaga tttcctgcga
    30781 tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata ctattataga
    30841 tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt ttcagtaaag
    30901 cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc tgacgccact
    30961 gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt gcttcttttg
    31021 ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg tggttatcga
    31081 taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag aaattggtat
    31141 ccactattac ttttttcatc tgttcacacc tcttgattag aataattgct tgatgaatag
    31201 atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt tgataaatcc
    31261 ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga gccaaatggc
    31321 tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg taccgatacc
    31381 ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat gatcagccat
    31441 ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct cttgatcgat
    31501 actcactagg aaaaaatctg tttctttatc ttttagctct tctgtaagtt tttctagtgc
    31561 ataagcttgt gtcaagtaat cagctaaatg ctccggtaat tatcttttcc aaatgtatct
    31621 gtaaatgttt cgatactaat ttgttgtagt aagtctacat ctgaaggcgt catttttcga
    31681 atttcgtatt tattcacggc ttcttccttt caatagatcc ttttattgcc ttttttgaca
    31741 aaattccaat cttcgctaac attcttgcat actttattta aaagatattc caattgtttt
    31801 gcttcttcgt cagaaagacc atttaatgcg actgcattgg agtagttgtt ttctcgaatg
    31861 atgaaaggat agatttctgc tcctttttta gtcggataga gtttcttgat ttttttattt
    31921 tctttatctt ccaaacgttc gatcatccca ttggattcta atttcttgat tgctcgggca
    31981 gtcgttgtac gatctacttt gatcatttct gctagttttt cttggatgat tccaggattt
    32041 tcgcaaatac gtactaaata aagatactgt cctcttgtta aatcgacttc tttgaattcg
    32101 atattgctaa tagagtctag cgctcgggca atcattccga tgtctcgaag gatttcagcc
    32161 atttcatccc acctttattt tgtttgtaag actagtttac ctctttttgt tgcaaatgca
    32221 actattttta ataaaaaaat caagttcttt tttaataact agtaaagtat attcttttct
    32281 tcttttacga aaaagctcaa tcacaataga tctggttttt gttttctaaa ataagtaact
    32341 gtttcttcgt tgttcgcttt tctgatagct ttggcaactc ttctatacta aaaaatccca
    32401 tgttggaagt ttcattattc tcaataaact tggcctcttc accgtggatc gcacaagcaa
    32461 aaacaagttt ataatactga aaaagctgtg gaatatcttt ttgtttattc gtatcaaaaa
    32521 ctgctcgcaa ctgagtagtt tctactgtta atcctgtttc ttcatagact tctttacgca
    32581 cattttcttc aggagacaat cctatttcag caaatccacc aggaagtgac cattctttcg
    32641 tccgtttatc ttcgattagt aggaccttgc catctttttt gatataggca cgaacatcta
    32701 cttttggtgt tggatgtcct tctccaatcg ttgtgagcgc ttttatttct tcgaaagttt
    32761 cttttcctat ttcactgatc agttccaatg aaatcgtccg gatctcctca aaacgctctt
    32821 tatcaaatac atcttttcca taatatagac cagcttgaga aagtgcgagt agtcttttgt
    32881 attgagccaa cttcttgttc attctcttcc cttctttttt agcaaatgta tgactatgta
    32941 atcaagtata gaagactggt ttaattacgg caaataaata taatgaaatc tgcaataaat
    33001 aaaagaatgt taaaaaactc gagaacaaaa gacattcgac ttctctgggg ctgtgaataa
    33061 atggcgttca aaagcttgca tctgcggtaa taagccccat caaacgaaaa atatgacgag
    33121 ctattcttgt ctggctgttc ttattaattg aggcaggaca gctttttcac aacctcccca
    33181 ctaaacggtg ttctcctacc aactcctcgg tcacaagtca caatattcat caaacatgag
    33241 aagctgtttc tttgaaattg ctccttgtga ctcggagctg aacgacaggc tcacgacctc
    33301 tcggtaaacg gtgttcaaaa gccaattttt cgatattaag ccatttcttt gttacttatt
    33361 gtcattgatt tctttttcta atttatccaa tagtggagtg taatccactt gagtatagtc
    33421 tgttacatca aattcatata gtgttcctaa ctggaatttg tcatattttc ggtcggcgat
    33481 gatctttttg aatgcttctt tcgtaatatg attggtccct ttcgttcgat cttccaatac
    33541 gtcaccatag tgataatgat ccatgatata gctcaaatga cgatctgatt cacgatcacg
    33601 tttgtaccga cgttgccata acacttcaaa gtctgctgtt aggcgaatcg tgatcacctg
    33661 atatccgtat ctatctgcta attcttggag tcgtgctttt tgcttatcac taaaaggata
    33721 ctcggacaca atcactttct ttcctgcttc catatacaaa tcaagtgctt tgtaatagaa
    33781 aggataaact ttcgtccttt cttgttccgc ccgttcttcc aaattgttaa acccgatgga
    33841 ttctgcatag tattccttga tttcatcgag cgtgatggca tacatatctg gaaatcgttc
    33901 ccgtagttta ttcataagat atgtttttcc tgtaccagga ctaccagcca gaagaatgaa
    33961 atactttttc atctcattta tttcctaagt taattggact ttccaagttc ataaacagtc
    34021 caatcttatg cttgacaatt tcttttactg ctttatttgc tggaatcaca ttatggcgaa
    34081 gagacttgtt gatttctgtt tcactaaagg tttctttagc tactttcgtc cagttgacta
    34141 aaagctccgt tccaacattg aatttgcgga tcccgttatt gatcaattca ggataatctt
    34201 cttctttcac acctgttcct ccatggataa ctagggggac atcaactact gcatcgattt
    34261 ctttcagcaa gggaatgttt acttctgttt ttgatttgaa ttgtccatga ttcgtaccga
    34321 tagcaatagc taatgcatcc acgcctgtag cttctacaaa tttcactgcg tcttccggtc
    34381 ttgtatatac cttgtcattt tcagcgacat ggattccttc ttctgtaccg ccgattgttc
    34441 caagttctcc ttctacggaa acaccgtgcg catgggcata ttctactact gcttttgtct
    34501 tcaagatatt ttctttgaaa ggtagatggg acccgtcata catgacagaa gtatatccgc
    34561 tatcgattgc ttctttgata tcatcaaagt ctcgggcgtg gtctaagtgt aagactgcat
    34621 caaccatttc ttcttctgca atagctgtca ttacattgac taacacatgc atgccgatat
    34681 atttagcggt atcgacactt gtttgaataa tgattggcga acccatttct tttgctgcgc
    34741 ctagcatggc aggaagcatt tctaggttat gcgtattaaa agctccaact gtaaaattca
    34801 actcttctgc tgtttttgtt acttctttca atgttgtata catcttttat tgccacctta
    34861 tctttttatt tgtttccttt gatcgttact tgttttgcaa tttgtcgcat ctcatccatt
    34921 ttgcccatgt agtaatcgat cccttgatca tcaccagcac gagcagcatc tgcacgcttc
    34981 tggttataga ggctcatcag ttttttatac ccatctccga tcgtctgttt attttccaag
    35041 ctcttttcta aatattggat ggcttgatcg ttctcatgca attcagaaaa tttaagtcca
    35101 acttgttcat aaagttccgc taatttatgc ctatcttggg tagtggaaat ctcttgtttc
    35161 aattgtgtaa tctctgattg aatcttttcg gtcgcttctg gcgatagggc tttttcttct
    35221 tttgccagaa cttttttcgg ttctttttct tttttcttaa aaaatccaaa catcattttc
    35281 cctactttca attaaaacgc tttcaaaact gggcttaaga tccaggcata taagagtgct
    35341 gcggctactg tatctacatc ggttgctgta gcattgatga atcccatcga attaaagatc
    35401 gttactagca aagcgggcaa taatgtaata aagaaaccat gagcaatacc gccaatgatc
    35461 gctcctcggc gtccgccaac tgcgttgcca aatatccctg ctgtccctcc ggcaaagaaa
    35521 ttggttagca taccaggtaa aatcatcgct aagccgaaca tgggcaaagt aaacatggca
    35581 ataatcgtac caatcgttgt cgtaatgaaa cctaaaatga cggcatttgg gctataagga
    35641 aagaaaactg gacaatctaa ggcagggatc gcatcaggaa ctaatttcat agctatccct
    35701 cgaaatgccg gcacgatttc acctaacagt agacgtacac cagctagcaa tatatacaca
    35761 cccactacga attggatggc ttgtaaaaag gcaaacatga tatagttttg atctcctgat
    35821 aattcagaag cgaatggttc gcctgcaaat aaaacagtga tgatatatag cgggaccatc
    35881 acgaccatga cagacaaata agtatcttgc agaaattcga aatgtgtcgg caacttgata
    35941 tcttcgatcg actttttatt ttcgcctttc tcaccaaaaa gcttagcaac accggcttca
    36001 aataagtacc cgatcgtaca aaaatgacct aaagcaatat catttgatcc agtgatttta
    36061 cgaatgatcg gttgcgctac tgccggcata gcaatggcga aacaagctcc gataaaacca
    36121 ccgaccaaga tcaatacgat ccctcgcaga ccggcaaaat agccaaagac tgtcgtcatc
    36181 gttgccatcc ataaaattgc ttgaccagtt aaaaaaatgt acttccattt tgtgaaacga
    36241 gccaaaataa tattgaatac aaaaatggct aagaacgtca gtgcaatatc tctacctaaa
    36301 cccaaatcat tcattgcttg atcattgata gattcaatag aagggatgat cccttgcata
    36361 tgaaatcctt cagtaaagat tttcccgaaa taagttaaac ttccaacgat gatgctcgaa
    36421 ccggcactca atacttgaaa tcctaggagt gtttttaacg tgccagagat gacttgtcct
    36481 gctgatttct tctgcagtag tagacccaac atagcaatca atgcaatggt gatcgatgcc
    36541 tgagtcaaaa tattttcgat gataaaattg ataacgctca tgtttttacc ctcttttctt
    36601 tttgtattta gataactccc ttatcttgca gaactggggt gattttttct tcaatttcat
    36661 tttttgaaac aatatttttc aaatagatca tcgccgtttt aggatcaact gcgaactttt
    36721 cgaactgcga acgaaaattt tctgctgtga tgatcacatc tggtttcatg gaaactgcgg
    36781 aagaaatatc acaatggtcc agtttggctt ctactcctaa t
//
LOCUS       DAPBBR010000027        33507 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPBBR010000027 DAPBBR010000000
VERSION     DAPBBR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.027"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..189
                     /locus_tag="RD488_001457"
     CDS             <1..189
                     /locus_tag="RD488_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7657539.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1585)
                     /locus_tag="RD488_001458"
     CDS             complement(1055..1585)
                     /locus_tag="RD488_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HDT7657540.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1582..2199)
                     /locus_tag="RD488_001459"
     CDS             complement(1582..2199)
                     /locus_tag="RD488_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7657541.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2781..3002)
                     /locus_tag="RD488_001460"
     CDS             complement(2781..3002)
                     /locus_tag="RD488_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HDT7657542.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
     gene            complement(3180..4712)
                     /locus_tag="RD488_001461"
     CDS             complement(3180..4712)
                     /locus_tag="RD488_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7657543.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4848..5933)
                     /locus_tag="RD488_001462"
     CDS             complement(4848..5933)
                     /locus_tag="RD488_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7657544.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(5948..6667)
                     /locus_tag="RD488_001463"
     CDS             complement(5948..6667)
                     /locus_tag="RD488_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7657545.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6664..7974)
                     /locus_tag="RD488_001464"
     CDS             complement(6664..7974)
                     /locus_tag="RD488_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDT7657546.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8001..8591)
                     /locus_tag="RD488_001465"
     CDS             complement(8001..8591)
                     /locus_tag="RD488_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HDT7657547.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(8909..9970)
                     /locus_tag="RD488_001466"
     CDS             complement(8909..9970)
                     /locus_tag="RD488_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7657548.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10538..11605)
                     /locus_tag="RD488_001467"
     CDS             complement(10538..11605)
                     /locus_tag="RD488_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7657549.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11625..12104)
                     /locus_tag="RD488_001468"
     CDS             complement(11625..12104)
                     /locus_tag="RD488_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HDT7657550.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12121..12582)
                     /locus_tag="RD488_001469"
     CDS             complement(12121..12582)
                     /locus_tag="RD488_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7657551.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(12596..13846)
                     /locus_tag="RD488_001470"
     CDS             complement(12596..13846)
                     /locus_tag="RD488_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HDT7657552.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14224..15675)
                     /locus_tag="RD488_001471"
     CDS             complement(14224..15675)
                     /locus_tag="RD488_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7657553.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(15996..16760)
                     /locus_tag="RD488_001472"
     CDS             complement(15996..16760)
                     /locus_tag="RD488_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HDT7657554.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16788..17486)
                     /locus_tag="RD488_001473"
     CDS             complement(16788..17486)
                     /locus_tag="RD488_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HDT7657555.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17498..18277)
                     /locus_tag="RD488_001474"
     CDS             complement(17498..18277)
                     /locus_tag="RD488_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HDT7657556.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(18293..19237)
                     /locus_tag="RD488_001475"
     CDS             complement(18293..19237)
                     /locus_tag="RD488_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7657557.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19283..20062)
                     /locus_tag="RD488_001476"
     CDS             complement(19283..20062)
                     /locus_tag="RD488_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657558.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            complement(20442..22517)
                     /locus_tag="RD488_001477"
     CDS             complement(20442..22517)
                     /locus_tag="RD488_001477"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDT7657559.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(22519..23436)
                     /gene="glyQ"
                     /locus_tag="RD488_001478"
     CDS             complement(22519..23436)
                     /gene="glyQ"
                     /locus_tag="RD488_001478"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDT7657560.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(23822..24640)
                     /gene="recO"
                     /locus_tag="RD488_001479"
     CDS             complement(23822..24640)
                     /gene="recO"
                     /locus_tag="RD488_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDT7657561.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(24783..25682)
                     /gene="era"
                     /locus_tag="RD488_001480"
     CDS             complement(24783..25682)
                     /gene="era"
                     /locus_tag="RD488_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDT7657562.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(25697..26092)
                     /locus_tag="RD488_001481"
     CDS             complement(25697..26092)
                     /locus_tag="RD488_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HDT7657563.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(26076..26552)
                     /gene="ybeY"
                     /locus_tag="RD488_001482"
     CDS             complement(26076..26552)
                     /gene="ybeY"
                     /locus_tag="RD488_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDT7657564.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(26581..28773)
                     /locus_tag="RD488_001483"
     CDS             complement(26581..28773)
                     /locus_tag="RD488_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDT7657565.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(28797..29768)
                     /locus_tag="RD488_001484"
     CDS             complement(28797..29768)
                     /locus_tag="RD488_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDT7657566.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            30473..31852
                     /gene="brnQ"
                     /locus_tag="RD488_001485"
     CDS             30473..31852
                     /gene="brnQ"
                     /locus_tag="RD488_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7657567.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            32134..33474
                     /locus_tag="RD488_001486"
     CDS             32134..33474
                     /locus_tag="RD488_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7657568.1"
                     /translation="MSYSEFTKELLDILDLNLIFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTILRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPLSMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKRDRRS
                     KHLKKYWRLLQKNAWELKGQHRYWRPSFRDHLTEAEIVDRLLSYDDSLKRGYEVYQDF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYQERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT        10084 a         6867 c         5059 g        11497 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgcaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acctataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
     1861 taactctttt gttccagttg ttgtattata cttataaatc caccagtctc ccataacatc
     1921 agataaagga tttaaccaaa ttgttcgatt gattaatgtt gtaaataaaa tcatcgcagt
     1981 atagaatatc aaagcacaaa cttttctata ttttctatcc ttctttaaat gaagataaag
     2041 ttccattagt atacgtttat agccctcacc tgcagcaatg ccatctgttg catacataaa
     2101 atagaccagt cctaaaattg tcaataaaac agcaaaccca aagggttcat ataatttata
     2161 taatatatct gtaataattt ctgcaatcac tattatcata attatttctc caatatcaag
     2221 tatacactta tcgcttccaa ttacacatga tcatattaga gtgtattatc acattctcta
     2281 atattcaatt tatttttcct aaaatattcg aaataatcgt cttgataacg agtaagtatt
     2341 tttatacgat tgataacata gtaacaatat ttttaattat agtaaaaaat catctgcctt
     2401 tttcatccac ctaatcttat ttttcatttt attcaacatc cttaaataaa cttccgttcc
     2461 taagctctat aatatcttct taaaaaataa tattatggtg tcgttttcaa actcgtaatc
     2521 ttttacattg gaaaaataca tacttttctc aatgtagcaa ctcctatctc acagtattca
     2581 aaaattcttc aatattatga aatacttgtg catgttcttt aaataccttg tcagtctgtt
     2641 tataatcccc tactaaattt tgcattgctc ccaactcttc gacaaattgt catctccatc
     2701 tgtaaacagc cctaaaaact catataatgc tttttcatca atatttttcc catattattc
     2761 tcggtatagt ttcacaagtt ttacggattc ttcatattgt ttatcttttt ataatattca
     2821 tctagggaca taattacttt tgctagattt cctgcaacaa cacaatcgtc tgatacgtcc
     2881 ttgtttacta aactatttgc acctataact acattatttc ctatatgtac accctttagt
     2941 attctagact tcattcctat aaaaacatta ttacctattt tgatcctctc cgatgatccc
     3001 aaagcttctc catactactt ttaaaaccga tcaatcataa acatgagtca aaattgtaac
     3061 tccttcatat catctccaat ttcaacaaga gtcttcgttg gaacaaaaac tatacatcgt
     3121 tcgcctattc ggcagcctaa aaattgtagt tactttatat atcattctga tgtctcttct
     3181 catcttttta ccaataccga cgtaagaact ttcaaaatat acttaaactt cttattacgg
     3241 atattaaaca gaagaataac taaaatcgat atgacaaccg atataactaa atttatcact
     3301 aaacttatca ctttgaaatt tccgatatta acatacgaac aagcaaaata acttaaataa
     3361 gaagcaacaa aagctattac acacaaactt atgagcttcc aaacatattt acctgccgat
     3421 tcaaatttaa atatattttg gaaaacatta tataataacc agggtaaatc aaccaacaat
     3481 actgaaacaa tggttgccgc caaaactcca tataatccga accaattaac gaggatgata
     3541 tttaatacaa tgtttatcat tgctgtaatt aatggtctaa acctgtctgc gtaccatatt
     3601 ccagcagcat ctttgtataa cccaattaac tgatcaattt catataagaa aaaatgaact
     3661 atcataaata taacaaatga aatactcata agattatcac ttcccaccca gataatcatg
     3721 aacggctgaa ataatgtaat aaagcatgca caactaattg ccagaaacca acctataatt
     3781 gttgtaatat cacaaaaatc tatataattt ttttcttgac tttctacaat aagactgtta
     3841 cctatacctg ctatacatga ttcataaatt attgcaaata tactcattat ggcagaaata
     3901 ataaagtaat aattctgata aatcgcaagt actgaaagac ctaagaaaga tgaaataata
     3961 attgaatctg aagatcgtaa tattgtaccg cctaccttgt ttgtaactaa tccttttact
     4021 ttttttataa tatcgtcaat agtttctttc tctaactcac caacaggagt ataatcagga
     4081 tacatctttt gagaaacaac agcacacatt aagttaagaa ctatttgtcc caaaatagaa
     4141 gccaataaat acaaatagta attttttaag aaaatcagaa catatgcctg cattacaaat
     4201 tggaatgtaa aagtaattag catagacacg ttaattacat catttctttg atgtgcatat
     4261 attagactct ttctatatga aaataaccaa tacgacaaaa cagtatttat caaatacatt
     4321 aaatacaaaa ctgtcatatt taaatttcca ggaatcgaac ctttaactaa aaatctcaaa
     4381 aaaggaatgc ataacaatcc taatgtaaac actatccatc caataattga aaagtacttt
     4441 ttatatgcgt tcagtaaagc acaaatctct tttctattgt cttctgctat aggtttatac
     4501 atacttacag ttagtgcagc acctattccc aattccgcta aatttaacat ttgaaatata
     4561 gatgtgaaca ggttgttcaa tccagcatac tccattccca tctgataaat cataagtgta
     4621 cgcataaaaa agggaatgat aatctgatat aacttaaaaa ttgttccagt aattatattc
     4681 cttttagcat tttgtttacg attaattatc atatcatatg gctccaaact ttctattttt
     4741 tattgttacc taatactata taatttctaa aatcttgaaa tgtaataggt ttcttctagc
     4801 tctttgatta attacgctaa ttttcatgtt tggacaacca caaaaaacta tacattttca
     4861 atcaaagcaa cccattgttt tgtaatttct ttcaaattaa atttttgtac attattatat
     4921 gcgttcagtg acattctcat tgctaaatca gtattcttag taaacattat catgctctta
     4981 gctaattggt ctatattctt atcttcaacc aacatcccat taaaattatg atgtaccaaa
     5041 tctctcggac cagttttaca atcataagaa ataactggta atccataaga ctgtgcttct
     5101 aatataacca taggaaatcc ttcataaaca gaactaagca cataacaaga tgcagattta
     5161 taatattcct ccacatggtc tgaatgccct gctatagtta ctctttgcag atttaaatct
     5221 tttatctgct ggcgaagatc tttttctaat tcaccttttc ctacaatgat aagatcccaa
     5281 tcatctactt ttttttctac aattttccaa gcacttatca tgtcagcaaa atttttctct
     5341 tccactaatc gccctactgc aagaaatctc tttttatcat aatgatattc gtactcgata
     5401 ttagatatac acggatttgg catagttata acaaaatctt ctgataaact atattcatca
     5461 atatgttttt gacgatcttc ttctgtgaga accacaagcc tctttgcata tttttttatc
     5521 aattttttag ccttgaatct cttcttttct ttcagcattt ccattgtcca gtaattaaaa
     5581 tgttcccaag aaatcaattt gcactttgtt cctttaattg cccttgtagt atacaaagac
     5641 aacaaagtat caatatcaat tactatatca aattcatttt tgcatatata cttgtgcaat
     5701 ttccaaaccg gatataaata agttctatat aattttccct ccgttttagg atttaacata
     5761 taatcaacct taatcgtctt atctaaccca aaataaggct ctccactatt ccaaaagctt
     5821 aaaatagtga catcataacc taaatcagac aagctattgg caataatact ccctactctt
     5881 tcagttcccc cagaacgaga aattacacca ctaatgaaac aaattttctt caaagtactt
     5941 ttctccttta taagtgtaaa aattttttca gtgcaagtaa cctgttaaat tttttttgtc
     6001 caattgttga ttttaatcta taaacaaatt tttgtttagg tgttttccaa gatgcattat
     6061 attgatgaat gcttattgta ttactagttt tataaatttt tccagtatca taatccttgg
     6121 cagcaaaata atccgtagga tagatatgca ggccatttat tatttgttcg ctgttatcgc
     6181 gaaccaatcc aatagattca agataatctg taatataata cggactcggt ttcaagttca
     6241 atgtaccatc attttgataa aaacttaatg aatcgtaaat atcccttaaa cctttaataa
     6301 cagaatgtcc ttcttctgca ccaaaaccaa taccgccatt aacccagatt tccccttcaa
     6361 atcccatata ggcatgattt tcacgaagta tatctaacga cttaattagc tcaacatctg
     6421 tatctaaata aaatccacca tgattataaa taatatcaaa tcttgcataa tctggaacaa
     6481 aaccccattt acgttcttta tatgcatcgg ccatataacg gttcttattt aaatcataat
     6541 ttgattcatt ccattcaata atctcataat cagggcaata ctttttccag ctttctatgc
     6601 actttctatc ttttttcgga agtggatttc ccccgaacca acagtaatgt atcttcttag
     6661 gaatcataat atctctcctt ttgtattttt ttcactataa taatgctctt tccttttcac
     6721 aacttcaggc atggctaaaa tcatataaat cagtggcccc gttgtttcac ccctaagtgt
     6781 tgtgttatac acaaaaaaga ataccgacat aattgcaata actttaacaa gacttgcatc
     6841 tttatccttc ataaaagatc tttttgcatt gaaaaatgtc tttattataa aaaataggaa
     6901 tatcgaaact cctaatattc caacttctat aaataaccaa atatgatgaa aatactgata
     6961 atgaagatta ccaaacgatt tataaaactc actgacaaaa aaattggtaa actctgcatt
     7021 gccaatgcct actcccatta ggactaatct aaaattatta ttaaatattt catctactac
     7081 tctagagata ccagttattc gatttaaatc accaacacca tcatatccag aatctcttga
     7141 cgcatattct aaaagacctt gaattgtgaa attatcagca tagctttgtc cattatcgtt
     7201 caatgtaata aatattgtta taaaaaagga taatactatc gacacaagta ttacgcatga
     7261 taatatcttg atcactactt taaaatcaac ttttaaagtg aatactattg caacaaatat
     7321 tataaataat tcaggaataa aaactttcaa ttcagctaat gcagacataa aaagtgctgc
     7381 acaaacacat aaaataaaat ggatgaaatt tttttctccc ttgaaatatc cgattgtaac
     7441 aacagtaact gtcacacaca aaattaaatt caatggcata ttacaacctg aataattcca
     7501 aaaaactcca cctatcatat ctcctacaat tgttccagtt ggataggtga ccatgaatct
     7561 ttcaattaaa caaagtggca gtgaaatcca gaataatttt tcaattatag cgaatacttt
     7621 atagtaatct ttaattgtta aatatgttgc acaatttata tatactatga acatacgagt
     7681 gttatttcgt atcccccaga taatcaatcc tatattttct aaattaataa ctgagctaca
     7741 aatagaaact agtaaaaaca aaactatcag catctcattt ttgctagcat atattccttt
     7801 tctgcgtcta aagctaagtg catttaataa cacaaagata ttaattatat ctcccaaata
     7861 taaaattgct cttggggcgt taaaagtata tacaagaact atggagattg caaaaaatgc
     7921 caacgtgaac aatgtccaat ctgctcctga ccatcttttt attgaaatac gcatcgttat
     7981 tcaccttctt tcgctaaaaa ttattctaaa aatacttttg ttaaattaac ataccctatt
     8041 atttttgccg gtacacctgc aagaattgca ccattctcta gacaatcttt gataacaata
     8101 gctcctgccg caacaactac attgttagct atttttacat taccaataat ctttgcaccc
     8161 acgcatacac gtacattatt tccaattaca ggacacttag gatcgattcc atcatttcca
     8221 atacagttat tcccatataa gtaacaattt tttcctatta tggcgttacc attaataaca
     8281 attccttgtg tatggtaaaa tcttacacct tcatcaaata cattttcacc acactctata
     8341 ccacattttc ttcccaaact attcattctt ctgcaagaca caatatacat aatcgcataa
     8401 atgatatttt tctttctctt tgaataataa taagatgtaa ttctcattcg acgagtatac
     8461 cgccaagcgt tgtagtccgg atgtgatttc attattttta gtaattttgt gtgttgtcct
     8521 ttagattcta tatatagatt cttttccata cgaagaaccg cttttaaata ttctttactg
     8581 ctaatttcca ttcatatctc ctattaattc aatttatact taacaatttt attcggattt
     8641 cttgcaacaa gagcatcatt caatgctact gaatctacaa cgatggatat gttatcttca
     8701 tcgttgattc caccggatac aatattactt ataaaaatcg taacattttt tccaaaagaa
     8761 gggatgtccg tgatgtataa tgcccatttt ccgatatttc cagttattta aacctaacga
     8821 atttttacaa tagtacaagt atcacaatca ttaatatata actggaatat aaatctccaa
     8881 aaattcacta tagtacagtt ttttatgatt aaaatctcct atttctaccc attccgctta
     8941 aatatgctaa tgttttaacc ccaataatgg attggtttag taaaaaatag ttaaatattc
     9001 gttgtttaat tggattttgt ttatatgggt atgagtgaat acaggcaatc aactcatcgt
     9061 tcataagtat cttagacaaa taggagttta aatcaaattc tttattaaaa ctagcatatc
     9121 taactgcctt ttgaatacaa gtacgacagc gtcccaacaa aagtctcctt gttttgttta
     9181 caaatatctc attttctaat atatagctta aatcgccttc aattttttta actaattcaa
     9241 tattacaatc gaactcatta tctctaaaat tatgtgtcaa tgaattatta ttattacatc
     9301 tataataata gatacaatct ttaataaaac ttgttatttt tgaatgttgc aaatatgaaa
     9361 tatggaatat gatatcttca gatatataat ccctttctga cggaaacttg atattgtgct
     9421 gttgaattat ctcagatgaa tacagcgcat gccaaactga cattggcaat ataaaatcga
     9481 ctttataact cggctcagtg ccaatcattc caagcaacac tttttcaatt atagcgttat
     9541 ttgtaaatat cgtactatca tatcttgctg gctttgaaat aatattatta tcatcataat
     9601 attcataata tccagcataa catgtgtctg cattactcct ttttatacca tttaacattg
     9661 cttcaatata attagctgca acaaaatcat cagaatcaat aaaagcaaca tattttcctt
     9721 ttacatgttc aagtcctgta tttcttgcca atcccaagcc agcattattt ttatgaataa
     9781 tacgaatcct tgaatccttt aatgcatagt cttcacatat tttattagat gaatccttag
     9841 atccatcatc cacaattata atatctaggt tcttatatgt ttgattacac actgattcca
     9901 aacaacttcc tacatacttt tcaacattat atacaggtat gattacacta attagatcac
     9961 tcgaattcat ccttctatcc tttcactcac gttttctcaa ttagtcaatg acggcatcaa
    10021 cgattttctt aaattctctg aaaaaaatag actctgatct tgatgatgtg aatgacatac
    10081 tatcttcttc tagaaaaatt atttccttta aattatttat taaatcaata atatgatcct
    10141 cgtaagtatg ctttcccttg gaataatgaa aatatacttt tgtattacac aatattgcaa
    10201 ttttatttct taatatgatt atttcactca ttcattactg ccacatatac acaacttata
    10261 accaccccct gcaaagttta gggtaagtta tcagataata tcttcctctt catcatccag
    10321 aatacaaaat ctatttattt atagaaatat cattaatgtt tttatataat gtaccgtgct
    10381 tgtactcttg ctctattaca agcactaaaa cactactatt catttgaatt cttacacgga
    10441 taaaaattta catcgtctat ttcaatattt tttctctcta ttttattcac ttaataagtt
    10501 cattacataa tcgaaacatt ttttattttc cttgtcatca ctccttgctc cctttttgat
    10561 acagatttaa aattctatca aagaaatttc catcgttaaa tttcgttatt gccaaatcct
    10621 tcgaacaacg tgaaaatttt acgtatttat ctttatcatt gatttttagt attgcagatg
    10681 tcaacgctga tacgtcacca ggttgaaaca aatatccatt ttctccatca cgtactgctg
    10741 aagaaatatc tcctacatct gtagcaatta caggcattcc ataagaaatc gcctctagaa
    10801 tagatatagg caatccctcg ttataggacg gtaaaatcat cacatttgat cttctatagc
    10861 actcctcctt tttttctccc acaacccaac ctgtaaattc aaaatacgat tgcaaattat
    10921 attcttctat caattctttg agcgatattt cttcatcacc tgctccagca atctcaaaaa
    10981 taaacttttt ttctggatat tgttctgcaa tgtttttaac tgcttctacc aaatcgtgta
    11041 caccttttcg ctttatcaaa actcccataa acagaaatcg gcacattttt gaattccact
    11101 ttatggtata ttctggaact acaatagaat tttctacaac aacagtttta caatttggct
    11161 caatttcttt aattatcttc ttccattttt ctccaagtac aatcgtggaa tcagactctc
    11221 ttaacagcaa gcgaatctga ttttgttttt ttacagaaac actatcatac cattttttaa
    11281 attccgatcc atgaagatgg atgattacag gaatatttaa taatctaaac cacttattca
    11341 gcacatattt cctactaaaa ctccctctgt acgacatgtg catatgaata atattaggtt
    11401 tactcaataa agagatacct ataattttag caaatgcata cataaaatat aaagatttaa
    11461 atattgcatt tccaccctta taactcggta taaaagtcat ctcgatattc tttttttccc
    11521 aattaaaatt gagcatttgt gtaattatac ttgtaattcc accttttacc gagctgtcat
    11581 taccaatcat aagtactctt tgcataacgc tttactcctt atatttatat tttttctatt
    11641 aatacctcta tcgaattaat aatcgtttcc gtgttagata catacttgtt aaacatccga
    11701 actcttgttt ctttaacggc atcttctaaa ttttctaatt cataacaagg atagataata
    11761 ttcatctcat caaattgtct aattaactgc agttggtgat catcgacatg ctcaccatac
    11821 ttagccaatc gaggaacagc aatgaccctt ttaccttttt ttacggcccc aattatagca
    11881 cctgtacctc catgagtaat caccatttct gctttttgca tagtttcagt aaactcatcc
    11941 ctatttagaa atgctttata ggaataattt agtggtttat aatcactata accactctgt
    12001 gcaaatgtac tttcgattat tactcctttt tcaattaaat catcaatagc ttttaacaat
    12061 ctatcaaatt gaaatttttg tgaacctaat gttataaata tcattttttt ctcctattat
    12121 ttaatatatc ccacccaaat aaatagcatt aggataaaat tgtagcatag tttcccactg
    12181 aacataaaat tgatctgcaa aatgatacat caattttcct gtctgagtag ggctggttac
    12241 ttttgcaaac gattcaatat aaatcagttt ttttcccatc atttttgtta ttaagcagat
    12301 agggatcata gctaaaacac ctgtacaaat cacgagatcc ggtttttcct ttatatatat
    12361 aataattgat ttgaataaat taataagtat agtacacaaa aaaaactttt cttttctatt
    12421 tacttgtctc atgtagtacg ttttttcgcc ttttgactca gctgaatatt ctgtctgttc
    12481 tgttataaca aaactctcat acttctccat cagtggtttt aacatcatta actgttcata
    12541 atgcccccca gaggaagccg caaaacatat ctttttgttc atattaacct ctctatcagt
    12601 cacgctgaaa aatatctcta gtgtaaactt tttctttaat atcatccaag caggtatcat
    12661 atcgattggc aataatagaa tcacacatcg ccttaaactg ctctaaatcg ttgataacct
    12721 tacttccgaa aaaagtctct ccatctttca gtgcaggctc ataaatcacc acagtcgcac
    12781 ctttagcttt tacgcgcttc ataactccct ggattgaact ctgacgaaaa ttatcactgt
    12841 tgctcttcat ggtcagccgg tatataccga ttaaaactgg attttccctg ttgacatcat
    12901 actgattata ttcagcgtag ttgtaatagc ccgccatctg aagaacacga tctgcgatga
    12961 aatccttacg ggtacgatta gattcaacga tagcctcaat caaatttcca ggaacatctg
    13021 catagtttgc caacaactgc ttggtatctt ttggcaagca ataacctcca tatccaaagg
    13081 atggattgtt gtagtgagtt ccaatacgag gatcgagaca aacaccattg attatctgct
    13141 gagtattcag ccccttcatt tcagcataag tgtctaattc attgaaatag ctgactcgca
    13201 gtgctaaata ggtatttgca aacagcttta ctgcttcggc ttcagtgaat cccataaaaa
    13261 gagtatccac gttctcctta attgcacttt tctgcagaag tgttgcaaaa acatgagcag
    13321 catttaacaa gcgctcatca gtcatatcag taccaacaat aatacgagat ggatacagat
    13381 tatcatataa agccttgctc tcgcgcagaa actctggact aaaaataatg ttcttactcc
    13441 ccgttgtctc acggactgat tcagtgtagc caacaggaat tgtagacttg atgaccatga
    13501 tggtatcagg attcacgtcc atcacaacct caataactga ctcaacagca gaagtatcga
    13561 aatgctgagt acgactgtca tagttagtcg gtgtagcaat aacaacgaaa tctgcggatt
    13621 tataagcgct ccttgcatcc aaagtagcag ttaagtcaag ttctttttct gtaagatact
    13681 tttcaatata ttcatcctga attggagact tccgtttatt aatcagttca atcttttcag
    13741 ggataatgtc taccgcggtt acctggtgat gctgcgccaa tagtgtggcg atactcaaac
    13801 caacataacc ggtgccggct actgcgatgt tgtacttttt cttcacaata tctcctcttt
    13861 cctctcttaa gtatggagaa tgttactcct acggctattc atcatgtcaa aataacacag
    13921 cttagaatgt tgataaaata attttccaga atgtgataaa atctctttca tttataaacc
    13981 acacatctaa ttttatctat tctccacaag acatgtagag tattctttaa taacaagata
    14041 cgaccttact aaatacttca aaaaattatc atatttaatt cataaatata aatcttcatt
    14101 ttaaatgtat gcccaaaaat ttatctgtaa tgcgtcatca aaatctagat tccaaatctt
    14161 tatcaatttt tatccactca ttctaccact ttagtaatat tttctattta taacactttc
    14221 gtcctacatt gatccccccc tctgaagtac agtttttact gtcttaaata aaattttaaa
    14281 atctaacccc atactccaat tttttatata ttccgtgtca agttttgcta cttcttcaaa
    14341 atcagtaata tcacttctac cacttacctg ccacattcca gtaattcctg gcttaatagc
    14401 aattcttgca cgatgatgat aatcatattc ttcatactct gatttaaggc atggtcgaaa
    14461 tcctataagg ctcatctttc ctgttagaac gttgaaaaat tgagggaatt catctaaaga
    14521 cgtggatcta ataaattgac cgattcctgt cttttttgtt ccatctggaa gtattttatt
    14581 tccgataatt cttggatcaa actccatctt aaacataaga ttattgctca tcttattttc
    14641 tttcattaat tctacttttc tttcttctgc atccatatac atacttctaa acttatacat
    14701 cttgaacggt ttaccattct gacctatacg ttcttgtgca aagaaaattg ggcctggtga
    14761 attaatataa ataagtggag caataaagat aaaaataatt cccgttgcaa tacatccaac
    14821 aatacctgca agaatatcaa ttgttcgttt tataaatgcc tgttgagttg tcataacatt
    14881 gatacttgtt gtaagtactg tatattctcc tatacgacca atagattgtt ttcccaaagc
    14941 actatctgat acttttgcaa gattcaaatg tacagtaagg cccatttcag agcatcgttc
    15001 aataaattct ttcatacacg aagtactttt attcaaaata ataaagactt catctaccca
    15061 tccctgacat aagtaatccg ctgcattttt ggaatcagaa acaactgtca ctccctcaac
    15121 atcttcacca atcatgcttt tatctatgat aatgacacca tttattttat acattttata
    15181 gttatgctct ttcacattac gaataactac ttcagcaata ctactagatg taactataat
    15241 aagtgatttg ttcccctcat ttttcatttt atgtttcaag taatgtttcc ataagaggcg
    15301 agttatatat gtaattacaa cgtataaacc tcccatcaag aaaagaacga ctctagaata
    15361 atcatttcca ccctgaacac taatgagata caaacttcct aacagcacca acataatcgc
    15421 ttgctttaca gaagaagcaa attctatata gtaccctctt tttaatacac ctctatatgc
    15481 ttcaaacatg aaaataacta aaagatctgc cagttcaatg aagactgcca tgttttgata
    15541 cattggaatc acataaggat tccaatctac ctggcgtaag acatacgata gataaaaagc
    15601 aagctggata cacaataaat ctaaaataat aaaatcaata tgtttaaccc atccccttga
    15661 acttttcttg tacattcctt tttactcccc tctttttaat aaaataaatt gtattacttg
    15721 ttttctctcc taaatatctt tctgaaggat tattgactcg acaaattggc ttgtggatat
    15781 tcttatatat agaacatccg taagccaact taaaactcct taacaaaatt tttttactca
    15841 tattgtagat caaaacaagt atccaagaaa tcatatttta tttctttttt ctgcttactc
    15901 aacaacagct aaaagaaaaa tcatcataaa caaattcaac taagccaacg atccccttgt
    15961 gaaatcaagt tttttcttga tttacgaata aagagctaaa ataaaccaaa cttcttcttt
    16021 tttacctctt catagactgg ataactgatt tcatccccgt tgatcagatc ctttgcgact
    16081 tgtttcatct gtactacttt ttccttacca aagtcctttg caatctgctc atagcactct
    16141 tttaagtaaa aggtgcgctt agagacccca tgggcatcag aagcagccat ctgcacgaga
    16201 ttatgtttga ccatcgtttt ggctgttttc tggatgtctt tgccaaatac cccaacataa
    16261 cttggcgcag tgagttgggc caaacatccc atatctagga acggaagcaa atgatttggg
    16321 tcttcgcgaa aatgcacgtt gcgttctgga tggacgatta ctggtgtctt tcctagttct
    16381 aacaactcaa aaaaaagccg ttctgcatat aacggcactt ccagtgtcgg aaattcgatc
    16441 agaagatatg tatcatctaa atctgtaaat aatatttcat ctcggtggat gtcttcgatg
    16501 agcgttccgg taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ctgtcttttc
    16561 tctaattcgg cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat
    16621 tttccattat tgtggtgtgg tgtgcataaa atatgcgtga tgccttgctg aatcgctttt
    16681 tcagccattg caatacttgc ttctaagttt tctgccccgt catcgattcc tggtaggata
    16741 tggcaatgta gatcgatcat ttctcttgtc tcctctcttc ttattcctta atttccgtag
    16801 taataaccag catctttgct atgttctgct ccgttgtaca caacacctaa gactcgtgct
    16861 tgtaccatct ccagcagttc ttttgcttta gtcaaggatt ctttacgtga catattttca
    16921 cgtacgacca ataaagtgcc atccgttttt aaagacatga tctgtgcatc tgttacggct
    16981 actactggtg gcatatcgaa tatcaccacg tcaaataact gtcttgcttc ggataggatc
    17041 tgatccattc ttggcgagct taacaattct gatgggttgg gtggcttagg tccactaggc
    17101 aaaatcgaca agttctcgac tggcgttcgt tggatcacat ctgctacact tcctgatgaa
    17161 ctaagtgctg tacttaatcc actggcattg ttcagctgga atgtcttata gacgacgggt
    17221 ttacgtaaat ctgcatcgac tagtagaact cgttgacctg atttagcaaa aacgactgca
    17281 atgtttgctg cagtggtgga tttcccttct ccaggacctg atgaagtcac gacaatcgtt
    17341 ttgatttgct gaccagctgc ggaggcaaac tggatattcg tccggatcgt acgatattgt
    17401 tcggcgattg gtgaagatgg gtttgttaat gtgatcaaac tgactgcatg agtttgtgct
    17461 gctttttgtt tctgtgttcg tgccattttt cttcctccta gactcttgag cggcttctgc
    17521 gtgatggggc tgttttatcg tttgtagctt ttggtcgtgc aggagctgtt ccttttttac
    17581 ggataccagc gttcaattct ttcgctgaca tttctggaac tgttcctaag attgggaatc
    17641 ctaatgtatc tgtcacatat ttttcatctt tcactgtccg atcgagtaat tccaataaga
    17701 atgccagacc tacacctacc atcattccta acattaagcc agtcattaaa ttcaatttat
    17761 tatttggcga aacaggtgtc gtattggcaa ctgcacctga aatgatcgag attttatcaa
    17821 cattcatcac atcttttgcg ttctcttgga aaacttgtga agttgtgtta gcgatctgtt
    17881 gagcagccac tgcattcgta cttattgcct gaatcgagaa catttgtgaa ttttctgcct
    17941 gattaactga gatggcatct ttgatttgtt cagcagtcat tttcacattg tcttctgttt
    18001 ctaaacgatc tttgacttca ttgagcacta aatcactgac gatcatatct ttatacgtat
    18061 tgatcatttg caggttcgta ttgacatcat tgacatttgc agtgtctgat tgtggcagtg
    18121 tcacgatcaa ttgtgcttgt gaactgtatt ttggtgtcaa gatgaaaaat gttacgattc
    18181 ctgagatggc caagccagca aacattgaga tgatgattat taccaagtgt ttgcgtaatg
    18241 tttcaaaaat ttctttcaag ctgattgtct cttccatttt ttctccactt tcctatttat
    18301 tctctagatt catttgatct tttaattctt ttttcacacg atcaagttct tgatcactga
    18361 ctttttgata ggagatatta tcttgcatga agccttctcc ttgcagctga tcttgcttaa
    18421 tcgtaccaaa tgcctcccga taatctaaag caattttttt catttcatca aagttcatgt
    18481 ctgttttcat attcgactct agagcattca aaacggattg atagttgctg acaccgttta
    18541 gactcaatac ttttttcgct acgccttcta cgatctttct ttggcgccct tgtctaccgt
    18601 aatcaccatt tgggtcttca taacgcatac gagaataaga taatgcctga tccccgttca
    18661 atgtaatttt accgattgga aagtcatagc catcttgtga gaaagtgagg tcattattga
    18721 cttcgatacc accaactgca tcaacgagtt cctttagtcc tttcatattg atagagacat
    18781 agtgatcgat tgggatgtct acatattttt gtacggtatc catcgccatg gcagctccgc
    18841 cgaatgcgta agcgtggttg atcttgtctt ttgtgtcacg acctacgatg tcgacatacg
    18901 tatctcgagg aatgctgacg atcgttgtct gtttgtcttc aggactgact gtggcaacca
    18961 tcatcgtatc tgatcttcct tgatcgaccc gacctaaatc tccagtatca atccccatca
    19021 atagaacaga gaaagattct tgtttgtcca gatcaactgg tttcgttcgt tctccttggg
    19081 ttcgttccac tgattcgtaa gttttctcaa tagaatgtga gagatccaga tataattttg
    19141 ctcctactcc tacaattgct aatactaata cgataagaac tgctaaaata atcaaaaata
    19201 tttttttccc tcttgatttt cttcttcgtc ttgccatagt ttcctccgtt tgctaacctt
    19261 gcttgaatca acgttttaac tgtcaatagc ttatattgct atagcccatt tgctgagcaa
    19321 cagtttgtgc ttttgttgcg tatgcggctc ttattttttc attccggatc tgctctattt
    19381 gactgagcgc cgtcaaatat tgatcgtaag tagcggtagc tgttacttga ccgtctttca
    19441 gcatcgtatc gaatagctga tctagttgcg tgacttgtgc aatttgggta tcagcgaatc
    19501 ctagatattg cataacgact gttttccaag cactatcctt aaaaaagctc atattttcac
    19561 gtacatgggc gacatctgca cttgccaact tttctttgat gatgacatca tccacagctt
    19621 gctgccagtt tgatacgttt ttagtaaata atttattgac agccgtctgg atcttcagtt
    19681 ttgattctgc atcctctaac tgcgttaaga ctgctttctt ttcttcttgg atcgcagcag
    19741 cttctttagg taattctgat tccttgatgt cataatcatc tgccgaaagt ttgatagaag
    19801 atagtttatg tgacaaattt gaaactgttt cttctgttat ttcaggattt aggaaaattt
    19861 tttcttttgt actgtacagc ttatctactt cttttgataa agaggtcacg gtgtcttttt
    19921 gattggtgat ggcagattct gcgtaattga tccgttgatg atattgccgc tgattattga
    19981 gatggtatcc aaacaagcaa atcacaatag cgcctgtgcc taccgccaca gtagccaata
    20041 acttgacgaa cggcttttcc atagattcac tcctaaatat tgatgataga taagtaaaga
    20101 tgtgattcat tcacatcaga atgagcgctt tttattttaa aagcataatt aaactaatat
    20161 attcatagaa atatttataa acaggttttc cctatataat cataccacat acagtttttt
    20221 tgactaggga aattcctaat ttaaaagtaa ataaaacagt aacaagatta taattaatcg
    20281 ttttcatttt tatttcctca cttttcatga gcgttttgaa aattcgaaca aagaataaaa
    20341 taacaaaaat tattaaaata gaattaataa cagctattta taacaaaaaa aacagagaca
    20401 cagcacgttt cgtgcatgct ctctgttttt caaacaaaag actattttgt gatgatttga
    20461 tccaagcttg ctaatgacaa agccatggca gctatttgac ttagttgtgt tagtcggttc
    20521 ttacgtactg ctggttcatc agccatgacc atcgtttgat caaaataatt ttcgatcagt
    20581 ggacgaagag cgacaagctg gtcgtagttt tcgtggatcg tttggtcagc aaaacttgct
    20641 ttcattgctt ctactgcttt gtgtaattct ttctctgcgt cgttttcgaa cagctcaggg
    20701 tctacttctg attgtttttc aagctgcgct tttttcgcta agttcacgac acgtgtcaaa
    20761 gcttccattg aaggtttgaa gtcttcatct gcaagatgtt gtttgaacaa ttgtgctgct
    20821 gcaaatactt ttgtcagatc tttttgttcc gcattcaaaa cagcatcgat gacatcatga
    20881 cgaatattct tcgttgtcaa taattggcgc agacggcctt tgataaagtc gatcacttgt
    20941 tgttgccctt ctgataaacc aatgccgaaa cgatccgtat ctttactgat aacatcgcta
    21001 atcgtttctt gcagaacaga caaaggaaag gcccattttt tcgattcgat gatccgaacg
    21061 acaccgtatg cttggcgacg taaggcataa ggatcgtttg acccgcttgg aatcatccca
    21121 actgcaaaga aagaaaagat gctatctaat ttatctgcaa tcgctaaaac agaacctact
    21181 gtagactgag gtagctctcc ttcactggat ataggcatgt aatgctcacg aatcgctgtc
    21241 gctacagcag gtttctcgcc tttcagaaga gcatattttt cgcccatgat cccttgtagt
    21301 tcaggaaatt cccctaccat gttggttact agatcaaatt tatagatttc agcagctcgt
    21361 tgcaaatcca tcaattcttc ctcagatagt cctacttgtt cgccaatgat acgggcaatg
    21421 acttgtaccc gttgcatttt ctcatagata ctaccgattt tttcatggaa agtaacagtt
    21481 tttagttttt caacgtattg gtcgattgaa gctttcttgt cttcattata aaagaattcc
    21541 gcatcttcta aacgagccgt caatactttt tgattgcctc gaaccacatc ttccaatttt
    21601 acccgatcac cattacgagc agaaataaaa tgaggaagca gcataccttg atcattccgt
    21661 acctcgaaat aacgttgatg ttctttcata gaagtgacta gtacttcttc aggaacagaa
    21721 agatattttt cttcgaagtc gccagaaaag acagttggat attcgactaa attgttgact
    21781 tcttctagta aatcttcgtc tagatcaata acccagtgat ttttttctgc taattcgttt
    21841 gcttgtgtaa cgatcatttc ttgtcttttt tgcggagacg caatgacgaa ttgttcattc
    21901 aatttttctt catattcttt tgcatgcgca aatgtcacat cttcgcctaa gaaacgatga
    21961 cctcgagagg ctctgcctgt tttgacatcc aagatttcga atgggattac ttcgtcatct
    22021 aacaatgcca cgatccagtg aatagggcgg atatattcaa aatcgtattc tgcccaatgc
    22081 atcgttacag ggaaagtcaa acttttgatc acccctgcta agcctgtcaa tacttctttt
    22141 gcttccttac catgagtgta tttcgttaca tagacatatt ccacaccttt taattctcta
    22201 aaagtgatag cgtctgtcgt cagaccttgt ccgcggacaa atccttccgc tgctttcgtc
    22261 cagtttccat ctgcgtccaa agcaattttt ttggctggtc ctttgacttc ttcttcactg
    22321 tccgcttgtc gttctggaat atttgttact ttgattgcta aacggcgcgg tgtggaaaat
    22381 gtttcgatcg tatcataagt caattggttt tcatctaaaa attttgctgt tttttcttct
    22441 aattgtttca tgcttggtgt gacaacatgg gcaggcattt cttccagccc gatttcaagt
    22501 aataagtctt ttgccatctt attcagcctc cttcacggtt tctggatttg ctgtgttttt
    22561 attcaacaaa gggaatccta atttttcgcg ttctgccaca aagattttgg ctacagcacg
    22621 agccatgttg cggatgcgag aaagataacc ggcacgctct gttacggata ctgcaccgcg
    22681 ggcgtctaat aagttgaatg tatggctaca tttcaagata taatcatacg ccggatgaac
    22741 aagattttca tcgatacagc gtttagcttc tttttcaaaa cgatcaaagt tgcttagtag
    22801 caagtcttgg tcgcttactt caaaagaata tttggaatgt tcatattctg gttgtttgaa
    22861 gatctcgcca tatttcacgc catcagccca ttctaaatca tagacacttt caacttcttg
    22921 gatataagaa gcaagacgtt ctaatccata agtgatctca gaagttactg gtttacaagg
    22981 cagtccacca acttgctgga agtacgtgaa ttgtgtgatt tccattccgt caagccatac
    23041 ttcccaaccc acaccggcac agcccatgga tgggttctcc cagttgtctt caacaaaacg
    23101 gatgtcgtgt tctaatggat cgattcctaa aaggcgcaag ctttctaaat aaagctcttg
    23161 aatattctca ggtgaaggtt tcatcaccac ttggaattga tgatgctgat acaaacggtt
    23221 tgggttttca ccataacgtc catcagctgg tcggcgagat ggctctacgt aagcagcatt
    23281 ccatggttct ggtccgattg cccgtaaaaa ggtatatggg ctcatcgtac ctgctccttt
    23341 ttctgtgtca taagcttgca tcagcatgca gccgtttgat gaccaaaatt tttgtaatgt
    23401 taaaatcata tcttggacgg tcaatttttt actcatctgt tttgcccctt tcaattttaa
    23461 agcgttgctg tcaaataaga atacaggaaa gaaaacgaca aaaaatccct atgtctgatt
    23521 acagacatag ggacgaataa ttcgcggttc caccctactt ccgaataaag attcggcagc
    23581 ttcatttatc gtactcgcaa gtgcctcttc aaaaatcgtt tgggtccggc tcccactctc
    23641 ccgaactcgc taaaccacgt gttttttact gatcttggtc aatgtacgta ttcattttgc
    23701 agttttcttg tttctataat agatcctatc actgaacgat ctatttaatc tatggttaat
    23761 aatagacgga actccctgtg tttgtcaaat ggttttgatt ttttgttgta tgttttattt
    23821 actattcttc tttttcaggt gtctcttttt ctttttcaga catgtctttc tctgacgtct
    23881 ttaatacgtg tgcccaagac ttcatttgat tgatgaactt tttgcttttc aaatggatac
    23941 cgacatattc atcatacagc tggtcgatga gttcacggat tgcttgtttg gtttcttctt
    24001 tcagatggat tccactaatt ttatcataag aaatagctga aaacatccga acgaaataaa
    24061 cagctcgagg atctgcatga taacggtgat cgtccatcga ccaatgtctt tcgcatatca
    24121 caccaccata tttggaagaa tagtcaaatt ttccttttgt ttccccgcat acgacgcagt
    24181 gtgtccagat tggtgcaatt ccgaagcgtt gcagtatttg gacttcaaaa atattcgtga
    24241 tgatttctgc atcgtctcct tggtccatcc gttgcagtgc ttgttgcgta aactggaaca
    24301 aatgcgggtc gtactgatga tcttcgattg ccgcatctac tagattcaat aaatatgtgc
    24361 catagccgct caaaaagatg tcttcttgga tgtgtcgaaa cgcatggaca tctttgacac
    24421 tgcttaaaaa tgacaaacct tcacttcgaa aattcccgat ataaactgct tcagtaaaag
    24481 ggagcaaagc cggagctaag ggctgatttt gccgatggat ctctttgata taaaacatca
    24541 ttttgccaga agattctgta aagattttga ctaatttatc tttttctttg taattacggc
    24601 tagataaaat caagcctttt gattctgcaa gctggctcat attctccctc ctaaaaaata
    24661 aatctggaaa agcagattct gccgatccag atcatttatg ttgcgatctt ccgcagcttt
    24721 tctcaacacg cggattttta ttcagtttat ttctatacct aatttacaag aagctcagaa
    24781 tatcagtatt cgtcttttcg gtagccgaag tcttgcagat agactttttt gtctcgccag
    24841 tctttttgaa ctttgaccca aagttctaga aagactttgt ctcctaaaag attttcgata
    24901 tcttttcttg ctttcgttcc tacttgcttc agcatttttc cgcctttgcc gataatgatc
    24961 cctttttggc tatctctttc gacaataatc gtagcctgga tatggatttt atcattctcg
    25021 tttcgcttca tcgaatcaac aacgactgcg acagaatgag gcacttcgtc tcgtgttaaa
    25081 aacaagactt tctcacggat caattcagaa acgatgaagt attcaggatg atcagtcact
    25141 tgatcatctg gaaaatattg tgggccctct ggcatttcac tgactaatac atccatcaaa
    25201 cgttcgacgt tgtttccttc tgtagcagag attggaatca cttgtgcaaa aggcatctgc
    25261 gttgaataat cttcgatgat tcccaacaac tcgtctggat ggattttgtc gattttattg
    25321 ataatcagat aaacaggaga atgcacgttt tttagacgtt caataataaa atcgtctccc
    25381 cgaccgcgtt tttgatcagc actaatcata aataagaccg cgtccacttc tttcaacgca
    25441 ctgtaagctg cttctaccat aaaatctcct aaacgatgct ttggtttatg gattcctggt
    25501 gtatcaataa aaatcaactg agcttctggt gtagtgtata ctccttggat tttatttcta
    25561 gttgtctgtg ccttgtcact catgatggca attttttgac ccacgattcg attcaataat
    25621 gtggatttcc ctacatttgg gcggccgacg attgcgacaa accctgattt atgttctggc
    25681 atatatgttc tcctttttaa ttaaacaaca aatgatatat tttagggaca aataaaatca
    25741 acccaacgat gacggtaaaa caagcggtca ctaaaactgc tccagctgcc atatctttga
    25801 tttttttccc aatcggatga aaatgaaaat ccgtaaacat gtccacgaca ttttcaaaaa
    25861 cagtattgat gatctctact atccatacga gaaaaacagc taaaagcagc cataaccatt
    25921 ctatccgatc aagttggaaa atcacgccca taaacaaagc gaggattccg aacgcaacat
    25981 gtttcctcat gttgcgttct tcctcaaaaa cagttttgac tccttggacg gcaaattcca
    26041 cggacatcag gaaatgtttg tttttctcta cgtttttatc ttttaagtcc ataggcatct
    26101 aagatctctt tctgtaaacc aaacatttct ttctcatcct ctggtgtcat atggtcatac
    26161 ccgttgatat gcaagaatcc atgaaccgct aaaaagccaa gttcccgatc atacgaatgg
    26221 ccgtaagctt ctgcttgctc tgcagcacgt tcagtagaga tcatgatgtc tcccagtaca
    26281 cgaggcaatg gattctctcc atcttcaaaa atcactggga tttcgtcttc gccctcttct
    26341 tccaaggcaa aactgatgac gtctgtcggt gcatcttttc cacggtaatc acgattgatt
    26401 acttggattg ctgcattgtc catgaaagta acagacattt ctgtttcttc tggcaactct
    26461 aaatatgatg ctgcaaattg cagcaagtcg tcgatttctt tcattttctc ttctgagact
    26521 tggtttgttt catccatgaa ggtaatatcc attatacatc gcttctttct attcttcttg
    26581 ctattcttct tgttcttctt ttatcttctc aacttccgat ttcattttag gatatttgat
    26641 ccgagaatgg aaggtactgc ttaaaccgct gatcaatgat ttttctactt tacggatttc
    26701 ttttaacgtc aatccactgt cgtccaattg tccatcggaa atacgctctt caataagatt
    26761 atggacaaaa ctttcgattt tttcgctcgt tggatggtcc attgcccgta ctgccgcttc
    26821 acaactgtca gctatattga cgattcctgc ttcacggctt tgaggttttg gtccaggata
    26881 acggaattgc tcttccgtaa cttccgggtt gcgttccttt gccttaacgt agaaataacg
    26941 catcagcgtg gttccatgat gctgtctaca aatatcgatc accatttgcg gcatattata
    27001 atcttccaat attttggcac catctgtcac atgtccaaag ataatatgtt tactgtcttc
    27061 tggcaataag aaattgtgcg gattttccgc tcctgaaggc aagttctcaa cgaaaaagct
    27121 ggcgtgtttg atcttgccga tatcatgata atagcaagct actcgagtta gtaaagaacg
    27181 tccaccgatt tctgctacag cattagcact tagattggct accatcatgc tatggtgata
    27241 cgtacctggt gcttcttcca gcaactgttt caataaagga tgattgggat tgctgagttc
    27301 atttaatacg atcacactat catcattgac catcaattca atataggggt gcagacctat
    27361 cgtcagcaag aatgaaaaca gtgcacctgt gaatccgcag actagcgtta accaagtcgt
    27421 tgcatcccca aagctcattc cttggtagat aatcaaaatg acatccatca tcacaggaaa
    27481 aataatgacc cacatagcag cggataaccc ttgttctgag atccgtttgc gtctgacgat
    27541 cgttgccatg agaccagaaa atacatagga catcaaaata actgtcagaa agttcgtgcc
    27601 aatcgaatca taaaaaatga aaagtgcgga tactgcttga aaaataccag ccatgatccc
    27661 tgctcttcga ttcaagaaaa agcttaaaac aagtggagca aaagccgcgg ggtaaaacag
    27721 cggaatataa gcagcttgtt ctgtttggaa gagttggaaa aatttcatta gtacgacgct
    27781 tactgacatt gccgtcacgt agaaaagtac gtattttgtt ctttctcctg cattttggaa
    27841 ttgaagtgaa ttataaatca gtacaccgat ttgaagcaaa acagctaaaa ccatggcaat
    27901 gagtgggaaa atagaagtcg tttgattcgt caatcctagt aattccaatt ttttcatcgc
    27961 tgaagcatca atttgatttc cttcgcgaac aataatttct ccttggaaga tcatcactgg
    28021 ttgtacagct tctcgtgcag attgttttaa ttcttctgtc tttttctcat tcaatacatc
    28081 attaactacg atgccttgat ccactaagta gcgaatcatt tgttgctgct ctgttgtgac
    28141 attcaaatat tgaatctgat cttctgcttc ttgtttaaaa gcttccaatt cgctttcacg
    28201 aacttgttta ctcatctgtt cgtcaatgag cttcaaactt tcatccctaa ctgtgtgaat
    28261 ttccgtttca gtcatttcaa atatcgtcga ataaaaattg ttcggcagtt tttggtaaaa
    28321 cgcaacgttt tctgcattca cgttttcaaa atttttcttc agtgtagcaa tccgctcttc
    28381 tgtagtaggt ttcgggatat tttcatcttc cttcgcctta tctaccttgc cattataaga
    28441 tttgttgatg gtatcattcg tcttatcgat caattcgaat aattgcttga tccgattgtt
    28501 ctggtcatct gccagatctt tttgataagt atattctgga gtcactgctt ctgctgccag
    28561 ttttcttctt tgttcggttt cttccgtgtt ctcaatcgtt ttattcgcac ggatactctc
    28621 ttctgctact tggccttctc tgaaatcaat ggccttttgt ttgacactac taaatgtaac
    28681 gccgcagaca atgataaaaa acaagaacag aaggaaaggc aatgctgcct ttccgagttt
    28741 ttcttgtagt ttctgcagtg ttttattcaa catgtgctta tcctcctaag caaagcttat
    28801 tcttgatgaa gatccgcctt ttcataagct ttgatgattt cggcaactac agggtgccga
    28861 acaacgtcac ttgcttcaaa attaacaaaa tcgatttttt tgatttgctt taatgttcgt
    28921 tctgcatgaa caagaccact tgtcgtccca cgaggcaagt ctatctgact tgtatcccca
    28981 ttgacaatca tttttgattg ataaccgaga cgggtcaaga acattttcat ctgagcgact
    29041 gtcgtgtttt gtgcttcgtc caagataacg aatgcatcat ccaatgtccg cccccgcatg
    29101 taagctaaag gtgcgatttc gatcacgcct cgttccatca atcggttcgt atgatccaat
    29161 ccaaaaattt ggtataaagc atcataaaca ggccgcagat aaggatccac tttttctttc
    29221 agatccccgg gtagaaagcc taggttttcc cctgcctcca cagcgggccg cgtcaaaatg
    29281 attttttgca cttcgccttt ttttagggca gcaattgcta atactacggc aagaaacgtt
    29341 ttccctgttc cggctggccc tacaccaaat acgatgtcat gtttggctac cgattcaacg
    29401 tatttctttt gaccgctgtt ttttacccgt ataggttttc cattacggtc tttgacgatc
    29461 tcttcctcat acatctcaac aaaataatct aatgtacctt tttgccccat tttcaatgcc
    29521 gtcacaacat ctggcgtact tacgtggatt cctcgtttga tcaattcctg taatgtccga
    29581 atgactgagg cagccaagga aatctgggat tgctcaccaa tgatctgaat gatttctcca
    29641 cgtgtatgga tggttgtttc cgttgtttcc tcgatcagtt ttatatgctt gtcgtgtgca
    29701 cctaaaagca tgctgacatc atcagcagct gtcaatctaa tctctaaaga actagactct
    29761 tccgtcaaaa atagacatcc cctttttttc gattcattct ttcctatttt accatactca
    29821 gaagaaacta tatagcaaat aagaaaaggt tgtaaaagag tcgcttaacc atacgtacca
    29881 agaaacgtta aaaaatagcc gtttccattc gctaaaggtc tcgttttgat aaaaagaagc
    29941 tgagaatgta agttatatga aagtggagaa caaaatattt cgtttcattc aacaagtatt
    30001 ctctaggtat ttttcctgtt tcaaaaaaag aaaacaaaat agttaaaata ttcttgcatt
    30061 tcaaaaaaaa caggtgtatt attacgtcaa caaataaaca tacagcaaag cgtcgaggaa
    30121 aacagtaggc tattcaacga tttattccca gtgagtcatg taagtgagaa atgacaataa
    30181 atcgaataga cgaacatcat ttccgagtca atgtcgaaaa cgtagatcat tgtggctgcc
    30241 tccattatca ggctagcgga taactttatc aaaaagcgtc cgtgaatgaa gaagcttttt
    30301 taagcgaaaa aaggtggtac cgttctagaa tctagagccc ttttcccaag tggaaaaggg
    30361 ctttttttta ttttaaggtg gtggttttca tggaatctga tattagtggc attactaatt
    30421 gctgcaacgt ttatatcgtc aatcaaaatg ataattattg gaggaaaaat ttatggaaga
    30481 aacaaaaact tattcatgga aacaactatt gatggtcagt tcacttatct tcgggatgtt
    30541 cttcgggtca ggtaatctaa tctttcctgt ccacttaggt caaatggctg gcgcaaactg
    30601 ggtcagtgct ggcgtaggat ttgctatctc aggtgctctt ttcccattac tagctatctt
    30661 agctgtagta gtgacaaaaa gtgatggtct gtatgactta gctaaacctg tcggaaaatg
    30721 gtatgctgcc ttgttcttaa tccttgttca tttgacgatc ggaccatttt tcggtacacc
    30781 acggacagct gctactgctt ttgaaatggc tgctaaacca tttttgcctg aaaaatataa
    30841 ttcattaggt atgtttttat tctctgctct tttcttttta cttgcttatt tccttactgt
    30901 ccatccaaca cggttggtca aatacgtcgg aaagtatcta aactccttgt ttcttgcatt
    30961 attagcaatc atttttgtcg tttctttatt ccatccaatg ggaaatctaa atcaatctgc
    31021 tgcagatact tatcaaacaa acgctttaac aaatggtgtc ctagaaggtt ataacacggt
    31081 tgatgcagta gctttgcttg ccttaagtgt cacttttgtc catgcagtcc gtgaccttgg
    31141 tttcaaagat aaaaaagtca cagaattaac ggcaaaagct ggtagcctga gcgttgcgct
    31201 agaagtcatg atctattttg gacttgttct tctcggtgcg atgagtttga ataagatgtc
    31261 tttatcagaa aatggcggaa ctgcactttc tcagatcact aatttttatt taggtaactt
    31321 cggcgctagc ttcttaggag tgatggtcac attaggtgtc ttcactaccg ctatgggact
    31381 cgttgtttct tttgcgcaag atttccataa actgttccct aaagtcagtt atatgacatg
    31441 gctgcggtta acgactttcg tctcttttgt cgttgcaaat gctggtttag acaatatcat
    31501 ccaatggtct ttaccagtat tgatgctttt gtatccattg tcgcttgcgt tgatcttgct
    31561 ttccttaaca gcaaaatttt tccaaaagac accatttgtc tatcaagtaa cgatgttgtt
    31621 tgctgctgtt cctgccgtat tggatatgct ggcaaattcg cctgctttag tgagtcaaca
    31681 aagagttgta gcaagcatgc tcgaatttta tcatcatcac gttccttttg ctgcattagg
    31741 acttggctgg atggtcccaa cgttacttgg ttacgctggc agcctactgt tttattacgc
    31801 ctatcgccta tcagggtata aacaagaagc aaatgaacta ccagaagaat aaccaaatca
    31861 aacacaattt aacataagaa atattaaaca ggaaaaaacc agctagatga aagaatccta
    31921 ttctttcgtc tagctatttt ttagttctct tttttacgcg cacaaaaaaa ctgcggacaa
    31981 tgattgtccg cagtttaaat gggctctata atatctagtg ttggtgacgc cttctgttgc
    32041 caatactttt tcttttttct aataaacgca aacagacacc ttgaaatcct ttagaataaa
    32101 gtcgacgaaa accattcaaa ggagtgtttc aagatgtcct attcagagtt taccaaagag
    32161 ttactagata ttctagacct aaatcttatc tttcatgaag atgcctttcg caaagagcga
    32221 atcaatgacg aaacatgttt tgtttttgat ggcacattga cctatcaacc agaggaatgc
    32281 ttccattgtc actatcaaaa taagcaaacg atcattaaat ggggctggaa aaaagtatcc
    32341 atcttattga atgatgtcag taactacaag accattctgc ggattaacaa acagcgcttc
    32401 aaatgtaaac actgtggaaa gactttttta gcagaagatt cagttagtga tcgtcgctgc
    32461 tccattgctc gcagagtcaa acaagccatt cttgagctat taagcgaacc tctttctatg
    32521 tctttgatcg cacgtatgaa gcacatttct ccgaccactg tcattcgaat acttcgcagc
    32581 cttcggccta aaaccgtttc tttgaaccag ccgttaccag aagtggtgtg tttcgatgaa
    32641 ttcaaatcgg tgaaaaacgt ctcgggagcc atgagctttg tcatgatgga cggcaagacc
    32701 catcaactga ttgatattgt ggaaaatcgg caactaaatc ctttacgcga ctatttcttg
    32761 cgctacccta gaaaagtccg tgaacaagta cgtctagtgg tttcagattt ctatacaccc
    32821 tatcgcacat tggtgaaaga gtgctttccg aatgcccgaa tcgtcgccga tcgctttcat
    32881 attagccaac acatcggtcg ggcctttacc aaccaccgaa ttcaagtaat gaagaccttt
    32941 aaaaaaaggg atcgtcggtc gaagcactta aagaaatact ggagactact tcaaaagaat
    33001 gcgtgggaat tgaaaggtca gcatcgctac tggcgtccgt catttcgaga tcatctgaca
    33061 gaagcagaga tagtcgatcg gctattatct tatgatgact ccttaaagcg aggctacgaa
    33121 gtctaccagg attttctttc cgctatcaga agacaagatg ttcctgaatt cgtcgcgctc
    33181 ctaaaagaag actacaagga gttgccagag cactaccaac cagtgttcac gaccttcaag
    33241 aaatatcgaa cagaaatcaa acgagcgttg cgagttccct attccaacgg ccctatagaa
    33301 tgtttgaaca accatatcaa agtactaaaa cgaattgcct atggctttag aaactttcaa
    33361 aactaccaag aacgaatctt tttatatcga ggaaaatatt ttaagaaaac taagaacact
    33421 acccaactga ctaaagctag aacaacaaca cggctagaca agatagctgt ctagccgtgt
    33481 gagtatctcg attattctat tgaattt
//
LOCUS       DAPBBR010000028        33094 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPBBR010000028 DAPBBR010000000
VERSION     DAPBBR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.028"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..188)
                     /locus_tag="RD488_001487"
     CDS             complement(<1..188)
                     /locus_tag="RD488_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657569.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
     gene            complement(335..670)
                     /locus_tag="RD488_001488"
                     /pseudo
     CDS             complement(335..670)
                     /locus_tag="RD488_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(682..2274)
                     /locus_tag="RD488_001489"
     CDS             complement(682..2274)
                     /locus_tag="RD488_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657570.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDQEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYVVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNSLTKVVKEPVRYD
                     RHAMNLLNEVYRNLPEKRSEWNYGDENRTKLSPYTREKLDELTQYVLTKEPEYQEYIQ
                     ISKALKEEAKNLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            complement(2294..2716)
                     /locus_tag="RD488_001490"
     CDS             complement(2294..2716)
                     /locus_tag="RD488_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657571.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
     gene            complement(2758..3033)
                     /locus_tag="RD488_001491"
     CDS             complement(2758..3033)
                     /locus_tag="RD488_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657572.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            complement(3817..4689)
                     /locus_tag="RD488_001492"
     CDS             complement(3817..4689)
                     /locus_tag="RD488_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657573.1"
                     /translation="MKSTDWIKHTWLPLKRNSKRKEFWILQLWPLGKLCSYLARFILD
                     LIIYSIVVFGTAYYLLNDPNRIAASDIFTVLMTLIFVMLLSIFTQIVMQFTRQKLTAG
                     KLFKSLFDLIIVNAILATLIKQIEQFGRTTKGVKEFLMTFVHFVNGHMYLFEVGIILF
                     LVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYYVDFGRYDELINTDIVHTSIHEATVKG
                     IRTTLKDGQETKAIDRRKEVYNFYEVEANLRYGIGKLSLNGRNIPQNKPYIGWKSDAL
                     EVTKKLPMEEEEIQ"
     gene            complement(4953..5183)
                     /locus_tag="RD488_001493"
     CDS             complement(4953..5183)
                     /locus_tag="RD488_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657574.1"
                     /translation="MKRANLVGKDTFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKFRSFEALYLAAKKYFTAERK"
     gene            complement(5206..6012)
                     /locus_tag="RD488_001494"
     CDS             complement(5206..6012)
                     /locus_tag="RD488_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657575.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEISTNAFVNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFAVKLSHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKENI"
     gene            complement(6023..6667)
                     /locus_tag="RD488_001495"
     CDS             complement(6023..6667)
                     /locus_tag="RD488_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657576.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNLVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            complement(6683..7888)
                     /locus_tag="RD488_001496"
     CDS             complement(6683..7888)
                     /locus_tag="RD488_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7657577.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKNSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            complement(7888..9912)
                     /locus_tag="RD488_001497"
     CDS             complement(7888..9912)
                     /locus_tag="RD488_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDT7657578.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKCFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            complement(10075..10668)
                     /locus_tag="RD488_001498"
     CDS             complement(10075..10668)
                     /locus_tag="RD488_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657579.1"
                     /translation="MRVKGQNSVDRKSILQFGKPEERSILDLFPYKSCTEEGVLITKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(10669..11001)
                     /locus_tag="RD488_001499"
     CDS             complement(10669..11001)
                     /locus_tag="RD488_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657580.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTIGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(11095..11565)
                     /locus_tag="RD488_001500"
                     /pseudo
     CDS             complement(11095..11565)
                     /locus_tag="RD488_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11626..13986)
                     /locus_tag="RD488_001501"
     CDS             complement(11626..13986)
                     /locus_tag="RD488_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657581.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQNV
                     FSWIYNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTTVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLNDIRKNGFGN
                     RKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEEKLDGTRAKELAEAVKNPSETLEKQKEKASEVKEGLKDAYGEGQVNA
                     AVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLPKTDPEQYRYKSNINS
                     ENEKRISDLPKRNQEVQTDDDSIDLPNDNGVEVGTEKSTKNGLPKAQNLPMKDSRLNQ
                     FKENDQSFVHQSTAGNVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAP
                     EPIQKVHTGYKPANVAFTAPTKINVTRDTKNRNNALKEQLLKDIKP"
     gene            complement(13983..16592)
                     /locus_tag="RD488_001502"
     CDS             complement(13983..16592)
                     /locus_tag="RD488_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDT7657582.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPDNEFKQLNALDEFMNQLPPGNTAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     INSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            complement(16592..18655)
                     /locus_tag="RD488_001503"
     CDS             complement(16592..18655)
                     /locus_tag="RD488_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657583.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGQLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            complement(18725..19027)
                     /locus_tag="RD488_001504"
     CDS             complement(18725..19027)
                     /locus_tag="RD488_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657584.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            complement(19045..19287)
                     /locus_tag="RD488_001505"
     CDS             complement(19045..19287)
                     /locus_tag="RD488_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HDT7657585.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            complement(19284..19748)
                     /locus_tag="RD488_001506"
     CDS             complement(19284..19748)
                     /locus_tag="RD488_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657586.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            complement(19775..21865)
                     /locus_tag="RD488_001507"
     CDS             complement(19775..21865)
                     /locus_tag="RD488_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7657587.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKTTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            complement(21862..22122)
                     /locus_tag="RD488_001508"
     CDS             complement(21862..22122)
                     /locus_tag="RD488_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657588.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            complement(22135..22896)
                     /locus_tag="RD488_001509"
     CDS             complement(22135..22896)
                     /locus_tag="RD488_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657589.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLFSDQLKLVSNGKTKTIDQQT
                     GVFEFSIEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            complement(22912..23664)
                     /locus_tag="RD488_001510"
     CDS             complement(22912..23664)
                     /locus_tag="RD488_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7657590.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIVAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWTWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            complement(23679..25655)
                     /locus_tag="RD488_001511"
     CDS             complement(23679..25655)
                     /locus_tag="RD488_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7657591.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGAGGITVNGVKSETSPYSVFKWGDIA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGIGIKATPLEGAEFAAKNAEGKYYGGLVDTDKNGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            complement(25708..26382)
                     /locus_tag="RD488_001512"
     CDS             complement(25708..26382)
                     /locus_tag="RD488_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7657592.1"
                     /translation="MDEKMVIFFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKIPV
                     DQINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIF
                     KGTNQYTLSLGAATYFYEDGEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSN
                     DGVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYV
                     VQGELQ"
     gene            complement(26459..27621)
                     /locus_tag="RD488_001513"
                     /pseudo
     CDS             complement(26459..27621)
                     /locus_tag="RD488_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            complement(27627..28316)
                     /locus_tag="RD488_001514"
     CDS             complement(27627..28316)
                     /locus_tag="RD488_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HDT7657593.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGHQKDKIAEKVDGVTK
                     TIHIQEQDKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYPDAEMGNGNYILAGYNVDTPSVLLSDMIDLSEGEEIDLIDA
                     HYKYQYEVSKRGKIYDYSQVVQSKENNSFLSLPKAGKKPLLTLLDFEANNMKKCDVIQ
                     CELVNVEKINK"
     gene            complement(28443..28637)
                     /locus_tag="RD488_001515"
     CDS             complement(28443..28637)
                     /locus_tag="RD488_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657594.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYISDMQITGKEKACLLGSMKNFE
                     QLRRTYVKIRSNCQLLLEVS"
     gene            complement(28747..28986)
                     /locus_tag="RD488_001516"
     CDS             complement(28747..28986)
                     /locus_tag="RD488_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657595.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARSYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWRIYNGIKDLKPARPVVKRKKKITQE"
     gene            complement(29153..29494)
                     /locus_tag="RD488_001517"
                     /pseudo
     CDS             complement(29153..29494)
                     /locus_tag="RD488_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
     gene            complement(30113..30445)
                     /locus_tag="RD488_001518"
     CDS             complement(30113..30445)
                     /locus_tag="RD488_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDT7657596.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(31270..32310)
                     /locus_tag="RD488_001519"
     CDS             complement(31270..32310)
                     /locus_tag="RD488_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7657597.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
BASE COUNT         9310 a         6573 c         5015 g        12196 t
ORIGIN      
        1 aatggataat cttctgccgc atcgacgaac gtcttcgtag tcagatttaa cgttaaaata
       61 tcgccacttt gataagcttt tgcagctttg tctgtgacta caaaagctct gcctgtttga
      121 atttctgtca caaaaacgag attgtctctg cttttttcaa caacaactcc aatagttgaa
      181 taagccattt ctgcttcctc ccttctcttt cttttgatat aatgtagtcg gaaatcgcac
      241 cactcaatga attggcggaa aacaattcag tgaaaaaaaa gagtcctgga caatcacgtt
      301 caggactctt ttacttcttt tattcactta ataactaaca ctctgtgagt gaaatagact
      361 cttttatgct tttacatgga aagttattga ttccctcttc attcatttcc caagtagtat
      421 aataaggtgt taacttggcc tcatattctt gaatgataaa atatttttca ccgttcacat
      481 gattacaaca atacacacca gtagctgggt actcaacgac taaaaattaa tttggatcaa
      541 tctgttcgct tctcaacatt tctcttatct gaaacaaatg ctctttttcc aaacaatcgg
      601 gaagttgttc gattcgttct ttttttagtg atccttctat gactttccat tgattcaaat
      661 atcgtttcat ttctcttcct cctactgtct ttcttgttcc atttgaattc ttcgttgttg
      721 ctcttcgtat gctttacttg cgtggtattt ttcttcatgg gcattaatcg ttcgatttaa
      781 ttgacgcaaa ctccgctgcg tgacaactct ttgttggaat tgtttcctgc gcttcatgaa
      841 ttcttcgtaa ctatatttgt attcattcgt tggcaattgt ttaagcgttc gaaaggatcg
      901 ttcattgtaa atagattgca tctgatcaac actttctatt aatggtttta tttgactatc
      961 ctgtctcttc agctctgtta ggatggcatt tcctgtgcgc ttttttaaat caaagagagc
     1021 atttttctct gcatcctttg attctctctt gctttcccca taaagatttt ttgcttcttc
     1081 tttcaatgct tttgaaatct gtatatattc ttggtattca ggttcttttg ttaacacata
     1141 ttgggttaac tcgtcgagtt tctctcttgt gtatggtgaa agtttggttc gattttcatc
     1201 cccataattc cattccgaac gtttttcagg taagtttcta tatacttcat ttaataagtt
     1261 cattgcgtgt cgatcataac gtactggctc ttttaccact tttgttaagc tgttacgcaa
     1321 atcacttttt cgtgtcaata aatttcgttt ctccatacca atcattcgat ccttttcata
     1381 agagaaacgt tctaactcat gcacataatt ggttttcatt gcgtctaatg ttgcttgcct
     1441 tctctttcct ttcggtacaa cataactcac accattttca acctcagtgt aaggtttacg
     1501 cgtattttct ttttcaacaa ctgcaaaatg aatatggata tgtttagtgt tacggtgaat
     1561 cgttgccatc cagtagcctg tttcgttcag ttgctctttc tcgaataatg tctccatcat
     1621 ttttcttcca gctgctttta acccttcttc atctaaagta tctgttttgg gatcgtacaa
     1681 tcctattttt tcaagatacg aattatcatg agagacaaca tcttgataaa tgattgagcc
     1741 tttttgttgt cctctttgga agatttgctt aatctccttc agatcacttc ctttcacttc
     1801 gtctgaagcc atagaaaaaa ctccaggaag gtttcctgaa gcttttttgt gtggctctgt
     1861 ttgatatttt tttattgctt ggttcaagcg ttggtattct ttttgttccc tttgcgtcag
     1921 ttctttcttt tgttctaacg catagtgacg ggtcatataa gaaagatatt tggtaaaatc
     1981 ttgttcctct aacttgtcaa agttgattcc atttcccatc aaagattgag cttcattcga
     2041 cgtttcgctg aattcttgat ccgtcttact ctccgaaaaa gtttctcctt caggaatata
     2101 aaaatcctct aaagcattct tgattcgttg cagttcctgt tcttcttcag gcgtacgtcg
     2161 ttccatttct tccagcgctt tttctcttgt catataatca atgtatgttg aaaaagattt
     2221 tttattgggc aaggtaaatt gacaagtgag aatgactgca ggcgatttat tcatcatgtt
     2281 ccccttctac tttttatctt tttaaaaact ttgttggatc aaacgggtct actctggcat
     2341 gaacagattc atttattgat ttcttgattt taggagaata cttcttcgtt tgattcgctt
     2401 ttattttccc ttccacacgc tcttttgctt cttggtaaac agttgaattt gtaccaatta
     2461 aaatccctgt atctttcaaa tgaagatccg caaactctga aaccatctcg gttaaaatag
     2521 aaatttcttt tcccattgca ttcaatttaa tttgaattgg atttattttt tcttcgattt
     2581 ttggatcata catcatacac aaatgtctga ctgcttcact ataattagat atatcttcat
     2641 gagtagaaat tatttcatca agtacttcga tatgcatatc gtaaagatat acatgttttc
     2701 ttgttgcttt tgccaaaatt gatttcctcc ttttataaat tcacaatact atttttatta
     2761 ttcaattaac aaaccaatta attgattatt tgttgcaata tattcttcta aagtttttgt
     2821 attataagtt tgaatatcca caaatttttc taacaaccga tcaaattggt cttttttata
     2881 attcagaaga gcgtgatcaa aatcattttc gatcaaaact tttaggtatt gatttcgact
     2941 ccattttttg ccagtcttga ccgtaagttc ttcacaacgt ttgtcaattt tattaatgta
     3001 cttttcttca atatttctaa ttaataagtc catattttcc tccaaattta ttatgtgtag
     3061 ggatatgtgt agctacacat atccctacac attttttgat tttgctacac acaaacgctt
     3121 attttactgc ccacattcgc tttcatccta cccacattcg ctttcatcct acccacaaat
     3181 ctacacacaa atccaaaatt ttgatatcat ttatctttct tagaaacgtg gtaggcacag
     3241 cctacctagc acctttcgta agaaagtgat atcacgtttc cttatgctct ttaaaaatta
     3301 aggttatttg tgtatttaga caataaaaaa tccttctaac tttgtcgatt agaaggaaat
     3361 attttgtcat atgaaaaatg aatttaagaa aaagtgtatg ctataattga tacgctgtct
     3421 tcctgtttgg ttgaaatctt cagccagaaa ggaggagtgt taaatgtttt atgtgcttga
     3481 tgtttgcgtt agaatcgtgg ttaatgtttt ctcccatctc attaacaaat ggttagattc
     3541 taaacatgat aaagacagct agcctgttca ttatttggtt aatagtgaat aaagaaaaga
     3601 gccttacgca gctgcaactg ctagggctct ttttgagtat taaatgtttt atgtgtttgc
     3661 attatcagta tagcatacac ttttttcaca gacaactttc tacatttttt cttctttttt
     3721 caatcaaaat aaactaatga ataatataaa ctcttattga gaactgttgg aaatgattac
     3781 tgatatcttc aaacaaatga ttcaaattga ctagactcat tgaatctcct cttcttccat
     3841 aggaagcttt ttagttactt ctaaagcatc acttttccag ccaatgtatg gtttgttttg
     3901 tggaatattt cttccattta acgacaattt tccaatgcca tatcttagat ttgcttcgac
     3961 ttcataaaaa ttgtagacct cttttcttcg gtcgattgct ttcgtctcct ggccatcttt
     4021 taacgtagtt ctgatgccct taacggtagc ttcatggata ctcgtgtgaa caatatctgt
     4081 attgatcaat tcgtcatatc ttccaaaatc aacatagtac tcataaccaa gaagtgtcgg
     4141 aatcaagtca atctcaattt ctttttcaat tgaacgttta ataagtttcg tggatacata
     4201 cccgactaaa aagagaataa tacccacttc aaacaaatac atgtgcccat ttacaaagtg
     4261 aacaaacgtc attaaaaatt ccttcactcc ttttgttgtt cttccaaatt gttcgatttg
     4321 ttttattaaa gttgctagaa ttgcatttac aataattaaa tcgaatagac ttttgaaaag
     4381 ttttcctgct gttaattttt gcctggtaaa ttgcatgact atttgagtaa aaatagacaa
     4441 tagcatgaca aaaatcaacg tcattagcac tgtaaaaatg tctgatgctg caatcctatt
     4501 gggatcattt aataagtaat aagccgttcc aaatactaca atcgagtaaa tgattaaatc
     4561 aagtataaaa cgagccaaat agctacaaag tttacctaat ggccataatt gtagaatcca
     4621 aaattcttta cgtttgctat ttcttttcaa aggaagccaa gtgtgtttga tccagtcggt
     4681 cgattttatt tcaatttctt ctctcatttc tttcttcttt tcttgccaac gagaaggcag
     4741 aagtttgttg atttctgtcc ccaacaaaat caataggacg catgagatta cactcatgag
     4801 tcccttcaat aataaatctt cattagtaaa ccatagaaaa atcgttccca aggtcacggc
     4861 tacaataaaa aagaagccaa cgatacctac ggtgatatag ctgatccata aacatttttg
     4921 atacactttt ttcacataaa atcctcctgt ttttattttc tttcagccgt aaaatatttt
     4981 ttagcagcta aatacaaagc ttcaaatgat ctgaatttta aggtatctaa actctttcta
     5041 ccattcttca actcagatat tgttgtgtta gataaattca cttcttgaca tatttcttta
     5101 gcttttacaa ctttgagata ggctttaatc aatactttct gctcagcgaa agtatctttg
     5161 ccgaccaagt tcgctcgctt catttctttt actccaccta ttcttctaaa tattttcttt
     5221 tgtcatacga tcaatttttt cttgaagttt ttgaatgatc tcttcttgat ctttcatttg
     5281 cgttttcgat gtttcaattt cttgctggta actattaatc ttattttcag tattttcctg
     5341 atcgtctgca acttgataag gcaattgatc ttttagtttc ttcactaatt cttcattcaa
     5401 atcaatggtt gcttggaagg attcaatctg tttttgtgct gctttttgtt cttttttgta
     5461 tcctttcact ttgtaattga tcgcatgttg ttcataatct tcatctttca cttgatcttt
     5521 aaccttatct tcgtgaacgt aataaatcag atcttgcggt tcttgcatat ccacttttgg
     5581 atcaattttt tcaggaataa tggttaaacg catggcaata tattcttctg gtacatgaga
     5641 tagcttcact gcaaaataat catcagacac tttgatcact ttggctttta ttgcttgata
     5701 atccccttta gctgtcttta cttctacgcg ataattaaga ttagccagtt cttttaataa
     5761 gctttgatct tcatcgtcga ttgcaaattc aaaaactaat tgctggttcg ctcctttttc
     5821 ttttgaaacc atcgtcagtt ccttcgtgtt tacaaatgcg ttcgtgctta tctcatctgg
     5881 tatgtctacc ttcttatgcg tataaattgg actagcaaga atcaaaaagc cgagaatcat
     5941 aaagatcccc agccatctaa gataactttt tcgttttttg aaacgttgtc ttgctccttt
     6001 tttcttactc attttcttcc tcctaacgag tgaaataact aaagtctgtg actttccatt
     6061 gaccatctac ttgtttttca gtgacagtta atccaccttt tattttttgc ggtttgacat
     6121 ctttgaattg aggattgccg attgtataat caacaaatac gacaagattt tgttcctctt
     6181 ttacactgct tgtttgagcg taagtttgca cgtcacctaa tgtaaaggag taacttccgt
     6241 aatcatcatg ttggtgatca tcgtctgcag gacttaattt gtcgatcact tcttgggttg
     6301 cgacatcttt tagtttttcc gttaattcat ttctgcttaa tgatttatca atggccaatt
     6361 gaccgaactc ttctgccgtc tttctttgtg cttcagttac ttcctctttt gcttttgtgc
     6421 catcttgttg cttcagctga tcgatttctt ggtttttctc attgatggtt tgatttaact
     6481 tgtcgatctt cgcctgtgcc tcagaggaat tttttttgag cttctcagac gcgtttttag
     6541 ccacttcttc aattttaaag gtatttgtct cttgttcttc tttcagctgc caaaacaacg
     6601 cgatattgcc gattaaacta acgctaattg cagctgttaa gacgattttt aaagttttat
     6661 tttccatatt ttttctcctg atctattttt tgctgctatt caaaaatggt aatggatcaa
     6721 tccatgtacc atcgtctgtg aatgcgtgtc cttgtgcttg acgccaatcc attcgagtga
     6781 aacctaaatg caagtgtgct gtatctcgta tcccgattac ttgaccaact ttcacttgat
     6841 cgccaacctt cacacgagaa tttcctgtac tattcgcaaa ttcttgatat accatattca
     6901 aaccgtcgta attaatcacg atcacacatg cacctaaacc tgaaatacca ggattgccaa
     6961 cgtacacgac ttttcctcca tgcaccgcgt gaatttcact tcctggatga tcgactgaac
     7021 caaagtctaa tccatcatgg aagccattcg gacggaattc accgcctgga tttgttccaa
     7081 ataattgacc accactgaag gaatttttat ctaaactgct gccagggaat ggattcgtcc
     7141 attcaccagt gatcgtgccg ttgttattgc caccttcacc ccaatgtttg atggcgaatt
     7201 catcatattc ggttaattta ttagaagtga taatggacat acatcctgta taatacggac
     7261 tatcttccgt aattcctgca gcggcataac cgcctcgtcc taagatcaat aaacttgcgc
     7321 cagggctttt atttcctaca catgcattaa aattggattg tgtggctacc ataaagccgt
     7381 aatatgagaa ggcagctttt gagttgggaa acttcatgta ccagccacct tcaatgccac
     7441 caattcctcg tgcagttcct ttaggaaaca gacaaccatc aaaccaagta atcccaaaat
     7501 agttgagatc atttcttgcg gacgccgacg taccaaacgc tgattcataa ccgtattgcg
     7561 aaaggatcac acttggtaat aatttatatt tcactgctgc acctacagca tattgcgcaa
     7621 tctcatcaga aaaagggcct cttcctttga tttctttata aatcggtaag ccttccgaat
     7681 attctcctgt aaaagcttcg ccaccactac ttgaatctga atcagaatta tcaatcgaac
     7741 ccgccgcaag tattagaaaa agggtcacga acacagtaat caaaatagta atcaaacctg
     7801 cagaagtacc aaacaaccac aaaaataagc gtcgctttgc acgacgctta acatactgct
     7861 tgattaaact ttcattttgg ttttccatta ttttcctcca tcaaacaatt ttaattgacg
     7921 tttgttcgga ctaaaatgaa cacgaatggt ttcttttgag ccaaaattga tcacagcgtc
     7981 tccttgattt tgttgaggaa tggattctaa ttctgagttt gtcattgatt taccaactaa
     8041 tccttctata tgacgtaaaa tagattcatc catacgcata aagatcttcg tagaagaaaa
     8101 ttcaaagact ttcttcagtt tcgagaagtt atcagaagac atattttctg gcaccatttc
     8161 ttgtggggat tgtgtagcta aaacagtcat tgcttctact ttacgcattt ctcgttgaaa
     8221 gtttgtgaca taatttaccg tttcaataaa atctggatta atcgcattat ggcactcatc
     8281 aatcatcgcc aagaagcatt tgaagtcttg ttcttccatt tgtttttctt taattaaacg
     8341 tcgttgtctt cttccttgaa tcaatgcctg attccaaatc aacgtcatag ccatgtacat
     8401 ttgacattgt tgtaccccac gatctaaacc tgtaatagag tcaatgtcaa aaaagaccaa
     8461 ctgttgttgg tcaaggtgtc gaatcgtact atgaccatca aaaatcatgc catacgtctc
     8521 acataaggat tctacgatgg attccatttc ttcttttcga ttctttttct cttgggaagc
     8581 acctggtaat tccagttgtc ctaaaaagtc taaaaattct ttgaacgtcg gataagcttc
     8641 tggatctttc cctgtgactt gcgtctccgt atttgaacgc gagtttgagg aagtgaaacc
     8701 gcgtggtact gttccatact cttcataaaa acgatttaaa taggtcttaa attctgcttt
     8761 catcgttcct tttagctgag gactcactaa ctgtacctga tagaccactt tgtctaagtg
     8821 cgtttgatag gacgctgctt cattgatctt caaatctttg actgatccat cgtcatataa
     8881 actggaagct tcatcatacg tacgtgtggc aaatatttct aaaggattga tcatcccgtc
     8941 agatccgtct aaacgcacca taatgccgtt atattccttt aaaaagggaa taaagtcttt
     9001 tcccttttca aagccccaaa taaagtctcc tgcagctaaa tgggcttccg cgatcatttt
     9061 aagaacggtc gatttaccag ctcccatcat tcctagaagc aaggtattgg tagacaaccg
     9121 cacactattt ttatacgtgg cattccaaac aaacgggccg cctgtcatgg tttccccata
     9181 ttgtgttcca cctggatctt ttagcgtttg gtggtggaac gggaaacctc cgccaatgtt
     9241 tagcgatggt agtgattgcc ctttgatatt tccaaaccat tcagcttgtt catcgaacat
     9301 ggtgaacatc gattgccagt ctcttttcgt tttgtgcaga taggtcactg cacgataatc
     9361 catccctttg agattttcga tcagttcctg tgctcgttca tctacttctt gaatcgtgtt
     9421 tccgtaaaca tgtactctca ctttgacttg tttagaaatt tccccattag aagtcaattt
     9481 tcgggcatat tccgctagtt ctaggtattc ttccgcgctt ttatttcggt cagtcgcttt
     9541 tcgttcatta tctgaccgat catttaattc atctaaggca cgattgattt gatcaatcac
     9601 tttttgcttt tcatctgtgc taacatctag tgttgccact gtatgaggat tgttcatgag
     9661 attggccaac caaaaaagcg taggattttt tgtgtagtga taaactgtca cacatcgtga
     9721 ataaccattt ccataggtca catactcttc atcgaaattt aatccacctt gtggcatcac
     9781 ttgttttaaa aagtctaaat catacccttt ggattttaaa atttctattt cccgatttcc
     9841 tagttgcttt aatggatcaa gtaccttttg atcattttgt ggtgaaaaag ctgttttaat
     9901 tgcttctaac atgtacagtc acctcttctt gtttgattct ttacttggtt aaaagatttt
     9961 ccttttccca acttacccag gcttaaagtg tgaggaaatt ttctagtggt ctcttctttc
    10021 ggaacatctt tttctaacca tatcaacgga tatttcattc tctcttcccc attcctactc
    10081 atcattcata ttattcattc gataaagaat cttgatcaat tcttttttgt agagtggttt
    10141 taaccctaaa atgccactag atcgcattaa ctgacggttt ctggtttgca aatccttgat
    10201 tgtctttcct tcaatgacga aaaagaagct taaatcaggg cgttcctgtt ctgctcgttt
    10261 caattcctgg atttcctcta ctaatttctt ttcatatttt cttaatcgct gtagatttct
    10321 tcctaaggac tgttccatac gatttttatc taataactgc cgcttttgca cgatttgctc
    10381 cgttagatcc gtttctgtgg tcaaactaac taacttaatc gttggcacat acgtacgcat
    10441 gacagtggtc aactgattca ttcgttccag tttctcttgt tcatttaatc cttccacatc
    10501 tgtagaaact acacgataat aacgttgaaa atgatcttct ttagtaatta agactccctc
    10561 ttctgtacag gatttataag gaaataagtc caagatagag cgctcttctg gttttccaaa
    10621 ctgcaaaatg gattttctgt caactgaatt ttgacctttg actcgcattt attcatcctc
    10681 cttatacgta ccatgataat ttcggttagg atctaacgca tgataatggt tcttgtccgt
    10741 aaaaaaaata gactcgataa tcgcaaaaat ctggcgttga cctgggttat tatagggtcg
    10801 ccaaacaatc actaaagcta tcgcaatcca taagccataa ttcaagagtg caaaaaagag
    10861 tggtaagtgg acaagattat tgactatttt cgcccaaaaa aagcaaccac caatcgttaa
    10921 tagatctaaa aagaaaaagg cgaaaaactt ccattcccca ctaaatcttg gtggattttt
    10981 catatgaatg tatttatcca taatgtaacc atactcctta tgttctttat ttttagaaac
    11041 aaaaaacact gtgatttctc acagcgtttt tctaaatatt ataactctaa ttcaattttc
    11101 ttcttttaat tcaaaaattt tttgttctag gtttcttttc atttgaatca actcataatt
    11161 ttgtgcgcgt aattcttcgt tttccaaatg aactcgttgc atttcatcgt ttaatcgatt
    11221 taaattctcc aatgattctt gtatcgtttc ttgcctaaaa ttaagtgagc caagttgacg
    11281 atctttttgt tgtctttgct ctttcaattc tgacgatatt tgctcaacag aatgaaatag
    11341 ctccgttaat tttactgtga atgtgggcat agcatctttc aaataagtga atccttctga
    11401 aaggtgtaca ataatgcttt cggtatgtgt tttttgacca tctaaaatag actgatgatc
    11461 tttttgtaaa ctctccgtat ctttaaatcc tttaatagtc gccacaaata tcgttaaaaa
    11521 tgctcccagt gcagttataa acgtagctat taaaatatcc tccacaattt tctcctttcc
    11581 attttaaact tgttttataa agaaaaaggc ccttaaatag gccttttatg gtttgatatc
    11641 cttcaatagt tgttctttca atgcattgtt cctgtttttg gtatctcttg tcacatttat
    11701 ttttgtcggt gcagtaaatg ccacatttgc tggtttgtaa cctgtgtgaa ctttttgaat
    11761 aggttctggt gcagcttctc ttgtcacaac attttgaacg gacgcattcc ctgtctcccc
    11821 actttcagat aaattgtaag aaacagttgt cagatttcca ttttcaggca aacgacttgg
    11881 tttcatttga acattacctg cagttgattg gtgaacaaag ctttgatcat tctccttgaa
    11941 ttgattcaaa cgactatctt tcattggtaa attttgtgcc ttaggtaaac catttttcgt
    12001 tgatttttca gttccaactt cgaccccatt atcatttggc agatcgatgg aatcatcatc
    12061 cgtttgtact tcttgatttc gttttggtaa atctgaaatg cgcttttcat tttcagaatt
    12121 aatgttagat ttataacgat attgttctgg atctgttttt ggtaattgac cattttgtcc
    12181 ttcttctgaa ttttcgttag aatgcaactc atcttggtga tctttggctg aaggaatcgc
    12241 tgcaccttct tgattttctt tttcggttgt tgtattagct tttactgctg cattgacttg
    12301 tccttcacca tacgcatctt ttagtccttc tttgacttct gaagcttttt ctttttgttt
    12361 ttctagtgtt tcggatggat tcttcacagc ttcagccaat tctttagctc tcgtgccgtc
    12421 taatttctct tctaaggtgt ctttggcttt ttctgtaaga tcttcagctg ttccttttaa
    12481 cccacgttca ttgacgtaac caagaccttc tgcggcttta gaaacaccat ttttcgcttt
    12541 cccgaacatt tcggaaactg ttttcttact attaggtaca gttgtagctt tatcgtctga
    12601 ttgttcttcc ccgttatcag gggtaacatc ttttcgatta ccaaatccat ttttacgaat
    12661 atcatttaaa ttgcttaaac cactcttacc agcacttgca aggtttttag ccccgctacc
    12721 cacatttttc gcaatatttc ctaaggcaaa catgctaaga agagaattgc tgccgttttt
    12781 cagactcgta tcaacgccga aaattttcgt aactgattga gagcctttga atagcgcaat
    12841 ggttaataca attaaagcga caacatacaa gaatccattg atctttcctg ccgcatgcaa
    12901 atcaccgata cctgaaagca ttaatgtata gattcgtaat tctaaaatcg taaatgccaa
    12961 taacaagaag gattgagaaa tatcttctat agcacttttc atccgttgtc ctgtctcaaa
    13021 gtccgttgac gcggcaatca ctaaatagaa ttttttaaat accagctcaa taatgcaagt
    13081 aacagtcgta aacaagataa ataaataggc taccgacaaa gaagattcac cagctaaaat
    13141 aatacctgga ctactaatgt atcggcgata gcctgaagta tacacatatt ttgctaaacc
    13201 ttcatcacta atttgaacag ggatttcttt cccattatcg tctaactcta gtcgatactg
    13261 taatgccttt aaccgatctt tttgtactgt actaatatca cttgattcag acattttctt
    13321 agcttgatca ggtgtaataa tcccattgat attcgctgtt ttaaaatttt tcgccgtgag
    13381 agcatttctt ttgtctgttg gtatgtgttc tactttgttc ggatcatttt ctagtaacgt
    13441 actcacatca atcacattat tttgaataat ttgaaaagca ggtgaaccag ttttatctgc
    13501 tttatttgct gcagtcacgt ctccgtaaaa gtttttacta atatttagcc cttcatcgat
    13561 taaagaacta ccaccaaaaa tcaaaatcat ggccataaat agattaacca agatattttt
    13621 gatttttggt ggatgtttac tcataaaaaa ttttaagcct aaataaatta atgtgacgac
    13681 acaaaaaaga gccaatacct tactaatcaa actttgaaac agttcattaa caccagcggc
    13741 gttcaataag tcttttaaat caaagctttg ataaattgtt ttttctagta aagtattgag
    13801 attatataac cctttaatca aaccccataa aaaagtatta taaatccaac tgaatacatt
    13861 ttgatactgc agataattac cataatcttg taagactttc gttacggttt tgggatctgc
    13921 atccccatcc ccaaataagc ctgaccacca gtcggcaatg ccggaaaata ttcctccaat
    13981 gatcattctt tcaccgcctt ttcagcttct agcaaaagtc gtttccttat aacctctgta
    14041 atttcttcat tttgacgcaa tttttcaagg tattcttgca aacgatctat ttgcttctct
    14101 tcataaaatt gaataagtaa cttttgtgcc gttgagttgt ctaaagattg aacgatttta
    14161 ataaaaatgt tttctttagc ttcctcttct atttgatcgt gcatattgtg ataaagtcga
    14221 cgtgcataga tatcaggtag aaaataatcg taatcaattt gtaaagcctt aagatccaag
    14281 tccgcatgtg tacaatgtat gtctatatca ttgatatccc acgatggatt gaaatcttca
    14341 atatattgat aagcataagg aagattcgtt tccccatgat taaaaatagg atacggccgt
    14401 attttatgac ctttcaaatc ttgtcgtttt aaaggagcga gtacaatcgt ttcaccttct
    14461 aaaaaagtag aaattctttc aggagttaag atgcgatctg aatcaacatt gcgattgata
    14521 tgagtattca tacctaatga attgatggta ctgttctctt gttcaaccgt cttattcccc
    14581 acttttttgg aaaattcttc tatggtatta tcgtctgtcg acataatata aatatgtgtc
    14641 tgacaatttt ctttgataat cgctgcgttt tgttccccat acttcgcata aagttgctga
    14701 taggattgga taaacaaatc ccacaacatg tttctaccag ctgtgactgt catgattcct
    14761 tccatattat ccattggtgg catattccca aattcatcta aaataaaatg aatcctacgg
    14821 tgacatttat ctcctttagt cttaacacat tgcgtagata attctttata caactgacta
    14881 agaaaaatac taacaatgat atggttagat ggatcataat caggtgtgag cataaaaata
    14941 gccattggtt tatcggtata gtgcatccga atagactcta ctaataagtt acttttatcc
    15001 tcatctaatg ttagaacggc ttctttttct aattctggca aatgggtttc tcctcgtttt
    15061 tttcgataaa cgatatttcc ctcttcgtct ttcaatactc tttgagaaaa ctcataccaa
    15121 gcaacatatt cttttcctcg atgatcgtat tttaagcaaa catgatctcc ctgttctaaa
    15181 tgacaatcaa agttaatttc acaaaaacct ctatagccta ctttgacacg ttcctcatga
    15241 aatttttttc cttgatgata aaactctaca acaattcgct ggtttaacag actctcgtgt
    15301 agtttgagat ccaaatactt cggaaaacca atggacttat aatcaatggt tgattgagaa
    15361 gtcattttcg caattttcgt cagtgtaaat ggatttagtc ctgtgatcgc tgtcgataga
    15421 atgttgcctt tcgctttatc agaaccaatt tttgttgccc catattgttt ttttgctgtg
    15481 tttccaggtg gtaactgatt cataaattca tctaaagcat tgagctgctt gaattcatta
    15541 tcaggatctt ggtaattaaa accaccaatc tcagaaagaa gttcgacgag attattcggt
    15601 gttaatttgg agtaatcccc tgtctgatcc gcttgttcca ataacgcaaa aataagcgca
    15661 ttgacagctt tttgcgcatt ttcgttaaag tatttattgt ctgaagcgtt ggcatcataa
    15721 taaatcgtat tcgtgaaagt attggttaac tgtgtcgctg tgtctatgtc tcctcgcttc
    15781 cagtatttca cgatgagtgc caatggatta tcactcattg attgcagtgg atcggtgata
    15841 ttaaatgcat acacatcata ccctctagct tctagttcat ctttactagc aacatataat
    15901 tctgtttttg gatcattaac aaccattgaa ctttgtcttt ctgcacgaga caaattgtca
    15961 atggttgcta aaacttctat ctgtcctttc cctgaacggg aagtaccaac aatacaagta
    16021 tttactgtat ccgtctgaat ataccagtac tttttataat gagtaattgg tattccgcca
    16081 taaccaggaa aacctccctt tgattctggt atttgcggat aaatttgttg gatttccttt
    16141 aacgttttta atcggttatc tcctttttgc ccatctgcta gaggacgaaa ccacatgtcc
    16201 attttcaatc ccataagtac agctggaaca acacaaatcg tagaaacaac taaacgtgtg
    16261 cctaaacttg ttgttggggt caaaggattc caaaaaccag ttgaatcaaa atggaataac
    16321 tgcggcattt cttgtaactg aaaaatattc actccttgta aacttcctgg aataatctca
    16381 aatcgatgaa atgcttctgg tattcttgta acaacatagt ttaaaggaag ataagctaag
    16441 ccactataaa aaatcttttg agaaatacgt ttgtcatgtt tttctggtag ctcttctcct
    16501 gaaggagtat agcgatagaa atgagaaaga tacctattct tttctaaatt gaatcgtttg
    16561 tcttttcgtc tcgttgtttc tctaacacgc attatttcac ctcatttgat tctgaacttt
    16621 cggaagtgtt tgattgtaca gttgaatcgc ttgatccttc tttagcctta ctaggatcac
    16681 tctctttgct attttccata cttgattctg ttgttgactg attggtacga ttcaataatt
    16741 cttctaattg ttgttcatac tcttttcttg cttgttcttg ggcttcttcc ttgattgacg
    16801 tcgttgtggc cacagaatca gcctgtgaag attgattgat atgattaaaa gcaaatactg
    16861 ttcctccacc tagaagcaag cttaaacttg caatacatcc caccatccat ccgttaaagg
    16921 aacgctgtgg tgaaggagtt agatttgttt ggttgttcat tggggtttga acagcagcta
    16981 ctgaaggcgt tggttgaggt tgtgctagat aatttaactg agcttgtcgc aatgtatcca
    17041 tttgttcttg acgttcctta cgagcagctg cttctttttc cttttcttgg tttaaccgtt
    17101 gtttttctat tgccatttgt tgttccgcaa gatcctgttc acgttttttt agttctaatt
    17161 gttcgcgctc tttttctttt tgccgttgtt tttcttcttg ttctttcaat tcttgttgtt
    17221 gaatttcata ctcttttttc cattttggaa tttgcacttg taattcttgc tggatctttt
    17281 cgtgtttttc cataagaact tcagtcgttg tttgatatag cttattcagt tgttcattta
    17341 attctttgct aatctttagc ttatctgtac gcaaacctcg gtaaaattct tcttttcgtt
    17401 ctttaatacg ttcttttaac aagttttctt tttctttcga taacgcttct tgattcgtct
    17461 gagtaaaatt attgatcttt gctacacaca aggaatacgc attgtcgcgt ttcttttcgt
    17521 atcgctcttt aattttttgt acttcttctt caatcactcg ctgttcttct ttatttagtt
    17581 cctcttttgc tttctcccaa ttagacgact gttccgtcgc atactcatta atttcttgat
    17641 ctgtttcttg ttgacgttct tcaaaggtgg ctaataaatc ttcttgtgca agctcatgcc
    17701 aatttgttga ttggacagac tctaactgtt ctaaaagtgt gcctttaccc tgtgagatta
    17761 attcttcttt actctctaaa aatgcttgat aggtttgggg taattgatat ttcgaataaa
    17821 gctcatttaa aaataatttg tttttttctt tcatccattc atgctctggc ggatattgat
    17881 ccaaaatata atcaaataca gttgcctttt gtatctctat ttcgtttttt tctacttctt
    17941 cactgataag tggttcaata tattcctgag aatccccttc agtccatgtt gactcttcat
    18001 tagcttcaac tggatcaact tctacttcgg ccgtctcttc atcctccatt gtttcttcaa
    18061 agggatctac ctccaattga cccatcacat cgttctcttc ctcaaatatc gatttctgag
    18121 tcggaatatc agcttgttcg tcaacataga ctgtctcttt ttcttttgac tccttctttg
    18181 gaaatattgg tcgttcccat ggtacttctt catttacttc gacttcactc ccttgattca
    18241 cttttctttg gtcgctctct aactcttctt ctaaaacttg taaaagtttt tcgtttcgat
    18301 aagactcttc cacactcata gtttcatccg tttctttaaa cacatcaagg cggattaaat
    18361 ccatcaatgt aggatagaaa ccttctgaaa tttgataatc cagttgccca aaaacgtatt
    18421 ctgtaccagc tttctctatt tttccttctg tgtcatgtaa cgtgagagtc aacttaacag
    18481 aagatcgact ttcgtgttcc agtactttcc ctaacacatg tagctgttct tccgtttcaa
    18541 tgacagaata tttaattgtt ttcggtaaaa aagaagtacg ctttcctact tccttcgttg
    18601 ctttttttat taactcttta tctgttttgg tattgcctgc aatcgtaaag tacatgagta
    18661 ttctcctttc ataaaaaagg agtaaaaagt atcgactact tcttactcct acttttttac
    18721 tttcttataa tccttgaggt gtttgtccaa acaatccaaa taacgaaacc acaatagaag
    18781 ctgctgctaa aataactcct acccccatca atacatagcc tacgtgcatc ttcccatttt
    18841 cagctcctct tcgtccaaat aggaagaaaa gacccccaat aacaatggaa gcaacggccg
    18901 cagcagcagc aaaaatcatc agattgtttt ttaaactagt tgcggcagtt tgtaatgctc
    18961 taaaaatatc aaccgcagct actactttcg gttgtgttaa aaaattcatt gtaattgatt
    19021 caaacataaa attgttcgct ccttttagtg tttaataatt tcgtcgaaaa caagcttttc
    19081 acgttcacgt tgatagatat atccttctaa gtccttgtct tttccccgta ataggtcaaa
    19141 ttgtgctttt tcaaggactt cttgtttcca ctgtgtttca gatacaccgc ggcgttctaa
    19201 gattttagac gcggcttttt caaatggcgt tttagctttt gccactgtga ttcctccttc
    19261 aggacaaata aaaagactag caatcactcg ctagtctttt gtaacttata tttattggat
    19321 tgtgatccat cgtgaatcaa tttctctttc gttcgctttt catccttgct agatccaaga
    19381 aaaattattt tttttacgcc attcttctca tagggaacaa caataaataa agaatcagat
    19441 ttgtttataa attccctaac accagctgaa tctactattt tgtatctttc taaaccttta
    19501 tagtcttttt gcctcttgac tgttatttgt acaggatctg gatgccatac actctcagag
    19561 tattcccagg tagtctcgtc tataattttc aaattataaa caagaccacc tacttcttct
    19621 ttccacatag ttcctgattt caatacgcca ttatcttgat tagtttgttt atttttttca
    19681 ttactacatc cgactaaaat aacaatcatg gcaatcaagg aagtaactac tattattaac
    19741 tttttcattt tattcattct ttcgtttttt tattttaaat gtatctcaga accgcataac
    19801 taaaagttgc taacacaagt aatagtaagc tgaccgctga aatcgttact aaatgtgtag
    19861 aacctgtttt aggaacaatg acctgtggca agttaggatc aaccccaatt gtcacaacat
    19921 ttgttttatt agaaacatta tctactgcta ctacggcttg gttatcaata tttttttctg
    19981 attgtaatgg agttttagct gtaaatatca gctgaatttc tcgtccatct aaaagattgt
    20041 tacttaagaa gtcagcggaa gcttcccact tcagcgttct tgaattgcta tcataggtta
    20101 gtgtgccttc agaagtaata tcttttcctt tactcttatc tattacttgc gcagaacctt
    20161 ctttatatgt caaacgagct tcaattggat cttgaatact aaattgtttg tagtgatctg
    20221 acgcagcgtc tacgcctttt gtgtgccatt tttgtgtgac tagatattgt acttcagatc
    20281 ctgcgtttaa aggagctgtc ggcgtaccct tcttaccgtc atttcgtccg tttacatctt
    20341 ttccattttg ttgtacttct ttcactggaa ttttagggaa ataaacggta atgatatttg
    20401 tatccttttc tactttatta atgatcgacg ttccctgatt tttggctaca ctattttgat
    20461 tggccaattc attgactttt acattgatca ctaattcgta agtttcgccg ttatacttca
    20521 ttcgattttt taatgtatca gctttcgctg catattttac ctggtgtttt gttttgtcat
    20581 aggtcacttc accagataca tcgaattttt tatttgtacc actttcaacg tgtgcatcga
    20641 cgtaatttac ttcttttggt aaattatcga ttaactcaaa tcgatcgtaa accgctagta
    20701 aatccactcc taatcgattc accttctgtt tgattcgata ttgaatcgtg tctcctactt
    20761 gcaacatttt atcgttcacg ttatttccat ttttatcaac ccctgttttt tcaggttgat
    20821 caggaacaac actaaagatt gtcgcagaag ataaagtaaa ccaggtttga acattagaag
    20881 aaccaatcac aaacgtcgga tttgcttcag atattttaaa ggacacagta ccttgaccaa
    20941 acttcggatc tcctaattta tcatgcaaat tattgaaatc attatccgct tgtgtcagct
    21001 tagagcttcc tcctgggtgg ccacctacca cgttcagatt gttgtagaaa gatttaaatt
    21061 ctgaaagaac cgtatctttt ctgacatacc aatctgtcgt attcattttg tcatagtggg
    21121 catattctcc tttaagatcc gtggtttttc ctcctgcagg gttcaaagag ttaaaactga
    21181 taaatgtatc tcctgaaaat tgaacggggc taccgtcctc atatgtggct actagctgca
    21241 cattcatttg tgttgaatgg taaacaattc ctgagaaaag attgtctgag atccaaagta
    21301 ctgttctttt tttagattta ctcattgcac cattcgtatt tttatagcca tcgtctcgaa
    21361 aatgagtttt tgtatagttg ttatctagta gattccacgg caacgtatcc gagtataagt
    21421 gaatattaga tagaactagc ttgatattga cttttttccc gttatacgta ccgatttttc
    21481 catagtcaat attgactttg gtgttggttg ttacgccttc taaaacaagg tttgtttcac
    21541 cgtattcttt ttggaaagaa ggatagcgta tatttttgtt tccctccact aatcctacgt
    21601 agtcgtctgt aaaaccacct ttgttggcat caacatgata tttgtaaact tttgacgctc
    21661 cgtttacagt aatatttgtt tttgcattag gaacatcttt tggaataata aaattattct
    21721 ttacgttctg gattggattt gacggatcga caataacttt ttcagcaaag acattggctg
    21781 tttttaaccc aaacaatgta cctaacatca tcattatggg aaaaacatat tttaaccgtc
    21841 ttgtccacga gtgtttaaaa ttcatccctt catcccctct tttttataaa tgactagtga
    21901 aattccgaca ataacgatca aattgatcgt agtaaataat ggattcctaa tgagcttttc
    21961 cataatatct agcggcatgg aagcagctgg tatgtttaaa atcctcatta ggtatagttg
    22021 gtagcttggc aaaatagata gtttagaaaa taataaaccg cagtacaaaa agactgcggt
    22081 taaacaagaa aaattgaata ataataattt gatcagtttc attttatttc ttccttaatc
    22141 tctagaaaac aagtgagtaa caaaatccca acaattctca aagaagtttt tctttacgcc
    22201 agtagaaacg atttttttta cttcttcttt aggttgcgaa gcttctgatt taggatagat
    22261 ccacacatcc tttaagaatt caccgttttt atcagaaaca ggtgttaata gcaaaatatc
    22321 ctcgctatta gaaatgtttt caggacttga ttcattgaca atataataag cttgtttctg
    22381 atttgcctgt acttctatcg agaattcaaa gacacctgtt tgttgatcaa ttgtctttgt
    22441 ttttccatta gaaactagct tcaattgatc actgaatagt tttttcactc gatcttttaa
    22501 ttgggattca atttggtcag tagtgagatc cttaacatcc atcttttgta aaatgtccga
    22561 tacatcataa acagaaaact tcgcgccatt tactccttct tgtttttcaa gtttttgccc
    22621 ctggttgtct aattgttcgg aagaaataat tttttgaacg tgaatggtct gtttgactat
    22681 ttgatcgtct tcagcaattt tcggttcttc tgaagaatca actgttgacg aatcgacggt
    22741 ttcatcgctg ctttgaatcg tgctgctatc tgacgtttgg attgtttgtt ctgtgctatc
    22801 cgtgctttct tgtctgtctg caaacgtcaa ctgtgtgtag gcagtgaaag aaaaaagagc
    22861 ggctgcacaa acaaatagcc attttctatt tctcatgttg gttaccctcc tttatttttt
    22921 ctttttataa acaaatagcg aaccaatgat catgactgaa agaaaaacag tacttcctaa
    22981 aagccatgtc caagataatt tttgtttctt attttcttca tcttttaatt ctgattttgt
    23041 aaaggttact cgcttcccat acactagaaa acggtgtgtg ttgatcccct taggcgtaca
    23101 tgtcattagc gttactcgat cttcattggg atttggttct aagtaagtga caaagtttct
    23161 ttgtagttcg tctttttgca cttcctcaat ccgatcgatt tgataagcgt gctgctcacc
    23221 atcaactttg atataaaact tttctccctt ttttactgaa ggtaaatcat caaaaagatt
    23281 atctttataa agtccactat gacctgcgat taaaggattt ttaccgtttc ctcctgtaat
    23341 atcaccagtt ccttccgtaa tacctacacc attttctaaa attttgtcgg acgttccgtc
    23401 ataaattggt agttttaaag aaatacttgg aattgtaaga ataccaacag gatcgcctaa
    23461 ctcaatctta gcaacatcca aagaagaatc cgtttctgct gccgttcctg ttcgatcgat
    23521 tgcgacaatc tgctgatttt gttggtattt cgccacgctc gcttcagcag gcatcaaaag
    23581 taagacacct acagctgaaa gtaaccagaa agcaatgatc catttaccca tgattcgctt
    23641 tttcttaggc ttcctgataa tcattggttt tgatccttct aggctttctt cttaaagtaa
    23701 acaactgcag aaagtgcccc tgctcctagc aacaagcaag agattaatac atacgtttga
    23761 aaaccgttgc taccggtcat tggtacggaa gctttttgat tgtttttgat cgtgattcgg
    23821 ttttcttctt tgtatgaatc tttgtctact ttgaaagaga tctctttcgt taatttttga
    23881 tagttttcag gcgcttttgt ttcttccagt gaatattcac cttcagttaa accagtgatt
    23941 tcaaagtgac cttctttatc tgattttagg atcgctgcat ttgctacatc gtctacccat
    24001 actgcttctt tgacaccgtt tttatccgta tcaactaatc caccataata ttttccttct
    24061 gcgtttttag cagcaaattc tgcgccttca agcggtgttg ctttgattcc tattccaaat
    24121 agtccgctat cgacttttaa gaattttgca ccataagtca caacgtcagc tttcgttttt
    24181 tcgtggtgtt cttcctgatt aaatggattg ttgttataaa cgaaatccac gctatttgtt
    24241 aatggattgg caacagctgc gctatcattt acatacatgt tataagtcat ttgaagatct
    24301 tgtccgtgta aacttgctac agtatcactt acttggccat tattcacgat aaaatcgatc
    24361 acaaagccat tttctgaatt ttggatttta taatctgtat tttcttttaa taccacagat
    24421 ccatctttat ttgttacttt gatatttgct ttagcagcga cataagaaag tccttgtcct
    24481 gctatatccc cccatttaaa tacactgtaa ggagaagttt cgcttttcac tccgtttact
    24541 gtgataccgc ctgctccgcc tgcaatgtct gttgggatat gaatcgttcc ttgataattt
    24601 actgcgtcac caatttggaa agaatgttct tgtcctgttc catttgttac tgttttatcg
    24661 atcactggtg ctttatagtt tacgtatgaa gcttttaagt cacttgtcac gccatcattc
    24721 gtaatttcaa aggttaattt attgtgcgca tcgttgcgag cgtctgcgcc taataaatat
    24781 tgatctgctg ttggttcttt atctgatccc actacaactt ctgaaggaac ttccacaaaa
    24841 tagtattttc ctaacgtcaa atcagtagca gtcagctttc cttgatcatc cgatacaaga
    24901 tctcctaatt ttgttccttt tccaggttcg cccttgtata actcaaattt tgcccctttt
    24961 aaaggtgttt gtttgctttg agctgtgcca tcgtcaccaa atttcgttaa ttcaaaactc
    25021 aacttagaaa caatattttt aggatataag tgaatgtctt ttaaaaaacc tgaacctgta
    25081 ttatcagtca ttggcgcaat cacaaccatt ggttttgctt tttgtgtgac taatccagca
    25141 gcggatttac tttcataaac cacatataca ttccctttgg aattgacata ggctggttga
    25201 tcagcaaaag taatctcacc attttcatct acagctgaag taattttatt ggttgcattc
    25261 ttgacgtact cactgttaga tcccttgtct tctacatctt taacgatttc gtccactttc
    25321 gcgttggtta gatcagaatc ttcagtcggt aatacttgat ccgtaatatt tcctaacgta
    25381 aactccacat caccataatc tgccttgttg tatttcgtta cacctgtagg atattgatcg
    25441 tgcgtataac catcgttttt gatcccgtca atatcaacat tcaattgcgt tccttgatcg
    25501 tacattaatt tatgaaccgt gatattgacc ttctctggtg gcgttttttg tgtgacatct
    25561 tctgcatatg cttgataccc ctgaaagcag cttgcaatga ttcctaacat tccaacaagc
    25621 attccagctt tttttacata ccgatttatt gccatttttt tatctcctca tttcatattt
    25681 caacgactcg cgttgattaa aaccttgtta ttgtagctct ccctgtacca cgtatctttc
    25741 ttttccttgt gacgtataaa cacaagtaaa caacgttaat aagggtttct ctcctttctt
    25801 tggcaaagac aagaaagagt tctcttcagg aacgccatcg attaatttaa agtactcagg
    25861 tacgataaat ttacgcgtta ccttgtaacg atagacgcca tcgttactaa ctaagtccat
    25921 cacctcccct aatgacaact tttgaatatc agaaaataaa acacctggca tttccatgtt
    25981 atgacctgct aggacatagt ttcctttgcc catttcgcca tcttcataaa aataagtagc
    26041 cgctccaaga ctcaaagtgt attgatttgt ccctttaaaa attggcaatg ctaaaccaag
    26101 tgcaggaatc tgaatttgtg caaatacttg tttattgacg cccatttcga ttgcttcttt
    26161 ttgtatggac aacatttgac ccaaagacat atcattattg acgttcgttg catcctcctt
    26221 ataactcttt gcgtgtgcat tgatttgatc tacgggtatc tttttttcta tattttgctt
    26281 aaacacctct ccttcatgtt tttggtagct aacatagcca aacacactgc aaaagacgat
    26341 taaagcgact cctaaaaaaa aaataaccat tttttcatcc atctgcctcc tttcagataa
    26401 aacaaaaaac actttttcac aacgaaaaag tgttttctct tattactttc tatttcattt
    26461 atctggtggt tttatattgg tgtgtagcca ttgctaacat taagaataca attggcaccc
    26521 aactgattgt agttaatgtt tcttccatga atgattgaca catgatcgct aaaaaagccc
    26581 acaagaatgt tagttgtccg tttgtcagct cacattttct tacgagcaac cataaaaaac
    26641 taagcaaagg aataatcgat agagcaaaac caatcaatcc atagtgattg acgagtgcgt
    26701 gatacgtatt atggttacct agaatctgat ttcctatatg gaaaaagaaa ggtttcatcc
    26761 ctacaaatat ttgtcctgtt ttttcgccta atgtttcata gaatttgcgc caaatttctt
    26821 ctcgtcctgt aaataaatga actttgtctg acattgcagc aaaataagaa atcggtaaag
    26881 ctagaaccga aactgctgca tacatccaaa aggacaagtg tgtgtttcga aaaatcttct
    26941 taggtaaaat ttctaggata acgaagataa caagcgcgta taatgctgct ttcgattggc
    27001 aaacccaaat cgttgcccca gcaagaatca acgctggtaa tgatagcaat cgcatgtacc
    27061 attttacaaa tgaactagca aatcctgtga taagaagggc taatgtcatt aaagaactac
    27121 ctatcgtatt tgtattgatc caaatatctg ataatttgtt cgatggattc caaatacttt
    27181 gtccttctgg tactggtatc tcggtaaata ctcgataaac cgttacgagt aaaaagacat
    27241 agaatactac aagatacaag ctacgatcaa acacagtaaa ttccgtccat tttacaatca
    27301 aaataatggc aataattgtc ggaacgatca gatcaccata gaaagtatct actcggtagc
    27361 ttctaaaaaa agaaaagaaa aggtaaaaaa gaatgcctgc tgcaatgaag aataaatcgt
    27421 ttctctttac cttgtacaga ttcaaaagaa acaaacagcc tacgaaaaac gtcactaact
    27481 gtgcagcatt atcataaata atatcgtagg aggatttaac cccaccgtcc atattaaata
    27541 tagaatggat accaacagta acagaaaaat ggcactcatt ttattgatca atttttctac
    27601 aagttcttga atgtgactca cttcccttat ttattgattt tttctacatt gactaattcg
    27661 cactggatca catcgcactt tttcatatta tttgcttcaa agtctaacag tgtgagtagt
    27721 ggttttttac ctgcttttgg caaggataaa aaggaattgt tttccttaga ttgaactacc
    27781 tggctgtaat cataaatttt tcctcttttg gagacttcat actgatactt gtaatgagca
    27841 tcgattagat caatttcttc tccttcagat aaatcaatca tatcggataa taaaacgctt
    27901 ggtgtatcta cgttataacc agcaagaata taatttccat ttcccatttc agcatctgga
    27961 taataagtag aagctactcc taaactaagc gtatcgctat tcgctccttg aaaaacaggg
    28021 agaataaatc ctgtagaaga aaaaacaagt tttccagcaa tttcaccttt gagatccttt
    28081 tctaatgcct gtttttgatt agtaataagt tgtctcttag aaatatccgt taaactggtt
    28141 aaattatctt gataggtttt atcctgttcc tgaatatgga ttgtttttgt tacaccatct
    28201 actttttcag cgattttgtc cttttgatga ccttgataag caaaataact aaaaaggaga
    28261 aaaacaatga ttacgcccac gtaaggatta aataaagttt tattgttttt attcatctat
    28321 ctaccttcta tatttgaatt aatttaccta catctaacca agataaaccg cgttaaattt
    28381 tactattctt tttattaaat aacaatgcca catcataatt gatcattttc atatcataat
    28441 cgtcaagaaa cttctaataa tagttggcaa ttagatctta ttttcacata agttcgtctc
    28501 aactgttcaa aatttttcat tgatcccaat agacaggctt tctcctttcc tgttatctgc
    28561 atgtcactga tatattgcat gacagataac cttttaaggt gtttttgttt catcgttttt
    28621 agtaactttt cttccatttc tttcgacact tttttctatt ttcgatttct ttacaattca
    28681 tgagttttcc taccttcctt gttttgataa aaataaaaaa gcctatgatc acatacgctc
    28741 tacacttcac tcttgggtta tctttttctt tcttttaact actggccttg ctggtttcaa
    28801 atccttgatt ccattataga ttctccaata atcaaactct tttcgtaatc tttctttttc
    28861 catatctgtt cctttggata aggctttaaa tacatcttta ggtgaataac tacgagctaa
    28921 cagctgtaca taccttcctt ttgtcaaagt atccatatcc atcgcatcta aaactggtcg
    28981 cgccatctaa tttgcctcct aaataaattc tttactcgat gtctaatgat aatactagct
    29041 ttttattatt cgtcgtaatt tctgcacatt cttcttcatt attttctgcg attaacgcat
    29101 aatagcatgg tgattttact tcgaaaaatt tcatgatcta ttcctccaat ttttattctt
    29161 ctttatccgc tacaaagtca atgatttcaa cactgacaat ataatcactc aaatatgacc
    29221 aggtatcttc tacagacaat tcgtctcctt tgtcgttcgt aagcgtcatt ttaaaccact
    29281 catcgccttc atcatcttca ggtagcaagc cgaatccaat tggattatca gtcaatgttt
    29341 aatcgtataa atcatcctcg tctaatgcta aaacatctaa tcctttacaa tttccgcctc
    29401 ttctaaacgt cacaaatcct ttgtaatccc aacgttggaa agaaacctta atagtatgtg
    29461 tgcccaatcg tatattcgga tcataatttt tcatttgtca ttcctccatt acgtaaattt
    29521 cattttctct atgttttata tcaatttttt cactttattc aggacttgtt catattttat
    29581 cgtttttcgt ttacttaaaa atacataaaa aatttcgact cgtttatggc gtccgaaacg
    29641 agaaacccta gtagacagcg gtaaatgctc gattgatcca ataatcaacg tcctcgcaag
    29701 tatctacatg tactgcagca cacgacacaa tttcttgtgc gtcctcccca ttacgagaag
    29761 acctactcct tattccatga gtttgcatta aagtctagat cccttagtag ctgctcatga
    29821 ttaatctaga cgctattcta acttgtctaa cttctaaatt ccctcttgtt tactctgcgc
    29881 ttattattta cacaaattca tttcaccact atccaaacaa gcgcatttac tcgattgacc
    29941 aattttttac gttaccaatc gttaaaacct accccgtcac tccccgaagg gaattgttga
    30001 tagatcaagt ctactcctta tttttctagt gactctaagt tcctttagaa gtctcgacaa
    30061 tattttcaag caagcgaaaa acgataaaat acaagttatg agaatgatca attcagctga
    30121 tcaaacgccc catccctttt gcggtacaac gcaagactcc attttttctt cgaccaatca
    30181 gtacaccgtt ttggtcataa acatgtttga ttgttggata tagctctttt aaggggatag
    30241 gatcttttaa aattatttgc ttttgtttcc caatgtaata aatcatttcc tctgagactt
    30301 tgtctttctg gattatatat ttcttacact gcacaacggt tttactttgg ccagttgata
    30361 gtttcttcgt gattttctct gtagcggtac accgtttacc gtagtgacaa atatctttga
    30421 gactcaaaat tcctgtatat gacataaaat aaaccaccca atttctttaa atatttttaa
    30481 caagtttttc ttgttatttt tcaaaaatag agaattgatt ttcgttcatg acaaacaaaa
    30541 aagagggaac gcatccaaac atgcgttccc tctaatttca gcgttcgtca tacggcaaag
    30601 agccacacgg acatttttat aacattatgc ttaggcatag attcatcgta atatcacgta
    30661 tttttaacct taacacagcc aaaaaaagtg gtatcacttt tgaatatctg ttatactaaa
    30721 tccgttgcgg gtaataccgt aacactgaaa ggttaacgca ttaagggcca aatcttaatg
    30781 ccgtgtatga acgctgacga agattaccag ccttccgagt tcataccgcc tttctttttt
    30841 ttgtattttc aattgtccaa atttatcgtc caaaagtgca gaacgaaaat caattcatca
    30901 caggcatagc agacaattaa atttatacaa aaaaatgtaa gcgaataata ttcgtattgc
    30961 ctgaaaagaa gtaatatcaa gatttttagc ttgtttaaat aatgaaatta tctctcttcg
    31021 cgtattatta taactcaaaa aaaaggagta tgcaaacata cgttcccttt tctatatttg
    31081 aaattaatta tttcttttaa cacttatgac gtaaaaggct acgtttgtga tttttatcat
    31141 aatattttaa cttataaatt ctattaaaat agctattatt ttgtaatatt cgtaatataa
    31201 ttagaataat aaaaaatttt taattttaat gttactccat gaagcaacaa tcactttgtc
    31261 agtaaagttt cactctaacc agtctttcgt aatagtgctt ggggagcttt cataattcaa
    31321 acgtttttca cttgatactt tagcagctat tggtttttcg ataaaccaat tttttacata
    31381 gacaaaaatc aggttctgga tattttcgac tttttcggtt tttaattttt gataggcttt
    31441 taacagtgtc gtgtataatt cttgttctgc attgacataa taactatcga gttcttcaaa
    31501 aactatcgaa ataccacttt ctatttcagc ttttttcttt gcattatgaa tagtctggac
    31561 ggttttttga gcttcactgt aacttgaaga aaatgttttt atcaaattta atactcgttc
    31621 agggacaaac gtagcaatgc tgtcgtttgt cataattgtc tcaaaattgt ctaacaacaa
    31681 ttgatcttgt aggcggtctt tttcagtgtc tatattgtgt ctattagtgt ctaatatatt
    31741 attattaagt tctggtatga ttttcatacc ctctgattta tcaacgtttt ggcacggtat
    31801 gattttcata ccctcttgag ccccaaggga ttcagcgtct gatttttcgt cgagggtggg
    31861 tatgattttc ataccctctg atttatcaac gttttcccta ttctctctat caaatttttc
    31921 gagtaagtag atatcatttt ctgagacttt taattctgct agatatagtc tattaggatt
    31981 atttttccct aactgtttgt taaatcccat ctgcttttgt aataataaac caaaggattc
    32041 caactctttt ttgattgcta tcgctttttg tttttggcag tttaatacgc tacatagttc
    32101 atttgtcgta taagtaaaat aaacattacc ttcttcatcg atttgccgtt tgctgattgc
    32161 gatctctaat cttgctttta aaagcatata ggcaatctta gttgaatctt tcattttttt
    32221 gtattcgtca gaaacaataa agacttttgg aaattgataa aataattcgt tataaactct
    32281 atccgcctta aaaaaattaa aatcagtcat tgtagatcct ctactttcac gttgttttat
    32341 ttatgtaaaa ttacctactc ttttcgaaaa tagcaaagat aaataaaaaa tgcaaacgca
    32401 ttaaaactgt tttttaatta aatactacct aaaatcagaa ataaaatgaa ttatgtacta
    32461 cctttaaagt cattaagaac tactttaaat aaatattatt tataattaaa tactaccaga
    32521 agaacgtatg aataaaattt agttttaaaa ttaaagataa ttaagtacta ccagtgtcaa
    32581 aacaaaaaat aaattaagaa ctaccttatg catataaaac atactaccat tactagtgat
    32641 atatactacc ttatttcagt agtatatatt atattattct tataagacaa ggctttaggc
    32701 tagaaaacaa tagattatat actactaaaa aatacaataa gtactaccaa tgtcagatat
    32761 atataataat tatgtactac cattaaaatt aacttattta ataagatact actgtgttaa
    32821 tctgaaaata attactttaa agtagttaca tactacctgt taaattagat actaccatta
    32881 atacttaaat tagatactac ctatatttat attaagtact accgttctag gaataagata
    32941 ataaaaaaat actaccaaat tgcaattaaa tactacttaa aatgtaaaaa ataagaacta
    33001 cccaaattag gtagttctta ataagagaat atcagataaa tttgtataag tcataaaaaa
    33061 attaatctta aatttttaaa tatatatact tgtt
//
LOCUS       DAPBBR010000029        31839 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPBBR010000029 DAPBBR010000000
VERSION     DAPBBR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.029"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(148..2301)
                     /locus_tag="RD488_001520"
     CDS             complement(148..2301)
                     /locus_tag="RD488_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDT7657598.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2595..3443)
                     /locus_tag="RD488_001521"
     CDS             complement(2595..3443)
                     /locus_tag="RD488_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7657599.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="RD488_001522"
     CDS             complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="RD488_001522"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDT7657600.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5944..6123)
                     /locus_tag="RD488_001523"
     CDS             complement(5944..6123)
                     /locus_tag="RD488_001523"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDT7657601.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6170..7993)
                     /gene="cadA"
                     /locus_tag="RD488_001524"
     CDS             complement(6170..7993)
                     /gene="cadA"
                     /locus_tag="RD488_001524"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7657602.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8271..10550
                     /locus_tag="RD488_001525"
     CDS             8271..10550
                     /locus_tag="RD488_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7657603.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10643..11290)
                     /locus_tag="RD488_001526"
     CDS             complement(10643..11290)
                     /locus_tag="RD488_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657604.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11469..12188)
                     /locus_tag="RD488_001527"
     CDS             complement(11469..12188)
                     /locus_tag="RD488_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7657605.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12319..13470)
                     /locus_tag="RD488_001528"
     CDS             complement(12319..13470)
                     /locus_tag="RD488_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDT7657606.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13687..14427)
                     /locus_tag="RD488_001529"
     CDS             complement(13687..14427)
                     /locus_tag="RD488_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7657607.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="RD488_001530"
     CDS             complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="RD488_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDT7657608.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="RD488_001531"
     CDS             complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="RD488_001531"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDT7657609.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15388..16038)
                     /locus_tag="RD488_001532"
     CDS             complement(15388..16038)
                     /locus_tag="RD488_001532"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDT7657610.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="RD488_001533"
     CDS             complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="RD488_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDT7657611.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="RD488_001534"
     CDS             complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="RD488_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDT7657612.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17481..18008)
                     /locus_tag="RD488_001535"
     CDS             complement(17481..18008)
                     /locus_tag="RD488_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDT7657613.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18188..18973)
                     /locus_tag="RD488_001536"
     CDS             complement(18188..18973)
                     /locus_tag="RD488_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDT7657614.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18966..19835)
                     /locus_tag="RD488_001537"
     CDS             complement(18966..19835)
                     /locus_tag="RD488_001537"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDT7657615.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19836..21215)
                     /locus_tag="RD488_001538"
     CDS             complement(19836..21215)
                     /locus_tag="RD488_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDT7657616.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="RD488_001539"
     CDS             complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="RD488_001539"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7657617.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21667..22143)
                     /gene="accB"
                     /locus_tag="RD488_001540"
     CDS             complement(21667..22143)
                     /gene="accB"
                     /locus_tag="RD488_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDT7657618.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="RD488_001541"
     CDS             complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="RD488_001541"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDT7657619.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="RD488_001542"
     CDS             complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="RD488_001542"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDT7657620.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="RD488_001543"
     CDS             complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="RD488_001543"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDT7657621.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25173..25397)
                     /locus_tag="RD488_001544"
     CDS             complement(25173..25397)
                     /locus_tag="RD488_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7657622.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25450..26412)
                     /locus_tag="RD488_001545"
     CDS             complement(25450..26412)
                     /locus_tag="RD488_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDT7657623.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26422..26862)
                     /locus_tag="RD488_001546"
     CDS             complement(26422..26862)
                     /locus_tag="RD488_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7657624.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27168..28133
                     /locus_tag="RD488_001547"
     CDS             27168..28133
                     /locus_tag="RD488_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7657625.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28190..28420)
                     /locus_tag="RD488_001548"
     CDS             complement(28190..28420)
                     /locus_tag="RD488_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HDT7657626.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28506..29393)
                     /locus_tag="RD488_001549"
     CDS             complement(28506..29393)
                     /locus_tag="RD488_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDT7657627.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29482..30705)
                     /locus_tag="RD488_001550"
     CDS             complement(29482..30705)
                     /locus_tag="RD488_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7657628.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30722..31768)
                     /locus_tag="RD488_001551"
     CDS             complement(30722..31768)
                     /locus_tag="RD488_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7657629.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
BASE COUNT         8794 a         6970 c         5486 g        10589 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa aaaagaaaaa atgggcggag caagaaattc tttacctaat
     2401 ttcaagataa aatcaacttt ttgtttcaca gcaatcactt aaagttacat atccaactat
     2461 ttttttcatt aaaaaataaa cttatttttg aaaattatgt tttcttaagt cgtgaaacac
     2521 tttgatggat catttatttg tggaaaacta cgttttgtta ttctaaaaaa cttatataaa
     2581 aaatagtaag gtttttattt cgaatccata aaatattctt ggattgcttc tcgtgttttt
     2641 ttcacttttt cgctaagctt ttcgttttta gccatataga aataaaaaat gatatcgatc
     2701 gtagcaaatt gggccaaaag tgaattagtt gccgcacttc gattcgtgat ttcttttggt
     2761 ctagatgttt gtacgagtac atcggctatc ttgctaagcg ggttatttcc aaattgcgtc
     2821 aacgcaatga tttcgatatt catgcttttc gccagctcgg ctaatgcgac tacatctgca
     2881 cttctacctg agtttgaaac aagccaaagc actttctttt tctcattgct gacaagttgc
     2941 gggagcaaga cgtggatatc tttttcaaaa atgattggct taccgacacg agaccatttt
     3001 tgcagaatat cttctactac taaagaagag gcgccaaccc catataaaaa aacagtctct
     3061 gccgattcca aacactctac gactttttgg atcgtttctt cttctagaat atctactgtt
     3121 tcttttatcg ctacttgtgc attgttacca agtttgtttt tgatagagta aaaggactca
     3181 tttgcttcta tatcactaaa accttcatcg attccagtct gtagttctgt tgaaatcgtg
     3241 attttgaagt ccgtcagact ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc
     3301 gcactcaacc cggaagcttc tgctaattca ttagctgtca ttgtagggac cttctcaata
     3361 ttaccgataa tgtagttggc caactttttt tctgctgaag aataatcttc catcatactt
     3421 tcaatacgac taattacgct cataagttcc tccacccttt taatgatagt ctatgtaagt
     3481 ataccatatc agacccttat tcacggtcgt atactggata aaaaacaaaa aaacaatccg
     3541 cccaacagaa tatcttatcc catcaatccc acagattcta ttgagcatct gtgtctttga
     3601 ggaatacctg ttatctattg ttcggattgc tttctatcta ctactttttt acaggaaatt
     3661 tacctattag ttttctctgc tgtaattttt gacttctgct tccatagcat caataaagat
     3721 attcaaatct tctacagctg tttctttact tccataacga cgtacgttca ctgttgcatc
     3781 ttccaattcc ttgtctccaa caactaattg gtaagggatc ttttgtgttt gagaggcacg
     3841 tatcttatag cccatttttt cattacgatc atcaacttct acacgcaacc ccttcatttg
     3901 caaacgttct ttgatttcat aagcataatc gccatgtgca tcaacagaaa cagggatgat
     3961 tgttgcttgt ataggtgcca accatgttgg aaaagcgcct ttgtatactt ctgttaaata
     4021 agcgacaaaa cgttccattg tagaaacaat tccgcggtgg ataactactg gacgatgcgt
     4081 attttccccg tcttctccaa catatgtcaa atcaaagcgc tctggcaata agaagtctaa
     4141 ttgtatagtt gataatgttt cttctgtacc aagagctgtt ttgacttgaa catctagttt
     4201 tggtccgtaa aaggctgcct cgccttctgc ttcaaagtaa tctagttcta attcatccat
     4261 agcggctttc agcattgctt gggctttttc ccacattgcg tcatcatcaa aatatttatc
     4321 tgtattgttt ggatcgcgat agctcaagcg gaaacgataa tctgtaatat tgaagtcagc
     4381 atatactgcc accatcaatt caagcgtacg tttaaattca tctttgattt gatcaggacg
     4441 aacaaatgta tgaccatcat tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc
     4501 acctgatttt tcatagcgat gcatcattcc taattcagcg atacgaattg gtaattcacg
     4561 ataagaatgg atcgtgtttt tgtagaccat catgtgatga gggcagttca ttgggcgaag
     4621 aacaagcatt tcgccatctc ccatatccat tggcgggaac atgtcttctt gataatgatc
     4681 ccagtgtcca gatgttttgt acaactcaac atctcccatt attggtgtat atacatgttg
     4741 gtaacctaga ctaacttctt tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc
     4801 cccttttgga agccagaatg gcaaaccaga acctacttct ggggaaacca tgaacaagtc
     4861 aagttctttt cctagtttac gatggtctct ttcttttgct tcttcacgga gacggatata
     4921 ttctttcaaa gctttcttgt caaaaaaggc tgtcccgtat acacgttgca tcatttgatt
     4981 gtttgagttt ccacgccaat aagcacctgc cactgataat aatttaaata cttgtatacg
     5041 gccagtggat ggaacatgtg gtccacgaca caaatcgatg aattcgcctt gttgataagc
     5101 agtaatcact tcttcttctg gcaattcact aatcagttct actttgtacg gatcacttgc
     5161 aaaaatttct aatgcttcct gttttgaaag aacacggcgt tcgatcggca gattttcttt
     5221 gacgattttc atcatttctg cttcgattgc cggcaaatct tctgcagtta cttggttttg
     5281 tccattatct gtatcgtagt aaaaccctga atcgatagct ggtccaacgc caaagtggat
     5341 atttggatag aggcgacgca tggcttgggc catcaaatga gctgctgaat gacggactaa
     5401 gccaagtgca tcttcatggt ctggtgtgat gatctcaata cttgcatctt cctcgattgg
     5461 acgagtcaaa tcaacgagtt ttccgttcac tttaccagct aaagcttttt ttgctaagct
     5521 ttttgaaatg ctttcagcaa ttgccaatgt tgttgttcca gactcaaatt ctttgactgc
     5581 accatctgga aaagtaattt ttatcataat agtttcctcc ttgaaatgtt ttgattgatc
     5641 agatcatcaa gctgaaaaac aaaaaaatcc tagcatctct tgaaaagaga tactaggacg
     5701 aaaagttcgt ggttccacct aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg
     5761 tccgaccgcc cttgcttcaa caagggtttc gaaagtggtc atcctttggt tttctcctgg
     5821 aaaagtttca gcctagcttt tcctctctta tcgaagactc tcaaattcag ttggctttct
     5881 catcaatcaa ttatgtgttt atttaaccac taataaatag aaaaatcaag tgggaaacta
     5941 aacttatttt ttccattccc catttacacc gtatgttcct tttttcatct cattgatgat
     6001 gacatggatg tgttcttttg gtgcctgcgt gtttttatga acagcttccg tgatatcttt
     6061 catcatattt tctaattgtt ccggactgcg accttctact aattcgacat gtacgaatgg
     6121 cataatgctc tctcctcttt ctgatcgttc ttttttcaac tcgattctat catactatgt
     6181 ttgtcttggg tactgaatca ggaaaaatgg ctggatcttt ttttgctctc aaggcactca
     6241 aaatagagac cgtatccacg acttcttgca aaacagctcc gaataatgcg gggattagtc
     6301 ccgtacttgc aattaacatc aaaaaaatac aaataaagat gccaatcagt acagactgtt
     6361 tcgctattct catcgtatct cttgaaatca ctactgcttt tgctacacgc aagagatcat
     6421 ctttcaagat gaccgcatct gcactttcac tagcagctgt agaaccatga gcccccattg
     6481 caataccgat atctgcagca gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg
     6541 caacaggtct ttgatcttta gggatacttt ctaaaatggt cagtttatct tgaggcaagc
     6601 tacgggcatg tacagaatct aattggactt tttctgcaat cgtttgagca atggcagatc
     6661 catccccggt gatcatcatc aaatttttca catcaagttt tcttagctcc ttgattgtct
     6721 ttgctgcttc tgggcgaatc tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa
     6781 ttgttacata gattgctgta ttggacgttt ctatttcttc agctgaaaca aaagaggcac
     6841 gtccaatctt tacttcatga ttattgacta ctgcttggat tccttgaccg gtcacttctt
     6901 tcagttgact aacaggatac agttggctgt ttttcacgtt gttcactaac gaacgagcta
     6961 agatatggct agattcctgt tctgcactag ctgcatacag aagtagctct tcttttttta
     7021 ttccattgac tggctgaatc gcctctactt ccaatatccc tttggtaagc gttcctgttt
     7081 tatcaaaagc aatcgttttt gtacgtgcga gcttttcaat cgttgttcca gtttttacaa
     7141 cgatcccgtt tttacttgaa cggctcattc ctgcaactaa agcaatgggc gcagctagaa
     7201 tcagtggaca aggtgatgcc actaccagta cctcagcaaa tcgtaaaggg tcttttgaga
     7261 accaccaaga aataccaccg atcaaataag caatcaacgt gaaagggact gcataacgat
     7321 cagctaaacg gacaaatcgg gcaggctttt cttttgattc ttcgactagt ttaataatca
     7381 tttgatactg gctgtctgcg gcacgttttt cagcgatcat ttggatcgat ccgtctccat
     7441 ttaaagaccc tgacataatc tgatctccag gtttcttggt ttccgggcgg gactcacctg
     7501 tcaaagaaga ttcatcgacc gaagattctc ctttggtcac tcgaccatct gcgggtacaa
     7561 gttcgccagg cttgactagt aactggtcat caatatttat ttcatcgatt actatatcct
     7621 gcaattttcc ttctttgaat cgatgggcaa ttcttggggt gttatctaac aaagactgca
     7681 gttctttacc cgctcgttta ttcgcgtaat cctctagact atctccgccc gtaagcatga
     7741 tcaatatcat caaactagcc cagtattctt tgacggctaa tgttgcaagg attgcggtaa
     7801 tcgctaatac atctacgcca tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca
     7861 tcaagaaggc gagaatccct ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt
     7921 gaaaaacaaa ttcacttaat aaagctatcc caccaataag caaagtaagt aaaaattttt
     7981 tgaaatgtgt cattgttttt tctcctcttt tatgtgactt agagaggtta gtaataaatt
     8041 tccagctgcc tctttcatct taagcatagt ccttgactag cactttttaa aacaataggc
     8101 cttaattgaa aacaactatc actatcagcg tttccaaaat tcatcagttc tacaaacaaa
     8161 aatattcagc aaggattact ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa
     8221 ctatgctata cttttaattc gttatttacg gcggaaggag caaacatgcg atgaatgaga
     8281 aacaactaga acaaacgcac gtggatgaaa cgatcgaact aatccagatc gaacaaaata
     8341 tgctggatac aaaacaacaa gaattgactc aggaaatgaa tcattcgaca aaagacacag
     8401 ctaatcacaa gattcgagct ggttccaatg aagcttttta tgaatctgct gttgaatatc
     8461 gccaacatga gcaggaattg cttttgaaat accatactct tgaagcacag caaaaacgcc
     8521 tgcaaacgtt gtctgtcatg aaagatagtc cttattttgc ccgtatcgac tttaaagaag
     8581 accgtgaaac agaaacatta tatctaggta tcgcttcttt aagagatctg gcagaagaaa
     8641 caatcgttat tgactggcgc gcaccaattg ccaatcttta ttatgaaggt gagattggtc
     8701 ccgcatttta tgaaactgaa acagatagaa tagatgtcga tctgcagttg aaacgacaat
     8761 ttaaaatcca agaaggacgt attttatcta tggtagatac gtcggaagta atcaatgatg
     8821 actttttgct agagatattg gatgaatcat caagcaacca tatgaaaaac atcgtctcta
     8881 cgatacaaaa agcacaaaat gcaatcattc gggacacaac aagtaaagta atgctgattg
     8941 aaggaatcgc cggaagtgga aagacatccg ctttgcttca acgtattgct tttctgttgt
     9001 atcataatcg caagtggctc gaggctgaaa acgttcttct attttcaccc aaccatttgt
     9061 tttctgatta catctcgact gtattgcctt cattaggtga aagcggcgtg cctacacaga
     9121 cattcaaaaa ttatttggtg cagctgctgc cagagttttc tttactagat gaacagcaac
     9181 aagaaagtgg ttttttgcta ggggaaaaag atccgataca agtgatgaaa agcggattga
     9241 ccttagtcga tcagattgat cgctatatcc aaggcatcac aaactacggt cccttgttcc
     9301 gtgatatgaa aataaatggc cgtacgatcc tatcaaagga atcgattcgc caatggtata
     9361 aagaaacaaa tgaacaatta cctttacatc atagactttc tctattacaa acgaagctcc
     9421 tgaaaaaatt aggcggtctg caaaaagacg aaacacgtca gcaatgggtc aaagatctgg
     9481 cggaagaaca gctccaagaa ctatacgcaa cagatccaaa tcttgaatat acagaacaaa
     9541 aggagcgttc attacgtaaa aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa
     9601 tccatcgagg gatcatgaat tatcaatttg tcaatataac gaaacaatat ctccactttc
     9661 tacaaactgt gccactttct cttctaacac gacataaaat cagcgagacc aggtggcagg
     9721 aacatttgac aactgttcgt acacacttgc gtcaaagaga attgcgtcaa gaggatgctg
     9781 tactattctt tttactgatg cgccgaacat atccagtgac ggttacacac aaagctcgct
     9841 atatctttat tgatgaaatg caggatttcg caccatcaca agtggcattg ctgcaagcct
     9901 tgttcccaaa agcaaatttg actttctgtg gagatctaaa tcaaaatgtc tttggaaatg
     9961 aaacgatcgt tggatcattg gaagaccttt tcgtggaccg tgaagtcact cgtttccaat
    10021 taacgacaag ctatcgctcc acaaaagaaa tcactgattt tgctaatcat tttattgtga
    10081 aagaacatca agtagaaaca acagcaagaa aaggagacct tcctttgctc atccaaggaa
    10141 caacagatga tatcaaattg aattggttag cagataccat tcgaacgact cagggaaaag
    10201 cccggtattg gcgtacagca atcatagcta aaacacaaga agaatgcgaa gctctttatg
    10261 ctcaactgcc agacgagttg aaacaacaag tccagctgat tttaaatgag agtgacttta
    10321 tgaagcgttc cattatttta cttccagcct ttttagcaaa aggtctggag tttgaccgag
    10381 ttttcttgtg ggatgtagat gcagaacatt tttcttctca gcaagacaaa ttgatccttt
    10441 acaccatgtg tacacgtgcg atgcatgaat tgaccctttt tacctccaat aatgaaagtc
    10501 ctttgttaaa caatatggat atttcatctt atgagaaaaa agtactgtaa gtaaaaagac
    10561 aactgctatc attaatgtta gcagttgtct ttttatttac aataataatt gcagaaaaag
    10621 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
    10681 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
    10741 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
    10801 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
    10861 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
    10921 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
    10981 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
    11041 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
    11101 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
    11161 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
    11221 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
    11281 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
    11341 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
    11401 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
    11461 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
    11521 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
    11581 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
    11641 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
    11701 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
    11761 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
    11821 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
    11881 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccctcatag
    11941 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
    12001 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
    12061 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
    12121 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
    12181 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
    12241 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
    12301 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
    12361 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
    12421 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
    12481 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
    12541 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
    12601 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
    12661 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
    12721 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
    12781 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
    12841 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
    12901 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
    12961 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
    13021 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
    13081 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
    13141 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
    13201 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
    13261 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
    13321 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
    13381 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
    13441 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
    13501 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
    13561 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
    13621 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
    13681 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
    13741 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
    13801 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
    13861 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
    13921 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
    13981 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
    14041 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
    14101 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
    14161 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
    14221 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
    14281 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
    14341 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
    14401 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
    14461 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
    14521 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
    14581 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
    14641 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
    14701 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
    14761 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
    14821 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
    14881 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
    14941 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
    15001 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
    15061 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
    15121 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
    15181 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
    15241 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
    15301 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
    15361 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
    15421 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
    15481 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
    15541 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
    15601 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
    15661 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
    15721 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
    15781 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
    15841 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
    15901 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
    15961 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
    16021 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
    16081 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
    16141 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
    16201 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
    16261 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
    16321 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
    16381 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
    16441 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
    16501 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
    16561 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
    16621 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
    16681 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
    16741 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
    16801 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
    16861 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
    16921 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
    16981 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
    17041 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
    17101 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
    17161 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
    17221 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
    17281 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttggatct cattataatg
    17341 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
    17401 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
    17461 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
    17521 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
    17581 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
    17641 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
    17701 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
    17761 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
    17821 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
    17881 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
    17941 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
    18001 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
    18061 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
    18121 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
    18181 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
    18241 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
    18301 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
    18361 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
    18421 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
    18481 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
    18541 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
    18601 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
    18661 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
    18721 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
    18781 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
    18841 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
    18901 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
    18961 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
    19021 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
    19081 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
    19141 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
    19201 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
    19261 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
    19321 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
    19381 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
    19441 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
    19501 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
    19561 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
    19621 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
    19681 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
    19741 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
    19801 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
    19861 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
    19921 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
    19981 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
    20041 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
    20101 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
    20161 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
    20221 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
    20281 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
    20341 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
    20401 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
    20461 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
    20521 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
    20581 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    20641 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    20701 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    20761 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    20821 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    20881 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    20941 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    21001 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    21061 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    21121 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    21181 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    21241 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    21301 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    21361 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    21421 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    21481 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    21541 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    21601 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    21661 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    21721 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    21781 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    21841 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    21901 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    21961 ttcagatatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    22021 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    22081 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    22141 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    22201 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    22261 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    22321 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    22381 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    22441 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    22501 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    22561 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    22621 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    22681 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    22741 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    22801 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    22861 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    22921 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    22981 ggtacgaaca ttggagaaac tcgttttgca cctttttcat gtagacgaat aacttggttt
    23041 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    23101 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    23161 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    23221 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    23281 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    23341 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    23401 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    23461 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    23521 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    23581 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    23641 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    23701 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    23761 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    23821 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    23881 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    23941 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    24001 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    24061 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    24121 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    24181 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    24241 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    24301 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    24361 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    24421 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    24481 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    24541 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    24601 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    24661 tcggcgcatt catcactgca accattttcc cgcttccagc tggggtagct tctgtcatat
    24721 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    24781 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    24841 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    24901 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    24961 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    25021 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    25081 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    25141 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    25201 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    25261 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    25321 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    25381 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    25441 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    25501 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    25561 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    25621 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    25681 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    25741 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    25801 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    25861 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    25921 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    25981 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    26041 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    26101 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    26161 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    26221 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    26281 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    26341 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    26401 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    26461 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    26521 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    26581 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    26641 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    26701 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    26761 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    26821 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    26881 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    26941 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    27001 actgataaat cagcatttat aatttctttt attagaaaaa tcatctatct cacatatttt
    27061 gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt gtccattatt
    27121 tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa
    27181 aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga gatggtaagg
    27241 tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat tttcatcaga
    27301 ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat tttgatttcg
    27361 tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc caacattacc
    27421 gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta catattacca
    27481 ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct tttcgtctct
    27541 ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt
    27601 ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa atgacttttg
    27661 aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag ctactgactt
    27721 acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa gccggtatgc
    27781 ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa caaaagcagt
    27841 ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag agtcagaaaa
    27901 agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct ggtgacgttt
    27961 ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt caattgtcaa
    28021 aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta gaaaaagaac
    28081 agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc
    28141 tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt tattggatta
    28201 agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc tgatgagtat
    28261 ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta cacttctcta
    28321 cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg accatagcct
    28381 ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct ccttttctta
    28441 tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct aaaaaaactc
    28501 gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt gatcaaagct
    28561 tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt caatgcttgg
    28621 gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat ctttaaatct
    28681 ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa
    28741 taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat cactttcttt
    28801 aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt catcgtacct
    28861 gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga accatgcaat
    28921 gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac ggcttcttct
    28981 ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc ggataccggt
    29041 gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc tgccaggctt
    29101 ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga aaaaatcccc
    29161 gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt aaagagaata
    29221 ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc tgttactaaa
    29281 ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc ttctagtaga
    29341 tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt cattttttcg
    29401 acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa caaggatttt
    29461 ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt tgattcgttc
    29521 aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg
    29581 ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa gtttagcttc
    29641 taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg ctggtgcaaa
    29701 gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc ggttcaaata
    29761 agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat aagtaagccc
    29821 ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat aaagtgctac
    29881 atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca gttctgagat
    29941 caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc tggcgttagg
    30001 ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt tctcataaga
    30061 aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg actcccttaa
    30121 tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt cgataccagt
    30181 aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa taacacgttc
    30241 acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt attttacatg
    30301 ggattgcctg atcacttttc ctttaccgat ataatgaagg tagtcttcat acatcgtatg
    30361 gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa gtatccctgc
    30421 tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa ccaaataagc
    30481 ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg gtacacttgg
    30541 cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg taaaaatata
    30601 gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc
    30661 gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa
    30721 actagtcctt gacctgattt acttttttta atttgctaga gactttttca ttcagtacac
    30781 tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct tttgctgttt
    30841 gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg atcagtcgga
    30901 taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac cagccattat
    30961 acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct aaaacaacga
    31021 tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa tacgcacctt
    31081 ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga tcttctttta
    31141 caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac caaataaatg
    31201 tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta cgttcgaaaa
    31261 acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat tctctgaact
    31321 tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg gaaatagctt
    31381 gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt gttggcgtga
    31441 tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata ggagaaagct
    31501 ggttcgatcc gataaaggaa tttcggaaat cttcctctgt agaatgcgca tgatagacaa
    31561 ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt ccgtatgtat
    31621 tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata ccgacttccg
    31681 tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca agcatctttt
    31741 cactttcaaa atataataat accttcacct tacgtccccc ttcacttata tagtataaca
    31801 tagcctacaa actgtcactc aaacttaagc cctattttt
//
LOCUS       DAPBBR010000030        31333 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPBBR010000030 DAPBBR010000000
VERSION     DAPBBR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.030"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1..369
                     /locus_tag="RD488_001552"
     CDS             1..369
                     /locus_tag="RD488_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDT7657630.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="RD488_001553"
     CDS             549..1490
                     /locus_tag="RD488_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDT7657631.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="RD488_001554"
     CDS             1559..2290
                     /locus_tag="RD488_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HDT7657632.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="RD488_001555"
     CDS             2434..4614
                     /locus_tag="RD488_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDT7657633.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="RD488_001556"
     CDS             4634..5116
                     /locus_tag="RD488_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDT7657634.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="RD488_001557"
     CDS             5132..5893
                     /locus_tag="RD488_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7657635.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="RD488_001558"
     CDS             6024..7358
                     /locus_tag="RD488_001558"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDT7657636.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="RD488_001559"
     CDS             7665..8150
                     /locus_tag="RD488_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HDT7657637.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="RD488_001560"
     CDS             8143..8826
                     /locus_tag="RD488_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDT7657638.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="RD488_001561"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="RD488_001561"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDT7657639.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="RD488_001562"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="RD488_001562"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HDT7657640.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /locus_tag="RD488_001563"
     CDS             12442..13071
                     /locus_tag="RD488_001563"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDT7657641.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="RD488_001564"
     CDS             13123..13455
                     /locus_tag="RD488_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7657642.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="RD488_001565"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="RD488_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDT7657643.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="RD488_001566"
     CDS             14281..15654
                     /locus_tag="RD488_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7657644.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="RD488_001567"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="RD488_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDT7657645.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="RD488_001568"
     CDS             16709..17149
                     /locus_tag="RD488_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDT7657646.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="RD488_001569"
     CDS             17293..17994
                     /locus_tag="RD488_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDT7657647.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="RD488_001570"
     CDS             17991..19112
                     /locus_tag="RD488_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDT7657648.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="RD488_001571"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="RD488_001571"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDT7657649.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="RD488_001572"
     CDS             20491..21399
                     /locus_tag="RD488_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDT7657650.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="RD488_001573"
     CDS             21434..21706
                     /locus_tag="RD488_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDT7657651.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="RD488_001574"
     CDS             21717..22763
                     /locus_tag="RD488_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDT7657652.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="RD488_001575"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="RD488_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDT7657653.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="RD488_001576"
     CDS             complement(25774..26460)
                     /locus_tag="RD488_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657654.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="RD488_001577"
     CDS             complement(26438..26932)
                     /locus_tag="RD488_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7657655.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="RD488_001578"
     CDS             complement(26952..28172)
                     /locus_tag="RD488_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7657656.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="RD488_001579"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="RD488_001579"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDT7657657.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(30248..>31333)
                     /locus_tag="RD488_001580"
     CDS             complement(30248..>31333)
                     /locus_tag="RD488_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7657658.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10430 a         5601 c         6715 g         8587 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aatattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 atacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gattttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gacgaggacg aaccgaagaa atagcaaggg tttgtttgaa aacagtgtaa
    30181 aaaataaacc atgtttacat ggatttgcca ccggtttgcc accggtggtt tttttcggtg
    30241 gcaaaaatca agaattcttt ctaagatttt ccatgatatc gaccgtttca tttctcatct
    30301 tatctgttac atgcgagtaa gtatccatcg taattgaaat tctgctgtgg cccaatcgtt
    30361 cagagatttc tttcattttt gcgccatttt cgagaagaag tgtagcatga gtatgtctga
    30421 gagaatggaa gttaaaagag agggagagtg cattcgatat cctcctagta ttccatttca
    30481 ctacacttgg cgtaactagc tcaccgtctt ccttcgtaca tactgcattt gaatcaatgt
    30541 agagctttcc atacttcatt cgattttcta attgttgttt cttatgtttt ttcagaattg
    30601 ctagcaaggt ttgtccaata aaaatcgttc gattggaact gcttgtcttt ggcgtaccat
    30661 atacccatgc gccgtcattc tttaccattt gtttctctac agtaattgtt ccatttgaaa
    30721 aatcgacatc atcccacgtc agaccacaaa cttcgccaac gcgcattccc gtataaaatc
    30781 caatattcaa aggaatatag aaaggatgtc cttcaggagt aatttctagc atatgatcaa
    30841 agtcctcaag agaaatgatt tttagatctt ttttagtcgt tggtcgtgct tcatattttg
    30901 gtatttttac atacagcata ggattttgct tgattaatcc ccaaggataa accgccatat
    30961 tcagcgcatt cttaaggaca gagtgagtaa tagtcattgt tttcttcgag taaccctttt
    31021 taaattcagc attgatgaaa ttttgtaaaa gagcagggga gagatccgta agttttttct
    31081 ttcctaaata accgtttata tgatttttga tggtaaatcg gtagttttca taggtattgt
    31141 attttagatt tagtttaacg tattcctcca tccaaaaatc aaggtattgt tttactcgag
    31201 tatccgtacc taaaaagtat tgtcctgttt cgtcaatatc tgataaaact tttcgtaaag
    31261 cagcttcggc ctctggtcgg gtgtctccgc caactttctc cacttttttt cttgagccat
    31321 catcattgat atc
//
LOCUS       DAPBBR010000031        30602 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPBBR010000031 DAPBBR010000000
VERSION     DAPBBR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.031"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(257..598)
                     /locus_tag="RD488_001581"
     CDS             complement(257..598)
                     /locus_tag="RD488_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7657659.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(598..828)
                     /locus_tag="RD488_001582"
     CDS             complement(598..828)
                     /locus_tag="RD488_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7657660.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1124..1462
                     /locus_tag="RD488_001583"
     CDS             1124..1462
                     /locus_tag="RD488_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657661.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTREDFAIVECEIVAIFVEEGILHDPTHINVDKWQPLIYKLREYTTANQSLSL
                     NFRFQEFKES"
     gene            complement(1667..2242)
                     /locus_tag="RD488_001584"
     CDS             complement(1667..2242)
                     /locus_tag="RD488_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HDT7657662.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDVSFARKIITQQMPELVMEKV"
     gene            complement(2607..3188)
                     /locus_tag="RD488_001585"
     CDS             complement(2607..3188)
                     /locus_tag="RD488_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7657663.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMVVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWIKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(3371..3997)
                     /locus_tag="RD488_001586"
     CDS             complement(3371..3997)
                     /locus_tag="RD488_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7657664.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFSLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4019..5347)
                     /locus_tag="RD488_001587"
     CDS             complement(4019..5347)
                     /locus_tag="RD488_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDT7657665.1"
                     /translation="MEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTCMYGGTCI
                     NIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFL
                     SNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEK
                     LVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFHL
                     GVSVDQVADQESTAAVTFTENGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRG
                     AIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPY
                     SVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDL
                     ILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(5506..5907)
                     /locus_tag="RD488_001588"
     CDS             complement(5506..5907)
                     /locus_tag="RD488_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7657666.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5993..6199)
                     /locus_tag="RD488_001589"
     CDS             complement(5993..6199)
                     /locus_tag="RD488_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657667.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(6294..7796)
                     /locus_tag="RD488_001590"
     CDS             complement(6294..7796)
                     /locus_tag="RD488_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDT7657668.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7814..8269)
                     /gene="argR"
                     /locus_tag="RD488_001591"
     CDS             complement(7814..8269)
                     /gene="argR"
                     /locus_tag="RD488_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7657669.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(8367..8984)
                     /locus_tag="RD488_001592"
     CDS             complement(8367..8984)
                     /locus_tag="RD488_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDT7657670.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            9205..10578
                     /locus_tag="RD488_001593"
     CDS             9205..10578
                     /locus_tag="RD488_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7657671.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10653..11765
                     /locus_tag="RD488_001594"
     CDS             10653..11765
                     /locus_tag="RD488_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDT7657672.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11837..13474)
                     /locus_tag="RD488_001595"
     CDS             complement(11837..13474)
                     /locus_tag="RD488_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDT7657673.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13642..14250)
                     /locus_tag="RD488_001596"
     CDS             complement(13642..14250)
                     /locus_tag="RD488_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7657674.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(14634..15785)
                     /gene="queG"
                     /locus_tag="RD488_001597"
     CDS             complement(14634..15785)
                     /gene="queG"
                     /locus_tag="RD488_001597"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDT7657675.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(15804..16556)
                     /locus_tag="RD488_001598"
     CDS             complement(15804..16556)
                     /locus_tag="RD488_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657676.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(16697..17647)
                     /locus_tag="RD488_001599"
     CDS             complement(16697..17647)
                     /locus_tag="RD488_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7657677.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(17648..18487)
                     /locus_tag="RD488_001600"
     CDS             complement(17648..18487)
                     /locus_tag="RD488_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7657678.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(18484..19230)
                     /locus_tag="RD488_001601"
     CDS             complement(18484..19230)
                     /locus_tag="RD488_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7657679.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            19468..20838
                     /locus_tag="RD488_001602"
     CDS             19468..20838
                     /locus_tag="RD488_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7657680.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(20893..21789)
                     /locus_tag="RD488_001603"
     CDS             complement(20893..21789)
                     /locus_tag="RD488_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7657681.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(21903..22073)
                     /locus_tag="RD488_001604"
     CDS             complement(21903..22073)
                     /locus_tag="RD488_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657682.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(22070..22747)
                     /locus_tag="RD488_001605"
     CDS             complement(22070..22747)
                     /locus_tag="RD488_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7657683.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(22838..23743)
                     /locus_tag="RD488_001606"
     CDS             complement(22838..23743)
                     /locus_tag="RD488_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7657684.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIEVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            23918..25372
                     /locus_tag="RD488_001607"
     CDS             23918..25372
                     /locus_tag="RD488_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7657685.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            25388..26419
                     /locus_tag="RD488_001608"
     CDS             25388..26419
                     /locus_tag="RD488_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7657686.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            26426..27613
                     /locus_tag="RD488_001609"
     CDS             26426..27613
                     /locus_tag="RD488_001609"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDT7657687.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            27769..29151
                     /locus_tag="RD488_001610"
     CDS             27769..29151
                     /locus_tag="RD488_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7657688.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            29123..29509
                     /locus_tag="RD488_001611"
     CDS             29123..29509
                     /locus_tag="RD488_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657689.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(29709..30377)
                     /locus_tag="RD488_001612"
     CDS             complement(29709..30377)
                     /locus_tag="RD488_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDT7657690.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         8610 a         6227 c         5557 g        10208 t
ORIGIN      
        1 tttctgttaa agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa
       61 gttttgtgac acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat
      121 gctatatatt ctttagttta agatacggaa attaatccca tcgaccacac tagtagaatg
      181 aacgacattt acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag
      241 agtttactta caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt
      301 gcaatggtaa gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt
      361 gtgtaataat tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta
      421 aattctttat agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt
      481 cataacgaga gacgactagt cctggtcgtc ttttttgaat ttcttttcct actgagggat
      541 caaaatcaat ccatacaata tcaccttttt taggaatata aattctttct tctgacacta
      601 taaaatttct ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc
      661 ctcttcccca ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc
      721 agaatacaca acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa
      781 agttaccact acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc
      841 cttaataaaa gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct
      901 agaaaattgt tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca
      961 gttcattttt tctttaaata aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa
     1021 gctacccaaa tactatagct aactccccgc taccttcaat cttgcagata aaacgctttg
     1081 gaaaaaaatc gagaaaatcg caaagacgac aggccatcct atcatgcctg attataaaca
     1141 aaaagctggc tattcctttt gctctgacaa atttcaattg ggaaagttca cgaaactagc
     1201 aggtgaagaa gtttcaactg ttcggattaa agaatgcccg attcaaatag aaacgttggt
     1261 tcaacgaatt tcaactagag aagactttgc tattgtagaa tgtgagatcg tagctatttt
     1321 tgtagaagaa gggattttac atgatccaac tcatatcaat gtggataaat ggcaacctct
     1381 tatctataaa ctcagagaat atacaactgc caaccagtcg ttaagtttga attttagatt
     1441 ccaagaattc aaagagtcat aatgataaac atcattaggt ataaataaaa aagactcgca
     1501 gaacgagtaa aaaacaaata gaagctatac cttagaaagg tcgactgtga ctctatagat
     1561 gcagtatatg cagcttatga gcatttcttc tgttctcttt gtttttggga tctgtgctga
     1621 agtctttttc gttttttgcc gctctttctt tgaaaaatcg attatgttat accttctcca
     1681 ttactaattc aggcatctgt tgagtaatga tttttcgcgc aaaagaaaca tctgttaccc
     1741 aaggttcgat ttgttcttca gtcaagacaa gcggcattcg gtcatggatt ggtgcgactg
     1801 tgcggttagg ttcagtagtc attatgattg attctgccat tttttcatcc tgatggctac
     1861 gataaaaacc gccaatatac actatttttt ccttatttga aaacataaat ttgtcttttt
     1921 cttcattcca ctcataaaag ccactcattg ggaaaacaca acgattttgc aaaaatggtt
     1981 gatgaaaggt ctttttttct tctactgtct ctgcacgggc attaatcatc aattgtcctt
     2041 ttttaaatcc ggtaaatccc cacttcatga tttccggagt gaggatgttt tcttcctctt
     2101 ttcttaacgt cacaacaaga tttgacggaa aaacttctcc agctgctaat tctgctgcct
     2161 gctccggttg tttcgtctgg gcttctcgat aataattctg aaggagctct gactctagat
     2221 caaaaaaata acgaccacac atcctaatcc ctcccaatct ttttttctat catacactgc
     2281 aacaagaagt ccgtaccaac aaaacgcttt caatttgtgt agaactaaaa aagttgtgac
     2341 aagtgacaaa ctctccagtg aatggtattc tcctgccaac tcctcggtca caagtcacaa
     2401 tattcaacaa acatgagaag ctgctttttg aaattgttcc ttgtgactcg gagtgaaacg
     2461 gcaggcttac gacctctggg taaacggtgt tccagaagta gcttcttcga aaaataagcc
     2521 gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt cttgaagctg
     2581 accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa caatctttct
     2641 ttgatcaatt gaaaattttg tctaagtagt gatagatcct gtgtgacttt caacaataag
     2701 atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc ttcatcggac
     2761 agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgatcca ttgattgact
     2821 aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat aatcaaatta
     2881 cctacaggac agccatgata agtgatctgt gtctcatgat cagcaaaaat ccagtccaac
     2941 atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc gaacaattct
     3001 gtctgccaca cgaccatatg cgcatggatc accgctagac aaacttcttt ttttgaagaa
     3061 aagtaataat aaaattgccc tttccccgtc tcagaagctg ctagaatatc tcggattgac
     3121 gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat cttttccttt
     3181 gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca ataaattcat
     3241 cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac
     3301 tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga ggacaaaagc
     3361 aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact tgatctgcaa
     3421 taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg accaggagca ccaattgcat
     3481 ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg gaatcgctac
     3541 acaagtttcc gttcattcca ccaagaatca ctgtgtcgat tccatttttt ctcaattgga
     3601 gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgata atcgtatttt
     3661 catccaaata tggtttcaat tcttcgatga aatcagctcc tgaaccttct tcaactgatt
     3721 catattgact tttcctagca aacatctgtt gctcaagcat catatgttct cctgcaccgc
     3781 caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag agtttgtatc
     3841 ctttttcttt tgcttgtttc accatttcga tcatgttttc gatcgtattg tatttttcta
     3901 agatatcttt tgtcaaacta aagccaccgc ctgctggttt caagaactcg acttgcgggt
     3961 cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca ttcgttattt
     4021 attttaatac atcatttaaa gcttcactca ttgttggatg agaatagatt tgatctctca
     4081 ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg acttcatgag
     4141 aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg actaaaactt
     4201 tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt gtcatatact
     4261 tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa cctacattgg
     4321 ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc gttgttcgtt
     4381 tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag atataagtga
     4441 actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt
     4501 attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt tctaatccaa
     4561 gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct tggattgtta
     4621 cttcttggcc attttctgta aaggtgacgg cagctgttga ttcttggtct gctacttgat
     4681 ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct aaaatcattt
     4741 gcgcgatatc ttcatcttca cgaggaagaa attcaggatg ggcatcaaga acgacaactt
     4801 tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca gccccgatga
     4861 tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca atcaagtagc
     4921 gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta ttgatgaaaa
     4981 tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt tgatggttag
     5041 aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg atcatatgat
     5101 aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc tctgtaaagt
     5161 cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg atgttgatac
     5221 atgttccgcc atacatacat gttgactttt caacgactaa aaccgattcg ccttttgaag
     5281 ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata ttttgatatt
     5341 tttccatcct ttttccctcg cttctttttt tacctaccga ttggtacaaa aatatgataa
     5401 ccgataattg tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa
     5461 gcggtccttt cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac
     5521 ttctacatcg atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc
     5581 tgcaattttt tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc
     5641 gatctgatag ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc
     5701 tgctgtcatt cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata
     5761 acctgctgca aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat
     5821 tttcatatgc atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat
     5881 cattgctgtt tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact
     5941 tggctataat tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga
     6001 ataccagaat gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca
     6061 acagcgtcat atttgttcca aaataaatag caatcttttc tacataatct tttatatgat
     6121 tgattttaag atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa
     6181 taaccatatt cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt
     6241 aaccatacca ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct
     6301 gctgttaatg attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc
     6361 aacttgttct ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag
     6421 cttaaacgga tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct
     6481 tcttcatttt ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct
     6541 tctaatatct tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct
     6601 tgtacttcta cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt
     6661 tttaattctg gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa
     6721 tagttttcct tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca
     6781 agacggttaa gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact
     6841 tggatgcctc ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc
     6901 acgattcttg ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta
     6961 tttcgattga tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg
     7021 aaaatgatcc caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct
     7081 tctttattat caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg
     7141 gaacctgttg aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca
     7201 ccatttccgg catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca
     7261 atcccctttt taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt
     7321 tctacgcttc cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata
     7381 tcttcttttt ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga
     7441 agatggctag cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac
     7501 ataaacatag caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc
     7561 agactttgga tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc
     7621 ccaatcgtcc attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct
     7681 agtccccagc cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact
     7741 ggtaatgcga ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa
     7801 aagtcctcct catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt
     7861 cttctgagcg gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag
     7921 ggtaagccac ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata
     7981 cgataaccat gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca
     8041 aacgttcttc atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt
     8101 tttcattttg actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag
     8161 tcacatcggc gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt
     8221 gttctgtaat gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct
     8281 ctcaatgttg attatagcaa aagataagta atatttcttc atattttggt attttttact
     8341 tttatttttt gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc
     8401 ttcatttttt caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta
     8461 gaagctcttt catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt
     8521 tcttcggcat agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg
     8581 aatactactt gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt
     8641 gctatcgctt ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct
     8701 tttttcatca ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga
     8761 tagacagtat acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt
     8821 gcatagctga ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg
     8881 ccgatccctc tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt
     8941 ttcatactat agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga
     9001 aattccattt agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga
     9061 cactattttt cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt
     9121 tcggcgtgtc gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta
     9181 cgaaattttt tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca
     9241 gtaattgcaa cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta
     9301 actttcccaa ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca
     9361 acgatttatc ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat
     9421 tttagtctca aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc
     9481 gatttcttct ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg
     9541 acaggtatcg ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga
     9601 cgaggcgcga tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc
     9661 acttatggag gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg
     9721 cccgttttga ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa
     9781 aaaagtggtt atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt
     9841 ctaacatttt tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt
     9901 attggctggt tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg
     9961 tctattcttt caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt
    10021 ttattacttg gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt
    10081 ccttttgtcg ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct
    10141 ttttccggga aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt
    10201 ctttctttga ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta
    10261 ttgattgctt gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg
    10321 accaccggaa tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat
    10381 accttgcagc agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac
    10441 gtccagcatc atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca
    10501 ttaggcgtct tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc
    10561 tttgctaaaa aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt
    10621 gaaaatggtt gtttgtaaaa ggaggctttt ctatggaaaa aattgccatt atcggtggcg
    10681 ggatcattgg tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat
    10741 ttgatgaagg gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt
    10801 cgaaacgcag aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta
    10861 aacttataaa agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc
    10921 ttcgacctga aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag
    10981 cgccagaaat tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt
    11041 tattgaaacc agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat
    11101 atttagaaca tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag
    11161 tcactttgca taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag
    11221 ctgatcgtgt aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct
    11281 atgctgcaga tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga
    11341 tgagtcaaga ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg
    11401 atggaaagat ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta
    11461 ctagcgaagc ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc
    11521 agataaaaaa ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt
    11581 ccccattttt cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct
    11641 cttctggctt gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg
    11701 gtcattggcc tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat
    11761 catagaaaaa cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct
    11821 tgaaaaagct gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt
    11881 catctggcaa gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc
    11941 gttgtttcac cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag
    12001 gtaaatagtg gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga
    12061 ttctttcaac gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag
    12121 tattcaggac atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt
    12181 cttccctaag aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta
    12241 gctgtctttt tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa
    12301 aagacgctgc taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca
    12361 tgatccaaaa aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat
    12421 aacgtgattt gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt
    12481 ctcctttact tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg
    12541 gatcatcaga cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa
    12601 aaccattttt tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt
    12661 ccgtatgttt tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca
    12721 tcgtataggt ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc
    12781 cattgcgatt tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt
    12841 aacgtaatcc tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg
    12901 gaaatgtttc atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg
    12961 aaacagactt ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat
    13021 aagaatacaa attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt
    13081 cttcagatag gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca
    13141 cagcttctct taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc
    13201 gccgagcact tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat
    13261 cagctggtaa atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg
    13321 gactcccttt tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac
    13381 cgtaaaatgt cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga
    13441 tttcgtttaa ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa
    13501 aaacgttttc tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag
    13561 caaacgagtt atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt
    13621 catcattttc cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc
    13681 atcccatgaa ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc
    13741 tgaatagtcg ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt
    13801 agtagctgtg tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga
    13861 agttggcgct gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc
    13921 aacgtatgta tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt
    13981 gttttctgtt gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata
    14041 aatgcggttg atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc
    14101 tcctgcaaat ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc
    14161 atcagcgtga gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt
    14221 acctaaaaca attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat
    14281 tctttcgacg ctattaactt tatcatttag aaatatttca taggtaaaag aaacatgaca
    14341 tttaatgaca aaataacgaa ttatttaata tttgtaacat ttaaacaaat atttttttga
    14401 tacaaaacca taaaagcctt gttgtataag caaagtaatc gtttttctat gtttttttat
    14461 ttttgaatga aaaacgcaga ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa
    14521 aaaaattttt gatttttatc aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag
    14581 taattgttac aacaattact ggacaaaaac tttgaataat gttaactatt tttttatttt
    14641 aactttctcc gcaataattt ctgggcatgt tccaattcgt ttataacgac ttcttctgtt
    14701 tctttagcta atatttcatc taatacatca agccattttt ccggttcttt tgttcctaga
    14761 cgtccaatag cccaagctgc tgttcctctg atgacagggc ggacatctgt taaacattct
    14821 gaaatctcag gcaatgccgt tcgatcacct agattagcta aagcaatcaa tgcgtttctc
    14881 tgcaaaggtt tcttcccacg ccatgaacca gctaaatgcc caaattgctg tttgaagtct
    14941 ttattagaca tcgaaagcat tggctttaat tttggatata tttcgtctac ttttggttcc
    15001 atctcttcat gaaaatgaaa atcttttcct tgattgtaag ggcagactaa ctggcagata
    15061 tcacatccat aaatgacatt tcgcattttt ttacgatatt cttccggcat catccctttt
    15121 gtctgagttt gataagacaa acatcgctgg gcattcattc ttccgtcacc aagcaatgct
    15181 tttgtcggac aagcagtcac gcagcgcata cagtcaccgc aaccaaattc tcctggttta
    15241 tcaggctcaa atacaatatt agtaacgatc tcaccaagat agacaaatga accgaactct
    15301 tcagtgatca acaatccgtt tcgtccaata aatcctaaac cagctcgctg tgctacagcg
    15361 acatcgatca gttctccagt atctacttgc ggagctagac gccattcctc ttctttttgc
    15421 catttttctg ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc tctgagtata
    15481 tcatggtaat cgatccccca agaagcacga gcaaactgcc cgcgtttttc atccctaggc
    15541 acttcttcat ggatcctagt aggatacgca agtgcaatgg aaatgatcga tttcggctga
    15601 tcaaatgtca tttctggata aagacgctca tcgatatttg gatgttcaaa gccagaagta
    15661 tggccagctg ctttttgttc ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg
    15721 gtgaacccga ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc ttcttttaat
    15781 gtcatggtct tcctcgcttg ctgttaacgg ctgtataacc cataatatag tttttctttt
    15841 ttcagctgga caaactggat ctgctgatcg gcaatcttct tttcttccat ccattttttt
    15901 cttgcagcaa atacttccca ataatttgtt gaaattaatt ttcttttgtt atctaatgca
    15961 ttaaaaaaat tcaatgaaac tggttttgta cttaacagtt catggagcct tacctcttcc
    16021 catggcgaaa actcagacag atcgcgggaa tacaatactt cttcatagag atttttttgc
    16081 tgtgtgtacg tgaatgtttg cgggattttc ccaggcctag caatttctac tagacgatta
    16141 taaaacatat tcattaattt gctgttggca ataaattgac ttttataata ggccgactgg
    16201 atctttttga ttactccttc tgctttgatg actgaaaata atgcaggcca tgctttgacg
    16261 gttatttcgt cgttttgttt aactaatacg ccaggtgtga agccgactgg agaaaggaac
    16321 acaaaataac cgataccggt attttcatct aaaggctgaa attcatcaaa caaccatttg
    16381 cctatgtaca gctcttcatc tggttctgtt gtctcatttt gatttgctat gaataattta
    16441 gctaattctg cttcaagaaa ttgaaggtct tgatccttgt cggtattttc ctgctggctg
    16501 atcaatcgaa agacttcttc tttaatcgta tatttatctt tacgtgtaaa attcatagcc
    16561 acaccttcct tccttactct aactataacg gaatttcttc aaaaaaggta tctgtacgac
    16621 gaaaaacagc ataatttttt ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag
    16681 ctagaccttg cacttttcag ctttcttttg tttgtgacaa accttcatgg atcgtttcaa
    16741 tattccattt catcatctga tagtaagaat ctccttgttc tccttctttt gctatggaat
    16801 cagtgaacag tttatcatag attttcaaac ccgtttcttt tgctacccgt tccatgcttc
    16861 ttgagtctac actggtttcc acgaataaaa ccggtacttc ttttgctctt atctgatcaa
    16921 tgatcgcttt catttgatca ggcgtacctt gactttctgt attgatctcc catatataag
    16981 ctgctggcaa atcatatgct cgtgaaaaat acttgaatgc cccttcactt gttactaata
    17041 attttttgtt ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct aattctttta
    17101 gtttttccac atatgcttct gcattttttt tatagagtgt cgcattttct gcatcttttt
    17161 cagagaatat acgtgcgatt tcctccacat attttattcc gttagatagg tctagccaag
    17221 catggggatc tgcttttgta tgttcttcac cgctagttaa ataaagaggt tctacatttt
    17281 tgctaactgc aaaataatct tttccttctt cttttttagc cgtttccatc aagttatcga
    17341 accagctgtt acctgtttca agattcaaac cgttgtataa aataacatct gcatcgcttg
    17401 cctttttgat gtcttctggt agtacttcat attcatgcgg atctgttccg actggtacga
    17461 tactgtggat atctatttga tctgttccga cctcttttgc catgtccgcc aagatcgaat
    17521 tggtagccac gactgacaac ttttctttac ttccttcatc cgcttggtca gaagcctgct
    17581 ttccgcaacc ggctaatacc aagaaactaa ctgccaagat taaaaagagt gatttttttg
    17641 ttttcatcta tctgcttcct ttctgaaata aaattccttt tgttggagaa aataaaaaag
    17701 caaggataaa aaatgcggta catgctaaca cgatcgtagc tcctgatggc caattgtaac
    17761 tataactgaa aaacacaccg acaactgcac ttagcatacc gattcctgca gctgtaatga
    17821 tcattttcag taaatggttc gttagcaagt aagccgtggc ggctggtgtg atcaacatgg
    17881 caatcaccaa gattgttcct actgtctgta aactgactac agccactaat gtcaaaaaga
    17941 acatcaaaag ataatggatc agcgatgtgt tcagcccata agcttttgcc attgtcggat
    18001 cgaatgatgt gatcttcaat tctttataaa agaaaaagac aaatatcaag acgattccac
    18061 taacgagtgc tgtcagcaac aaatcgcttt ccctaacagc taagacattc ccaaataaaa
    18121 tatgatacaa atctgtcgca ctctgggcat atgaaatcaa gataatccct aatgcaaaaa
    18181 aggagctaaa gacaattcca atcgctgtat catttttcaa tcggctccgc tgagtcacga
    18241 aaccaatcac tgctgctgtt agcatcccaa aagcagtggc tccaaagatg taactaaaac
    18301 caaacatata agaaatggct acacctggaa gaactgcgtg agagatagcg tctcccatca
    18361 aagacatccc tcgtaaaata ataaaagaac cgatgactcc agaagcaagt cctacaagca
    18421 tggaagtgac caaagcgtat tgcaggaatt gataattcat taatccatca ataaaggatt
    18481 ggatcatttt ttctctcctc cttttactaa atgtctgatg atctcaccat aggccaattg
    18541 aaggttcttc gatgtaaaga cttcttgtac tggaccggaa gcgatcagct gtttatttaa
    18601 aagaataacc tcatcgaaat attcttctac tttatgaaga tcatgatgga cgatcaaaat
    18661 cgtttttcct gaattcttca attcctgcaa gatgtcaaag atctttcgtt cacttaacgc
    18721 atcaatccct acgaatggtt catctaaaaa gatccattct gctccttggg ctagagctct
    18781 tgcaataaaa actctctgaa gctgtccacc cgatagttcg ctgatctgtc ttttggcata
    18841 ttcttccatc cctacttttt tcaaagcttg tcttgcacgt tctttttctt ttttcccagg
    18901 tctttgtcca attcgtaaag atggatatgt tcctaaaagt acaacgccta atacatcaat
    18961 tggaaaggaa agatccaatt cacttcgctg ttccacgtag gctatttttt tacggactga
    19021 gtttaccggc tgtccagaaa aggtgacttt accagtagta gctggtatca actctagcaa
    19081 agatttcata aatgttgatt ttcctgcacc gtttggtccg ataataccgg taattttttg
    19141 tggatttatc gtcaagttga tagttttcaa aacagttttc ccttgataag cggctgaaag
    19201 gtcttgaatt acaatggccg tacgttccaa atcttacact cctttttagg tttacctaac
    19261 tttttattta aatatagttt aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa
    19321 gtttttttcg aattttcctc gcattttatg aaaattttct gtagaatcac atcaagagtt
    19381 caataaggct aacctaataa tgaaaaacat gtgttgaaac gtttgattat tttttcttgt
    19441 tgactcaaca acgaaaggag tttttgtatg gaagaagaaa agttaactcg aagtcttagt
    19501 gcccgtcata tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt
    19561 gcctcctcaa ccatacgttg gacagggccc tcagtgatgg gagcctatgc gattgcagga
    19621 ttctttttgt atttgattat gcgtgcttta ggcgaaatgc tttacgttga tccttcgact
    19681 ggttcttttg caaattacgc gagcgagtac atccatcctg tggctggcta cttgaccgct
    19741 tggagtaata tttttcaata tattgtcgta ggaataagtg aagtgattgc tgtaggatct
    19801 tatatgaatt attggtggcc tgatttgccg gcaattattc ccggaatcat tgtcgtcttg
    19861 tttcttatgc tggcaaatct tatttctgtc aaggcgtttg gcgaattaga attttggttt
    19921 tcgatcatca aagtcataac gatcattttg atgatcattg caggtcttgg ggtaatctta
    19981 tttggatttg gtaatcatgg tcaggcagta gggatttcaa atctttggaa aaatggtgga
    20041 ttcttcactg gaggcgtcaa aggatttttc tttgcattat cgatcgttgt tgcttcctat
    20101 caaggaatcg aactgatcgg aatgactgct ggtgaagcag agaatcctaa aaagacgatc
    20161 attgaagctg tccagtccac tatcggtcga atcttgattt tttatattgg tgctattttt
    20221 atcattgtga gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa
    20281 actttttcta aagtcggcat tacatttgct gcaggactga ttaattttgt cgtgattaca
    20341 gcggcattat caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt
    20401 gccataaatg gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt
    20461 tatcctgtcg tagcaatctc aggtggaatc ttaattggtc tgatcttaaa ttatcttcta
    20521 ccaatgttca tcaaccagtc agaaaatatt ttcgttttcg tatacagctc aagtattttg
    20581 cctggtatgg ttccttgggt agtgattttg atcagcgaga ttcgcttcaa aaagaagcac
    20641 gcagataaaa tgcatgatca tccttttaaa atgccactat ctccttatac gaattatgtg
    20701 acacttgctt ttttagctat cgtattgatt ttcatgttta tcaatcctga aacgagaatc
    20761 tcattgatta ttggactcgt tttcttgctt tacatgacga tccattactt tgtacgcgaa
    20821 aaaagaaccg gaaaataaaa aaagaacgaa gcttcacctt agtggaagct tcgttctttt
    20881 ttattgcttt tatcaattca attttagcgt ctcaccggga gtcaggaaat aattctccat
    20941 gctcatccca ttcagcgaca agatcgtttc tactggtacg ccagttcgtt cggctatttg
    21001 atttggacct tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt
    21061 attagtttca gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc
    21121 taccgactct gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc
    21181 ttgaagagag gcgctagtct gcaaataaat atcggaaatc ttagcgacat gattcgtata
    21241 attagccgat aattgattga tcaaagtatc taagtctaca ccgtctttat tttctgctgc
    21301 ctgatacgct gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc
    21361 tttttggtta gcaactgctg ataaaccagc tattccctct tgatttccct gaatttctgt
    21421 ctggtattct tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat aatcatttac
    21481 gattgcttga agttgctctg gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc
    21541 ttttgtttta gttgatgact cacttgtttg tttcgtctct gttttctttg tcgttgtttc
    21601 cgttatggtc gtacttttcg cttctgacga attttttcca tgaaaatata gacccgcaac
    21661 tcctcctgct atgatcaaaa acacggcaac tgctgcccca atcatgatca tccgcttacg
    21721 agctgcctgt ttttgctgtc ttcttcgggt catccgaaca ttttctcccc actcattttc
    21781 atcatacatt tttttcacca ccaattttta tgtataatag cgttatcaaa cgcttcatat
    21841 tcttattgta gcaaataatt gtcgctgtgc acatttttat ctttgttatt tataagaaaa
    21901 tttcaccagt tgagatgatt ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt
    21961 cgttcgtcta tctcagccat cagtttcttt atttcatata agagcgcacg gtcttgatat
    22021 tctgattttt cgcttaattc atctaattgt tggatcagcc aatcatttgt cataatgaag
    22081 ttcctttcat ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt gcctcagtca
    22141 gtgcttctac gatatatgct tgtttttcag attcttcttc ctgcattttc tgattttcct
    22201 gtactctttg aataaaccag tcaatccgct gagtcagcga tggtttgcct tccaatgaga
    22261 gatactgctg ataagcaatt agcttctccc aacgtttttc ctgggataaa tacataaatt
    22321 gtgctaaaac gaatggcgga agataggtca tatggaattt atttgcgatt cgctgatacg
    22381 gcctcaaaaa ttcggaaatc gtatattctt cttttcctcc agcttggtat tctttttccg
    22441 ccacacctgt tgtcaatacg attcctagtt ctttcccttt taatacatgt gctgctcgtt
    22501 ccaagacatt atcttgccaa atttttaaat gagcaggaga actataccag taaaacggaa
    22561 actggaaaat gatccgatca tgctgggcca agagctgtag ttcagtctct atatctattt
    22621 ttccgtctgg ataacttgat tccaaatgat gccaagtagc tggtaaacca gcagaagctt
    22681 ctttgaaaaa ttgctgattt aaagattctt cgatcgttgg atggctaatg atgataagtg
    22741 tacgcatccc ttttcctcct ttttagtctt cgctttacag tgtagcataa ccgccacaag
    22801 tttcttttgc cgatgcttgt cattttaacc agactaatca ggttgtccaa gaaactgcgg
    22861 tttgtttttc caactgtttt ttcaaggtat ccaaagcaat attcttaaaa ttttcgtttt
    22921 tcatacgttt acgatagttc gtagccgttt ctccggtact ctttttgaac attcggctaa
    22981 atacgactag actattgaac cctacttgat aggcaatact ttccacggat tcatccgtca
    23041 gagaaagaag aaacgcccct cgattgatcc gtacctcgat caaatattcc ttgatactgg
    23101 tgcccatatg atttttgaat actcgcgaca aatggctccg attgaccgct aaatgctggg
    23161 cgatttcctc aacagacaat ttttcagcat aatgtgcctc gatgtatttg actgtttcaa
    23221 cagctaaaga ggaatgaacc ttttgtacac ctccgctgac ctttccgcca tcttttaaaa
    23281 ggactgataa aaaacggtag gttaatgctg ttaactgtaa ttcattttcc aaggtttctt
    23341 ccgtatcttt catgcattct aaaataatgt cgatatattt ttgtatgtca gaagagacca
    23401 tcgtgtattg gtcttctctg aaaagcgact gccgaatgat ttcttctgca gcactcccac
    23461 caaatgaaag ccagcaatac atccacggat cttctccatc tgataagtaa aacgtcgagt
    23521 ctcctggacg aatcaagaac agatcacctt ttttcaattg gaattgttga tttttcacat
    23581 gataagatcc tttgccttcc atcacgacat gcaggatgta atcattgcga atagcaggac
    23641 caaaagaatg aaacggcatc gttttagaga aaccacaaaa atcaaaatac aattcttttt
    23701 ctacttgttg atgttccttt tttaaaaaaa tcgattgctc cacgtctatc cctccttact
    23761 cctttagtat aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag
    23821 cgatttcttg ttaagtttaa gtcattaaaa gatctttgtt attcgttgta accggtttac
    23881 ttagtattat atattgaaca ggagaggaat acagattatg aaaagcaaaa tgatccaacg
    23941 tgtgtcctac gctttaggcg cttttggaca cgacacattc tatgttacat taagcactta
    24001 ttttatggta ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa
    24061 aatgattgct acagttacaa gcttagttgt aggtatccgc ttagttgaaa ttatttttga
    24121 tcctttgatt ggtggcatca tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg
    24181 gttagttatc ggcggcgttg ttagttccgt actcttggta gcaatcttta ccaatttctt
    24241 tggcttagct actcataata cgactttatt tatcatatta tttgcaatcg ttttcatctt
    24301 attggatagt ttttattcat ttaaggatat cgctttttgg tcaatgattc cagctttgag
    24361 tacggaaaca aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct cttctctagg
    24421 tgcaaatggt actactctag tcgttgtccc tatcgttact ttctttacct atcttgttac
    24481 tcataaacat attgaaggcg cttcaggctg gttctggttc ggtgtgattg ctgctgttat
    24541 ttcaggcggt actgcgatta tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg
    24601 tcagcaaaat gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca
    24661 gttgatgtgg cttgcccttg cttatatcgc ttatgcgatt gccaatgtag caacaactgc
    24721 cgtattattc tacttcttca aatatgtact tggccaacca actgaatttt ggatcgttgg
    24781 tctagttgct gccttacttg gtttagtagc tgttccacta ttcccaatgc ttacacgcgt
    24841 catctctcgt cgctacgttt accttggagg gatcgcaatg atgatttctt cttacttttt
    24901 ctttacgatc gcaggttcaa gtttgccaat cgttatcatc gggctagtat tgttctactt
    24961 ccctcaacaa ttgattttct tatccgcttt gatgacgatc acagactctg ttgaatatgg
    25021 tcaatggaaa aatggtatcc gtaacgaagc tgttactcta tcaattcgcc ctttactaga
    25081 taaaatcgct ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg cttctgggat
    25141 gactggtaat gctactgctg ctgatatcac tgctcatggc gtaacgactt tcaaagctta
    25201 tgcattctat gctcctgctg ctttgatgat tttctccgct attatttttg cttggaagat
    25261 tacattgaca gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca aattggctcc
    25321 agctgataca atggaagatg aacttcacga tgcagtagtt ccttcccatt aagaaaggat
    25381 cttgaaaatg aagattacag aaaaagattt tggccaaggt tatcacttga taaccttgga
    25441 gaacaaaaac aagctagcac tttctatctc tgatttaggt gctagaatcg tcagtttaaa
    25501 atcaaatgat cgagaattag ttttgggatt tgacaccgct gaagaatata tcgaaaaaga
    25561 tccgtatatc ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg gccgcttttc
    25621 tctcaatgga aaaacttacc aattagccac agatccaaaa actggacata atctgcatgg
    25681 tggtgctcct ggatttgaat taaaaaaatg gtcttatgtc attttgaatg gcgaaaatga
    25741 agcttctgtc atttttacta ctacaagtcc cgacggagaa catggttttc caggtacaat
    25801 ggatgtggaa atccgctata ctttgacaaa agataatatc tggcgagtga cctctcgcgg
    25861 caccagtgac caagatactt tattcaatcc gacaaatcat gtttacttca acttgacggg
    25921 agatgcttct cagtcaatcg atcaacatga gctttggctc aatagcgaag cttatgctcc
    25981 tttgcgaaca gatagtattc ctataggggt aaaagaaaat gctgcaggaa gtgctttcga
    26041 ttttcaaata cctaaaaaat tagcgtccgt ttttgctagt gatttggatc aaaaaaatct
    26101 tgttgacgga atcgatcatc catttttctt aaaagaaacc ggcttgggta aagaagccgc
    26161 tcgcttgact agccccgata aaagaatcca agtagatatt gctacagatg cttctagtgt
    26221 ggttattttc actgcaaatt tcggcacaga aacaccagaa atgcgcaacc gaaaactggc
    26281 acatcacggt ggcatcacat ttgagactca aacagctcca ggtgcagagc gcttctcagc
    26341 atttggttcg attcatttaa aagccggatc agtatttgaa acagtgacag aattcaaaat
    26401 caaaacaaga aaggaataac tcatcatgga aatcaaaaga agcttaaaca caaaatttgc
    26461 cgaaacattc ggacctaaaa aaactacaca atacttctca ccaggacgca tcaatttgat
    26521 tggtgaacac acagattaca atggaggcca tgtcttcccc gcttccatca cttatggaac
    26581 gcaaggtgta gcagcacctc gagacgataa taaaatatta gtttattcca caaactttga
    26641 cgatatcggt gtcattagtt ttactttaga tgagctagaa tatgataaaa aagcaaactg
    26701 ggcaaattac gtaaaaggaa tggtccttaa attaaaagaa gctggacact caatcgatca
    26761 tgggtttgag ttattagtgg aaggaacaat ccctaatggt gcaggacttt ccagtagcgc
    26821 ttcattagaa ttattagtag gtgttgtatt agaagatctg tttgatttaa aaacagatcg
    26881 cttggaacta gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg tcaattcagg
    26941 tatcatggat cagtttgcca tcggcttcgg tgagctagat catgcaatct tattagatac
    27001 aaatacgctg aaatacgaaa tggttccagt gaaactagat ggttatgcaa tcgtcatcat
    27061 gaatacgaat aagcggcggg aattggcaga ttcaaaatac aatgaacgcc gtagcgaatg
    27121 cgaagaagcc ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag gagacttaga
    27181 tgaagaagaa tttgaatcaa ctattgacca aatcggcgat gatacattga tacgcagagc
    27241 tcgccatgcc gtttctgaaa atcagcggac tttgaaggca aaagctgaat tagaagctgg
    27301 gaacttagaa gcatttggtc aactgttaaa tgattctcac cactctcttc gctatgatta
    27361 tgaagtaact gggatcgaat tagatacact agtagatgct gctcaaaaac aagaaggtgt
    27421 cttaggtgca cgaatgacag gagctggatt tggtggctgt gcgattgctc ttgtcaaaga
    27481 agaaaatata cctgccttca aaaacaatgt ctatgatgaa tacatgaaag ttgtcggcta
    27541 tgctccggaa ttttatgttg cacacattgg aaatgggaca acaaagatcg atccagaagc
    27601 tgttcatgtt tgataaaaaa atcaacgatc tcagctaaaa acaaatagat aaaaataacc
    27661 tctcagcaat ttccaaatgt gagccttttg ctcgtatttg aaaattgctg ttttttattg
    27721 acacggaaag agaacgtgtg ttctaattgt gttgaagagg tgattgttat gtgggcgaat
    27781 caaaatccgg tatttgttta tgaaaaagaa ccttcaagag atattttatg tattgactgc
    27841 aaatcttttt acgcctccgt agagtgcgtt gaaaaggatc ttgatcccct tacaactaaa
    27901 ttagtagtca tgtcctatcc gtccgattcg acagaaacac ggggtagcgg attaatcttg
    27961 gcttccagtc ctgcagcaaa aaaagcttac ggcatcacca atatcagccg tgccagagat
    28021 cttcccttcc cctatccaag tgatttatat attgttgccc caaggatggc ctattatatg
    28081 gaaaagaaca gagaaatcaa ttctatctat aaaaaatatg cagacgaagc gaaccatcat
    28141 gtctattccg tcgatgaaag cttccttgat gtaacaaata gcatggcact ctttggtaaa
    28201 acaaatgcgt acgacatggc taaactgatc cataaagatg tgtttgagca gaccggaatc
    28261 tacacgacta taggaattgg cgataacccg ctacttgcta aactagcctt agacaatggc
    28321 tcaaaagacg gaaagcaaat gtttgctgaa tggcgttatg aagatgtacc agaaaagtta
    28381 tggaaaatct cagatatcac tgacttttgg ggaatcggca aacgaacagc aaaacgtctg
    28441 aaacaaatgg gtatacattc tgtttatgat ttagctcacg cggattatta tcacttgaaa
    28501 agcaagctag gggtcatcgg tactcagctt tatgcccatg cttggggcat cgatcgaagt
    28561 tttttgggac aagaatatac accaaaatca aaaagtatcg gaaatagtca aatcctagat
    28621 agagattata caagacgaga agaaatcgag atcgttatca aagaaatggc cgaccaagtc
    28681 ggcactcgct tgagacgatc tgcagcaaaa acacaagtag tcagcttatg ggtaggatac
    28741 tctttaggct atcttgatcc aaatggcaag accgggtttc accagcaaat gaaaatcgaa
    28801 gcgacaaatg ctagcagaga tctagcagat gctttattga ccattttcca ccagcattac
    28861 cactaccagg atattcggcg tgtaggcgtg aactgttccg acctcgtata cgcgacaggt
    28921 ttacagctta acctttttga agatcctgaa aagcagataa atgaagcgaa agttgatttt
    28981 gttgtcgata cgattagaaa aaaatacggc tttcaatcaa tcatccatgc gcatagtctc
    29041 ttgcaaggag gacgcgccat cgcacgtagt tctctcgttg gcgggcatgc aggtggtatg
    29101 agtggattag aaggtggaaa agatgagacg gacagcaaaa aaattcattg actataacga
    29161 gtatcgagat cggccatttg gattaaaatg ggggactgct tttgcgatgg aagaactagt
    29221 caacggtatc aaaaaaaatg aagaagaagc acgcaaacag cctcttccta aacaacaaat
    29281 gacattgcaa gaaatcgata gtatactgac agaagccttt ttatctcgta aagcagtaat
    29341 cattcagctc aatttaaaag atgaatttgg aagactcttg gatgaggtcg aagggcactt
    29401 cattggtgaa gcctatgaag attactttat gattgaccat cagccgatat tgtgggaaga
    29461 cgtacggtat attgagttaa aggaaacaaa aaaatggttt gtgacatgag aggttgtgac
    29521 agaagtgatc aacttcaaaa aataagaaag gatttttcga aaattgcttc ttaaattttt
    29581 gtggaatttt ggcttatttt tcgaagaagc aacttctgga acaacgtata ttagatatca
    29641 gaggttgtga aaaagtcgct tagttttgag taacaagcca aggcgctgat ttcacaacct
    29701 ctgtctatct atccatctat tcggtaagat tcatgcatga cgtcttcttt atttagtatg
    29761 tagagccctt tttcttctga ccattcaaca taaatcagct gttttacatc tgcatagcct
    29821 tctttcttca agttctccat aagccatgct tcagtcaatt gattggactg aagcacttta
    29881 tgctgaattt gcccttcatc tacaagcagg atcgataaag ctttgtcttc atctgatttt
    29941 ttcaatacac tcatttgacc ggcattctct aggataacat gtttggcatt ttcaagaaaa
    30001 aagcattctt gctgtcttaa gattgctcgc aactgctcca tctcgatatg gttatttgtc
    30061 aactctgtca tgttgatgac gccgtctttg attagaacag atggctcgcc tttgacccaa
    30121 cgattgacct tttcattttt ttggacgata cgttcgatac cataaatcat tactgcccaa
    30181 agcgcaatgg caaataggac atgccctaca tggacattgt catcataggt tgattcttct
    30241 aagatcccac ctaaaacaag cgtatagact aaatcaaacg gtgtgatttc tgacatggat
    30301 ttcttcccaa gcaaacgtac cactaataat aaaccgatca acccgaacac cagtttcatt
    30361 gtaattgaaa aaatcatttt ttctccccct aactatctgt taattaaatt atatatgctt
    30421 tctcacgaac acgcatggaa tatacaagga agaaatgtat ccttttacta aaaaaaggac
    30481 tgtgacactg tagtgacccc caaaagttag acttttttgg agtggagaaa tccactcctt
    30541 ttttttatgc tctaaaatga tatttttaca caaccgttac ggttgtttta cgaaattgga
    30601 cg
//
LOCUS       DAPBBR010000032        29105 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPBBR010000032 DAPBBR010000000
VERSION     DAPBBR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.032"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1026)
                     /locus_tag="RD488_001613"
     CDS             complement(<1..1026)
                     /locus_tag="RD488_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7657691.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNT"
     gene            complement(1108..1797)
                     /locus_tag="RD488_001614"
     CDS             complement(1108..1797)
                     /locus_tag="RD488_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7657692.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVVGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1903..2271)
                     /gene="rplL"
                     /locus_tag="RD488_001615"
     CDS             complement(1903..2271)
                     /gene="rplL"
                     /locus_tag="RD488_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDT7657693.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2324..2827)
                     /locus_tag="RD488_001616"
     CDS             complement(2324..2827)
                     /locus_tag="RD488_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDT7657694.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3031..3158)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3237..3926)
                     /gene="rplA"
                     /locus_tag="RD488_001617"
     CDS             complement(3237..3926)
                     /gene="rplA"
                     /locus_tag="RD488_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDT7657695.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4030..4452)
                     /gene="rplK"
                     /locus_tag="RD488_001618"
     CDS             complement(4030..4452)
                     /gene="rplK"
                     /locus_tag="RD488_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDT7657696.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4795..5463
                     /gene="sdaAB"
                     /locus_tag="RD488_001619"
     CDS             4795..5463
                     /gene="sdaAB"
                     /locus_tag="RD488_001619"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDT7657697.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5476..6348
                     /gene="sdaAA"
                     /locus_tag="RD488_001620"
     CDS             5476..6348
                     /gene="sdaAA"
                     /locus_tag="RD488_001620"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDT7657698.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6439..7458)
                     /locus_tag="RD488_001621"
     CDS             complement(6439..7458)
                     /locus_tag="RD488_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7657699.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7631..8536)
                     /locus_tag="RD488_001622"
     CDS             complement(7631..8536)
                     /locus_tag="RD488_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7657700.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8595..9140)
                     /gene="nusG"
                     /locus_tag="RD488_001623"
     CDS             complement(8595..9140)
                     /gene="nusG"
                     /locus_tag="RD488_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDT7657701.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9241..9411)
                     /gene="secE"
                     /locus_tag="RD488_001624"
     CDS             complement(9241..9411)
                     /gene="secE"
                     /locus_tag="RD488_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDT7657702.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9435..9587)
                     /gene="rpmG"
                     /locus_tag="RD488_001625"
     CDS             complement(9435..9587)
                     /gene="rpmG"
                     /locus_tag="RD488_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7657703.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9749..10393
                     /locus_tag="RD488_001626"
     CDS             9749..10393
                     /locus_tag="RD488_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7657704.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10449..10952)
                     /locus_tag="RD488_001627"
     CDS             complement(10449..10952)
                     /locus_tag="RD488_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7657705.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10965..11011)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11549..12514
                     /locus_tag="RD488_001628"
     CDS             11549..12514
                     /locus_tag="RD488_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7657706.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12613..13785)
                     /locus_tag="RD488_001629"
     CDS             complement(12613..13785)
                     /locus_tag="RD488_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657707.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13772..14917)
                     /locus_tag="RD488_001630"
     CDS             complement(13772..14917)
                     /locus_tag="RD488_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657708.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14931..15863)
                     /locus_tag="RD488_001631"
     CDS             complement(14931..15863)
                     /locus_tag="RD488_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657709.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15980..17059
                     /locus_tag="RD488_001632"
     CDS             15980..17059
                     /locus_tag="RD488_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7657710.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17056..17685
                     /locus_tag="RD488_001633"
     CDS             17056..17685
                     /locus_tag="RD488_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7657711.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17795..18022)
                     /locus_tag="RD488_001634"
     CDS             complement(17795..18022)
                     /locus_tag="RD488_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7657712.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18125..20713)
                     /locus_tag="RD488_001635"
     CDS             complement(18125..20713)
                     /locus_tag="RD488_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDT7657713.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20733..21392)
                     /locus_tag="RD488_001636"
     CDS             complement(20733..21392)
                     /locus_tag="RD488_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7657714.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21441..21944)
                     /gene="trmL"
                     /locus_tag="RD488_001637"
     CDS             complement(21441..21944)
                     /gene="trmL"
                     /locus_tag="RD488_001637"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDT7657715.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22165..23031)
                     /locus_tag="RD488_001638"
     CDS             complement(22165..23031)
                     /locus_tag="RD488_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7657716.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23140..23781
                     /locus_tag="RD488_001639"
     CDS             23140..23781
                     /locus_tag="RD488_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDT7657717.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23843..25204)
                     /gene="mgtE"
                     /locus_tag="RD488_001640"
     CDS             complement(23843..25204)
                     /gene="mgtE"
                     /locus_tag="RD488_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDT7657718.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSHKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25222..26121)
                     /locus_tag="RD488_001641"
     CDS             complement(25222..26121)
                     /locus_tag="RD488_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7657719.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26123..26920)
                     /locus_tag="RD488_001642"
     CDS             complement(26123..26920)
                     /locus_tag="RD488_001642"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDT7657720.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26898..27602)
                     /locus_tag="RD488_001643"
     CDS             complement(26898..27602)
                     /locus_tag="RD488_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDT7657721.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27733..28308
                     /locus_tag="RD488_001644"
     CDS             27733..28308
                     /locus_tag="RD488_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HDT7657722.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28426..29103
                     /locus_tag="RD488_001645"
     CDS             28426..29103
                     /locus_tag="RD488_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7657723.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6169 c         5231 g         9142 t
ORIGIN      
        1 agtattattt cggttgcttg ctgcttcacc tagcccttgt actcgtgttt gattggcgac
       61 ttgaccaaat tgattcccga cgtctaataa aataatagct aaaagcaaaa tggccaaatg
      121 gcttccgcca accaataaag caataaagct tattgtttgc ataacaagtc ccatatacac
      181 gatttttctt tcagaataag aatctgccag tcgtcccacg ataggtgcag caactgctcc
      241 agacaaacca aaaatcgcta atatccctgc ttcgaatgtt ccccaattgt aggcgggact
      301 gctgatataa aaaatcaacg tagaccaaaa gatcgaaaat gttccaaaca tgaaaaatcc
      361 actgactgcc gcttctctta atagacgttg agaagcaact aaatgcggca aacttttaag
      421 tgaatcaagg tatgaaacag ctgtactact ttgctggaca gaacgcggca ttttccagta
      481 aagcagaagt gtaagaattc cgactgcaca taaagcaaat aaatagatca tccgccaaga
      541 aaaaagactg gcaacaatac cagataccgt ccgagaaagc aaaatcccca cgagtaaacc
      601 gctaagcaat gtacccatga ccttccctct tgcttttggt cccgctagta ccgcaccgta
      661 aggaatgatg atttgcggca cgatcgaaag taatcctatt aaaaaagaag cgcatgcaaa
      721 taacgtaaac gaaggcgcaa aaaaagcggc caacagagag acggcagata acgctaccat
      781 tcgaatgatc aattttggac gatccaccac gtcccctaaa ggaactaaaa acagtaaccc
      841 taacgcatag cctaattggg tcaacatcgt caatatcccg actgcacttg tgctaacaga
      901 taaactagct gctacttttg ttccaatcgg ctggatgtaa tacatattgg caacaacaac
      961 gccacaagtg attgataata gtaaaataag cgaagttgtt aaaggtgttt tttcattact
     1021 cttcattgat ttcccccatt tcctatctta gtttacaact tatggaaaag attggaaata
     1081 gaaaaataca actattcgcc acacttatta tttgtgcttt tgttttcctt gttttttctt
     1141 gcgatcttta taaatgaaga caactaaccc tactagcaca gtaacacttg caaccaacgt
     1201 gactgcagtt ttgttatatc cgtgaaacag agcttctcca ccacacgcat acaacacaga
     1261 cgaagggatg actccaacca cgatcgacaa tatgatttgc tgtagaggca atttcatcgc
     1321 atctgcagca aaattgacca tagaagatgg aataaccggt atcatatagc ctaacattac
     1381 acctattttt ggatgtttca tttgtcggat tgcttgcacc caatgattcg tttcggtttt
     1441 cttatctaaa aattttaagc gatgcataag gaaaattgca gtgatgttac caagagcatt
     1501 acccaaaatg ttgatgatcg cacctgtcag tggtccaaag ctcaaaccag caatgactcc
     1561 aactactgaa gtaggaatac ctggaacagc acacatcacc gctgtcaata cgatcaagag
     1621 tatcgatgca aaagtcccat gcgaacgaat atgtgcgagt agctctgcct tactcgctct
     1681 cggatttaaa aataattgga tgtctgtctg atattctaaa tacaaccgat agcccactac
     1741 cagtatcaga atgattccca acgagatcaa catcaatcgg attattttct ttttcatatt
     1801 tcctcctgaa aaaaatctat attcattaaa taatagttta acataaaaac aaaaaagcac
     1861 cgaaatccaa cataggatct cagtgctttt aaatagtaaa aattatttaa cagttacaga
     1921 tgcgccaact tcttcaagtt tagctttcaa ttcttcagct tcttctttag atacgccttc
     1981 tttaactggt gcaggagcgc catcaactac agctttagct tctttcaagc ctaaaccagt
     2041 tgcttcacga actgctttga taactttaac tttttggtct ccagctgcag ttaattctac
     2101 agtgaattct gtttgttctt cagcagcagc agcgccacca gcagcagcta cagctacagg
     2161 agcagcagca gatacgccaa attcttcttc aatagcttta actaggtcgt taagttctag
     2221 gatagttgct tcttttaact cagcaacgat gttttcaatg ttcaatgcca ttataatttc
     2281 ctccgtttaa ttgttctttt ttatttaatg ctttatgcgg caattaagct gcatctccat
     2341 cttctttgtc tgccactgct ttgacagcgt aagccacgtt gcggactggc gcttgtagta
     2401 cagatagcaa catagataga agtccttcgc gatttggcaa ttttgccaat gctgtgattt
     2461 cttccaatga agagacttta ccttcgatga taccgccttt gatttctaat gcttttgctt
     2521 ctttagcaaa ttcgtccatg attttcgctg gtgcgactac atcttcgtta ctgaatgcaa
     2581 cagctgtagg tccagtgaat acttcgtcca tgccttcaag gccagctttt ttagctgcac
     2641 gtgaaagaat agaatttttg ataactttca tttctacgtt agcatcacga agttgtttac
     2701 gtaaacgtgt tacttcatca actgttaatc cgcggtagtc aacgactact actgatgcag
     2761 ctgctgtaaa tttttcgctt acttcatcaa cgattgctgc tttttttgcg ataattgctt
     2821 cactcatttt tgagtttcac ctcctgaatt ttgatggaag agttttttgc actgaaaagg
     2881 caagtcactt ttatagttac tttgctcaac cagtattatt catcacctat tcacttcgtt
     2941 catagtgatt ctactcgctt tgctcgaaag gaaactcctt tcgctttgct caaccagtat
     3001 tgttcatcat ctcttcactt cgttcatagt gattcacaat aaaaaactct atgccaccgc
     3061 agacatagag ggactattga atatattcaa taaacgtcct cggtaggaaa ttaaggcttg
     3121 atgccaccta ctgtcttcgg tacaagttaa ttattaacct caactagctt agcatgctaa
     3181 actagttgag tcaagaatta tttttcagtt ggatcaatca acattctaat atttaattag
     3241 aaagaagctt ggtcaacatg gataccaggt ccaaatgttg ttgtgatcgt tacatttttc
     3301 atgtattgac ctttagctgc tgatggttta gcttttagca atacatcatg gattgctgca
     3361 aagttttcaa ctaatttttc atcgtcaaat gaaacttttc cgattggtac atggatattt
     3421 ccagctttgt ccacacggta agttacttta ccagctttca cttcgtttac tgcttttgtt
     3481 acgtccattg taactgtacc agttttaggg tttggcatta agccttttgg tcctaatact
     3541 cgtcctagac gacctacagt agccatcata tcaggtgttg caacaactac atcaaagtca
     3601 aaccatccgt tttggatttt ttgaaccatg tcgtcgtcac ctacgaaatc tgcaccagct
     3661 gcttcagctt cttttgcttt gtctccttta gcaaaaacta aaacagtttg tgttttacca
     3721 gttccgtttg gtaatacaac agcaccacgg atttgttggt ctgctttttt agggtctacg
     3781 ttcaaacggt atgcaacttc aactgttgca tcaaattttg caatgtttgt ttcttttgct
     3841 aaagctactg cttcggcaac aggataaact ttacttgaat caactttttt taatgcatct
     3901 tgcatttttt tgctcttttt agccattttg gttcctcctt gattgtggtt ataacggttg
     3961 tacctcccac gtgttctata tctttcaata tagagccaac tgagaagctg ctgtcttagg
     4021 gtgtatagat tattctacag tgatccccat gcttcgtgca gttccttcaa ccatgcgcat
     4081 tgctgcttca acgttagctg cgtttaggtc ttccattttt aattcagcga tttctcttac
     4141 ttgatcgcta gaaactttcg caactttatt tttgtttggt tcgcctgaac ctttttcgat
     4201 tttagctgct tttttcaata gaacagcagc tggcggtgtt tttgtaacga atgtgaatga
     4261 acggtcttcg tatacagaaa taacaaccgg aatgatcaaa cctgcttgat cagctgtacg
     4321 agcgttgaat tcttttgtga atcccatgat attgataccc gcttgaccta gtgcaggacc
     4381 tactggtgga gctggagttg ctttacctgc aggaatttgc aatttaacga ttttttctac
     4441 tttctttgcc acgagacata cctccttaag tccgtgatgt ggttaattgg agatgcatat
     4501 ttctcctccc acgttttatc tgatctgaaa aaatccagac aaataatgtg caaaacaatg
     4561 cacactggta cagtatagca aatttatttg ttttttcaag atttttttct gctattttta
     4621 cattttgctt gaataaacgc taaatttatt ctaaaaaaac aacaattttt cgttctcatt
     4681 tcttctttta tgttacactt gcgctagcat ggttcaacag atgaaagcaa acaataacac
     4741 ggttttttag acccttgtac aaagattcct acataacaaa atgaggtgga gaaaatgaaa
     4801 gatttaaggt atagaagtgt ctttgatatt attggacctg tgatgattgg tccaagtagc
     4861 tctcacactg ccggagctgc tagaatcggg aaaatcatac gtagtatatt tggcgaacag
     4921 cctgattctg tagatattta tctatatgaa tcatttgcaa aaacctatcg ggggcacgga
     4981 acagatattg cattagttgg cggcctgtta gggatggaac ccgatgatga acgtttagct
     5041 gattctttga aattggcata tgaagccggt atggaagtct tgtttgttcc taagagtgaa
     5101 aaagccgaac atccaaactc tgtaaagatg cttctaaaaa aaggaacacg aaagctttca
     5161 gtcactggca tttcgatcgg cggtggcaat atccagattt ctgaattgaa tggattcaaa
     5221 atttctttaa gcatgggtac tcctaccttg atcgttgtcc accaagatgt tccaggtatg
     5281 attgctaaag tgactagtat actttctgag accaatacga atatcggcac tatgacagtg
     5341 acacgggaat caaaaggtga aaatgccatt atgataattg aagtagatga tcctcaagta
     5401 gaagaaacgg taaaaagact caaacagctg ccaaatatcg acagcgtaaa ttatttcgat
     5461 taaggagcta aaaaaatgtt tttatcgatt gaagaattag tagatcaagc aaaagcttat
     5521 ccaagtgtag cagaattgat gattgcagtt gaaatggaaa tgagtggccg ttcccgtagt
     5581 cacatcatcg agatcatgga aaaaaacctc tcagtaatgg aacaatcaat caacgaggga
     5641 aaagaaggtg ttacctccgt cacaggaatt accggtggtg atgcaaaaaa attagatgat
     5701 tatttaaatg aggcagactt tttaagtgga gaaacaatct taaaagctgt acgcaatgct
     5761 gtagctgtta atgaagtcaa tgcaaaaatg gggttgattt gtgctacacc gactgccgga
     5821 agcgcgggtg ttgttcctgg tgtgctgatg gctgtccgag atcggcttga tttgacacat
     5881 gaacagcaat tggaattctt atttaccgct ggcgctttcg ggttagtcat cgcaaacaac
     5941 gcttctatca gtggtgcaga agggggatgt caagcagaag ttggttctgc aagtgcaatg
     6001 gcagcagcag ctttggtttg tgcaaaaaat gggactcctc atcaagcagc acaagcagta
     6061 gccattacat tgaaaaatat gatgggactg atttgcgatc ccgttgcagg cttagttgaa
     6121 gtcccgtgtg tcaaacgtaa tgctttaggc tcttctcaag cttttatctc tgctgatatg
     6181 gcattagcgg gtatcgaaag tgtcattccg ccggatgaag tcgttgctgc aatgtaccaa
     6241 gtcggacgtc aaatgccgtc gattttcaaa gaaacagcag aaggtggctt agctgttacg
     6301 ccaactgcta aacgacttgc ggaagagatt ttaaataaga gggcgtgata aagctcctta
     6361 atttcgagta ttaagagatt agttatcttc ataacaaaaa acgaagagag gactaattgc
     6421 ccttctcttc gttttttatt aatccatcaa tttcgtattt tttacttcat cgatcgtttt
     6481 tgttcctgca agttgcatcg tgatcgacaa ttctttgttc aggtgttcaa aaacagatgt
     6541 tactccttct gccccaccta gattcaaccc ataaatcact ggtcggccaa tcgcaactaa
     6601 gtcagcacca cttgccagag ctttgaagac atgctctcct cgacggacac cagagtcgaa
     6661 aatcactggt acacgtttgt tgactacttc ggcaattttt ggcaatactt caaaggacgc
     6721 aggacctcca tctaattgac gtccaccatg attggatacc cagataccat ctgcccctgc
     6781 agagatagcg attactgcat cttctggcga ttgtattcct tttacgataa ctggaagatg
     6841 ggtgatttct ttgattgttt tgatgtcatc tggtgtcaag ccttgttttg cagctgcata
     6901 aatttctgcg attccttttc cttcgccatt accacttgca ctttgttcgc tatacgcagc
     6961 taagttaggc attggtaatg gaaattggaa ttgattgatg acgtcttctt cacggtaacc
     7021 accgagcgtt gaatctgccg ttaaaatgat agctttagcc cctgcttcta ctgctttgtt
     7081 caaaatgaac tcattgaatc tgtcgtcttt actcatatat aattggaaaa actgcggtgc
     7141 gcctggcgct gcatcggctg cgtctttgat tgtcgtattt gcataagtgc tgatggaaaa
     7201 gattgatcca gcagcagcta ctcctttagc tgtatcagct tccccttttt catgtgccaa
     7261 tccttgggcc gctgatggcg cttggataat cggtgtatct aattcaattc cgaaaacaga
     7321 tgtatgcaaa tcggctgagt cgattccgcg taatatccgt ggcatgattt tctttgtatt
     7381 aaaagaagtc gtattttctt tcatcgtcca ctcatcttca gaaccaccgc gaatatagcc
     7441 aaaagctcct gcttccatgc gctcttttac acgaccttct agttaggcaa tgtttacaat
     7501 atcgattgga tgttcttcat tacttgtatg ataagtcata gtagatcctt ctttcatctt
     7561 cttgattaca tataaatcat actaaactta caaaaagtaa gcaaacattt actctcagat
     7621 acttttatcg ctattctttc caaataaatc gacttacaag ctgatctact tcttggtttt
     7681 catgaagcat actatgagag gcattttcac ctgtcactac tttttcctct atttcatttc
     7741 cgcgttgctt caacaacgca tagaccgcta atgcactgtt taacggtact gttccatcac
     7801 tcaagtctgt ttcatctagt tgaccagcaa tcaagaaaaa tcgagtggtt ataggaatat
     7861 taccgatcat ttgctggtaa tcttgatagc ggttagaaac gacagcaggc ccctttgcta
     7921 actcatctgt cagagactgc gcactatcat cgacaaaatc attaaaaggc gcgccaattg
     7981 ctgttaatgt ctgaacttgt ggcaatgacg tatcctgtcc atacgttcct aaatagcgta
     8041 gtgcactaac tcctcccatg gaatgcccca ctatgttgac tttatctatg ccgtagtttt
     8101 ctttcagata caaaagacaa gttttgatcc attctgcttg attccactcg ttatttttat
     8161 tatcttcaaa caatacttgg accatcggat tgtctgcttt tccagacaaa tctcctgttg
     8221 cttgtatttg tccatctgtt cctactgtta aaaccaattc ttttactgct tgctgatttt
     8281 tttccaaacg ccgcaacatc cctttaaagg aattttctgt cccgctgtag ccgtggaaaa
     8341 aaagtgttgg aatagtggtt ttttctatca ctttactgga ttctgccgtt ttttctttat
     8401 cagaaacttc agtagtattt atcttcgtcg tctggcaacc acttaacgca aacaaactga
     8461 taaggactaa agctgctgca gttgcacgtt tgcataaatt tttgattggt tctgtcatac
     8521 acctcttcct ttccatatag aaaaaagaaa gacttgaaag gccaatcata tgatcgacat
     8581 ttcaagtctc tttattaatc gattttatct acttgatcga aatcaagttc tgtactggtt
     8641 tcacgtccaa acatatcgat gttgactttc aatttttctt tttctccgtc aacttctgtt
     8701 acttgtcctt ctaatccagc aaatgcgcct tcgatgattt tcacgacttc gccaacttct
     8761 acttctagat cattttgtcg caggctcata ccgatagaac gcaagatatg attgacttct
     8821 tctggaagta atggtgctgg tttgcttccg gctccgtgtg aaccaacgaa tcctgtcaca
     8881 ccaggtgtgt tgcggacaac ataccatgaa gcgtctgtca tgatcatttc aacaagtacg
     8941 tatcctggga atgttttatg aacgatttct ttttctttcc catttttgac ttcagtttct
     9001 ttttcttcag gaacaacgac acggaaaata aagtcggcca ttttcatact ttgcgcacga
     9061 gattcgatat ttgcttttac tttgttttca tatcctgaat atgtatgcaa gacataccag
     9121 tttttttcaa aagattccat tgaaggctcc tcatttcatt gtaaaataaa aaaacctcag
     9181 tacacccgaa gtttttcttt cgcttcatta tagcactaaa agtacgttgt ggctagcgag
     9241 ttattttaaa atccagccaa ataagctttg gatggctgta tccattacgt aaaacatcaa
     9301 tccgaaaata atagaagttt cgatgactac taacgtatct ttacggagtt gttttctgct
     9361 tggccaagtt acttgtttga tttcatcttt tacgcttttt agaaatttca tgagacaacc
     9421 tcccttgcta ctgtttattt cgtttcttta tgtaatgtat attgattaca atatttacaa
     9481 aacttattga tttccaaacg ttcgccgctt tttccttcac tgactgattt tgtgtagttg
     9541 cgagacccac aaacggaaca agcgagtgct gcttttttct ttgccattta cttctgcccc
     9601 cttgctgaga atcagactta tacttcataa cagtatcacg taacttttta cttgtcaatt
     9661 tgtgaaataa actatctatt gttttggata aaattatgat atgattaatt tgaaattaag
     9721 ctaaaatgag acaattggag gtatagcgat gctattaaaa acacttgtat ataagaaaaa
     9781 agatctgaca accgttacag agactagtac attagaagaa gcattaaaaa ttttagaaac
     9841 ttccggatac cgttgtgtgc cgatcttaga ttcttcaggt aatattttcc gtggaaacat
     9901 ttacaaaatg catatctatc gtcataaagc aaatggcggt gatatgacgc ttcctgtcac
     9961 tcatcttttg aaaaacgcta caaagttcat ttacctggat acttctttct tcaaagtatt
    10021 ctttacgatc aaagagcttc cttatattgc tgtccttgac agtgaaaatc atttttatgg
    10081 tattttgaca catagtacgt tgcttaatat gctctctcaa tcttggagcg tagaacaagg
    10141 aagctatgta ctgacaattg cttccacagg aaagcaagga gatttggctg ctattgcaaa
    10201 aatcatttca aaacacagca gcattgccag ctgtattact cttgatatcg aaaaagacga
    10261 atacattcga cgtacattga tcacgctacc ggctaacact gaagcgaaag tatgtgaaac
    10321 gatcgtcaac cacttagaga aaaagaatta taaagtggta gaaattgaaa atttgcaaaa
    10381 ccaagaagca taatcaaaaa gcgaaaaaag aaaacagcta atctgctttc ttttttcgct
    10441 ttttataatt agacacgctt ttcaaaatca agcgcgcgat ctaaataata catcaatggt
    10501 gctgaaacag ccatgacgat aaactcactt aatgcaagcg tgccataggt tgtccaaaat
    10561 gcttggccac ctgttggaac taacatataa gcaatcagtc ccatgctgat ggtaaagaag
    10621 atcgtgttca atactaaacg catctttaca tttttcactt tgttttgcaa taaagctgtc
    10681 aggcctaaag aaagcaatgt ttggccgcca ccaaaaacca catccatgat accaaaacca
    10741 aagaaggcat tatagacgat gaccccgcct aaaactcccc aaagcaattt acggttaaag
    10801 acaactaaat gattcaaact ttctgaaata cgaaactgga tcggccctga ggatacaggc
    10861 gcaactaaaa tagttaacgc tagataaaga gccatgatga tgccatttac aacgattacg
    10921 gataaccgtt gtctgctttt cgttttttgc attttctctc ctcttttctc ctagtttttt
    10981 taacgcggga tggttgatga accgcggtta tgtgaaacaa acaataatta taacagactt
    11041 ttcatttatt tcaatccgtc ttatctgctt ttaaaaaagc aaaagcttaa acaatgtaaa
    11101 cgtttgctaa aaatcgtggg atatggtata aagtaagtgt aaggggtcat aagaattccc
    11161 agtaaagcag acgaagtagg atctgcaaga acagaattgt tgtgaaactt aaataaataa
    11221 aaaaggatgt gggaatttga gcaacctctt actagagaac ggtctagcaa gcagctgaag
    11281 atctaagtgg acatgccgaa ccttggaact tctccttacg taagtaatgg atcatgcgct
    11341 tgctaggctt ttttgtgttt ttcggtcttc ggaccttttt cattttccta gacttctgct
    11401 ataataacca agaattaatt ttgtaacaga tttttttgaa aaaacaagtt tctttcattc
    11461 aaaaaataga aaaagcttgc taattattgg ttaaccagca aacaggagta ttaaaatatc
    11521 ttgttttatt gaatagcagg aggaaatcat gaaattccat tatcatatat tgatcaatcc
    11581 atcggcaggc agcggaaatg gctataaagt agcagaaaga attttaccgg tattaaaaaa
    11641 taagcatatt gactatacac ttcattatag tgaatacaaa ggacacgatg ctgagattgc
    11701 tgaaactttg gcaaaagaaa cattgattcc ttggatagaa gaagaacaga aaacaatcga
    11761 tactttcccc cttttgatca tcgtaggagg tgacggcacc ttacatcagg tacttgatac
    11821 tttctatcag atggaagtag aattcccagt tgcttatatt ccagcaggtt ctggaaatga
    11881 ttttgctcga ggggcaggcc ttccaaaaaa tcccaaaaaa ggacttcagc tgattttagc
    11941 agctcaatca ccagaaaaag tccacataat ggcttatgaa gaaaaaataa gtgaaaaaaa
    12001 aggaatagct gttaataatt tcggtatagg attagatgca gctatcgtcc atgcgacaaa
    12061 tcattcttcc acaaaaaagc gattgaacaa atacaactta ggatcatttt cgtatttatt
    12121 ctctattctc cgtgctttat tcactcaaaa aggatttcca attctggtag atgcaggagg
    12181 aaaacaatta agtttttcaa acgcattttt atgtacagca acgaagcatc ctttttttgg
    12241 cggaggaatc gcgattgttc caactgctga tgcgtctaaa ccagtcattg attttgtcgt
    12301 ggtcgaacga atcaatttct ttaaaatctt gtggctcatt cttttactta tacagaaaaa
    12361 acaattgaaa tcgaaatatt tccatcacta cacaacaaac agattacgta tcgtttcaac
    12421 aacaccgcaa catggtcaag aagatggaga agaaatggaa aaacgacctt ttgatatcac
    12481 aataaccaca actaaacagt tgttttggtg ttaataaaag aggttttgtc agaagctaca
    12541 tctggaacac cgtttattcg gaaaaaagga ctgtgacacg acttttgtca cagtcctttt
    12601 tttactatgc agttaattct ttgcccaatt gggttgccat cgatagtttc tttctttacc
    12661 caaaataaat tggatcattg aaaacaccgc agcaaaagca actaagacac aaccattgaa
    12721 ccaaaaagat tctgcaaatg tttgattgta actgagtgtt tcactgatca agttattatt
    12781 ttgaacaaac caatatgttg gtgtgaatgc cgctattttg ctaaccattt ctggcaagta
    12841 ttctgctggt acaaacaccc caccgataaa gcaactgcct gtgataaaaa tatctttgat
    12901 cccaccgctg gtttctgagt tttttaccaa tgaagtgata caagccgaaa agctaatgat
    12961 cggcaataaa aacaagaaag tatttaaaat atgataccat accgttatat cccacgaggt
    13021 gtggatcact aacagaacca ttagaagtaa gaagccactg aacaacagca gcgagtaact
    13081 aatcaaacta aaggttactt tgcgattcaa gtttcgtttg gtaatgggcg cactctggtt
    13141 tcgtttactg atctctttgc gattaaacgc tagattgatg acgctgaaac cgctaaaaat
    13201 ggatagaaac aacccataag acaagaaatt aaaggttgtg cccgtcaaca gctttttcat
    13261 ccgctgacta tatcccgcac ttagctcaac ttctccagta accgagagtg ccatttgtgt
    13321 ctgttccata gctgcatcga ttgttttatc ttcttcttga aacagaatca gtgtttgcaa
    13381 aaaggtgttc acttgctgtg taacaactgt tttagaaaag gcatctgggc gactctgtat
    13441 cttgatcgtc gccatctttc ctacttcgac ttgttcggta aagtctgcag gcagatgtaa
    13501 gataatgttt acacgattaa aataaagagc atcatcgatt tctttttgtg aggttccatc
    13561 caatgtaacg actgtttcct tgtcattcaa atatttacga aggccatcga ctacaggcga
    13621 ctcttcttca ctaatcaagg cgattttcgc atcttgcaga gaggtatttt caacatcaat
    13681 attttgcgca aaaaagaatg tggcaacaac agtgataatt acacctatca gtaaattcga
    13741 tttatttgct ttaagcaatg tccaaatcgt tttataaagc gtcataacgc acccctcttt
    13801 ccatccaagc atttcctaac gcaaaaagga aaataaatcc gatcaaccat agaagattgg
    13861 tataaaaact agccaaatca gtgtagaaat aaagtttata caaactttcg ctgatcaagt
    13921 tgacgagatt taattgacca acaatcggaa tatgaagatc aatccaatac ttcacttgtt
    13981 ccgaccccat cataccagca aaaaagctca tcgcaatcgt cactgaaatc aagatgctat
    14041 ccttttgcac cagattcatt tttggtatca aattaccaac caatgtacct aacaaaatcg
    14101 cacacaacga ccccagagcg gtaacaatca tcaaccattg ccaacgttca ccaaagtcta
    14161 cttgatagat aaaacgaaag acagctaaca taatataaat ctctgtcaaa acaatcgtaa
    14221 agcttgctgc caaattagcg attgaaacta acgattgctt tctaggaatc aaggacaagc
    14281 gaataccatt tgacgattga tttgcttgct gatcctgtac attgcggacc ccccacatcg
    14341 tcccgtagag aatcgccatt ccaatcagag tgaagaaata aaaacttttg aaactcatat
    14401 tacgacctgc atgaacttct tgaaaagata cttcttgttc aaaaacagtc atgatgggcg
    14461 cgagatcaac gttctccact tctgccactt tactcgaaat tataccaata cgctgtaaaa
    14521 attgatccat gacgtttttc atcaacgtct gactcattcc tgcttgaccc acatggagcg
    14581 aaacagatga accatcaatg agataaaaac cagccaaatc atctgcattt agcttttcat
    14641 tcgcttctac ttccgatagt tcctgtactt caaataatgg tttatcattg acttcgactt
    14701 gttctaagac tgtggtaaaa ttttccgaaa gcgctgtttg atccgctttg attacaattc
    14761 cagtattaat cgtttcaaga ttgccacctt gatcaatctc gccaaaggcc gccataaaca
    14821 tcaatcctaa aagaattgga aaggccaatg tccaaaacaa catggattta tttcgcagca
    14881 gtatttttgt gcgatattta taaaaatgcc aaaacattat ttcccctcct ctagtctctc
    14941 aaatccttgc cagtaatctc taaaaagaca tcattcaagg acgcttcttt ggttgctatt
    15001 tttccgtaac tgatcttttc ttcttgtaag attgtaagaa tcggcaacaa tactgtattt
    15061 agttcagtag ttgttacttg gagctgacct tttttataag cgattccatc agaagctatt
    15121 gttcgctgaa tcgctgacaa cacattttct gggagtaatg ggatgtcgat cgtcaaacga
    15181 tccgccgtcc gtaccatatc ttttagagat tctttggttc ctttagcaat cacctgtcct
    15241 tgatccatga tcacgatctg gtcgcaaaga atttctactt cttccatgta atgtgttgta
    15301 tagacaatgg ttgctccttg tcgattcagc tccttgatac tttctaaaat tttattccga
    15361 ctttgggggt ctacagctac tgtcggctca tctaaaaaaa ttaaccgcgg cttgtgggca
    15421 atcccacatg cgatgttcaa ccgacgtttc aagccaccac taagttctcc tggacgaaac
    15481 gaaacatatt tttctaatcc cactaattga atcacctctt caatcaaggc tttccttttc
    15541 tctttttcgg aaacatataa accgcaaaaa taatcgatat tttcttgcac acttagttcg
    15601 tcaaagaccg caacgtcttg aggaacgacc ccaatcattg ccttgacagc ataattttca
    15661 ggagtcattg ttgtcccgaa caatttaatg gttcctttgt cataatttaa caaagaaagc
    15721 atacagttga tggcagtcga tttcccactg ccgtttggac ctaacagacc taagacttct
    15781 ccttcttgta cttgcagatc aaaatgattc aatgctacaa aatctccata gcgtttgact
    15841 aatttatcaa tttcgataat catcatgaaa aactccttcc aaatttcttg ttgatctgac
    15901 tataataaag tgcaagaaaa gaaactagtg acgattggct aaaccacaca tgacatttgt
    15961 cacaatgaag gagtctgcta tgcataaatc tcggctactc aacgaaacta gctttctact
    16021 ggttatctca ttgcttttgc tggtaagtca aggattcgtt gctatgcaag ttatctattt
    16081 attgatcgcc gttttattca ctggtgtcag ttatttactg cctacaaagc caaattggat
    16141 tttccaagtt attctatttc ttttatgtgc ctttttacct gatcttgtcc tgtttctgcc
    16201 agcgacgatg cgagtgatcg cccctgaaga aagccacctt gattacttgt ttttgttagg
    16261 ttttttgttg atttcgacgg ttggtaatca tccccccatc aaggtcgcct ttgtcgtaat
    16321 tttgctgttt ttttcctttt acttacgaaa aaaagatcaa cgaacgaccg atcttgagaa
    16381 aaagtacatt gtctccaaag atactcattg ggaaaaacaa caagagttat cggaacaaaa
    16441 taaagcattg gccctgtcac aagaaacaca attagccttg caaattgtgg aagaacggaa
    16501 ccgaattgcc cgagacatcc atgacaatgt cggtcatctg ctgtcaagtg cgattttaca
    16561 aattggtgcg cttgaaatga tcaatcaaga accaaaacta aaagaaccat tagaaaattt
    16621 aagtgccacc gttcacactg ggatggatcg gattcgtcaa agtgtccatg acctccatga
    16681 gacatcgatc tcttttcaac actccttaga gtttctgatc gctgattttc cttcttctgt
    16741 tacgattgaa ggaaacttgt ttgaaggatt gaatgaaacg cagcaaaact gcttcttaat
    16801 ggtcatcaaa gaagccttaa ccaacagtat caaacatagt catgccaaaa ccgttgtttt
    16861 acattttcga acgttgccgg ccttttatcg cttgcaaatc acgaatgatg gcaccagccc
    16921 acaaaaaaat tctgctcccg gtattggttt gaaaacgatg cgtcaacgtg ttcaagaaca
    16981 aaagggacaa gtccatattt tccaagaaaa ccagcaattt cagttaacga tcattttacc
    17041 aagggaggga caccaatgat aacagtagtc attattgatg atgatccatt tgtgacgaaa
    17101 tcgttacaaa ccattttaga aagcacgaaa gagatccgtg tgttaggcat tggtcattgt
    17161 gccaaggatg cgctagtctt atacgaaacc catcgtcccg atgttttgct gacggacatc
    17221 cgcatgccta aacaaacggg catcgatgct gccaaagaaa ttttggctaa atttcccaaa
    17281 gccatccttt tgcttttgac gacattcaaa gatgaagaat acatccgcga agcattttcc
    17341 atcggtgtca aagggtattt aatcaaacag aacttgcaag cgattattcc ttctgtcaaa
    17401 tccgcttata atggacaggc cgtatttggt aatgaaatca tcgagacttt cactcaaatg
    17461 atgaagaata aaccgacgat tgatagtcat gcttatgctt cttttagtga acgtgagctt
    17521 gcaatcatca aagaagtagc tgccgggaaa aacaataaag aaattgcaga tgccttgtac
    17581 ttgagtgacg gcactgttcg caattacatc agccaattac tagaaaagct agatttacgg
    17641 gatcgcacgc aattggctat ctatttttat cagcatttgc aataagtctt atctaacaca
    17701 aaaaaacctg aatgatgctc cttcgcatca ttcaggtttt tttcacatct tctattcaat
    17761 tgtcccgcaa accatttcct cacgattgaa agaatcaagg attcgcaggg ctgccaggat
    17821 tcgttggatt gttcggcgtg ttaggcggaa aaataggcgc cttgtctaac gttttttcta
    17881 gttttgattc ttcacgatcg tctcgttcta catcaggact ttcattcaat ttgaattctt
    17941 tttccatctc atctaacttt ttaaagtcat tgccagattc ttttgctaat ttcgctaatt
    18001 tatcttcggt ttctttagcc ataaagtaac gccccccttt tgatttcagc ttagcatatc
    18061 acactgaaaa aacaaaagaa aacgctaacc aacgatcatt tttagctatt tctcatcttt
    18121 aaaatcaagc attttttgcc ggtataaaat cgtagggaga actgttttcc ataccaatca
    18181 tcggatctac taactggtta tcgatcactt ctgctgtaag aacgaaatct ttagaaacag
    18241 caggttctac ctcttctttc ttttcttctc caacaaatga agaaaacaga tctggttcca
    18301 ctgtttccat tacttggttt ttcgtttcat tcgtcccact gtcatcttct acaggtagct
    18361 tttcttttac aacccgtggc tcttttgtat agttcccatc ttcaaatgga tcatttccga
    18421 ccaaagaatc ttcataagct gctagtttgg tccggagagt gatattcatt ttatcattat
    18481 ccatgatcct tgatttcaac gtagtcatcc ggcttgctga ttcattcgct acacaagtga
    18541 cataggcttg ctcttcccct aacaaaatca acagttcctt actgcgagtc actgccgtgt
    18601 agagcaaatt acgctgaagc atccgctgat attgatggac catgggcaaa ataaccatct
    18661 tgaattcact gccttgtgat ttatggattg agcaacaata agaaagagtg attttattcc
    18721 attcgtttct tttataagtg acctcatttg catcaaactg gataactaat tcatccactt
    18781 tatcttcaga atcttttgcc aagatgatac ccgtgatttc tcccatatct ccattgaata
    18841 cattcaattc gggagtattg actaattgga ggactttgtc tcctatccga taaacggtgt
    18901 cgttccaatg tacttccttt tttccaggtt tccctggatt gaatatctcc tgcatcattt
    18961 tatttaacgc atcgatccct gcaggtcccc gatacattgg tgctaatact tggatatctt
    19021 gtgcacggaa tcccttattt ttcgcttttt ccacaatttt agagatcaag ggttcaattt
    19081 gataagcatc acttcggaaa taggaacgat ctttttgatt ctttgtgaaa tcttttggca
    19141 gacgtccttc tttgatctca tgggcaagag gaataatact agaaccatca ccttgccgat
    19201 aaatctgatt gagttccatt ttgggaattt gttcgatttc caaaagatca tggagtactt
    19261 gaccaggacc gacagaggga agctgatctt tgtctcctac taagataact tgcatattcg
    19321 tcggaatcgc tttgaataat gtgttagcca gccatgtatc gaccatagac atctcatcaa
    19381 caatcaaaag tccgccttct aattctttcg tactgactga aggtgttttt tcccgtccat
    19441 tcagccccag aagacgatgg atcgtactgg caggcagacc tgtcgtttcg ttcattcgtt
    19501 tagctgctcg gccagttggt gctgcaagta gaataggaaa aatttcttgg gtatattttg
    19561 aaggatccaa ttccagtccg ttcaactctg caaaaagatt gacgattccg ttgatcacag
    19621 tagttttccc cgtacctggt cctcctgtta aaataaatag aggggaacgg attgcttcag
    19681 cgatagcttg ttcttgcgaa ggtccatact gtatgccgaa tattttttcg atacgccgaa
    19741 tattcttctg cacttctttt tcaggataat ggatttcttt tttacgactg agaaggcgct
    19801 ggatcgaatt accgatcccc cattcagaaa agtacaaact gttttcgtaa agattagtct
    19861 cttcttgttg tatctttcct tcttcaacaa gttggataat tacagtagca acctgatcag
    19921 gctggatttc aattgggcga cttgtttcta aaatacggat cgtttgctga agcaatgtct
    19981 ccgccggtac gtatgtatct cctgtttgaa ctgcatgctg aaaaatctga tgcaagatag
    20041 ctgctcgaat tcttctcggt gaatctgctg caataccgat ttgttcggct agattatctg
    20101 cacgtttgaa cccgattcct tctatgtctt cgactagctg gtacggattt tcttcgatga
    20161 tatccaaaga ctcgttctta taggcctggt agatactgaa agctaactga ctaccgaacc
    20221 cgtaacgatt cagtcccatg atcacttgat ccatcccgtg gtttagccga atcgtctcag
    20281 caagcatttc tctttttggc ttcgtcaaac cggagatttg ttttaatacc gaaggatcag
    20341 caatgatttt ttcgatagca tcttctccca gcaattctac aattttttct gctgttttct
    20401 tcccgattcc tgggaatttt tcgctggaaa gatacgctac gatcccattt gcagttgttg
    20461 gcttttcttg ctcatatctt tcgagtttaa gctgccttcc gtatttagga tgatccacta
    20521 attctccata aaaacgataa gtctcatttt cttgaatatc gccgaaactt ccggtgacta
    20581 caatctcttt ttcacggtaa tcagctgtgg tttcactgat gtgtaccaaa agcactttgt
    20641 aaaaattact aggattttga aaaaaaatcg cggcaactgt accaacgaaa taaggcattt
    20701 cttctggctg catcggaagc cgcctccttc ttctatagta aaggttctgg tgctgtttca
    20761 gttcctaaaa aatctgtttg gttccatact ttcagttcat atggcaataa tctgcaaggc
    20821 tcttcagtct ctaaaatcgt caaactacta ttgaacaatc cacccatttc acgcaactca
    20881 cttagctctt ttcctgtcat ccattgaatg gctgcagtta aagaagctcc atgtcctacg
    20941 aataaaagtg ggccatcttt atgtcgggca accgcatctg ctacaacagt ttcgatacgt
    21001 gtgattgccg attcaatcgt ttctccgtga aaaggagaag gatcatacag atctaaatga
    21061 ttacgcaaat tcggcagatt atccggatat ttctggtaca tttcatcgat cgactgacct
    21121 tctaaagtac ccagccctag ttctcttagc ttatctgtat aaaaaatctc taccggacga
    21181 gcaagctctt tgttgatacc ttctgctgta tcacgtgctc gctttgctgt actggaataa
    21241 attgctttaa aaggaacata ttttaccttt ttcccaaatg ctttgatttc ttcgtaactt
    21301 tgtggcaaaa gcggagaatc gccattgctc ccttgaaaac gtctttcctg attccattgt
    21361 gtcttcccat gtcgggtaaa atatagttcc atacgcagca aactcctgtc tttcttttat
    21421 tttactctat aataaactgt ctaatccagc ttgtcatttt catagtgatg cgtcaattct
    21481 aaattaggga atccttgctg gcgaagtgct tcatacacta tcattgcagc tgtattcgat
    21541 aaattcaatg agcggacatg ctcatcattc atagggatgc gtaaacactt ttcttcgttt
    21601 tcacgcataa atgtttctgg caaaccggtt gtttcttttc caaataaaaa gaagtgctct
    21661 tctccatcag caaaattttc gtcactatat actttatggg caaattttga gatcaaatgt
    21721 agtttacgat tacctaaaaa tgttaaaaaa gcttctaaat tactgtggta agtaatattt
    21781 acatcattcc aataatccaa ccctgcccgt tttagatgtt tgtcatcagt tgaaaaacct
    21841 agtggctcga ttaaatgaag cggagtattc gtggctgcac acgtacgggc aatatttcca
    21901 gtgtttgcag ggattaatgg ttcaaataaa acgatatgat tcatcaggat cattcctctc
    21961 atatttatgt tcgtttctat tttctgacaa tttgattttt gcataaaaaa aaacgtatca
    22021 actcggtgtc agtcactgcg agtcgttacg ttagtgaagc tcttctcact aacttttatc
    22081 agaacaggaa cctgataaaa accaatgaaa aaacaacttg ttgctaatat aacaccctca
    22141 actttttttt gcaacctcta ctcattaaaa actgctagaa aaacgttttc tcttagttcc
    22201 ttttaataat tctatgtcaa ttgtaatctt cttcaaagga ttcttatata agtctgcttt
    22261 gattcgctct tctacctgcc attctaaagg tgacatggcc aaaagatctt tttgattttc
    22321 ctctggtatc tcaaattcat aggttacacg ctgacgttca gttaatttca ttgcttcagc
    22381 aaacttggct actacacgtt cattggaata actctgtttt tcaggttgat tcggataaaa
    22441 agcctgacgt agttccttta aataattttc ttgtggcacc accttcaaca cttctccatc
    22501 ttctgagagt acacgttgga attcttggta atgagaaggc gaaaagatat ttaaaaccgc
    22561 gttgaatgtt tgatcagcaa acggcaaatt ggtcaaatca gctacacacc aaaatgcttc
    22621 ggcagattgt tctgtagctg cgtagactcc ttcttttgaa atatcaaatc caacagcatt
    22681 ttgaatcttt ttcaattttg aaagttcatt caagaagcta ccttctccgc agccaacatc
    22741 taatagcgag acttcttcag gtaaatgctg cgcaatagtc tcaataacgg gctgatacat
    22801 gccagattgg atcattctac gccttggaac gaacattcct tgatcgtatt ctgttttaac
    22861 cgcatgggat aaaaaataaa gtgttccttt tttggaaagg tcaaaacggt gattattttt
    22921 gcatatcaag ccattatcag acttttttac ttcttcttgg caaaccggac agcggaacag
    22981 ctgatgattt tctgccaaaa actggcgtcc tcggtcaatt ttttttaaca tagttccccc
    23041 tcatttctgt tttatcttac cgttagatgc tcactttggc aactgctaaa aatatgatac
    23101 aatgcctaga agaaagtgaa agataaagga gaagattaga tgatcaaaga attttgcgct
    23161 gaaaactaca catctattcc tctagcaatt gctagaggag ccgatcggat cgaattgtgt
    23221 gacaacttag cggtcggtgg cacaaccccg agtactggtg tgatcgaaga aacgttaagt
    23281 tatgctgggg aaaaagatat ccccgtaatg acgattattc gtcctagagg gggcgacttc
    23341 gtctataacg atatcgaatt gaaaatcatg catactgatt tgattgaagc aaagaaatta
    23401 gggacggatg gcgtagtatt tggttgtctt actccttcag gctggctaga cgaagaggcc
    23461 ttagaactat tgatcgaaac agcagaaggg ttgcagatca ccttccatat ggcttttgac
    23521 agtattcctg aagatcggca attcgaagca atcgattggc tggtagaaca tggtgttgac
    23581 cgtatcttga ctcatggcgg tcctgctgac aaaactattg tagaaaattt cccacggctt
    23641 aaagaattga ttgcctatac agatggccgc ttaatcattt tgcctggtgg tggtgtcact
    23701 gcagagaatg cagcacatgt agctaaagaa ttgaacgtaa gcgaagtaca cggaaccaaa
    23761 atcgtggatc ttcagttata atcttataaa caaaaaaaca tttgcaacag gcataatgct
    23821 tattgcaaat gtttttgttt ttttacataa aatagcccat aaataaagaa gcaatattga
    23881 aataaatcag tacactcgtc aaatcgctca aagtcgtgat aaagggaccg cttgctactg
    23941 ctggatcaaa tcctagacga tccattagca tcgggattaa actacctgca agattcgcca
    24001 ctgtgattgc aaatagcata gccatcccta tgacaaaccc caagataaaa ttatgtttcc
    24061 aaaaacctac gattagaaaa atcgtgatcc ccgtaacagc tcctgtgaca acgccggtca
    24121 agacttcagc caaaacaagt cgaacaaatc catgatcttt ctcatcagaa atcgcaagtc
    24181 gacgaacagc cacagctagc gactgggttc cagcattacc ggcagttcct gtaatcagcg
    24241 aaatgaagac tgctaaaata ctcgcttcac ttaccaagtc ttcatagtga ctgattaaag
    24301 aagcggtcga catacctaaa aacaacagag tgatcagcca aggcaaacgt cgagacgctg
    24361 cctttactgg attttcatta atttcttcca cattgacccc ggcaagtcct gaataatcgc
    24421 tagcagcttc atcatcaata acgtcgatga tatcatcgac tgtgacgatt cctaacaaat
    24481 gatcatcata atcggtaaca ggaagagcta agaagtcata atctctaaat gtttgtgcca
    24541 catcttcttg gtcgtcgcct acatgaactg aaagcactcg ttcgctcatc agatcagaaa
    24601 tcattgcgtc gtcatcattc acgattaggt cgcgcagaga aataacccct actagctgac
    24661 cttcttgatt aacgacatag atgtaataga ttgtttcagc tacatctgct tcgttcttca
    24721 gcacgtacat cgcagagcga acagtttgat tggctacgat cgaaacaaat tcagttgtca
    24781 tgatcgcgcc agccgtttca tcctcgtaat ggagaagttc cttgatttca ctggcatcgt
    24841 ctgccgacat caaacttaaa tatttagcaa tttgcttttt atccagcgta ttaagcaagt
    24901 caacagcatt atctgtatac atctcagaaa gcatatcagc tgcatagcta ggacgcattt
    24961 catctaggta ttctttcata tgttcgttgt cttcttcaat cacatcgaac atatccgcta
    25021 attctttatg cgacagatag gaatagatca gctgcctgtt ctcttctgta agagattggt
    25081 agaattgccc ctgctcatag atatgcatct ctaaaaaact gtttctgaat gcctgaatat
    25141 tattttccct taaatcttga gtcaactggg caaatctttc ctctaattct tgattttcat
    25201 ccaaaccaat ctcacctcgc cttattcttc aaaccgtctc acaactgcct ccatgtctgc
    25261 ggctaaaggc tgcttgaact ccagcaactc ttctgtaaat ggatggtaaa aacgcagatc
    25321 ataacaatga agggcttgtc tttttattcc cagatccatt cgcccgccat acatatcatc
    25381 accgagcagg gcacagccaa ttgcggaaaa atgaactctt atttgatgtg tccttcctgt
    25441 atgcagctgg atatcaacta acgcgatttc tgttagtcgc ttctctatcc agtactcagt
    25501 ctgtgccgaa cgtccttcat cagagaccat tcgcttcaat agcgaagaat aatctcgggc
    25561 gatcggcaaa tcgatatgtc catgtgccga taaatctgaa agccttccac tgactaaggc
    25621 ctgatatttt ttcacaaact tcttttcacg aagttgcata tctaattttg cgtgcgcaaa
    25681 tccatgcttt gcaaaaagca tcaagccaga tgtatcccga tctagtcgcg tcaccacatg
    25741 gattacttgg ttttcgtaac cttgtttttt ataataagcc tttacacgat tagccattgt
    25801 cccatttgga tggtattggg caggaataga cgaaacgcct gctggtttat ttactaccag
    25861 aacgtgttca tcttcataca cgatatcgat cggtgtttca tccaaaagta cggtttcatg
    25921 ttctccttca gcaggaatca caatggttac cttatcatcc ttagctagag aaaacaagac
    25981 attttctact tgatcattaa ctttgatttg accgccttga aattttattt tcgctaacag
    26041 accctttgag atcccttttt cttttaaaaa atattttact tgctgagaat gatctttctc
    26101 ataatcccat gtaaactgca tatcaatcct cactaataaa ggcatctttc acacgatgcc
    26161 aaaaatgcat atgtcgataa gaagcaaaat ggatccgttc ttctgctatt cgataataaa
    26221 ttgagcggat atttgctttt gcgacattca attgatcaac cgttacaaga taatcttctg
    26281 tattttccaa ttttatttct agccattcat catgggcaat cacgatcgga gaacccaaag
    26341 tacgaaacac tcgattattc agtgaagcaa tctctgccaa ctgaaaggca ttgatactag
    26401 gatggatcac agcaccgccg acacttttat tatatgctgt cgaaccagta ggcgtagaaa
    26461 tcgtcaatcc atctcctcta aaactttcaa acagctcgtt tttgatgtat acatcggcta
    26521 ccatcgtacg attggcccgt ttaatcgttg attcattcag tgctaaaaaa tgctggtccg
    26581 gtgtttcatc caaataactg atccgaacat ccagcaaggg ataactaaca ctttgttccc
    26641 ggttcgttcg taagctgtct actagttctt ccagctcgta atcccgccaa tccgtgtaaa
    26701 accctaaatg acctgtatgc acgcccaaga aacgcacatc attcagacaa tgactgtagt
    26761 gatggaacgc cgacaataat gtgccgtctc cgccgactga gatgaccaat tctggctcat
    26821 gatcatctcg ttgaatccct gcttgttcta aaagtgcgtt caaacgttct gtcacttcta
    26881 tagtctttgc ttctttatta tgaacgatcg ctactttcat cccctgcctc ctctctttcg
    26941 ctttctttct tcaaaagcgt tcgatagtag acatcatctg attttcctct tccatgggag
    27001 aataaccgct gtgcttcttg gatttcttca cggatactgg acatctcttc atccaactga
    27061 taggcagctt ctgccgcacg ctgaagtcgt tcactcattt cttctggaaa aacgccttga
    27121 tatttataat tcagcgaatg ctcaatcgtt gcccagaaat tcatcgcaag agtccgaatc
    27181 tggatttccg ccaaaatttt cttctcaccg ctgatcagct gtacaggata ctcgatcacc
    27241 agatgataag aacggtagcc acttgctttt ttatttgtga tgtaatctcg ttcttggaga
    27301 actttcatgt cttttctttt acggatgatc tcaacaactt gatggatatc ttctacaaac
    27361 tgacacatga tccttaaccc ggcaatatca gacatttctt cttctaaacg tcccattgga
    27421 atatgccgta attgtgattt tgttacaata ctatcgactg gcttgactct cccagtgaca
    27481 aattcaatcg ggacatgtcg attttgttca cggaactgtt tgcggatccc ccgcagtttc
    27541 actttcaatt ctgatacagt ttgttcatat ggtgctaaaa atgcttccca atctcgttcc
    27601 atagctgata cctctacttc attaacattc attgtttatt ctaccatata tgcaaagttt
    27661 tttcgtactc ttgatttatg cattgaccaa aaaaagaaaa ttaggcaaaa tagacaaaaa
    27721 ggagtcgatc aaatgacaca aatgcttgaa atcgaatata aatctatgct gacaaagcaa
    27781 gagtacgaga tattcatcgc tcactatcaa ttaacagata aagatttccg tgtacagact
    27841 aatatttatt tcgataccgt tgatgaacag ctgaagaaac aaaattgtgg cctacggatc
    27901 cgtttcgttg gtcatcaagc tgaatataca ttaaaaacac ctgctgaaaa agggcgtctc
    27961 gaaacaacgg atacctttat aacagaagaa gcagaagcat ttatcttcga aaaacgtctg
    28021 cctcgttcag gcgcagtttt tcaaaaactt tctgatttga atatcgatcc tgcttcatta
    28081 atccaaaccg gaaagcttac aacaaaacga gctgaattcc ctattgaaga aggactttta
    28141 gctattgatg aaagctgggg agacaatcta cacgattttg aactggaact agaggtaggg
    28201 gatgcatctg tgggaaaaat tgcttttata aattttttaa aacgtttttc tttaccttat
    28261 cgtcctgcta agaacaagat ccaacgtatg cttgaagcta aaaattagaa acctttcatt
    28321 ttcacaaggc acttgagttc atttttttac ttttttctgt taagttatag gatgtgaaag
    28381 aatctagtca ctagttgtat agaatctatt ttgggggaga ttcatatgat cgaaatctat
    28441 ttatttgtta atcctttagg ggaatactgt ttcgaaatgg aacaacagtt attacaattt
    28501 atcgaagaag agtacgggac accatcaaaa gaaaagatgc aatttcgctt tcttcctttg
    28561 gtcaatttgc agacaattgg ggatgtcatg caacaaaaag gaatttctca gaacaatctt
    28621 gaggaacgta atcacttatt ctcaatgact tattctgcag cattggactg caaagcggcg
    28681 cagtttcaag gaaagaaaaa aggccgccgt tttttgatca aattgcaaga agcagtcggc
    28741 tgtaatgaca taccatattc tcaagaactt gctgaatcca tatttgaaga aatcggcggc
    28801 gatttgaata tgtttaaaga agatcgtcag tctgacttcg ttaaagaagt attcttttct
    28861 gatcaaaaaa ttgctcggga aatgggcatc acaaaacacc cttctgcagt cgtttacaat
    28921 tatgcctgcg accgtgattt tggtgtttta gtagaagtaa aaggtacaag tagcctttgg
    28981 agaatcacag agctgtgtaa aacaacagat aactcatatc aagtttttaa tggtgaacat
    29041 ttacatacaa atgattctca gttccattca agaactagcc atttacactt gctttctaat
    29101 taaaa
//
LOCUS       DAPBBR010000033        28599 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPBBR010000033 DAPBBR010000000
VERSION     DAPBBR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.033"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            237..1877
                     /locus_tag="RD488_001646"
     CDS             237..1877
                     /locus_tag="RD488_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDT7657724.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="RD488_001647"
     CDS             2031..3353
                     /locus_tag="RD488_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HDT7657725.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="RD488_001648"
     CDS             complement(3415..3846)
                     /locus_tag="RD488_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7657726.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="RD488_001649"
     CDS             complement(3910..4746)
                     /locus_tag="RD488_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDT7657727.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4936..5238)
                     /locus_tag="RD488_001650"
     CDS             complement(4936..5238)
                     /locus_tag="RD488_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDT7657728.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="RD488_001651"
     CDS             complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="RD488_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDT7657729.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5692..5958)
                     /locus_tag="RD488_001652"
     CDS             complement(5692..5958)
                     /locus_tag="RD488_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDT7657730.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6212..6937)
                     /locus_tag="RD488_001653"
     CDS             complement(6212..6937)
                     /locus_tag="RD488_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDT7657731.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7303..7373)
                     /locus_tag="RD488_001654"
     tRNA            complement(7303..7373)
                     /locus_tag="RD488_001654"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7339..7341),aa:Gly,seq:ccc)
     gene            7490..8242
                     /locus_tag="RD488_001655"
     CDS             7490..8242
                     /locus_tag="RD488_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7657732.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8258..8737
                     /locus_tag="RD488_001656"
     CDS             8258..8737
                     /locus_tag="RD488_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7657733.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8988..10568)
                     /locus_tag="RD488_001657"
     CDS             complement(8988..10568)
                     /locus_tag="RD488_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDT7657734.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10561..11304)
                     /locus_tag="RD488_001658"
     CDS             complement(10561..11304)
                     /locus_tag="RD488_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657735.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11480..12256)
                     /locus_tag="RD488_001659"
     CDS             complement(11480..12256)
                     /locus_tag="RD488_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7657736.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12504..13340)
                     /locus_tag="RD488_001660"
     CDS             complement(12504..13340)
                     /locus_tag="RD488_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HDT7657737.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13351..14280)
                     /locus_tag="RD488_001661"
     CDS             complement(13351..14280)
                     /locus_tag="RD488_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDT7657738.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14472..14825
                     /locus_tag="RD488_001662"
     CDS             14472..14825
                     /locus_tag="RD488_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7657739.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14899..15555)
                     /locus_tag="RD488_001663"
     CDS             complement(14899..15555)
                     /locus_tag="RD488_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7657740.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15781..17715
                     /locus_tag="RD488_001664"
     CDS             15781..17715
                     /locus_tag="RD488_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7657741.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17801..19024)
                     /locus_tag="RD488_001665"
     CDS             complement(17801..19024)
                     /locus_tag="RD488_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7657742.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19018..20916)
                     /locus_tag="RD488_001666"
     CDS             complement(19018..20916)
                     /locus_tag="RD488_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HDT7657743.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(20910..22028)
                     /locus_tag="RD488_001667"
     CDS             complement(20910..22028)
                     /locus_tag="RD488_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7657744.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22111..22944)
                     /locus_tag="RD488_001668"
     CDS             complement(22111..22944)
                     /locus_tag="RD488_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7657745.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22937..23854)
                     /locus_tag="RD488_001669"
     CDS             complement(22937..23854)
                     /locus_tag="RD488_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7657746.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24081..25205)
                     /locus_tag="RD488_001670"
     CDS             complement(24081..25205)
                     /locus_tag="RD488_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7657747.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25388..26296
                     /locus_tag="RD488_001671"
     CDS             25388..26296
                     /locus_tag="RD488_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657748.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26437..28050
                     /locus_tag="RD488_001672"
     CDS             26437..28050
                     /locus_tag="RD488_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7657749.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         8889 a         5621 c         4868 g         9221 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcattgg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaatgta ttgaatactt cttcgatcat
     4981 atcccattct gcgtctgttt cgatttgttc taactcgcct tctgttccat cttcgttttc
     5041 gatgtatgca taagcttgta attctacatc ttcatcttct gaaacaccag ctggatataa
     5101 aagaacatag ttacgtccaa attcttcttg tccgtcaact gttagcaaga tttcgtataa
     5161 tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg tgtccttcgt gttcgtggga
     5221 atggttatgt tctgtcataa gattacctct tttcttttta ttattaaaat aattgcttac
     5281 ctgagccgtc taaataattt tgtaaaatca tcacagctgc taatttatcg atgacttttt
     5341 ttcgtttcgc tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg
     5401 ttagtcgttc atcttgataa tcaaccggca aggagaatag ttctttgatc ttctctccat
     5461 atgacatgga agcttctgcc cttggtccga tggaattgtt catattctta ggtaatccaa
     5521 ctacaaaacg gtctacttcg tactgcgcca ctaattcctt caaccgatca aaaccaaact
     5581 cttcttctgc ctcattgatt cgaatgattt ctactccttg agctgtccag ccaaagggat
     5641 cgctcacagc aacgcctact gtcttagaac cgacatccaa gcccattact ctcataaatt
     5701 cactccatga tttgagaggt agtctttgac aattacttcc atgatttcat cgcgttcgtg
     5761 acggcgaatc aaatttcgtg catcacgata acgaggaatg taggccgggt ctccagaaag
     5821 caagtagccg acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac
     5881 aatcgctaat gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt
     5941 ttcatctgta aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt
     6001 ctacaccctt attttactcg aagaaaggga aaactacaaa caaatattcc aaacttctga
     6061 ataaattaag aaacacgatt tgtctgattt ttcctttttt ctgtggcttt ttcaaaagcc
     6121 ctctttccat aaagtatacg ctatatttct ttgaaagtat gtttttacac aattttttca
     6181 taaagttcat aaaaaattcg aattgctgct actaattttt cgttttcgtt gcttgccctg
     6241 tctcataatt gatggtgtag ccatcttgaa cattgtagat aaagacattg aattcaattt
     6301 ttttgtcttc aatgctttct gcttccaact gcacacctct tgctaccagt tcatttccct
     6361 cgaaatgagg agtgacacga tagcgtacat gatgatttgt ttccttgata tatgccgcaa
     6421 tatcattttc gtgggcaagc atgtacggag cattcaacga acgtgtccct gtcattaagt
     6481 ttttaatgtt attattttga ccagtcaact ggaaaccaat caaatggctg cggttgtata
     6541 accattgtcc gtcacttaat ttcttttgtt tccaacctgt cggatcaata tacaaaggtt
     6601 ctctcttttc agtaggaaac aagtcttttc ccaacatcgc attggcttgt cctactctgt
     6661 tcaatttgtc tatatttgaa tagctttccc atgtcccttt ggaaagacta agatcctctt
     6721 ttgtaaactc cggctgattc ccattgattt ctatttcttg atgttttcca tcatattctg
     6781 gcacatccgc tacttgagaa gcttgcggtg tggaatcaaa aatggttgta atttgttgga
     6841 agatatctga atctttttgt gtggtggaaa taccgagtgc ccctgcaatc acagcagcga
     6901 cgatccccac gatcgccttg gttgtttttt tgctcatttc tttactcctt tactaacagt
     6961 tccctaaatc ttaacatatg ttcccctata aataaatact ggaaagaaat agaaacagta
     7021 aaaaaataaa accagttttt agacggctta agaatacaaa aaaagagacg gattcatcgt
     7081 ctctactcaa tcacaaaaca ctatttacaa ggtatttatt atcattcaaa aaatttttct
     7141 taatactcaa aactaaacgg cttctgtacg acctcttggt aaacagtgtt caaaagcttg
     7201 catctgcggt aataagtcca accaagtcaa aaacataaga agcttttttg cttgactatt
     7261 cttattactt gatgcagggc agctttttca cagcctcttt taagcgggtg acgggaatcg
     7321 aacccgcgac atcagcttgg gaagctggga ttttaccact aaactacacc cgcgatacaa
     7381 aaacagtata cgcctctttc actccttcct caagtttttt tattctttac gcttccgata
     7441 tgttttgtag taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa
     7501 agaattagat ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa
     7561 tgcggagatg tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt
     7621 ccgtttggtc agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac
     7681 catccgaatg gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa
     7741 tgatctttca cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact
     7801 gcaagcaatc gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc
     7861 agtgatcagt ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac
     7921 tttagtcatt ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat
     7981 caaattttta tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt
     8041 acgttttggc ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt
     8101 tcctggagtt caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg
     8161 agtttctcgc ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt
     8221 tattttccag cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt
     8281 ttcttttagt tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc
     8341 attgatttgt tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca
     8401 aataggcgga tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag
     8461 cgatcttttc tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt
     8521 tcctctagtc cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta
     8581 tcgagaagcg gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg
     8641 tcttgtatta tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc
     8701 aatcatgatg aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt
     8761 tgtgaaagag acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt
     8821 aaccgcagga gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt
     8881 ctcacatttt tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat
     8941 ctgtaaaaaa ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt
     9001 ttccaaaacg ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg
     9061 atcacaggaa tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg
     9121 ataagaataa tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct
     9181 gaacctctgt taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct
     9241 ctagcgaaat aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta
     9301 gggataaaaa acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt
     9361 aaaaaactct gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag
     9421 attggcaaag aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata
     9481 aaagaagtct gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg
     9541 attaacttat tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata
     9601 aaaatgattg gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt
     9661 actaattgag cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt
     9721 ctttttattt tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc
     9781 agctgtttta cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat
     9841 aaaccttgtt gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc
     9901 ggatgccgat ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt
     9961 ccagcaaatg cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt
    10021 tttttaaaca ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga
    10081 ataatcaaaa atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga
    10141 tcagctcgcc atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg
    10201 gtcaaagcaa ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc
    10261 aaaaatactt gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga
    10321 gttaaaccta acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca
    10381 aagttcatag caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga
    10441 ttttgagaca aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta
    10501 ttcgtgagct gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc
    10561 ttatacatac ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc
    10621 tagcgtttca tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc
    10681 acctttcttc aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt
    10741 agaaaaaatg actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa
    10801 tgctgcttga ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg
    10861 cagcaacgtg ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt
    10921 ttcattttga tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt
    10981 tttttgtgtg tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa
    11041 ttgtaaaaaa atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg
    11101 attttccgtc aatttcattc catctactaa aatcgttccc gatgatggtt caataatact
    11161 aactaaactt ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atccaaaaat
    11221 ttccccttgt cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt
    11281 acttacattg atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg
    11341 tacccttcgt tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa
    11401 cgactaggct gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag
    11461 atatgagtct ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct
    11521 ttagtttatc aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta
    11581 tttcgtttac tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat
    11641 ctttacataa atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga
    11701 gaatctcttc atctttcaat actaggccta ttttattttt ataacctggc atgctcatta
    11761 gataaaggat ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc
    11821 accttttttt cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt
    11881 ggatgctttt tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa
    11941 tctttcgatt aataacagtt attgctttat tcggatgaga cgttagataa acaattttac
    12001 acttttcatt cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca
    12061 aatcgatgtc taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa
    12121 caaattgtat aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc
    12181 tggattcttc caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa
    12241 atatacgcgt taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat
    12301 acaacttttc aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac
    12361 acctttgaaa ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa
    12421 atgaatacat catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag
    12481 ctatgtttat ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca
    12541 gagactttct cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa
    12601 tagtctgatt ggatggttcc ttctatttta taccattcat catttttaac cgttactcct
    12661 tccggcatat gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg
    12721 aatcggaaca agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca
    12781 tagctgattt ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct
    12841 aaatagtttt catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca
    12901 ttcatttggt ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat
    12961 tgtgtctgca tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg
    13021 gcttctacga tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc
    13081 aaagctagca gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga
    13141 tcgtgctcgt gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact
    13201 aaagccaaaa gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg
    13261 atatattgat cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat
    13321 aaaatcaaaa accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct
    13381 aagggcaatc agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat
    13441 cagtagattt ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt
    13501 gccgaacaga cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat
    13561 cgtaaaggcc aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag
    13621 cataattcta gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa
    13681 ataacgacct gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg
    13741 gatcagctga ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg
    13801 gtgattttct gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata
    13861 ggcaagccag acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc
    13921 catctgccaa gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat
    13981 cggagcagtc agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg
    14041 atgaacgatc ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc
    14101 agtaaaaata gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa
    14161 aaatacttgt aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat
    14221 aacgatcgat aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat
    14281 gagtttcctc ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa
    14341 aaaacaagtt gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt
    14401 gactttttct gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag
    14461 ggagaataaa aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt
    14521 catccgttgc cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc
    14581 cacgactaga ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg
    14641 aaacaccaga agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc
    14701 atcaaggaaa agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc
    14761 tactagatga actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa
    14821 aataatcgtt gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg
    14881 ttcaatcgct ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg
    14941 caagaaatag atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc
    15001 tgacggagca ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt
    15061 taactgattg actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat
    15121 ttgttggatc ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac
    15181 gatgcgccca acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact
    15241 ttgatggaat ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac
    15301 atttgtcaat tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc
    15361 ataaccatac ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc
    15421 actatctact tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt
    15481 atttaaaatc cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat
    15541 aatatgatct ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca
    15601 tcatagcagt atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt
    15661 ctttattcat ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac
    15721 tactaattga aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc
    15781 atgatattat tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa
    15841 aacatacatt tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct
    15901 ggaaaatcga ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc
    15961 gctaaaaata aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat
    16021 gaaacagttt ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg
    16081 atgcgcgagc tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct
    16141 tatttaaaag aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat
    16201 gaaaatgaaa ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag
    16261 aaaatcgata ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg
    16321 caacaccctg acattttgat tctagacgaa ccaacgaacc atttagatat cgagacactt
    16381 tcctggcttg agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac
    16441 cgttattttt tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc
    16501 cattacaaag gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa
    16561 tggaaggctt atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg
    16621 aaccttgttc gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa
    16681 atggaccggc tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata
    16741 gaaaagcctt ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat
    16801 gtcaccttat ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta
    16861 ggtccgaatg gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt
    16921 atccgtggaa aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa
    16981 gctgatctgc atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact
    17041 ccagaaaaag agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa
    17101 aaaccaatcc ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg
    17161 atgaacaaag aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac
    17221 aaagaagtat tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat
    17281 gaccgatatt tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc
    17341 aaagtctatc taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc
    17401 gccgaattgt tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat
    17461 tattaccaaa gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag
    17521 gttgaagaag aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc
    17581 gcgccagaaa acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct
    17641 gctagacaag atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa
    17701 gaatatgaaa attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct
    17761 ttttttattt tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat
    17821 tactagtcat tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat
    17881 ttaccccatt atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt
    17941 ccgttgtagc atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata
    18001 agttcttttc tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca
    18061 tgatcaccat actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc
    18121 aataacaaat ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta
    18181 aatcaaaata tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc
    18241 atgcttggcc tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc
    18301 ttggttttcc atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta
    18361 ctaaataatc tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc
    18421 cagtttcttc actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc
    18481 taccttgttg tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc
    18541 aaaaacgctg aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc
    18601 ccgttatttt ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat
    18661 tagtgataat ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt
    18721 gttgaaataa aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc
    18781 cttctgtcca accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg
    18841 ggaattgata ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac
    18901 gctcgatctc attattccat tctttttcca ttaattcttt ataacattca tttatccatt
    18961 tttctggatg tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta
    19021 gcataatttt agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc
    19081 aaaatcaatt ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc
    19141 aaccactcct gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat
    19201 aaaagtgttt tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt
    19261 tcgtttaata gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct
    19321 atagttttcc ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc
    19381 aaaccctgtc tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg
    19441 ccagccttca aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt
    19501 agaggcaagt acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg
    19561 tccataggtt ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg
    19621 aatccctagc attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga
    19681 aaaaccaaat tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa
    19741 atttggccct aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag
    19801 caaattggct tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc
    19861 cgtccaatac tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa
    19921 tggagataac gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat
    19981 attcaggata cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt
    20041 gactaacccc ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga
    20101 ccaaaagctt gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc
    20161 atcttccgca aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat
    20221 ctggctaatg ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc
    20281 aaaaggatta taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag
    20341 ataacaattt tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc
    20401 aaatttttgg ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca
    20461 ttcatattca aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa
    20521 ttttttccat aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac
    20581 catacgctgg tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc
    20641 agcttttatt cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg
    20701 ccccgctccc cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc
    20761 taccccttga tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg
    20821 ttgatttatc tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg
    20881 atgtttcatt gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat
    20941 cgaagtaagc cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt
    21001 tctctatggt atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt
    21061 gcatagtgct tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat
    21121 cgtacagagg aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca
    21181 ctggtatcaa tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt
    21241 tcgattttct gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt
    21301 tttgtgtaac gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa
    21361 caagaattct cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca
    21421 tcaaattctg cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta
    21481 tctgcatgct gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa
    21541 tacagtaatg gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc
    21601 catgctacta aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt
    21661 aaccctagtt gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt
    21721 aagaataaaa aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat
    21781 aattgttctt gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc
    21841 tgccataaaa taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt
    21901 acgtctgtat attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat
    21961 tccgcatcta tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt
    22021 tcattcatgg atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac
    22081 gaactagatg gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc
    22141 cttaaattta gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa
    22201 aattagcata attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt
    22261 gataattaag ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata
    22321 ttgattccaa cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat
    22381 cggtacagcg attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc
    22441 catcagtgct gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact
    22501 ggcaatcgaa gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat
    22561 gtaaaataaa ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt
    22621 gaacaacagt ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga
    22681 actggctgta gctgaaactg tactgattac agcaataaca atcgaattcc aaataatcaa
    22741 gggataatta tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt
    22801 gaaattgatt ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata
    22861 taaatatggc atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct
    22921 gctttgtatc ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata
    22981 atataacaga tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca
    23041 tttcaaaact tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat
    23101 tggaagtccc aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta
    23161 aaactgtggc cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc
    23221 gaaatttcga tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa
    23281 gaccagctaa aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca
    23341 ttgatattcg tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat
    23401 tcaaaaatcc attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag
    23461 ccaccgttga tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta
    23521 actgtgctga attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg
    23581 atcctgccat gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga
    23641 tagctagata attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa
    23701 aagcaaacga gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg
    23761 tgaccaatcc ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct
    23821 ttattgtctt gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa
    23881 tcaccagtta attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa
    23941 ttttcaaaat cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca
    24001 tctgaataag tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt
    24061 tcatagtatt tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag
    24121 gccaatgagt tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct
    24181 gtcagcataa atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca
    24241 taaaaacttg atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc
    24301 agtggagcca tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca
    24361 taccagccgc cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca
    24421 ccgtagaaat gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc
    24481 gcttctttag tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg
    24541 gctagcatgt tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta
    24601 ccagtttttt cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct
    24661 tcaaaatcta cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta
    24721 aaatcactag cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat
    24781 ttttgatcat aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa
    24841 aaagcatctt gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata
    24901 tccggcatat cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc
    24961 gaagctacat tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt
    25021 gcagcatttt caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg
    25081 gcttttttta tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat
    25141 gcacttaagc tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt
    25201 ttcatgtcta tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtata
    25261 ttaacggaat tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct
    25321 tttcattttt gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga
    25381 aaggaaagtg gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact
    25441 aacctattcc atagataccc atcttcattt atctgctgct ccctattttc gactactaat
    25501 aaatgaaagc gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc
    25561 ttccctttta ttcattgata aacagcaaga agtccaaatc ttttctactc aaaaggaaac
    25621 acaaactttt atcattatcc agttttattt tgatgagcaa ttattagcac atattacggg
    25681 acaatctttt tctatagatc aagaaataac atctatcatt acttttctga aaaatgaaca
    25741 gttcaaaatt gattatctaa aacatagtaa gccagctatt tcctatgatc aggaaatcaa
    25801 ttcttttttc atactatgcc aacagatgag cattcatttg ctttccttat tagttactta
    25861 ttgtctgcaa aaaattcaat tgtcttcctt accaaggcat tatcaacagg aacttgcttt
    25921 attgacaata ccttcaaatg agaaagtcat tcctaaaaaa aagcatattc tttattcaga
    25981 tgaattagtt gatccaatca tacgatattt agaagaacat ctttcagaaa attttttgct
    26041 tgaacaatta gcccaaattt tttttatcag tccagccagc ttaaaaaaac attttagaaa
    26101 agtgaatgga aaaagtgtta ttagctattt taaagaacta aaaatggaaa aagcaaaacg
    26161 tctcgtgcta gaaaatgaat taacctatac agaaattgca gatatattag gatttcattc
    26221 gatccatcat ttttcttcag cttttaaaaa atatacaggg ttatcccctt caaagtatta
    26281 tctatcctta aaatagaaaa aaatttttag gttttatcca caaattattt ctctatattt
    26341 tctgtctatt caaaataaac aataattttc cggcacaatt atttgctgtt ttttaccata
    26401 acatagtacg atcaacgtag aaaaggagat gtttttatga aagttgttgt cattggcggt
    26461 gtagctggcg gtccttcatt tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc
    26521 attatctatg aacgcggaga aaatatttct tatgcaagtt gtgctttgcc ttattattta
    26581 ggaggtgtga tcactgaccg tgactcgctg atcgaacgta caccagaaat attgaaaaca
    26641 aaaaacaaca tcgatgtctt tactaaacac gaagtaacag caatcgatcc ttctactaag
    26701 cgattaacag ttaaagacct atccacaaat gaagaaataa aaacagatta cgataagttg
    26761 atcatctctt ctggtgctag accagattat ccggatattc ccggagtttt tgaagcagaa
    26821 aacggctttg tcctccgtag tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa
    26881 aaaaatccac aacatgtcgt cattcttggt gcaggtgtta tgggtctgga attagctgag
    26941 aatttcaagc atcgcggctt agacgtgact ttaatcgatc aattgccaca agtcgctttc
    27001 ccttatgatc cagaaattgc taatttagtt tatgacaaat tgctgaaaga aggattagcc
    27061 gttcatttag aaacaagagt tactgagatc cgtgataaag gtcgagaaat agtattatca
    27121 gatggctccg tcctttctgc tgatatgcta atttttgctg ttggtgtttc tccgaagaat
    27181 gaagtggtga aagcaaccgg catacaatta tcagatacag gtcagatcat tgttgatgac
    27241 cagttacaaa ccaatctgcc ggacatctat gcgattggcg atattatcga aacgactagt
    27301 gtagtgactg gtcagccgat ccaaagtatg ctttccagtg cggccaatcg tcaaggacat
    27361 atgctggcag atattttaaa tggtacgcct atgcgctatc gcggatatat tggtgcaggt
    27421 gtcgcaaaaa tctttgatca tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa
    27481 gcatcaggca taacaaatta taaaactgtt tttatcactc cctttgacca tgcctatttc
    27541 tatccagaag ctacaagatt aaatctaaag ctgatttttg atgcagatag cggtcgtatt
    27601 ttaggtggac aagcatttgg agaaaaaggt gtcgataaac ggatgggaga actttctgta
    27661 gcaatcaccg gaaacttgac agtctttgat ttgcctgatt tggagttgcc ttactctcca
    27721 ccgtattcta ctacccgtga cccgttgaat atagctggtt atgtcgcaat caatcaaatg
    27781 acgaatatcg tagaaacgat caaagcaagt gatatacccg aaaacgattt gaaagaagcg
    27841 ttctttttag atatacgtga acctaataaa gcaccttctg gcagtatctc ggcaacaaaa
    27901 aatattccaa tgaatgagtt acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt
    27961 tacattactt tcagaagagg attgaatact tatacttctg cccgaatctt ggcaggtttg
    28021 ggtatcaaag cgattttgat tgaagaataa aaaaacgacc gcggtgggta gccgcggtct
    28081 aggagttatt tttacttgag gagtaaaaat gaaaaagtat atagggttgt tggttggtat
    28141 gtatatagaa tagaagataa atgtgaagaa attgtgcatt atttcttcac atttattagg
    28201 ttatagttta agaaagttta aacattgcgc aatttaatta ttttagctgt ttcttttcat
    28261 aaaaaaacat gttgtgactc tgagacaaat catagtccat agtgatgtct ctagagtaac
    28321 tacgcctaat attacgaggc atcatattaa tctatcagca ctagtaccta aactagcatc
    28381 cctttcgaat attttttctt atataataaa gtttgctttc actcctctaa tctcaccaaa
    28441 tcgactggct tgcgttgtgt gatactagga actgattggt ttagaacgac ttttctattg
    28501 taatcatatt tttcgccatc ctcgttgtct tctaatcctt caatgaatga tccctaatgt
    28561 gtgtattaaa taatttaatt tttttgttcc tatttattt
//
LOCUS       DAPBBR010000034        28077 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPBBR010000034 DAPBBR010000000
VERSION     DAPBBR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.034"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            158..2692
                     /gene="secA"
                     /locus_tag="RD488_001673"
     CDS             158..2692
                     /gene="secA"
                     /locus_tag="RD488_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDT7657750.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            2818..3919
                     /gene="prfB"
                     /locus_tag="RD488_001674"
     CDS             join(2818..2889,2891..3919)
                     /gene="prfB"
                     /locus_tag="RD488_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDT7657751.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4024..4710
                     /gene="ftsE"
                     /locus_tag="RD488_001675"
     CDS             4024..4710
                     /gene="ftsE"
                     /locus_tag="RD488_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDT7657752.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4694..5587
                     /locus_tag="RD488_001676"
     CDS             4694..5587
                     /locus_tag="RD488_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657753.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            5739..7187
                     /gene="cls"
                     /locus_tag="RD488_001677"
     CDS             5739..7187
                     /gene="cls"
                     /locus_tag="RD488_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7657754.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            7524..8381
                     /locus_tag="RD488_001678"
     CDS             7524..8381
                     /locus_tag="RD488_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDT7657755.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8496..9416
                     /gene="pstC"
                     /locus_tag="RD488_001679"
     CDS             8496..9416
                     /gene="pstC"
                     /locus_tag="RD488_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDT7657756.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9416..10300
                     /gene="pstA"
                     /locus_tag="RD488_001680"
     CDS             9416..10300
                     /gene="pstA"
                     /locus_tag="RD488_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDT7657757.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10315..11121
                     /gene="pstB"
                     /locus_tag="RD488_001681"
     CDS             10315..11121
                     /gene="pstB"
                     /locus_tag="RD488_001681"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7657758.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11137..11895
                     /locus_tag="RD488_001682"
     CDS             11137..11895
                     /locus_tag="RD488_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7657759.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11908..12585
                     /gene="phoU"
                     /locus_tag="RD488_001683"
     CDS             11908..12585
                     /gene="phoU"
                     /locus_tag="RD488_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDT7657760.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            12808..13839
                     /locus_tag="RD488_001684"
     CDS             12808..13839
                     /locus_tag="RD488_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7657761.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            13836..14603
                     /locus_tag="RD488_001685"
     CDS             13836..14603
                     /locus_tag="RD488_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7657762.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            14703..16271
                     /gene="liaX"
                     /locus_tag="RD488_001686"
     CDS             14703..16271
                     /gene="liaX"
                     /locus_tag="RD488_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HDT7657763.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16568..16888
                     /locus_tag="RD488_001687"
     CDS             16568..16888
                     /locus_tag="RD488_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HDT7657764.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            16888..17238
                     /locus_tag="RD488_001688"
     CDS             16888..17238
                     /locus_tag="RD488_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDT7657765.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            17405..18343
                     /locus_tag="RD488_001689"
     CDS             17405..18343
                     /locus_tag="RD488_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDT7657766.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18358..19188
                     /locus_tag="RD488_001690"
     CDS             18358..19188
                     /locus_tag="RD488_001690"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDT7657767.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            19232..20257
                     /locus_tag="RD488_001691"
     CDS             19232..20257
                     /locus_tag="RD488_001691"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7657768.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20272..21210
                     /gene="galU"
                     /locus_tag="RD488_001692"
     CDS             20272..21210
                     /gene="galU"
                     /locus_tag="RD488_001692"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7657769.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            21335..21775
                     /locus_tag="RD488_001693"
     CDS             21335..21775
                     /locus_tag="RD488_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDT7657770.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            21778..22380
                     /locus_tag="RD488_001694"
     CDS             21778..22380
                     /locus_tag="RD488_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7657771.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(22443..23546)
                     /locus_tag="RD488_001695"
     CDS             complement(22443..23546)
                     /locus_tag="RD488_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7657772.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            23756..24757
                     /gene="ccpA"
                     /locus_tag="RD488_001696"
     CDS             23756..24757
                     /gene="ccpA"
                     /locus_tag="RD488_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDT7657773.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            25112..25507
                     /locus_tag="RD488_001697"
     CDS             25112..25507
                     /locus_tag="RD488_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657774.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            25507..25758
                     /locus_tag="RD488_001698"
     CDS             25507..25758
                     /locus_tag="RD488_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657775.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            25801..26196
                     /locus_tag="RD488_001699"
     CDS             25801..26196
                     /locus_tag="RD488_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657776.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            26193..27449
                     /locus_tag="RD488_001700"
     CDS             26193..27449
                     /locus_tag="RD488_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HDT7657777.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            27461..27784
                     /locus_tag="RD488_001701"
     CDS             27461..27784
                     /locus_tag="RD488_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657778.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            27777..28043
                     /locus_tag="RD488_001702"
     CDS             27777..28043
                     /locus_tag="RD488_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657779.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT         9444 a         4825 c         6070 g         7738 t
ORIGIN      
        1 gagtttcctc ctcttttaga tgaaatatga ataaattatg aagttcttac tttaatacgc
       61 ttaagatatt tcaattatct ataactaatg ataaaatgaa aagtaaagtc tacatagtct
      121 ggataataca cagaaggaaa aggagattac acaacgcatg gccaatttga ttcgttcact
      181 tatcgaaaac gataagaaag aactaaaacg tttagatagc attgcaaaaa aagttgaagc
      241 atacgctgac caaatggcag cattaactga tgaacaatta caggcaaaaa ctgctgaatt
      301 caagggcaga taccaaaaag gagaaacatt agatcaatta cttccggaag cttttgcagt
      361 cgtccgagaa gcagcaaaac gtgtattggg gttatatcca taccacgtac aattgatggg
      421 tggaatcgtg cttcacgatg gaaatatccc tgaaatgcgt actggtgaag gtaaaacctt
      481 gaccgcaacg atgccagtat atctaaatgc tctgactggc gaaggggtac acgtagttac
      541 cgtcaatgaa tatttagcaa cccgtgactc gacggaaatg ggcgaacttt ataatttctt
      601 aggattaaca gtggggttga atatcaactc aaaatcttcg gatgaaaaac gcgaggctta
      661 taattgtgat atcacttata gtacgaataa tgaattagga tttgactact tgagagacaa
      721 tatggtcgtt taccgccatc aaatggtaca acgtccgctg aattatgcca ttgtcgatga
      781 agttgactca atcttgattg atgaagcgag aacgccgctg atcatttcag ggcaagcaga
      841 aaaatccaca gctttatata caagagcaga caacttcgtg aaacgtttga aagaagaaga
      901 agattataaa atcgatgtac aatcaaaaac aatcagttta accgaagcag ggatcgaaaa
      961 agcagaagaa acattcggtt tggataactt atacgacatt gaaaatactg cattgaccca
     1021 tcacttggat caagcattga gagccaacta tatcatgctt ttagatatcg attatgttgt
     1081 ccaagacgga aaagtactga ttgttgacca gttcactggt cggatcatgg atggacgccg
     1141 ttattcagat ggacttcacc aagcaatcga agctaaagaa ggcgtagaga tcgaagacga
     1201 aacgaaaacc atggcgacga tcactttcca gaactatttc cgtatgtaca agaaacttgc
     1261 gggaatgact ggtacagcta aaacagaaga agaagaattc agagaaattt ataacatcca
     1321 agtataccag attccgacaa atcgtccggt tatccgtgat gatcgtccag atttacttta
     1381 cccaacatta caaagcaagt tccacgctgt cgtgcaagat atcaaagatc gctaccgcaa
     1441 aggtcaacct gtgttagtcg gaactgttgc ggttgaaaca tctgagttat tatcagatat
     1501 gctgaatcaa gaacgtattc ctcatgaagt gctgaatgcg aaaaatcact ttaaagaagc
     1561 agagatcatc atgaatgctg gtcaaaaagg tgctgtgacg attgctacca acatggctgg
     1621 tcggggaaca gatatcaagt taggacttgg ggtaagagaa cttggtggtc tagcagttat
     1681 cgggacagaa cgacatgaat ctcgtcgtat cgataaccag cttcgaggac gtgcaggacg
     1741 tcaaggagac cctggtatgt cacaattcta cttgtcattg gaagatgatt tgatgaaacg
     1801 attcggttca gaacgaatca aagctttctt agatcggatg aagatcggtg aggaagatgc
     1861 tgttatccaa agcaagatgc tgacgaaaca agtagaatct gcacaaaaac gtgtagaagg
     1921 aaataactat gacacacgta aaaacgtctt acaatacgat gatgtgatgc gtgaacaacg
     1981 tgaagtaatc tataaacagc gacaagaagt aatcatggaa gaaaaaagct tatccaagcc
     2041 actaatgaac atggtcaaac ggacaatcag tcgtgtagta gatgcgcata cacaattaga
     2101 gaaagaaaat tggaatttgg aaagtatcat cgattttgcc ggcagtactc ttgtccatga
     2161 agatagtatt actcttgcag atatcgaagg aaaaacatct caggagatca aagagtatct
     2221 aaacgaacga gcacaagaag tatttaatac caaagcggct caactaaatg gtccagagca
     2281 actgttggaa tttgaaaaag tcgtgatctt gcgtgttgtg gactctaaat ggacagacca
     2341 tattgatgca atggatcaat tacgtcagtc aatcggctta cgtgcttatg gacagaacaa
     2401 tccattagtc gaatatcaaa cagaaggcta taagatgttt gaagatatgg taggcgccat
     2461 cgagtatgaa gtcactcgaa tctttatgaa agctgagatc cgtcaaaacg tacagcgtga
     2521 acaggtttct caaggaacag cttctcactc agaagacgga gatgccaaag aaaatagtaa
     2581 tactagcgcg aaaaaacagc caatccatgt gaacaaggtc ggaagaaatg atccttgtcc
     2641 ttgtggaagc gggaaaaaat ataagaactg tcatggaaaa aatgcaaact aatttctgac
     2701 agcaggattg gtgagacaaa ttcttttttt aagaattcgt ctcaccttct ttctgttatt
     2761 tgctgattct gttagactag atataatgaa aaaagtatag tgaaagaagg aaaaaacatg
     2821 gaaatatccg aaattcgaaa tctcctgaca gaaatgcagg aaaaggtcac aagtttcagg
     2881 aggtctcttt gacttagatc agctggaaga agacatcgcg gaagcagaag caaaaatggc
     2941 tgaacctggt ttttgggatg acagcgaagc cgcacaaaaa gtgatcagcg aaaataacgc
     3001 taataaagaa acctatgacc aattccattc tcttgccgaa gaactagaag aaatcgaatt
     3061 gatggtggag atgctgcaag aagaacctga tgcagcaatg caagaagaag cagaaacacg
     3121 tatcaatgca ttagatgaaa aaatgaagac gtatgaatta tctatgctgt tagacggacc
     3181 ttatgatcga aacaatgcga tcgtcgaatt gcatccaggg gctggcggaa cggagtccca
     3241 agactggggc agcatgcttt tacgtatgta tacacgttgg gcagagcagc atggctatca
     3301 agtagaaaca ctagattatc aagcaggtga tgaagcaggg atcaagagtg tgaccctgct
     3361 gattaaagga cataacgctt ttggttatct aaaatcagaa aaaggtgttc atcgccttgt
     3421 acggatttcg ccttttgact cagcgaaacg acgtcatact tctttttgtt cggtagatgt
     3481 gatgccagag cttgatgaaa cgatcgatat agaaatcaat ccagatgatt tgaaaatcga
     3541 tacgtaccga gcaagtggtg caggtggtca gcacatcaat aaaacagaat ctgctgtacg
     3601 gatcactcac ttgcctacag gaacagtagt agctagtcag gcacaacgct cacaattgaa
     3661 aaaccgtgag caagcgatgg ggatgttaaa agctaagctt tatcaattag aagtggaaaa
     3721 gaaagaacaa gaagcagctg cacttcgagg agaacaaaaa gaaatcggct ggggttcaca
     3781 gatccgttct tatgttttcc atccctattc tatggtaaaa gaccatcgga caaacgtaga
     3841 gacaggaaat gtccaagcag ttatggacgg tgaccttgat ttatttattg acggctattt
     3901 aaaaatgcat ctacaataag aactcattgt taaattgaaa taaaattgta agattttgca
     3961 agcatgttga aacattgcca tgctataata gctaaagact gaaaaagata tggagagaac
     4021 gccatgattg aaatgaagga tgtaatgaag aagtactcaa atggtacgac cgctatccgc
     4081 aatctctcga ttgtcatcga acaaggagag tttgtctatg tggttggtcc gtctggagcc
     4141 ggtaaatcta cattcatcaa attgatgtat cgagaagaaa aagcttcaaa aggaactttg
     4201 aacgtcgcag gtcatgatct aatagcaatc aaaaaccgcg aagttcctta tctacgcaga
     4261 gaaatcggcg tggtgttcca agactataaa ttattaccaa gaaaaacagt atatgaaaat
     4321 gttgcgtacg ctatgcaagt tatcggcaga aaacctcgag atatcaaaaa acgagtaatg
     4381 gaagtgctgg accttgttgg tttgaaacac aaagttcgag tctttcctag cgaattatcc
     4441 ggtggggaac agcaacgtgt ctctattgct cgggcaatcg tgaatacgcc taaagtactt
     4501 atcgcggatg aaccgacagg aaatctggat ccagaaaact catgggaaat catgaaatta
     4561 ttagatcgga tcaatgccca aggaactact gtcgtgatgg ctacacataa cagtacgatc
     4621 gtaaatacga ttcggcaccg agtaattgct atcgaaaacg gccgcattat tcgagatcaa
     4681 gcggaagggg aatatggata cgatgattag aacctttttc cgccatttat tagaaagtat
     4741 caagagtttg aaacgtaacg gctggatgac agttgcttca gtcagtgcgg taacgatcac
     4801 gttgacttta gtcggtgtat tcatggcagt tatcatgaat gcaactaaat tagctcagga
     4861 tatagaagga aacgttgatg tatctgtatt cgtagatatc ggtacaaaag acgaagagat
     4921 gaaaaagcta gaaaaagaat tgaatgactt agatcatgtt aaaaaagttg aattttcaag
     4981 caaagaacag gaattgaaaa aaatccaaaa cgaaatgggt gattcctgga aattgtttga
     5041 aggtgacaat aacccgttat atgatgtgta tgtagtaagt gctactgatc cttcttatac
     5101 aaaacaagta gcagaagaag cagcagattt gaagaatgtt tctcgttctg attacggtgg
     5161 agcttcctca gatcggattt tccaaatcgc tggtgcagtt cggacatggg gattagttgc
     5221 agcggcattg ctgctgttcg tagcgatgtt tctcatttcg aacacgattc ggatcacgat
     5281 tttgtctaga cagcgtgaaa ttcaaatcat gcgtttagtc ggtgcaaaaa atggatatat
     5341 tcgctggccg tttttccttg aaggtggctg gatcggtctg atcggtgcga ttcttccgat
     5401 tttgatcatc acatttggtt atgcatggtt tttccaattg atcaatccat cattattacg
     5461 ttcccattat tcattgattc gtccacaaaa tatcgtttgg aaaatcaatc ttttaatggt
     5521 cggcattggt gtgatcattg gttcacttgg ctcgatcatt tctatgagac gttttttgaa
     5581 attctaatac cacaatataa ataaaatgag aaagttggac agtttcgttc cagctttctt
     5641 tttttattgg ctaggagaat agaaggaagc ggcttttttc cctttacttt aaaaaacaac
     5701 ttgggtattc ttaagttggt agaagaagag gtgaagccgt gaaaattatc gttgacaatt
     5761 tttttacgat ccttttgatt atgaatattt tgctttcctt tatcatcgtt tttcgagaaa
     5821 gaaaggaaac tgctcaaaca tgggcatggc tgctcgtttt gatgttcatt ccagttgtag
     5881 gatttatttt atatattttt ttaggaagag ggatttccaa agagaaaatc tttgatttga
     5941 agatccaagg gaaaatcggt aagaacctgg aaattgaaga agacaaacag gcattgatgc
     6001 gagggcttta tcctcatccg cctactggac aagtagatgt gaaacaattg atctatatgc
     6061 tcacggtatt tgaaagtacg ctctatacga ctaaaaatga aatcacttta tttacagatg
     6121 gtcgtgaaaa attcgatgcg ctgattgaag atatcaagca ggcagaagac catatccact
     6181 tccagtatta tatttatcgc agtgatgcat taggtgaaga agttcgagat gcattgacag
     6241 aggcggcaag acgaggggta aaagtcagag tccttcttga tgcatggggt tccacacaag
     6301 tttcttccag cttttttcag aatttgaaaa aagcaggcgg agaagtcgca tttttctttc
     6361 ctctatttgt tccgtatatt aatcctcgga tcaattatcg caatcatcgt aaaatcgtag
     6421 ttattgatgg gaaaatcgga tatacaggtg ggttcaatgt tggaaatgaa tatctaggat
     6481 tggtaaagaa atttggttat tggcgagaca atcatttgcg tatttacgga gaagcggtgt
     6541 ataccttgca aaaccgtttt ttgatggact ggaattctca gcatacaaaa gaagtaggct
     6601 attctcccaa atttttcccg tccattcaca ctactggtga tatagctgtt caaatcgtga
     6661 caagcggacc agataccgaa catgaacaaa tcaaaatgac ttatttgaaa atgatttcgt
     6721 tagccaaacg ggagatattg atccaaacgc cttattacat accggatgga tcgattcatg
     6781 aagcactgaa gttggctctt ctttcaggcg taaaagttca tatccaaata cctaacaaac
     6841 cagatcatct tctcgtttac tgggcaacgt attctttcgc tgcagagctg atcgagtatg
     6901 gagcaaggat cgaaacatat gagaatggat ttattcatgc aaagacgatg attatcgatg
     6961 gtggcattgt ttcagttggc tcagcaaata tcgatgttcg ttcatttcgc ttggactttg
     7021 aggtcaatac actggtttat gatgaacgaa tggcttcacg tgtaagaaaa gctttttttg
     7081 aagactcgaa aatttctacg catctcacaa aagaaatgta tgaaaaccga ggaataatca
     7141 tcaagatgaa agaaggatta gcaagattga tttcgccgct cctttaaaac ataaaaagga
     7201 catgagaacc atcaacagat ggagatctcg tgtccttttc taacggggcc atttctgaga
     7261 gtacgtcaga aatggagaaa gcgtctcgca tgagcgaaat taactttggg gtatctcttg
     7321 ttttttgggg aaagcaagaa ataagctaat atatgctatt aaaagagaca catttcaaag
     7381 ccagtatagc atagaaactt ttaatgagat agtttttttt acaattatga gaatttattt
     7441 tgttatttaa tgattttgat tcgttttcat caagtaatga aaatgataaa ataaacatac
     7501 tttaggatta aaggagattt ctaatgaaaa aacttaaatt attcttacca ataataggat
     7561 tagccattct tttatcaggc tgttcaaagt ggattgatcg aggagaatcc attacggctg
     7621 ttggctcttc tgctttacag cctttagtag aaacagttgc tgaaacttac cagacagaaa
     7681 atcctggaaa attcatcaat gtacaagggg gcggaagcgg aactggtttg tctcaagtac
     7741 agtcaggagc agtcgacatc ggaaactctg atttgtttgc ggaagaaaaa tcggggatcg
     7801 atgcctcagc attagtcgat catcgagtag cagttgttgg gatcactcct attgtgaaca
     7861 aggatattgg cgtaaaagac atcagtatgg aaaacctgaa aaaactattt acaggcgaga
     7921 tcaaaaactg gagtgaagtc ggtggaaaag atcagccagt agttatattg aaccgcgctt
     7981 caggaagcgg aacccgtagc acgtttgaaa aatgggtatt ggacggagaa acagctgttc
     8041 aggcacaaga acaagattca agcggaatgg tgcgccagat cgttgccgac acacccggtg
     8101 caatcagcta tgttgctttt tcttatgttt ccgatgatgt agatacgttg aatgttaacg
     8161 gtgtagaacc gacagatgaa aatgtgacaa cgaacaaatg gacgatttgg gcatatgagc
     8221 atatgtacac aagagatcat ccaaaaaaac tgacaaaaga atttttagac tatatcttat
     8281 ctgatgaagt acaagataac atcgttggag aactaggtta tatccctgtt tctcatatga
     8341 aagtcgaacg tgattggcaa ggaaatatcg ttaaagagta atctttacac aaaatttaca
     8401 aacttagcta aacttttaca tgttattaaa accaaattga tgttcaattt gtacactgag
     8461 tgagtatgtt aaacctgatt aagggggagt catctgtgga agatgtgaaa aaagtattat
     8521 taacaaaatc aaaacgttca aaaatggaac agcgtggaaa attcatcagt tttttatgta
     8581 tcgcgctgat cgtgttggtt gtattatcta ttttttattt tgtagctagt aaaggattgg
     8641 ccaccttttt tactgataag atcaatgtat ttgattttct gtttggtaca gattggaatc
     8701 caagccaaat cggagcaaat gggaaaccaa tggtaggggc attgcctatg atcacaggtt
     8761 cgtttattgt gaccttttta tctgctatcg ttgccacgcc atttgccatt ggtgcagcag
     8821 tattcatgac ggagatctct cctaaaaacg gaacgaagat cttacagccg gtcatcgagc
     8881 tgcttgtagg tattccttct gtcgtttatg gttttatcgg tttatcagtt atcgtgcctt
     8941 ttgtcagaag tatttttggc gggacagggt ttggtatctt agctggtaca tttgtgttgt
     9001 tcgttatgat cttgccgact gtcacaacga tgactgttga tgcattaaag gcagtaccac
     9061 ggcactatcg ggaagcttca ttagcgcttg gtgccacaag atggcaaaca atctacaaag
     9121 tcgtgctacg agcagccgtg cccgggattt taacagcagt cgtttttggt atggctcgtg
     9181 cgtttggtga agccttagct atccaaatgg tcatcggtaa tgcagcattg atgccaacag
     9241 gacttactac tcctgcttct acattgacgt ccatcttaac aatgggaatc ggaaatacaa
     9301 tcatgggaac agttgaaaat aatgtgttat ggtcattagc gctgatcttg ctattgatgt
     9361 cattattctt taatatcgtg atccgtatga ttgggaagaa aggagagctg aaataatgaa
     9421 cgcaaaacgc tcagataaaa ttgctacagg tgttttatat atagtttcgg ggatcatcgt
     9481 attgatttta gcagctttac tactttatat cttagttcgg ggaataccgc acatttcatg
     9541 gtccttcttg accgaacctt ccaaagccta ccaagaaggt ggtggaatcg ggatccagct
     9601 atttaactcg atttatttgc ttttgatcac gatgatcatc agttttccta tttctttagg
     9661 tgcgggtatc tatctttcag aatatgctgg aaaaaactgg ctaacagatg tgattcgcac
     9721 gtcgattgaa atcttgagct cgttgccttc tgtcgttgtc ggtttattcg gtttcttggt
     9781 tttcgttatt caattccagt atggtttctc gattatttct ggtgcattgg ctttgactgt
     9841 attcaacttg cctcttttga ctagaacagt tgaggagtct ttacaagcgg tccattacac
     9901 acaacgagaa gcaggattgg ccttaggttt gtcacgctgg gaaacagtga tgaaagtggt
     9961 ggttccagaa gcgacaccag ggattttgac tggtgtgatc ctaagttctg gaagaatttt
    10021 tggtgaagca gctgcattga tctatacggc tggacaaagt gcacctgcgt tagattttac
    10081 gaactggaat ccattaagtg tttcaagccc gatcagcatt ttccgtcaag ctgaaacatt
    10141 agctgtccat atttggaaga tcaatacaga aggcacgatg cctgatggtg tttctgtttc
    10201 ggctggcgct tctgccgtgt tgatcattgc tgttttactg ttcaacttcg gcgctcgtgc
    10261 gattggcaaa cgattatacc gaaaaatgac ttcagcctaa ggagaagaag caaaatgaaa
    10321 aaatataact ggaatgaaac aaatgtcatc accatgccaa aagagaaaga agtagcacta
    10381 tatacggatg atatacatgt ctggtatggc gacaatgaag caatcaaagg agtggatctg
    10441 gaatttgaaa aaaataagat cactgcactg attggtcctt ccggctgcgg aaaatctacg
    10501 tatcttcgtt cgttgaatcg aatgaatgat gggatcgcta atacgaaaat cactgggaaa
    10561 atcatgtatc aaggcgtaga tattaatgcg cctcaagtgg atgtttatga gatgcgcaaa
    10621 cggattggca tggtttttca acgtcctaat ccgttcagca agtcgattta tgacaatatt
    10681 acatttgctt tgaaacagca cggcgaaaaa aacaaaaaga aattagatga aatcgttgaa
    10741 acaagcttga aacaagctgc cttgtgggac caagtaaaag acagcttgga caaaagtgcc
    10801 ttggctttat ctggcgggca acagcaacgt ttatgcattg ctcgtgcgat cgcgatgaaa
    10861 cctgatatct tgctgctaga cgagccggca agtgctttgg accctatttc gacaggaacg
    10921 gttgaagaaa cacttgtaaa cttgaaagaa gactatacga tcatcatcgt gacgcataac
    10981 atgcaacaag cagctcgtat cagcgactat actgcctttt tctatctagg aaaagtaatg
    11041 gaatatgaca aaactaacaa gatatttacc agaccaaaaa ttcaggcaac cgaagattat
    11101 gtgtccggtc attttggtta agacggaggc ctcaacatga caaaagaaat tatttcatct
    11161 aaagatcttc atctgtatta tggaaagaaa gaagcactaa aagggatcga tctaagtttc
    11221 aatcaagggg aaatcactgc gatgatcggt ccttctggtt gcggaaaatc cacttatctg
    11281 cgttctttga accggatgaa tgacctgatt ccgaatgtaa cgatcaccgg aagtgtttta
    11341 tataaagaca aagacatcta tggtccaaaa acagatgttg ttgaactaag aaaagaaatc
    11401 ggcatggtat tccagcagcc aaacccattt cctttttcta tctatgaaaa tgtcatctat
    11461 ggattgaaat taaaagggga aaaagataaa aaagtccttg atcaagtagt tgaagaaagc
    11521 ctgaaggcag cgtctgtttg ggatgatgtg aaagacaaat tgcataaaag tgctttatct
    11581 ttatccggcg ggcagcagca gcgtgtatgt atcgcacgtg ttttggcagt taatccggaa
    11641 atcatcttat tggatgaacc aacaagtgcg cttgatcctg tttctactgg gaaaatcgaa
    11701 agtatgctgt tagaattaag agagcggtat acgatgatca tcgtgaccca taatatgtct
    11761 caagcttcac gtatttcaga taagacggca ttctttttag atggtcactt gatcgaatac
    11821 aacgatacga agaagatatt catgaatcca gaaaaacaag agacagaaga ttatatttca
    11881 ggtcgatttg gataaggagg aaacggaatg ctacgtacac aatttgaaga agaattgctg
    11941 aatctccata atcagttcta cgaaatgggg atgatggtga gcagcgccgt gcacaagtca
    12001 gttcgtgcat acatcaaaca cgataaaatc ttagcccaag aagttatcga aaacgatata
    12061 aatatcaata acatggaaac acgcttggag aagaaaagtt ttgaaatgat cgcattgcaa
    12121 cagccagtta caactgattt gcgtatgatc attacggtca tgaaagctag ctcggattta
    12181 gaacgtatgg ccgatcatgc ggtgtctgtt gctaaatcca cgattcgcgt aaaagggcag
    12241 acgagaatac cggaaatcga aaaagagatc tccgatatgt ccgattatgt gaaaaaaatg
    12301 gtggacaacg tcctagttgc ttatgtcaaa acagacgaaa aagacgcacg tacgatcgcc
    12361 aatatggatc aaagagtcaa tgactatttc aatcgaatct ataatgcaac aatcaaaaat
    12421 atgcaggaaa atcctgagac agtcatcagt ggaacagact acttgaatgt tgccagttat
    12481 ctagaacgga tcggagacta tgtgacaaac atctgtgaat ggatcgtcta cttggctaca
    12541 gggaaaatca ctgagttaaa tacgaaccac aatgagattt tctaaactga agctgtgatt
    12601 atgccgtttg tttatgaaaa gaggttgtga aaaagctgtt ctacatcaag taataagaac
    12661 agtcaaacaa aaaatagctc ctcatatttt tcgtttggct ggacttatta ccgcagatgc
    12721 aagcttttga acaccgttta ttcgggaaag ggtttgtgac aaaacatgtc acaaaccctt
    12781 ttcatcattt catagaaagg ataaagaatg caaaaaaaaa ttagcatcat cactatattt
    12841 tttatttgtg tgcttacttc atgggttatt cagcatcaag ccgctttata tgaagtacct
    12901 gtcatcgaga tagaaaaagt acgaataaaa gaggatcatc aattgattac aggaaaactg
    12961 atgaactcgg atcaaaaagg agaatcgatt tatttatcgg ttccttatca aaaaaatcaa
    13021 atagaaacag caaatataaa agcgagacaa atgtatctag tccaaatgca tggagatgaa
    13081 tggcagctag tagcaaaaaa aaatgatggc tggcttttct tcttcacaag tatcttcatt
    13141 ggcgccatgt tgcttattgg cggaaaacag ggtctatttg ctttaggaag tctcatcatc
    13201 aatatcgttt tacttttact tttgttgctc atctttacta aaacagaagg gatttctcta
    13261 ttaaataaat ctatcctgtt cgtcgttata gggatgatta ttagcatatt ggctttagat
    13321 ggatggaata gaagcagtat aatcaaaatt tcagctgcag ttacgagtgt ttttttagca
    13381 ttttttattt gtcttttgac aatgaatcat tggaaagacc aaggactgcg ctatgaggaa
    13441 ctgaattatc tgacacgacc gtatcgttct gtttttcttt ctagcgtact gattggaaca
    13501 gctggaggaa cactcgatac cgttatcaca gtcattgcga cattagaaga attgactaag
    13561 cgacaaccag aaataacagc gaaacagtta tggctttcag gaaggcaagt gggtcgagat
    13621 gtgattggct cgatgaccaa tatccttttg ttcgtctata tcagtgggtc agttccatcg
    13681 cttcttttat atttaggaaa tcaatggtct ttcaaagaaa cgatagaaca gcatttatca
    13741 ttggaatttt tacgcgtcat tgctggcagc ttaggaatag tattatcgat ccccatctcg
    13801 gtcctctttt ttctgactgt aaggaggctg aaacgatgaa tgtacttatt atacttgttg
    13861 ggattttagc aatcagcgtg ctacttattg gcggtacgca aggtatgtat attcttttag
    13921 gcttattcat caatttaggg atctttttcc tgttgttatt cggttatcat cagaagtggc
    13981 cgatactggc attgtcggtc ataggatttt tattgattgc tgtggttatc ttatttttta
    14041 tcaacggtta taatctaaaa atgcgtgcag cttttgtgag tatactgatc tttttatttt
    14101 gtttcctact attgcttcct atcactgatt ttttagcgat ccaaggtttt acatcggtag
    14161 aactagaaga attatctggc ttagataaga ctttagcgat tgattttaga ttacttacga
    14221 gatcgttgct tctgattagt cttagtggtg ctgttttaga tgcgagtgta gcaatttcta
    14281 gtgggacatt cgaagtatat caggcaaatc cgcaattatc tttttaccaa ttgcgccatt
    14341 ctagtttcgc tattgctaaa aaaatattgg cgtcaacagt aatgacactt ctttttgcat
    14401 tcatgggaag ttctttagcg ttgatcctct ggtttattga tttagacatt ccttttcagc
    14461 aagtgatcaa tgaaaaatca tttgttctag aatatacgat ggctattctt accacattgt
    14521 ccgcactaat tgttcttcct ttaacctgcg tgactacagc atatctcttt acaaaaaaga
    14581 aagaacaact caagatggag taaaagttac aacttaagtc ctatgacatt tttactgaat
    14641 cagtgcataa tatggatgta aggaaaagct tgcaaacaat tttgcttaag gaggcaattt
    14701 ccatgaaaga aagagaacgt attttagatt tagtgaaaaa aggaatcctt tcgactgaag
    14761 aaggcttaga tttattagaa agcatggcaa ctgaaaaaga cgaaaagcaa atcaaaaaag
    14821 aagcagacaa ggtaactgct agtcataaag aaaaagataa ggcaagtcaa ttgatcgata
    14881 aacttgaaaa cggcgaagaa gaaatttctg agccagttga tccaaaggaa agagaaagac
    14941 aagatcaaga aaacttagaa aagatcttag atgaactagc aactgaagcg aataaaactt
    15001 cggcgcgtct agatgaagta aatgctcaat tcgctgacaa taaggcagca cgcaatgaga
    15061 aacaggaagc attgatgcag ctgaatacaa aagaagaatt aggcgagttg acagaagaag
    15121 aattagcaca gcgtcaggcg ttagaggcag aaatcaaaga gttagaagct agtggcgata
    15181 cactgttaga agaacaattg aaattagaag cagaattaaa agatatccgt aagaatcaat
    15241 ggtctgagaa aaaagaaacg tttactgata agtttgaatt gccagatgat tggaaagatc
    15301 aagcaacaga tacactgaat caagtaggcg aaaaaatgtc agaagctgga tcacagttag
    15361 gcaaattctt gaagaaaaca ttccaaactg tttcagaaac agtgaatgac aacatggaat
    15421 ggaaagatgt cagcttacgt gtccctggga ttgcgacaac gaaatttgag catgaatttt
    15481 actatgaagc tcctgcagca agtatccttg atatcaaggc agcaaacgga aacgtgacgt
    15541 taaaaacgtg ggacagcaac gatgtgaaag ttgaagctaa gatcaaactt tacggaaaaa
    15601 tgggtgctga accatttgaa gcattctctg aacggagcca gattgaggtt aatgaagatc
    15661 atatctcctt ccaaattcca aataaacgtg tgcgtgcaga ccttgttttc tacttaccta
    15721 aacgagtata cgaccacgca gctattaaac ttctaaatgg caacatcatg attgaaacat
    15781 tggaagctaa agatatttat acaaaatcta cgaatggtaa catcatcgtg gaccaattaa
    15841 ctgcaacgat gctggaagta gaaggtgtaa acggcaatat cgatattcga aacgggaaca
    15901 tcttagattc tattatcgaa acagtaaatg gtacagtgac atttggtgcg acagcagaaa
    15961 atctttctgt gtctttagta aatggtgatg tacgtcttac gattaaagaa gataatttga
    16021 aaaaagtaga agcaagttca gtgaacggaa atgtcaaagt cgctttacca gatggcatcg
    16081 gtttggaagg acatgctaaa acaagtcttg gaagtatcaa tagccgtctg tccaattacg
    16141 aagtagttcg tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt cgtgtttcag
    16201 atgatgagat cgcgcaagtg caactttcaa cgacaacagg aagtatctat ttaaaagata
    16261 cagataaata aagaggttgt gaaagagatg ttcagccttg agcaataaga agcgattttg
    16321 taaaatagct tcccctattt tacaaaattg tgccttattg ccgatagtct atctcttgaa
    16381 caccgtttac caagagatta tgaacctgcc aattatcgcc gagtcacaag gaataatttc
    16441 agaaaaagct cgtcacgttt tatgaatatg gtaatttgtg accgagaatt ttgcagaaag
    16501 acaccgatta agaagaaggt tgtcacaacg attttcttca tttaaaatag tagaacagag
    16561 gtgagacatg atgaaaaaaa agttgacaaa atctaataaa aatgttgttt tgacagggac
    16621 tttagcagga ataggagaat acatcgggat tgatccgact gttatccgtg tgctttatgt
    16681 attcctgagc ttagttgctt ttggaagtcc aattatttta tacattttat tagctttgat
    16741 tatcccatct gcgcgttctg cacgaacaaa ctatggacat aacaatgcat attatgaaaa
    16801 aaacaattat cgtgaacaaa ctcgtgaaca aacaaaaaaa cgcaaagaag cggaaaaaat
    16861 cgatgatgac gaatggagtg acttttaatg tcgtactttc aacgtatttt agttaatacg
    16921 ttaacattca tatcattggc tgttcttttt cctgcgatgg tccatgtgag cagtatttgg
    16981 acggccgttc ttgccagctt cgtattgtct gtgttgaata tgtttgtcaa accgattttg
    17041 acgatactgt ccctgccctt tacattagtc acattgggat tgtttacgtt tgttatcaat
    17101 gcagcgattc ttaaaatgac ctcctttttt gtgggagcag aacattttag tttttcttca
    17161 ttcggtgcag cgttgttagt agctatcttg atgtcgcttg tcaatgtaat tgtcagcgaa
    17221 cataacagta gaaaataaaa gaaagctgtg ccgaactatc ggcgcagttt ttttatttag
    17281 aatcaggaat gcgttttcta ttacattggt aattaaataa aaacgttttt tttaattggt
    17341 agtacttttg gctagacaat gataaaatga tagagaacac tctaatagaa atgaggtagc
    17401 atgaatgtca gaagttgtaa aagttagcca attagtgaaa aaattatctt tggaaatcgt
    17461 gacaggcgac gagaaaagct tagaccgtgt catcgtaact ggggacatct cacgcccagg
    17521 actagagttg actggttatt ttaattatta ttcccataat cgtttacagc tatttggcag
    17581 taaagaaatc agttttgcgg aacggatgat cccagaagag cgtttgatca tcatgagaag
    17641 attatgtagt gaagatatgc ccgcatttat tatttcaaga ggattaccag ctccagaaga
    17701 aatgatccag gcagcaaatg aaaatgggat agctgtactg cgttctccca tctcaacttc
    17761 tcgtttatta ggagaattat ccagttattt agatggtcgc cttgcccctc gaacaagtgt
    17821 ccacggtgtt ttagtggatg tttacggatt aggtgtactg attcaaggtg acagtgggat
    17881 aggaaaaagt gaaacagcgt tggagttgat caaacgcggc catcgattga tcgcagacga
    17941 tcgagtagat gtttatcagc aagatgaatt aacggtgatc ggagaaccgc ctaaaatcct
    18001 ggaacatctg attgaaatcc gaggaatcgg gatcattgat gtaatgaatc tttttggtgc
    18061 gagtgcggta cgtggctcta tgcaagtcca gttggctgtt tatctggaag catgggcaaa
    18121 agataagaaa tacgaccgtc tgggctctga agacacgacc gttgaaatcg cggaagtggg
    18181 cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca tcattgaagt
    18241 agccgcgatg aatttccgtg cacgtacaat gggctttgac gcaacgaaaa catttgaaga
    18301 aagattaagt cgcttgattg aagaaaactc aggcaacgac tagcaaggag tgacaatatg
    18361 ttagcacaaa tcaatcgagt tgcttttgag cttgtaggga ttcctatcta ctggtatgca
    18421 ttgatcatcg tatcaggtat cattatcgct atgtggctta gcagcagaga ggctgttcgg
    18481 gtaggattaa aagcagatga tgtgacagat tttatgttgt ggggattgcc tatctccatt
    18541 attggcgctc gcttatatta tgttttattt gatcttcccc agtatatagc tgatccaatc
    18601 caaatattca atatccgttc aggaggctta gctatttatg gcggactgat tgcaggcgcg
    18661 atcacgctgt atttttttac taaatatcat tttatttctt tgtggacttt tttagatatc
    18721 gctgcaccaa gtgtattatt agcacaggca atcggtcgtt ggggaaattt catgaaccac
    18781 gaagcatatg gaccagacac gacgcgaagc ttcttagaaa gtctgcattt accgcaattc
    18841 atcattgata atatgtatat cgaagggatc tatcgtcaac caacatttct ttatgaatca
    18901 ctttggagtt tgattggatt tattttgctt ttgtttttac gaaagaaacc acaccttttg
    18961 aaaaaaggcg aagtcctttt atgttatcta atgtggtata gtttcgggcg tttctttatt
    19021 gaaggattac gtacagacag tctttacttt ttaggtgtga tccgtatttc tcaattatta
    19081 tctgctgtgt tatttgtcgg tacattgatt ctatttattt ggcgcagaaa aaaaggaaat
    19141 ttaccggatt atgaccgctc attaggaaaa aatcaacaaa ttatctgatt tttagagcgt
    19201 taaaaatgaa aaaaatttca ggagtggtaa aatgaattat agagtagcgg ttttaggacc
    19261 aggctcttgg ggtactgctt tggcacaagt cctcgccgaa aacggacatg acgttcggat
    19321 ttggggacat cgtgcttcac aagtagaaga aatcaacacc caacacacga atcaacgtta
    19381 tttaccagat cattatctac ccgattccat ccaagcattc accaatatgg aagatgcagt
    19441 aaaagacgca gatgcggtgc tattcgtcat tccaacgaaa gcaatacgtt ctgttgcaaa
    19501 agaactagtg cctaaattga atacaaagcc agtgatcatc catgcaagta aaggattaga
    19561 acagggaaca cataaaagga tctctgacat cttgttagag gaaatcccag cagaaaaaag
    19621 aaaagctgtt gttgttcttt ctggaccaag ccatgcagaa gaagtagcaa aacatgacat
    19681 cactacgatc acagctgcaa gtacagatgc aaaagcagca aaatatgtac aagagctgtt
    19741 catgaataat tattttcgga tctataccaa tcctgatgtg atcggtgtag agatgggggc
    19801 agctttgaaa aatattattg ctattggtgc tggcgctatt cacggcttag ggtttggcga
    19861 taatgcaaag gcagcaatca tgacgcgcgg attagctgag atcagccgtt taggtgtagc
    19921 aatgggtgcc aacccgctga cctttatcgg attaagcgga ataggcgatc tagtcgttac
    19981 ttgcacaagt gttcattcta ggaactggcg cgcaggcaac ttgttaggac aagggcagcc
    20041 cctagaagag gtgctagcca atatgggaat ggtcgttgaa ggtgtgaata ctacccaagc
    20101 agcgatggaa ctagcccaaa tgatggaaat cgaaatgccc atcactcaaa caatctatga
    20161 agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt tacgtgatgg
    20221 aaaaaaagaa aatgaattct cattaacaat tttttgaagg agcgaatgta tatgaaagtt
    20281 aaaaaagcag ttattccagc agcaggatta ggaacaagat ttttaccagc aacaaaagct
    20341 atggcaaagg aaatgttgcc aattgttgat aaaccaacaa tccagttcat cgttgaagaa
    20401 gcgttgaaat caggtatcga agacatcttg atcgttacag gaaaagctaa acgaccaatc
    20461 gaagatcact ttgattcaaa tattgaatta gaaacaaacc taagtgaaaa aggaaagacc
    20521 gaattattga aattagtaga agaaacgaca gatgtcaact tgcatttcat ccgtcaatct
    20581 catccaaagg gtttaggaca tgccgttctt caagcaagag cctttattgg aaatgaacca
    20641 tttgtcgtta tgctaggcga tgatataatg gaagacgaag taccattgac acagcaattg
    20701 atcgatgact atgagcgtac acacgcttct acgattgccg ttatgcaagt tcctcacgat
    20761 gaaacttcaa aatacggaat catcaaccca ggggaagtac tggaagatgg gttatacaat
    20821 gtcaaaaact ttgttgaaaa accagatcca agcaaagcac caagtgattt agctattatt
    20881 gggcgttact tattgactcc agaaatcttt gatgtattat cagaacaaca accaggtgct
    20941 ggaaatgaga tccaactaac tgacgcaatc gatacgttga ataaaacaca acgcgtattt
    21001 gcccgtaaat tcacaggtaa acgttatgac gttggtgaca aatttggttt tatgaaaaca
    21061 agtattgaat atggtctgac acatccagaa gtaggggcac ctttgcgtga atacatcatg
    21121 tctttaggta aaacattaga agcagaagga agcaagatca atcataatcc aaaaggaata
    21181 acagaaatca aagaagaaaa gaaaaaataa tctttttttc taacgagctt cagctgctaa
    21241 ttgaataaaa agtagttgaa gctcgttttt atttgtttaa aaaacacgaa aatgctatcc
    21301 ttatagaaaa gagagacaag aagggagttt gatcatgtca ggaggagaaa ttgcaggatt
    21361 gatcgcagca atcgcctttg cgatacttgt cgttttcatc gttcgcgtat tgttgcaagt
    21421 ttccaaaact ttagaaaaag tagaccagac tgtcgcagaa gcaaatacga caattgagat
    21481 cgtcacacaa gacgtagatc ttttatctag acaagtagaa ggcttgctag tcaaaagtaa
    21541 tgagctgctc ttggatatca atggaaaagt cgcaacgatc gatccattgt tcacagcagt
    21601 tgctgattta agtgaaagtg tatcggaact taatcattct agtaaaaaca tcgtgacgaa
    21661 agtcggcgga atcggaaaaa cgacagctaa agcgactgtt gccggaaaag tcggtggaac
    21721 agcgatgaaa ttttttaaaa acaaaaaaca tactgaaacg acaggaggaa aataagaatg
    21781 gctaaaaaag gtggattttt attaggtgca gtagttggag gtacagccgc agcaatcgcc
    21841 gcattattgt tagcacccaa atctggtaaa gaacttcggg atgaattggc tgctcaagca
    21901 gatgatttga tggacatggc ttcagattac acagatatgg caaaagaaaa atcatctgag
    21961 ttaacaggta ttgcaaaaga aaaagcgcaa ggtctttctc aacaagcagg ggatctagca
    22021 ggcaatgtta agcagaaggt aagtgaatca gcagaggaag caggaagtga atcagatgat
    22081 atcttgttaa acctcaaaga acaatcagct gatttatcta atcgtttcaa aaaaacagca
    22141 gaagatctga aaaagccagc agacgaatta ggtagtattg ctaaagatac ttcagaagat
    22201 atcatgatcg atgtaaaaga tgctgcagat aaagcaggag agacggtcaa tgaaggaatg
    22261 tcagaagcaa aaccagttgc agatgacaca aaagaaatgt tgaaaatggc aaaagaagat
    22321 gcaaaagaag ctaaaaaaga aatgaaagat acaatgacag attcgactac caatcactaa
    22381 gattactcat ttctagaata aaaaaggtga gagcggacca gctctcacct tttttatttt
    22441 cattactcta aaacaagtaa ttcttttggt gtagtcgtga atggcacaca accatcactt
    22501 gtcacataca cacaatcttc gatacgtacc cctacttttt caggaatata gattcctggt
    22561 tcaagagaga agcacatccc ttcttcaatc actaagtcgt ttccttctac aagagaaggg
    22621 aattcgtgga cggttgttcc gattccgtga cctaaacggt gattgaaata ttcgccgtag
    22681 ccatagctgt tgatcacgtt tcgtgcgatt tgatcaagtt cacctgctgt cacacctggg
    22741 cgaactgcct cttgtgcggc aagctgtgct tcaagagtga tgttatagat tttttcttgg
    22801 aactcagttg gtttttgata agcaactgta cgagtagcat cactgcaata gccattccaa
    22861 ataacgccaa gatcgaataa cactagttca tttggtgaaa ccttcgtgct tcctggtgta
    22921 ccatgagggc ttgcagcatt tgctcctgca aggactaatg tgtcgaaaga catttgtgaa
    22981 acaccttgtt tttttaattg gtattcgatt tctgcgataa ttgcttgttc agttacgcct
    23041 tcttttactg ttttgaagcc aatttcaaag gcaacatcgg cccatttacc agcttcgatc
    23101 agtttgtctt tttcttctac cgttttgatc agttgcagac gctggataat agaagttaga
    23161 tcggtgtaag aatctgtacc tgtcaagata tcagagatag catcgaagcg atcgacagtc
    23221 agagcattct tttcaatacc tacattacca ggttgcccat agcgtgcgcg aagctctttt
    23281 ccgatgatct cccaaggatt ttcgctgtct aagtagccac gtacatcgta cgcccagctg
    23341 ctgttttgag catcttcaac ttccagagca ggagtgaaaa ggaaaggatc ttgttccaga
    23401 gggataaaaa gagctagtac acgctcgtga ggatcacttt catatccgga aaagtaagcg
    23461 atgtggccag ggtcgctgat ataagccaat tctacttggt gttgtgccat ccattgacgt
    23521 agttcattga tttttacgtt attcatttgg caacctactt tctaaattaa ttttgtattc
    23581 aataattgta ccactgattg attaaaagac caacgttctt aaaactgaaa aaagtaaaaa
    23641 ttttcatgaa aacagagata aaacggttgc aattgttgag attatttgat atcctatttt
    23701 agaaatgtaa gacgtatttt cagaaaacat ataaaatatg aataggagaa cacaaatgga
    23761 aaagcaaaca atcactatct atgatgtagc gagagaggca aatgtttcga tggctactgt
    23821 ttcacgtgtc gtaaatggca atccaaacgt caaaccagca acaagaaaaa aagtcttgga
    23881 agttatcgat cgcttggatt atcgtccaaa tgcagtcgca cgtggcttgg caagtaagaa
    23941 aacaacaaca gttggggtaa tcattcctga tgtcagcaat atgttctttg cctctttagc
    24001 acgtggtatc gacgatgtgg caacaatgta caaatacaat atcatcttag caaactcaga
    24061 tggcaacgat caaaaagaag tcaatgtatt gaataattta ttggctaagc aagtggacgg
    24121 cgtgatcttt atgggtcacc atatcacaga cgaaatccgt ggagaatttt cacgttcaaa
    24181 aacgcctgtt gtactagctg gttccattga tccagatgaa caagtaggta gcgtaaacat
    24241 tgattatgtg tcagcaacaa aagatgcagt aaataaatta gcaaaaagcg gcaataaaaa
    24301 aatcgctttt gtcagcggtg cgctgattga tcctatcaat ggtcaaaacc gtctaaaagg
    24361 ctataaagaa gcattaagcg aaaacaatct accatatagc gaaggattga tttttgaggc
    24421 acaatacaac tttaaagatg gtctgtctct agttgaccgg atccataata gcggtgcaac
    24481 agctgtctat gtttcagacg atgaattagc cattggtatc ttggatggtt tattagaccg
    24541 cggcgtaaaa gtaccagaag aattcgaaat catcacaagc aacaattctt tactgacaga
    24601 agtagctcgt cctcgtttga caagtatcac acaaccatta tacgatttag gagcggtatc
    24661 catgcgccta ttgacgaaaa tgatgaataa agaagaagtc gaagaaaaaa cgattatctt
    24721 gccttatgga atcgaagaaa aaggatcaac taaataataa aagatcaatc atttaaaggt
    24781 tgttccaaaa gtggtcaact tctggaacaa cgtttatacg agaaaggggg ttatgacaaa
    24841 attttgtcat aacccctttt tttttgtgac tttaaaaaaa gagaaaatgg cggaaacaaa
    24901 ccttacgtcc atcgtatacg acacaatctg tgcgtagatg ctacattttg ttcactacta
    24961 tcaaaattac tttaaaatga aaacgtgata aaaaagaaag tagaaaagta gataagtaac
    25021 tctaaaaaat ccaaaaaaat ccaggctcga ttgcgtactt atcttaaagg agaaacaatc
    25081 catcatatat aacccgaaag gagacttcta tttgcctaag aaaagacgaa agaccatagt
    25141 catcattttg accattctta ctataggaat cggagggaaa ttttacatgg acaaaagaga
    25201 aatgcaaaga cagaaagatt tactcgcagt agaaaaacag tccgtcaaag ttctgaaaaa
    25261 tacctttgcg gatatcaagg aagtgaagat tgaaaaatct gctcgaaatg aaatgacggg
    25321 ttcataccgg atagttattc taatgactaa taaacaagat caatcgattt atttttctta
    25381 tagtttttgg aaagaaagaa atgagatagg aagttacgga atagttgatg aaaaaaagca
    25441 aaaagaagga aatacgctca ataaagttaa agtaacttac tctaatggaa atgaggaaag
    25501 tatttaatga ttactgacaa acaatatagt gaattaagtg atgctgttta ctggctagat
    25561 cctaaacata gagactatgt acctgaaatg caagaaaatt taagttttaa aattaacggc
    25621 actatgtata aaatcctaaa aatcaaaaac tccttcgacg gcatgcaggc gatggctgta
    25681 gcgccaatcg tccatagcaa attggagaaa aatttcaaaa ataaaaaaat tcctgcaaac
    25741 tttcgcgtac ttaaataatg aaggtgtcaa tacttacata aaaagaaagg aggcacgttc
    25801 ttgtcaagga aaataagaaa actcagctta gccattttat taatcgtcat attagggatc
    25861 ggagggaaag tctatatgga caaaagagaa gcacaaaggc agaaagattt actcgcagta
    25921 gaaaaacagt cagtcaaagt tctgaaaaat acctttgcgg atatcaggga agtgaaggta
    25981 gaagaattta aaaaaaaccc tgttaccgga agttatggtg cacttgtgac aatgacaaat
    26041 aatgaaggga aatctgttta ttttgattat agtttttgga aggagagaaa tgaacttggt
    26101 ggttttggca ttgagaacag agcggtacaa aagacaggag tcactataaa aagagtaaaa
    26161 gtaatttttt ctaacggaca ggaggagtta gtatgacaat aaacgataag cattacaatg
    26221 atattagtga gaaggtttat tggctagatc ccaaatatcc ccgctacaat gagggataca
    26281 aaaagaactc tgttaaagaa tttgctggta tggaatttca aatcctacaa atcaaagact
    26341 cattggacgg catgcaggcg atgtctgtag cgccaatcaa gaacggtaaa gtggatcttt
    26401 ctcaagtagt gattgctttt gcaggaacga acttaagtga ttggaaagat ttggaaacgg
    26461 atgcaagaag tatcatgaat ctctacggga atagaccagg agcaagtttt tctgaaaaag
    26521 caacaacaaa caagatttta tccgttagtg gattgaaaac agcggggcaa atcaattcag
    26581 cgattgcatt tgctaatgaa gtaaaaaagg aatatggaga agctgctatt tctactaccg
    26641 gccattcatt aggtggattc ttagcattat atgtagcagc agagaaacaa tggaaaaatg
    26701 tcggcttcaa cgggccggac ccgtatgatc tcttatcacc agaagcaaaa aaatgggtgg
    26761 aagaaaatcc cggtatgctc accaattacc gaaatcacgc cgattttatc ggtaattttg
    26821 gtggtaatgg cacaggtgct gaagttcgga tcagtatgga aacagcattc ttgaatctgc
    26881 ttgcttccca cagtttaacc tcttggaagt ttgatgaaaa tggaaagctg attattcctg
    26941 aaaatgaaaa caatgttaaa gctcgaaaac aacagaaaga aaaccaagcg acccagttgt
    27001 tttcctatca gttgcaagaa ctgaacaaca tacgtaaaaa actacgatta agtggcggcc
    27061 ggctgacagt taatgaacaa atttacttag atgacacaca agctaggtta gtagtggaaa
    27121 agttatcggc aaaaatgaaa agcgctatgg aagaagttat ccgcatcaat caaagaggaa
    27181 tttttgagct agagaaaaaa tggcaagaag gcttgcggca agcacgtgtt gtagcccctt
    27241 cgttgactga acaggaaatc atagaagcat tagctagtgt gggcgccaca aaagaaaact
    27301 tagtcgattc tgcgaaagaa gtctatctgc tacgaatcaa taaggcaaga cgtatggggg
    27361 aggcctttga tacattggcg aaggagatcc aagacaaaat caatgaaatc gtggcacgag
    27421 atcgagaatt agcacagcaa ttcaattaaa ggagaagtag atgaaactag aagaattgga
    27481 aagagattat cgaagtgaac gaagacaatt agaagctcaa gaagatgaat tgatccactt
    27541 taagaatcaa ggattacgat tgatggagca agaggagcag cgactgcatc atgtattaaa
    27601 gaacttagct ttagataatg agcctctgtt tcaagcaaga cgaagttatt cgaattatca
    27661 ggagcattat caacaagccc tacaagtaga acgacgaaaa ctctatcagc agcaagatga
    27721 actagaacgt tcctatcgtc aaaaaatcag acaaataact atggagaaat catcttatga
    27781 atgaattttt aatgcaatta ctaaaagaat tagagaaaaa tctacatcga tcaaatgtac
    27841 gttcagttgg tatggggata tctcagcaaa tttgggcaga aaaacgattg acagatcaaa
    27901 actaccaaat gactgcagaa gaagctgctc aagaattttc taaccgacat gtacacttga
    27961 aaggatcagt aaaagggcaa tttgcagaaa aactaactga attattccaa agacaagaaa
    28021 agaaattaaa acagtttcgt tagtaaagtt atatagaaaa attttgtgaa aatggtt
//
LOCUS       DAPBBR010000035        27555 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPBBR010000035 DAPBBR010000000
VERSION     DAPBBR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.035"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(116..1246)
                     /locus_tag="RD488_001703"
     CDS             complement(116..1246)
                     /locus_tag="RD488_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7657780.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1787..1993)
                     /locus_tag="RD488_001704"
     CDS             complement(1787..1993)
                     /locus_tag="RD488_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657781.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2009..2623)
                     /locus_tag="RD488_001705"
     CDS             complement(2009..2623)
                     /locus_tag="RD488_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDT7657782.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2770..3453)
                     /locus_tag="RD488_001706"
     CDS             complement(2770..3453)
                     /locus_tag="RD488_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7657783.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3562..4020)
                     /locus_tag="RD488_001707"
     CDS             complement(3562..4020)
                     /locus_tag="RD488_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDT7657784.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4104..5867)
                     /locus_tag="RD488_001708"
     CDS             complement(4104..5867)
                     /locus_tag="RD488_001708"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDT7657785.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6088..7548)
                     /locus_tag="RD488_001709"
     CDS             complement(6088..7548)
                     /locus_tag="RD488_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657786.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKED
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7756..8682)
                     /gene="glsA"
                     /locus_tag="RD488_001710"
     CDS             complement(7756..8682)
                     /gene="glsA"
                     /locus_tag="RD488_001710"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDT7657787.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8705..10132)
                     /locus_tag="RD488_001711"
     CDS             complement(8705..10132)
                     /locus_tag="RD488_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7657788.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10163..11377)
                     /locus_tag="RD488_001712"
     CDS             complement(10163..11377)
                     /locus_tag="RD488_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDT7657789.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11718..11960)
                     /locus_tag="RD488_001713"
     CDS             complement(11718..11960)
                     /locus_tag="RD488_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7657790.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(11992..12549)
                     /locus_tag="RD488_001714"
     CDS             complement(11992..12549)
                     /locus_tag="RD488_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7657791.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12562..12750)
                     /locus_tag="RD488_001715"
     CDS             complement(12562..12750)
                     /locus_tag="RD488_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7657792.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12763..13329)
                     /gene="amaP"
                     /locus_tag="RD488_001716"
     CDS             complement(12763..13329)
                     /gene="amaP"
                     /locus_tag="RD488_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7657793.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            13746..13919
                     /locus_tag="RD488_001717"
     CDS             13746..13919
                     /locus_tag="RD488_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657794.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            14559..15032
                     /locus_tag="RD488_001718"
     CDS             14559..15032
                     /locus_tag="RD488_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDT7657795.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            15041..15268
                     /locus_tag="RD488_001719"
     CDS             15041..15268
                     /locus_tag="RD488_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657796.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            15904..16275
                     /locus_tag="RD488_001720"
     CDS             15904..16275
                     /locus_tag="RD488_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657797.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(16531..16773)
                     /locus_tag="RD488_001721"
     CDS             complement(16531..16773)
                     /locus_tag="RD488_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7657798.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(16805..17707)
                     /locus_tag="RD488_001722"
     CDS             complement(16805..17707)
                     /locus_tag="RD488_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7657799.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(17720..17908)
                     /locus_tag="RD488_001723"
     CDS             complement(17720..17908)
                     /locus_tag="RD488_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7657800.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(17922..18485)
                     /gene="amaP"
                     /locus_tag="RD488_001724"
     CDS             complement(17922..18485)
                     /gene="amaP"
                     /locus_tag="RD488_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7657801.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(18523..19416)
                     /locus_tag="RD488_001725"
     CDS             complement(18523..19416)
                     /locus_tag="RD488_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7657802.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(19494..20417)
                     /locus_tag="RD488_001726"
     CDS             complement(19494..20417)
                     /locus_tag="RD488_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7657803.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(20466..20816)
                     /locus_tag="RD488_001727"
     CDS             complement(20466..20816)
                     /locus_tag="RD488_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7657804.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(20849..21751)
                     /locus_tag="RD488_001728"
     CDS             complement(20849..21751)
                     /locus_tag="RD488_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7657805.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(21744..22601)
                     /locus_tag="RD488_001729"
     CDS             complement(21744..22601)
                     /locus_tag="RD488_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7657806.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            22935..23744
                     /locus_tag="RD488_001730"
     CDS             22935..23744
                     /locus_tag="RD488_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7657807.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            23784..24281
                     /locus_tag="RD488_001731"
     CDS             23784..24281
                     /locus_tag="RD488_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7657808.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(24666..24739)
                     /locus_tag="RD488_001732"
     tRNA            complement(24666..24739)
                     /locus_tag="RD488_001732"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24703..24705),aa:Ile,seq:cat)
     gene            24926..25249
                     /locus_tag="RD488_001733"
     CDS             24926..25249
                     /locus_tag="RD488_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657809.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            25413..25667
                     /locus_tag="RD488_001734"
     CDS             25413..25667
                     /locus_tag="RD488_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657810.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            25737..25982
                     /locus_tag="RD488_001735"
     CDS             25737..25982
                     /locus_tag="RD488_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657811.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            26058..26423
                     /locus_tag="RD488_001736"
     CDS             26058..26423
                     /locus_tag="RD488_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657812.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(26484..27047)
                     /locus_tag="RD488_001737"
     CDS             complement(26484..27047)
                     /locus_tag="RD488_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657813.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         8161 a         5387 c         4525 g         9482 t
ORIGIN      
        1 tatgattttt tgagatactt tcattgcgaa ttcctctttc taaaagaacc tctcgcttga
       61 aaaataaaag attgtacttt atgataattc aaactgagag tttctcagtt tctctttatt
      121 gtttttcagg tcgatagagc gccaactctt cggcctgtat ctttgaagaa atattcaacg
      181 tgattccgat tcctaaagaa aggatcagat aacttgttcc tccgtagcta acaaatggca
      241 atggcacacc agtcattggc atcagccccg cgatacttcc cacgttcatt atcgtctgaa
      301 cgaatagcaa agttccgaat cctaaaagaa acaatccagc ttgctgattt ttacagcgac
      361 tgcttaaaca aaagattctc atgcataatg agaacaataa gaaaagcaca cacaatgcac
      421 cgattagccc aagctcttct gtaataatcg aaaaaataaa atctgtttct gtctctggaa
      481 gatacccttt ttttgtgata ctatttccta atccccgccc aaatatgcca ccattatata
      541 gtgcataaaa cgaatgggtc atttgatagc ccgcaccatg actatcgata aaagaatctc
      601 ttaaagtcgc gatcctttca taagcatgat taaacatctg tggaagccaa cctttatttc
      661 ctaaatataa taccccgcct gctgctccaa tcagcaatgc agaaaaagta acgattagat
      721 agatcccttt tttaaatgga accgccgctg cccaaaatat gacccacgca atcgaaagga
      781 tcatcaatgc tccagcaatc tttggctgaa ataaaatcag aaaagttata cctactgtaa
      841 tcaggaatgg tttttttaga tcttttgggc tactatttcc gtcacgaaaa aaccagctta
      901 aataaaaaat caaaaaaaga tttgccagtt cagaaggctg gaattgaatg ccaaacagag
      961 agatccaacg ttgtgcgccg ttgacagtga caccgaatat ccctattctt actaatacta
     1021 aaaagaaaat cgataaggct aaaccgtatc ctgctatttt agggtgaagt aaatagtgta
     1081 gtttgactga acgagctaag aagatcacgc tccaactcaa aaatatgaaa attagttgac
     1141 gcaataatag actttttgta ttttcatcgg cttgcaataa acgataagaa ctggcactgt
     1201 atacttctaa aagaccgatc atggacaaag tcaaataagg acccaaaatc caccaatcga
     1261 tcttttttca ccgcatctcc tcctcacaca gcaatccact tgtcaggtga ggagcgagtt
     1321 tgtctcatca aataagtcag tcacaaaaat ataaagaaaa ggtcagaaac cttttcgaac
     1381 aagaattctg acctagcatc atctcatcgt ccgagtttta gcactataca acgtaaagaa
     1441 aacattctta gctattggaa aaagccttaa tccaacagtt tctgttttac ccattggcga
     1501 ctttcgacgt ttctgggcaa cagcctatgt ttgtatagga gcctcaccta acaaggttat
     1561 tactatattc tatttacgag ttcatgatag acttttccta atgattaggc aatggaattt
     1621 gaaatgaaat agtgaaattt aacaatcttt aatatttttt agaaaaaaat aacaaataag
     1681 ttgaaagaat cccgttgcaa attctttcag ttgcaccagg attctttgat aattttttag
     1741 ttttatgtgt ttttttatat gttttttcac ttttcggaat aaatatttat ttgttaaagt
     1801 aattaaacaa tccgctaatc gtttgatctg gcatttctat ttccttacca tctaaagtaa
     1861 cagtagtaac gacaaaatgg tcttgcaatg gcggaacttc taagtactgc ccttgcagaa
     1921 aatcattcac tgtttcatat tcttttttca tttcttttga atctgtcgat ggtttatagc
     1981 ttatttttaa cataactagt gctccttttt attcgggacg tgcaatcgtg aaaatttctc
     2041 ctattgctgc ataatcattt cctgccaaac ggcttacagc attcaatttt cttggatcga
     2101 tccttcctgt cttatcatca tagactgttt catttaaatg atatttctgt acttctagca
     2161 aaaataaatc agctgttact ttatttttat tccgtatctc gacatgttca tataaggatg
     2221 tttcaaaacg aacttttgct tctgtcaatg ctggtactga aatgattact gaatcagtta
     2281 aagtcaagtc agtcaggtac agttcgcttt cctcattagg cagattggct gctgttttat
     2341 ttacttcttc tacgttgtcc tcatcaagga tatggataac agcttctctt gtctcaagaa
     2401 tattctttgc tgtgtctttt actgcatctt gttttctctg gatcgccaag gataagatgg
     2461 gtcgattcga actgacgata ttgaagtaac tgaagggtgc gatattcact atatcttttg
     2521 ctgatttagt cgttactact gctactggtc tagggatgac tgaaccaatc agcaacttgt
     2581 aattttcacg ttctgtcaat tctgaaggac tccgttcaaa catggtttcg ccttctttct
     2641 ataaaattcg ttaaaaagca gatcttgaag acaaaatgaa aagtaatgct tttttcatct
     2701 tcttagaatc tgctttaaac tatctatcaa tttttctttt ttgtcaagaa tctgtgccgt
     2761 gcgtgttttt tagttatttg ctttacttgc ggcttcgaca tatcttttag tgatcaattg
     2821 cggacgggtg ataatagatc caactacgac tgaaaaagca cctaattcat atgctttctc
     2881 tacttgttca ggagagtcag tatgtccttc cataattact gggatatcga cttgttctat
     2941 gatttgattc aataaatcaa aatcaggtgt ctgcgtcttt cgtgaatatt ctgtatagcc
     3001 tgctaaagtc gtagacaaaa gatcaaaacc atcttcttgc gcttgaagcg cttcctcaaa
     3061 agtcgaaata tctgccatag ctaaccgacc gtgttcgtga atcatttgga caagttcagc
     3121 agttgttttt tctgtcggac gtttacgaga agttgcatcc agtgcaatga tttctgcttg
     3181 cgtctccaaa agttcttcca cttctttttc tgtcgcagta ataaacactt ctgacccatc
     3241 gtaatctctt ttgataatcc ctattaccgg taaatcaacg attcgcttga tttcattgat
     3301 atcttctgtc gtatttgctc gaataccaac tgctccgcct tcttttgcag ccaaagccat
     3361 tctccccata ataaaagaac tgtgtagcgg ctcgttttcc aaagcttgac aagaaacgac
     3421 gactccgcct ttgatttgtt ccagtgtatc cacaatatct cctccagtaa tgttatataa
     3481 aaatacagct tcatataaaa atgtaaccct tttctattca ggagacaata atgagctatt
     3541 tctttcagca gacctttctt actaaaagaa aattacttca aattcttcgt atacgaccag
     3601 cttctcttct gtaaattcta tgttcaacgc ttctttataa gcatgtttaa aaaactcagc
     3661 atggactttc cgccaataag ctaatgtccg atccccttct ccttctttcc aagcatgctc
     3721 tttcgtgact tcactaaaag gcaagatggt cacatttata tttttgatga tacaaactgg
     3781 ttcatttttt ccattcagga ccacgtctaa ttgaccaact tttggtaaag gctcattctc
     3841 ttgtttatac agatcgtaac cacttgatgt accagtcttt atctttttta caactagttc
     3901 gctcaactcg tctgccattt tttctgtatc cccaaatgaa aagaaaccta atttttctga
     3961 ttgataacta ggatattttt cttggaactt tttgacatat tcttctactt gctgatacat
     4021 aacatccacc cctttgcttt ttataatgaa aaaaccatcc agatactagt ataaacaatt
     4081 atctggatgg tgagcataat gaattattga atattcaaga cacgcagact atcttcaacg
     4141 atttgttttg gtgttaaatg ataacgttca taaagctgcc ctacaggaac gctatccgtg
     4201 aattctttct ctgcaccaaa atttaatacg ttcattgaag aatcaccata ataacgactg
     4261 atattttcgc caaatcctcc tgacaaacta ccatcttcta atgtgatgac taattcgtgt
     4321 gtttctttta atttatctaa tgtttctacg tcattttctg tgatcgttcc tggattgatc
     4381 aacgttgctt cgattccttt ttttctaaaa gcttttactg tttcttttcc taattcaaga
     4441 aaaccgccta aagctaaaat tgctactttt cctccattat ttactgtttg ataggctgga
     4501 atactataat catttgcgat agctgtacca tgttctacac catgtgtagg aattcggatt
     4561 gctacaggct gcgctgtttg ttcgaacgcc caatctagca tagagatcat atcctctttt
     4621 gttgctggag caagatattt gatgttcggg atacttgata agtaaggaat gtcaaatgtt
     4681 ccttggtgtg ttcggtcact agctgagatc gttccgccac cgactaaaat aatcactgga
     4741 ttctcgttga tcgctaaatc atgtgataat tgatcatatg cccgttgcaa gaaagtactt
     4801 gattggaaga cgactggacg tactccctga gaagccaaag cagaagcgaa agtgatagag
     4861 tgctgttcag cgatccccac gtcaaaataa tgatctggat gtttttcttg gaatgttttc
     4921 agtccaaagg cgcctggtat cgctgcattg actgcggcaa taggagctgt acttgtttgc
     4981 attttcttat ccaaataatc catgatgatc atattaaatg tttctccaga agttacttgc
     5041 tttgcctccc cggtggacag atcaaatggt acatgccaat gatatttcat tttattatcg
     5101 attgccggct gataaccgcg acctttttcc gtatggacgt gaagtacaat cggatgatca
     5161 atatctttta cttcttcaaa taaacggatc accgtttcca gatcgtttcc attatccacg
     5221 taacgataat caaatcccat tgctttaaat aggttattgc tgcttttacc gttggtttga
     5281 cgaagctcag ctaagttttt atataaactg ccatgattct catcaataga catctcatta
     5341 tcgtttacta atacgattag attggattgt aaaacaccac cattgttcaa tccttcaaaa
     5401 gctaagccac cacttaggga gccgtcaccg ataaatgcta ccacatttcc tgattctttc
     5461 ttcagatctc tcgctttagc taaacctgtt gctaagctga tagatgtaga tgtgtgcccc
     5521 actgtaaaat agtcatgttt actttcatgt tggttggaat atccgctcac ttcacggtaa
     5581 tgtccttttt caaaaccatt ttttcgacca gttaaaagct tatgaccata agactgatgg
     5641 gaaacatccc aaacgatttt atcctttggt gaatcaaata cataatgaaa cgcaatcgtt
     5701 aattctacta cacctagatt cggaccaacg tgcccaccta catcgctgtc cttttgcaag
     5761 attttttggc gcatctcttc tgccaactgt ttcatttcct caacagataa ttttttgaca
     5821 tctgcggggc tattgattgc atccaataca tgtaatactg tactcataat acattctctc
     5881 ctccgtacta tcttctttta atgaaaatag atttgttaca ctttatctat tctactactt
     5941 agagttgact ctaagtcaat agcattttaa aaaaatttca gagaaagctt gttatataag
     6001 tagatcttcg cacgaatcag gactcaaata aaaaccttct acagacaatt aaaaagcttt
     6061 gtagaaggtc tcctaattaa ggtctcatca agaaatatgt ttttttaata ggtgaagttc
     6121 ctgagcaata tgatacaaat ggatgtttgc accttttaat gagattggat agatctttgt
     6181 cttttcagtt tctaatccat tttgatagct agcagcatcg cacaaaacca ctcttttttt
     6241 cgcacataga cattcatcag gcaattcttc taatgaacga aataaaatag gatttatttc
     6301 agcgatgcct tcttccgcat acaaatgaaa ttgggttcga taaaaaaatt gtttgactga
     6361 actttctgaa acaacaaaaa tttctatttc ctgtctcccc gcttgttcac tgttgatcaa
     6421 agaaagactt ttgacgaatt ttcgaatgaa attttcattc catcttagtt ggatttgatt
     6481 tttctttttc cactcttcca atatttctac aatttttccg tacagaagtt gttctttttc
     6541 tgatagaaga tagatccttt ccggtaaaaa tacttgtcca tctgcccaca acgtacggac
     6601 aaattgtaaa aaggattgct tgaaaataaa attttctgca tcgtcgattt cagcgatact
     6661 aataatctgt aaaatcaatt cattcagtga taggtcattg agaacaaaat ttttataaac
     6721 aacttcgaaa tcttttctta acagctccat gttctcattg gtataatttc tactgttgaa
     6781 caaagaaaaa atataataga catcttcttc ttgtaagtct agaattcctt tttgctcttc
     6841 caatccttga cagactaatt gaaataacgg cttcgtttct gcgcttttct tatcatcttc
     6901 tttcagtcca aggggaaatg cctttcttcc gattgcgatc tctattcctc gtatgataaa
     6961 ggacttttca tcttccgaat atcttctttt aaaaaaatga gtctctacat aatcaatcaa
     7021 ctcgttacaa gcttcttcta catacggatt tttattttca tagccttccc aattgacata
     7081 acgtactaaa gctagcaaga tgttccgcga gtcaaattct gggataatga tttctttatt
     7141 tttcaaataa tcattttctt taaaaaaatc caatacgatt tttttgattg tatatacttt
     7201 gctcaaagaa ataaattcaa gatcagccag ttctgtactc gtgaatatac cattaaaata
     7261 ataacttaaa aactttaaaa aataagattg accgtacaga aactgtgtga gctcagaaag
     7321 agcaatacca tgtttgaata cgagtttata cttatgcttc tctcttactt gttcttttat
     7381 acaatattct agacactcgg ctagactttc tagatcgtga aggatcgttg gtgtagtcac
     7441 ccttagagaa atagctgttt gttcgatgtc tatttcttgg aattcaaata attgttcaca
     7501 cagatacact tttctaaata tatttcgctc gatgtaattt tccagcattc ctgatacacg
     7561 cctccagttt ttcttatgat tttatttaat catatctgta aatcgtattt ttgtttcctt
     7621 tttatttaga aaagcccttt caaaaaccaa taaaaaaaga aactgggaca aaagtcaaac
     7681 aagctcacaa tttcagcctc attgtaggta gctttgagcc gtttggactt ttaccccagc
     7741 ctctttcaag aatggttatt caaagatgtc agcgtctagt tctttgacta catctttcaa
     7801 caattggata ccagctgcgc tgttaccaaa tggatctagt gccgggctga agacacctat
     7861 gccgtaacga tttggcacag ctgccatcaa cccgccgcct acaccgcttt ttgcaggtac
     7921 accaacatgg acggaaaact ctcctgattc atcatacaaa ccagcagttg tcataattga
     7981 tttgacgatt gtagcacttt cttcagtaat gatttgtttg ccattccaag gagcaattcc
     8041 tttatttgcc agcacagcag ctaattttgc tatgcctgta gcggtgacat tgagggagca
     8101 ttgtctgaaa taagcatcga gtatctccgg tacgtctcct tcgatcattt gattaccttt
     8161 catatagtaa gcaagagagc gattgatatc acctgttctt gattcagaat gatagatttc
     8221 ttcattcaat gtgatattag gatcatcaca gatctctttc ataaatgaca agattcgctc
     8281 aaatttttca tctgcatctt taccggcaat caacgaggtt gttgcaatcg ctcctgcatt
     8341 aacaaaagga ttcattggat gtttgcgatg attgatttcc atattcatga tagaattgaa
     8401 ggcaaaaccg gttggttccg tgttgattgt ttgaaagact ttttctattc cgttgtcttt
     8461 gattgctaat aacaatacgg gaacttttga catgctttcg atggcaaagc gcacatcggc
     8521 gtctcctccc tcaatcagtt gttttgtatc caaatcataa atcgccatac ctaattgttt
     8581 gggatccact tcagctaatg ctggaatgta atccgccact tgtcctgttt gataatagtg
     8641 gaaatttttt ccaatcaatt gttctaattc ttttacttcc atttgaataa ccagctttca
     8701 ttttttattt ttctgcatgc tggaatttat gacggcatgc gtagatcgta aatggaataa
     8761 ctaagacgat aagataagaa acaatcagaa tcgtttcata aatcccatgc tgtccagctg
     8821 cgatactagc aggtggaaca aatgagatac aaaaagcaaa aagtgaagtc aaaagaccta
     8881 aacaagcaac gattactttt acaacttttc cgcctggaac ctgataggct ctttcaagac
     8941 tgtcatcttt aaaaaccagc ttcaaatagc ccgcgaaaaa cataaagtac aacatcaggt
     9001 agattacaac agtcaatgac atcgctgcaa gaaatgaaag attattcccc ccgccgctta
     9061 atgtaaagac ggctgcccag attgttgcaa cgatcccatt tgcgatcatc aaatgagcag
     9121 gaacaccgtg tgtgttttct tttgcaaaat attcaggaag taatccttct tctgctgcta
     9181 cgtgaagtgc ttttgaagga gaggttaccc aagaagcaat ttctccgatg acacctaaac
     9241 aaacaagaat cgcaagaatt ttcgcaatcc atgcaagatt tggatcaatg tgtcttaata
     9301 ggaattctaa cgattgaatc acccctgtat taagagacaa accatgttga ggtactgtag
     9361 tagcgacggt caatccgcca aaagtatcta aaatgattgc cagaataacc aatacaaaca
     9421 ttgctaatgg ataatccttt ttagggtttt ccatttcatt tgcatgactg gcagatgttt
     9481 ctacgcccat atatgctaaa ataaaggaaa caaaaacaac cagcgtaggc aatttcgaaa
     9541 aatcaggaat caatgttttc atagacagta tcgtttgtag tggagcgcct gaagcgacat
     9601 aatggatccc taagccaaac aagactaatg ctggcaacaa gataccagct acaaaaccga
     9661 tccgagcaat caatgaagtg tatttggttc cttttaactg tgagagtaaa atagcccaga
     9721 aaataatcaa taggattgcc aatttcagat atttattgtt ttgtatagca ccaatacccg
     9781 ttgcatagga taatgcacca gttaagaaat acagcatggt caagtagcca actgttatct
     9841 caaaccattg gaaaaagatt gcggcaaaac cgaatcgttt tcccaatgtg cgactgaccc
     9901 aagtatagac accgcctttt tcccatcctt tcaccgttgc catctctgct gcgcacaatg
     9961 ccacagggat aaaccatagc aaaccgccta ataacaagaa aaatactaag ctgaagcctg
    10021 aggtcgcgaa tgtgggatat tcatataatg aaacgaccat tgagatggtc atagccaaaa
    10081 agccaaagaa cgttaatttt tttgcaggaa ttttcgtttt gctttgttgc atgaatcttc
    10141 ctcttttcta tttgaatttg tttcaattga gtttgttgcc aaagaagaaa aagtccaatc
    10201 cttcttcttg ttcttctttt gtagtagtga tcgttgtaaa gtgcatcgcc gattttaaaa
    10261 tcactgttgt cagcacatag gcatacacgg cagtaatgat gacaccaatc acttgaatcc
    10321 ctaagaagta ccagctgctt ggattcgtta gtaaatggct gttagatgca aagatcccta
    10381 tcagaatcgt acctgtgaat ccgcccatgc catgaacacc ccacacatca agtgcatcat
    10441 cccattgttt ctttttacga aaatcaacag cagcatgaca gacgataccc gcaatgatcc
    10501 caatcagcat ggcacttttt gcttctacat aaccggcaca aggcgtaatg gctgccaatc
    10561 cagcaacgga tcctgttagt acgtcgacaa aatcaaagcc atttcctttt acttttgcaa
    10621 tgatcagcca agtaatcatc gcaaatgcaa gagcgatgaa tgttgaacca aatgcattga
    10681 ctgcttgttc atctgctcga agtgcaccac cggaattaaa accgaaccag ccaaaccaaa
    10741 gcagtcctgt accgatagca gctgccataa gactgctatg ctgacttctt tctcctaaag
    10801 gaatctttct ttgaccaagt gtgaggatac atgctaaaga gccgaatcca gctgtcgtgt
    10861 ggatgactgc tccaccagcg aaatctctaa atcccatctg atccaaaaat ccgccacccc
    10921 atatccagtg gcaaacaggg aaataaatca gcagattcca aaaaataaca agtataatat
    10981 agccttttaa attcaatctc cctgcaaaag ctcctgtcat caaaggaacg gtaatcacga
    11041 taaacatcag ttggtaaaga aagaacatta aaaatggaat cgttgcacca tgaaacatgt
    11101 tggggaagct tgtaacatgt ctcatcaaaa agaaatctgc cgggtttcca ataacaccgc
    11161 cgatatcccg tccaaaggcc aatccgaatc caccaaatac ccacataatc gttgttatcc
    11221 caacggagag aaaagattga gacatgatcg ttagtatatt attcttccgt gctaatccgc
    11281 cgtaaaaaaa agctagacca ggagtcatca ggcaaaccat tgctgtacat aaaatcatga
    11341 atgctgtatc tcctgtattg ataggtaatg tattcatttt tttcgcctcc tttctacgat
    11401 tacgagtata aaagaaggtg tagttgtttt tttcttctgt ttttttgaat taatacttgc
    11461 atttataaaa gacagacaat taataaaagc ttgatgtgtt gtgctctttt tcgtttttca
    11521 cacaaataaa gacaaaaaat aaacggtctt ctttttatag aaaaccgttt attttcgtct
    11581 ttttttattt ttaaagatat tttttcataa ggaataaaga atacttcata taaaatatat
    11641 aaaaaagaac cgcagcgagt gtcgctacgg ttctcaaatt tgttcttcat ttcaacataa
    11701 gtttttcttc aatttgctta taatttacgt gcaaagaatg aaacgactaa tactaaaatg
    11761 attgcaccga tcaatgatgg aatgatagcc attcctgcaa ttgttggtcc ccaagttcct
    11821 agtaaagctt gtccaattgc tgaacctact aaaccagcaa tgatgtttgc gatgatcccc
    11881 attgatgatc ctttattcgt gattgctcct gcaattgctc caatgatacc gccgacgatt
    11941 aatgcccaaa taaatcccat tttaaattcc tcctaactga cttcttactt cttattgtac
    12001 acgtggttcg ttattttctt tgactttttg tgcacctttg cctacagcag attttgcttt
    12061 atctgtttgg cgtgaagcaa attgtcctgt ggattttgct gcttctgtta ctttgtcttg
    12121 tactgtttct tgatcttttt ggtattcttc ttgtgttttg atgtctgcaa cattcacatt
    12181 cacttcgata acatctaaat gtgtcatatt gtttacttca gtactgatca attctttgat
    12241 ttggttgtaa atatcttcga tgtctttacc gtattctacg atcacatcta gatccacagc
    12301 tacttgtttc ttacctactt ctgtattgat acctgctgtt acgttatctg tgttgactaa
    12361 tttttcagcc atatttgaga aaaatccgcc atctaatgtc aatagaccat ctacatcttt
    12421 caatgcataa ccgatgattt tttggatgac tttgtcttca taagtcaatt caccattcat
    12481 catgcggttt tctccttttt catttgccaa aactgatcca tttgttgtat tcatgttttt
    12541 gttttccatc tttgtttcct cctatgattt aaaaaattga tcaactattc ctgactgttt
    12601 caaataaaaa ccgattcctg cgccaattgc tgtcatgatt atgatcaaca atgtcttgaa
    12661 aaatccaatc gttaaccata aaacagctag cagtagtcca agacccccaa agataatagg
    12721 gagcttgtat gctgaaaata gttctttcat tatttggccc tcctattcca ctcgagagtg
    12781 cttgtagtct cttgtatctt cttgttcttc ataaccgctg tatgtgactg ccactttgac
    12841 cgtttctttt gttccgagta ctttagttac ttcttcttcg atatcttgca tcaatacacc
    12901 tgttttccct actaatgaag aagttcgttt caagtctccg ttgacatgga tatggattcg
    12961 atttttcgtt gaacgtatcc gtactttagg tgaatgaatg aactcttctt cgtgtaaatg
    13021 ggaacgtacc aacccttcga tcgctttttt gtcgattgtt agtttgccat cttcccgttt
    13081 cataacgaaa gttcctcttg actttggata gaaaagaacg actagcaaga tgataatagc
    13141 aagaacggca aatactacag ctgcccagaa aatatattgt tgcatgtagt aattcgttaa
    13201 agtaaagaag cgaaatcgtt ccaattgttc aggcataata tacggcgcat tgatcaacgc
    13261 aatcgctaga aatactgaaa gtagcagtaa actcatgata acaccgatta tttttaaccc
    13321 cttattcatt ttccacctcc tataaactta tttttaccct gtaaataact ctaccgacaa
    13381 tcacagtata gatagcgaac agttagcata gcatcagtaa ataaagcgct accaaacatt
    13441 gctggatcat aacggcgttt tattgccagt ctgatactga aataacaatt gcttacttat
    13501 tctctattta cttttgattg ctggctatac ttaaaggata ttattcaaga ttaaaaattg
    13561 caaagattat gctcagttat tattacaaga ttctatttat ttattaaatt ttttcggaga
    13621 attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt atttttatat
    13681 tatcattttt cttattcact tctttggttt atactattct tataaataaa aacgaggtat
    13741 gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat ttgattgtat
    13801 caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact actacattat
    13861 gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga aaaaaataaa
    13921 catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt attcggcaat
    13981 ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat aaactaatcc
    14041 aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc catgcgtcaa
    14101 tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata agtggtgatt
    14161 acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac ttgaaaaaat
    14221 taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct gttaacttac
    14281 acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat aatcccaggc
    14341 atctaaacta gcattataga agagacacac atagaatcta aaataactgg ttttaaatgt
    14401 ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct atcatttttt
    14461 ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa taattattct
    14521 gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa acattgctat
    14581 taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta cttttttata
    14641 ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca ttatttgttt
    14701 ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta ttgaaactat
    14761 tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata ctaaaaaaaa
    14821 tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct aaatttatga
    14881 aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct gtcgtattca
    14941 ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa catgcgattt
    15001 tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta tcgttaattt
    15061 agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga aagtgggcat
    15121 tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc gtttttccac
    15181 tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga cctataaaaa
    15241 tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa ataaaaaata
    15301 atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat tcagattttt
    15361 tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca tacaaagggg
    15421 gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct gttacgttgt
    15481 agttggatct gcttttagta taatacttta ttcattccac cagactgata gcagtttgag
    15541 cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga agtgcttaaa
    15601 acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt aagctcccat
    15661 atatactgta aagccttcta tatattatgt catgttgctt tttaacattt actatgtagt
    15721 tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt aacattattt
    15781 tgataataat gattatttat ttaaaaatac attagataac atttgttacg acacgaaaaa
    15841 gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat taggaggaat
    15901 agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat tccattacca
    15961 acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc tgctcttacg
    16021 aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta ttggctaaaa
    16081 cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct ctttgagttt
    16141 ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat catctgggtt
    16201 ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa atttagggag
    16261 gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag gaaaaacttt
    16321 taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa gtcttgtcac
    16381 agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat atgcccaacc
    16441 aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga tgaagaacag
    16501 ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga atgatacgat
    16561 tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg caatacttgg
    16621 tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg ctacgacatt
    16681 tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg ctccgataat
    16741 tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat gttttacttc
    16801 cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg cttccagctg
    16861 ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc gctgcgtcag
    16921 ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt ttgatgtcca
    16981 ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact tctttgccga
    17041 ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc acaatgacat
    17101 ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc gttacattat
    17161 ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca gataataaac
    17221 cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct tcataattca
    17281 gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta tttgtatgat
    17341 cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct tgtgctttcg
    17401 catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt gcatcatgtt
    17461 gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt tctgcatcat
    17521 gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga tgtgcagata
    17581 ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt gtcgttgggt
    17641 ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt ttgttattgt
    17701 tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc gtttgtttca
    17761 gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag gtcttgaaaa
    17821 agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag atgataggga
    17881 gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac tcgtttgcgg
    17941 tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac tttcactggc
    18001 tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa tgttcctgtt
    18061 ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc gatcttgttt
    18121 ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg caagtgagaa
    18181 cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc atgtttcagt
    18241 agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat aattgtcaaa
    18301 atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt agtgatggaa
    18361 aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa tagtatcgca
    18421 aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt tacaccttta
    18481 ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt tgatcgcttc
    18541 tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg atgctaagaa
    18601 aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac tttgctgacc
    18661 aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg tccagattgg
    18721 accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg ctaaaccgat
    18781 cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt cgcttggatt
    18841 gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat gcggaacagc
    18901 ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt tgacttgctc
    18961 aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta gtaccatcgt
    19021 atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg cttgttcgtc
    19081 acgaagatca aaaggtagta agacaatctt acgtcctgca actttcacgt attttgctac
    19141 ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg ccccttctct
    19201 agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga ttagtacacg
    19261 gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag gaacaggaat
    19321 catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct ccgtatggta
    19381 caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc tagtttttaa
    19441 attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat tctttaattt
    19501 gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa agagccaaag
    19561 actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt attcattccc
    19621 caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc tagatatttc
    19681 atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat actctctaat
    19741 aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg gacatcatag
    19801 agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa ttgatccatt
    19861 gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc aagatctgcc
    19921 tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa agcgtcaatt
    19981 cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa taatgtatac
    20041 gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag ccgatccaca
    20101 aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac aaaagatatt
    20161 ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac taccaaagaa
    20221 aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc ttccggatat
    20281 tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg ctcaatctct
    20341 tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt ttctattaca
    20401 ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg actttctcga
    20461 aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac tgcgatttca
    20521 ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg tttaccgaaa
    20581 taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat tttagtcgca
    20641 tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt tgcaaaagca
    20701 cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat ttttgtattt
    20761 tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat ttccattcct
    20821 actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt tttggttgaa
    20881 cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc gtcatccctg
    20941 catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac ggtttcacat
    21001 gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca cgttcacctg
    21061 ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc caacgcggat
    21121 gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca tggaatcgta
    21181 atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt tcatctaacc
    21241 attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat ttagctgaaa
    21301 ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct acgattgaat
    21361 caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg tcgcaatcca
    21421 tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca atacgataat
    21481 aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct ttattgattt
    21541 tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt aaaagctgtt
    21601 tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta gacgggttgc
    21661 aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt gtgttacaac
    21721 ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt tagagtactg
    21781 tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt attccaaggt
    21841 ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt atactgacgt
    21901 tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg catgttccat
    21961 tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc ttggtcgtga
    22021 tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt aatttctttt
    22081 ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa gtcatcggaa
    22141 tcgattccta atctttccaa agctttcact tggcctggat cgataatagc gccgattgtt
    22201 tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa cacatctgaa
    22261 tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa agaaattctt
    22321 aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat atctttttcc
    22381 actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc ttccaatcct
    22441 tctttactat attctgatag accatcgtca atcacataaa attttatgcg tcttgtttta
    22501 ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata attttcgtct
    22561 gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac tcctttttct
    22621 aatctttttc taacctgttc tacatctaga atattcctca tttggtttta aagcaaaata
    22681 tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca tcggtaagcg
    22741 ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac tactatatat
    22801 agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag caagttagtt
    22861 tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat gtaaaaagaa
    22921 agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg cttgatcgaa
    22981 atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa aatggcggaa
    23041 tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt tccgaattag
    23101 gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg aaggatggaa
    23161 aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga aaagccttct
    23221 tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa gatgatcagc
    23281 tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat ttcaatttac
    23341 agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt agctatctta
    23401 aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga gatctgcaag
    23461 cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg cctacaggta
    23521 tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa tcgagtgaca
    23581 tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc gggttgagta
    23641 ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta acactgacga
    23701 atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa taaaatgacg
    23761 atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat catattcttg
    23821 atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt attgctcaaa
    23881 gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat ataccagttg
    23941 aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt ctttctccac
    24001 aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa actttagctg
    24061 aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa gtagtcggga
    24121 ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct tttcctgaag
    24181 cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa tccgctttag
    24241 agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta tcttcattta
    24301 cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac gtgctttttc
    24361 tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca cgacctcttt
    24421 cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc aaaatatgag
    24481 gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt cacaacctct
    24541 tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa gtaaaaacat
    24601 aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc
    24661 tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg tctgctctaa
    24721 ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt caactatagc
    24781 acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt tattcttatt
    24841 tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta ttttagaaaa
    24901 aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat ttattgcgat
    24961 tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc aaacctcagg
    25021 aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc ttgtcatgat
    25081 gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg ttaaatatgt
    25141 ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg tcctcttttt
    25201 atatgtattg aattacttag atatcaatcc attgattttt tctcgataga taagacacat
    25261 tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat ttttcattga
    25321 tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa catgttatct
    25381 tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga gttttgtttt
    25441 gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg aacaaagaac
    25501 ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa gtttttaatt
    25561 acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg gttttgtctt
    25621 tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta ctattgattg
    25681 catgtgtagc tttctatagt cattataact attctactat aatgaaaggt gattaaatga
    25741 gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc ttaagaactg
    25801 gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta ttcaaatatc
    25861 gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat atcgctgact
    25921 tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc aaactgaagt
    25981 gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa caatctatat
    26041 ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag cttcctcgtc
    26101 aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc tggggaaaga
    26161 aacatgctac tgtggattat gtttttcact attctcctta tagattattc caatatcatc
    26221 agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag tggaaaaatc
    26281 ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta gagcgcaacg
    26341 tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca aatttggagc
    26401 aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct cttacttcat
    26461 taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg gttatcttca
    26521 tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac ttccctagac
    26581 ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc tgtatacgat
    26641 gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct tcttctacac
    26701 cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc catgcatcgt
    26761 cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc tgtcgtggct
    26821 tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc tgccattgct
    26881 agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc ctgaaaatag
    26941 actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat ttctaaatat
    27001 tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt tatttttaaa
    27061 aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa aaaaattatt
    27121 acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct ttcatcactt
    27181 gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg tattccttca
    27241 aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact taaaaattta
    27301 gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat tgacagacca
    27361 atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt cattttcaag
    27421 acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta ttcgtatttt
    27481 cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta ttcagcccat
    27541 tcaacgacca atgaa
//
LOCUS       DAPBBR010000036        26574 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPBBR010000036 DAPBBR010000000
VERSION     DAPBBR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.036"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(324..893)
                     /locus_tag="RD488_001738"
     CDS             complement(324..893)
                     /locus_tag="RD488_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7657814.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="RD488_001739"
     CDS             complement(967..2256)
                     /locus_tag="RD488_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657815.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2610..3458
                     /locus_tag="RD488_001740"
     CDS             2610..3458
                     /locus_tag="RD488_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDT7657816.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPVPVR"
     gene            3472..4545
                     /locus_tag="RD488_001741"
     CDS             3472..4545
                     /locus_tag="RD488_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HDT7657817.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="RD488_001742"
     CDS             4535..6706
                     /locus_tag="RD488_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDT7657818.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8974)
                     /gene="copB"
                     /locus_tag="RD488_001743"
     CDS             complement(6818..8974)
                     /gene="copB"
                     /locus_tag="RD488_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HDT7657819.1"
                     /translation="MHMGHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHMGHNHG
                     DIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGMEFPFQ
                     VTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYIYSVYS
                     FIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPESVKRL
                     TKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGIKKQAN
                     DKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAKWLFYV
                     ALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAAKNGLL
                     LKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGALEANAN
                     HPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLGLNVEQ
                     ALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVMLTGDNK
                     NAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLARASIGM
                     AIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILAIPLAA
                     GILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9117..11303)
                     /locus_tag="RD488_001744"
     CDS             complement(9117..11303)
                     /locus_tag="RD488_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDT7657820.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11303..11512)
                     /gene="copZ"
                     /locus_tag="RD488_001745"
     CDS             complement(11303..11512)
                     /gene="copZ"
                     /locus_tag="RD488_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDT7657821.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11525..11965)
                     /locus_tag="RD488_001746"
     CDS             complement(11525..11965)
                     /locus_tag="RD488_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HDT7657822.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12039..12512)
                     /locus_tag="RD488_001747"
     CDS             complement(12039..12512)
                     /locus_tag="RD488_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HDT7657823.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFMVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            complement(12822..14288)
                     /locus_tag="RD488_001748"
     CDS             complement(12822..14288)
                     /locus_tag="RD488_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7657824.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(14599..16683)
                     /gene="cadA"
                     /locus_tag="RD488_001749"
     CDS             complement(14599..16683)
                     /gene="cadA"
                     /locus_tag="RD488_001749"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7657825.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            complement(17207..17566)
                     /locus_tag="RD488_001750"
     CDS             complement(17207..17566)
                     /locus_tag="RD488_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDT7657826.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(17596..17937)
                     /locus_tag="RD488_001751"
     CDS             complement(17596..17937)
                     /locus_tag="RD488_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657827.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(17934..18608)
                     /locus_tag="RD488_001752"
     CDS             complement(17934..18608)
                     /locus_tag="RD488_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7657828.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            complement(19403..20701)
                     /gene="asnS"
                     /locus_tag="RD488_001753"
     CDS             complement(19403..20701)
                     /gene="asnS"
                     /locus_tag="RD488_001753"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDT7657829.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(20741..21931)
                     /locus_tag="RD488_001754"
     CDS             complement(20741..21931)
                     /locus_tag="RD488_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7657830.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGKSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(21952..22479)
                     /locus_tag="RD488_001755"
     CDS             complement(21952..22479)
                     /locus_tag="RD488_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HDT7657831.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(22526..25315)
                     /locus_tag="RD488_001756"
     CDS             complement(22526..25315)
                     /locus_tag="RD488_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7657832.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(25462..25662)
                     /locus_tag="RD488_001757"
     CDS             complement(25462..25662)
                     /locus_tag="RD488_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7657833.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(26114..26434)
                     /locus_tag="RD488_001758"
     CDS             complement(26114..26434)
                     /locus_tag="RD488_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657834.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7469 a         5626 c         4666 g         8813 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgggaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgtcccatgt gcatggaatg gtccatctgg ctatggtcat
     9001 gtttcatctc catctgtttt tcatgagatt ctgtactttc tttgtttact acttcttttt
     9061 tatgttcatg ttttttctcc atatcgttcc cattcatttt tactccatcc cttctcttac
     9121 tttttcatgt gccgatttaa gctcagggag ttcaacaata cactgacgga actaaacgcc
     9181 atcgctcctc ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg aataccaatc
     9241 gtattataga caaaagccca gaaaagattt tgtttgattt ttctcaatgt caccctagac
     9301 aactcgattg tttgtgcaat ggatgccaaa ctgctactca tcagcgtcac atcggctgtt
     9361 tccatcgcga tatccgttcc acttcccatt gccataccaa catcagctaa tgctaaagcc
     9421 ggtgcatcat tgattccatc gcctgccata ccgacttttt tgccatcttt ctgaagtttt
     9481 tctacgtagg ctgctttatc ctctggaagt acttcagcaa agatatgctt tggatcaata
     9541 ccaacttgtt taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag cataaaaaca
     9601 tctaatcctt tattctggag ctgcttgatt gcttgtttgg cttctagttt gatttgatca
     9661 gccacggcaa tcaacccgat cacttgcttt tcatcagcta aaaacatgac tgtttttccc
     9721 tgctgttcta attctaacgc gtgttcttgg tattcatcaa atgataggtt caattcaatt
     9781 aatcgtttac gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct gattccagca
     9841 cctgggtgag ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag ttttccgtat
     9901 tccacgattg ctttacctag tggatgttca gaagcttgtt ctaaagtata aaaaatagat
     9961 aggacttctt tagaaccgac tagatctgta actttgggct ttccttctgt aatcgtccca
    10021 gttttatcca aaacaatgct gtctaagtga gcagctgctt ctaatgcttc tccgccttta
    10081 attaaaattc catttcgtgc accaacaccc gttcctacca taatagctgt tggagtcgct
    10141 aaacctaatg cacatggaca cgcaatgact aatacagaga cactatggat caatgcgagt
    10201 tgccaatcac cagtgatcaa acctgtagct atgagcgtga taaacgcgat gactaatacg
    10261 atcggaacaa aaatccctga gatccgatct gcgatttttt ggattggggc tttgctccct
    10321 tgagcatctt ccaccatttg aatgatttgc gctaatactg tctgcttgcc gacttgtgtg
    10381 acttccatgt gtagcagacc attcgtattg attgtcccgc caaaaagcgt gtcatccgga
    10441 ttcttttcta caggaagatt ttcaccagta agcatacttt catctatcgc actgcttcct
    10501 gaaataattc gaccatctgc tggaatctgc tcaccaggac ggatgactag ttgatcacca
    10561 acgactactt cttcaatcgc taacgtttct tctttcccgt ttcttatcac ttgggcggtt
    10621 tttgtttgaa gagacatcaa ttgtttgatt gcattacctg ttttcgtttt tgctgtatgt
    10681 tccaaatatt tgccgagcaa aatcagcgtg atgatcatac tgctgctttc aaaataaaga
    10741 tcttgggggt gtccacggaa aaatccgttg taaatgctca atgcaaaggc agccgatgtt
    10801 ccaattgcta ccaatacatc catatttggt gctttcgact tgattgcatg gtacgcacct
    10861 ttataaaaac gagcaccgac ataaaattgg acaggagcag acagcactaa ctggacgatt
    10921 ggaaaatgaa aaaagtgaac aatcgccgca tggcttccta acatcatagc aatcattgac
    10981 aacatcaacg gcaaagtcaa aaccgtactc aatataagat cgaatagcat ttttttcaaa
    11041 tacgcttgct tttcttctgc aattttttgt ttgtgggctt catcgtacaa aattgcacca
    11101 tagccgatgt tttctacgct ttggattaat ttttcagtgg tcgtcccttc atatttgaca
    11161 cttgcttttt cagtggccaa gttgactgtg gcattgacca caccaggttg tccgttcagc
    11221 tctttttcga tcctagcaga acaatttgca caagtcatac ctgtaatgac gaacgtatcc
    11281 attttggttt ctgctgttgc catcaaatca cctctgcttt ataacccaat ccattgattg
    11341 cttgacaaat cttttcggat tgaacttttg tttcatcaaa cttgaccgta ccgtttgctt
    11401 ttttcaaatt tactttcact ttttgcacgc cgtcaagtgc gcttactgtt tcttctactc
    11461 ttgctgcaca atgattgcag ctcatacctt cgattgaaaa ttgttgtttc attttttctt
    11521 cctcctattg atgttgttta cattcacatt gacctgggat acagttacat tcgatcgtat
    11581 ctactggttg cttttgttcc agttgtttca aaatctcatt gatatcttct tgagtcaaag
    11641 tggcttcttc tactagatcc gcaatcgtct ctccaatcct ttttgcacag atatgggaaa
    11701 aaagattttc cgtcgcactg cgaactgttt ccatctccga gacagctgga tgataaatga
    11761 atttttttcc ttcttgttct gtccagatca cttctttttt taccaaacga cccagcaaag
    11821 ttttgatcgt tgctggtttc caatccatcg aatcagctaa gatctgcgtg atttcttggg
    11881 ctgtcgtctg tccaagtgtc caaataacac gcatgatctc ccactctgaa tcactaatct
    11941 ttactggcgt tttgactttt tccatttatt tcacaccttt cgtttacaaa tgtaatcatt
    12001 aacttatgaa tacagattac acttgtaaac aaaaactgtc aattattttt gctctctatt
    12061 ttcaatttag ttaaaaattc ttgtttctct cgtcttgttt taaggatgat cagtttattt
    12121 cttgcattag ctacttggat cagctgctgt atttttggtt cattgtttcc ttcaaaatgc
    12181 cagataaaag ataaaaattc taagtatttc ctgtttagtt tctccgaaaa tgattcaggc
    12241 atatctggcc gagatttttt gtttatcttt ctttttagag aacgccaaac tactcggtag
    12301 atggcgagat aacgcggcac tttaagccaa atgatcttat ctgcttcttt aatcctttcc
    12361 tctaacgtag aagtataatt tccttcaacg atccatgacg gattagatac cataaacgat
    12421 tgctgttctt gcaaaaacca cttttttgcc tgaatgcgga aagccggtga tttctttgat
    12481 cttccttgcg agggacgatt ttcccgaccc actttgtcca atcacgatga tcttcattct
    12541 tctccctcac ttctctttgg aatttggttc gatcatacca cttataacgc cgcaaaaaaa
    12601 caagggactg tgacaaaagt cgtgtcaaag tcccttgttt cgaataaatg gtgttcaatc
    12661 agctgacctt cagcattagc tcaaaaaacg gcaaaatatg aggagctatt tttgtttggc
    12721 tgttcttatt acttgatgca ggacagcttt ttcacaacct ctgattcacg gtgttccaga
    12781 agtagcttct gtcacaacct cttgtaacaa gtatttctat tttaaggctg aaccactgtt
    12841 tctggttcag taatttcttt gtttttgtct cgacgagcaa ttgctggcaa gatcatacct
    12901 aataagatca agacaattgg tgtgatgata ttcgtgaata attggaacca ccatgcttta
    12961 ggatcagcag tataatctac ttttggcacc attcctagga tacatgcaaa cgcagtgaag
    13021 gcaaagcacc aagcaccaaa gataaaaccg atttttggat ttttaacaaa tttatattca
    13081 gaattgaatt tcttataagc tttattcaac atcatatatg ccaagaacac ccataggtaa
    13141 cgcattggca tgacaactga gttcaagttc gtcaaccatt ttactaattc attcatatct
    13201 ttgataccaa agatcggcaa caaaataatg attcctacta gtatacctgt cagaagataa
    13261 ccattcacca atgtaccttt acgattacgt ttacgtagcc agtttggtac aaattctgga
    13321 tccgcatctg ctaacaagat ttttagtggt gcatcaattg aaaaggctaa tgcggagatt
    13381 tgtccaatca tgtttgtcaa tgcgtaaatg atcatcaatg agttaccgat accatagtaa
    13441 ttacctaaaa tttgaaaagc actgtatgcc ccatttgcca tcaagtcttt agggatatta
    13501 tcgctagcaa acagcatacc cattgcgact gagcctaata cagcacaaat ccctaccatt
    13561 gctgctaaga agatcatccc tttaggaaat tcctttgcag gatttcttgt agagttgaca
    13621 taaggggata ttttttccgc ccctccaact gcaaatacta gcatcgaaac ggttgtgaaa
    13681 taactgaaat caaatgttgg aatatatgtt ttcacttgat tcatatgtgg tgtggcaaat
    13741 tccatcgttg gattgatgaa cggtgccgtt acagctaaaa gaataaataa gatcgacatg
    13801 acgaacatcg ctgttccggc cagtccgcca atcactttca aagtagaaag tccttttgtt
    13861 gataaatata aaaaggcaag aaatataata agtgaaataa ctgctaccat ttgtactgac
    13921 atcgtattta cgatatttcc atttccttgg actgcccaac caccagcaat cagaattgct
    13981 tgaggctttt gtgccaaata aggaatatgg acgacccagt aagtccaagc ggcatagtat
    14041 gccagtcgtt tattagatgt cgtattttcg acccatgaac tgacgcctcc tttactatcc
    14101 ttgaaggctg atcctaattg tccaacgatc aatgcgtatg gaataaaata aatggccaaa
    14161 atcaatagcc aagaggtgac aactgatact ccttgctgag catagttatt aactacattc
    14221 cccatgcccc aaaccatgtt aaatgcaatt aacgcaacag taaaccagcg taattgtttg
    14281 ttgttcattc gttctctcct ttatgataaa aatttgttat ccagatgtaa tcatattcaa
    14341 tttttaacaa acttacaaga cagtgttatt ttatgtgtgt attcttttat ttaatacaca
    14401 tcgttttttc atattttttc catcaaaaaa ataagttatt ttcttttatt tcattgacct
    14461 tattgaattt caagctattt tgaattttct gcaaaattaa aaacattagt tattttataa
    14521 tcctatctat tttctttaca tttttcatta agaaaaggat ataaaaaaaa gaggacgttc
    14581 attcgtcctc ttcattgatc aacgtttatt ttttacatgc aagcttcgca tggcattcaa
    14641 aacagctaat actgtcaccc caacatctgc aaatactgca tctcccattg atgcaaaacc
    14701 aaaagcacct aaggaaagta ccaaaatttt tatcccaata gcaaagacaa tgttctgttt
    14761 gacgattttc aatgttttct ttgctaaatg gattgcttct gcaatcttcg atggttgatc
    14821 attcatgatg actacatctg ctgcttcaat tgcagcatcg cttcccaatc cacccattgc
    14881 gattcctaca tctgctcttg ctagcaccgg tgcatcgttg attccatctc cgacaaatgc
    14941 ggtcttttta ttgttacttt gtaagatttc ctctaaccgc tgcactttat cttctggaag
    15001 caattcgcta tatatcttgt ccacgcctac ttgcttcccg atatgatcag caattttttt
    15061 cgagtcgccc gtcaacatga ctgtgttttt cacaccagcc tgttttaatt gaaccaatgc
    15121 gtctacggca tcttctttca aggtatctgc aataacaaga taaccactgt aactttgatc
    15181 gatcgctaga taaagcaatg taccgatttc ttgacttgaa ggaaaagaga tttcaaatct
    15241 ttccatcaat ttgtgattac ctactaatac ttgtttgcca tcaacttcag ctaagatccc
    15301 ttcacctgca aattcctgga tattagctgt tggtaaaagc ggacctgcgt agccttctaa
    15361 aacagattga gcaatcggat gtgtagaaaa ctgttctgca cttgcaacat attgcataaa
    15421 tttctttgga tcaattcctg ttggatcgat cgtctggatc gaaaagtcac ctttcgttaa
    15481 tgtgccagtt ttatcgaata ccactgtctc agtttgtgca agcaactcca agtaatttga
    15541 accttttact aatacaccga ttttacttgc tcctccgata ccgccaaaga aactaagtgg
    15601 cacggaaatc actaatgcac atggacatga gatcactaaa aatgtcaatg ctcgatagat
    15661 ccattcagaa aacgccgctc tagaaacaac aagtggaggt aaaacagcta ataaaacggc
    15721 caatcctaca acgactggtg tgtaatagcg cgcgaattta gtaatgaaat tttcagctgg
    15781 tgctttttta ctgctggcat tttctactaa ttctaataat ttgctgatag tagaattttc
    15841 ataagatttt tctacttgaa ctaaaaatgg tttattttta ttgataaatc cgcttaatac
    15901 tgtttcacca acatatacag atttagggac tgattctcct gtaagtgctg acgtatcgac
    15961 taatgattct ccttcgatga tcgttccatc taacggtaca cgttcaccag gcttcacaag
    16021 tacaaactga ccgatcagca cgtcttcagg gttcacggtc atcaatcctt ccgccgtctg
    16081 cacgtgagct gtttctggac ggatcgccat caattcgcga atcgattttc ttgaatgact
    16141 gactgccaat ccttggaaat actcgccgat ttgataaaat agcatcactg ctacggcttc
    16201 tggatattca ccgatcaaca tagcgccaat cgtagcaaca gacataagaa aattctcatc
    16261 aaagattttt cctttgacga tattcatcac tgccttcttc actacatcat atcctatcag
    16321 cagataaatc aataaatacc ctatcaagcg aattggttca ttaaaatcaa ataatagcaa
    16381 taaagcgata cctgcaaggg aaaataaaat ccggaacagc gtatttctct ttttttcatt
    16441 tccatgttca gatacttttt ccttatctat ttctgttact ttgacatctg gttctaattc
    16501 cttcactact ttttttgttt cttgttcaat cgtagccaaa tgatcttcct ctgcgtcaat
    16561 cgttagtttt ccagaagtga agtttaccgt tgcttccttg actccattga ttttctgaac
    16621 tcctttttcg attttcattg cacagttcgc acaatctaaa ccttctaatc tgtaactttt
    16681 cattttaatg acctcctcgc ctcaacatat gaatatctct tcataactaa ttataaatga
    16741 atggttattc atatgtcaag gtatccgaaa gaaaaaatga aaaacatctg catcggaaaa
    16801 tttcttccat acagatgttt tggcttattc tttctttttc tcttcgatca ttgccactgc
    16861 tcttatccaa cccgcacttg ccttcttgat cttgacagga tagcaactaa gtttgaagcc
    16921 tgttgctggc aatttgtcta aattcattaa tttttcgata ggacaatatc ttttttcaat
    16981 ccctgcaaaa tgtccttccc agatatacga agctccacta cgctttcaaa aatatagaaa
    17041 gagttcttta atgaaaatta tttcaacttt ccataaacag taaccccata taaataaaag
    17101 acgtaaaagt cacatagaag aacttataca ggaaaacgca tagagtcagg tgaaatacat
    17161 gtatcccacc tggctctatg ctttatctaa cctttattat tctcttttat acaatttctg
    17221 caccgaatgg catcaacgcc aatcgagcaa gtttgaaaga ttgcttggca aaaggtatcc
    17281 ctatgatcgt gatacataga aggatgccgc tgacgacatg tgcgagagca attggtaggc
    17341 ctgaaacgat cagccagatg atattaacga tcaatgacat gccagactgg tgataaatta
    17401 cttctttgcc aaaaggcgca aaagaaaggg aggcgatctt aaaacattgc ataccgattg
    17461 ggatacctat gatcgtgata caccaaagta tccccgctgc taaccagcta agaccaccga
    17521 ttagtccgcc gaatataaac cagatgacat ttcctaaaca actcattgta tttctccttc
    17581 tattactgtt tttgattaaa actgggcaaa aattgatttt attcttcttt ttttagcttc
    17641 cagcatcaag tattctgcaa attttttttg gatttcttcc gtattttctt ttgttactaa
    17701 tgtgtgttgg attagttttc ctgatggtcg ctgatccaat cgttcttctg actgttgcac
    17761 gtccgcttgc gcaaatccga taatccgttt ttcttttgtt acagcaacga gcaatagttt
    17821 attcttatca tttaggtcag ctgccgtttt tgcttttacg aatgattctg gatgatcagt
    17881 aatcagctga ttgatttgag gtaaatcttc ttttactgcc caccttattt ccatcatttt
    17941 tcacttttct ttcgctcatt tttatctcca ctaaaaaaat cgactgcgac aattgcatct
    18001 atccagcttt gtgcaatgat ctcatgtccg ccaatcgttg ggtggacccc atcttctctt
    18061 gtatatttcg aaaaaccata agcaatccct aaagcattga atataccatc taaaggaacc
    18121 agcaatgcgc catattcctt agcaagttta cgaacaattt ggattttagg gtctaagtct
    18181 ttacgccagc catgacggtc gtcggttata ggaagtacaa acggctccat caagatgatg
    18241 ttgcagattt ccgctgtttg aagttcattt agtaattttc gataaacgga ttcaaattgc
    18301 tgagcagatt tctcagttcc gaatatagcc tgatcgctag tattatgcca ggtatcattg
    18361 attccgatca aaatcgatac atagtcaggt tgtaaagcta aacaatcttc ttgccagcgt
    18421 acttgcagat ctgcaatttt gtctcctcct atcccacggt tcatgcattc aaattccatc
    18481 gttggatatt gggagattag ttttccggca atcaaaagtg gataaccttt acctagatca
    18541 gttgcttctg ctcggtatct tcctgcgtct gtaatgctat caccgataaa taatatacgt
    18601 tttttcattt gtcaaaaact cctttttgaa taaaacgatg attttcttcc ttatattatc
    18661 ccataagccc tatcaagacg aaagagaaaa tatatgtata aaaaatgaca ccagcctagt
    18721 tccttcaaac aattgaatga acgctcatca agtgtctagt tttttatgct atttttttct
    18781 taacgtgccg gattcccctt gattccttcg ttgtttggtc cagagagatc gatcacaccc
    18841 aagcttccgt caatcagacc actgatgacg ccatcgaaac atatatttat aggctcatct
    18901 aagacttcta gtaaatgtcc ctttactaat atctcttcta gattgcttgg gatagattgg
    18961 tcataacttt atctggtccg atgatttcaa gggtgaattg aacttacata tggattattg
    19021 catgctgaaa atacggacct actccatctt cgaatgttac tattagtttg ttttcaggtg
    19081 ctagatgctg ctttatttca acagcagaag catcatcaaa tcagatttcc atttgaatta
    19141 ccttctttgt aaatgtttga ttgattgcga tttcgttata gaaccttgtg aatcaaatag
    19201 caatttcttt tgctttcttc tcttgtctgc tggaaacttc cattatcccg tatttaaaaa
    19261 aaagaactgc gagagttcgc agttcttttt tttaaataaa cgttgctctc cggccacaag
    19321 tcacaatagt catcaaacat gaaaaactgt tttttgaaat tactccttgt gactcggagc
    19381 tgaacggcag gcgcacaacc tcttatggat aaattcggtt caacaaacgt gggaatggaa
    19441 tagcttcacg tacatggtcg ataccagcaa tccaagtgac tgttcgttca agacctagac
    19501 caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc aagataccat gaatattctt
    19561 tttcatccaa accgtgatta cggatttgtt ctagcaagaa atcatagtcc gttgcccgtt
    19621 cgcttccgcc aataatttca ccgtaacctt ctggtgcgat catatctgca caaattacca
    19681 cgtcttctct tgttggatgt ggtttcatgt agaatggctt gatggctttt ggatagttta
    19741 ggataaagac aggctgttcg aatgaattcg caatgaacgt ttcatgaggt gaaccaaagt
    19801 cttcgcccca ttcgatgtca tcaaatccat ttttcttcag taattcgatt gcatcatcgt
    19861 aagtaatacg agggaatggc aattttgtat aagtttttaa gacttctttg tctcgtccta
    19921 gtacatctaa tgcgtattcg caatgatcta aaacattttg tactaagaat gctacatatt
    19981 gttcctgtac ttctaaactt tcttcttgat gagtgaaagc catttctggt tcgatcatcc
    20041 agaattcgat caaatgacgt cgtgtttttg atttttcagc acggaaagtc ggaccgaatg
    20101 aaaagacttt tccgaaagcc atagcagcag cttccatgta taattggcca ctttgagata
    20161 aataagcttt ttgatcaaag taatttgttt cgaatagatc cgtagtgcct tctggtgcag
    20221 aaccagtcaa gatcggcgga tcaattttga caaaatgatg ttgattaaag aattcatacg
    20281 ttgcacgaat gatttcattt ctgatctgca taatcgcatg ttgtcttgaa gaacgcagcc
    20341 ataaatgacg atgatccatc aagaagtctg ttccgtgttc ttttggtgtg atcggataat
    20401 cgtggctctc gcttaccact tccacatttg taattccgat ttcataaccg aattttgaac
    20461 gactgtcttc acggatttct ccagttacta acacggatgt ttcttggtgt agatttttag
    20521 ctgtttggaa aacttcttcc gacacttcgc tttttacaac tacaccttgg aaaaaggctg
    20581 ttccgtctct taattgtaaa aatgtgattt ttccgcttga tcgcttattt gcgacccaag
    20641 cgccgattgt tactgtttct cccacatggt ttttcgaatc gatgatttga atttgttcca
    20701 cgtatgactc tccttttata ttccttgaat ttcttcagga ttaattttga cttttactct
    20761 caataaattg cttgattctg cgtaccgctt cttctaacgt agcgcgatca gtagcataac
    20821 tcatgcggac attttctggt gccccaaagc cttcgccagt cacaagcgct acccctgttt
    20881 cttctaaaag atcttctacc cattgtgtga cattttcata tttacacatg cgtagcgttt
    20941 cttttacatt aggaaaaaga tagaaagctc cttgcggctt ttcaagagaa acacctggca
    21001 gttctgccac aagcggatat aacgtattca ggcgttcttc aaaggcgttc cgcatttctt
    21061 ctactgtatc ttgctcacct ttcaatgctt caacagctgc atattgactg actgctgtcg
    21121 gattactggt tgactgggaa gcaacagcaa tcattccatt gatgatctca gatttcccca
    21181 ccgcataacc aatgcgccag cctgtcatcg catatgtttt agacacgcca ttgatgatga
    21241 tggtctgatt tttgattgct tctgaaatcg ttgcaattgg agtaaactca ttgccattat
    21301 aaactaaacg accataaata tcatcagcaa ctatcaaaat atcatttttt actgcccatt
    21361 caccgattgc ctgaagttca ttcttgctat aaatcattcc agtcggattc gatggagaat
    21421 tgatgattac ggcttttgtt ttttctgaac gtgcttgttc tagctgttca acagtaactt
    21481 tccagctatt ggattcttcc cctttcacaa agacaggaag tccttctgcc agttttactt
    21541 gctcaccgta actgacccag taaggcacag gaatgatgac ttcatcttgc gggtcaagga
    21601 tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc tgttacgact gtttgtgaag
    21661 gttcatagac aagtccatag tttttcttca gataatcaac gattgcctgt cgaagctctg
    21721 ggattcctgc tgttggtgta taatagctag ctttcccatt gcggattgct tcgattgctg
    21781 cttcttggat gttttctggt gtcgcaaaat ccggttctcc cacagtcaaa ctcagcacat
    21841 ctctgccttt tgcttttaat gccttggcct ttgccgcagc tgccaaagtg acagacggtt
    21901 ctaatcgttt tgttcttttt gataactcca tcccattcat tcctttacct tttaaattcc
    21961 cttgattgtc ttgacttcat ctccagattc aaagccaatc aggtaataat tcagtttccc
    22021 atttgtttct tttcctacta cttcccacac aggctgatca tcatacatcc ctaaagcagc
    22081 tttttcgatt tggatttcag gatgggccgc agcaattgtc tgttttgctt cgttttcagt
    22141 cagtcccttt gtttgatcca atacttttac tttttcacca gatttaggaa tgataacggc
    22201 gatttctttt cctttatcat ttgtacctgt cagtgaaaag tatgtcttct ttcgagtaaa
    22261 ccaataaaaa tgatcggctt cctcaagatt tgcatatttc tttgcgattt ctactgcttc
    22321 tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa aaaatcgagc tgatcacgat
    22381 gaccgctaat aaaaatacga tcaagccaag taacacgcga ttaatcgttt tttcctttgt
    22441 ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt ccttttcatt atagcagatt
    22501 ttaattatga aaaaagacag ctcctctaac ttccttcttc atttttcttt aagaattcat
    22561 ggatgtcctg atagatttcc tccatagcta gctctttgat cggtactttt ttcggtaatg
    22621 catggatgat ccgtgcacca tattttgcag tgactagtct tcgatccaaa ataagcaata
    22681 cgccacgatc tgtctccgtc cttatcaagc gacctaatgc ttggcgtaac ttcaaagctg
    22741 ctttaggtac ggattcctgg taaaaaggat tgatcccctc tgattctaaa taagcgttcc
    22801 tagctttgac catcgggcga agcggattat cgaagggtaa acgtgtgact acaacgatct
    22861 gcaaagcatc cccaggcaaa tctacacctt cccaaaagct gtcagcgcca aacaatacgc
    22921 ttttttctga caaaatgaag cgtttcaaaa gcttctcccg gcttccgcca aacccttgag
    22981 ctagtatttc tcgtcctttt tctagcatag acagatgcat tttctgatag accttctgca
    23041 aaacatcatg agaagtgaat aacacaagta ttggccgatc ttcttgttcg atcagacctg
    23101 taagtgctgt ctctaaataa tcgatatatg cttgattgct gacttgatgg acggcaggtg
    23161 cctcttttgg cacatagatc cttgcctgtt tctcataatc ataaggagag gcaatcactt
    23221 taagaggtgc tgcttcaatg ccaagccgct tagagagata gtgtcgatta gggccgatct
    23281 tcagcgttcc tccaatataa agaatacgat catatcgagg ataccaaaca gtcgacggca
    23341 acatagccgc ttgaaaatca tggagatgaa aaatcatctg ctgcgctgtg ttcccaggaa
    23401 cgaaccaatg gatcaaatga tctcgccagt cttccagcca ttgatccatc agcaagtact
    23461 gcttgtctaa ttgatcaaat aagctatata aacttgctaa atcgatccgc atctggtttg
    23521 tccagctttc ttggataatc tcaaaagtca gacgcatttg tgactgtagc tgctggatct
    23581 cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga ttccagtggc agctgatcca
    23641 acatctcttt tgtcatcatg acttcttctg gatactgtcc gttaggttgc ttgccgctca
    23701 ctaaactcat taatccttct gccatacaaa tctgtgcttc gcatagcgca gaaagttctt
    23761 ctcgataaat cgataaccag cgtaaggctt catgttcttt cggtaaatag ctttgtattc
    23821 ggtcaaacag ctgatttggt tcttctaatt gctggatttg tttatggaaa tagttaatac
    23881 ttaatcgttt gtcatttact ttttcagcga tttccggcaa atgatgtact tcatcgatca
    23941 acaaaaatgg actagctgga agcaatggtt cttttcgctg tgtttcttgt attaaaaacg
    24001 catgattgac aatcaaaaaa ttactttgcc tgattttctt ttgcaagaaa cgaacaaagt
    24061 cttgttcgta aaatgactga tttcttgcta aaaatccaat acctctgtgc gcgatatctg
    24121 caaagaatga atggttcaaa tttgttaaat gtaattcatc caaatcaccg gtcttcgttt
    24181 gcgtcagcca aactaagacc gccatttgat acaaagcata ttgtttttgt tctggcggtt
    24241 ccacaagtgt gcctttaaaa cgctgtaaat caatatagtg gcgatagctt ttgataatta
    24301 caggttgtat gggctgatct agcaattgat tcagcaatgg aatgtctttt tctatgatct
    24361 gctgctgcaa aactagcgaa acggtactga tgacagcggg tttttcaggt gtagccaaat
    24421 aactcaatgg cagcagataa ccgattgttt tacccattcc tgtagctgct tcgatcatca
    24481 aatcttttga ttcatctttt gtgaaatggt cgtagaccgc attcatcagt ctgttctgtt
    24541 cttttcgata catcagtgtt ttaccaaaca ttttttcttt tgcttgtttt tttcttggat
    24601 atgtccgctc gccataatgg acggatgtga atagttccac ttcttttttc tgcaaagcta
    24661 gcccatcgac gatttctaat gagggatcaa gtggctctgg tttttctttc atttcttcaa
    24721 tcacatgata aatgaaacga ctcgtatcca tacctgtgtg tctacttaat cgcgcaatct
    24781 gctctaacgt gatgattggc aattttctca tccgttcttc gatcagcaaa agaagttgac
    24841 ccgtcacttc ggcatcacta tctgcctgat gaggattctc atgaataaat ccaaggcttt
    24901 ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa gaaaatttgt gcaagttcta
    24961 ctgtatcgat gcctggtatc ttcaaactag gaagtccgca tcgcatgagt tcatggttca
    25021 aaaaattata atcaaaataa atattatgcg cgacaaatat ggtgtctgcc aaaagattgt
    25081 aaatcgtttg ggcgacatct tcgaaataag gcgctttttg gacgcgttga ttcgtgatcc
    25141 ctgttaaatg ctggatttgt tttgaaatct tccgccctgg atgaatatcg atcgaaaaac
    25201 gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa ttggatgatc cgatcttctt
    25261 ttggattcgt cccagtcgtt tcgatatcaa cgactgcata agttcttggt ttcaaaatat
    25321 cttcctcttc tcctgcctct aatgttcttt tgaaattata ctacaaagtg cagaaaaata
    25381 ctctcatcgc tttttaaaga aaatagacaa aaacgcccag acacgcaaat gtctgggcgt
    25441 ttatttttta gtataggtta attaagcttt agtaacgttt gttgcttgag gtccgcgttg
    25501 gccttcttca acatcgaaag ttactgcttg gccttcttct aaagttttga atccgtcgcc
    25561 ttggatagct gagaaatgaa cgaatacatc gtttccgttt tctgcagtga tgaatccaaa
    25621 tcctttttct gagttaaacc attttactgt acctgtttcc ataataaaaa tcctccttgt
    25681 gtatcaacac atattttgca attacttgaa tggtgtatat ctggaagatg tttatttgaa
    25741 acaagctacc acagattacc gaacaaaaac tactcctata gtatatcata ccgtttacaa
    25801 aaaagctaga gtttttcgac tttttttatt aaaaaaagtt ttctcagcga ttacataaag
    25861 tgaaaaaccg aacttttttt aaaataaacg acatattgtt cagttggtgt ttttttgctc
    25921 tgatgttctt ctttaaacta aaaaaattat tctttctgac tacttatcgg ttctgtttca
    25981 acggtcgagg ctggggaaga ttctttagta ggtctgatgt tctcatggta tttctgatag
    26041 cctatgacag ttaccagaag aacaaggcaa accaatacga tcaacgagat tagtttttct
    26101 tttttgctca tatctatacc tcataaataa caggatgatg tccatcatat ttctgagtat
    26161 gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg ccagcaactt tcataatcac
    26221 aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa agaccgttct tctgtttcag
    26281 gaatcgcaga atcaagatct gttgtctgta cataaacatt tttgtacaga cgtgtgcctg
    26341 taataggaga ccgctgtgtt tcttcagcaa aaactggctg acttgttaaa cttagggata
    26401 gaaacagcaa acaccataac agtctttttt tcataaagac ctccttatcg ataagttttt
    26461 cccaattaaa atcatatctc aagaacgccc gttattcaca ttttgttcat aaatgatgtt
    26521 ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc acaacctctt tttt
//
LOCUS       DAPBBR010000037        26047 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPBBR010000037 DAPBBR010000000
VERSION     DAPBBR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.037"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..208)
                     /locus_tag="RD488_001759"
     CDS             complement(<1..208)
                     /locus_tag="RD488_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7657835.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSD"
     gene            complement(307..621)
                     /locus_tag="RD488_001760"
     CDS             complement(307..621)
                     /locus_tag="RD488_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657836.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(689..1183)
                     /locus_tag="RD488_001761"
     CDS             complement(689..1183)
                     /locus_tag="RD488_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657837.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1176..1490)
                     /locus_tag="RD488_001762"
     CDS             complement(1176..1490)
                     /locus_tag="RD488_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657838.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1706..3097)
                     /locus_tag="RD488_001763"
     CDS             complement(1706..3097)
                     /locus_tag="RD488_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDT7657839.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3082..3693)
                     /gene="mobC"
                     /locus_tag="RD488_001764"
     CDS             complement(3082..3693)
                     /gene="mobC"
                     /locus_tag="RD488_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDT7657840.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3697..3894)
                     /locus_tag="RD488_001765"
     CDS             complement(3697..3894)
                     /locus_tag="RD488_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657841.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3885..6563)
                     /locus_tag="RD488_001766"
     CDS             complement(3885..6563)
                     /locus_tag="RD488_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657842.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(6550..6768)
                     /locus_tag="RD488_001767"
     CDS             complement(6550..6768)
                     /locus_tag="RD488_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657843.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6844..7896)
                     /locus_tag="RD488_001768"
     CDS             complement(6844..7896)
                     /locus_tag="RD488_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7657844.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(8049..8375)
                     /locus_tag="RD488_001769"
     CDS             complement(8049..8375)
                     /locus_tag="RD488_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657845.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(8387..8587)
                     /locus_tag="RD488_001770"
     CDS             complement(8387..8587)
                     /locus_tag="RD488_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657846.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            8710..9312
                     /locus_tag="RD488_001771"
     CDS             8710..9312
                     /locus_tag="RD488_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657847.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            9367..10533
                     /locus_tag="RD488_001772"
     CDS             9367..10533
                     /locus_tag="RD488_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7657848.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            10938..14165
                     /gene="fss3"
                     /locus_tag="RD488_001773"
     CDS             10938..14165
                     /gene="fss3"
                     /locus_tag="RD488_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HDT7657849.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHKYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIDNEFTPGYEKN
                     PLPDMPEKAKLVSVLWKKAGTDVDTHIVAQKMIWQEVNGYTLHSIKRLNGSAVNIAAI
                     EAKINQAIADYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAQEKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPLKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGTEYTL
                     FTAKDGKAVKWSEAFKPEMVKGTKASDETVTLALDEKNQAAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQIIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVNCTVERHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIEYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGTINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSLTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            14278..14592
                     /locus_tag="RD488_001774"
     CDS             14278..14592
                     /locus_tag="RD488_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7657850.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            14605..14979
                     /locus_tag="RD488_001775"
     CDS             14605..14979
                     /locus_tag="RD488_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7657851.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            14980..15333
                     /locus_tag="RD488_001776"
     CDS             14980..15333
                     /locus_tag="RD488_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDT7657852.1"
                     /translation="MKIMEINVEHILDCLDQYGKGELTEEQLTNALTYDEKMFLIMHQ
                     GLLEVGNDAKEDFDIPDWLGEEESFFMVVEVNESLCRQAESVLEEIGVEMPDAIEGFL
                     KQLVETKQLPVVVND"
     gene            15402..16418
                     /locus_tag="RD488_001777"
     CDS             15402..16418
                     /locus_tag="RD488_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7657853.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLSALFIGWMGVFYFPELRQFGL
                     SKVSFSTIEIAWSMKDLVCLLGSLALSGSMMLLYIHFFPDHWRSLWNRQKLARMILEN
                     HWYEVKQTQSDGFFKDLNRSRTKETISYFPKVYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISKCVEDFYERMMARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            17012..18886
                     /gene="ltrA"
                     /locus_tag="RD488_001778"
     CDS             17012..18886
                     /gene="ltrA"
                     /locus_tag="RD488_001778"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7657854.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTKDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            18958..19341
                     /locus_tag="RD488_001779"
                     /pseudo
     CDS             18958..19341
                     /locus_tag="RD488_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            19419..20093
                     /locus_tag="RD488_001780"
                     /pseudo
     CDS             19419..20093
                     /locus_tag="RD488_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            20086..20250
                     /locus_tag="RD488_001781"
     CDS             20086..20250
                     /locus_tag="RD488_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657855.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            20326..20553
                     /locus_tag="RD488_001782"
                     /pseudo
     CDS             20326..20553
                     /locus_tag="RD488_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            21314..23164
                     /gene="ltrA"
                     /locus_tag="RD488_001783"
     CDS             21314..23164
                     /gene="ltrA"
                     /locus_tag="RD488_001783"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7657856.1"
                     /translation="MKKQKLRNAEYYDFQTIQDQLYSQSKHGKIFKHLMDIISSDQNI
                     KLAYRNIKKNSGSHTPGVDGKNIENLAKWQDDALIKHVKRKFQWYEPQAIRRVQIPKS
                     SDSTKTRPLGIPTIMDRLIQQCILQVLEPICEAKFYDKSNGFRPNRSCEHALAQAEKN
                     MQLSKLHFVVDIDIKGFFDNVNHGKLIKQLWTLGIRDKKLICILSAMLKAEIAGVGFP
                     EKGSPQGSIISPLLSNVVLNELDWWISSQWETIPTKKEYKQCDGHSSGRLQALKKTNL
                     KECRLVRYADDFKIFCRTRSDAEKIFVATEKWLKERLGLNISPEKSRIVNLKKHYSEF
                     LGFRLKVVRKGKYPNGNPRFVIRSHISKKALKNIHLSAKKRISNLQNLSDDRECYKSV
                     QNYNIFVLGIHNYYSKATHASLDFAKIAFPIRKSLKGKLQGNFSKEKGICSSLIENRY
                     GKSRQLAYVYGFAFIPIGYVQHRAPLDKKREINQYTAEGRELIHKQLGSSINPDLLSY
                     LMENPIKGKSIEYNDNRLSLFCAQKGRCAITGDDLTIGNMHCHHKLSLKLGGTDEYKN
                     LAFVTVEIHRLLHATNLKIIIELVQKLNLSRTQLEKVNKLRKKIALPIIE"
     gene            23299..24214
                     /gene="dcm"
                     /locus_tag="RD488_001784"
                     /pseudo
     CDS             23299..24214
                     /gene="dcm"
                     /locus_tag="RD488_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            24204..24494
                     /locus_tag="RD488_001785"
     CDS             24204..24494
                     /locus_tag="RD488_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657857.1"
                     /translation="MIYDELVGEIYWVIGKIQSDPELEEQLRRLNFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            24752..25936
                     /locus_tag="RD488_001786"
     CDS             24752..25936
                     /locus_tag="RD488_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7657858.1"
                     /translation="MVQQNLDYRLLKDRRNQYGVSQNKLATACGLSRPYLNQIENGGV
                     TTSTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVQKIVQEILHLKFDYMLHED
                     YAFYSYQEQYIMGDIVVMLSHEEEKGVLLELKGRGCRQFETFLLAQKRSWYDFFDDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDKSETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIEGTTFSIINRYLRFTDKVEGKRRTNWPLNERWGRFIGRNRKEIQLTSDPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYILDMVQNAQLSDRHKKILEQQSMAIENL
                     II"
     gene            25933..26031
                     /locus_tag="RD488_001787"
     CDS             25933..26031
                     /locus_tag="RD488_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDT7657859.1"
                     /translation="MKRGSSMLGVTVMCLIHTSAAADRVMERKVIK"
BASE COUNT         8537 a         4550 c         4809 g         8151 t
ORIGIN      
        1 aatcagatac ataagcccat gtacccgttc gttgtaaata aagttcttct tgtaacaact
       61 cccattttct cttagaaatc ataatgacgc catcgttcaa tccattttta gaatccctag
      121 taatttctat ttcagaattt gaatgaacta cttcttgcaa cactttacct atattttctt
      181 tgaagtttgt tggagtaata gtatccaaaa tgaatacctc tcttctctat acctctatta
      241 tgaagtgccc ataaaataaa gcaagcgttg aggaataatt ctatcaacac ttgctttatt
      301 aagctttcat tttgtagttt gactaaaacc aataatctta tttctaaact ctcgaaaaac
      361 ttcttgtggt tgataatagt ctggatctat ttcaaatgtt tgtgagaata attcattgaa
      421 tttttctact gaaataatga ttttaccatt cttctctcga ctgttttcta ttatttctgc
      481 ttctaattca aataaatcta gtgacgaact aaaatcataa atcatgtcat attgaataaa
      541 aaaatcaaga aaaagttgct caaactcttc cttatttatc actaatgttt caaacggaac
      601 aactttattt tcctcagcca ttctcccagt tccattttca aaaatcacaa aactgatatt
      661 accttaaaaa ctactaacaa aataaaactt ataaagtaaa tggcaaccca actatgtaac
      721 cattctctct acgtactacg atttggtagt cctgcctttc aatcggtaat tcataatagt
      781 aatttactgt ttcttctttg ccactttcaa tatactctgg attatccaat atcatatcat
      841 actcataaag ttcttcacca tccttatttt caatcgacca ttgttgtgga cgtatcggat
      901 tttctgtatc atttataagt gtataggtca cttgtaatac acgatcatgt tgtgcaaatt
      961 catttctttt ttcggtcact tcaatatttt taaatgttag ttcaacccca tctgcctgat
     1021 aagtttcacc tatttttaaa tcttttgtta caatttttat tggcttttct tctggaaaat
     1081 gtctggcttt aattgttaga taacttccaa aaagaatcaa tcctagtagc actaaaagaa
     1141 ttcctttaac gagccactga aacgggaagt aaactttaaa catctttttt ctcctccgtt
     1201 ttgtatttgt tttttagaga atacgataac ttttgatcaa tgtcatccag cttttcaatt
     1261 acttcattac ttatcattga ttctagttct gaaatttttt gttcaaattt aatgctttca
     1321 ggatcattaa atttattatt tgatggacta gctaacactg gtaaatttga aaccataaca
     1381 cgaaacatat ttgcctttga accaaaaatt cctttgtttt ggttgtaaaa attgttgaat
     1441 atttctttag tttcttctga agccgagact ttaaaatatg gatagttcat ttttttcttc
     1501 cacctttctt tttttgggag ggagtctgta gggagcttgc tccctcagag atttacccgc
     1561 catctgactt gccagaaagt agcctagcgt gagcggggcg gattgactgg caagtagatg
     1621 ggtagctggc gtatgtccta aaaactgctt ctttccaagc aactcttcat aggcaaaaaa
     1681 ctggaaagtc cactaacaag cccattcaga attccatttc aaaattttgt tgcctttttt
     1741 gctgattttc aatcatttgt tgtgtgaatt cataatcctt tttagcacga tacattttta
     1801 catcgtcatt cattatgcga ctgatttgat agtgaatctg tttagcagaa ggtgtatgag
     1861 aacaattttc aaaacccttt gccggtagaa ataactcttt ctgatcagtc tttttaatag
     1921 aaattgtttt acttttcgca ctacgtaaag tttgaggatt cacatccgta tgaagtttaa
     1981 tcgtgtattc ttgatcatct tctaaagaca ttgtatttac aaaatgcttg tctacctctc
     2041 gcaagaagtc atcatattta atgaattttt catcgccttc acggtcgcta aattgctttt
     2101 gtgcgatgga atctaattcc acaaacggta catttaactc accagttttg taatttactc
     2161 cactaattag cgacataact tgctctcttt ccatattaaa aaaatttttt atatgtgatt
     2221 cttctaaatt cttttcaagt tgttcagaaa cagattcaaa tgaatatctt ttccctaact
     2281 ttcttgcact aaaagtacgt tcgacatact gacttttttc ttttctagat tgtttatctc
     2341 ttcctaaagt aattaactca cctctacgct catagaaatt tacaccttgt ttgtaaagaa
     2401 catagccaag tttgttattt gtttttgaaa attgataaac ttcaatgtta tattcttttg
     2461 ccaaatgatc cgaaaaatct tcaaaagaat tcacttcgca tttttccaac gttgcttcga
     2521 tcgcattttg cacaaactct tgataattaa tttttccata tttcatctta gaaggatcgt
     2581 ttgaataaag attggttctc ttttctaagt tttcatagta ctcattattc actgattcaa
     2641 gaccatgttc attgaggact tgatcgttaa tttttcgcat tagttctaaa tctttagggt
     2701 caatacgcaa ccttttacat gtttccatgt taatattatt aatgacaaga tgactatgaa
     2761 aatgatcttt atcattgtga cttgcaacaa tgatttgcga atttggaaaa gctttctctg
     2821 caaattcgac agctatttcg tgcattttat caatacttaa ctctttagaa gtactcttat
     2881 caaacgaatg aataacatga aacgcttgtg ctatatcttt agatttattc atcttggtac
     2941 gtactaaatt catttcttgc agtgcttcct cactatcatc actacaattt attcctgaga
     3001 ctgcaacaca tttttctttt tttgaaggat tagctgcata ttgtaatagc gaggataaat
     3061 ttttcttgcg tcctttcgat gttatagtag ctcccaaagt tgtttcacct catcttttaa
     3121 acttgcaata atctgaattg agtgaattaa attccgatca actttttggg aatactcttc
     3181 tttcgtaccc ggtctagttt gcttttctat ccaatattcg aaatattctt tttctacttc
     3241 tgataattta aaaaaagagg gggcactccg attggactcc aaaaaaatgt catctggata
     3301 actaatcatc aacttttttg ctatgctatt cgcaagttca tctttaaaaa tgttgtaacg
     3361 gctagcatca aaactaaaat gtaggctctt ttctttttta tcttcagatt cttctctaaa
     3421 atatttagca atgatattta atgcctttac cgcttgattc aaattgttac caatttgatt
     3481 taactgtttg gttaaaacta ccctatcatc ttcagctaac aacggcggtt catatttgag
     3541 tccctttaac cgctcacggc aaacgtctgc tctagaaatt cccctttgtt ttgcaatcaa
     3601 tgtcagttca agataagtct ttttatcgac acgaaaattt aaggcctcac tatgtttgcg
     3661 atttttttcg tacatttttt gtttatcatc cattgattat cccctcacat ttttttctag
     3721 agagcaacat ttgaaattgc tctctatttc atttttcatc tttaattctt cttgaatcat
     3781 cagttcaata taattagtga ccgtgatttt ttcatttgtt gcgttcttta ctgattcaca
     3841 taattcgtca agttctaaga aatcatgcgt actaatcttt agaattaatt gcatgacaat
     3901 cccccccttt tatttcttaa taaattatcg aaaagtggat taggatcatt aagtgtatct
     3961 ctgaataact cattgtcttc ataagtgaat cttcgtcttg attttgatcc cttatcattt
     4021 tcacggattt cactatcaat aatcactgtt tcatgatttg aatcaaattt tttcgctgac
     4081 tttctgtctt caacgatatt gattttttgt gttttttctt tcatttctcc actatctttt
     4141 tgaatgttct cccgaacatc tactgttttg aatccttgac tacttgtaga actttgtaca
     4201 ttttctcgga catctactgt ttttggttga cttgcactgc taccttgcac attctctcgg
     4261 acatccactg atttaaaccc ttgactactt gtagaatttt gtacattttc tcgaacatct
     4321 actgtttttg gttgacttgt actgctactt tgcagatttt ctcgaacatc aattgtctta
     4381 gtaccttgag catttgaaga actttgtaaa ttctctctta catcaacatt ccgtccaaca
     4441 tgaccattca gtgaaccttg aatattttct cggacatcta ctgatcggcc accatgacta
     4501 cttgtagaat tttgtggatt ttctttgact aatttttcta atcctgtatt tgaattttta
     4561 gcttcttgaa ttctttcttt ggtcaacgct tcttttccgt caatattagc gcctgtccgc
     4621 ccttctacac gtttccttaa cattatttcc tcgcgattca ttgcttcagg cgtgtatttc
     4681 gcttcatgac gcttctgatt aattaattct tcagcagact tagcttgacc gtgcatagca
     4741 tttttacgtt cttcaatatc ttgttggact ttttgctgaa ttgcgcttgc aggattatta
     4801 ttcgattcag cattattttt cattgcttca cgcatacgtt cagaactaga cataattcta
     4861 tcggcatttt caactttagc accatctttt ctatctgaaa gacgtgttgg cacggaatca
     4921 gcatattttc cagtttcatc ttctttattt ttagctaaca taggtttgct atttttatta
     4981 atagcggaca ctgtaccatc atctaaacct tctttaaact tattcttggt atcattagct
     5041 atatcacgca tactcttaaa tggttttgtt gctctttcac tagccattgt agctccatct
     5101 gaagctaaac cggataatcc acgttcatgg gcatatccca aagctcttcc agttttgcca
     5161 gctttttttg atagagtttc gccgaaattc ttttctggtt ttcgatcttc tccttctccg
     5221 cttcctttag cacgattaaa tccatttgat ccttttctaa acagcattgc gcccattcca
     5281 aaagcagaag caagttgccc atagccttct ttgagtccaa tatcaacacc aaagtatctc
     5341 atgactgttc cactgccttt gattaaaaca aaaacggcac agatataagc aattgttttt
     5401 ataaaaatat ttgttgagat accttgtcct gagttcagaa aattgataaa catagcaaac
     5461 attgataacc caaatccttg aaacccaaca gttaagtaac attgtagaat atctgataga
     5521 acaacttttg aacgctgtcc tgtctcaata tctgttgcaa aaacaagaac acctaacaca
     5581 cgtttaaatg caagttctag tattgctgta atgatcacaa acgcgctgaa cacataggcg
     5641 attgctaacg ctgtcaaccc aattgaaatc ccccatagat ttgcttggta tcggtaatag
     5701 cctgatttca agctatcaga aaatgttgat aagaagttgt cagaaaactt tgtagcaaca
     5761 aattcattat tagaattttc aactaattca taacgaagat tgtccgcaat tggattttct
     5821 ttttccaatt tatcaatcac tttatccgtt aacacttgtg tgagatccgt ctgttgaaaa
     5881 ttttttcgtg ttaaattatt tcgatcctcc gttttatcaa tgcttgagta ctgatctgtt
     5941 ttattaatat atgctaaatc tgttactcct tgttttatca atgaccaagc gactccgtca
     6001 tctgaatttg taatcgtagt agagtcctta taaaatgttt tagcaaattg aataccacta
     6061 gaaatcatgg ttggcattaa aagtattaat gctatagaca tcactacgtt cattccaacc
     6121 gattttaaat ccactgttcc ttttccagta atcattttgt aaccaacaaa catcaatgaa
     6181 aggatcatta atccaatgac aattgtattt acggctgatt gataaacatt atttagccct
     6241 gtactttcaa tgaaattgaa caaatccagc acatctggaa tcatattttg aatcgaatct
     6301 gtcacagtaa acatgccttt taccacagcc catccgagcc aaatcccgaa ctgactaagg
     6361 aaatctccat tgtacttttt taggtaaggt ctataaagag aattattcaa aaactctgtt
     6421 tgactttttg tgtcatcaaa ccaattgaaa atactcgcat gagcaatatt acttgtaaaa
     6481 ataatcatag ctatcagaac aagaaaatta acaaccaacc aatttatttt tttattggca
     6541 atcttttttt caattatttt catcgttacc tcccttagcc cattttctga ggctctcaga
     6601 gagcttctga gccatttttt gattaattat gacatgagtt acacaattat cattttcagc
     6661 tcttaaatcg agaactatag tgttgaagca aatagtctcg attaattcga gactatctgt
     6721 attttgatct agacaccaaa cttgatctat taaacgattt ttaatcaaaa taacccctcc
     6781 tatattcaaa gttctcaaat gaagtggaga tacccctcca tttcatttga ctcaattcta
     6841 ttcttattgc ttatctattc cttcgctgat ttgcaattca attagttcta acgctttatt
     6901 ttttagagaa gcaaagatat aatcgtcttt ttgtttgata cgatgatctg tttttgctct
     6961 tcgtatcaag tcacgtaaag tcattgatag ctgttctcta acatgatcta caaaatactt
     7021 gttattacaa atttcataga taattttcag ttgaattttt tgttcttttt cagcagatct
     7081 aatcgcatat ttgaattttt tgtaccagtt gtcgaattga cgataatcac tattgctagc
     7141 cagttttaag caattcacaa tactttctcc ccatatttgt ttaagaagat tttcttcaat
     7201 aaatgtttcg atcaattctt catctaattt attattttta gttgaaagtg attcaagaag
     7261 atcatcatta tgtgattctt taatatcttt actatcttta taagacttat ataattctag
     7321 ttcatttttt gaactatcag caaaattgtt tttgtctctt gttttcattg atgtgtcgca
     7381 tagttcaaat tttgaattat caacagaata ttgatttgtt ccatagttca aattttgaac
     7441 tatcaagttt ttttgtctat tttcttgatg ggttatctta ttaattttat aaacatcatc
     7501 tttgcacaga acaggcttta acaaataata aaaatttggg aacatttgca ttttactttt
     7561 attgaagcca ttttttcttt tcacaagaag tttaactttt tgaagttcat ctagtgctga
     7621 taagattgta ttttttgaca ttcccgaaat ttctacgaga tttttgattt caaatatcaa
     7681 aaaaattttt tgattctcat catacaagtt atttttcaat gaaagtctat ttctatcttt
     7741 tagtaacata taaactaact tagaacttag tttcattttc ttatattttt catttacgtt
     7801 taaaaaaata ggatattgat agtataattc tgcatatata tcagaattag aatagccttg
     7861 cttttcaact aagctttcaa cttctttttc attcattgtc acacctgctt ctgattttat
     7921 ttgctataat agattcaaat aaagttttct cagaacttta ttattgagtg ttcccccgat
     7981 ctgcaaactg acgggaacac tctttttaat tttttctact tcatcaaatt taaaaaacga
     8041 ggtgtttttt aaatttgatg actcaatatc cattttttgc attcttcttt tgaaaacaac
     8101 tccatttttt ctaataaaat aactggcaat cccattcttt taaatttcaa aaaagttgta
     8161 tatgatacat tcaaatattt agccatctct tttcctttta gaaatggtct ttctaatccg
     8221 gtatcaattc ttgcttgatc aatagcctct tttgtcattt caaaaacata atttttcaat
     8281 tgattcgttt gttgtttatc taacattact gtaattcctg catccattat ttttctcctc
     8341 tcattttcta tttcttcaat cagccaactc gccaagttgt atttatttag attttcaaat
     8401 cattaagtaa ccaatttacc aacttttgat aagtagatgc tctaatactt tctttgctcc
     8461 cattttcgat tttgacatat gttttccgat ttatacctat caattttgct gcatcgtttt
     8521 tagtaagtat aagatcggct ctatgtcttc ttaagcttct aatgaattga tcattaagag
     8581 ttatcattca gcgcctcctt tcaaattatt cactttgtgg tttttatctt aataagcaca
     8641 ttttaaacca caaaacgagt aatatcaatt aaaatattac tcaatttgtg gttttcatgc
     8701 tataatagtt tggaatttac tatagggggc gttactttga atagaataaa attttatatt
     8761 gattccagta aaaagaccat taaacaaatt agtacagaaa ctggtattaa ctatacaact
     8821 cttacgaact attaccgtgg tgagcgaaat cctagaaata ctgaaacatg gaatatcctt
     8881 gctgattatt tccatgttcc tgtaagttat ttgatgggat tagacgaaac aaattccata
     8941 gaacaaccta atcttgatag aataaaaact gctcgtttag aaaaaaagga caaaatagtc
     9001 aagaatattg ccagtcttga ctcagattat tttactgaat tatctaatct atacttttcc
     9061 atgacttctt tacttgaagt caaacttcaa gaagatgact ccgactttct ttttttaaaa
     9121 agtattctag aggactcctt tgaatacacg attctatttg ccaaacaaaa gaagtttatt
     9181 aataaagctt taaacttaaa tatcgatgaa agaaaagagt tagaatctga gttatttggc
     9241 aacttaaccc aagtacaggt taacaatcta aaaagagaga taacagctcg attaatatca
     9301 aaacttcaat aaaactaatt attcaatcag ccaactcgcc aagttatcag attggagaga
     9361 ttagttatgt caatacaaaa gtacacaaca aaaagcggtg cacgatatag tgtccgcttg
     9421 tatgttcgta aagatgaaaa tggaaagcaa gaatactatg taaaaaaagg gtttaaaact
     9481 gaaaaagaag ccaagttaca cgaagcaaga aaaaaggtcg agattgaaga taccggctat
     9541 cataagcctt ctaatgactt gtttataaca gtgtatgaag aatggttgcc ttcttatagg
     9601 aatcgtgtac aagaaacgac atatcaacgt acaaaagacc ttttccgctt gcatatacta
     9661 ccaaaattcg ggaataagtc catttctaag attactcctg ttcactgtca gaatgcagtc
     9721 aatgaatggg ctttaaaatt caagaatatc aaacagctta agtcttacag ctctcaaata
     9781 tttgagtatg ccatttttgc agagctatta caccgaaatc ctatggcaaa tacaaatcta
     9841 ccaaagcggg aaaagaaaga aaatgaaaat tacttttcat tagaagaact aaaagctttt
     9901 tgggatattc tcaataaaga agagccttta aaacatattt taatcttcca gcttttgatt
     9961 actactggta tacgtaaagg agagctagct gctcttcatt ggtctgacat ttattttgaa
    10021 gaacagctaa tgtatgttag aaagagctat gcaactattc gaaatgaaga gaagaatgca
    10081 agaagaaaaa ctgtcaggat tcaaaaaaat acaaaaaata tatcttccga acgaatatta
    10141 ccaattgatg cacaaactat tgaaatgtta aaaatctgga aaaaagaaca agctcgagag
    10201 cttttgcagt ttggcataaa tacaaataca aaaaatcaac ttatctttac ctatgtaaat
    10261 gcagacggtg acattaatca acctttgcat gcggactatt caaataatat attgaaacgt
    10321 ttagagaaga aatataaatt taagcacgtt actattcatg gattccggca cactcacgct
    10381 actcttctac tagaaggtgg agcaagtatc aaagaaacac aagatcgatt gggtcataaa
    10441 aatgctgaaa ctacccttaa cacttattct catgttactg aaaaagctca acgaaatgcg
    10501 ttagaaaaat tcattgctta cactggttta taatattgtc attacctttc tcattaccag
    10561 aacgaaaaaa agacaccttc tcgcaatgag aaagtgtctg aaatcgttgg tataacaacg
    10621 attaacgttt tgaaaactgt gaagctttac gtgctttctt aagacctggt tttttcttcg
    10681 tatcattgaa taagtttgaa aaaccttgat ttataaaggt tttcccgtaa atatatttta
    10741 ttatatttga ttaaatttga aatgtttgtg ttctaaaatg tgttctaatt taaaggcagt
    10801 atatttcgta ttttagatta aatttttagg ctcattcatt ctatttagtc aataaatatt
    10861 ttaaaaagac tttataaaca aagatgttca agcgagcatc ttattttttt gtgcttaatt
    10921 tgaaaggaga acattttatg tataaaaaac aaaaaaagaa attatgtgta ttaactattt
    10981 tgagtttggc tgttcaagca attgtaggag caattgctcc tacgattgct tttgctgatg
    11041 aaattaccca tccacaaacg gtaaccgtag aactagattt agcacataaa tatgctgttg
    11101 aaggaacttt tagtgatggt cgtccaatgt cagaagtcac tgttccacat tatgctgtgt
    11161 acaacggcgt gaaacaagat attttctgta ttgagccagg agtcccaatt gacaatgagt
    11221 tcacgccggg ttatgagaaa aatccattgc ctgatatgcc agagaaagcg aaactagttt
    11281 ccgttctatg gaaaaaagcc ggtacagatg tagatactca tattgtggca cagaagatga
    11341 tctggcaaga agttaatggg tatacccttc actcaatcaa acgattgaat ggtagtgccg
    11401 taaatatcgc agccattgag gcaaaaatca atcaagccat tgccgattat cagaagaaac
    11461 caaccttcca taatagtacg gctaaaacag tattagggca atcgactact gtgacggata
    11521 cgaataatct gaatttgtca gagttcgatg aggttgtgga aaataccgca aacattgatt
    11581 atcgtgtgaa tggtaatcag ttgataatca ccccaaatgc caattcaaaa gaaagtggtg
    11641 tgctgacgct taagaaatct gctggtaccg gaacacctgt cgcctataaa aaggctggcc
    11701 aacagacttt aatggccggg gcgattgata aacctaatac ctacacaatt aaaattgatg
    11761 tggaaacgga gggttcttta aagatcaaaa aagtcgataa agaatcgggt gatgttgtac
    11821 caggaacggt tttccattta gactttggaa aaactttacc tgcaaaagac gtgactactg
    11881 acaaagaagg cattgctaca ttggatgaga ttcctcatgg tacaaaagta accattaccg
    11941 aaaaatcagt accggcgcct tatacgattg ataccacccc catgactacc accattaaag
    12001 caggtgaaac catttacgtg acttcaaaaa acgcacagga aaaaggtcaa atcattctgg
    12061 ataaaagcgg agttgaaaca gggagtgatc tttggaatga caattattcc ttagctggta
    12121 atacgtttgc cattcgcaaa gacagtccaa ccggtgaaat cgttcaagaa atgaccacgg
    12181 atgaaaacgg tcatgcggaa acaccaaaag agattgctaa tgcgttggaa ttgggaacct
    12241 attatgtgac cgaaactaaa gctagtcatg ggttcgtgaa tacgttcaaa cctctaaaag
    12301 tcgaattgaa gtatgccaat caaaccgtag cccttgttac cagtaacgta aaagggcaaa
    12361 atcaagaagt cactggcgaa accactttga cgaaagaaga caaagatact ggggataaag
    12421 cacaaggtaa ggcagtcttt gaggggactg aatatacctt gtttactgct aaggatggaa
    12481 aagcggttaa atggagtgaa gcttttaaac cagaaatggt aaagggaacg aaagcttctg
    12541 atgaaacagt gactctggct ttagatgaaa agaatcaagc tgccgttaaa cacttagcca
    12601 tcaacgagta ctactggcaa gaaaccaaag cacctgaagg atataccttg gatgaaacga
    12661 agtatcctgt ttctatcaaa aaggtagatg ataacgaaaa aaatgccgtg attacccgag
    12721 atgttacggc aaaagaacag attattcgtt ttgggtttga tttcttcaaa tttgccggat
    12781 cagccgctgg cactgccgaa actggcttca atgatctgac ctttaaagtg tcgccattgg
    12841 aagggaccaa tgaaatcaca ggtgccgaag atgaagcgac cacagcttat aacgagcaat
    12901 tagggtttga tggttatggc aagtttgaaa atcttcctta tggggattat ttacttgaag
    12961 aagtagaagc cccagaaggt tttcaaaaga ttacgccatt agaaatccgt tctactttta
    13021 aggaaaacaa agaagacttt gtgaagagtg agtatgtctt taccattacc gaacaagacc
    13081 aaaaacaacc aattaaaacg gtgaccgttc cttacgagaa gctgacgaac aaagcatttt
    13141 ctgttagttt gaaccgttta atgctctatg atttgcctga ggaagaagat agtttaactt
    13201 ctcttgcgac ttggaaagac ggaaacaaag aattaacttc tctggattct accgagctag
    13261 ttgataaatt gagttacaat ctacatgaaa tcaaagaaga ctggtatgtg gtagcgcaag
    13321 ccattgatgt ggatgcgaca aaagctgccc aagaaaaaga tgaaaaagcc aaaccagtgg
    13381 tgattgcaga aacaagcgca acgttggcga acaaagagaa aacaggaact tggaaaattc
    13441 agcataaatt aaccgccgaa caagttttaa ataaaactat tgtcttattc aactatgtgt
    13501 atgaaaataa ggaagctttt gaagcaggcg ataagccagt agcgaaggat gttagcttga
    13561 ataatcaagc ccaaactgtt aattgtacgg tggaacgtca tgtttcgatc caaacaaagg
    13621 cccacctaga aaacggttct cagaccttta ctcacggtga tgtggtggat atgtttgatg
    13681 atgtgtcgat tactcatgat gtactggatg gctcaaaaga agctttcgaa acaattctgt
    13741 atgctttatt accggatggt acaaacaaag aaatttggaa atctggcaag attgagtatg
    13801 aagtaaatga taaagaattc accaaaactg tgcttgcgaa aaaagtagat accggaaaat
    13861 atccagaagg aaccaagttt acttttgcgg aaatcaatta cgataaagat gggactatca
    13921 atggaaaaca caatgaagat ttgaaagaaa aatctcaaac cttaacacca aaagaagttc
    13981 caaccatact aagtacgccg aaacaaccgg aaacaccaac tgttccaagt ggctctcaag
    14041 aatctagtct cacagtgaag acattccctc aaactgggga gaaaaattcc aatgtgttac
    14101 tgttcattgg ttttactttg atttttgcga cggcgggcta ttatttctgg aatcgccgga
    14161 actaaggtga tgagatgata caagtaaatc ctaagaacca acgtgcgcga ccgcctccta
    14221 aaaaagtagt cgcgctattt ttgtatccaa aactaacaat gaaaagagga aaagaagatg
    14281 gaattgaaat ttgtcgtgcc agatatggct gaaacctttg gaaagttaag ttatgccgga
    14341 gaaggcgaag ttttaacaga aggatatgga cggaatacta cggtgattgg tcgcagttat
    14401 catttgtatt ccagtaagca acgggccgat gatattgagg tggtagtagc tgcggaagcc
    14461 ggtgaaaagg attttgatca agaccaaccg ctaaaagccg tgaatcccca tttggttgcc
    14521 aaaggctatg agattgagaa tcgtgggttt actgattacg tgttgtatgt tgatgattta
    14581 gtgaaagcat aggaggaaaa gaagatgaga ttaacagaag gtattgtcgt agattcaggt
    14641 ttaacatttg ggaagttgcg tttttccgca ttacgccgag aagtacggaa gcaaaatgag
    14701 gatggaacaa ttggtaatga ggtaaaagaa cgaacctata atttaaaatc ctctgcacaa
    14761 gggcgaatga ttcaagttag tatcccggct aatgtaccct tacgcgagtt tgcttatgat
    14821 gcagaggtag agttggtcaa tccaatcgtg gataccgttg ccaattatgt ttttcgagaa
    14881 ggaactaccg ttaattggtt tattaaagca gatgatttag tcttgaagcg gcagccgaat
    14941 caaggaaatc ctacgaacca aaatgaaaga aagaaatagg tgaagattat ggaaattaat
    15001 gttgaacata ttttagattg tctcgatcaa tatggaaaag gtgagctaac ggaggaacaa
    15061 ctcactaacg cattaaccta tgatgaaaaa atgtttctga ttatgcatca agggttactg
    15121 gaagtaggta acgatgccaa agaagacttt gatataccgg attggttagg agaagaagag
    15181 tctttcttta tggttgtcga ggtaaatgaa agtttatgtc gacaggcaga gtctgtcttg
    15241 gaagaaatcg gtgtggagat gccggatgcc attgaaggct ttttaaaaca attggtggaa
    15301 acgaaacaac ttcccgtagt agtaaatgac tagcataact ttttgaaatt acccaatgaa
    15361 atcctattgg gctttttcga ctggaggtag aaatcatcaa aatgtacaaa ggacatcgca
    15421 tacgcgcagg agatcaacac ttgatttatc actttgttct tggctggcta agtgccttat
    15481 tcatcggttg gatgggcgtc ttttattttc cagagcttag acaatttggt ctttctaagg
    15541 tatcattttc cactattgaa atcgcttggt ccatgaaaga tttagtatgt ctgcttggaa
    15601 gtctcgctct ttcaggaagt atgatgttgc tttatattca tttttttcct gatcattggc
    15661 gaagtttgtg gaatcgacaa aagctagcca gaatgattct agaaaaccat tggtacgaag
    15721 tgaagcaaac tcaaagtgat ggctttttca aagatttgaa taggagtcga accaaagaga
    15781 ctatcagtta cttccccaaa gtttattatc gaatgaaaga tggcttactg tctattcgcg
    15841 ttcaaatttc actgggaaaa tatcaagatc agctattgaa gttggaaaag aagttagaaa
    15901 gcggactgta ttgtgagtta gtagaaaagg aactcaaaga ctcctatgtg gaatacacct
    15961 tgttatacga tatgattgcc aatcgaattg ggatagaaga agtagtggca gaaaatggga
    16021 cgttgcgatt gatgaaaaat caagtatggg cgtatgattc cttgcctcat atgttaatcg
    16081 ctggtggcac aggtggtggg aagacctatt tcttactcac cattattcaa gcactattga
    16141 agtcagatgc agaattgttt atcctcgatc ccaaaaatgc ggacctcgcc gatttaggta
    16201 cggtaatgcc tcatgtctat tctcaaaaag aagaaatttc taaatgtgtg gaagattttt
    16261 acgaacgcat gatggctcgt agtaggtcaa tgaaagaaat gcccaactac aaaacaggag
    16321 agaattatgc gtatctcgga cttccgccca actttttaat ctttgatgaa tacgtggctt
    16381 atatgggtgc gaatcgtttt cctacaagca tcgaatagat gtgaaatgga agcctattga
    16441 gattatcaat agtgacaact aatgttttga gagatggaat gaaagccttc aagttgagct
    16501 gaaacatccc cgctaatact cctacatgct ctaatcaatg aagtagattg gttttggtat
    16561 gaagctaggt gaagtcgtct gaaatctgcc taagtgcttg agcataaggc tgactatagg
    16621 gcgggcggct gaaaaagata actatggtaa gaatgtctga aaatgactga cgaatctgcg
    16681 aatgtacggg tctaaaaggc tgatcttatt gaaagatagg aacatacgga cgtatggtga
    16741 gataccgaca agtaaggttc catgatatga aaatcgggat agctaacgaa gaagctataa
    16801 tttcacaggc tcatagtaga tacctaaggt tatacatgat agctaaaaac attggaacga
    16861 tgtaagcaga aaactatcaa ttaaatgact acttctagat aggtgcatat aagtaataac
    16921 gaaattgctt tgtttctgtg aaagtaaggg cacagtaccg atgaagcgtc taacaaatgt
    16981 ggagggatag ccctaagtct atttaataac aatgaatgtt gaaacagatg aagttcaagg
    17041 atctggtaag aacgtgggaa aatccgttat ggaggtgcca cgcttgaaca caaaaatacg
    17101 ttactgggaa tattatgatc tacaagaaac attcgatcag ctatttactc aaagtagaaa
    17161 cgggaaaaag ttttatcaat tatatgagtt aatcatttct gaaaataata ttcttttagc
    17221 ataccgtact atcaaggcaa acaaggggtc ttcgacacca ggaacggatt ccttcacaat
    17281 tgataactat aaggaaatga accaagcaga gtttatccat cttattctca gtcatttaga
    17341 aaattacaaa ccaaaatcca taaagcgagt aatgatacct aaacccaatg gtgagaaacg
    17401 cccattagga attccatgca tgattgatcg aatgatccaa cagatgttca agcagatact
    17461 ggagccaata tgtgaagcta agttttatga acatagctac ggtttcagac cattgagaag
    17521 tgcaaagcat gctctaggtc gcattatgta tctcataaac atcagtaaaa tgcactatgc
    17581 agtagacatt gatatcaaag gtttctttga taatgtaaac caccgtttac tgataaaaca
    17641 attatggaat ataggaattt gtgacaaaca agtcttagct attctttcaa aatctctgaa
    17701 atcacccatt caaggagaag gtatcccgag caaaggaacg atccaaggag gtatcatttc
    17761 tccactatta tctaatgttg ttctaaacga cttagaccat tgggtctcaa agcagtggca
    17821 tacctttgaa acaaagtatc cctatactaa aggttacaat aaatttcgtg ctctaagaga
    17881 tacaaatcta aagcaaggct atattgtcag gtacgcagat gactttaaaa tcatgactaa
    17941 tgattatccg acagcattaa aatggttcca cgctgtcaag ctttacctaa aagacagact
    18001 taaattagat atttccaatg agaagtctaa aatcgtcaat ttgcgtaaat gtaagtcgga
    18061 atttttagga ttcgctattt gcgtgaaaca aaaagggaaa aaatgggttt gtaattcacg
    18121 tatttctaac aaaaaaaagg atcagattaa agaagagatt aaacaaagaa tcaaagatat
    18181 tcaaaagagt cctacagcac aaaatgctct cctgtttaat gctctcgtgc tcggtgttca
    18241 taattatttc aggtatgcca ctcatattaa tttagatttg aataggatga actacgttct
    18301 ttcattcact acttacaacc gattatcaaa ttgtagtaca agatgttacc ccaacaaagc
    18361 ttccccaact tacaaaaagt tttactcaac aacgatgaaa acttataaag tagctggagt
    18421 ctatttgtac cctctttgcg acgtatctac aaaaacaatt tacggattta atacgaagga
    18481 tacaccgttt actccgtttg gtcgtcaaag attggagcac aaaagcctac agtctcttgt
    18541 gttccaagaa ttaagaaaat tgatggaatc gaaaataccg aatagaacgg ttgagtattt
    18601 agatagtaga atatctcgtt actcaatgaa atcaggcaag tgtgagatta caaaacaatt
    18661 tttgccagca aaagccgttc actgtcatca ctatttgcca aaaagtcttg gtggagacga
    18721 caaattcgat aacttgagaa ttattcataa ggatatccat cttctgatcc atacaacaaa
    18781 taaaatgata atcgatcact acgtgcatga actgaaactg gtgccagagc aaatagcaaa
    18841 aatcaacctt tatcgaaaga tgtgtaatct gcaaaacatt caatagaaaa taaatagatg
    18901 gaacgccgta tgaggtgaaa gtctcacgta cggtgtggag cgggggaaaa gatggagatt
    18961 atatcaaatt cttacctatc gctataaatg ttaacgacga aagagagtgc ggtgattttg
    19021 aataagctca aacaaatcgt gatgttaggt cgtcaagctg gtttctttct gattttggct
    19081 tgtcaaagac cagatgcgaa atatttagga gatgggattc gcgatcaatt caactttcgc
    19141 gtggctttgg gtcgtatgag tgaactcgga tattccatga tgtttgggga ggtcgaaaaa
    19201 aacttcttta tgaagcacat caaaggtcga ggttatgtgg atacaggtgg cagtgtgatt
    19261 agtgagtttt atacgccact tgtaccaaaa gggtatgatt tcttagattc aattagtaat
    19321 ttagaaaaga tgaatgattg agtgatcttc aatactgact ttatacttca agtaacgtat
    19381 aatactttta tatagtagga agaaagggga taattaatat ggaaagtaat gattcttatt
    19441 tagagtatgc aaaagcaaat aaggataagt ttatttctta tattatcaaa gggaaatccc
    19501 ccaaagttgg acgagacgca gtttttatgg cagggagtcc tggggctgga aaatcagagg
    19561 ttgccattgg attagctgag aattatgata accatgtgat tattgatgcg gattactttc
    19621 gcacccagtt tcctgattat aatggaaaaa actctagtct ctttcaaaaa gcatcttctt
    19681 ggttggtaga gtaggcattt agatatgtct tagatcatgg ctattctttt attctggatg
    19741 caacttttgc aatattaagt gctgaaaaaa atatctcgcg ggcgttgaaa aaacattttc
    19801 gagtgacgat tttctacgtt tatcaaggcc ctaaaatcgc ttggaaattt acacaagaac
    19861 gtgaaattgc agagggacgt catgtgccga aaaaggcatt tattaacgct tttttcaaat
    19921 caagagagaa cattgcaaaa gtaaagagta aacatccaga tgtattgctt catatcataa
    19981 taaaagatta tacgaataat atttccgaag ttcattatgc tacggataat ctagaattat
    20041 ttttaccact agagtatagt aggaaagatt tggaggttca attacatgac tgagaaagaa
    20101 caagtaacga aaattgtaaa gaaatacaat aagagcattg cggatttatc ggaaaatgct
    20161 actgcaaaag agttcaaaac ggtgattaaa tatgtagccg atcaggccaa tgaaaaacaa
    20221 cggaaattag ttggattaaa taaaaaatag taggacaaat taataatgta tgagccaaga
    20281 gcaaaatgtt cttggttttt ttctttgcaa tgaatgaggt aatgtatgag atttttagat
    20341 ttattcgccg gtattggtgg ctttcgttta ggtatggaac aggcgagcca tcattgtatc
    20401 ggtttttgtg aaattgataa atttgctaga cgtagttata aagcaattca tgatacaagt
    20461 aaggaggtgg aaatgcatga catcacaagt gtatcagatg agtttattca atccctcgga
    20521 ccagtggaca tcctttgcgg cggatttccg tgcgtgcgat gcgttcctaa ttgaaaagat
    20581 taggcactga tgtatttaag aacgcgaaag tgttcagttc agtagaactg atgatttaaa
    20641 tggtggaatg aaggagtaac gccctgaaac gcctaccctg aggttacgct gtgcagaatc
    20701 gtgggtaatc atgatgatgt gcaaagcgcg ttgaagtcgg cagagagtta cccaaacaaa
    20761 gagaaatgtt ctcaggtgtg gaaagtcctc cagagatgga ggatgtagcc tatatgccgg
    20821 gggtctataa actatctatg gttagtatgt aatggcaatt actagacgaa tgtccgtatg
    20881 tacgggtcta gagaacgcag ataatagaaa tgttatcacc actacatgtg ggttgtgtga
    20941 ggtctagtaa aattgcacgg tatgaaaaac cttgtaacgt tataggcgtt accaagcaca
    21001 caggctcaga gggcaaacct aaggataaaa ttgaacagat tgaatcatcg gaacgcagta
    21061 aggtcaggac gtggagtgat tacacacgaa gaagcggtaa tagggaaaac gattttgtat
    21121 aacctatttt tatctgaagg aaagcggagc cacagtaccg atgaagtcat ggaaacatga
    21181 tggagggata ggctctagtc aatgagagac gataaccatt caacacacga attttcaaag
    21241 gttcgagtac gactaagaaa ggcaaagtat tctataaaaa ggagaactgc cgactttgac
    21301 gactgagaaa ataatgaaaa agcagaaact aagaaacgct gaatattatg actttcagac
    21361 tattcaggat cagctttata gtcaaagcaa gcatggaaaa atattcaagc acttgatgga
    21421 tatcatttca tccgaccaga atataaaact tgcttatcga aacatcaaaa agaatagtgg
    21481 aagtcacact ccaggcgtag atggaaaaaa tatcgagaac cttgccaagt ggcaagacga
    21541 tgcattaatc aagcatgtga aacggaagtt tcaatggtac gaaccacagg caatacgcag
    21601 agttcaaata ccaaaatcaa gtgactctac caaaacaaga ccacttggaa tacctaccat
    21661 tatggataga cttatccaac agtgcattct tcaagttcta gaaccaatat gtgaagcgaa
    21721 attctatgac aaaagtaatg gatttcgtcc aaaccgtagt tgcgagcacg cactcgcgca
    21781 agctgagaaa aatatgcagt tatcaaaatt acactttgtc gtggacatcg atatcaaagg
    21841 attctttgac aatgttaatc atggaaaact gataaagcag ttatggacat tgggcatcag
    21901 agacaaaaaa ttgatatgta ttctttcagc gatgctaaaa gcagaaatcg ctggtgttgg
    21961 ctttccagaa aaagggtcac cacaaggctc aattatttca ccattattat caaacgttgt
    22021 tttaaacgag ctagactggt ggatttcaag tcaatgggaa acaattccga caaaaaagga
    22081 atacaagcaa tgcgatggtc attcaagtgg gcggctacaa gcgctcaaaa aaactaatct
    22141 aaaggaatgt cgattagtac gctatgcaga tgattttaag attttttgtc gaacaagaag
    22201 tgacgctgaa aaaatctttg tagctactga aaaatggcta aaagagaggt taggtttaaa
    22261 tatcagccct gaaaaatcca gaatagtgaa tctcaaaaag cattattcgg aatttctagg
    22321 cttcaggttg aaagtggtta gaaaagggaa atatcctaac gggaatcccc gttttgtcat
    22381 aaggtcacat atctcaaaaa aagcattgaa aaatatacat ctcagtgcga aaaaacgaat
    22441 tagtaatctg cagaatttat ccgatgacag agaatgttat aaatcagttc aaaattataa
    22501 catctttgtt ttaggaatac acaattacta ttccaaagct acacatgcta gtctagattt
    22561 tgcaaaaatt gcctttccta tcagaaagag cctaaaagga aaactacaag gaaacttctc
    22621 gaaagaaaaa ggaatatgca gcagcttaat tgaaaacaga tacggaaaaa gcagacaatt
    22681 agcttatgtc tatggattcg cttttatccc cattggctat gttcaacatc gggccccatt
    22741 agataaaaag cgagaaatca atcagtacac ggccgaaggt agagagttga ttcataaaca
    22801 attaggaagc tcaatcaatc cagacttact gagttaccta atggaaaacc caatcaaagg
    22861 taaaagtatc gaatataacg ataatcgatt atcacttttc tgtgcgcaaa aaggaagatg
    22921 tgcgatcaca ggtgatgacc ttaccattgg gaatatgcac tgtcaccaca aactatcttt
    22981 gaagttaggt ggaacagatg aatacaaaaa cttagctttt gtaacggttg aaattcatag
    23041 actactacat gcgacaaatc tgaaaataat cattgagtta gtgcagaaac tgaatttatc
    23101 gagaacgcaa cttgagaaag taaacaagtt acgaaagaaa attgctcttc caatcattga
    23161 ataattttca aagttgaaat cgtgtatatg aatgtaaaag aatttcgttg atggaaagcc
    23221 gtgtgaggtg aaagtctcat gcacggtttg aagcggggaa aaatctagag ataatttcaa
    23281 aggattacct atcgcaatca agctttttca attgcgggaa agcggcaagg attttccgat
    23341 actcgaggta ctttattctt tgaaatcgct cggttcgcca ctcttctccg acctaagctt
    23401 ttattccttg agaacgtccg aggattgctc aatcacgaag gaggggctac gttcgagacg
    23461 atcctccgaa cgctggatgg attggggtat gacgtggagt ggtaggtgct taactcaaag
    23521 gcctacattc ccccaaagcc gggagcggat attccttatc ggacattctc gagacgcatg
    23581 taccgaacaa gtatttccta tcattggacc gtcttcaaca tctgatcaaa acatccgaaa
    23641 tttggtaaat atcaatcctt ccaatcgagg aatgggtgga caagtctatg gttcagatgg
    23701 cgtagcgcca accttaacag gtgatgaagg aatcaaaatc gcactgccag caagggatgg
    23761 aatctctgta gcaggactat taccgggaaa gtttgaacaa ggtaatcgag tttatgaagt
    23821 tactggaacc gcccccacct tgtccacgaa acaaggtggt acaaaaatca tgattcgaaa
    23881 aaatgaaaca gaatatcaag aggtgaagcc aggagacagt gtgaacctga cttttcctaa
    23941 ttccacaagt cgccgaggtc gtctgggaaa acagagtgtt cataccttac taacaggaga
    24001 ccaacaagcg attgtcatgg atcagtatca aattcggaag ctaacaccta gagagtgttg
    24061 gcgacttcag ggctttcccg attgggcttt tgatcgagct tctcaagtca attcagatag
    24121 tcagttgtat aagcaagccg gaaactctgt aacagttccg gtcatttttg atattgccag
    24181 aagattaaag gaggtacaaa agtgtgattt atgatgagtt ggttggagaa atttattggg
    24241 tgattggaaa gattcagtca gacccagaat tagaagaaca attgcgacgg ttaaactttg
    24301 atattcgcaa gaatggtgtc aaagtcgctg gcgatccata tttaatgaat gaggagacgg
    24361 atgctcgaat tgaaataaac caagtaattg cagaatttga gcggattgcg gaccaagcaa
    24421 aagaaccgga tattcgtcaa tacttgttag aaatgaaagc agagttggaa gtaaatggta
    24481 ttacagatga gtaacctaaa ccaacacaac tgactgttag gcgctgaccg cggaggattc
    24541 gcgaagcaga aatcctccgt ggtgctgtgc ctgttcatgg acggcgttag ccggccatga
    24601 tgtcttaccc cccgtatcta acaggggggt acaaaaacac aaaaaacaag caagcagcga
    24661 ttaagaatgg ttgtcatgac gaggatagtt agctgtttga acaggtgtta actcattttg
    24721 aaaagttaac accttatttg gaggtgaaaa cttggtacaa cagaacttag attatcgttt
    24781 actaaaagat cggcgcaatc aatatggtgt ttctcaaaat aaattggcta ctgcttgtgg
    24841 attgagtcgc ccctatttga atcaaatcga aaatggtggc gtaactacat ctacaaaaac
    24901 tatgagaaaa atttttgacc aactggaaag tttcaatccc gatttgcctt tgacgttact
    24961 gtttgattat gtaaggattc gttttccgac aacggatgtt caaaaaattg ttcaagagat
    25021 tttgcatttg aaatttgact atatgcttca tgaagactat gccttttatt cgtaccaaga
    25081 acaatacatc atgggtgata ttgtggtgat gctttctcat gaggaagaga aaggcgttct
    25141 tttagaatta aaaggtcgtg gttgtcggca gtttgaaact tttttgctcg ctcaaaagcg
    25201 tagctggtac gactttttcg atgattgctt aaaagctgga ggcgtcatga aacgcttgga
    25261 tttggcaatc aatgatcgag ttggcttatt ggatattcct gagttgacga aaaaatgtca
    25321 gaaggaagaa tgtatctcct tattccggac ttttaagagt taccgctcgg gtgaactttt
    25381 gaaagctgat gaaaaggatg gaatgggaaa tactttgtat atcggaagcc ttaagagtga
    25441 ggtttatttt tgtttatacg aaaaagacta tgaacaatat atcaaattgg gaattccgtt
    25501 agacaagagc gaaacgaaga atcgctttga aattcgattg aaaaatgacc gtgcctacca
    25561 tgcaatacaa gacttgttaa aaggtcgaag tattgagggt accacatttt ccattatcaa
    25621 ccgttactta cggttcacgg ataaagttga agggaaacgg cgaacaaact ggccgctaaa
    25681 tgaacgatgg ggtcgcttta tcgggcgaaa tcgcaaggaa attcaactga cttctgaccc
    25741 caaaccttat actatcgagc gaacactgaa ctggctaggt cgacaggtag cacctacgtg
    25801 gaagatggct aaggagttag atcggttaaa tcagacgact tatattcttg atatggtaca
    25861 gaatgctcag ctatcggatc ggcataaaaa gattttggaa caacaaagta tggcaataga
    25921 aaacttgatt atatgaaaag aggaagcagt atgcttggtg ttaccgtgat gtgcttaatt
    25981 catacaagtg cggctgcaga tcgagtaatg gaaaggaaag tgataaaatg aatttcggac
    26041 aaaattt
//
LOCUS       DAPBBR010000038        25699 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPBBR010000038 DAPBBR010000000
VERSION     DAPBBR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.038"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            131..3658
                     /locus_tag="RD488_001788"
     CDS             131..3658
                     /locus_tag="RD488_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDT7657860.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="RD488_001789"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="RD488_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDT7657861.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="RD488_001790"
     CDS             7446..7787
                     /locus_tag="RD488_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7657862.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="RD488_001791"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="RD488_001791"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDT7657863.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /locus_tag="RD488_001792"
     CDS             9144..11564
                     /locus_tag="RD488_001792"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDT7657864.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="RD488_001793"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="RD488_001793"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDT7657865.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="RD488_001794"
     CDS             12998..13735
                     /locus_tag="RD488_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7657866.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="RD488_001795"
     CDS             13749..14564
                     /locus_tag="RD488_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7657867.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="RD488_001796"
     CDS             14577..15224
                     /locus_tag="RD488_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7657868.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="RD488_001797"
     CDS             15240..15896
                     /locus_tag="RD488_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7657869.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="RD488_001798"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="RD488_001798"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDT7657870.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="RD488_001799"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="RD488_001799"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDT7657871.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="RD488_001800"
     CDS             18238..18756
                     /locus_tag="RD488_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7657872.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /locus_tag="RD488_001801"
     CDS             18863..19363
                     /locus_tag="RD488_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7657873.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="RD488_001802"
     CDS             complement(19643..20563)
                     /locus_tag="RD488_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDT7657874.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20728..21741
                     /locus_tag="RD488_001803"
     CDS             20728..21741
                     /locus_tag="RD488_001803"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDT7657875.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="RD488_001804"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="RD488_001804"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDT7657876.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22826..23266
                     /gene="fabZ"
                     /locus_tag="RD488_001805"
     CDS             22826..23266
                     /gene="fabZ"
                     /locus_tag="RD488_001805"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7657877.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23381..24142)
                     /locus_tag="RD488_001806"
     CDS             complement(23381..24142)
                     /locus_tag="RD488_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7657878.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24331..25425
                     /locus_tag="RD488_001807"
     CDS             24331..25425
                     /locus_tag="RD488_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7657879.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25511..>25699)
                     /locus_tag="RD488_001808"
     CDS             complement(25511..>25699)
                     /locus_tag="RD488_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7657880.1"
                     /translation="NSNGILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
BASE COUNT         8508 a         4455 c         5417 g         7319 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgtg cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ctttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aaaatttgat agtcgtaaaa aaatagagaa taatagctaa aataacttct
    22681 tgatttctta attattagtc aaaatgtttt gattgtcaaa ctattttttc ttaaattaaa
    22741 aaaagattgc taaatattta ggaatatgat actttgatag tcaaagtaat gaaaatggca
    22801 attgcctgaa agaaggagtt taattatgtc ttacgtatta tctgctactg aagtaatgga
    22861 attgattcct aatcgttatc ctatttgtta tattgattat gtagatactt tagaaccagg
    22921 aaaaaagatc gttgcgacaa aaaatgtaac aatcaatgaa gattttttcc aaggtcactt
    22981 tcctgacaat ccagtgatgc cgggtgcgtt gattctagaa acactggcac aagcaggttc
    23041 gatacttatc ctaaaatcag aagagtttct aggaaaaaga gcttatatcg gtgggatcaa
    23101 taaggccaaa ttccgtcaaa aagttgttcc aggagatgtg ctgaaatgtc attttgaaat
    23161 caccaaaatg aagggatcag tcggtacagc gttatctgca gcatatgtag atgataaaaa
    23221 agtctgtgag tgcgagttca cgttcatcgt caaccaaaat gcttgactat aaaacctgat
    23281 atagcaaaac aaaaggaagc ttacttgctt tttatgtaaa aagaagacgc ctgaatccta
    23341 gcatacgttg tcatctatgc aggattcaga cgttattttt ttatttttgt tttgcttctt
    23401 gcagtatatt gattttatcg atttttactt cttcttttgg tttgtctgaa ctatctgttt
    23461 cgatatttgc aatagcatcc acgacatcca ttccttcaat cacttggccg aagacagtat
    23521 aatggccatc tagtgaagga taaccgccgt ttttataagc gtcgatgatt gcttgaggat
    23581 agtcgtcttt taaaagacca tcatgcatat catctgtatt ttgaacgata aagaactggc
    23641 tgccgttact gttaggatct tgtgagcgag ccatagataa cgcacctctt atattataaa
    23701 ggtggttgtt gatctctgtt tcaaatcctt ctccccaaat gctttcccct ccagtgccat
    23761 cgcctttagg atcgccacct tggatcatga aatctttgat gacgcgatgg aaagtcagtc
    23821 cgttgtagta accgtctttt gcatgtgtca taaagttttc aaccgctttt ggtgcgtgtt
    23881 cgggaaataa tttgattttg attgtgcctt tattcgtcac catttcgacc agatcttcat
    23941 tttcggcgac atctttcgtc aattgtggta attccaatgc gttcaaatcg acgctactgg
    24001 cagtcgtgct ttccgcagta gatgtacttt ttgaactttc tgtagacgaa ctagaagaag
    24061 tcgtgttgtt tgcagaacaa ccagcagcaa acagcaatgc tgctgctaaa ctaatactta
    24121 aaataacttt atttttcttc ataactgttc ctttccaatt tactattttg ttatctttaa
    24181 tgataacaaa atagagggaa aatacctact taaattattg gaatttatca tttattttaa
    24241 aagaaaaaga aaaggtgtag accatttact ttgtgtttgc tataatgtaa gtggatacaa
    24301 aaacgaaaag atgcaggagg aaatggtaat atgggaaaat taggaatctc gatttatcca
    24361 gaacggtcaa catttgaaaa ggacaaagcg tacttggatt tagctcataa gtatgggtat
    24421 aaacgggttt ttaccagttt gctgcagatc aatgatgata aagaaaaagt tctttcagaa
    24481 tttaaagaag tagttgatta cgcgaatagc ctaggcatgg aagtaatggt tgatatcaat
    24541 ccagcgttat ttgaacagtt ggagatttct tacgatgact tatctttttt ccataagatg
    24601 ggtgcctacg gggtccgctt agatatcgga ttcacaggag cagaagaagc aaaaatgacg
    24661 cgcaatcctt ttggtatcaa aatcgagatc aatatgagtt cgggcacgaa ttacgttgac
    24721 aacatcatga gttattcgcc aaacacggat aatttattag gttctcataa tttttatcct
    24781 catcgatact ctggtttagg atacgaacac tttgtttttt gttcagaaaa attcagaaaa
    24841 tataatttga atacgatggc attcgtcaat tcgcaatctg ctgagtttgg cccttggcct
    24901 acgcaagatg gcttgtgcac gctggaagac caccgagatc ttgaaattgc gacacaagtg
    24961 aagcatttaa tccttacagg attgattgat gatatttcta ttggaaatgc gtacgcaagt
    25021 gaagaagaat tgaaagaaat ggcagaagca tttaacgcgg attatccaac attgaaagta
    25081 gatacggaag aaggtattac agaaaacgaa cgaatctgct tgtttgataa ccttcatagt
    25141 tatcgagggg atcgctcaga atatatcctt cgttcaacga tgactcgtgt atactacaaa
    25201 gataaagatt tcccgcctca taatacgcga gatatgcatc atggggatgt actgattgac
    25261 aatgaagggt acggtcaata caaaggagaa acacaaatcg ccttgaagga tatgaaaaac
    25321 gacggacgtg tcaatgttgt aggaagaatc tccgatgacg aattattcct ccttgacttt
    25381 ttgaaaccat ggtcaagctt taaattaatt gaaaataaaa aatagataat tagttattgc
    25441 agaaataatc cgctagaaat agccagttat ttctgctttt ttattttgtt tttttatagg
    25501 ttatgatttg tcaaattaag ctagaataaa atgcttcttg tacatagctc aaaaatattt
    25561 cgattggtgt tctgtaattc aatgattttc ttggaatatg attacgttga ttgctgacac
    25621 tggaaataaa tgtctgattc acttttctaa aatccattga tttcggcagt ccattacgac
    25681 gcagaatccc gttagaatt
//
LOCUS       DAPBBR010000039        24821 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPBBR010000039 DAPBBR010000000
VERSION     DAPBBR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.039"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            202..1008
                     /locus_tag="RD488_001809"
     CDS             202..1008
                     /locus_tag="RD488_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7657881.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1020..2240
                     /locus_tag="RD488_001810"
     CDS             1020..2240
                     /locus_tag="RD488_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657882.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2230..3816
                     /locus_tag="RD488_001811"
     CDS             2230..3816
                     /locus_tag="RD488_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7657883.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3855..5993
                     /locus_tag="RD488_001812"
     CDS             3855..5993
                     /locus_tag="RD488_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7657884.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(6361..7344)
                     /locus_tag="RD488_001813"
     CDS             complement(6361..7344)
                     /locus_tag="RD488_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDT7657885.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            7722..9113
                     /locus_tag="RD488_001814"
     CDS             7722..9113
                     /locus_tag="RD488_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7657886.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            9129..10169
                     /locus_tag="RD488_001815"
     CDS             9129..10169
                     /locus_tag="RD488_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7657887.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            10188..11273
                     /locus_tag="RD488_001816"
     CDS             10188..11273
                     /locus_tag="RD488_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HDT7657888.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            11306..12268
                     /locus_tag="RD488_001817"
     CDS             11306..12268
                     /locus_tag="RD488_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7657889.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            12261..13688
                     /locus_tag="RD488_001818"
     CDS             12261..13688
                     /locus_tag="RD488_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDT7657890.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            13690..14760
                     /locus_tag="RD488_001819"
     CDS             13690..14760
                     /locus_tag="RD488_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657891.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            14747..16168
                     /locus_tag="RD488_001820"
     CDS             14747..16168
                     /locus_tag="RD488_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDT7657892.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            16181..17188
                     /locus_tag="RD488_001821"
     CDS             16181..17188
                     /locus_tag="RD488_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7657893.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            17200..18204
                     /gene="neuB"
                     /locus_tag="RD488_001822"
     CDS             17200..18204
                     /gene="neuB"
                     /locus_tag="RD488_001822"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HDT7657894.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            18201..19349
                     /gene="neuC"
                     /locus_tag="RD488_001823"
     CDS             18201..19349
                     /gene="neuC"
                     /locus_tag="RD488_001823"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HDT7657895.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            19322..19999
                     /locus_tag="RD488_001824"
     CDS             19322..19999
                     /locus_tag="RD488_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7657896.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            19989..21131
                     /locus_tag="RD488_001825"
     CDS             19989..21131
                     /locus_tag="RD488_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDT7657897.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            21144..22121
                     /locus_tag="RD488_001826"
     CDS             21144..22121
                     /locus_tag="RD488_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7657898.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            22121..23029
                     /locus_tag="RD488_001827"
     CDS             22121..23029
                     /locus_tag="RD488_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HDT7657899.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            23030..23782
                     /locus_tag="RD488_001828"
     CDS             23030..23782
                     /locus_tag="RD488_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HDT7657900.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            23787..24734
                     /locus_tag="RD488_001829"
     CDS             23787..24734
                     /locus_tag="RD488_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDT7657901.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         8726 a         3470 c         4637 g         7988 t
ORIGIN      
        1 aaatacgaga gaggctgtga caaccgtcgc agcctttttt ggtttattgc aattgtctag
       61 catcttctgt aaaatagaaa cgttagagaa aatcttgtat catagaaaat taagaaagaa
      121 ataagaacgc agctcggtac caaaaatatg gtaaaatggc acttgactgt aattcactga
      181 aaatcgcttg gaggaacaca aatgtttaaa gatttgtatt tatttatgaa ggacatttat
      241 cagaacagaa aattattgct acagttttcg atcaatgact tcaaatcaag atatgcagga
      301 tcgtttttag gaatcttatg ggcgtttatc aatccgctat ttactgtatt gatttattgg
      361 ctggtatttg gtgttggact gaaagcacaa atgatcgatg caaaataccc atttatcgta
      421 tatttagtta ccgggatgat tccctggttc ttcttctcag atgcatttgc atcaactacg
      481 gttgtttttc gggaatatac ttatttagta aagaaagtcg tattcaatat tcgtatcttg
      541 cccacgacga aaatcctatc caatctgtac acccatttat tcttcattct gattggcata
      601 gctgtcgcgc ttataaatgg tatatatcct tcagcaatgt ctttacagct gatttattat
      661 ttattttgca tgtgtgcttt cttgacagga ttgacttggc tgacggcatc gatccaacca
      721 tttttacctg atatcatgca attaattacg atcgtgctgc agttgatcat gtggacatta
      781 ccgatattat ggagccctaa tcagtttgat tcaggtcttg taagcatatt gaaattaaat
      841 ccgctgtact atgttgttca aggttatcgt gagtcatttt taagtgaagc ttggttctgg
      901 gagcatggaa catatacttt gtatttctgg gttttcacgt tagtaatgtt cgtaatcggc
      961 tctgcagtgt tccgtagatt gaaaccacat ttttcagatg tgctgtaagg agaatagcta
     1021 tgacagaata tgcaattaga ctaaaagata tcacaaaatc ttataatatg tacgcaaaac
     1081 cttcggatcg atttcgtgaa gccctcaatc cttttaagaa atcctatcat gatgtatttt
     1141 atgcgttgaa aaacgtgaat gtagaaataa aaaaaggtga gatgatcggt ttcgtgggag
     1201 aaaacggatc gggaaaatct acaatgttga aaatcattac gggagtactg acaccaacat
     1261 ccggcacgat ggaaatcgaa ggaaaaatct cagctttgct agaactagga tcaggattca
     1321 atcctgagta ttctggctat gaaaatatct atttaaatgg aatggttcta ggattttcaa
     1381 gagaagaagt cgatgaaatg gtcgatgata tcattgaatt tgctgacatc ggagaccata
     1441 tttatcaacc tgtaaaaact tattcaagcg ggatgttcgt tcgtctagct tttgctgtag
     1501 caatcaatgt gaatcccgat attttgattg tggatgaagc attggcagta ggcgatcttg
     1561 aatttcaact aaaatgtatg gaaaaattta cagaaatcaa gaactcggga aagacgattt
     1621 tattcgtttc tcatgatatc agttcgattc gtcgtttttg tgatcgttcc tattggttga
     1681 aaaacggaga agtcgtcgaa tatggcgata cgatggaagt aacgacgaat tatgaaaact
     1741 ttttaaagaa aaaatcagtt aaaacagtgg atcggaataa aaaccaagta gaacggttcg
     1801 ccgctccaga tatcgtcgac gtgacgaaag cggaattgtt ggataaagac aaaaatccgg
     1861 tggatatgct ggaacaagga gaaaaactat acgttaaagt aacttatgaa gtaaaagatg
     1921 atacaatcaa aaatccggtt ttaggaattg cgctacgaac agtcgacaat ttttatgtat
     1981 gcggacttaa tactctacta gatggtatca agattccttg gaaaaaagga gagaatatct
     2041 tttatctgga gtatgaaaag ttaggtttgt tagctggtga atattatttt gacgttgcgg
     2101 tctttgaaga aaatgcaacg gttcctttgg tatataagac aaagtacatg aacttgtttg
     2161 tcagcggttc ttatatcgga gaaggcatcg tggtcttaga ccataaatgg gaagaaggga
     2221 ctcatagcaa tgaaatatga ttttgaaatg gacctagatg aacaaagcag tgtgggaaaa
     2281 attgccgcac agatcaaacc aggaagtaaa gttttagagt ttggtcccgg aaacggccga
     2341 ttaacgaaac atttaatcgg agcaaaacaa tgtgaagtga gcattgttga gttagataag
     2401 gaattgttcg attttgtcag cgaatttgct caagatggat tttatggtga tatcgaaagt
     2461 tttgagtggg caaactatta tgctggacag acatttgatt acgtcttgtt tgcggatgtt
     2521 ttagaacatt tggtagatcc tggaaaaaca ttgaagaaag tcagagaatt tttgaatgaa
     2581 gaaggagaga tcctgattac attccctaac ttggcgcata attctgtcat gatcgatttg
     2641 ttcaataacc aattgccgtg ggcttcttat ggtctcctag atgaaaccca taattctttt
     2701 tatactcatg atggcttcca aaaagttttt gaaaaagcgg gattattcat taatattgaa
     2761 gattatttgt acttagctgt aggtgataca gaattaaaat caacttatga agaattgccg
     2821 gaagctgtac gctatgattt caaaatgcga ccatttggtg aagtctacca atactttttc
     2881 tcattgatga aacatccagt agcacaaagt tccattgcag agccacaaaa ttctaattat
     2941 gtaaaagtgt tagaagtaac ccagcaaacg aaacaagatg aaacaatcca acaaatacca
     3001 ttcaataatt tcacagggga aaatgagaca ctaagtttcc ccgtatcaga aacaacagaa
     3061 agaatggtgt ttcgcttcgc gcaacaacct agctttatcg aattcagcgc agaagctgcc
     3121 ggagaaaaac taacatttat cgattcgaat gctgtagtca aaacagtaaa tgattgttat
     3181 ttgtttgatg ggaaagaatt accagagttc gttctaacgg atatttctgg gaaagaagtg
     3241 actatccatt gtcactatcg ctttatcggg gaattgacac caacaatgaa agaattgttg
     3301 gaaacgattc gtcccatggc tgaagtcaca aagcagcttt ctgagaaaaa tgacgaatta
     3361 gaaagagaaa atcatcatct tcttgaggaa aatacaagac tagaccatac gttaaaaaca
     3421 accacaaatc gctattgcac attgttggaa agtgatgaat ggacaataaa acatagacta
     3481 ggacgacgta agaaagaaac ttcgaaaaaa atccaagaaa aagaactttc tatatgtatt
     3541 gacgagaaaa tctgggatgc agaaacaaaa atattaaaaa tcatcggatg gggaatcgct
     3601 aattcggatc gccagccctt gtcctataag ttatcagctg accaatcgcc atttttcgaa
     3661 gcaattcctg tttcacgaga agaagtcaat caagcagaac agctcgcaaa aggaacagaa
     3721 gcgggatttg agttacgaat cctttgcgag caagaacgtt cattcttagt ggaagcagta
     3781 gctcaaaatg gccaatcatg gatcattgaa atgtaaataa tgattaactt ataaagataa
     3841 ggagtaaacg aatcgtgcaa aaaaaagaaa ttgccgtatt tatcgatcaa atcactcgtg
     3901 aacgggccac tggcgatttg cttattgtgg gctgggcaat tgatgaagtg accaaagaaa
     3961 tccctacgat aaaggtagaa aaagaaaatg tgattgctga agcaacacat gtcgtaagat
     4021 tggatatcaa tcatttatat aatcttgatg ttaagaccca aagcggtttc aaggtacgtt
     4081 tatcagggaa aatgagagga aaagccatct tagacttcca aacagcgaga catcaaaatg
     4141 gcatagctgt gaaattaaac ggtaaatacc cttatgatga cggcattgaa tcttcatggg
     4201 aaagaaaaaa aagattactg aaaaaaggga taaattatgc aaggactcat ggcgtaaaaa
     4261 aagcgatccg tcgggtcaaa ttggaattga agccaggatc gatcgactat gcagagtgga
     4321 tcagtcgtca tgagaaacca gatttgaaag agcaaaggaa agaagcacaa ggatttgcgt
     4381 accgtccatt gatttccata cttatgcctg tctataacgt tgaaatcaaa tggctcgaaa
     4441 aatgcattga ttcggtactg gatcaaacgt atgatcattg ggaactatgt atcagtgatg
     4501 atgcttctac tgatccagct atccgaaagt gtctggaatc ctatcaagca aaagatgata
     4561 gaatcaaagt cgttttccga aaagaaaatg gacacatcag tctggcaact aattctgcat
     4621 tggaaatagc agaaggagaa tttatagcac tcttagataa tgatgatgaa ttaccgccat
     4681 ttgcattata tgaagtggca aaagtgctaa acgtacatcc agaactggat gtgatctaca
     4741 gtgacgaaga taaaatcgat gcagatggca atcgctttga tccgcatttc aaagcagact
     4801 ggtcgcctga tacattgatg ggaaataatt atatctctca cttaggcgta tatcgaacaa
     4861 gcattgttaa agaacttggc ggtttccgta aaggctatga aggttctcaa gattatgatt
     4921 tggtccttcg tgtgacagaa caaatccctg cagatcatat ttaccacatt gaccgagtct
     4981 tgtatcattg gcggacgatc ccaggatcaa ctgcaagtaa tggcgaagcc aaaagttata
     5041 tctatgattc cggagtgaaa gcattgacag atgccctgtc tagaagaaac atcaaaggaa
     5101 gcgtacgtcc tggcagaatt tctggatttt atgagattgc ttatgacgtc ttgcaagagg
     5161 atttggtcag tgtgatcatt ccaacgaaga atggctatga agatctaaaa acttgtgtgg
     5221 attcgatcat cgaaaaaacg tcttattcaa attatgaaat cattattgcg gataacggaa
     5281 gtacagatcc aaaaatgcaa gaattatttg cagaatacaa gcatcagctg aaagaccgct
     5341 ttatcgtaga attgattgac attccattca attattctcg aattaacaat ttagcagcag
     5401 aaaaagcaaa cggcaaatac tttttattct tgaataacga tacagaagtg attgagccag
     5461 attggatgac ggtgatggtt tcttatgcac agtttgatcg aatcggctgt gtaggagcaa
     5521 aactgtttta tccagatgat acaacgcagc atgcaggagt attattagga atcggtggtg
     5581 ttgcagggca tgcattgaat aactatgatc gaacacattg tggttatttc ggccgattgg
     5641 tcattgacgt caattactta gcagtcactg cagcttgtat gatggtcaag gcagctgact
     5701 tcaatgctgt taacgggttt gatgaaacat tagaagtagc attcaacgat gttgacttgt
     5761 gcttgaaagt ttatgaactg ggtcgttaca atgtctatgc acatcaagca gaattgtacc
     5821 atttcgaatc taaatcaaga ggttatgaag atactccaga aaaacaaaga cgttttgctg
     5881 gtgaaatcaa aaaaatgcaa gataaatggc cagcatatat tgcgcatgat ccattttaca
     5941 atgataattt aacaaaagaa ggaatcggcg acttttcgtt gagaccagat taaactataa
     6001 taaaaagctg ttatgttgtg attcgctcgc acataacggc tttttatagt tttttgtcaa
     6061 aaaaaggcag aaggtgccga ctcaaaaaaa taagtcgagg ttgggacaga agtgtttaac
     6121 tccgagaaat aagaagaaat tcacgaaaat tgcttttcaa atttttgtga atttcggctt
     6181 atttaagaag aagttgcttc tgctcccacc gtttattcgt ttttaaagaa tgagacaaaa
     6241 gtgtttctta cttttgtccc acgctcttat tcatgctcag agcgccaata gatacaaaat
     6301 catagccaaa gtttcacgaa ccctagctgt caaagaatcg atattttatt ttaatatagg
     6361 ctattttaaa ataaatggtt taaggtattc ctctacaaaa gccactctat caattatcat
     6421 gggtttaaaa taagaagtga tggagataac cagattgttc ttagcgtcaa tataaagaac
     6481 atttccacta ttaccaattg ctgaatatat ttcgttctca gaatctaata cccaccataa
     6541 atagccatat ctcatatttt gtaagtcttc taaagcactg gttctaggtt tgaacatctc
     6601 gtttatccac atgggtggta cgatttgttt tcctttatac atccctttat ttaggcataa
     6661 tacaccaatt tttgccagat cacttgccga taaacacaaa ccatatcctg ccgtcccgat
     6721 atttagtgga tcacaaaacc agacattggt tttaggagac ttatccattg taaactgctt
     6781 atgttcttca gctgtttcag cataataatt gacatggttt ggtatcccta taggatcaaa
     6841 tagatactta ttggcaaaat caacagttgt tagcttactt gtctgataca acaagccagt
     6901 taatatgtgt aaacagacag tttgatagtt gaattcgccg gttatacctt ttcttcctcc
     6961 caataaatct agtgatgttt ttgtccaatc ttcacttgaa cagacttttg tccatggatc
     7021 gcctttacat ttgtagggtg ctttcattgt tagcaagtgc ttgattgtaa tagcgtaaat
     7081 agttttctcc ccgcgtttca ctttatactc tggaaaataa tctaatactt tatcatcgat
     7141 acttttgatt aatccttgct ctaaagcaat gccaatcagc aaagatacaa tacttttcgt
     7201 tgctgacatg atatgacaag tatcgtcttt tttataacca ttccattcat ctgtataaac
     7261 ttctacccca tccttatatg cgacaatttg acatatattt ggttgtcgaa aaccaataaa
     7321 atcatgcaac tcttgtttat tcataagata ttacctcact ttcttctata agcataatgt
     7381 cattaaaaat cgatttcaat tttttcgatt cttcacgtaa tacaggtatt cttatggact
     7441 agacagcgct ttgggaagat ggattctctg aaaaatataa aggttcactt tatgagtgga
     7501 taaaaaaagc agcaaatact tcgacttctt taatttacca acattagtga aaatcgattc
     7561 atctggagat ttgtaattta gagtccttgt cttgattaga ggtgtataaa gctttttatt
     7621 agacattttt aaattccatt acaatttgct tataaactag gtttttaaag gtgactatgg
     7681 taagataata gagatattat tttgtgatta ggagtgtata tatgaataaa aatggagaat
     7741 ggagtgctgc acgacggata ttcattatat taatggatgt tattgtatac aatgcagcaa
     7801 tatatagtag tttcttactg aagtttcgtg gagagatccc attacgaaat ttagaaactt
     7861 tccaacactc agcaattatt atttcagtga tttttattgc gttgaacatt ttgttgggtg
     7921 catatgtttt ttataatcga atgatcagtg acatcgtgtt tgtcacagtc atcggtcagg
     7981 tattgatgac actagggatc atggtagtga cttttgcggg ccgctggttt gcttttccac
     8041 gtcttgttat cttactttca tttgttctcg gtacgctttt cttaagtatc tatcgtattc
     8101 tcgtatataa actttattta cgcgtaagtc gagataaaaa ggtcgtcatt attgggttag
     8161 aaaaggatgt cgcaccagca atccaaaatt ttggttcaaa gaaaaacaac aaacataaag
     8221 tcgaagcagt cattcttgat aactattatg caaacatcaa aaatatgatt aaagacatcg
     8281 atattgtcta tcttgcttct catatcgaag aaactgaaaa aatcaaaatc tatcaattag
     8341 ttactaaaaa tgaaaaaaaa ttgtttttga atacaacatt tgaaaacttg acattgatca
     8401 atccaaatat tatgaatttc gaagatgaaa gtattattga agcatctgga tttagaatcc
     8461 aacctgaata tgaactattc aaacgtttgt ttgatatcat cgtttcactt gttttattag
     8521 ttattgcttc accatttatg ttattcacag caattttagt caaagtgaca tcaccgggac
     8581 caatcatcta taaacaagtg cggatcacaa aaaatcaaaa ggaattttca atctataaat
     8641 tccgctcgat gaccgccaca gccgaagcaa aatctggacc agttttagct aagagcaatg
     8701 atgcacgagt aacgcctgta ggtaaattta ttcgagctgt ccgctttgat gaattaccac
     8761 aaatcttcaa tgtgctgaaa ggcgatatgt cgatcgtagg accacgtcct gaacgtcctt
     8821 tcttcgtcga tcagttcaat gcagaaaacc cttattacta cttacggcat aatgttcgtg
     8881 ctggtatcac tgggtatgca caagtctatg gaaaatatgt ctctgattac aacagtaaat
     8941 tacgttttga tttactttat atcaaaaaat attcattgat gcttgattta aagatcttgc
     9001 tgcaaaccat caagatccta tttgataaaa tgtcctctca aggacttgaa gaagacgaaa
     9061 atgtgatctc attggcagaa attgcttttc cgaatgaaaa aatctttcgc tagttgggag
     9121 gcgtaaaaat gaacaatccg aaattcagca taatcgtacc agtatacaat gcagaagcaa
     9181 ctattggtcg aacgattgat attctaaaag aattggatta tgaagagtac gaagtcgttt
     9241 tagtaaatga tggatcaaca gatcaaacac aggaaatcat tcaagaactg attgaaaatg
     9301 atgaacgttt tgaattgatt actacgacca atcaagggcc cggattagca agaaacgaag
     9361 gaataagaca gtcaaaagga gaatatctct tattcttcga tgcagatgac acgccagtaa
     9421 aaacgatctt gtcagattat gatcatttgc tagaaaagag tccaaaagcg gatcttgttg
     9481 ttagttcgtt tgtttttcgt acaatggacg agggaagaat cgtttccgaa aaagaaaact
     9541 tagttacaga atgtcactat ctaactcacg aagagtttat aaaagacatg tatcagttaa
     9601 tgaatgaaca gttgatgtat gttgtatgga acaaatgcta tcgtagcgat attctgaaaa
     9661 ataaccaaat tctatttaaa acttataata gttgtgagga tcgaatattt aacttacatt
     9721 attatgaata ctgtcatcaa gtgatcatga acccaaaagt agaatatatt tatgaatttg
     9781 aaggtgggaa ggggatcact aatcaatacc gacctaacaa gttcgaaaca tttaaagaat
     9841 tctattcatt agcaaatact gtaacagacg atattaataa agacggtatg gcggcgcttc
     9901 ttttaaaagg gacaacttca gttatttttt ctatttatag tacctctgca agaacttcaa
     9961 aagagaagaa agacgaagca aagcagatat tgagtgatcc agtgatccga gaagccaagc
    10021 aaattgctaa gacggattct tcagcaaaaa aaataacaaa gttgctttac aatatgccag
    10081 ctccactatt tttatctgct gtaaaagttg gaagcttcgt tgaagtgaaa atgccagggt
    10141 taatggctgc tttgaagcga gtatattagt taatggagga aaatataatg aaaagaattt
    10201 tgcattttca gggacgaatg ggtttaggtg gagcagagtc tttcatgatg aatttatatc
    10261 gtaaaattga tcgtacaaac tatcaatttg attttttgat ttatgaagat tatgcagatg
    10321 ttcaagacta tcattcagag attgaaagat taggaggccg tatttttgtt gtacctaatc
    10381 ctaagaaaaa tatttttaaa tatttaatag aagtgaataa gttactaaaa aaagaatctt
    10441 tttctatagt tcacaatcag gtttattttg gcgggggaat taatttatgg ttagccaaaa
    10501 agaatggaat cagacagaga attgctcata gccatgcaac tgaagatgga aaatctcaaa
    10561 atattgtaat gaatgtattg cgtaaatttt taaccaaatt gttgttacaa aatgcaacag
    10621 actaccttgc cgttagtcaa gaagctggtg aaagtctgtt tcaaaaccat ccctttgaga
    10681 tagttcataa tggtattgat ttagagcttt atagtaaaaa ttcagaagct aaggttaata
    10741 agagaaaaga attggatatc tcaatgagta cttttgttgt gggaaacatt ggacgattag
    10801 agaaacaaaa aaatcaatct tatttgttag agattttttt agaaatacta aaaatgaatt
    10861 ctgattctta cttgatttta gtaggtgaag ggtcacttag aaataaactg aaagccaaag
    10921 cagtagaatt ggatatagag aaaagagtaa aatttttagg agaaagaaac gatattcccg
    10981 agttattatc tgtgatggat gtttttgtaa tgccttctct ttatgaaggt ctgccaatgg
    11041 ttggattaga agcacaagca gcaaaattaa aattagtctt agcagatact atttccaaag
    11101 atacaaagtt aacaaataat gtggattttg tatcattaga tgaaacacca caagaatggg
    11161 caaaaaaagt aataaaagag ccgtatgcta ataaaataac acaagaacta aagagttatg
    11221 atgtttcgta cactactgaa caaatggaga gtatatatag tagagatcat taaaaatgtt
    11281 caagatattt taggagtgat tatttttgaa aatatgttat ttgatattgg catacaatga
    11341 tattggcaac ttaaagagat tggtcaatcg attgaacgaa aatgcagttt ttattattca
    11401 tatagataaa aaaactgata tagaaccatt tattgaagca tttaaatcat atgataatgt
    11461 tgaattttta tgtaataaaa accgtgttaa aatttattgg ggtggttttt ccattgtaca
    11521 agcagaaatc aatttagtaa agagagcatt acaaaatgag aaatatttaa aatatgtatt
    11581 attatctggt gctgattatc caatcaaaga taatgagtat atttataatt attttaaaaa
    11641 gaatagttca gtggagttta ttcgtggaat agatctagat caaattaaac ataaagaatt
    11701 ttattataaa catatagatg tatatcaaaa acatgattat cctagaatta ataggaataa
    11761 cacaactgca tttaaaattt ttagagctat aattaatcgt tgtctgagga tgattaaact
    11821 tcccccaaaa attagacacc ataaatttga tttgtatcat ggttctcaat ggtgggcttt
    11881 gtcgaaagaa tgcctaacag aattaataca aatgtatgaa caaaatcaac aagactacct
    11941 gaattttaaa ataggtatgt ttgccccaga tgaaaaattt tttcatacac ttttttttaa
    12001 ttcctcgttc aaaaataaaa atgttattgg aggaccagat ttaccacttg aattgaaaaa
    12061 tattgaagaa actactttac aaacttcgaa attagcaaat attcatatta ttgatccttc
    12121 catgaacaaa tggtttgatg aaagggatat agatcaaata aaagaaagtg aaaaattatt
    12181 tgtaagaaaa gttaaatcgg attactctga taaactatta aatagaattg ataaagaaat
    12241 tttgaaagtt ggaaatatag atgaatagaa tagtacctgt tttagagaag agtttattaa
    12301 gtcgagatgc gtttcgagta ataaatttaa tcatttgtct gctttatttt atgcctagta
    12361 cttttaatgt aactaatatc ccgatgaaaa tagcttttgc ttggggtgga attatagttt
    12421 tgtatgaggt ttttataaag aaaaattttt ttaaaatgcg tttttcttgg ctactgattg
    12481 gagcaatgat tagttttatc ttaactataa tcattaacag agaaaatttt ttaattccat
    12541 ctatttataa ttttggatat ttgctgatta ctttgatagt aatttttcct gcagactttt
    12601 cacaaagtga agaggaaaaa aagaaaaaaa tggtgtattt taataatgtt ttcattatca
    12661 taattttttt agctgcgcta atatctatct atcaatttat ttttttgatt tcttatcatg
    12721 tcccaacagg aacgccagga ttacttgcaa gacaaggttt tattgaacat cggttatttg
    12781 gtgtctatac aagtccaaat gttggagcta tgtttggata tacttctatt attttaagtt
    12841 taattagtgt attaatttca aaaataacaa aaacgattcg tgttttttat atgatgaatt
    12901 ttatcgtaca aatattttat attacacttt cttcgtctag aggtgcccag gtagtaattt
    12961 gttctttttt agtattattt cttttgttgt ttgccaattc aaaatttaga aagagcatta
    13021 gagaagtact acctgtaaaa atcaaatgga tggtaagcat attattagtt ctattggtat
    13081 atttttcttt tggtactaat tatgctaagg attttttagc aacaattcct gtatcgattg
    13141 atagaaaagt agaagttata gagtcaaatg aatcagataa aactccactt ccagaaaaag
    13201 aagtaatatt acagcattct agtgataact ccgaaatttc agctggtcgt tttacgattt
    13261 ggaaagctgc gcttaaagtt ataagaccaa ctttgttatt tggttatgga gagaccgatt
    13321 tctatgggaa tagcgatgca aaatttttga aaaaagtaga tcttgatact acagatgtga
    13381 atgaactaaa aagagcacat ggaaacatgc ataatggatt tcttcaagta cttgtatcaa
    13441 gtggtataat tgcttttata tgtatctatg ctttctatgt gttaaatatc tttagtttac
    13501 tcaaaacatt ttttagaagt aaagtgaatt atgcgtttct tggtattgtt ttaattttta
    13561 tactatctat ttttatagat gaaatggtgg aggctcatgt acttttcaat aagcgcgatg
    13621 tcatttcaat tgttttctgg tattatttgg gaagcatttc ttacttgtat ttaaaaaagg
    13681 agaattaata tgaagacagc tttcattgct tggactcctt tacatttgat taatatatta
    13741 aatgtttatc aaaattttta ccgagaatca aaaggagatt tatttattta ttctgaattt
    13801 gaaaacgcta gaagatatag tgagcgtata aaagaattag ggctatttaa tgatgttgtt
    13861 tttgtgaatc accggaaaat cggttcttcc tttaaacgta aaattaactt gttaactaac
    13921 cataatcaat ttttctcgga tgatttatcc gtttatgatg aaatttttat acagggggaa
    13981 aattatttca caaaaatact tttctccaat gtttacaaaa aaaatccaga tgtaaaacta
    14041 aattatatag aagatggttt gggtacttat ttgaagaaga gtatattttc aacaagtaaa
    14101 aacgttcaaa gagtttttaa aatattaaat aaaaatagca tcttcaaaaa aaaaattgac
    14161 gattattttg tctattgtcc ggaattgtta ctttatgatg taaaaaatat aaaaaaaatt
    14221 cccaaaatag atgaaaacag taaattgatg aaaaacatac aatcaatctt tgggatagaa
    14281 gaagtttttg tcggagataa atgtatcttt tttgatcaac ctttattatc tgatggttat
    14341 ggcatagatg aaacagatat tttcgctaaa gtaaatagta tattttctgg aaaaaaagaa
    14401 actttaatta agcttcatcc tagagcaagg acaaatcgtt atggtgaaaa aaacatattg
    14461 aattccagtt taccgtttga agtcttgcta cttgaaaatg acttctcttc aacacttttg
    14521 attagtccta tatctacaat ttctttttca ccatctatga tgtttgaaaa gacgatcaac
    14581 tctattatgt tggctaaatt aattttaaat gaatatacag cattatctga agataaaaaa
    14641 gaaacattga caaatattgt tcttttctgt gaacattata accgtctatc agaagaaaaa
    14701 attttactcc cagaaaactg ggcagaatta agaaagttgg tagagtatgg gattatttaa
    14761 cacactttcc aagtcaaaat tagttaagtc cagtttctgg tatactatag ggaatttttt
    14821 tattaaggga atttcattca taactattcc tatttttgta aatattacta ctcaagcaga
    14881 atatggtttg attaataatt tcacttcatt tgtatcaatt ttttcgattc ttgttgggct
    14941 aagcctaaat tcggcaatta ataatgcaag ttttgactat aaagatgaca taaatgaatt
    15001 tatgtcatcg gtactttctc tagctacact ttcgttaatt gtgttcttat taatagggaa
    15061 catatatttt ttgttttcaa atgctttttt tgatatgaac caacttgtat ttaatttgat
    15121 gttattacaa agttttgcta gttttgtaat tagttatatc cagtcttatt ttacgattaa
    15181 ctttaaccat tttaaatatt tgattttatc ttttatatct acttttttga atattgcaat
    15241 ctctgtagct ttgatgcaga cattatattt tgatgataaa tatgttggca gagtagtcgg
    15301 cggaacactg tcatttgtgt tgataggttt agtaatttat ttaagaataa tgataaaggg
    15361 tgctcatttt tttgataaaa aacagtggag atacgcttta aaaatctctt tgccgctaat
    15421 cccacattcc ttagcaaata tagttttagc acaattcgat agaattatga ttaattctta
    15481 tttaggtcct gctgcggggg gaatatattc ctacattagt aacataggta ttattctaag
    15541 cgtaatatgg atgtctacta ataacgcctg ggttccatgg ttctatggtg agatgagtaa
    15601 aaataatgaa aaaaaagtga agaaagttag taactattat ttagtagtct ttactttgat
    15661 tacgatgatt gtaatggtag tttcgattga tttagcaaaa tttatggctc cgaaagacta
    15721 ttattctggg ttatctttag tggttccgat aaccttaggc tatttctttc agtttttata
    15781 tagtttacca gttaatgctg aattttatga gaaaaaaaca tcgtttattg cgattggtac
    15841 agtagcaagt gctatagtta atatactatt aaacatgatt ttcataccta ggttaggaat
    15901 aattgctgct ggatacacaa ccgtatttac gtatttttta ctttttattt ttcattataa
    15961 tatcgctaaa aaaattacga ataaacaatt atttgacaca aaaaaaatat gtatcataat
    16021 aatttttgta tcaatttttt ctttgatact tcatatttta atcaatcaaa tgttgattcg
    16081 ttacgttttg acatcattat tgataattag tttagttata tattttttaa agattaagaa
    16141 tcgaattata gatgactata attcatagga ggagatataa gtgtttaaag gaaaaacaat
    16201 attagtaact ggcggaactg gttccattgg aagtgaaatt gttcgtcagc ttttaaaata
    16261 tgaaccaaaa gctatcagaa tttatagtag aggtgaagaa aaacaatttt atatgcaaca
    16321 agagctctca aatcacacta atttgagatt tttaattggt gatatcagag actctcaaag
    16381 gattgattat gcatgtcgtg atgtggatat tatttttcat gctgccgcaa tgaaacacgt
    16441 tccagcaagt gaatataatc ctatggaagc tgtaaaaaca aatgtgatgg gaactcaaaa
    16501 tgtaatagat gcagcgatca aaaataatgt aaaacatttt gtaggtatca gtacagataa
    16561 agtagtgagt cctactaaca ccatgggtgc gacaaagtta ttgagtgaaa aattaataat
    16621 agctgccaat cagtataaag gaaaaacaga aacaatattt tcttgtgtaa ggtttggaaa
    16681 tgtcatgggg tcaagtggat ctgttattcc tctttttagt aaacaaataa aaaacaataa
    16741 agatattact ttgacagatg ttgatatgac acgatttatg atgtcaatac cggatgctgc
    16801 aagattagtt ctgtctgctg ctatgaattc aaaatttgga gaaacatatg tcttaaaaat
    16861 gccggcaatc aatattttaa ctttagctca atcattaata aaaatatata atgatacaca
    16921 tgatgaaaaa tatagaggtg aaataaaagt tgtaggtatc aggccaggag aaaaattata
    16981 tgaagagcta atgactacag acgaaattga acgctcatat gaaaatgata aaatgtatat
    17041 cattccacca cactatcatg ctactgacga actgtacaaa gattatgaaa aaattaaaat
    17101 cactgcatac tcttcagatg caacagaatt aatgagtgga caggaattta ttagaatcgc
    17161 aaaagagaat aatgtcgtga cttggtaagg agttttatga tgaaatcaga agtatatgta
    17221 attgcagaaa ttggtgtaaa ccataatgga agtctagatt tagctttaga aagtattgat
    17281 aaagctaaag aatgtggagc taacgcggtt aaatttcaaa catttaaaac gaataagcta
    17341 gtttccaaaa aggctccaat ggcaaaatat cagaaggata atcttaaaga ggacagttct
    17401 caatttgaaa tgctaaaaaa attagaatta tctcaatctg attttattag aataaaagat
    17461 tattgtatac aaaataaaat tgattttttg tctactcctt ttgatgaaga aagtgcagac
    17521 tttctaaaac aaattggtgt acaaggattt aaaattggct caggagattt aacaaattta
    17581 ccttttctta gaaaaataga tatgtatggg ttgccagttt tattatctac aggtatggct
    17641 gatattcatg aggtcagtga ggctgtagat tgtttcatag atagtccagt tactatttta
    17701 cattgtactt caaattatcc ggctagttct gaagatatta atttattggc gattaacaca
    17761 ttaaaagaaa tgttcgggat acccgttggg tactccgatc attcattggg atatgatgtt
    17821 ggtatttgtg ctgttgcgat gggtgctaag gtaattgaga aacattttac cttggataag
    17881 gaactacctg gtccagatca taaagcttct ttagatcctc aggaatttgc agattttgta
    17941 aagcatatta gaaacactga aatattttta ggtgatggtg ttaagcgagc aatgccttct
    18001 gaacttagta caaaagaagt atcaagaaaa agcctagtgg tcactgagaa tttaaatgtg
    18061 ggagatattc ttacagagaa atctcttaca ataaaacgtc ctggaaatgg aatagctcct
    18121 aagtttttat atcaatatat tggcaaaaaa gttaaaagac caataagtgc agatagtgtt
    18181 ctgcttgagg aagatgttga atgaaaaaaa tacttatagt aagtggaaca cgagctgatt
    18241 atggaatata taaacctgtt gctgagaatt tactacaaga taattgggat gtatcatttg
    18301 ttgtttctgg aatgcattta tcccataaat atggatttac taaagaattg atcttagctg
    18361 acggatttag aattagtgga gaagttcaaa gtttgttttt agagaacaat aagggaaaca
    18421 tggctcggtc tgtggcatta gagataaatg gtttcacaaa tatatttgaa caaactagcc
    18481 ctgattttgt attattacta ggggatagag gagaaatgtt ggcagctgcg atagcttgtt
    18541 tgtatcttgg aatcaaaaca gcacatattc acggaggcga agtgtctggt actgtagatg
    18601 aatcaataag acatgccata acgaaaatag catctgttca ttttgctgct acggaaaaaa
    18661 gcaaagagcg tttaataaaa atgggggaag attcttggag agtttttccc gtcggagctc
    18721 ctagaataga tactatttta aataatagat tacctagttt tagagatata aaagaaaaat
    18781 atcatctaaa atttgaaaag aaaaaatacg ttttgcaagt atttcatcca gttgtaaccg
    18841 aactagaaaa tatagaaaaa caaattttag ctttgatcaa ttcaatggaa caacaatctc
    18901 aaccaattat ttgcatttta cctaatagtg atgctggtag cgaaattatc agaaaaatgt
    18961 accagaaata tttaaaaacg gatattattt atattacgaa tttagagccg gaggaatacc
    19021 tgactatatt aaaagagtgc aaatttatga tcggaaattc ttcttctggg ataattgaag
    19081 ctgcatcatt caaaatacca gtaataaatt taggaaccag acaaaatgga cgagaacaat
    19141 ctaaaaatat tataaatgca aatctaaatg aaaatgaaat tgaaactgct ttgaataaaa
    19201 tacaagatcc tcagtttata aaaagcttga aaaatgttaa gaacatctac ggtgacggca
    19261 acagttctag aagaataaca aaaacattga atcaaatatt gaatgatggg gaagatatta
    19321 agtggattca aaaacaaata gcttattaaa atatactagt gatccataca ttattattgg
    19381 ggctggcgga cacgcaaaag tcattattga aaccttaaga ttagaaaata agttaatata
    19441 tggatttttt gatgataagc aaaataaaat gcaagatctg aaatatcttg ggaaaataaa
    19501 cgaattgaat agctgggcgg atagcaaaaa aaaaatctat aaatttattg tagctattgg
    19561 tgactgtgta gtaagaaaaa agattataaa aaaattgaat atgccaagtg agcaatatgg
    19621 aatagctgtt catccaagtg ctatagtggc aaaagaaatt tcaattggtt atggaactgt
    19681 tatttttgcg aatgctgtaa ttaacccaga tgctgtaatt ggagagcatg ctataataaa
    19741 cacaggtagc attgttgagc atgattgtag aattaataac tatgttcatt tatctccagg
    19801 tgtatgctta gcgggtggag tacatgtagg tgtaggaact caaataggaa ttggttctca
    19861 atgtatccag atgaagaaaa ttggatcttg gtgtatgata ggcgcaggga gcactattgt
    19921 taaggatatt ccctcacatt ccttagctta tggcaatcca gctaaaatta agaaagaagg
    19981 aattaatttt gaattctaga attttattat caagtcctca tatgggagga acagaagaaa
    20041 aatatgttgc taaggctttt aaagataatt ggatagcgcc attaggtgaa aatgtggata
    20101 aatttgaaga aagtattaca aaatatactg gttctaaggg cggagcttct gcgttaagtt
    20161 caggtacagc tgccatacat cttgccttaa gactgcttaa tgttggaaaa aacgatattg
    20221 tctttgctcc ttcatttact tttatagcta cagtaaatcc tattttatat caaggggctg
    20281 taccagtgtt cattgactca gaacctaata catggaatat gagccctgtt gcactagaga
    20341 gcgcattaga agaagctgaa agaaacaacc aattacctaa ggcaatcatc gtagtgaatt
    20401 tatatggtca aatggctgat tatgaacgaa ttttagctat tgcaaaccaa tttaatgttc
    20461 cagtgataga agatgcagcg gaatcgttag gttctactta taagggaatt tcgtcaggct
    20521 tatttgggac aattgggatc tattcattta acggtaataa gatcatcaca acctcaggtg
    20581 gaggagctct agtgtctagt gataaaaaat atgttgagca ttcaagattt ttagcaacac
    20641 aagcaagaga tcaagcaccg tattatcaac atagcgaaat aggttataat taccgtctaa
    20701 gcaatatttc tgccggtatc ggacgtggac aaatggaagt attgaatgat agagtagcta
    20761 aacgaagaga aattttcaat cgatataagg aagctttttc tggaattgat agaattgaaa
    20821 tgatgccaga agtggatggc atggtgccaa atcgttggtt gtctacttta acgatcaatg
    20881 attataattc tattgatcaa gtagttaacg taataaataa actaaatgaa aaaaacattg
    20941 aaacaagagc tttgtggaaa ccactacatt tgcaaccagt atttcaaggg gtaaaaatgt
    21001 attaccatga taataatctt agtgtgtcag aaaagttatt taatagcggc ttatgcttac
    21061 cttctggaag taatatgaca gatagtgaac aagaatttgt tattgatgag tttaaaaaaa
    21121 tattcaagta ggtgtgatat tttatgaaca taggaattat tggtttaggt tccatgggga
    21181 aaagaagact tagactcatt caagaacact ttaatgatat tttactatgt ggtgttgata
    21241 ctaatgaggc gagacgaaag gaagttgaaa aggaatttgg aataccaact tataatagtc
    21301 taacagaggc aaaaaatttg tttgaaataa attcagtttt tgtttgtaca tcccctataa
    21361 cccatgaatt tattataaaa gaggctttaa atttagattg taatatcttt acggaaatca
    21421 atttattaaa tgaatattat gatgaaataa tcgaagtagc taaaaagaaa gatagattac
    21481 tttatctatc ttctacattt ttgaagagaa aagaaattca atatattaag tctaaagtga
    21541 cgcataataa aaaaatttct tatcaatacc atgtaggaca gtatttaccc gactggcatc
    21601 cttgggaaga ttatcgcaat ttttttgttt caaacaaaaa aactaatggg tgtagagaaa
    21661 tattcgctat tgaattacct tggattatag atacatttgg gaaagttaaa tcgtttactg
    21721 taatgaccca gaaattatcc aatcttgata ttgattattc ggacagtttc actcttatta
    21781 ttgagcatga aactggtata gttggaactt taagtgtaga tgttgtttca agagtagcta
    21841 aaagaaattt aactataatt ggtgaaaaga ttttaataga atgggaaggt aacccggatt
    21901 ctctattttc atggaatgaa gaaacttcta gtatgacaga tattcaattg tacgatgagg
    21961 ttatgcatga taataattat tcacatacta ttattgaaga tgcatattta gaggagatta
    22021 aagaattttt cacgcttttg gaaaagaaaa tggaacccca atatactttt gaaaaagata
    22081 agtatattat taacttaatt aacgacattg aggtaaatta atgatgaaag taattttttt
    22141 tgggttaggg tcaattggaa agagacatct aaaaaatcta ataagctatg gaaaaaagaa
    22201 ttctattaat tttgatataa cagcttatag tagcagtgga aaaaaagagt ttgaagaaat
    22261 aacgtatatt caaaatagag acgatttgga tacacattat gatatagctt ttattacaaa
    22321 tccgactttt aagcatctgg aaacactaaa tgtaattgtt gaaaaagttg attacatatt
    22381 tttagaaaaa cctgcttttt ctgagagtat tgatcttact caatataatt atgattacaa
    22441 aaatatttat gttgctgctc cactgaggta taaaaatatc atggaagttg ttcgtaatag
    22501 tattcaaagt aaaaaagtat attctgtaag agctatttgt tctacttatc ttcctgattg
    22561 gagaaaaggt actgattata gaaataatta ttctgccttt aaatctatgg ggggaggagt
    22621 agaattagac tgtatacatg aattggatta tattataaac ctatttggtt tccctaaatc
    22681 agtaaaaaaa cagtttggta aatattcgaa tcttgaaatt aacagtaatg atttagcaac
    22741 atatatattg agatacgatg ataaaattat agaaattcat ttagattatt ttggaagagt
    22801 tcctacaaga aaatttcaat tgtttacttt agatgaatgt atcaatgttg acttattaaa
    22861 taataaaata agttttgaag aaaacattgt taaagaaatg cctgaatctg ctaatgatat
    22921 gtatgagaag gagttgaaat atttctttga aaacgtagta acaggcaaag aaaactggaa
    22981 tgatttatat catgcaaacg aagtattgaa aatagctgag gagaaataaa tggaaatttt
    23041 atttactatt tgtggtagag ctgggtctaa ggggtttaaa aataaaaatt tgaaatattt
    23101 ggcaggaaag cccctagtcc atttcgcttt agcaatgata gatatctatc aacaaaaaca
    23161 tcctgaacat aattgcacga cttgtttgaa tacggacagt aatgagttag tagaattgac
    23221 gactaagtta aatccgtctg tgaaaattgt agaacgtaaa cctgaattag ctacagatac
    23281 tgtagggaaa attgaagtga tacgtgattc attcttacaa ctagaaagag aagataatat
    23341 atttgattta attatagatt tagatttgac ttcaccttta cgtgaagttt ctaatcttga
    23401 agaattaata gatgaacatc taaaaaattt agataaagac gtctactttt cagttgtttc
    23461 tgcaagacgt aatccctatt ttaatatggt aaaaagaatt gaaaatgaag ttactatagt
    23521 taataaatca agatacacat ctaggcaaca gacacctgaa gtttttgaaa tgaatgcctc
    23581 aatgtattct tttaaacctg aatttctaaa aaaaagtaat tatatttttg atgggcaatg
    23641 tgggataata aaaatgagag attatctaat tttagatatt gatagtgaag aagattttaa
    23701 atggttagaa tttttgtttc ctaaattttt agaagattct tcggagcttc aagatatcta
    23761 taattattta tatcggaggt aaaaggatga gctgttatct tatcaccggt ggggctggct
    23821 tcattggttc taccttagcc aatcatttag gagaagaaca tgtggtaatc gtcgtcgatg
    23881 acttatcaat gggaaaagta gaaaatcttg atatgacgaa aaatatcact tttattgagg
    23941 gagatgtcgc tgagaaatcc ttgatggaag agatcatgaa agctaataaa tttgattata
    24001 tctttcattt agcagcagtt gctagtgtgg cagattcagt tgcccgacca gtagaaacac
    24061 atcgtgtgaa ttttgaaagt gtattaatga ttttagaatt gatccgcaag tatcaacctg
    24121 atttaaaacg gatcgtgttt agttcttcag cggctgttta tggggatgaa ccgactttac
    24181 caaaaaaaga agagtccgtg attcgcccat tgacgcctta tgcggttgat aaattcgctg
    24241 cagaacaata tgtgctagat tattgtcatt tatatgatgt acccggtagc gcagttcgtt
    24301 ttttcaatgt ctatggtcca aatcaaaatc cgaattctcc atacagtggt gtgatttcta
    24361 ttctcgtaga tcgctataag aaacaaatcg taggagaagc aacttcattt acattatttg
    24421 gtgatggaag ccagtctaga gactttgttt atatagatga tgtaatccaa gcattacttt
    24481 tagttgcgaa tgaggaagct gcactgggga aacaattcaa tgttggaacg ggtaaagcaa
    24541 ccacactttt ggaattgatt catgcaatca atgaaattct cggtgtagaa ttgacacttg
    24601 aatacaaaga agagcgttcg ggtgatatcc atgactctct agcagatatt actaagatcc
    24661 agtcaattgg ctatcaaccg aaatatggta ttttaagtgg aatgactaat tatttgaaaa
    24721 ctgaaatcaa ttaaaacata ctaagataag attagagggt aaattcaggc tctttgtcaa
    24781 taaggactga tgagttttgt aaaatcaaat ctgggataga a
//
LOCUS       DAPBBR010000040        24336 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPBBR010000040 DAPBBR010000000
VERSION     DAPBBR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.040"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(132..2477)
                     /locus_tag="RD488_001830"
     CDS             complement(132..2477)
                     /locus_tag="RD488_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7657902.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            2756..3658
                     /locus_tag="RD488_001831"
     CDS             2756..3658
                     /locus_tag="RD488_001831"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDT7657903.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            3869..5644
                     /locus_tag="RD488_001832"
     CDS             3869..5644
                     /locus_tag="RD488_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDT7657904.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5710..7296)
                     /locus_tag="RD488_001833"
     CDS             complement(5710..7296)
                     /locus_tag="RD488_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDT7657905.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            7547..7771
                     /locus_tag="RD488_001834"
     CDS             7547..7771
                     /locus_tag="RD488_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDT7657906.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7913..9664
                     /locus_tag="RD488_001835"
     CDS             7913..9664
                     /locus_tag="RD488_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7657907.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            9664..11448
                     /locus_tag="RD488_001836"
     CDS             9664..11448
                     /locus_tag="RD488_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7657908.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            11783..12635
                     /locus_tag="RD488_001837"
                     /pseudo
     CDS             11783..12635
                     /locus_tag="RD488_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            12732..14618
                     /locus_tag="RD488_001838"
     CDS             12732..14618
                     /locus_tag="RD488_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7657909.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(14659..15561)
                     /locus_tag="RD488_001839"
     CDS             complement(14659..15561)
                     /locus_tag="RD488_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7657910.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            15791..17194
                     /locus_tag="RD488_001840"
     CDS             15791..17194
                     /locus_tag="RD488_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7657911.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            17191..18627
                     /locus_tag="RD488_001841"
     CDS             17191..18627
                     /locus_tag="RD488_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7657912.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            18772..19698
                     /gene="trxB"
                     /locus_tag="RD488_001842"
     CDS             18772..19698
                     /gene="trxB"
                     /locus_tag="RD488_001842"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDT7657913.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            19911..21638
                     /locus_tag="RD488_001843"
     CDS             19911..21638
                     /locus_tag="RD488_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDT7657914.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            21654..22004
                     /locus_tag="RD488_001844"
     CDS             21654..22004
                     /locus_tag="RD488_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7657915.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(22098..22958)
                     /locus_tag="RD488_001845"
     CDS             complement(22098..22958)
                     /locus_tag="RD488_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDT7657916.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            23050..23478
                     /locus_tag="RD488_001846"
     CDS             23050..23478
                     /locus_tag="RD488_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7657917.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            23640..23816
                     /locus_tag="RD488_001847"
     CDS             23640..23816
                     /locus_tag="RD488_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDT7657918.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            23843..24289
                     /locus_tag="RD488_001848"
     CDS             23843..24289
                     /locus_tag="RD488_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDT7657919.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7708 a         4352 c         5186 g         7090 t
ORIGIN      
        1 gtttttcaca tttttacata aatttgtctt aatatcgtag atgtaagctt ttgaacacca
       61 tttattcgga aaaagggagc tgtgacaaga tttttgtcgc agctcccttt aattctgatt
      121 aatctattag atcaatcatc tttatcgtct gattctttgg tctctggatt cgctctagca
      181 taagctgaag cggtgttcca gtaatctgta tagttttcat cagtaccgcc tacgccgaat
      241 ttaaaggcgc ttttcttcgg accatttttt gcccaaagtg actccactgt ttttcctggc
      301 gtttggatgg attttttatt gacagtaact tttccagctg tttgtcctgt gaacccagat
      361 acttttttct tcatcacatc ggatgataag tcaaatttct catcagtgcc gaaaatctca
      421 gggtttgctt ggtaagcttg attgattaga ttggcaagat aattagccga acgtattctt
      481 gcttggctgt ccattccagt attgtcatcg tgtcctgccc aactactgat agtgatagat
      541 ggagttgaga cgatcagcca tgaatctcgg tattcattgg tagaaccagt ttttccgacc
      601 caatctgcat ttcctagatt tccgtttaag cttgagatga catctttgaa tggtgtagtg
      661 attttttcat tgatcacact acgcatcatg tcattcatga tcgatgccgt tgcttcggaa
      721 taaatacgga cagaattact ttcatgttta taaatcacat tacctgcatt atctgtgatg
      781 gaatcaatga tatagccttc ttcgtagact ccaccatttg ctaaggcctg gaatccattt
      841 gtctgttgaa gcgtcgttac atctactgtc cctaaaggag ccgattcaac gccccaatta
      901 tcatttgctg ggtagttcat cttcgccaag tagtgctcgt aagcgtattg tttcgatcca
      961 ccggaattca acacatcttg atataagtga taagctggga tattgttgga ccattccagt
     1021 gactcacgga cggtttggaa ggtgttcgac ccttcattgg tcgcattgac gattttctca
     1081 ccagcatttt ttccttcttg ccaagtcgtt gcataatctg atacacggga ttctgatccg
     1141 acaagtccca tatcgattgc aggaccgtaa acaagaaccg gtttgatgga tgaaccagct
     1201 tgacgttctg tatcaaaggc gtggttattt tgattctggc tgtaattccg accacccacg
     1261 aagccataga tacgtccggt tctgttatcc atcaatacat ttccagtctc cacttggcta
     1321 ccagcaccat catctaacat gtagccataa ttttctacgc cggtttgtaa tgcagcatag
     1381 atatctttat cgatcgtcga atggatcgta tatcctttgt tttggatcgt ttgctgtgct
     1441 ttttgataat aagcttcact gaccgatgaa tctgacatat cagcattatc tttttctgcc
     1501 aattgttgtg caataatcct tgttgcttcg ttcatcacgg tataatacaa gaattctctg
     1561 tcagtctgtt ccgcgatttg ttgtgggaga aagtcttttg taagatcata ggctttcgct
     1621 tcttcgtatt gttctttcgt aatttgtcct tcacggtaca tactgaataa aacaaaatct
     1681 tttctggcaa gaccggcaga aagatcttct tttagcgcgc ctgtattcgt gtatggacta
     1741 tacgtgatag ggctttgagg caaaccagcg atataagcag cttgtggcag agtcacatcc
     1801 tttgcatcta caccaaagat tcctctagca gcttcctgga ctccagcaat attttgcccc
     1861 ttattattcc gaccaaatgg tgagacattc aaatacgtag taatgatctc attttttgaa
     1921 aagtgttttt ctacttgtgc agaaagaacg atctcgtttg ctttacgttt gaatgttgtt
     1981 tcatcggtta ggatctgttg tttgactaat tgctgtgtca aagtggatcc tccagacgag
     2041 ccgatgccag tcgcttctga aactagtgct cgtaaaacag ctttagggac ataaccttga
     2101 tgtttatcga agtattcatc ttctgtactg ataatcgcgg ttttcaataa aggcgaaatc
     2161 ttatcagatg aaatagtcgt ccgcatcaga tctgtctgga tttttgatat ctctgtatta
     2221 tctgcataaa caatctttga cgtttccgta atgtttccta gttctgtctg cagttctttt
     2281 ttagtcggca attgtgtgtc ttcgacaaga taggcaaagt agccagcacc tattccgata
     2341 cctagagctg cgaacaacaa aagaagaaca gtaataaaaa cagtcaatga ttgaaacact
     2401 ctaaaaataa tcttaggaac aaaccatttt tctttttttc ttctattctg tttttttcga
     2461 gtatttttgc gtggcaaaag ggtcacctca actaatggtt ttatttcgct aattatagca
     2521 aataatagga caaaaaaaca gacaaggctg tttttgacag gaatttcttt ttcgaatgag
     2581 ataaaacgtg aggaaatgat cttttttatg aaagagttct taagcttttc tttagggaaa
     2641 gtttcagtta ctatggagaa cagggcaaag aaaaacaaac cattttcttt gtacatcatc
     2701 ttatcaatat acaggaattg ttcgaaacaa ttgcctttca aggaggaatc catccatgtt
     2761 attaggctca catgtcagca tgagcggaaa gaaaatgctg ttaggcgcgg cagaagaagc
     2821 agccagttac ggatcttcga cctttatgat ctatacaggc gctcctcaaa atactagaag
     2881 aaaagctatc gaagagatga atattgatgc cggaaaagca tttatggcag aaaacggact
     2941 aacaaatatc gtcgttcatg cgccttatat cattaatttg ggaaatacga tcaaaccaga
     3001 aatgtttcca tttgctgtac aatttctgag agaagagatt gtccgtgcgg aagctttagg
     3061 tgctactcaa atcacccttc acccaggcgc tcatgtagga gcaggggcag aagctgggat
     3121 tgctagaatt attgaggggt tgaatgaagt tttgacaaaa gaacagacgg cacagatcgc
     3181 tttggagacg atggcaggga aaggtacgga aatcggtcga acatttgagg aattagcgca
     3241 aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt acttttgata catgtcatac
     3301 gaatgatgcc ggatataata taaaagaaga tttttcaggt gtaatggaag agtttgataa
     3361 ggtcatcgga ttagatcggc ttaaagtact gcatatcaat gattctaaaa atccacaagg
     3421 ttctcataaa gatcggcatg ccaatatcgg ttttggaaca attggatttg acacattgaa
     3481 caaaatcgtc catgatccaa tgtttgacaa catttcgaaa atattagaaa ccccatatgt
     3541 cggtaaagat aaaaagaaag cttacgcacc atatggaaaa gaaatttcca tgttcaaagc
     3601 gcaagcattc gatcccgaag tgttccctga gttattagca gaagaagtca cactttaagt
     3661 tttctacctg acagcaacaa aaaaggattg ggcagtctgc cttgtccttt tttgtttaag
     3721 aaacaaagga gtgctttttg cattcgtttt cgccatgctc cttttgcccc ctctttttaa
     3781 attcagacaa acagggtata ctgatagaaa agtaaaaaac gaaaagtttc acaaacaagt
     3841 agcaaaacgt gattgaaagg acgaaaagat gctgaacatt ttaaacccct tgatcgacca
     3901 actaaaaaag aaacatacat actttattct tggcatagcc gtattattta caattattcg
     3961 gttgtattta tatagtaaag caatctatgg aacagatatg tcggcgacct atgatgatca
     4021 gctgctgatt cactatgctc aaaatatttt ggatggtaaa tggctagggg agtatacgac
     4081 tacaacactt tccaaaggaa tctcctacag cttattttta gtacttgcac ataaactgca
     4141 tctttcttat gcagttttgt tcggcatgtt cagtattttt gccagtatat tggttgcact
     4201 cgcgtttaaa ccgattgtga agaacaagta tcttctttta agtatctatt tttatttttt
     4261 gttttctccg attagtttta cacatgaata ttccactcga acatatcgta atgccctcgt
     4321 gattccggct gttgagatca ttatcgcttg tttattagct atttattacc gcaaatacgg
     4381 ttctagcaga aaattgctgc catggttttt agggctttct gtcgcttttc ctttcttttg
     4441 gttcattcgc gaagattcta tctggcttct tccttttact gtagtagctt tgggtatcag
     4501 tttcgtccag atcttgctag ggcaagactt ttctttcaaa gaagtaaaga agttaaaaaa
     4561 acgactcttt cttctctcga aacgggaatg gctgaaactt tcattgtttt tacttcctat
     4621 agttggcttt tccatcgtct atcagtggat cgaatataaa aatgagacaa catacggtat
     4681 tgcaaccatc aatgaccgtt ccagtggaga atttggacgt ttgatgaaac aactgatccg
     4741 aatagatgat gaaacgaact tgaataaaga aaacagtgag atatgggtct cacatgctgc
     4801 actaaataaa gcattagccg catctcctac attccatact gtttctaccc gtattgacga
     4861 attatatacg actcacgcgt ggactcaagg tggaaaagta aaagaattac ccggagatat
     4921 catcttttgg gcattgcgag atgtggtaag cgaatctggt tattaccaaa acaatgcaaa
     4981 agaaaccaat gatttttgga aaaaagtcaa ccaagaatta gaagaagcct atcacaaggg
     5041 aaccatcaaa aagaaaaaag agttctatct gatgggatca ggagatggaa agacgatgag
     5101 tgatctgcca atcgtattcg atttccttca atcaggatac gcttatgcat ggcgatataa
     5161 agatttccat caaggaggaa attatagttt cggaacgcaa gaacaagtca aacaggctca
     5221 agaattatta aaccttccgc taatggagaa ttggatcgat agtaatgaac cgagaacacc
     5281 taatttccaa ttaacaaaat cagcaaaagt cgcgaatgtc atcataaaaa tttaccaagt
     5341 tctggctatt cccgtgctga ttgcttcaat agcagggata ttacttatga tactaggaac
     5401 cgtatttgca aaagctgatc gtgcctatta tagttcctct ttgattgtgg tcaccggatt
     5461 aatactgaca caattggttt ttcttttcgg tgtctcatgg ttttgttctt atgcgccaga
     5521 aaaaaaggac tattttttaa gtgtctacac tggtgcaggc gtgccattaa cgcaattcat
     5581 cgtagtaaca agcatgctag ttttcagtaa attaaatctg aaaaaagctt tatcttctaa
     5641 ataaaaagac ccttggtagc tagattttta acctaactat caagggtctt tgtgtggaaa
     5701 aatcagtttt tattcgattt cttctaccgt ttcctgcaaa agctgttcat attttttgtt
     5761 tcctttatat aaatcaccaa tcgtccatgc caacaggaga aggacaagaa caatgattac
     5821 ataagcgatg tgatcagcca atgctagttg agcggaagtg gcttgctcgc cgaagaaact
     5881 ttcgatctgt cctggtaatc ctcgtaagtt caagtaagtt agactaatca cagagaacca
     5941 gccaagaagt tttacgatga atgaattttt aaatcggcta cccatctccg cttggctgtt
     6001 ggtcatcatc agtaaaggaa tcatcgaaaa tggcaacgca aaagccaaga acacctggga
     6061 ttcattcatt aagttattca aagcggcatg ttcttcgatc gttccttttg tacttgtaaa
     6121 caaaacacaa atcaatacag gaatcacaga aagcaatcgt gtgaccagtc ttcttagcca
     6181 aatcgggata cgcatatgga tgaatccttc catgatgact tgaccggtca acgtaccagt
     6241 aatagtagag ttctggccag aagcaagaag tgctacagca aataaagtgg acaagatacc
     6301 agattttgct acagcaatca aaataccatt gctcatagct gatggatcag ataaagcttc
     6361 atacagacca aaaaaggaag gatcttggac agaaccggtt ttgaagacag cgacacccat
     6421 gatcaatagc agtgcattga ctagaaaagc cattgacaac tggatattag aatcccaagt
     6481 agaaaaacgt acagcttgtg ctacatcttc ttcgttttgg tgatcgatct tccgagtttg
     6541 tgaaactgct gaatgaagat ataagttatg cggcatgact gttgcaccaa taatccctaa
     6601 agctccagtc agcggagttt cgccgccgat gaccggtgag tctgagaatg tatgactgtt
     6661 agggataaag ccagcaaata aactgtgcca atctgggtta gacaagccaa cttgatagac
     6721 aaaaacgaat aaaatgacga aaattaagca gacaaccagt gcttcgatct tacgaaaccc
     6781 gacttttgtc agtagtaaga gaacgaaaac atctaataca gtaataaaga cggcaatcac
     6841 caatggaata tcaaaaagta agtagagggc gattgctgca ccaatgactt ctgcgatgtc
     6901 tgttgccata atggctaatt cagtcaagat ccataaaatg acacccaatg tcttacttgt
     6961 ccgtgctcgg attgcttggg ccaaatccat ttgggtcacg attcctaatt ttgctgccat
     7021 atactgtaaa agcatagcaa ttagactaga catcaaaata actgacatca ataaatattg
     7081 gaaattttgt ccaccagtga tcgaagtgga ccagttacct ggatccatat aaccaactgc
     7141 tactaatgca cctggtccag agtaagcaag aagtgtttta aaaaaacttt ttccctttgg
     7201 tacatccact gttccattta cttcagctaa agataaacca tttgtatgtt caataagtcg
     7261 atgcttatga aattgtttgt tggattgatt attcaagaaa aaaccacctt tcctatttat
     7321 ctacgattac attctacacc tcagaaagaa aaaattaaag aaaaagattc ggtatgccta
     7381 attttttttc gtggtgtgtc ttgctggtta atgaaagaaa ttttgttctt ctctaaaaaa
     7441 accactattt tttgcatgaa actaaagaat acgcctttct tttttcaata aactttagta
     7501 aaataaatca ttgagagcaa ttcggaaata gaaaggagag atttatatgg tatcaacagg
     7561 tattgtcgta cttattgcta ttattgcttt gctaatcggc gcagtaggtg gctttttcct
     7621 agcgcgtaaa tatatgaaag actatttaga aaaaaatcct cccgttaatg aggacatgtt
     7681 gcgatcaatg atgatgtcaa tggggcaaaa accatctgag aagaaaattc gccagatgat
     7741 gcagcaaatg aagaaccaag ggaaaaaata ggttctgacc caaagacttt ttgcgggctg
     7801 attttttcag tccgtttttt atttcgtaat ttgttagact attcagacta ttcagcaaaa
     7861 aagacaagca cagacaatcc tatgctcttg ataaagacaa aggaggagta aaatgtcgat
     7921 ttttagaaaa ttaggttggt tttttcgtca ggaaaagaaa cattatttaa ttgggatttt
     7981 ctccctattc gcagtggcct tggtacagtt agttcctcca aaagtgattg ggatcatcat
     8041 tgatgagatc gccgataaga atttatcaat aaagatcatt tcctggtgga tcttattatt
     8101 gatccttgca gctttcttac aatatctttt tcgttatatc tggcggacga atatttgggg
     8161 aagtgcagct cggttggaga gagaacttcg gcagcagcta ttcaaacatt ttacagaaat
     8221 ggacaatctc ttttaccaaa aatatcggac tggagatttg atggctcatg caacgaatga
     8281 tttgaatgca atccagaatg tagcaggagc tggaatcttg acctttgcag attcagtgat
     8341 tacgggcgga acaacgatca ttgcgatgat tttgtttatt gattggcgct taacactgat
     8401 tgcgctgatt cctctgcctt tgctagccgt tacttcacga gtgctggggt caaaactcca
     8461 cgatgctttt cgtgattcgc aagaagcttt ttctagtatc aatgataaga cacaagaaag
     8521 tatcactggg atcaaagtca ttaaaacatt tggacaagaa aaagaagatc tcgcggattt
     8581 tgaagaaaag attgaagatg caattattaa aaacaaacga gtcaattttt tagactcctt
     8641 atttgatcca ttcattacct tgattatcgg tctgtcttat gttgcaacaa ttattttagg
     8701 tggaaagtat gtcttggaag gcacgatctc aatcgggcag atggtctcat ttattagcta
     8761 tatcggtatg cttgtttggc cgatgtttgc gattggtcga ttgttcaacg tattggaaag
     8821 aggaaatgct tcttatgatc gcgtcaatga acttttgcat gaaaagacgc atatcgtgga
     8881 acaactgggt gcagtgcaga ccccggcaaa aggcgagctg aatgtagcta tttcctcttt
     8941 taactatccg aaagaagaat caccagcatt agaacaaatc aaatttgcga tccaagaagg
     9001 agaaacatta ggtattgttg ggaaaactgg tgcgggaaaa acgacaatca tcaaattact
     9061 gatgcgtgaa tacgatgatt atcaagggaa aatccaattt ggcggacgtt cgatcaaaga
     9121 atattcattg aatgctttat taggatcaat cggttatgtg cctcaggatc acttcctgtt
     9181 ttcgatgacc attcgagata atatccgttt ttctaatcca aaactttcag aagaagaagt
     9241 agagcatgcg gcttctttag catttatcaa caatgaaatc aaggaattgc caaaaggtta
     9301 tgatacctta gttggagaac gtggagtctc tttatctggc ggacagaaac agaggatttc
     9361 gattgctcga gcattgatca aaaatcctga attgctgatc ttagatgatg cactttctgc
     9421 agtagatgcc aaaacagaag aagctatctt gcataattta aaagaaataa gaaaagagaa
     9481 aacaaccatc attgcagctc accgtttaag cagcgtgatg catgcaaaag aaatcattgt
     9541 tgtcgatcaa gggaaaatca ttgaacgagg aacccaccac gagctgcttg cattaggtgg
     9601 ctggtatgaa cgaatgtggg aaaaacagca attagaagcg aagatagaag gaggcgaggc
     9661 ctgatggatg aaaattatca atcggaatgg acaaaatcga ttccacttaa agaacagaag
     9721 aagatcatca aacgactgat gaagttcgcc aaacctttta gaagaacgtt catcgttgct
     9781 atcttatttg cgtttgccct gtctgtgatc aatgtcctat tgccaaggat catccaaact
     9841 tttatggatg atcatctggc taaacagtca gctacgacac aagttatttt gttttttgct
     9901 ggtgtgtact tgtttggagt catagtcaaa agtatcattt ggtttttcca atggtatttg
     9961 tattccatgg cttcattgaa gacctatcag tatgttcggg taagattatt tgaaaagctg
    10021 catacactag gtatgcgtta ttttgaccag acaccggcag gatcgaccgt ttctcgagtg
    10081 acgaatgaca cagaaacgct atttgaattt tggtatgtct ttttgatggt attgactggg
    10141 atctttgcag tcgtttcttc tttcgttgcc atgtttcaaa tcaatggaga aattgccttg
    10201 tggactttgg tgttcttgcc gattttagga atcgtcatct ggtattacca gaaattcagt
    10261 tctcgtattt accgaaatat gcgggaaaaa ttaagtcagc tgaacacgaa attgaatgaa
    10321 tcgatttccg gcatgcgtat tatccagcag tttcgccaag aagctcgttt agctaaagaa
    10381 tttgaacaag tgaacaacga gtatttagac acgcgctatg cgatgatcaa aacgaattcg
    10441 attctgttaa gtccaatcat caattttctc tatgcattgg cgattgcgtt ggcgttgact
    10501 ttgtttggga tcgatgcgtt gcattctccc gtagaagttg gactgatcta tgcatttacg
    10561 acctatgtcc aggaattttt taatccaatg tctcaaatga tggacttttt gagcaccttt
    10621 acagatggga tggttgccgg tagtcgtatt ttgaaaatca tggatacaga agaatatgca
    10681 ccgcaacaaa atcctggagc agatcaagcg attacttcag gtaagatcga gtttcgcaat
    10741 gtaagctttt cttatgatgg agagcacaat gtattgaaca atatctcttt tgtcgctaat
    10801 ccgggtgaga ccgttgcatt agtggggcac accggaagcg gaaaaagctc gatcatcaac
    10861 gtattgatgc ggttttacga attttatgaa ggccaaatct tgattgatga tcatgacatt
    10921 cgagaatatc caatggaaga gttacgtaag aaaatgggat tggtcttgca agatgccttc
    10981 ttgttttatg gagatattgc aggaaatatc cggatgatga atccagctat cacagacgaa
    11041 cagattcgcc atgcagctga gtttgttcaa gcaaacaagt tcatcgatga attaccaaaa
    11101 ggatatcact caaaagtgat cgaacacggt gccagctatt ctagtggaca acgacagctg
    11161 atcacttttg cgcgaacaat cgtgacagat cctaaaatac tagtattgga tgaagcaaca
    11221 gcaaatatcg atactgaaac cgaaggattg atccaagaag gattggcaaa aatgcgacaa
    11281 ggacggacaa cgatagcgat tgcccatcgg ctgtccacga ttcgggatgc agaattgatt
    11341 ttagttttag acaaaggtca tatagtagag cgtgggaatc atgaaacact tctagcgcaa
    11401 aatggtttgt atgcagatat gtacaaactg caaagcagtg gtgtgtaaaa agaggttgtg
    11461 acagtagcat agtagcattt tgccctaagc gctagagtga aaataaaaca gagcttcgca
    11521 gattcttcat ctgtgagcgt tagtggcgta gtcacccgat ttaaaaaaga cgacgacagc
    11581 tagtcaaaag cggctaataa ccactaagaa agcgttgaca aaagcgtttg ctttcgataa
    11641 tataaagaaa acgatacaac ttggatagtg attgcctgat gcaagctaaa cctgatgagt
    11701 ctcccatggt tccatggacg gctttttggg tttttctttt tgttttggat acagccctat
    11761 atatcatgga aaggagcaaa acatgctgat tgagaaagta ctgaataaca acgtcgtaat
    11821 aaccagggat gaaagaaatc aggaaatgat cgtgatggga aaaggtttgg cattcaaaaa
    11881 gaaagtgggt gacccgattt ttgactcatg catcgacaaa aaatttcagt tgacaaatga
    11941 cgggctttca caacagttcc aagaattggc acaagcgatt cctcttgagt acttagaaat
    12001 ttcttgtgaa atcattgaat atacaaaaga ggctctacaa gtccagttga atgattctgt
    12061 gtatattgca ttgacggatc atttgtatac ggctatcgaa cgtcacaaaa tgggaatatt
    12121 tgtaccaaat gtattgctgt atgatatcaa acaactattt cctaaagagt atgccatcgg
    12181 gaaaaaaaac agtgaagaaa atctcggata aataccacat caagttatca gaagatgaag
    12241 ccggatttat cgcattgcat ttagtcaatg cacaaggcat tcaaagccaa caagacaata
    12301 cctacctgtt cactataaca atacaggata ttctaaatat cgtccgctat tactataaga
    12361 ttacatttga tgaagattca gtccattttt ttcgattcgt cacacactta cgtttttttc
    12421 tgacacgcgt cctagatgga gaaaaatcag aagtgggaga agtttctgag gaattgtttc
    12481 aggttattca aaaaaaatat aaggatacgt ttggttgcgt tgagaaaata gcagactttt
    12541 tagccgagac gttcaactac cagatgtcca cggacgaaaa aatgtattta acgatccata
    12601 ctgcgcgttt agtgcatgag aatcgttgta aataaataaa aaaaggagga taaattaaca
    12661 agaacgtatg aaataagggt agtgacattc agttggctaa accttccact aataaattgg
    12721 agggaataga aatgggaaaa taccaagaat tagcgagaaa aatcgtagaa aatgtcggcg
    12781 ggaaggaaaa tatcaatggt ttgacacatt gtatcacaag gcttcgtttc aaattaaaaa
    12841 acgaagaaaa agcaaatgat gagatcttga aaaatatgga cggtattgta acggtaatgc
    12901 gagcgggagg gcagtatcaa gttgtcatcg ggaatcatgt gccagtcgtg tttgaagagg
    12961 ttataaaagc aggaaacctt acttttgatg aggctgtttc aacagaaaaa atgagaccgt
    13021 ttgatatgct tattgatgga atatcgggct gtttccaacc attccttgct atcctagctg
    13081 ctgacgggat gattcgtgga ctgacagcat tccttgtctt cttaggcgcg tttgaccgcg
    13141 gttctggcac atttgttatg tttgataata tcggtgattc tgtattccaa tttatgcctg
    13201 ttattatcgg tttaacagct gcccgtaaat ttaaagtaaa tgaattcgta gggatgttgc
    13261 ttggcgcagc attaatgaat cctagcttgt cgctggaagc tttgagtggt gcagcagaag
    13321 caccactaac gaccatattt tctggcacta tttttgaagc acctatttat caaacagtat
    13381 tcggcattcc ctggattgcg cgtaactacg cttcttctgt cattcccatt atctttattg
    13441 tgttgttagc tagccaaatt cagaaaccaa ttaaaaagtt agtacctgag atgatcgcga
    13501 atttcttcgt tccattcttc accgttctta ttacaatgcc tttaggtttt ttactcgttg
    13561 gaccagtatt cacattcgca actgatattt taatggctgg atttgaaaca cttttagcac
    13621 tttcgccagt tatttatgga gcaatcgtag gcttcttctg gcaaattctg gtgatgtttg
    13681 gtctccattg ggcaatcgta ccaatgggat tgatgcaatt ttctgtgaat ggttggcaaa
    13741 atattatgac acctgttgca gtagtgtctt ttggacaaac tgcagcactt accgcactct
    13801 actttaagct tagaaatcca aaagacaaag caattgcaat accagccatt gtttctggta
    13861 ttgtggggat tacagagcca gctatttatg ggtttacatt gccacgtaaa aaaatattta
    13921 tttttacctg tgtcggtggt gcgttagggg gcgcgtatag tgggttaatg aatttaactt
    13981 cttggaatca aggtggacta ggcatcttta caattcccaa ctatattaga ccagatggtg
    14041 atttaacaga tgtgattaat gtattgattg ggatcgccat tgcgatggtg gtatcctttg
    14101 cgctgacttt tttcttttgg aaggaggaag cagatgaaac agatgataga cagaaaagat
    14161 caggtaaaga aattgtaaaa acaccgatac aaggacaaat cgctccactg aatgcagcaa
    14221 aggatgcagc ttttgcacaa ggaacactag gtcgaggaat cttgatctac cctgaaaaag
    14281 gagaagtacg tgcccctttt gacggaacag tcatgtccct gtttccgacg aaacatgcaa
    14341 tcgggatggt ttctgaagca ggtctggaat tgctgattca tgtcggattg gatactgttc
    14401 agttggaagg gaaatatttt gaaagcttgg tgcagcaagg agaaagagtg aaacaaggcg
    14461 atctgttgct tcgcttcgac aaaaagaaaa tcgaagagga aggatacagt ttagaaacac
    14521 ctgtgattgt catcaattac atggattatt tggatatttt ggaaaatcaa ggggaaacgg
    14581 tcgggccaga cgatgcactt atcaccgcac tgacctgaac ggttaggtga aagaatggac
    14641 taggcttaac tattcttttt agtccacttc tttattttca aaattgaaag gctctttcat
    14701 gatggctgag ctgatagggc gtttatcaaa tttttgtcct acagaaatta gatggactaa
    14761 attctgttga taattttctg caaaaacaca actatataac acgtctagaa gataacaaat
    14821 cgatgtattg atcgtaaaat taccaatttt cgaatacagt cgttcgcgtg tcgtaagtcg
    14881 caaagcggct gtactcattg aagatagcgt tgaatcaccg atactggtca aagctaaaat
    14941 tggcacatga ttttgtttca atatttctgc ggtacgaagg atcacattgt tttcacccgt
    15001 ataagaaatc agaatcccac acatatcact tgtgcaattg tacgcttcat agaacgattc
    15061 accaaaagtg gtgacaatcg tgacatccat tttgatgcgc ttcattttca gcatgaaatc
    15121 ttgagaaatc aaagtattcg agttactggc gaaaatcacg attttttttg cttgaagcat
    15181 tagttgtttg gctttttgca gttggtcatg atgaatgaga gaaagtgtat cttgaatcgt
    15241 catctgttct aaagaagcca ttttatttgc gatcgtcata ataccgtctg tggtggaaaa
    15301 aggaagattc gcatctacgt cttgaaaatt cccttcaaga taggctgttt cagctaaaaa
    15361 agcattacga aaactgaccc agccatcaaa acccattttt tttgctacac ggatgagtgt
    15421 ggacgggtgg acataacatc gctcagcaat ctcttggatg gtcatttcgc caagtgctgg
    15481 agaatcgctt aagagaaact gaatcacttc attttctgaa ggagaaaagg agatttcttt
    15541 gattttttca cgtaataaca tgtagatacc ttcttcttgt ttttttacgt aaatcataac
    15601 ttttttgaaa atgatttgta aacggattta tgttatatag cttaataaag acattttttg
    15661 acaagatatt tacaaaaatc cagaagaaaa cactaacttt tgtaaatgtt actggaaaga
    15721 aacgaatttc tattgtttgt tttgtttaca aaaaagataa taaaagtgta aaaagtaaag
    15781 gagtgagaac atggcaaaag gaatcaaaat cgctacgatt ggtggaggca gcagttacac
    15841 ccccgagttg atggaaggat ttatcaaaag atatgaggaa ttaccgatac gagaaatctg
    15901 gctcgtagat gtagaagaag gaaaagaaaa gcttgagatc gtcagtcaga tgtctcagcg
    15961 tatgtgggat gcttctccgt atgaagtcaa aatctatgca actctggatc gggaagaagc
    16021 attgaaagat gcggattttg ttacgactca gtttcgtgtc ggtcaattag atgcacgaat
    16081 caaagacgag cggatcccta gttattatgg gatgattggg caagaaacaa atggtgctgg
    16141 cgggatattc aaagcttttc gtaccgttcc agtggttttg gcaatcgttg aagacatgaa
    16201 gcgtttatgt ccaaatgctt ggctgattaa tttcgcgaac ccaagcggga tggtgacaga
    16261 agcagttatc agatatggca aatgggataa agtgatcgga ttatgcaatg tgccagtaat
    16321 ggcgatgatg acagaaccaa caatgcttgg caagaaaaaa gaagagctga tctacaagtt
    16381 tgccggtcta aatcacttcc attggcacaa agtagcagat aataaaggaa atgaccgcac
    16441 ggcagaattg attgatcgtt tatacgatga agacaatgga ttgccgaaaa atatctttga
    16501 catcccgttt ttcaaagaac aattaaaaca aatgaacatg atcccttgtg gctaccaccg
    16561 ctattactat cgtgaagaag aaatgctgga acatgcttta gaagaatatc aaacgattgg
    16621 tacaagagcg cagcaagtga aagaaacaga agcagagctg tttgaattat acaaagatcc
    16681 agaattggat cataaacctg aacaattgca aaaacgaggt ggtgcttatt attcagatgc
    16741 tgcctgtgaa acgattgctt cgatctatgg aaataaagaa acacagatcg tggtatctac
    16801 aaagaatgat ggagctgttc ctgatctgcc ggcagattgt gtagtagaag tcactgccta
    16861 tgttggcgca caaggcgcac gaaatgtagc gtttggttcc cttcctgctg ctgaaagagg
    16921 ctggttgcaa gtaatgaaga atatggaatt gctgacgatc gaagcagccg tgactggtga
    16981 ttatggaaca gctttgcaag cgtttacgat caatccgctt atacgatcag gaaagacagc
    17041 aaaacggatc atggatgagt tgtttattgc acatcagcag tatttaccgc aattcaagga
    17101 aacaatcagc cggttaaaag cagaaggaat cgaagtccaa gatgaactgg caagagaatt
    17161 atcaagcaat acacatgtaa tggaggaagt atgatgggat tcagaaaaga ttttttatgg
    17221 ggcggagcta cagcagccaa tcaatgcgag ggcggttatg atgaaggcgg acgtgggtta
    17281 gcgaacgtag atgttgtgcc aatcggagaa gaccgttttc ctgtcattac tggaaaaaag
    17341 aaaatgtttg aatttgatga aaatcatttt tatccagcaa aaattgcgat cgatatgtat
    17401 catcattata aggaagatat tgctttattt gcagaaatgg ggttcaagac ttatcggatg
    17461 tccattgctt ggagtcgtat ttttccaatg ggcgatgaaa aagagccaaa tgaatctggg
    17521 ttgaaatttt atgaggatgt ctttaaagaa tgtcaaaagt acgggatcga gccgcttgtg
    17581 acgattacac attttgattg tccgatgcat ttgatcaaag aatatggtgc gtggcgttcc
    17641 agagaactcg ttggttttta tgaaaatctg tgccgagtca tcttcaatcg ctataaagga
    17701 cttgtcaaat attggttgac attcaatgag atcaatatga tccttcatgc accattcatg
    17761 ggcgcagggc tgtattttga agaaggagaa aatgaagaac aaatcaaata tcaagcggca
    17821 catcatgagt tggttgcaag tgccatcgca acgaagatcg ctcatgaagt agatccggag
    17881 aacaaagtag gctgtatgct ggcagcagga gcatattatc catacacttg caatcctgaa
    17941 gatgtttggg cttctagaaa gtcagatcga gaaaattatt tcttcattga tgtccagtca
    18001 cgaggagaat atcccgctta tgcattgaaa gaaatggaac gaaatggcat tcagatcaaa
    18061 atggaacctg gggatgccgc attgctgaaa gaacatactg ttgattttat ctccttttct
    18121 tattattctt ctcgagtttc gactactgac aacgaactct tggaacagac tgcaggaaat
    18181 atctttgctt ctgtcaaaaa tccatatctg gaagcaagtg aatggggttg gcaaattgat
    18241 ccattaggct tgagaataac gatgaatgat atttatgatc gttatcaaaa accactattt
    18301 attgtagaaa acggcttagg tgcagtcgat acgcccgatg agaatggtta tgtggaagat
    18361 gattatcgaa tcgactatct ggcagcacat atccaggcaa tgaaagatgc agtagaatta
    18421 gatggagtcg atctattagg ctatacgact tggggatgta ttgatttagt atcagctggt
    18481 acaggtgaga tgaagaaaag gtacggattc atttatgtcg atcgtgacaa cgaaggaaat
    18541 ggcacattag cccgttcgaa gaagaaatca ttcaactggt ataaaaaagt aattgattca
    18601 aatggagaaa atctttcgaa cgattgatca atgatttata aaagtctatt gtttttcagc
    18661 ggatttttcg agtataataa agctattcga gaaacgcaag cagaacaata gacttttttt
    18721 cgcattggct gtaaagtatg cttacttgat taagtaaagg agaatctaca tatgtatgat
    18781 gtaatcgtta ttggcgcagg gcctgctggg atgactgctg ctttatatgc ttcacgttca
    18841 aacttatccg tattgatgat cgaacaaggc gctcctggcg gccaaatgaa caatacggca
    18901 gaaatcgaaa actatcctgg tttcgattca atcatgggtc ctgatctagc ttataagatg
    18961 tatgaaggtg tttcaagatt tgggacagaa aatgcttatg gaatcgtgca agatatcaag
    19021 gatcacggca gccacaaaga agttatttgt gaagataaaa cttacgaagg aaaaacagtc
    19081 attatcgcaa caggctgtat ccaccgtaaa ttaggcgtac ctggcgagga agaatttgct
    19141 ggacgtggcg tttcttactg tgcagtttgt gatggtgcat ttttccgtaa caaacgtcta
    19201 gtagtgatcg gaggaggaga ctcagcagta gaagaagcca tctatttgac acaatttgct
    19261 tctgaagtag tcatcgtcca ccgtagagat gaattacgtg cacaaaagat catccaagac
    19321 cgtgcatttg cgaatgaaaa aatttccttt atgtgggata cagtcgttga cgaaatcgtt
    19381 ggaaatgaaa tggtagtgac aggtgtgaaa gcacgtaatg tcaaaactgg caatgagttt
    19441 gatttggcag cagacggagt attcatctat gtaggattgg atccattaac tgcaccattt
    19501 agagaagctg ggttgacgaa cgaagccggc tggattccaa cagacaacga aatgaagacg
    19561 aatataccag gcgtttttgc catcggagat gttcgtgaaa aagatttgcg acaaatcact
    19621 actgctgttg gtgatggtgg gattgctgga caacaagtgt ataaatactt ggaatcttta
    19681 gaagaaacaa ctgcataagt ttaaaaagag tgaaagaacg gtttcaattg ttcttttact
    19741 cttttttttg cgtgaaatct actgaatccg atttatgcga atacttgtaa ccgtgcttga
    19801 taaaagaatc ttttcttgat ttaagcgttt tttggtcctc atactttcat atctaataag
    19861 tgaatgctat acttattaag aaccatattt cagaaagagg tgttattttc atgtcttggg
    19921 aacaagtgta tgaacaatgg gtacatgaag aaaatttaga agaaaactta aaaaaacaat
    19981 taaatgatct gggtgaagat cctgaaaaac ttgaagatgc tttttatgca ccgttggaat
    20041 tcggtactgc aggcatgcgg ggaatcttag gacctgggat caatcgaatg aacatctata
    20101 cggtaagaca agcaacagaa ggacttgcac gtttcatgga tacacaaggt gaagaaacaa
    20161 aacgccgagg tgtcgctatc gcttatgact cacgccatca atcaccagaa tttgccatgg
    20221 aagcagccaa aacattagca catcacaata tcccttctta tgtattcgaa agtttacgtc
    20281 caacaccaga gctttctttt gcagtccgtc atttgaagac gtttgcggga atcatggtaa
    20341 ctgcatccca caatccagca gcttacaacg gatataaagt ctacggagaa gatgggggac
    20401 aaatgcctcc tgcagacgca gatgcattga cgaaatatgt ccgtgaagtc agcaatccgt
    20461 taaaagttga agtattatct gacgacgaag ctgaacatag cggattgatc acgatcatcg
    20521 gagaagaagt ggatgccgct tatctagaag aaatcaaagc agtaacgatt gatcatgaat
    20581 tggtggaaac aatgggtaaa gatttgaagc ttgtgtacac accacttcac ggaacaggaa
    20641 aaatgttggg cgaacgtgcg ttgaaacaag ctggattcga acaattcgta ctagttccag
    20701 aacaagctgt cgcagacccg gatttcacta cagtcaaatc accgaatcca gaagaacact
    20761 ctgctttcga gtatgcgatg cgacttggcg agaaagaagg cgctgactta ctgattgcaa
    20821 cggatcctga tgcagaccgt ttaggcgcag ccgttcgttt gccaaatggc tcctatgaag
    20881 tattgacagg aaaccaaatc ggagccctgt ttgctcaata tattttggaa gcacaccaat
    20941 cgcgaggcac tttacctgaa aatgcagcgg tattgaaatc aatcgtttct agcgaattgc
    21001 ctacagcaat tgcggaacac tatggggcta ccatgttcaa tgtattgaca ggattcaaat
    21061 tcattgctga aaaaattcaa caatttgaag aagatcattc ccatactttt atgttcggat
    21121 tcgaagaaag ttacggttat ttagttaaac ctttcgttcg cgacaaagac gcgattcaag
    21181 cattgctctt attagcagaa gtagcagctt actataaaaa acaaggcaaa acattgtatg
    21241 acggcttgca aacgattttt gaaacatatg gctactacgc agaaaaaacg atttctgtga
    21301 caatgagcgg acaagaaggc tctgcaaaaa tctctgcttt gatggaaaaa ttccgtgaag
    21361 aagcaccgac agaatttgcc ggagcaaaag tcatccaaac agaagacttc aaagagttga
    21421 cgagaacaga ccgtgaagga aacgtagaaa aactaacgac accgccatct gacgtattga
    21481 agtatacgct ggaagaaaat ggctggatcg ctatccgtcc ttcaggaact gagccgaaaa
    21541 tcaaatttta tatcggtgta aaaggaaact cttcagaaga cgcagctgaa aaagtagccg
    21601 cttatgaagc gattatcaaa aaaatgacag aagaataaaa aaacttgaga ctgatggaaa
    21661 aagtggtaaa ctttagaagt cagtcttttt tcaagttgga ggtgaatgga ttgccagaca
    21721 cgcaaaaaac aaaagtagag aaagtcagcc aactattcaa aatgttgagt gaccccactc
    21781 gtctcaaaat tctgctgtat ctgaaagacg gggaacaaaa tgtgacagca atcacccaag
    21841 cagtagaaat ggaacaatct gctgtatcgc atcaactgcg tttattaaga gaaaaccatg
    21901 tcgtcaagtc ccatcgtgag ggaaaagcga ttttgtatag tcttgatgat tctcacgtac
    21961 tggatatttt gaaccagacg ctcaaacatg tggaacatca ataacgatag gtgcaaatag
    22021 agacaaactg gactgtatca acgaatcttc ttcgctgaca cagtccagtt tttttaagaa
    22081 aaagacaaga aaaactgtta gtctgtttct tcggtggttt cagttccata ataactatga
    22141 tcttctaggt ctaaagcatt caaaataagt gaagctgttt cttcgataga taaagaagcg
    22201 acattgatta ctacgcagcc caatttttca taaagatcat tcgcaaaatc gagttcagct
    22261 cgtatttttt cgatatcgga ataagcagta tcaggattta atccgtaaga gcgcatccgt
    22321 tctttacgga tattgtttaa aatatctggg ttattcgtca gtcccacgat ttttttagga
    22381 tcgatctccc aaagctgttt gggaatatgt gcttgtggga tcaaaggtag attggcaacc
    22441 tttaaatttt tgttagctaa aaacaagctc aaaggcgttt tggaagttct ggatacgcct
    22501 agcaaaacga catctgcttc tagaaaccca cgaggatctt tcccgtcatc gtattttaca
    22561 gcaaattcca ttgctttgat ccgtttgaaa tagttctcat tcaataaatg aagggcgcca
    22621 ggttgccgaa tgggcttgat accagttaag cgctcgattt ctgatatcgg cggagtcatc
    22681 acatcaaaac taaataattg atgttcttca caaaaagaac gcgtcatctc gatcaattct
    22741 tgattgatca atgtgtgtag gacaagggct ttttctttta gtgcatcttg cagtgcctgc
    22801 atcaatgttt tctcatctgt cacaaatgtt ctgcggaata aattgaactc aacggtagga
    22861 tattgggcca tagtggcttg cgctaatttt gtcgcagttt ctccagcaga gtcagagatg
    22921 acaaaaaaag taatgatttc tgtagaatcg gaagacatgg ataaaacctc acttgcattt
    22981 tttttatgtt tattatacca tactctagaa tgtgtacttc gtaatcattt tgatttggag
    23041 gaataagtca tgaaaaaaca gacattgatt gaacaatcac tagaaacatt gaaaaataac
    23101 ggttttaaat atactaaaaa aagagaagca ttgttaactt atttagtgaa gcgcaatcgc
    23161 tacgtatccg ctaaagaagt ttttgactat atgaatcagg aattcaaagg agtaagttac
    23221 gatacgattt atcgaaatct ccatgatttt gcagaaatcg atttactgga agaaaccgat
    23281 ttaaatggag agatgaagtt tcgttttcat tgctgtcaag gggaaatcgg ccatcaccat
    23341 cactttatct gtacggtgtg cggaacaacg aaagaaatcc atatgtgtcc aatgaattat
    23401 ttcgaagaac agctcggtgg atgtacgatc gaagggcata gattcgagat tttcggaaga
    23461 tgtgaaaatt gtcaataagg atttaaataa aataacattt gataatttta aaaaaaagca
    23521 agatttcctt gacggtcaaa acagcattag atataatatt tacaggacag tcttgttttt
    23581 tgagatatat ttcaataaca attacggtta ctttttaagc tcggagggag ggaattaaca
    23641 tgtcaaaaac agtcgttcgc aaaaacgaat cacttgacga tgctcttcgt cgcttcaaac
    23701 gttccgtgtc aaaagcgggt actttacaag aatctcgtaa acgtgaattc tacgaaaaac
    23761 caagtgtaag acgcaagaaa aaatctgaag cagctagaaa acgcaaaaaa ttctagttct
    23821 gtgatgaatt ggagttggta gtgtgtcact actaagtaga ttaaacgatg acatgaaaac
    23881 agcgatgaaa gcgaaagata aggaatcttt acaagtcatc cgaatgatca agtcatctat
    23941 acaaaacgag cagattaaag aaggtcacga cttgacagaa gaagaagaat taacggtgtt
    24001 gtctcgcgaa atgaaacagc gacgtgattc tttgcatgag tttgaagaag caggacgtga
    24061 cgatttagct gaaaaagtaa aaagtgaaat tgtgatagtc gaaaaataca tgccggaaca
    24121 actttccgac gaagaaattc gacaacttgt tcaagaagca atcacacaaa ctggtgcttc
    24181 atcaatgaaa gaatttggca aagtcatggg tgcgatcatg cctaaagtca aaggaaaagc
    24241 agatggaaac caagtaaatg ccattgtgaa agaactatta caatcttaat tttatcattt
    24301 aaaggctctt cgtcaatgag tgttggtgaa gaaatt
//
LOCUS       DAPBBR010000041        24234 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPBBR010000041 DAPBBR010000000
VERSION     DAPBBR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.041"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(313..903)
                     /locus_tag="RD488_001849"
     CDS             complement(313..903)
                     /locus_tag="RD488_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDT7657920.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
     gene            1426..1587
                     /locus_tag="RD488_001850"
     CDS             1426..1587
                     /locus_tag="RD488_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7657921.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLA"
     gene            1606..2100
                     /locus_tag="RD488_001851"
     CDS             1606..2100
                     /locus_tag="RD488_001851"
                     /inference="COORDINATES: protein motif:HMM:NF018154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7657922.1"
                     /translation="MIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGYSF
                     ILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEMFI
                     NAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPIQYTSKELEE
                     ELHD"
     gene            2093..2254
                     /locus_tag="RD488_001852"
     CDS             2093..2254
                     /locus_tag="RD488_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657923.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            2738..3761
                     /locus_tag="RD488_001853"
                     /pseudo
     CDS             2738..3761
                     /locus_tag="RD488_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            4104..4360
                     /locus_tag="RD488_001854"
                     /pseudo
     CDS             4104..4360
                     /locus_tag="RD488_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            4747..4974
                     /locus_tag="RD488_001855"
     CDS             4747..4974
                     /locus_tag="RD488_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDT7657924.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            4990..6156
                     /locus_tag="RD488_001856"
     CDS             4990..6156
                     /locus_tag="RD488_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDT7657925.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGNRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6391..7434
                     /gene="hrcA"
                     /locus_tag="RD488_001857"
     CDS             6391..7434
                     /gene="hrcA"
                     /locus_tag="RD488_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HDT7657926.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7528..8091
                     /gene="grpE"
                     /locus_tag="RD488_001858"
     CDS             7528..8091
                     /gene="grpE"
                     /locus_tag="RD488_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDT7657927.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            8142..9971
                     /gene="dnaK"
                     /locus_tag="RD488_001859"
     CDS             8142..9971
                     /gene="dnaK"
                     /locus_tag="RD488_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDT7657928.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            10122..11288
                     /gene="dnaJ"
                     /locus_tag="RD488_001860"
     CDS             10122..11288
                     /gene="dnaJ"
                     /locus_tag="RD488_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDT7657929.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(11656..12393)
                     /locus_tag="RD488_001861"
     CDS             complement(11656..12393)
                     /locus_tag="RD488_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7657930.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(12395..13897)
                     /locus_tag="RD488_001862"
     CDS             complement(12395..13897)
                     /locus_tag="RD488_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HDT7657931.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            14156..16150
                     /gene="uvrB"
                     /locus_tag="RD488_001863"
     CDS             14156..16150
                     /gene="uvrB"
                     /locus_tag="RD488_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDT7657932.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            16160..18976
                     /gene="uvrA"
                     /locus_tag="RD488_001864"
     CDS             16160..18976
                     /gene="uvrA"
                     /locus_tag="RD488_001864"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDT7657933.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            19239..20504
                     /locus_tag="RD488_001865"
     CDS             19239..20504
                     /locus_tag="RD488_001865"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HDT7657934.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            20508..21239
                     /locus_tag="RD488_001866"
     CDS             20508..21239
                     /locus_tag="RD488_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HDT7657935.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            21374..22258
                     /gene="rapZ"
                     /locus_tag="RD488_001867"
     CDS             21374..22258
                     /gene="rapZ"
                     /locus_tag="RD488_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDT7657936.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            22255..23253
                     /locus_tag="RD488_001868"
     CDS             22255..23253
                     /locus_tag="RD488_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDT7657937.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            23287..24222
                     /gene="whiA"
                     /locus_tag="RD488_001869"
     CDS             23287..24222
                     /gene="whiA"
                     /locus_tag="RD488_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDT7657938.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
BASE COUNT         8145 a         4092 c         5122 g         6875 t
ORIGIN      
        1 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
       61 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      121 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac
      181 tgttgccatt ccatctatga atataaatag agtgtatctt ctttgataaa tgtcagaaaa
      241 agtgtgacaa ataaccatca gtaaaattac ttgtcatact attgataagg agtatttaat
      301 tgaagagaat gattaggaga aaggatctcc gtacttttta tagtaatcat agaatccaag
      361 tttgtataga cgaatctttt tttctcttat ttcttctgtt tcaaaatgga ctgcttgaag
      421 aatcaagtct gtgaattcta taggagctgt tccattcgca gtaatcaaat tacgatcttt
      481 cacagcttgt tgttctataa aatcttcttt attctgataa ttttccgatt ctaaccaagg
      541 aaattgcgca tttccggtgt gtttgtaacc ttgcaataat ccgctctgag ctaaataatc
      601 aactgcccca caaatagcag ctactggtac gtctgttttt aacaatttat cgattatttg
      661 atataaatga tgatttttta tgtcccatga attgccaccg atcataataa aaaggtcaac
      721 tttttcaggt atttgttcga ttaagtaatc gatttttgtt tttaatcctc caatggaagt
      781 gacctctgat tggatagaag cagttttgtt ttgccatccc tctttttggt ttagtgtgct
      841 agtaatataa gcaccttccc aatcggcata ttcctctaat agaaacgtaa tcgcagtttt
      901 cattttcaag ctctccttta ctatctatga caaggacaac agttttaaca tacagacatt
      961 cattaaattt ggatagcgac agcgaaaaca acaattctta agttttagac agagtataca
     1021 gacagtcaac ttaattaaat acgaactaaa taaaaatgac aggtaatcat ttttgtttac
     1081 cagcattata acattttgca tacatggatg acaaaagaac caattcccac ttgcttgagt
     1141 acaatcttaa aagaaactgg aaggcaaaaa gtaattatag aaacgaaaaa taaatcatat
     1201 cgggcactca gacatgaaaa caaccctaga aatatataac tagtccaatg aaaaaaaagc
     1261 gaatgccgta gaaaacaagg attctgcgta cattcatatc tcattttgcg agcatatctg
     1321 ctattactgt gactaaatgt taatatggtt aaaatgaccg ttatattttt tatataaata
     1381 tcgtataatt agtatgaata tagaagaagg aaagaaggtg caatcttgga acctaaagac
     1441 aagtatttag attacgctag ggtcaataaa gataaattta ttgaaacaat catcaaggga
     1501 aaaatccctg atgatgaaaa agatgcggta ttcatggctg gaagcccagg agcaggtaaa
     1561 acagaggttg cactaggttt agcttaaaat tatgacaacc atgttgtgat tgatgcggac
     1621 tattttagag cacaatttcc agaatacaat ggaaagaact caagtgtttt tcagaaagct
     1681 tcttcttggt tagttgaaca atcattaaaa tatgtactgg aacatggcta ttctttcata
     1741 ctagaggata cttttgctat ccttagtgca gagaaaaata ttattcgagc ccttaaaaat
     1801 aactttcgcg ttacgatttt ctatgtttac caagatccca aagttgcctg ggatttcact
     1861 cgaaaacgtg aactagctga aggacgtcat gtgccaaaag aaatgtttat caatgcgttt
     1921 tttaagtcca gagagaatat tgaaaaagtc aaaaatagac atcctgaagt agtccttcac
     1981 ataatgatta aggattatca aaacgacatt tctgaagtgc attatgcagc agataatatt
     2041 caattagtac taccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     2101 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     2161 aaacgcctca gcgaaagaat ttaaaacagt aatgaattac gtagcagatg aagcaaatcg
     2221 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     2281 ttgagttttt tattttaatg aattaagact attaaataga taattattgt aacttaaaaa
     2341 acacagctaa aaattagttg tgttttttat taggtttact tttctggtat aaaaggaact
     2401 agctactttt tcaaaatttc taaatcattc aatatgtagc gcttactaaa ttattcgcca
     2461 taaaatttta taattggatc actcattgtt ttacctaagt catatttaag taataaccgg
     2521 tgtttttaca taagaagact tcgggtattt tttagtttga ttagctctga tatacctata
     2581 aagaatatgc taaggtaaga atagtaaaaa ttcacataga tgaggtataa taatgatatt
     2641 tttatatatt acagataact tgacacaaaa tgagtttttt tcgatttttc aagttatcta
     2701 atgcaattat attgatatca ttaggagctg cattgttatg aatccaacat tgattactaa
     2761 gaaagaatta ctaaaaaaat tagatatttc tactggtgta ttagctaatt taattagaaa
     2821 tggcatgcca aaagagggag aaatgtttaa tcttgataag attattacat ggcgagaaaa
     2881 ttggtctaaa aacatattag gtgagttaga agttggtaga gtatatacta acaaagaaat
     2941 ttcagagaag tttaaatgtt ccaaacaggg tggaatgaga agatctcatc aaactaatac
     3001 tcttgtactg tttagtgatc aaacaggaag taatgtttat aaagataagt ggttaaatgg
     3061 tattttacaa tataccggta tggggctaaa aggggatcaa gtattggata agaatcaaaa
     3121 taaagtttta gccaattcaa aaagtaattt tgtaaagatt catttatttg aaacatttaa
     3181 accaaaagaa cacacatatc tgggagaagt atatttagca ggacaaatat atactgttaa
     3241 tgaaaaagat agttcgggca acagcagaaa agtatataaa tttccattag ctttaataaa
     3301 tcaagagcaa ttgattgaag ataaagatat ataaccagga agaaaatcaa actagacata
     3361 ttcgtaattt atctaatgct aaattagagg aagaagcaag aaaagttagt aattataata
     3421 aaaaaatggc tgcaaaatat gttaacgaag aggagttttg cttctcaaaa acaaaaatat
     3481 ataaacgtaa tcccttcgta tctgaatatg ttaaacgact tgcaaaaggt atttgtcaac
     3541 tttgccaaga aaaagggcca tttataaaag acggtgtacc ttatttacat tgtcatcata
     3601 tagaatattt gtcgcaaggt ggaaaagatg tgattgaaaa ctgtatcgcg ttatgtccca
     3661 attgtcatgc tagaattcat gaacttgagt tacctgacga taaagaaaaa ttgctgaaga
     3721 tcgttgaaaa aagagaaaat agcttttcta aaataccgta atttattttt ataggacaaa
     3781 taagctaatg tgagctatgc cttctatata agactaagtt ctattataag taacgaagta
     3841 attctcgttc cttcctgtag taatattttt taaataacct ataggcttct tcaaaagtac
     3901 atcctccagt aaattctaag tactggagga ttctttttct agtgttgctt tactcatgaa
     3961 aaagtagttg gctacttcat caaaatttct gaactttttt aatgtataat aaagagctcg
     4021 atcatttact acaaggatgc tagctcctac attttcacag ttttttagca agtaaatttt
     4081 tctaaaatca catcaggaaa tgcatgagat tctttaagag aggcaattat agggctatga
     4141 ttacggttcg tgtaagtgac gccaaaaaag aatggctttc ttatatggct gaattttatg
     4201 ggattacttt atctgaactt ctaaaaaact attcgatgga acaactagaa gatgaataca
     4261 atcgtcaaac ggctgaaatt gcccataaac attggataag aagtgggaaa acaacagtat
     4321 tcatggaaga atccttaatg aatttggtgg gctggaatga cctgccgttt aaaattcacg
     4381 cccgaaattc agaagcagct ctgattggca aatacgtgta ttggtagaga tagaagataa
     4441 tcaattcgtt gttatcgcta ttcaagtagg gcaccgaaga aatgtctatg attaagagac
     4501 tgtttatttt tacaaaaaaa taataattgg aatctagtta aaactcttga agtgagagat
     4561 ttgactagat ttttttatga ataaaataag gacaaaattg tttaggaaga atcatgagtg
     4621 taaaaaaatc atccaagaag tcgattcttg gattttttag tggatttgtt cgccaaatac
     4681 gtttagtatg cgtatatgag aggttgtaag caaagcgttg tggtctgagc acttaaggag
     4741 gaatctgtga aaatagcttt tcatattttt gcagattttg acttaatgcc gaaggtcagc
     4801 tttgcgatta ccgtttatcg agaggctgta aaagcaccgt gtagctccga tgacaataag
     4861 caagcatttt tagagctagg tttccttgat tctaaatatg cggcttattt caatgagttg
     4921 gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg acttttcgac gtaaggagaa
     4981 agaatttcaa tgatagaaac aataaatccc gcagaaaaca aggtttctgc gtacattcat
     5041 atcccatttt gcgagcatat ctgctattac tgtgacttta ataaagtttt tttagaaggg
     5101 cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa tgagattaat gctggaaagt
     5161 catcctacag cgaatttgga aacactttat gtaggaggcg gaacaccaac ttctttatct
     5221 gctaaacaac ttgatcgact attatcaggt gctagagaga tcctgccttt tcaaaatggt
     5281 aatgagttta ctgtagaagc gaatcctggt gatttgaccc gtgaaaaact tcaagtgatg
     5341 aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga catttgacaa tcgcttattg
     5401 aaaaaaattg gacgtaaaca tactgcagaa gatgtgtatc aaacaatgca atttttagaa
     5461 gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg cattaccggg acaaacacta
     5521 gaaggaaatc gggatacttt ggaaaaagct ttggctttgg atctgcctca ctattctttg
     5581 tactcattga tcctcgaaaa caaaacaatg ttcatgaact gggtacgaca aggaagactc
     5641 gaactgcctg atcaggaaac ggaaaccaga atgtttgaag agacgattga agcaatggaa
     5701 aagcatggac gtcaccaata tgaaataagt aactttgggc tctccggaca tgaatctcaa
     5761 cataacctca tgtactggaa caatgaccac tattttgggt ttggagctgg tgctagcggt
     5821 tatcttggag atattcgtta ccgcaacaaa ggaccaatcc aacactattt acgcccatta
     5881 cgagcaaatg aacgcccggt attggaagaa gaaaaattga cacgaaaaaa tcaaatagaa
     5941 gaagaaatgt tcttaggact aagaaaaaaa acagggatta ctaaaaaaca tttctatgat
     6001 cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc taagggaatt agagcaagaa
     6061 gggttacttg ttaatgaaga agaccgtgtt tatttgacac caagagggac ttttttgggg
     6121 aacaatgtgt ttgagcgctt tttatttgaa aaatagtttg aagaatattt gttttttatc
     6181 gaaacttgaa aagaaaaagt ttagaaagtt tgacaatgag gtattgaagt attgatataa
     6241 ctggatttac atcaattatt tagaattagc actcttgtgt ttagagtgct aaaaaatgga
     6301 gtctttctct tgacaggaga agggcttctt gctatattta taagtgaatt agcacttaga
     6361 atatatgagt gctaatgaga ggtgaggaag atgttaacaa agcgacaaaa cgacatttta
     6421 cgtctgatca tccaacacta tacgagtagt ggcgtgcccg ttggttccaa aacattaatg
     6481 tctgagggag tcaaggccag ctcagcaacg attcgcaatg atatgaaagc attagaagat
     6541 gaaggattgc tgttgaagac tcactcttct tctgggcgga ttccatctgc tttaggctat
     6601 cgttattacg tggatcattt gttaaaacct gctcgcgtag cagaagatga tttgctgctg
     6661 attcgtcagt ctctaggcag agaatttcat gaaatcaatg agattattaa gcaatctgct
     6721 gagatattat ctgagctgac aagctatacg actttttcat tgggacctga aataaaagac
     6781 cgccgactga ctggctttcg tatcgtaccc ttgaataatc gacagattat tgctatcgtc
     6841 gtaacagata tggggaatgt agaaagccaa gtgttcactc ttcccgaata tatgggaagt
     6901 caggaactag aaaaaatggt acagattgta aacgaccgtc tagtcggaga tcctctgatg
     6961 acggtgtacc ataaacttcg tacggagatt ccgatgattc ttcataaata tttccagacg
     7021 acagaaggga tgtctcagtt atttgacacc gttcttggtc atgtttttga agaaaaggtt
     7081 tatgtcagtg gacaaatgaa tctcttggat tatgagcccc gtcaagatct tgatcagttc
     7141 aaatcgatgt tttcttttat gaaagactca gacggactta cacaaatgat cactccgatg
     7201 gatagcaata ttcatatcaa gattggtgct gaattaggca atgatttatt gcagaatatg
     7261 agtatgattc aagcaagtta cgagatagat ggtcatggaa gaggtacaat agccttgtta
     7321 gggcctacta gtatgcctta ttctcggatg ttcggtctag tcgatgttta tcgaagagaa
     7381 ctagcagcta aacttgctga ttactaccgc tcgcttgact tgtcaaactc gtaatgtgaa
     7441 taacgaagct atttgcagct gatcgttctc tctttcttag taagagcaat caaacagctg
     7501 actgaataat gaaaggaaga ctgtatcgtg aaagaaaatc aagaagaact agataaagaa
     7561 atgacagatg ctcagccaga accggaaatc gatgtcgaag ctgcagaaga ttcgggtatt
     7621 tcagaagctg aagcggaaga attcgaaaca gcgaaattaa aagctgagtt agaagaaatg
     7681 gaagataaat acttgcgggc tcgtgctgaa atcgcaaata tggcaaatcg aggaaaaaat
     7741 gagcgtgagc aattacaaaa ataccgttca caagatttag ccaaaaaatt acttccatca
     7801 attgacaacc tggaacgtgc attagccaca gaagtgtcag atgatcaagg ggcaggtttg
     7861 aaaaaaggcg tggaaatggt cttggaaagt ttgcgtaacg cactggaaga agaaggaatt
     7921 gaaaaaatcc ctgctaaagg agaagccttt gatcctaatc ttcatcaagc agtacaaact
     7981 gttccagcga ctgaagatac accagccgat acgattgtag aagtactaca agaaggctac
     8041 aaattacatg atcgcgtgtt aagaccaact atggtcattg ttgcacaata attgtgcgga
     8101 tataaaactt acactttcaa ttaaagaagg agacgttaat tatgagtaaa attatcggta
     8161 ttgacttagg tacgactaac tctgcagtag cagtattgga aggaaacgaa gcaaaaatca
     8221 tcgctaaccc agaaggaaac cgtacaacac cttctgttgt atcattcaaa aatggagaaa
     8281 tccaagtagg ggaagttgca aaacgtcaag ctgtgacaaa cccaaatacg atttcatcaa
     8341 tcaaacgcca tatcggtgaa gcaggttaca aagtagatgt agaaggtaaa tcatatacac
     8401 cacaagaaat ctcagcaatg atccttcaat atatcaaagg attcgcagaa gactatttag
     8461 gtgaaaaagt cgaaaaagca gttatcactg tgccagctta ctttaatgat gcacaacgtc
     8521 aagcaacaaa agatgctggt aagatcgctg gtctagaagt agaacgtatc gtcaatgaac
     8581 caactgcagc tgctcttgcc tatggtttag ataaaacaga tcgcgacgaa aaaatcttag
     8641 tattcgacct tggtggcggt acttttgacg tatctatcct tgaactagga gacggtgtct
     8701 ttgatgtatt gtcaacagct ggcgacaacc atctaggtgg ggacgacttt gataacaaaa
     8761 tcatcgacta catggtagca gaattcaaaa aagaaaacag cattgacttg tctcaagaca
     8821 aaatggcttt acaacgcttg aaagacgctg ctgaaaaagc gaaaaaagat ttatctggcg
     8881 tatcaagcac acaaatcagc ttgccattta tcacagcagg agaatctgga ccattgcatt
     8941 tggaaatgac attgacacgt gcaaaatttg atgaattaac agctgactta gtagaacgta
     9001 caaaagtacc agtacgtcaa gcgttaaaag atgcaggtct gtcacaatca gaaatcgacg
     9061 aagttatttt agtcggtgga tctactcgta tccctgcagt tgtagaagca gtacgtaaag
     9121 aaacaggaaa agaaccaaac aaatcagtta accctgatga agtagttgct atgggtgctg
     9181 ctatccaagg tggcgtgatc actggtgatg tgaaagatgt tgttttactt gacgttacac
     9241 cattgtcatt aggtatcgaa acaatgggtg gagtgttcac taaattgatt gaccgcaata
     9301 caacgattcc aacaagtaaa tcacaagtat tctcaactgc ggcagataat caaccagcag
     9361 tagacatcca tgtattacaa ggtgaacgcc caatggctgc tgacaacaaa actctaggaa
     9421 gattccaatt gacagatatt ccagcagctc ctcgtggtat tccacaaatc gaagtaacat
     9481 tcgatattga taaaaacggg attgtaaatg tatctgcgaa agatctaggt acacaaaaag
     9541 aacaaaaaat cacgatcaaa tcttcttcag gtctaacaga cgaagaaatc gaacgtatgg
     9601 tgaaagatgc agaagcaaac gctgaagcag ataaagctcg taaagaggaa gttgacctac
     9661 gtaatgatgt agacgcattg ctattctctg tggacaaaac attgaaagaa ttagaaggca
     9721 aagtggacga agaagaagtg aaaaaagcag aaacagctcg tgacgaatta aaagccgctg
     9781 ttgaagcaaa caacatcgag gaaatgaaaa ctaaacgcga tgcattgaac gaaatcgttc
     9841 aaaacttgac tgttaaacta tacgaacaag ctgcacaaca acaagctcaa gaaaatccag
     9901 aagcagctca aggcggagca gatgatgtcg ttgatgctga ttttgaagaa gtcgatggcg
     9961 acgataaata atcagttcac tgaatttcga gagaaggcca aagttgctac tttggctttt
    10021 tcttttgaaa aatagtttga agtatcggtt tttgtttcaa acaaaatatg atatgataac
    10081 aagcgacgtg aaaatgatga gaaccaatag gaggaaagcc tatggcaaca aaacgtgatt
    10141 attatgaagt cttagggctc tcaaaaggag catcagaaga tgaaataaag aaagcttatc
    10201 gtaagctttc gaaaaaatac catcctgaca tcaataaaga acctgatgcg gaagaaaaat
    10261 tcaaagaagt atcagaagca tatgagattt taagtgaccc gcaaaaacgc gctgcatacg
    10321 accaatacgg gcatgcaggc acagatccaa attacggtgc tggtggagct ggtggcggat
    10381 ttggtggatt cggcggcttc tctggtggcg gcttcggtgg ttttgaagat atcttcgact
    10441 ctttctttgg aggaggcggt cggtcagtcg atccaaatgc gcctcgtcaa ggtgctgatt
    10501 tgcaatatac ggtcgacttg tcttttgaag aagcgatttt tggtgtagaa aaagaaatca
    10561 agtataatcg ggaagaaatc tgtcatactt gtggtggaaa cggtgcaaaa ccaggcacac
    10621 aaccaactac ttgtcataaa tgtcatggtg caggtacgat caatgtagaa cgccaaacgc
    10681 cacttggacg agtgatgagc cgtcaaactt gtgatgtttg tcatggcaca gggaaagaaa
    10741 tcaaagaacc ttgtccaacc tgtcatggct caggacatga gaagaaagca cattcagtta
    10801 aagtgaatgt accagctggt gtagaagaag gacaacaaat gcgtttagct ggtcaaggag
    10861 aagctggaga aaacggcgga ccatttggtg atttgtatgt ggtttttcgt gtagaagaaa
    10921 gtgatatctt tgatcgtgaa ggttctgaaa tttactatga attgccttta agttttgtac
    10981 aagcagcttt gggggatgaa gtccaagtac caactgtcca tggagatgtg aaattgaaga
    11041 tccctgctgg aacacagaca ggtacgaact tccgtttacg tggaaaaggc gctccgaagt
    11101 tacgtggtgg tgcaacaggc gaccaacatg tcaaagtaaa actgatcaca ccgaaaaatc
    11161 taaatgaaca acaaagagaa gcattacgtg cattcgctga agctggcggc atcaaagttg
    11221 aagaacagca agaagacggt ttcttcgata agtttaaaga tgcttttggc gggaaaaagc
    11281 ggaagtagtt tttctagtaa aaatataaag tagacttgcc caaattttct atttctagta
    11341 aaaacgctaa gtcattaata attaaaaacc agacgaacaa tcatacgttc gcctggtttt
    11401 tttgtagttg tcatgtttgt accaacaaaa aagccagctt tagaataaga taatcatcat
    11461 agtttctgaa ggtggtatcg actatgtact tgatatcgtc aatgaaccga tggtactttc
    11521 ttatgcgatg gaacaggtag agcgattgct tgtttgtgca ggagaacaag cgatgcggct
    11581 ggtacagtta agtgaaaaaa caagaaacta aaaatgcccg gtcgtcatga agcgaccggg
    11641 catttttggt ttttattaaa tatttaatac tttattcaag aaatcttttg tccgttcatt
    11701 ttgcggattt tcaaagattt gttgaggcgt tccgtcttct aaaaagtttc cgtcgtcaat
    11761 gaacatgaca cgattggcca cttctttagc gaagcccatt tcgtgcgtaa cgataaccat
    11821 cgtcatacct tgttctgcta actttttcat gacgttcaag acatcaccga ccatttcggg
    11881 gtcgagtgca gatgtaggct catcaaaaag catgatgtca gggttcatcg ctagagcacg
    11941 agcaatagcc acacgctgct tttgtccacc ggaaagcatt tcaggataca tatctttttt
    12001 atcttctaga ccaactgtct gcagcaattt gattgctttt ttctctgctt cttctctaga
    12061 ttctttcttc aggtccatcg gtgctaaaat gatgttttcc aaaatagaaa gatgagggaa
    12121 taggttaaag tgctggaata ccattccgat atgttgtctc accaagttga tatctgtgct
    12181 tttatccatc aagtgggcgc cgtcaataat aatttcaccg tcagaaggtt cttctaaacg
    12241 attcaagcaa cgcaaaaatg tactttttcc tgaacctgaa gggccaatga tacagacgac
    12301 atctccttcg ttgatggaca cattgatgtc gtttaatact gtgttatcgc cgtatttttt
    12361 gactaaatgc tcaactaaga ttttttctgc catcttactt caccttcttt tctaaaactt
    12421 ttgctaattt tgtcaatgct gtgatcaaaa tcaagtacat gatcgcaatg atcaagtaaa
    12481 catacgtact ttgtgttgta cgtgcaacaa tgatcttacc agtttgcagc aattcgacta
    12541 caccgattgc ggaaatgatc gttgtgtctt ttaatgagat aacgaactga ttgacgaatg
    12601 atgggatcat gatgcgtatc gcttgcggca aaatgatttt ttgcattgtc cgattataag
    12661 aaagacctaa acttctggaa gcttccattt gtccgacagg aacggcgttg atcccgcctc
    12721 gaacaatctc tgcgatataa gcacttgcgt taagagtcaa ggtgataaca ccagcaagga
    12781 agtcaggaat cgtaaatcca acgataccag gcaacccaaa gaaaataaag aacgcaagaa
    12841 ccatcattgg aattcctcgg atgatatcga cataaatact agcaattgtg cgaagagcgc
    12901 gtattggtgc tacactgaat aatccaaaaa tcacaccgat tactatagcc aaagcaaagg
    12961 agatcaaagt taggagaatt gttctccaaa gtcctttcaa caatgcttga tagttgtttt
    13021 ggataagtcc aagaaatgtt gattcatcag cagtggaaga ctcactggaa gtttctgaac
    13081 catccgctac atattcttta ataatcttat cgtattcgcc tgttcttttt aattctttca
    13141 atccttcatt gaacatatta agaagctcag gattttgtcc ttttttaacg gcaaatgcat
    13201 attttccgcc agattctttt ttgatcggtg tttccaattc ttgtccttgt ttgatcgcat
    13261 aaccgattac cggataatca tccatcattg catcgattgc gccaactttt aacccgtcgt
    13321 acaattgatc agcagcatca aaatatttga tagaatagcc atattcagat tcatggtcgc
    13381 ttaaaaattc agcactttcg gtaccaactt ttgctccgac tgtttttcct ttcaaatctt
    13441 cataagactt gatcgaagta tctccttttt tgacagctaa ttggatcccg ctatcaaagt
    13501 aagaatcaga aaaatcatag cttttctttc gttcatctgt tacagtcatt ccggcaatca
    13561 ttccgtctgc ttgtcctgat tccaaagctt gcaaagcagc agagaaacca cggtagtcca
    13621 ttcggatgtt aaatccttgc agtttggcga tgttttccat caattttaca tcgatgcctt
    13681 cgtactcgcc ctttgcgttt tgaaattcaa atggagcaaa agcagagtca ctggcaatta
    13741 cgtatacgtc ttttttgggc tctatttttt gcattgtctc gcttgtgctt gactctgccg
    13801 ttgtagtgtt gtcagcttgt gcaacatgtc caaacgcaag tgtcacaagt cctgtcatta
    13861 agaaaacaaa tgagtgaaat aaatgctttc ttttcataat caacctccta aatttccaat
    13921 attttattat tataggcgaa aagtgctgaa tcagacaaga ctgtaagctc gaaaaaatga
    13981 aaaaaatgcg agtttctaac attttatgtt ataaaacgta acatgcataa taagataaaa
    14041 aagtggcgaa agtatgttcg gtgtggtata attttttagt aaggaatgcc tttgctttcc
    14101 ttttcttttt attggtcgta aaatgaaaag gaatgaatga aaaggaggac gaagaatgat
    14161 tgagagagat acctcccgac actttgagct tgtctcgaaa taccaaccgg ctggtgatca
    14221 gcctgaagcg attaaccaat tagtggatgg cgtagtcggc gggaaaaaag cacaaatctt
    14281 attaggtgcg actggaacag ggaaaacata tacgatttcc aatcttattg agaaagtgaa
    14341 taaaccaaca ctaattattg cccataacaa aacattggct ggtcagctgt acggggaatt
    14401 caaggaattt ttccctaaca atgctgttga atattttgtt tcttattatg attattatca
    14461 gcctgaagct tatgtgcctt caagcgatac gtatatcgaa aaagattcaa gtgtaaatga
    14521 tgagatcgac aaattacgac attcggctac tagttcatta ttagaaagaa atgatgtgat
    14581 cgtcattgca tccgtttcat gtatttttgg attaggttcg ccttttgagt accaaaaaca
    14641 agtagtttcg attcgacagg gagcagaact agatcgcaat cagttgattc gtgacttagt
    14701 cagtatccaa ttcgaaagaa atgatataga ttttcagcgc ggtcgttttc gagtgcgcgg
    14761 tgatgtcgtg gagatttttc cggcttcaag agatgaacgt gccttacgtg tggagttttt
    14821 tggagatgag gtcgaacgta tccgagaagt caatgcactg acaggtgaag ttttaggaga
    14881 aacggaacac gtggcaatct tcccggcgac tcactttgtg acgaatgatg aacatatgga
    14941 gcatgccgta gcgaatatca aagcggaatt agaacagcgt ttaactgtct tgcgaaatga
    15001 aaacaaactt ctggaagctc aacgtttaga acagcgaacc aattacgata ttgaaatgat
    15061 gttagaaatg ggctacacgt cgggaattga aaattattct cggcatatgg acggacgtaa
    15121 agaaggtgaa ccgccttata cgctattgga tttctttcct gaagattttt tgatcgtggc
    15181 ggacgaatcg cacgtaacca tgcctcaagt cagaggaatg tataatggtg accgagcgag
    15241 aaaacagatg ctagtagatt acggtttccg tttgccatct gctttagaca atcggccact
    15301 tcggttagaa gagtttgaaa aacatgtcaa tcagatcatt tatgtctctg cgacgccagg
    15361 accatatgaa catgaacaaa cagataccgt tatccaacaa atcatccgtc cgacagggct
    15421 gcttgaccca gtgatcgaag ttcgtccaat catgggacaa atcgatgatc tagtaggcga
    15481 aataaatgaa cgagtcgaaa aagaccagcg ggtgtttgta acgacattga cgaaaaaaat
    15541 ggcagaagac ctcacagatt atttcaaaga attagggatc aaagtcaaat atttgcatag
    15601 tgatatcaaa acgctggaac gaacagaaat cattcgagat cttcgattag gtgaatttga
    15661 tgtgttagtt ggaatcaatt tgcttcgtga aggattagac gtacctgaag tttcccttgt
    15721 tgctatcttg gatgcggata aagaaggctt tttacgtagt gaacgttcct tagtccaaac
    15781 gattggacga gctgctcgga atgaagaagg taaagtaatc atgtacgcag acaaagtaac
    15841 agattctatg cgtctagcga tggatgaaac atcaagacgc cgtacgattc agcagaagta
    15901 caatgaagaa catgggatcg ttccaaaaac gatcattaaa gaaatccgag atttgatttc
    15961 tattacgaaa gaatcggaag atgatacaaa agaagcggta caagtctcgt atgaagaaat
    16021 gacgaaagaa gaaaaagata cgttattgat gaaattagaa aaagaaatga aaaatgcggc
    16081 gaaagcattg gattttgaaa cagccgctaa tgtgcgagat atgattttag aattaaaagc
    16141 ttcaaagtag gaggacaaca tggctaacga taaaattacg attcacggtg cacgtgccca
    16201 taacttgaaa aatatagatg taacgattcc acgagataaa ttcgtggtcg ttacaggttt
    16261 gtccggttct ggaaaaagtt ccctagcatt tgatacgctg tacgctgaag ggcagcggag
    16321 atacgtagag agcctttctg cttatgctcg tcagttttta ggacaaatgg ataagccgga
    16381 cgtagatagc atcgacggat tgagtccggc gatttctatt gatcagaaaa caacaagtaa
    16441 aaatcctcgg tcgacagtag gtactgtgac ggaaatcaat gactatttac gcttgttgtt
    16501 tgcacgtgta ggacatccga tttgtcccaa cgatcatatc gagattacca gtcaatcagt
    16561 agatcaaatg gcagatcaag taatggcttt gcctgagcgc acaaagatcc aagtgttggc
    16621 accgatcgtg gtaaagaaaa aaggacaaca taaaaaaata ttcgaacgaa tccaaaaaga
    16681 gggatacgtc cgcgttcgag tcgatggtga gatctatgat ttaagtgaag tgcctgagct
    16741 ggagaaaaac aaaaaacatg atatcgcgat cgtcatcgac cggatcattg tgaaagaagg
    16801 gattcgttct cgtctatttg attctttaga ggcggctctg cgattggcag acggctatgc
    16861 tctggttgac gtgatcggtg aagaagaaat gttgtttagc gaacactatg cctgtcctta
    16921 ttgcggattt actgttggcg aactagaacc aagactgttc tcattcaatg cgccttttgg
    16981 agcttgtcca gactgtgatg gtttaggtgt caaattagaa gtcgatcaag atttagtgat
    17041 tccagataga acgaagacac ttagtcaagg tgctatcgtt ccatggaatc caatcagctc
    17101 tcagtattat cctcaaatgt tagcgcaggc ttgtgaaagt ttcggtatcg atttagatac
    17161 accattcgaa gaattaccgg aagagcatca ggatatcatc ttgaatggga cagatgatct
    17221 tttccatttc cattatgaaa atgattttgg tggcgttcgc gatgtagaaa cgactttcga
    17281 aggggtattg aagaatatcg agcgtcgtta tcatgatacg aacagtgatt tcacgcgtga
    17341 gcaaatgcgt ctttatatga cagaattaac ttgtcagaca tgtaaaggtt atcgattgaa
    17401 tccccaagct ctatctgttc aaatcaatgg aacgaatatc gggcaaacaa atgagttgtc
    17461 tattcaaaaa gcagtagatt tcttctcaaa cttaacgtta tctgaacaag agaaagtaat
    17521 tgccaaaccg attttaaaag aagtaaatga cagactttca ttcttggaaa atgtgggact
    17581 agactatcta actttgagtc gcgcttccgg aacattatct gggggagaag cgcagcgaat
    17641 cagattggct acacaaattg gatcgaatct ttctggagtt ttgtatattt tagatgaacc
    17701 atcgatcgga ttgcatcaac gcgacaacga tcgactgatt ggctcattaa agaaaatgcg
    17761 tgatcttggc aacaccctcg ttgtagtcga acatgatgaa gatacgatgt gggcagcaga
    17821 ttatctgatt gacgtcggac ctggggccgg agaacaaggc ggacaaatcg tggctgcagg
    17881 cactcctgaa gaagtagcta atgatgaaaa ttctttgaca gggaaatatc tttcagggaa
    17941 aaaatcaatc cctgtaccaa aagaacgccg taaaggtaat gggaaagcaa tcaagatcac
    18001 tggtgcttca gaaaacaatc tgaaaaatat tagtgttgaa tttccattag gagaatttgt
    18061 agcagtcaca ggtgtgtctg gttctggaaa gagtacattg gtcaatagta tcttaaagaa
    18121 atcgttagcg caaaaattaa ataagaattc tgctaagcca ggtaaattca agacaatttc
    18181 cggctacgaa agtatcgaaa agatcatcga tatcgatcaa agcccaatcg gccggacgcc
    18241 gagaagtaat ccagcgactt atacaagtgt atttgatgat atccgtgggt tatttgctca
    18301 aacgaacgag gcaaaaatgc ggggttataa gaaagggcgt tttagtttca acgtaaaagg
    18361 cggtcgttgt gaagcttgtc gcggggatgg aattattaag atcgaaatgc actttttgcc
    18421 tgatgtctat gttccttgtg aagtatgtca tggtaaacga tataattctg aaacattaga
    18481 agtgcattac aaaggaaaaa gcattgctga tattttggaa atgacagtag aggatgctgt
    18541 agaattcttc aagcacattc caaagattca tcgcaaactg caaacgattg ttgatgttgg
    18601 cttaggttat gtgacgatgg ggcaaccagc aacgacattg tccggtggtg aggcacaacg
    18661 gatgaaactt gccagtgaat tgcacaaaat ctctaatgga aagaatttct atatactaga
    18721 tgaaccaacg acaggacttc atagcgatga catcgcccgc ttgttgcatg tattacaaag
    18781 attagtagat gctggtaaca cagttttagt gattgaacac aatctagatg taatcaaaac
    18841 agcagattat atcattgatt taggaccaga aggtggagaa ggtggaggaa cgatccttgc
    18901 gactggaaca ccagaagaaa tcattaacgt aaaagaaagt tatacaggtc actatttgaa
    18961 aaaaataatg gtataaagag gatagatagc tgagatagtt aaaaaaacat aaaaaaatga
    19021 atttttgctt gttttattaa tatcagtgtt ctagaatcat tacatggtag ttctttctac
    19081 actgattggt atagataaaa acttcctata agttcaatcc gttcaaaaaa gaattgagca
    19141 atcggaggac tttcctttga ttgctttttt ctttatggta tgatattcct tgtgtagttg
    19201 gaaaagaaaa acaagagatt atgagtaagt gagagataat gatgaacagt attgaaaatg
    19261 aagaatttat ccctatatta ttaggaagcg acatgaacgt ttatggtatg gcacgttctt
    19321 ttaatgaagc atacggcaaa atctgccaag catatgcttc ggatcagtta gcccctaccc
    19381 gctacagtaa aattgtcaat gtagaagtta ttccaggatt tgataaagac cctgtattta
    19441 tcgagacgat gcttcgtttg gcaaaagaaa gatattctga taagagtaaa aaatatcttt
    19501 tgattgcttg tggtgatgga tatgcagaat tgatctccca acataaacaa gagctgtcag
    19561 aatattttat ctgtccatat attgattatt ctttatttga aaggctgatc aataaagtaa
    19621 gcttttatga agtttgtgaa gaatatgatc ttccgtatcc taaaacattg atcgtcagag
    19681 aagaaatgtt agtaaatgga catttggaac aggaattgcc ttttgaattc ccagttgctt
    19741 tgaaacctgc aaacagtgtg gagtatcttt ctgtccaatt tgaaggaaga aaaaaagctt
    19801 ttattttaga gactagagaa gagttcgatt taattttagg ccggatatac gaagccggtt
    19861 ataaaagtga aatgattgta caagatttta tcccgggtga tgatagtaat atgcgtgtgc
    19921 taaatgcgta tgtagatgaa gatcatcaag ttcggatgat gtgccttggt catccactat
    19981 tagaagatcc tacaccagca tcgattggta attacgttgt gatcatgcca gattataacg
    20041 aaaaaatcta tcaaaccatt aaggcatttt tggaaaaaat cgaatataca ggctttgcca
    20101 atttcgatat gaagtatgat cctagagatg gagaatataa attatttgaa atcaatttga
    20161 gacaaggtcg tagcagtttc tttgtgacat tgaacggctt gaatctggct cgttttgtca
    20221 cagaagatcg agtgttcaac aaaccctttg ttgaaacgac ctatggaacg aatcaatcag
    20281 ataaagcaag attatggatg ggtgtgccca aaaaaatctt tttagaatat gctcgggaaa
    20341 atgaagacaa aaaactagct gagcaaatga tcaaagaaaa tcgttacggt actactgtat
    20401 tttatgaaaa agaccgatca atcaagcgct ggttgttgat gaaatatatg ttccataact
    20461 atattccaag attcaaaaag tattttcatg tgaaagaagg ctagttcatg gagaattttt
    20521 tcagtatttt aggcggaatg ggcacgatgg cgacagaaag ttttgttcgc ttgatcaacc
    20581 accgaacgaa agctacaaaa gatcaagaat atttgaatta tgtcttattc aatcatgcaa
    20641 cagttcctga tcgtacagct tatattttag atcgatcaga agaaaatcca atgccgtttc
    20701 tgctggatga tattgagaaa caaaatttat tgcgaccaaa cttcattgtg ttgacttgta
    20761 acaccgcaca ctactttttt gaagagttac aagcggcaac ggatattcct atcttgcata
    20821 tgccaagaga agcagcaaat gaacttgtcc gtcagcatac gacagggaga gtagcgattc
    20881 taggaacaga aggaagtatg aaagctggaa tctatgaacg cgaagtcaaa aatcttggtt
    20941 tcgaaacagt gattcctgat actgcgcttc aagaaaaaat caattacctg atctatcatg
    21001 agatcaagga atcggattat ttgaatcaag agctctatta cgaaatctta gaggaagcgg
    21061 tagagcgcct aaactgtgaa aaagtcatcc taggttgcac agaattatct ttgatgcatg
    21121 aatttgctga agataatcat tacccagtga tcgatgctca atctatttta gcggatcgaa
    21181 cgatcgaacg tgcattagct gaaagaagcg aggcattgga tacagcatcg gaaaagtaaa
    21241 aaaattggat ttggggcaaa tatcctaaaa gatatttggt ccaaatcttt ttgtaaaaga
    21301 aaaagaaaac tggtaatgat acgcccggga tgatataatt ttattatgca caatgtgaga
    21361 ggggttcgta aatatgacag ataatttgca attagtcatc ataacaggta tgagtggtgc
    21421 agggaaaaca gtagctatcc aaagttttga agatatgggc tatttttgta tcgataatat
    21481 gccgcctcga ttgattccaa aattctggga attgatcaaa gaatcaggta aagtcacaaa
    21541 aatggcttta ggagtggatt tgcgttctcg ttccttcttt gaagaaatcc aaaacatgct
    21601 gatcgaaatc gaaaatacga acttcatcga cacttctatc ttatttttag atgcttcaga
    21661 cgaagaacta gtggctcgct acaaagaaac aagacgagca catccaatgg cgatggacgg
    21721 tttgatcact gaagggatac gtaaagaacg ggcgatacta gacgacttga aagcccaagc
    21781 ttccgtgatc attgatacga caacattgac accacgacaa ttacgtgaaa aaatcaatga
    21841 gtcattcaaa tcaaagggag accaaggatt tcggatcgaa tttgtatcat ttggttttaa
    21901 atacgggttg ccgatcgatt cggatattgt gatggatgtg cgttttttgc ccaaccctca
    21961 ttatatcccg gaactaagac cattgaccgg aaaagatcag ccagtctatg attatgtgat
    22021 gtcctttgat gaaacgcaat cattctacca taaatttttg gatcttctgg aaactgtatt
    22081 gcctggatac attaaagaag gaaaaagcag cttgacagtt gcaatcggct gtacaggcgg
    22141 tcaacaccgt tctgtggcat tgactgaacg tttggcaaat gctttaggga aaaactataa
    22201 agtcaatgtg acacatcggg acaaggataa aaggaaagag acggtgaacc ggtcgtgaaa
    22261 atgaaaacct accggataag aaaaccaaag atcgtagtgg tcggcggtgg cactggtctg
    22321 ccagttatcc tgaaaagttt acgaaatcaa ggagcagata tcacagcagt agtgactgtt
    22381 gcagatgatg gtggaagcag cggtgcaatc agagaatcga tcgctatggc tcctcctggt
    22441 gacttgagaa atgtcttagt ggcgttatcg gatatgccac aattctatga agatattttc
    22501 caataccgtt tcaaaaagga agatcagttt ttagccaatc atacgatcgg taatctgatc
    22561 attgccgcag tttccgagat gcggggaagc acttatgagg cgattcaatt attagcaaaa
    22621 atgatgcatg tagatggaca tgtttatcct tcttcagaaa ctcctttgac cttgcatgct
    22681 gtttttaaag acggaacgac tgcagtagga gaatctaaaa tcgcgatcaa ccgtaaaacc
    22741 attgaccgtg tgtatgtctg caacacaaat gataaaagtg aagccaaagc ggctcgaaaa
    22801 gtcgtttcag caattatgga cgccgacatg gtcgttttgg gacccggaag tttattcacc
    22861 agtatccttc caaatttagt gataccagaa atcggcgaag caatgctcaa gacaactgct
    22921 gaaaccgtct atatctgtaa tatcatgacc caaaaagggg aaacggaaca tttcacagat
    22981 gccgatcata tacgtgtttt acacaagcat ttgaatcagc cttttatcga tacagtattg
    23041 gtcaatacgg aaaaagtgcc tgaagattat atggacccag agatctatga tgagtatcta
    23101 gtacaagtcg cacacgactt caacggattg agaaatgaag gatgtcgagt gatttccacc
    23161 gactttttag aattgaaaga tggtggtgtc ttccacgatg gagacaaagt agtagaagaa
    23221 ttgttccgtt tagttttcgg ttcaaaatat taagcaattt attgttggag aaaggaggag
    23281 aataggatgt catttgctgc agatgtgaag aaagaactaa ctggtttgga agttcatcga
    23341 gaacatgcga aagcggaatt agctgctttg ctgcgaatga acggctcttt aggtattgtg
    23401 aaccagcagt ttattttgaa cgtccaaaca gaaaatgctg caattgccag acgtatctat
    23461 tctcttttga aagatcatta tcaggtacga agtgagctac tcgttcgtaa aaaaatgaaa
    23521 ttaaaaaaga acaatgtcta tatcgtccgg ttgaagcaag gcacaaaaga tgtgttgatg
    23581 gatcttgata tcatggatgg tatgatgttc aatggacacg tttcggacga gattatggga
    23641 aattcgcaaa aaatgcgttc ttacttacgt ggtgctttta tggcctcagg ttcagtcaat
    23701 aatccggaaa cgagtcgtta tcatttggaa atattttcta tttatgaaca gcataaccaa
    23761 gacatttgcg atatgttaaa ttattacggt ctacatgctc gaacgcttga acggcgcaat
    23821 ggctatattt cgtatttaaa aggagcagaa aaaattgctg atttcttaac attgattggt
    23881 gcaaccaact caatgctccg atttgaagat gttcgaatcg tacgggatat gagaaattcg
    23941 gtcaatcgtc tagtcaattg tgagacagca aatctgaaca agacgattga tgcggcttct
    24001 aaacaaatcg aaaacatcga attgatcgaa gcaaaggtcg gtctacatgc ccttcctgaa
    24061 aaacttcagg aaatcgcaga acttcggctt caacatccag aggtcagctt gaaagaatta
    24121 ggggaaatga ttccctcagg tgcaatatca aaatcgggaa ttaatcaccg aattcgcaaa
    24181 ataaatgaat ttgcggaaaa actgcgtgaa gaagcagttt aatccaaaga aaaa
//
LOCUS       DAPBBR010000042        23827 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPBBR010000042 DAPBBR010000000
VERSION     DAPBBR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.042"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(53..787)
                     /locus_tag="RD488_001870"
     CDS             complement(53..787)
                     /locus_tag="RD488_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7657939.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="RD488_001871"
     CDS             1114..1524
                     /locus_tag="RD488_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDT7657940.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="RD488_001872"
     CDS             1517..2218
                     /locus_tag="RD488_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDT7657941.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="RD488_001873"
     CDS             2218..3804
                     /locus_tag="RD488_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657942.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="RD488_001874"
     CDS             3823..4044
                     /locus_tag="RD488_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HDT7657943.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="RD488_001875"
     CDS             4041..4802
                     /locus_tag="RD488_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HDT7657944.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="RD488_001876"
     CDS             5182..5691
                     /locus_tag="RD488_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7657945.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="RD488_001877"
     CDS             complement(5766..6305)
                     /locus_tag="RD488_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDT7657946.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="RD488_001878"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="RD488_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDT7657947.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="RD488_001879"
     CDS             7318..8169
                     /locus_tag="RD488_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDT7657948.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="RD488_001880"
     CDS             8197..8832
                     /locus_tag="RD488_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDT7657949.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="RD488_001881"
     CDS             8852..9625
                     /locus_tag="RD488_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7657950.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="RD488_001882"
     CDS             10033..10830
                     /locus_tag="RD488_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDT7657951.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="RD488_001883"
     CDS             10808..11221
                     /locus_tag="RD488_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7657952.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="RD488_001884"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="RD488_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7657953.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="RD488_001885"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="RD488_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDT7657954.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="RD488_001886"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="RD488_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDT7657955.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="RD488_001887"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="RD488_001887"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDT7657956.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="RD488_001888"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="RD488_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDT7657957.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="RD488_001889"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="RD488_001889"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDT7657958.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="RD488_001890"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="RD488_001890"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDT7657959.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="RD488_001891"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="RD488_001891"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDT7657960.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="RD488_001892"
     CDS             21905..22483
                     /locus_tag="RD488_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7657961.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="RD488_001893"
     CDS             22535..23017
                     /locus_tag="RD488_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDT7657962.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="RD488_001894"
     CDS             23134..23508
                     /locus_tag="RD488_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657963.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4285 c         5115 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtt
//
LOCUS       DAPBBR010000043        23568 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPBBR010000043 DAPBBR010000000
VERSION     DAPBBR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.043"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="RD488_001895"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="RD488_001895"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDT7657964.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="RD488_001896"
     CDS             complement(1172..1867)
                     /locus_tag="RD488_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDT7657965.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="RD488_001897"
     CDS             complement(1880..2596)
                     /locus_tag="RD488_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDT7657966.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="RD488_001898"
     CDS             2926..3531
                     /locus_tag="RD488_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDT7657967.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="RD488_001899"
     CDS             3856..4179
                     /locus_tag="RD488_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDT7657968.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="RD488_001900"
     CDS             4361..5731
                     /locus_tag="RD488_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDT7657969.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7156)
                     /locus_tag="RD488_001901"
     CDS             complement(5861..7156)
                     /locus_tag="RD488_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7657970.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRHVEIPEFEETNFTTLAGFASSRY
                     KEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7386..9344)
                     /locus_tag="RD488_001902"
     CDS             complement(7386..9344)
                     /locus_tag="RD488_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HDT7657971.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9521..9787)
                     /locus_tag="RD488_001903"
     CDS             complement(9521..9787)
                     /locus_tag="RD488_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7657972.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10297..12423)
                     /gene="pnp"
                     /locus_tag="RD488_001904"
     CDS             complement(10297..12423)
                     /gene="pnp"
                     /locus_tag="RD488_001904"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDT7657973.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12611..12880)
                     /gene="rpsO"
                     /locus_tag="RD488_001905"
     CDS             complement(12611..12880)
                     /gene="rpsO"
                     /locus_tag="RD488_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDT7657974.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13131..13694
                     /locus_tag="RD488_001906"
     CDS             13131..13694
                     /locus_tag="RD488_001906"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7657975.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13947..14468)
                     /locus_tag="RD488_001907"
     CDS             complement(13947..14468)
                     /locus_tag="RD488_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDT7657976.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14471..15313)
                     /locus_tag="RD488_001908"
     CDS             complement(14471..15313)
                     /locus_tag="RD488_001908"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HDT7657977.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15306..16031)
                     /locus_tag="RD488_001909"
     CDS             complement(15306..16031)
                     /locus_tag="RD488_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDT7657978.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16207..16503
                     /locus_tag="RD488_001910"
     CDS             16207..16503
                     /locus_tag="RD488_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657979.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17071..18663
                     /locus_tag="RD488_001911"
     CDS             17071..18663
                     /locus_tag="RD488_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7657980.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18676..19416
                     /locus_tag="RD488_001912"
     CDS             18676..19416
                     /locus_tag="RD488_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7657981.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19584..20933
                     /locus_tag="RD488_001913"
     CDS             19584..20933
                     /locus_tag="RD488_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7657982.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21061..21651)
                     /locus_tag="RD488_001914"
     CDS             complement(21061..21651)
                     /locus_tag="RD488_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7657983.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21798..23150
                     /gene="brnQ"
                     /locus_tag="RD488_001915"
     CDS             21798..23150
                     /gene="brnQ"
                     /locus_tag="RD488_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7657984.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6748 a         4746 c         4490 g         7584 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga cgctggaaat
     6061 catctaatgt tagtttgccg gagatgatat aagagccatc tgactgttcc gctatcaatg
     6121 cttcgtccaa atctgtctca tctcggattt ccccgacgat ttcttctaaa atatcttcaa
     6181 tcgtcactaa gccgcttgtc cctccgtatt catcttttaa gatagcaata tgctttccct
     6241 tttttcgcat gatcgtcaat aattttttta tagggatcgt ttcagttgtt acgatcggct
     6301 cttcaatcaa ctgttctact gtcagctggt catctttata agattgcttg atcaaatctg
     6361 gcaaggtgac ataacctaaa acattgtctt ttgattctaa gataaccgga tagcgagtat
     6421 gtccttgttc aatcgaagct tttatcgctt ctttgacggt ttctgaagct tcgaatactt
     6481 gcatggacgt acggtctact tgtatatctt ttgccaaggt atcatcaaat tcaaacacgt
     6541 tttccaaata atgatattct tctttggtca actctccttt ttcataagaa ttcaatgcga
     6601 ctaatgtcag ctcttcttga gacaatgtct cttctccttc agatacgaga cgcacaccta
     6661 atagcttccc tagccctgca gctgaatgat tcaataccca aataaaagga aacattactt
     6721 tataaaaata atgaagtggt ttaactacga acaagacgac cttctccgta ttgacgatac
     6781 tatagctctt aggaagcagt tcgccaataa ccacatcgat atacgtaact aaaataaatc
     6841 ccagcgccac agagattgta ctgctaatag ccgaactaaa aggtagttta ccgatcactg
     6901 gttctagtaa agccgcgaca gatccttcac cgacccaccc gatgatcaaa ccggttagcg
     6961 taattcctaa ttgactagct gataaatagt tatctaaatg gtgtgtaaca tgaagagcta
     7021 gcttggcgtt ctttacattt tccttttcta gttgttccaa tcttgatcgt ctgattttca
     7081 ctaaagcaaa ttcacttgct acaaaaaatg aagtaattgc aatcatcaaa aataaaataa
     7141 tgaaattgat aaccatattc tcccgccttt ctctttttct attgtaccct ttttctacaa
     7201 aaagattgaa aataatgcgt attcatattt aggaataaaa aaggagatgc ggcatttttc
     7261 agccacatct ccttatcact tcaaaatcat tgcgttactt gttgctaaac agctttttca
     7321 tgacctctga taaacggtgt tcaagtagct gacattcgac attagttcag gtcaaagcgc
     7381 tactttcaca accgctcttt caaccatgtt ttccgagtat ttccaatgat aagcggaaca
     7441 gtttcatgtt ttacttcgct gtactctagc ccaaaccatg tttctggcga ggtagcgatt
     7501 tttttgattg ccagttttgc ctgcatgatt tgacgttgcc attttcctag agttgtcaca
     7561 ttggaaacta cttcatcaat caggacaaat tggaaatcgc caacttctcg ccctggtgtc
     7621 agagagtatc tttgtggctg ttttggcaaa cggccttgtt tcatcaaatc atggatgact
     7681 tggcgaacat atacgttgat ttcctgttgg accctgaaac ctaagaacag attcacttgg
     7741 acaataaaat cagtgtccat catatctact tgatattctt tcgtatatgg ctcatccgtc
     7801 acttccacat gaacaaacca atagactcgt gctcttttag gccgtttatc taaaatcgaa
     7861 tagatgaact gtcggccaac tttatcttca gccatatcag gaaccaagaa gaccacattt
     7921 gtctgataga ttggtaaaga agtatcatca cgtaattctc taagctgcgg gatataatct
     7981 ctcaaagaca catcctcggt tgacgattcg cgaataatgt tcccttgttc ccaaataaac
     8041 atcacgacta agatgatcaa accaatcaga acggctacaa aaccgcctcg gaagaatttg
     8101 acaacacttg agataaagaa aacgacttct atcgcaccga agaaaaaggt aactaaatat
     8161 gcaagccaac gagaatgccc attttggata agataaaagt aaagcagtgc tgttgtcatc
     8221 aacatcgtca cagtgatcga tagaccgtaa gcagcttcca tatgatgaga cgttcggaat
     8281 gtgacaacca ctagagaaca ggcgatccat aaaatcagat tgactgctgg gatatacatt
     8341 tgcccgatac tgttcccagg atacatgatc tttaaccgag gcagcagttt caacttgatt
     8401 gcttctgaaa ctagcgtaaa cgaacctgta atcaatgctt gcgaagcaat gactgcagcg
     8461 actgttgcaa aagcaacgcc gatcacgatc caactttgag gcatcatttg gaagaatgga
     8521 ttcaggttct tgatttgctg tgcttcaggg ttttgataaa cattcaacaa ccacgcagcc
     8581 tgcccaaaat aattgataac caaacaaatt ttgacgtaag gccagctcag acgaatattt
     8641 cgtttgccga catgtccaag atcggaataa agcgcctctg cacctgtcgt agccaggaaa
     8701 atatttccaa gaatgaacaa gcctaatttg ttatctgcac taaaaagcag ctggatagca
     8761 taataaggat tcagtgcacg gataactgtc cagtcttgac tgaagttcat taatcccatt
     8821 acgcctaaaa aagtaaacca agcgaacatg attggtccga atgcttttcc gacaatatct
     8881 gtaccaaagc gttggaccat gaataaaaca aaaataataa ctaaagtgat aatgacgatc
     8941 acgttctggt tattaccgaa ccggtcaaaa aactgcggaa ttcctcgcaa gccttcaatc
     9001 gcagtcgtta ccgtcacagc aggggtcaat accccatctg ctagtaaggc agctcctccg
     9061 atcattgcag gaatgatcaa atatttccca ccttttcgga caagtgtgta gagtgagaaa
     9121 attccacctt caccatggtt atctgcattc aatgcaatca cgacatattt gattgttgtc
     9181 agtagagtca atgtccaaaa aatcaatgag actgatccga taacaaaatc aggattgatt
     9241 cctgacaatc cgccattatc ttcaacaatc gatttcataa cgtaaagcgg acttgtcccg
     9301 atgtctccgt agacgactcc catcgctaca agcaggccag ccattgatat ctttttggta
     9361 ttgtgcgttg ttgccacgtt tttccctcat ttcttgttat atggatatcc tttaggtaag
     9421 cttgaatgat agatgatatt cttatccatg acacccgctt tcctaaattg cttctaatta
     9481 tccaagtaac acactgaagt gtcaacttat ttgaataaaa ttattctttc tttggacgtt
     9541 ctctgatacg tcttgccaca aatgaataaa gagcaaggca aaaaattgca cccaataatg
     9601 ctggtatcaa ataaaaaccg ccgagttccg gtcccagtgg tcctagtaaa aattcgccga
     9661 gccaactacc taaaaaaccg ataatgatat ttccagatac gcctcccggg acttcctttc
     9721 ctaaaattgc gccagctatc aaacctaata taccgccgat aaataacgac cataaaaaat
     9781 tcagcatctc ctttccctcc tttatccata tttctcactt ttattttacg ctttattcag
     9841 aaggactcca aaaatatgcg ccaagaaact ccagaaaaaa agaagttgta acaaaagtgt
     9901 tcagcttatt tccgtagaag ctgcttctgg aacaccgtga atcagaggtt gtgaaatcag
     9961 cggtttgacc tgagtattag agaaacaaac ggaaaaatag ttcctcatat tttgccgttt
    10021 tttgagctaa tatcgaggga cagctgattg aacatcgttt attggagagg ttgtaaaaaa
    10081 gctgttctgc atcaagtaat aagaacagcc aagtaaaaac agctcctaat gtttttaact
    10141 tggctggact tattaccgca gatgcaagct tttgaacacc gtttattcga aaaaaaagga
    10201 ctgtgacacg gcttttgtca cagtcccctt ttttcgaata attattgtcc ccctgtcacc
    10261 ttcacgatca caagtacatt attcctatga attaaattat ttttcttcat ttttcgttga
    10321 accatcttcg ttcaacattg cttttcttga cagatttacg cgtccttgtt tatcgatttc
    10381 agttactttc acaaggatct catcacctag tttaacaaca tcttcgactt tattgacacg
    10441 atcgtttgct aattgggaaa tatggacaag tccatctttt cctttgatca agttgacgaa
    10501 tgcaccgaat ttttcgatac ggacaacttt ccctagataa acttcaccaa ctttgacttc
    10561 tttggtcaaa tcttcgatga tcttgatagc ttttttgatc atttctgcat cagctgaagc
    10621 aatacttact tttccatctt gatcgatatc gattttcaca ccagtttcat cgatgattcc
    10681 gttgatcgta tcgccgcctt taccgataac atctttgatt ttagcaggtt cgatctggat
    10741 catttcgatt tttggtgcat attggcttaa ttcttcacgt ggagcagcaa tcgttgaagt
    10801 caattcttct aagatttcca tacgtgcttg ttttgcttga gttaatgctt cagttaggat
    10861 ttgttctgtg attccttgaa tcttgatatc catctgtaaa gcagtgatac catcttttgt
    10921 accggcaact ttaaagtcca tatcgccaag atgatcttcc agcccttgga tatcagttag
    10981 gatcgtatag ttttcaccat cagaaacaag tcccatcgca ataccggcga ctggcgcttt
    11041 gattggtaca cctgcatcca tcaatgctaa tgtgccagca cagatacttg cttgggaaga
    11101 agaaccattt gattccaata cttctgctac taaacggatc gtataaggaa attcttcttc
    11161 tgaagggatt acttgtgcta acgcacgttc acctaatgcg ccatgtccga tttcccgacg
    11221 ccctggagag cctgcacgtc ctgtagaacc aacagaaaat tgagggaaat tgtagtggtg
    11281 gatgaatcgt ttgctgactt ccacccctaa accatcaatg atttggtgct ctcctagagg
    11341 tgcgagtgta caagctgata aagcttgtgt ttgtcctcgt gtgaacaaac ctgatccatg
    11401 tacacgtggc aataagctga cctctgatga caatggacgg atttcatcca atttacgccc
    11461 gtcaggacgg atcttatcga tggtgatcaa ttcacgtacg acatcttttt caagatcttc
    11521 tgtgatttgt ttaacttctt tcaacaagtg atcttcatct tcatgacctg caaatttctc
    11581 agcataagct tcgcggatat cgatcttcac ctgctcgata ttatcttcgc gagcaagttt
    11641 ttcttcagtc attactgctg ctttcattgt agcgtaagaa gcatcaaaga tttctttttt
    11701 caatacttca tcaacttgca gtaaagtcac ttccattttt tctttcccta ctgcttgaac
    11761 gatttcttct tggaaagcaa ctaactcttt gatagcgtca aaaccaaaca gcaatgcacc
    11821 aagcatgtct tcttctgaaa cttctttcgc gccgctttca accatattga tggcttgttt
    11881 cgttccggca acagtcaatt cgatatctgt ttgttctgct tgttctactg ttggattcaa
    11941 gacgtactcg ccatttacac gaccaacttc tacgcctgcg attgggccgt caaatgggat
    12001 atctgagatt gatagtgcta aagaagaacc tagcattgct gccatagctg gcgagcagtc
    12061 tgtttctaca ctcatcacga tgttcgttac ttggacttca ttacggaagc cttctgcaaa
    12121 catcgggcga attggacggt cgatcaaacg ggcagtcaat gttgcttccg tacttggacg
    12181 gccttctcgt ttgatgaaac ctccagggat tttccctgct gcatacattt tttcttcata
    12241 attgatcgtt aatgggaaaa agtctgtatc ttttgcttct ttagaggcca cagctgcact
    12301 taagactact gtatctccat aacggactaa aacggctccg tttgcttgtt ttgctagctg
    12361 accgacttcg atttgtaagg gacggccgcc ccatgtcgtt ttgaatactt gtttttctga
    12421 cataacttct ccttttcctt ctcgtgaaag caagacgcta ctaaacaaat gaaaactgcc
    12481 gaaagccgtc ttttgagcag ctttcatttg gttagtagga gtccatctag cttgatcacg
    12541 gaattttact taattgatat acgagtaaaa aaagtgagat tcatgtgaat cccactcttt
    12601 ttgactaaaa ttaacgacgc aagcctaaac gtttgatcaa ttcgcggtaa cgttgaacgt
    12661 cagttttacg taagtaagct aacaagttac ggcggtgacc aacttttttc attaggccgc
    12721 ggtatgaatg atggtctttt ttgtgcacgc gtgcatgttc attcaagtgg ttgatttctt
    12781 cagttaatac agcgatttgt acttctggag aaccagtatc cccttcatgg cgagcgtatt
    12841 cgttgatgat ttcattcttg cgttcttttg aaattgccat ttctttcacc tctttcgatt
    12901 attcccctgc gactgagtaa aacgttggtg attcgcttaa ccaagtggca ggtcatgtgc
    12961 ctagagcaca cagctatact ttacctgaaa ccgggttgaa aatcaagtag ttaatcatta
    13021 agaaaaggta gttttcaaac aatcttacta ctacttttcc atttttgtgg taaactataa
    13081 tgcgaaaata gacttgaaac acagtctttt aagaaagggg tacatattcc atgattacaa
    13141 tggatgatat cattcgtgaa ggaaatccga ccttacgcga agttgcaaaa gaagtttctc
    13201 ttccattaag cgaagaagat atctctttag gaaaagagat gcttgagttc ttaaaaaaca
    13261 gccaagatcc aatcaaagct gaagaactac acttacgagg cggtgttggc ttagctgctc
    13321 ctcaattaga tatttctaaa agaatcattg ctgttcacgt accaagtcct gacccagagg
    13381 cagatggacc ttctctaagt actgttatgt ataatcctaa aattttgagc cattctgttc
    13441 aagatgcttg tttaggggaa ggtgaaggct gtttatctgt tgatcgagaa gtaccaggat
    13501 atgttgttcg ccatgccaaa atcactgtgt cttattatga tatgaatggt gaaaaacaca
    13561 agattcgttt gaagaattat gaatcgatcg tcgttcaaca tgaaatcgac catatcaacg
    13621 gtgtgatgtt ctatgaccac atcaacgatc aaaatccatt tgcactaaaa gaaggcgtat
    13681 tggtgatcga gtagagaatt ggcaggttcc ttcgatacta tgctacaaga aagctttata
    13741 aaaaagggga gtgctcaaaa gctgcacttc ccttttttat gtttctccac taatcgaaat
    13801 ttagatagac atctagaaat cgcaattcca aaaaattctg tgtattggat acgcatcttt
    13861 tcttattttt tcttatttct tccatatggg tgtttatctc agagatgata gaatagtttc
    13921 taggataaaa agtagcagct acgatgttat ccttcgtaga ggattcctgc ttcagctagt
    13981 ttttgtttga tgtttttcag catatgcttt tctgggtagc ggatcgtatg cagatggatg
    14041 ccgcctgtta attcggataa caaagtagca ttactttttt gataacgtct cataaaggaa
    14101 tcgatatctt gtggcgtttt gatgtgcaaa gttcctgcta actcaccgta aaggggatgt
    14161 tccacaatta catcaatgat ttcaccacca ttttcaacga ttagtctcag ttcttcttct
    14221 gtttgatctt ttccatgctg gacagcgatt ttactgatgt gcccagtatt ggtttcttct
    14281 gtttcgagga tataacctct tgctgttgcc acgatacttt tacctgcagc tcgtagtaaa
    14341 gcaatatcgc ctacaatgat ctgacggctg actccaaaag ttttcgcaaa cttgctagca
    14401 ctcactggtt tttctgtatt tgccaaggtt tgcatgattt gttttcgccg tgtctctcct
    14461 tcgatcacac ttattcctcc ttcattttgt tttggtattc gcgcgagtgt ttcatcaaat
    14521 caacatacgt gtctgttatt gtttccttat atcccttatt tttcagcaga ctaacaactt
    14581 tatccaatac ttgctgctct ctttttgcat cataaactgc ttggttttct tcttttttca
    14641 cttgtcctat tttagttacc gtatccattc ttttttctaa taaagcaacc aactctcgat
    14701 cgatcatatc gatcttatga cgtaatgttt caagagactc ttctgttagt tcttcctcta
    14761 ctgtcttgat gatacgagca ggatttcctg caatcactac attgtcggga aaagatttgg
    14821 tcacaaccga acctgcgccg actactacgt tgtcccctag agtgacaccc ggcgtgacga
    14881 taactcctcc gcctaaccaa acattattac cgattttaat gggttttgcg tactccagac
    14941 cgctgttacg tttcactgga tgtagtggat gcgtcgccgt gtaaagctgg acattcggag
    15001 cgaacatgca gttatcaccg atttcaatcg tgctgacatc taaaaatgta caattgaaat
    15061 ttgcataaaa attctcccca acaaatatat tatatccgta atcaaaattg ataactggct
    15121 ccatatagat ttttttccct gtacggccaa aagtctcttt caacaattgg gatcgcagtt
    15181 ccgctgattc tgcttggttg atgatttggc tttgacttct tgcaaacata cggtcggcaa
    15241 ccagctcagg atcattggca aaataaagct cgcctgcaat cattttttct ttttcggttt
    15301 tgaattcagt cataatctgc tcctaattct tgtatttttt tgaaaacaac cgctccgtct
    15361 tcttgaataa acgtataagg ctccgctaaa taaacaggcg tttgattgat tactaagatt
    15421 ttggctgacg gctggcgaaa ctgtaccaga tcacaaaacg gatgaacttg aaaactcgtt
    15481 ccaacaatga cgatcagctc tgcttggctg acggcataag ccgcctgctc catgactcca
    15541 tcttgaaacc cttcaccata taacacgatg tctgggcgta tttgtcctcc gcatgcttga
    15601 tgtttgtcgc tgtgaagata ttctttccag tctaccgttt gttgacattt tcgacaatga
    15661 cattgataca gactcccatg aaaattgacg agttgcgggc ttttagcctt tgcgtgcaaa
    15721 ccgtcgatgt tttgggaaac aacccaaaca tttttttctt tcgctagatg tgctatttcc
    15781 aaatgaatga tattgggttt tgcttcagga tgataaatct ttttgacaaa ttgatagaat
    15841 ttatccggtt cattcaccat tgcttgatga ctcagcaagt attccggctg ctccatcccg
    15901 tggtagattc ctgacaaaga tcgatagtct ggcactccag aaggtgtgga tacccctgca
    15961 ccggtcaaaa atgtaatttg ctgataagct aatatctctt ttgctgcttc gtctactgtt
    16021 aattgtttca tgttttgtca cctcactttc cattatagcc catactcgaa caaatttatt
    16081 gttgaaaagt cagaaaaatg ggaataaaaa agtgttatgg gcatttgagc aatttatcac
    16141 aatgttcact gacaaaagaa tgaaaacgtg ttacaatact gctgtataaa agtgaggtga
    16201 atcgatatgt taccattctt tatttattgg ggcgttattc tggcttgtat cgcctggtta
    16261 gcgttaagcg tttatttctc tgttttttat cttgtacgca aagaaaatgg aaatctttgg
    16321 gcttttgctt tattcaacgt gattgccgca attgttttag ccattacatt agccgtatat
    16381 cgaacatggg gctggggaat cacccaatac tcaagtttga tttatctaat attagccatt
    16441 tatggcgtcg ttgttctttt gcaagcgatc ctaggacgtg agccaaagaa agcggcagct
    16501 taaatgatcg agatggaact ggacacagga aattttctgt tctagttctt tttttattgt
    16561 attacataca tttttgtgta taattatact atcgtttgca atggatagat gattcacatt
    16621 ttgattgttt tttcggtaaa agtaaagatt tctatattta tcagtatttt ttcaaaaacc
    16681 agcagttata gattgacaaa gcctctcgag tatcgtaaac tttttttgta taaataactg
    16741 aatacgagat gcctcaatca atgaggtaga ggtcgcgaga atcattaacc ctgtggagtg
    16801 aagcaaacat ggagaagcag gaatagggag gatcgccgaa atgtgcactt ttttgcttgg
    16861 agtgtatgtt gggacgcaag ttaagagctt gcggactgtc ttagcagtga tgctaagttg
    16921 cgctatgttt tgtgagaggt ttatcacctt atggaatttt agcggccttt ttatatctat
    16981 aaatcggtcg ctttttattt tttcagataa agctttaccg catttcatct agaccgctcg
    17041 tgtatcatat aatcagaaag ggagaaaaaa atgaaaaaaa atatggtttc agttgccgta
    17101 ctatttgctt ttgtcttctc actattcagt gtgggatctc tggcaaatgc agatgaaaaa
    17161 acaccgagcg atgagtttcg cgtaggtatg gaggctgggt atgcaccctt caactggtct
    17221 caacaaacag atgagaataa tgccttgcca attcaaggcc aaaatagtta cgccggcggt
    17281 tatgatgttc aaatcgctaa aaaagtagca gatggtttag ggaaaaaatt agtcatcgtc
    17341 caaacgaaat gggatggtct ggctcctgcc cttcaatcag gcaagatcga cgcgatcatc
    17401 gccggaatga gccctactgc tgaacgacga aaagaaattg attttaccga tccttattac
    17461 gaatcacaat tagtagtagt agttcaaaaa gatagcaaat atgcaaaagc aaaaagttta
    17521 gcagatcttt ctggagcaaa gatcactgct cagttaaata cattccacta tactgtgatc
    17581 gatcagatac cagatgtgca gaaacaacaa gcaatggata atttctcagc aatgagaaca
    17641 gctttagctt ctggaatgat cgatggttat gtcagcgaac gtccggaagg tgtaacggca
    17701 actagtgtga acaaagactt ggaaatgctt gaattcagcg gtgcagatgg cttccagaca
    17761 aacccggaag atgttcagat ttctgttggt atgcgtaaag gcgacccgga tatccaaaaa
    17821 gtaaaccaga ttctttctgg catctctaac gatgaacgaa ccaaaattat ggaccaagca
    17881 gtcaaagatc agcctgctgc aactgatagt gaagaaaaac ctggcatcat ttctgatttc
    17941 actacgattt ggaaacaata cggcaatatg ttcttacgag gtgctggact taccttgttc
    18001 atcgcattga tcgggacagt tgtcggtact acacttggat tactgattgg tgtcttccgt
    18061 tcggtacctg aatcaggaaa tgcactgact cgcttcttcc aaaaaatcgg aaatgcactt
    18121 ctttctatct atgtcgaagt attccgcgga acaccgatga tggtacaagc aatggtcatc
    18181 ttctacggtc tggcactcgc ttttggcatt tcattgaacc gaacgattgc cgctttgttt
    18241 attgtctctc tcaatactgg agcttacatg acagagatcg ttcgtggggg gatttttgca
    18301 gtagatgaag ggcagttcga agctgcgcaa gccattggta tgacccatgg ccaaacgatg
    18361 agaaaagttg ttattccaca agttttacgg aatatcttgc cagcaacagg aaatgagttt
    18421 gttatcaata tcaaagatac agcagtttta agtgtaatcg gcgtagctga tttgttcttc
    18481 caaggaaact ctgcttccgg tgcgaatttc caattcttcc aaacatttac gatcgtcggg
    18541 atcatctact tagtcatgac ctttacgatc accagaatcc tgcgggcggt agaaaagaaa
    18601 atcgatggtc cttcagctta taccaagctt gaagaaatcg acaattcaaa tttgcaggaa
    18661 taaggaggaa gaatcatgaa tgaaaaaatt attgaaatca aacatctaag aaaaagcttc
    18721 ggtgaaaatg aagtattgaa agatatcagc gtaacagtca ataaaggtga agttgtgacg
    18781 atcatcggtt cttccggttc tggtaaatct actttcttgc gctgtatcaa tttactggaa
    18841 aaaccaacag gcggcgagat catttataat ggagaaaatg tattagctcc taaatataat
    18901 ttacctaaat atcgaacgaa tctaggtatg gttttccaat ccttcaacct gttcaacaat
    18961 atgaatgtct tggaaaactg tatgtctggt caaacaactg tcctgaaacg agataaagaa
    19021 actgccaaaa aagtagcaat cgaaaatctg gaaaaagttg gtatggatcg ttatatcgaa
    19081 gccaaaccag cacaattatc tggtggacag aaacagcgtg tcgcaattgc tcgggcatta
    19141 tcaatgaatc cagatgtatt gctattcgac gaacctactt cggcgttaga ccctgaaatg
    19201 gttggcgaag tgcttaatac gatcaaagac ttagcacata ctggcttgac aatgcttatc
    19261 gtgacgcatg agatggaatt tgcaaaagat gtatctgacc gtgtcatttt tatggataaa
    19321 ggtgtgattg cagaagaagg tacaccagaa gatatctttg tccatccgaa agaagaacgt
    19381 acaaaagaat tcctttcacg tattttaaat gcttaggatc aatagctgat tgggacaaag
    19441 agctgcggtg tttaccgcag ttctttttta tgaattactc ataaaaggta aatttctgaa
    19501 aattttggaa tcttagttgt gtttttcaga aaactctctt aatatggaag taattaaact
    19561 tttttagtta ggatgattta aaaatgaatg aagagcaaga actgcagcgt ggactgaaaa
    19621 atagacatgt ccaactgatt tctattggcg gagcgattgg aacggggttg tttttaggtt
    19681 ccggaaagtc tatccagcta gctggccctt cgatattgct cgcctatctt attactggat
    19741 gcatctgttt tttcattatg cgtgcgttag gcgaacttct gttatcaaac accaataacc
    19801 attcttttct ggattttgtt gcagaatatc ttggcaaaaa agcggctttc atcactggct
    19861 ggacgtattg gttctgctgg gtatcgattg caatggccga tttaacagcc atcggaatgt
    19921 atgtacgcta ctgggcgcct ggtgttcctc agtggcttcc tgaactgatt gcattaggtc
    19981 ttcttctttg cttgaatatg gtggctgtct cattgtttgg tgagttagag ttttggtttg
    20041 cattgatcaa agttgtagcg atcattgcct ttatcctcgt aggagcttat atgatcctca
    20101 cccactatac gacagatatt ggcacagcca gtatcacgaa tctatggtct catggcggat
    20161 tctttccaac tggtgcaaaa ggatttatct tagctttcca aatggtaacc tttgcttttg
    20221 ctgggataga attagttgga ttagtcgctg gagaaacaga aaatcctgaa aaagtgttgc
    20281 cggaagctat caataatatt cctatcagga tcatcttatt ttacttagga tctctttttg
    20341 tcattatggc aatctatcca tggaacagct tgaatccaga taacagtcca tttgtagaag
    20401 tattttcgga aattgggatc acgattgctg cttccttgat caatttagtc gtattaagtg
    20461 cagcagcttc tgcctgcaac agtgcaatat atagtacagg acgtatgctt cgttctttag
    20521 cgcaagaagg cagtgcccct aaaaaattca aaaagttaac aacacatcat gtgccaggga
    20581 atgctttgac attttctact atcgtcattt tcatttctgt tatcttgaat tacgtgatgc
    20641 ctagtgaagt attcacacta gtaagcagta ttgccactac ttgtttcttg tttatctgga
    20701 gtatgcttgt ctacacgcac atgaaatatc gtaaaagtat cctcggcaaa aaagctcatt
    20761 catttaaaat gccgttgtac ccatttagta attatctggt atttctttac atggcctttg
    20821 tgtgtgtcgt cttgttccta ggaaaagata cgagaatcgc tttattacta acacctgtgt
    20881 ggttcttgct tctattacta atctatcata tgaaatatga acgtaagaag taagaaagta
    20941 gttgtgacag aagtggtcag cttcgagaaa taagaaggaa tttacgaaaa ttgcttctta
    21001 aatttttgtg aaatttcggc ttatttcttg gagataaaag cttctgtccc agcctctttt
    21061 ctatttcccc ggaaacaacc gctgataata ggcatctgct tttttatagg aaaaaatcca
    21121 aataccagat acaaaaaaac gtccgaataa cccgatcaac ggtacaaaaa agacaccggc
    21181 aatcaagcat aagttaatca tcatggagat aagacttcga cggtcctttg acaaaactct
    21241 cacgacatgg gaatctggtt tatttgcttt catgatttgc ctcatcaaga taccaaaaga
    21301 aaaactccac atcgtgtata ctaagacata agccatctca ggccaaaaag cttcagggtt
    21361 acgcccgacc caactagtaa cagaaggaca taaagtcagc caaaagagca aaaagatatt
    21421 cgaccagacc actcggtaat taattcgttc tgccatctga aatatacgat gatggttcac
    21481 ccagatcacc gcaacaaata taaagctgat ggtataagct aataatgtat ttcggatgac
    21541 ccataaagaa tgaaagctag atgtattagg gatcttgatc tctaatacaa taactctcaa
    21601 aacaatggct accactccat cagtaaatgc ttctaatctc gactttgtca cgatgattcc
    21661 tcctcagatg attcagcgct tttattttat cacttacgtt attaaataac catcgtttta
    21721 tatagggaat tttctgaaaa ttgttgcata tttttcgaaa ttttgttact tttaaaaaaa
    21781 ccgtaaagga gttatgtatg acaaaaaaat tatcatttaa agactatctt tttataggct
    21841 ccatgctttt cggtctattt tttggtgctg gaaatcttat ctttcccgtt catttgggtc
    21901 aagaagcagg cgctgctacc ttttgggcga atctaggttt cttggttacc ggtatcggtc
    21961 ttcccttctt aggggtgatt gccattggtg tatcgaaaag ctcaggtgta tatgaattag
    22021 caaaacggat aaatcaaaca tatgcgatgg tttttaccat cttgctttac ttagttatcg
    22081 gaccgttttt tgctttacct cgccttgcaa ccacatcttt cgagattggt ttagcaccat
    22141 ttatcgatcc tagcagacag acgctatatc tagcaatttt cagtattgta ttttttgtgc
    22201 tggcttggtg gttttcaaga aaaccgacaa agatattaga ttatgttgga aagttcctga
    22261 atcctgcatt tttggtttta ttaggtgctt tgcttctcct tgcttttttg aatccactag
    22321 gttctgtaaa tcaagcgcct attcagccaa attatcaaga gcatgctttt ttcacagggt
    22381 ttactcaagg atataacaca ttagatgcgc ttgctgcttt agcatttggg atcatcattg
    22441 tcacaacaat ccaaaacatg ggtgtaacaa aacctgctga aatcgctaaa gacacgatca
    22501 aatctggtgc gatcagcatt atattgatgg gaatcattta tactttgctc gcttatttag
    22561 gtgctatgag cttaggtagc tttgctctaa gtgaaaatgg cgggatcacg ctggctcaga
    22621 ttgctgatca ttatttaggt acttatggca gtatcttatt agcatttatc gttatattag
    22681 cttgcttgaa gaccggtatt ggtttgatta cagcttttgc agaaacattc acagatttgt
    22741 ttccgcaaag aaattacgca ttctttgttg cacttgctag tatccttcct tgtttagcgg
    22801 caaacgtagg cttgacgaat atcattcaat tttcgttgcc tgttttgatg ttcatctatc
    22861 cattagcaat gacactgatt ttactagtgt tagttggtcc tttgtttaag cagcgtacgg
    22921 ctgtttatcg aatgactact tattttacat tgattgcttc gatttttgat gggttgaacg
    22981 cttgcccaga aactatcaaa caaacaccta ttgttcaaaa tcttttatat gttgcggaaa
    23041 gctacttgcc gtttttcaaa ttggggatgg ggtggatcgt accagcagtt atcggttttg
    23101 ttatcggact gatttggagt ttcgctaaga aagaagaagt agcagattga taaaagaggt
    23161 tgtgaaagag acgttcagcc ttgagcaata aaaagtaatt ttgaaaaatg gcttctcaca
    23221 tttttgcata aatttgactt aataccgaga aactgacttt tgaacaccgt ttattgagag
    23281 gtcgtgaaaa agccgcttag tttcaagtat taagaaatat tttgtgaaaa tggcttctca
    23341 catttttgca taaatttgac ttaataccga gaaactggct tttgaacacc gtttattgag
    23401 cgtctataaa ctgacctgag tattagagaa acaaaacggc aaagtagctc catatacttt
    23461 gccgttttgt tttgaactaa taccgaagag aagctgatca aacaacattt cttttataat
    23521 atagatttta gacatatata tgatataaaa atagttttcg caaaaaaa
//
LOCUS       DAPBBR010000044        21595 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPBBR010000044 DAPBBR010000000
VERSION     DAPBBR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.044"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            144..542
                     /locus_tag="RD488_001916"
     CDS             144..542
                     /locus_tag="RD488_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7657985.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="RD488_001917"
     CDS             526..1221
                     /locus_tag="RD488_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDT7657986.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="RD488_001918"
     CDS             complement(1815..2702)
                     /locus_tag="RD488_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7657987.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="RD488_001919"
     CDS             2887..3726
                     /locus_tag="RD488_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7657988.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="RD488_001920"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="RD488_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HDT7657989.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="RD488_001921"
     CDS             5194..5550
                     /locus_tag="RD488_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7657990.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5553..6710
                     /locus_tag="RD488_001922"
     CDS             5553..6710
                     /locus_tag="RD488_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7657991.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="RD488_001923"
     CDS             complement(6736..7176)
                     /locus_tag="RD488_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7657992.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="RD488_001924"
     CDS             7336..7842
                     /locus_tag="RD488_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7657993.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9923
                     /locus_tag="RD488_001925"
     CDS             8010..9923
                     /locus_tag="RD488_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDT7657994.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9928..10929
                     /locus_tag="RD488_001926"
     CDS             9928..10929
                     /locus_tag="RD488_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7657995.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11131..11337)
                     /locus_tag="RD488_001927"
     CDS             complement(11131..11337)
                     /locus_tag="RD488_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDT7657996.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11983..12831)
                     /locus_tag="RD488_001928"
     CDS             complement(11983..12831)
                     /locus_tag="RD488_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7657997.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12830..13897
                     /gene="gnd"
                     /locus_tag="RD488_001929"
     CDS             12830..13897
                     /gene="gnd"
                     /locus_tag="RD488_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HDT7657998.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13899..14900
                     /locus_tag="RD488_001930"
     CDS             13899..14900
                     /locus_tag="RD488_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDT7657999.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14897..15181
                     /locus_tag="RD488_001931"
     CDS             14897..15181
                     /locus_tag="RD488_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDT7658000.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15214..16011
                     /locus_tag="RD488_001932"
     CDS             15214..16011
                     /locus_tag="RD488_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7658001.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16025..16858
                     /locus_tag="RD488_001933"
     CDS             16025..16858
                     /locus_tag="RD488_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658002.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16876..17733
                     /locus_tag="RD488_001934"
     CDS             16876..17733
                     /locus_tag="RD488_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7658003.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17755..18264
                     /locus_tag="RD488_001935"
     CDS             17755..18264
                     /locus_tag="RD488_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7658004.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18301..18702
                     /locus_tag="RD488_001936"
     CDS             18301..18702
                     /locus_tag="RD488_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658005.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18814..19167
                     /locus_tag="RD488_001937"
     CDS             18814..19167
                     /locus_tag="RD488_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658006.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19201..19644
                     /locus_tag="RD488_001938"
     CDS             19201..19644
                     /locus_tag="RD488_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7658007.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19661..20746
                     /gene="uxuA"
                     /locus_tag="RD488_001939"
     CDS             19661..20746
                     /gene="uxuA"
                     /locus_tag="RD488_001939"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7658008.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20739..21452
                     /locus_tag="RD488_001940"
     CDS             20739..21452
                     /locus_tag="RD488_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7658009.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7444 a         3313 c         4494 g         6344 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga
     9841 aacattcgct tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga
     9901 tttggcgaag aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta
     9961 ccagttatca tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag
    10021 ccgattagct tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc
    10081 cgaccagatg atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat
    10141 ccttcaaagt acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa
    10201 ttaccgattc ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt
    10261 cgtgattatt tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat
    10321 gaacgatcac cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa
    10381 gcagctaaaa aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat
    10441 tcggcaggtg cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa
    10501 aaagctgatc atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg
    10561 tctggtctgt tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt
    10621 tatgaaaaat gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc
    10681 aaaagtttag ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat
    10741 ggaaatacaa atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg
    10801 ggggtgaaag tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat
    10861 cagtttgatt tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc
    10921 aaggagtaaa gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca
    10981 aggagcaatt tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag
    11041 gagttagaga tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg
    11101 tcacgatctc ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa
    11161 agcaacaaat ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa
    11221 gaatgctggt tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat
    11281 agcaaataaa atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag
    11341 cagcacctcc ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag
    11401 tttgttagga tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat
    11461 aagcaattaa tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca
    11521 ataatagaaa atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc
    11581 caaaaattcg atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa
    11641 taaaattaca aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt
    11701 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag
    11761 aaaagataaa ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg
    11821 aataatacca atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta
    11881 ttgatgttct gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg
    11941 ctttttttgt tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga
    12001 aatagtatgt cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa
    12061 aatcacatat agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga
    12121 tcggaattct gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga
    12181 agaattagct tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc
    12241 aatatggatt gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc
    12301 cgtcaataaa gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat
    12361 aggggaacgc aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc
    12421 gaaaaaatag acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg
    12481 ttgtaacaac ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc
    12541 catagtgagc tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc
    12601 attttcttgg atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt
    12661 tgtaaattga aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg
    12721 actatgactt actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg
    12781 gctgaagtcg ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc
    12841 tcattttcat aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag
    12901 agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt
    12961 gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg
    13021 aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact
    13081 cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga
    13141 gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc
    13201 tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat
    13261 tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca
    13321 gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca
    13381 tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt
    13441 caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt
    13501 cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt
    13561 ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa
    13621 tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca
    13681 tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt
    13741 tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag
    13801 gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg
    13861 gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa
    13921 tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag
    13981 ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt
    14041 tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt
    14101 ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg
    14161 atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac
    14221 gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac
    14281 aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga
    14341 cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg
    14401 aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt
    14461 tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag
    14521 atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag
    14581 aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg
    14641 atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg
    14701 ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga
    14761 ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg
    14821 tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga
    14881 gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc
    14941 tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata
    15001 cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa
    15061 attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg
    15121 tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta
    15181 gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga
    15241 atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct
    15301 gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct
    15361 gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc
    15421 gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt
    15481 ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag
    15541 attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag
    15601 ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat
    15661 aaatacgcaa gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg
    15721 gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca
    15781 ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg
    15841 ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg
    15901 gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa
    15961 tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg
    16021 acacatggaa acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt
    16081 tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac
    16141 tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc
    16201 tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc
    16261 tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc
    16321 gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt
    16381 catcaatact tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc
    16441 tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct
    16501 tgttttcatt gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga
    16561 gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat
    16621 cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta
    16681 ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg
    16741 gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac
    16801 aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt
    16861 taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc
    16921 acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac
    16981 tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa
    17041 ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac
    17101 actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa
    17161 agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac
    17221 acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc
    17281 gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc
    17341 gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca
    17401 agacaagctt tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag
    17461 acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac
    17521 tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag
    17581 gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtagtaat gggtgtgtac
    17641 ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata
    17701 ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt
    17761 gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta
    17821 tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa
    17881 tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt
    17941 acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt
    18001 ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa
    18061 gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa
    18121 tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc
    18181 gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta
    18241 ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa
    18301 atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag
    18361 cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt
    18421 atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt
    18481 tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt
    18541 catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac
    18601 tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat
    18661 aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta
    18721 gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa
    18781 acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat
    18841 gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac
    18901 agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca
    18961 gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa
    19021 gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg
    19081 cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc
    19141 aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta
    19201 atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg
    19261 gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac
    19321 atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc
    19381 atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc
    19441 aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca
    19501 atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa
    19561 caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa
    19621 aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg
    19681 gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa
    19741 tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat
    19801 tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt
    19861 agcgatccac gatgcaatca aggcagggac agatgaacga gattactata ttgataacta
    19921 tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa
    19981 accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc
    20041 tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat
    20101 acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt
    20161 cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac
    20221 ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca
    20281 tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga
    20341 cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg
    20401 atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg
    20461 catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac
    20521 ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca
    20581 agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc
    20641 tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata
    20701 tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca
    20761 tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa
    20821 aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc
    20881 aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata
    20941 tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag
    21001 tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata
    21061 caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc
    21121 tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac
    21181 cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat
    21241 ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca
    21301 tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg
    21361 taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac
    21421 gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt
    21481 atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag
    21541 tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct actgt
//
LOCUS       DAPBBR010000045        20362 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPBBR010000045 DAPBBR010000000
VERSION     DAPBBR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.047"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            292..1431
                     /locus_tag="RD488_001941"
     CDS             292..1431
                     /locus_tag="RD488_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDT7658010.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="RD488_001942"
     CDS             complement(1498..2073)
                     /locus_tag="RD488_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7658011.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="RD488_001943"
     CDS             complement(2078..3052)
                     /locus_tag="RD488_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDT7658012.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3335..4303
                     /locus_tag="RD488_001944"
     CDS             3335..4303
                     /locus_tag="RD488_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7658013.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4416..4694
                     /locus_tag="RD488_001945"
     CDS             4416..4694
                     /locus_tag="RD488_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7658014.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4812..5048
                     /gene="secG"
                     /locus_tag="RD488_001946"
     CDS             4812..5048
                     /gene="secG"
                     /locus_tag="RD488_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDT7658015.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5151..5906
                     /locus_tag="RD488_001947"
     CDS             5151..5906
                     /locus_tag="RD488_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7658016.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5909..8266
                     /gene="rnr"
                     /locus_tag="RD488_001948"
     CDS             5909..8266
                     /gene="rnr"
                     /locus_tag="RD488_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDT7658017.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8288..8752
                     /gene="smpB"
                     /locus_tag="RD488_001949"
     CDS             8288..8752
                     /gene="smpB"
                     /locus_tag="RD488_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDT7658018.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9054..9773
                     /gene="atpB"
                     /locus_tag="RD488_001950"
     CDS             9054..9773
                     /gene="atpB"
                     /locus_tag="RD488_001950"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDT7658019.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9826..10041
                     /gene="atpE"
                     /locus_tag="RD488_001951"
     CDS             9826..10041
                     /gene="atpE"
                     /locus_tag="RD488_001951"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDT7658020.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10132..10656
                     /gene="atpF"
                     /locus_tag="RD488_001952"
     CDS             10132..10656
                     /gene="atpF"
                     /locus_tag="RD488_001952"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDT7658021.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10643..11185
                     /locus_tag="RD488_001953"
     CDS             10643..11185
                     /locus_tag="RD488_001953"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDT7658022.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11208..12764
                     /locus_tag="RD488_001954"
     CDS             11208..12764
                     /locus_tag="RD488_001954"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDT7658023.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12778..13680
                     /locus_tag="RD488_001955"
     CDS             12778..13680
                     /locus_tag="RD488_001955"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDT7658024.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13703..15109
                     /gene="atpD"
                     /locus_tag="RD488_001956"
     CDS             13703..15109
                     /gene="atpD"
                     /locus_tag="RD488_001956"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDT7658025.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15123..15545
                     /locus_tag="RD488_001957"
     CDS             15123..15545
                     /locus_tag="RD488_001957"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDT7658026.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16014..16244
                     /locus_tag="RD488_001958"
     CDS             16014..16244
                     /locus_tag="RD488_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDT7658027.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16341..17642
                     /gene="murA"
                     /locus_tag="RD488_001959"
     CDS             16341..17642
                     /gene="murA"
                     /locus_tag="RD488_001959"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7658028.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17655..17831
                     /locus_tag="RD488_001960"
     CDS             17655..17831
                     /locus_tag="RD488_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7658029.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17966..18262
                     /gene="yidD"
                     /locus_tag="RD488_001961"
     CDS             17966..18262
                     /gene="yidD"
                     /locus_tag="RD488_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDT7658030.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18326..18709
                     /locus_tag="RD488_001962"
     CDS             18326..18709
                     /locus_tag="RD488_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658031.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18878..19762
                     /locus_tag="RD488_001963"
     CDS             18878..19762
                     /locus_tag="RD488_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7658032.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19876..20112
                     /locus_tag="RD488_001964"
     CDS             19876..20112
                     /locus_tag="RD488_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HDT7658033.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20200..20280
                     /locus_tag="RD488_001965"
     tRNA            20200..20280
                     /locus_tag="RD488_001965"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20234..20236,aa:Tyr,seq:gta)
     gene            20287..20358
                     /locus_tag="RD488_001966"
     tRNA            20287..20358
                     /locus_tag="RD488_001966"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20319..20321,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4426 g         5611 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcagta ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actttaagta aatgatacaa tgaaaaagaa
     3241 atggaattta cgtgtgccga agaaaaagaa tcctattgat cggtatattg tataataaat
     3301 agattatagt ttggcagaaa gcggcgggtg tacgatggtt attttttatt tcattcttat
     3361 tctgatattt ataggaatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     3421 aagagcgggg gtacagagag gctatgactg gtatgaagaa actgggcacc gcttgatgga
     3481 tcctgctgca gtcacgtcag tagaaaaaaa gcgacaaaaa ttagaagaag agtgtgaaag
     3541 cttctgggaa caaggaatac cgaaaacgat caaaagttat gacgggttga aactagctgg
     3601 acagatgttc ctccaaccaa ctcagcagaa taaatgggtc atttgtgtac atgattatcg
     3661 aagtacaggg aaaagagata tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     3721 cgttcttata cccgatttac gtgcgcatgg agaaagtgaa ggagaaatca tcggaatggg
     3781 atggctagac cggctagatt taattgcatg gatccaactc atcttagatg aacaaccaga
     3841 tgcatccatt attttgcacg gcagttcgat gggcgcttct actattatga tggcaagtgg
     3901 tgaaaagctt ccatctgcag tcaaaggatt tatcttagac agcggatatg tttctgttta
     3961 tgcggaattt cggtatatgt taagtaaaat cacggtcttt cctaaaaaaa tgatcatgag
     4021 atatgcgaat cactatgctc agaaatacgc aggttattct ttaaagcaag catcagctac
     4081 aagacagctt ggtagtaacc atttgccttt gttagtcatc catggtgaaa gagatcattt
     4141 tgttcctaca gaagcagcat acacgattca aaacgctacg gcaggggata aagcattact
     4201 gcttgttcca gaagcagaac atttggaagc atcgatgaaa gatccgaaaa cctattggac
     4261 agtgattttt tcatttattg aacaaagaat aacgatggat tgattttctc ttcctttttg
     4321 taagcaacac gaggataaat aattgtttat agaccatgag actgttaaaa taaggtagga
     4381 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagag gaaaaaaatc
     4441 gtcttgcttt attcaatgat gagcaacaag aaatcggaga aatgacatgg tcggatgcgg
     4501 ggccagacat catgatcatt gaccatacat ttgtcgatcc agcatatcgt ggtcaaaaat
     4561 tagctgaaaa gctagtgtat actggagtag aactagcaag acgagagggg aaaaagatta
     4621 tcccttcatg cccttacgca aaaaaagagt ttgagaagaa accagagtat catgacgtct
     4681 tacgccaatc ataataataa cagctgaaag atttgcactt tcagctgttt ttccatttat
     4741 atagagttgt cacggagttt tatctatgat aaagttaaag agacgatatc ttttgggaag
     4801 gaggctgcta tatgtataat ttaattttgg gaatcgtgat cgttttatcg attgttatgg
     4861 tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca tttaccggcg
     4921 gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc atgcagcgat
     4981 caactgcagt catgggagct gtctggatga tcttattatt tgtcctagca tttttatctt
     5041 cgaagtagtc gaataagcct ctcgcacaac ggcgggcggc tttttttatt gcaaagagaa
     5101 cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag gtgaaacgag
     5161 tgaaacaatt accaaaaccc ctttatgcaa aacatggaaa acgagcagtt ttgctgcttc
     5221 atgcgtactc aggaagtcca aatgatgtcc ggatgctcgc acggttttta gaaaaagcag
     5281 attatacagt ctatgcgccg ctatttaaag gacatggaac gatggagcca tatgatatct
     5341 tgcaagaaaa agcagaaagc tggtgggcag atactaaaaa agctatccat tttttacagt
     5401 ctgaacagtt ttctgatatt gccgtattgg gattatcgat gggtggcatc tttgctgtac
     5461 gggcactaga agaagaatca gtaattggcg gcggtttttt ctgttcgccc ctgtctcctg
     5521 tagaaacaaa cgtgcctgaa aattttgaaa aatatgtacg tcaagtgctg aagatagcag
     5581 gcaaatcaga aaaagaaatc aatgaaaaag ctgtgtctta ccgctcgtta gctgaacatc
     5641 aattaatgga tatacaagac caagcagcaa tcgcagaaag tagactatca gatatccaac
     5701 agccaatatt tttagctcaa gctgggaaag atgaaatgat cgacccaaat ggtgtatttg
     5761 aaacggcacg caaattgagc cgccaacgag tgacacttca atggtatcct gaaagcggtc
     5821 atgtgattac agttggcaca gcaagacgcg aattagaaaa agacgtgttg gaatttttag
     5881 aaaaattacc ttggaatgag gaataaatat gacaaaagaa acaataaaag agaaaattct
     5941 ctttttcatg gaaagcagtc gcaaacgtag tttttctatg gaagaaatcg ctgaaggtct
     6001 aggctttcaa aaaagcgatg attttaaatt actagtacaa acgattgctc aaatggaaag
     6061 agaacagagt atcgttttca ataaaaaagg aaaagtcaaa cttcctttaa aaccgatctt
     6121 ggtcgaaggg acatttcggg caaatgaacg aggatttgga tttgtaacga ttgatcccga
     6181 agaagatgat atctatatcc cgaaagaagc gactggcttt gcaatggatg gggataccgt
     6241 agcaattgat atcatgaagc gagcaaatac agatatggat cgcggagcag agggaaaagt
     6301 agtggagatt cgagaccgag cgactactca gttagccgga gaatttgttg cttattcaga
     6361 cgaagagata caggaaacgg atctttatgg tgtggtcatc ccgaaagata gaaagcttaa
     6421 ccaattcaaa gtgtatgcag cggcagaggg agttcgtcca gttgacggaa gtattgtatt
     6481 gatcgaactg acccattacc ctgaaaaagg gtatgcaact agtttagaag ggataatcaa
     6541 gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcgattg tcgtggctaa
     6601 cggtattcct acaaaatttc ctgatgatgt gttatctgag gcagatgaag ttccagacca
     6661 gatcagcgaa aaggatattg ttggacgcag agatttaaga gatcagctca tcgttacgat
     6721 tgatggagaa gatgcaaaag atctagatga tgcagtgacg gtcaaaaaat tagaaaatgg
     6781 taattatttt cttggagtac acattgcaga tgtatcttac tatgtgacgc aaggcagtca
     6841 actggacaga gaagcatacg aaagaggaac aagtgtctat ttgaccgatc gagtgattcc
     6901 gatgatccca caacgtttat ccaatggtat ctgttcattg aatccccatg ttccacgact
     6961 caccatgagt tgtgaaatgg agatcgatcc aaatggacaa gttgtctctc atgagatttt
     7021 tccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc aaatcttaga
     7081 agatcaagat gaagaaacga tgcaacgtta tgctcagctc gtgcctatgt tccaagaaat
     7141 gggtgaattg catcgaatcc ttgaaatgat gcgaatcaaa cgtggagcga tttcttttga
     7201 ggatcgtgaa gcgaagatcc ttgttgatgc tgaaggacac ccaaatgata tccagctaag
     7261 aagcagaggg ataggtgaac gcttgatcga atcctttatg cttgctgcca acgaaacggt
     7321 agctgaacat tataataaat taaatcttcc gtttatttat cgaatccatg aacagccaaa
     7381 agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc tggtccgagg
     7441 aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag tagaagacaa
     7501 accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag cacgctattc
     7561 agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact ttacatctcc
     7621 tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca gtgaagataa
     7681 aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag atcatagttc
     7741 taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga agaaagcaga
     7801 attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg ttgtgaaatt
     7861 cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca atgaattgaa
     7921 acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa gaactggtct
     7981 gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc cagatgaacg
     8041 agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac gtccaaaagc
     8101 acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct cagaaaaaaa
     8161 tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga aaaaagggaa
     8221 aaagccattt tacaaaggtg tcaaaaagaa gaaaaagaaa aaataaaatg agttggagga
     8281 aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag ctcgccatga
     8341 ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg agatcaagtc
     8401 gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca acggggaagc
     8461 tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta atcatgatcc
     8521 gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg aaaacgaatt
     8581 gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg gctatgccaa
     8641 ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag atttgaaacg
     8701 aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat aatttcatta
     8761 tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg ttagcattta
     8821 atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg tgcatgggga
     8881 aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga aaatgttttg
     8941 aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg aaaaaaccag
     9001 atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat ggattggatg
     9061 aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt tgtataatgg
     9121 tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga aatcttaagt
     9181 tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt cgaggaatcg
     9241 taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca tttacattgt
     9301 ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc ttacctaacg
     9361 aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact ttggcattta
     9421 taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa ggatatttcg
     9481 taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt gaagaattta
     9541 caaacttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg gaagttttgc
     9601 taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca ttagcaattc
     9661 cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa gcatttgtct
     9721 ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa taatactcgg
     9781 ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa ttatatcgca
     9841 gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg tcaagttatc
     9901 tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt ccgtacaaca
     9961 atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt tatcgccttg
    10021 attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat cgtttgttac
    10081 tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc tatgctgaat
    10141 caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt tgtcagcggc
    10201 tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat cagcgatatt
    10261 ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca atctcgcatc
    10321 aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg ttctgatgca
    10381 gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa tattttgaag
    10441 gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat cactgtagaa
    10501 cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct tcaaatcgcg
    10561 gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat caatcaatac
    10621 attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa gacgttacgg
    10681 gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct atcaagatct
    10741 cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt taagtgatgt
    10801 tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg gttatgatgg
    10861 aatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg accttttgtt
    10921 catgattgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat tgggaagtgt
    10981 cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga atgttgcaaa
    11041 aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta ttattggtgg
    11101 cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc aattagaaaa
    11161 aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg gccatcaaag
    11221 cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac gtgctttcag
    11281 tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca catggtttag
    11341 aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga atggcgcaaa
    11401 acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc attcgtgaag
    11461 gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag gccttgatcg
    11521 gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc gttactgaca
    11581 aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct gttaacgaac
    11641 caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc ggacaacgtg
    11701 aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgattgat acgatcatca
    11761 accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa gattctacag
    11821 ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca atcgttgtga
    11881 atgccggtgc gtctcaacca gcaccattac tttatatcgc accatatgct ggtactgcaa
    11941 tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat gatctttcaa
    12001 aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca ggtcgtgaag
    12061 cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca gcaaaattaa
    12121 gtgatgatct aggcggcggt tcaatgactg ctttgccatt tgttgaaaca caagctggag
    12181 atatctctgc ttatatccca acaaacgtta tctcaatcac tgacggacaa atcttcttag
    12241 aaagcgactt gttctacgcg ggtactcgtc cagcggttga tgccggacta tctgtctctc
    12301 gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact ttacgtctag
    12361 acttagcaag ttatcgtgaa ttagaagcat ttacacaatt cggttctgat ttggatgcgg
    12421 caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa caaaaactgc
    12481 atgcaccgct agctgttgag aaacaagtag tgattttgta tgccttgaca catggattct
    12541 tggacagtat ccctgtagac agtattttag acttcgaaca tgaattattc gaatatctgg
    12601 ataccaatca ttcagatatt tttgaaacaa tccgtacaac aaaagatctt ccagaagaag
    12661 aaacgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca aaaggaaata
    12721 attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt gagatgaatg
    12781 ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac gagccaaatc
    12841 acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc ttcttcacag
    12901 aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac tgctactcag
    12961 ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag catgctgctc
    13021 agccgtcctg tgaagaaaac cggttatatc gtcatcactg cagatggcgg tctggtcggt
    13081 ggatataaca gttcgatatt gaaacaaacg atgtctattt tagaagaaga ccaccaatca
    13141 cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt taaagcacgc
    13201 ggtatcaacc tagcatatga gctgcgcaat ttatctgatc agccaagctt tgatgaagtc
    13261 cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga tgaattatac
    13321 gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga aaaaatgctg
    13381 ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata tatttttgaa
    13441 ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag tttgatctac
    13501 ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc aatgaaaaca
    13561 gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa ccgtgcaaga
    13621 caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc actagaatag
    13681 tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa tcggtcccgt
    13741 tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg cattagttgt
    13801 ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag aattagggga
    13861 cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag gaatggaagt
    13921 cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag gtcgcgtatt
    13981 caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg cggaaagaag
    14041 cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag aaattttgga
    14101 aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga aagtcggact
    14161 attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc ataatatcgc
    14221 ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc gtgaaggtaa
    14281 tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca tggtgttcgg
    14341 acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt tgacgattgc
    14401 ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca acattttccg
    14461 tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt ctgcggttgg
    14521 ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca catctacgaa
    14581 aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact acactgaccc
    14641 ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac gtaaattaac
    14701 agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg ctttagcacc
    14761 tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg tattgcaacg
    14821 atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat ccgatcaaga
    14881 aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa actttaacgt
    14941 ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa cagtgaaagg
    15001 attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt tccgaagtgt
    15061 tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga aaggggtgcc
    15121 ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc tatgatcacc
    15181 atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg cctaaacatg
    15241 caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca gattcagata
    15301 cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat aatgttgttt
    15361 caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt gcggaacgtg
    15421 caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat acgaacgaat
    15481 tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta tctaagcact
    15541 cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag gttatgacag
    15601 aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    15661 aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca gaggttgtga
    15721 aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct catattttgc
    15781 cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg gaataaggga
    15841 ctgcgacaag acttttgtct cagtcccttt ttttgcatat ttttagcatt tatttcctaa
    15901 aaaatgtaag gggattccta tatttttaag tatacttgtt tttcctttta tacattttat
    15961 ggtattatca ttttattagt tattataaaa caatcgttag aaaggacgtc attatgcaag
    16021 tatacggaat tgatgcggtg cttcgaatcg tgagtcattt ggcgtttatc tacttagcct
    16081 tctggtcttt acgttcgtta cgcattgaaa cttttttcag accaatgcat aatacgcaaa
    16141 ttagaatggc aatcgtactt ttttcaattt ttttagggta cactgcaagt aattttttct
    16201 tagaagttat cgctttatgc cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta
    16261 ctattttaaa agcaaggatg ttataataga aaagattttg agtaagtgta tgctcattgg
    16321 aattttttgg agggaacaac atggaagaga tcatcgtaag aggtggcaat caattaaatg
    16381 gaacagtaag aattgaagga gctaaaaatg ctgttttgcc tattttagct gctagtttgt
    16441 tagcagaaga aggtattacg acattagaca acgttccgat tctttctgat gtcttcacta
    16501 tgaatcaagt gattcgtcac ttaaacgtag atgtagattt tgatgaacaa aagaatcaag
    16561 taacaatcga cgcttcaaga caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa
    16621 tgcgtgcttc aatcgttgtg atgggtccgc tacttgccag aaatggacat gcaaaagtag
    16681 ctatgcctgg tggatgtgcg attggtaaac gaccaatcga tttgcattta aaaggatttc
    16741 aagctttagg agcaaaaatt attcaaaaaa acggctatat cgaagcaatt gcggatgaat
    16801 tgatcggtaa cacgatttat ttagatttcc ctagtgtggg tgctactcaa aatatcatga
    16861 tggctgccgt aaaagcaaaa ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa
    16921 tcgttgattt agcaaacatt ttgaataaaa tgggcgctca agtctatgga gctggtactg
    16981 aaacaatgcg tattgaaggc gtggatcatt tacatgcagt caaccactca atcgtacaag
    17041 atcgtatcga agcaggtacc tttatggttg ctgctgcaat gacacaaggc aatgtgctga
    17101 ttgcagatgc tatctctgaa cataactgcc cattgatttc taaattgatc gaaatgggtg
    17161 cagaaatcat tgaagaagaa ggcggagtcc gtgtcatcgg accaaaacat atcttaccta
    17221 cagatgtaaa aacgatgcct catcctggtt tccctacaga tatgcaagct caaatgacag
    17281 ctatccaatt agttgcagaa ggtacaagtg tggtgactga aacagtgttt gaaaatcgtt
    17341 tccaacattt agaagagatg cgccgtatga acgctcatgt caaaatcgac ggaaatgtag
    17401 caatcatgga tggaaaccat gaattgcaag gtgcagaagt atatgcaaca gacttgcggg
    17461 cagcagcagc attagtttta gctggcttga aagcaaatgg aatcacacgt gtgcgtaact
    17521 tgaattatct agaccgtgga tattataatt tccatatcaa actacagcaa ttaggtgcag
    17581 acgtcgaacg tgtagacatg gatcaaactt ctgctgaaaa aacagcacaa acgattgctt
    17641 aaggaagtgg ctgaatgagt aaccaacgat atatcttatt aactttgata aagattttag
    17701 tggtgatctt attgcttatc cttctttttg tggccggaac gatgatcgga tatggtgtca
    17761 tcggtggcgg caatccattt aaagtattcc agccaagttt gtggattcat attcgagact
    17821 tttttcattg ataaataaga atcacagtgg ttctagtcga tatgaagtga gccatgaagc
    17881 agaacatgat aaaagaaaac agaagggaac gttgacgtta gtcgcgatcc ctttttttag
    17941 taaaagaaaa gaaggaatct aattgatgaa gaagatattg atttatttag ttagaggata
    18001 tcagcgcttt atttcgcctg catttccacc tagctgccgt tattacccaa cctgttccaa
    18061 ttatatgata aaagcaattc aaacccatgg tgcgctaaaa gggacggtaa tggggactgc
    18121 acggatctta cgctgtcatc cttttgtcaa aggcggtatc gattatgtac cattgacatt
    18181 ccgattaacg cgaaataaga aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa
    18241 tacgggtagc actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg
    18301 caactactta tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg
    18361 gtccttgtta ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg
    18421 gagtggctgg atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag
    18481 ggaaaaagaa tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat
    18541 tggcggaaaa ttacttgaga cagcttttca gaagctttca cagctagctt caaaccaaac
    18601 tcggatcatt atacgtactg gcactactag tagcgctgcg ttacacctct atcaaaaaat
    18661 gggctatgtg gagattggtc gagtcaaaga ctattttatc catcattaat ctgagcccat
    18721 ttttgaaaat ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa
    18781 tagctttaac taataaactt tcaattcgag aaaatgcttt caaatgctaa atagatacat
    18841 tacaatagct ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt
    18901 tggtggatcg gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca
    18961 atttgcaacg cctgaatctt gggaagaaat gaaaacgcaa ttatttcaag tttataaaaa
    19021 aatactcgtt tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa
    19081 tgagaaacag gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt
    19141 ccgagatttg gaaactctgt ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc
    19201 cggaatggct gaattttatg aaggtgctgc ccgtgattat caagatgttg cttttgttgt
    19261 ggcaggaact gggattggcg gggcgttgtt cacgaaagga caaataaata aaggggcaca
    19321 tctttacggt ggagaatttg ggttgatgtt cttagatggc gataagacat tcagtaaact
    19381 tggtacagcg gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc
    19441 ttataccgga aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga
    19501 agttgagagt ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga
    19561 tccagaagtg atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat
    19621 caaaagccga atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat
    19681 tttattatgt gagtacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc
    19741 tgtacgtcaa ggagagaatt aagagcttta gagaaggtgc agcttgcata aaagaagaga
    19801 atgaaatgaa taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat
    19861 atctgagagg tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa
    19921 gtgaaaaaag atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa
    19981 atgattggtg agatcttagc ctatgggcca aaagaatatg aaattttctt tggtgaagaa
    20041 gattttggaa aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat
    20101 ctgcacgaat aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa
    20161 ttaggtatta taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta
    20221 aacgcgacgg actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca
    20281 tttcattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    20341 cgaatccagc taccccagta ta
//
LOCUS       DAPBBR010000046        18974 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPBBR010000046 DAPBBR010000000
VERSION     DAPBBR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.048"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..176)
                     /locus_tag="RD488_001967"
     CDS             complement(<1..176)
                     /locus_tag="RD488_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658034.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARV"
     gene            complement(343..2313)
                     /locus_tag="RD488_001968"
     CDS             complement(343..2313)
                     /locus_tag="RD488_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658035.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2328..3194)
                     /locus_tag="RD488_001969"
     CDS             complement(2328..3194)
                     /locus_tag="RD488_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658036.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3184..3417)
                     /locus_tag="RD488_001970"
     CDS             complement(3184..3417)
                     /locus_tag="RD488_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7658037.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3429..5585)
                     /locus_tag="RD488_001971"
     CDS             complement(3429..5585)
                     /locus_tag="RD488_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658038.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(5605..5826)
                     /locus_tag="RD488_001972"
     CDS             complement(5605..5826)
                     /locus_tag="RD488_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658039.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            complement(5936..6274)
                     /locus_tag="RD488_001973"
     CDS             complement(5936..6274)
                     /locus_tag="RD488_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658040.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            complement(6674..10315)
                     /locus_tag="RD488_001974"
     CDS             complement(6674..10315)
                     /locus_tag="RD488_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658041.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPAPDN
                     QENNQETVINKSVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(10318..12267)
                     /locus_tag="RD488_001975"
     CDS             complement(10318..12267)
                     /locus_tag="RD488_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDT7658042.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(12309..13367)
                     /locus_tag="RD488_001976"
     CDS             complement(12309..13367)
                     /locus_tag="RD488_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HDT7658043.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(13486..13941)
                     /locus_tag="RD488_001977"
     CDS             complement(13486..13941)
                     /locus_tag="RD488_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658044.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(14525..15328)
                     /locus_tag="RD488_001978"
     CDS             complement(14525..15328)
                     /locus_tag="RD488_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7658045.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            16308..17531
                     /locus_tag="RD488_001979"
     CDS             16308..17531
                     /locus_tag="RD488_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDT7658046.1"
                     /translation="MESYQFQIFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            17566..18333
                     /locus_tag="RD488_001980"
     CDS             17566..18333
                     /locus_tag="RD488_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7658047.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            18525..18923
                     /locus_tag="RD488_001981"
     CDS             18525..18923
                     /locus_tag="RD488_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDT7658048.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT         5736 a         3620 c         2748 g         6870 t
ORIGIN      
        1 aaaactctcg ctttttcttc atcagtaaag tttttataca actgattaca ataatgaggt
       61 ttttgaagtt tctgaatacc tatactaact tcaaatcctt cttcatgttg aattaggatt
      121 acttctgtgt ctctacctag aaatattcga tctaaaattt ttatgtttgg tttcattatt
      181 taacctccac tataattatt tcactcaata aggtttcact ttatgaaatt tctatagttc
      241 tcttttcaca aaacgtacca tgttctctaa gactgttttt agtctcaaat atacatgttt
      301 tttcttatcc tttccttata cactcaaaat caaagataaa acttaaagaa taaactctcc
      361 aataacaaaa ttattagtca gatccactgg tctcctgatc tgaaatttat tacttcttcc
      421 tgttgtcaaa tactgtctca aatcaacaga aagtttttga tcatcttctc cttttctagc
      481 aggagcaact tttttttcat acttcattaa ctctccactg gtcatctttc caatgatagt
      541 gtaattaaaa tcactttcaa aactttggta aatttttcca tctgtattga atatatcagc
      601 tgtttcaata tcttctttgt attcattgtc ttctcctgaa ccgattgtat caaatagaaa
      661 ggcaagacga attccatctt cttcaagcat tgttaatctt tttttaatta gcccaacggt
      721 ttcaatagat aacttatcga agccgtgaat cataacaata tcatcttttt ttgcttgtga
      781 tgtgatgaaa tcaaaggtat ttaaaaattg agcttccata acattggttt ctgctcttag
      841 atcacctaag ttatagtaaa actgtaattt gtcactttta ccgatttctt tcagtgtcgt
      901 tctttgatta aacatcctag agaagctgtc taatgctgtt ctcaatgtgt cttttaatac
      961 aataatacga tcgacttctt tttcagtacc agattttttg gcttttgttt cagcattagt
     1021 caaatagcta ataaaatccc caagaactgg cattgtatca ctactgttca ccaaaagttt
     1081 tgaacgttct tcataattaa tatcccaaag tttctgactt atataaaagt tacctaattc
     1141 ttttttcaat aaaactctag ttgcagaatc taatgttctg cctgctaaca aataaaaaat
     1201 ctgagttagt ttatcgagat tccgtctata taaatcacca atgtcctttt gattaccaaa
     1261 aagctccaaa gagttaagac cttcttcagc caaattaacc ttttctatta cactgtttaa
     1321 cgaaggtttg gcaacaaatg ttctaccagt tggatcacca aagtaatcaa atttatttaa
     1381 gacaatatga aaagttcgtt tatgatttgc cattgcatta ttagcaatca attgccccca
     1441 aagtgatgat gctgagattt tttcatcata gcctttaatt gtagcgtttt tgtgtgatgc
     1501 cactaaaact ttacttgtaa aagaatcatc cagtgccata aaagctacac cacttgcgta
     1561 gctagtagac atagtgccga tagcccatcc attcgcatca tctaaacctt tgcgaattgc
     1621 atgatcattt cctgcaaaat ccgaactcat agacgtatac tcatagacat tcccgattgg
     1681 ttcacttaaa agtctatcaa acagatcacg ttgatctcct ccatatgaca taagctttaa
     1741 tccatacatt ttttcatcat acaaccgttg gagtttaatt agctgttcgc tgattttatt
     1801 aggagaatcg gatactaata ggatttctag cttccaatca ataattttat ttgccatgct
     1861 gtctagtaaa gatgctgtat tcaaatccat aatccgcata acagttttgc taatttcagc
     1921 atctgaattt tttccttcta aattattttc ataactattc gttgatcccc caacattctc
     1981 gtgcattatt tcttgttgat ctttttgtga cactggctta tctgcttcaa ttagataggc
     2041 ttttacccct tctactctca cttcaggaat agctttaacc atccaaccaa atccataatt
     2101 tctattcatt ccataagtat tcactaattt cacaattgtt ccccaccgct tacctgtcct
     2161 aatgtaagat ggtgtaaatt gataaccaac taaagatgtt aaatcactaa caaaggtatt
     2221 attcactacc tttgaatttc tagttttttg ttctttttta gtttttctct tttttttgaa
     2281 atttaatagt tgtgatctac ccataatttc catttaatct ctcacctcta tttcagtgca
     2341 taaatatcag ataatatttc ttttgtttgt ttagctgaca actgagtgac actataataa
     2401 agtcctctac tcgtatagtt ttctaaacgt tccacacctt catccaatac catcttagat
     2461 tgagatttca agataagata ttggattact gttgttttca caccatcaat atattctgat
     2521 acaaatcgtt cttgctgatc tattatgtca aagactgctt tgttactcct tgcatttcgt
     2581 ttttgtattt tcatatttcg agtttgtctt tccgtattct gaggttgaga tgaagtgatt
     2641 ttgatttcag ctaaggaacg atctctggta ttttgatatt gtattgattt cgattcctga
     2701 gccataactt cttctggaaa agcggttagt gatgtagccc catctagatt gaacattaat
     2761 gctacactcc catctcgata tacgattgtt ccatcttgtt tcacttttaa aatctctgtg
     2821 cctcgaaatg gtttcttttt ccccatagat actcttgctg aattaactac tgatttgaac
     2881 agtctaatag aaccagaaat caatgaacca ctagatggat caataaacat atactggcta
     2941 attagaataa gaaatccaat tatcattaat aacgttggaa caaaaataaa tttcagttta
     3001 atcgtatcag aaactaagta aacaattgat ccaagaacaa cgactgcaac aactatagct
     3061 gatacaatta atctttttgc tgtaacagaa taggtgctat tgacatgctt ttcaagccat
     3121 tcaactctga caattgtttc agaaggtttt tgatgtaagt tatgtttaaa tccatagttt
     3181 gagttatctg ccatcagaaa tacttccttt cacgttcaac ttacggtaaa cacctacagt
     3241 tatcactatt gcaacaataa gcaagccaat taaagatatt gacttgctca ttgtctcgtt
     3301 cgtttgtggt agttcattta cctgatacac gagctgtgct tcctgtaagt gctgagaaga
     3361 ggtcatgttt tcttgattgt tttgaattac tggataaact attttttctt ctcgcataat
     3421 agccctcctt agttattatc agataagtga gcttgaattt tgtactgatt tccgtctgga
     3481 gttttcacaa ctgctttttc tccatcaata gaaatcactt cagccttagt tgttttccca
     3541 tcaatactga tgacaacatc tttcccaact ttgaactctg tagttggtgt tgcttcatag
     3601 ctactatttg ttgaagcaga gttcgtattt gtcccaatcg aattttccac tctcgaaata
     3661 gatgtttgag tttgagcctg tgcttgttga ttattatgac taataaagta ggacgatccc
     3721 aagatcgttc cgcaagccat tgcagcgaca gaaatgatag tagccatctt tttacttgta
     3781 aaatcacgtt ttgaacttga ttgattttct gtagcaactg ctaatgattt cgttttttct
     3841 gccatttgag ctagatcact tcgggaacga gataagtctt ctcttaaagc ttcactttgt
     3901 tctgccaact tttcgctatt taatttataa ccctctgcta aatctttgac ctctttcatt
     3961 cgatctttat attcttcgat agttttttgt tgctctacaa gttttgtttc taattctttc
     4021 gtgttgttag ctacctgctt ttcaacttct tctttgttcg caaaatattt gacaaccaca
     4081 tctgttgttt tctcttttgt atcatggaac tcagcttcat tttctgactt tgttttttcg
     4141 acaatctcta aagttttttc ttgcacgtct gttaatgatt tttcaatttc tggtttcaat
     4201 gaattgataa ttcgttccac cacaacttct tttgcttctt ggctttgttt caatgcatcg
     4261 tttttaatag attcaattgc ttcttggtac tgttgatcaa gactttcttc agttgctttt
     4321 ctatattcat cttcttgttg tttaacttct ggtaaatgct cagcatcata ccgttgctct
     4381 agtttcttta gttcagcatc caaataagcc tgtttcgcca tatcataatc tttacgaatg
     4441 atattggatt tttccatcac taaatcatca attttagatg cttctgcttc gtagctctct
     4501 ttagcaaccg atagtgtatt tgtaaactga ttttgaccat ttaatgaggt tgcttcctct
     4561 atccgcaaaa gctcatcagc taacatttgc tttcctttga ggatcaattg ctccttcgtc
     4621 ttatttaatt cactgttgat tttattatta gcaatagaga tgcgagcgtt catactctct
     4681 ttagctaaaa acagcaatgg tttcaactca ggtatggata gcatctcctc gtttaaatcg
     4741 acagggtcat taatctcatc taaaactaca ggttgaaatt tgtcagcaat gatctgttca
     4801 aaattttttt ctaaaaaatc agcatctaag tttttcggta catcactttc agatgtgatt
     4861 ttttcagctt cataaacata attttctttg tcactttggg attcgggttt ttcatcaatt
     4921 tttggttgtt ggtaggtttc tgtttgtatt tgtgtttctt ctatgcttac ttcttggttt
     4981 tctgcttcgg ttggtttgtt atcatccaca aaaagagctt ctttttcatc tggtacattt
     5041 tctgctacgg cttcaaattc aacttcttca gaagagttga aggtctcagc aattcgttct
     5101 aatccattag tagctacttc taattgctct actgcgctat agaagtctgt agcttcttca
     5161 acttctgatt caaacacatt aggatcatcc ggaataacta ataattgacc actactatcc
     5221 ataaaacgga cacctgctaa tagcttctct ttaaattttt ctggtagatc agctacataa
     5281 ttcaaacttg acttcaatag aacgacatac ttctcagaat cgagaatagc atcatcctca
     5341 tctataactc cctcactgtt gagcttttgt acatcttcaa ttaccatata atttttcttt
     5401 ggtaaatctt tggtcagcaa cgcatcgaat tctttccata cctttgcttt agcttttttt
     5461 gccttcgctt ctttttcttc ttttttgtac acttcgagta attgtggctt caaagagagt
     5521 gcaactacag gaactgtttc tgccacataa ttaatagatt cggtaatatc tttgaatttt
     5581 gccattattg taaaactcct tttttcagtc aatagttctt ttctgtttat ctagcatata
     5641 tacatatgct ttttcgaatt taataagcgt ttcaagtctg gctttttcaa tctttttact
     5701 cccatttcga taatcataga actggttaac attcatattc attatctttg ccagttcggt
     5761 acctttcaga ctgctcatta atacttcgtt ggcgtgagct aacatttttt ctctatcaaa
     5821 aaccatctta catttacttt cttccctcac ttctaaacta cgcttggagc gtagtttttt
     5881 ggtaaaaagt aaattgaaca aatcggcata ttatccaaat ttgttcaatt cacttttaac
     5941 ctaacagttc attttttgga aattttgaaa ctagatagat accaacaact ggaataagtg
     6001 ctgatatgat attagctttt tggttcaaat cattacctgt tttagtaccc attgtgtaaa
     6061 gcataacggt tgtaattaca ggaataataa agattgcaat aatcgcccca acatatttta
     6121 atccatctcc ccattttgca tcaccaaaaa atttcattgc agtgaatcct ggtttcaacg
     6181 aaaaaacgaa tgccaagaaa tacaaaacaa cttgtactaa agttttcata tcaggcgtca
     6241 ttccgctaac caaattttta atagaatcga acatataaaa acctcctttt taatattttt
     6301 aataagttaa ttatatcatc gacaaatctt atttgttcac ttgtcaatga tctaactaag
     6361 aaaaagacgt ctcgatattt acatctttat gttatcataa taacataaat tttcgatgat
     6421 taaaagagat tttccattaa attatttcac tttttttatt ggctaaaaat gctggtttat
     6481 caagtttttg tttagataat aattctgttc tttaccagca taagcccttt ttaattatac
     6541 aactttgaac agtaaatatt taattcattt atagacaatt taaaataatt tttttgcata
     6601 aatagaaatt ttccttgaca tcttcagtta gaaatcaaag taaaaagaag gagcaaatca
     6661 atgctccttc tttttactcg tcttcagact tattttcagt tgatttttga ttaccgtatt
     6721 ttacaatata gtccttgact gacatggtag atttcttcac tactttacca gttttggatg
     6781 ctcctgtagc agtagccttg gcaaccttag ccgttccttt acctatttta atagcttcgt
     6841 ttttagcttc ataggttatc cctgctagac taccttttgg agcttttgct aaagctttat
     6901 ctgctgaggt gtaaacattt ttaccagttt ttgatagata ttcaacggct gatttagctg
     6961 ttgatgtttt cttggttgat tgattagatt tccctgaatt atctgaagta gatttagaat
     7021 tatttgttct attattttta tttgtcagtt caggttctct aattgattga ttgtctttcg
     7081 acattcctga tccaatattt gtttcatatt tatctgtttg attaacatta ggagtaggaa
     7141 tgaacttttt cttcacatct gattgttctt tatccgtttc ttttgttagc gattctctgt
     7201 ctttaagtac tgtgtcattc cgaatagcac tattatcaaa gttgctgtta agctctcttg
     7261 actgactttc accagatgct ccatctccta attcccgatg cactctgtct gacacgtcct
     7321 caccactcat ttcattcctc agttcttgat gagtttgatc taaagtaatc tcgtcttctt
     7381 cattctcagg aattgcaaca gcaattggcg tatgccgttg ttgttcgagt tctctatttc
     7441 gatctgccac aagcgcatct ctcgtctcaa tgatattccc atcctcatcg actaaatctc
     7501 cattcacatt atatccatcg ctgtgtttac caagtttatt accaaactca tcaacaagat
     7561 ttccatcttc atcaactaaa cgaccttttt cgtcaactaa acgtccgtta ctatcatgac
     7621 caaaatcacc atttagcaac ctgcgtccat tttcgtcaac aagatttcca tcttcatcga
     7681 ctaagcgacc tttttcatca attaaacgtc cttcgctatc cataccaata ttaccatctt
     7741 cactatcttc caatggttta ccattagtat ctataaggtt tccatcttca tcgaccaaac
     7801 gccctttttc gtcaataaag ttgcctttag catctttacc gtatttacta tcttttaata
     7861 tttcaccatt ttcatcgaca aagtttccgt tttcatcaac catacgtcct aaatgatcaa
     7921 tatattgttg ggagttatta cgtagttgat cttgacgaac taaatctttg aaagaggtat
     7981 tattgattgt ggaaccaact ccgccaccgt tgaatgacat tccttctggt gtttcaggaa
     8041 ttactttatc agcaatggac ttagcatcag cattgctatc tcccatattg ttcaaacgtt
     8101 cagccatttt ttgcgctcca actgctccaa gacctcctgc aaccatatct tttactgagc
     8161 tgttgccacc atcataatag ggatttttag ctccttggct tttcttgatt gctttagaaa
     8221 cgccgtccac aactcgcaca gcatcatttc tattaccaaa taataactta gcacgttcat
     8281 caaacccaaa cgctacttca agtggtaagc caataagcat attaatcaaa ttatttactt
     8341 tttcgccttt tttaaagact aaaagatatc ctacacctaa aatcatagca gatcgaacaa
     8401 tatttgctac gccatcgcca actaatgtat taggaatgaa tcccacagca gtatcaccaa
     8461 atgcacgaat aaaagtaatc agaaagatag gtaattgtag tccgatcaga gatgttgtaa
     8521 caacacctaa tgaaattgcc atcacacctg ctcctgatgc aagtgatcct gttagaacta
     8581 cttcccaaat ccgaataaat tcacgtttaa atgctttcac gatattcaca ttgaacatcg
     8641 cccaagcaca tgctaagtaa agaactgcta aaacgattga ttcagcgttc atcgctagcc
     8701 acgagccaaa cttacccatc gctccatgac caactaagga tgctgtacgc cattctgttt
     8761 ttactgttga catattctta gcactgcctt gaattcctga aggagcgata ttatacgcat
     8821 aaaacttagc tcctgatgta tcaagtgccg attggagcaa taaagctacc gactgtgtgc
     8881 taaaagttgc attgttagca acgccccaag gttgagtagc atcaaagtta tgcgctgttc
     8941 cttttccatc aggcttgcga ttgtcgtctg tcacattttg atttgctgac caaatatatc
     9001 catttaaatt ggttggtttc ttaattgcac ttccttcttt tccatcccct aaattatagc
     9061 ctgtccaaac agcaggcgct cttcccatat aagcatcatt ttcggcgaca ttaacatcac
     9121 cggcataagt attaatattg aaagtatcat tcgatgacca ttcttttaat agagccatac
     9181 cgactgaatt agaatctaga tcattatttt gtctggcata actgctagta ttgatcgctc
     9241 ttatcattgc agatttttta gatggttcat aatctgtatc aacgaacttg atttcggatg
     9301 taggctttcc gtcaggtaca tcaccaccag tatcagatga tggagcaaga ttttgagtag
     9361 aagcccaaag tcttgtgtta atgatgtagt cagaaacaac atttgttggt atatctccat
     9421 ctttttttgc tgactggatg ccgttgatat aaactcccaa tagcgatcct gccactggta
     9481 agaatataaa caatacaaaa atacgaacaa tccatttttc aagtactggt gataatccct
     9541 tcgagttaac accatctttc gacaataatt tcattccttg ataacctagt attgctgtga
     9601 aaaagagcat agataagctt gctatcgctt taaataattc attatttaat cccaaattgt
     9661 taagcaagct agttaatgct ttagataccg gattagatac atccgatcca ccttctcccc
     9721 accccataag agaaaatata ttcatactca tgaaaaattt tccaaggagt tcatttatgg
     9781 attcagcaat attagaaagg attaaactaa ttgatccgat aaaactacca atcgtcctac
     9841 caatacttcc tagaatggat gatgcttgac tggcaatagc atttcctgag actgtttcaa
     9901 tatatccata gtaactataa gttgctagag tagatgctag ttgtgtacct gcattccccc
     9961 ctgcaatcga attaccttgt ttagaaatat cagaataagg aaaatcagca ctgataccac
    10021 cttgtcctaa caaattcatt tgtccagttt tagcagcact atcattgact tctttatctc
    10081 ccatcaagat acgagcatat agtgtccaca tcccttgttc tgccggttta ctttccgcat
    10141 aagcaacgct cttatttata actgtttctt gattgttttc ttgattgtca ggagctggat
    10201 cattcattcc aaatggagcg cctaaagtta ctgctaatac ccctccaata actagacctc
    10261 ttacgaccca tcgttttatt ctaaggtttt gtagtaaata tttcttgaat ttcatagcta
    10321 cgcccctcca atcgaaaata caatcttgtt ttctttactt tcagcaacgg aaggctttgc
    10381 aataatttca gcattagaat caccttttcc ttcaaacgct ccagcttcac tcaacttaac
    10441 atcgaatatt tttgcgtttg gataagtaat tattgcttca gtaatcgctt cttcaaactc
    10501 agattcaact aaatgcaaga tattccttgc accccctgat ttagaatcct cttgtgaagc
    10561 catgtcaaaa actaagtgca tggagagatc gtctgcataa aaattttgac catatactct
    10621 ttctttccta ggtggaagac gtaagtctat atttaaatgt tttcgtacta attcagcact
    10681 cttcaacatt tcattataag caatttccag aagagtttgt tcggataaag cccaaaatgg
    10741 aactattcgt ccaaatcggt taataacttc aggctttaga ccttcaccaa tcaaggcttg
    10801 tttgatccct gatgcgactt ttcggtattc tctttttagt tcagtgctgt attcattaga
    10861 attttccttg tttgtaacac gagatagtga gctatatcgg tttaacgaat cgaacatctc
    10921 cgcacctgca tttgttgtcg caaataaaat tgtatttgac aatgaaacgg tgtcgtgaac
    10981 ttctcgatca tcccatcctc tttcagtaaa acttatccta ccttcatcta aaattgataa
    11041 aaaggcatcg agtgtttcta caccagcttt ctcatattca tcacacacaa taatcgcaga
    11101 aggatcatgc cttacatgag tacctatgag tcgtctaaaa cgcattgcat catctttggt
    11161 tttgtaatcc ggcatattaa ctaagagaac tttattttca tcgccataaa gtcctcttgc
    11221 cacggcttta gccattgcag ttttaccgac ccctgttgat cctgtaaaca gagcagttgc
    11281 ttttggttgc tttcgacctt taaaacgatc aaatccaagc ttcatacgtt taaacaacat
    11341 tgttatagta taaactgcta acggttgtcc ttttatggac tttaattcct cttgaagttt
    11401 ttccatatca aaatcagaat ctagctgaat attatactta ccaaatattt gcaatagact
    11461 ttctcgatta taagcatttc cgtctactcg atcttttgca atcaaatcct ccattacagc
    11521 aattgattta gccggttcgg acaaatcctc acgataaagt ttgtttgctt gtacgatttc
    11581 ttgaagtaat tcatcaggaa tcctttgcga taatctaaaa gaagcctgag gatcatcttt
    11641 aacagaggat gtatttagcc attgtctcaa aatatcgacg acaacatcgc tttttagttc
    11701 attcaattct aacggttgta gccgtctccc taaggcatca tctcttttga tatagttttc
    11761 atattctttt cttgtagtag cggtaatcat ttgaagtgat tcatttgcta acggttcttt
    11821 tagcgaatca cccccaattt tattgccact cccaaaagag ctaacaactt tatgaaactc
    11881 gtcaatgaag aggacaaatt cattatcttt gtcctcagct tttaaaattc gctcatattc
    11941 tttcaatctt ggaattaatg tttctaaacg tgtttggagg acatcatctc ccccaacacg
    12001 caattgtccg attgataatt tatatacttg tactttcttt ccatcttgtc gctgtctttc
    12061 agcccattca cttgcaagtg ctgttttacc tgttccggct tcacctaaca agatagcttg
    12121 cggtgtttcc ggtctattca agatcagtga caactcatgg agttcgtcat cacgtcccac
    12181 taacttatgt tttggtggtt tcattggtgt gagagcatga ttaaattcgg tttgaatatt
    12241 cttaaaaaac tcggtactat tttccatctg tttgtgttca cttcctctaa aataagaata
    12301 atttacttct agtcagtcaa agttaggtac ttaaatgtcg tcttcatgtc tccaaaagaa
    12361 tctttgttaa agtcagcatt tttgtattga tcaatcaatt tttgtgtatc attgattgct
    12421 ttaatttcgg tctccattcg actgtctagt tgacgaatac tttcttgcga atctttatcg
    12481 tcaggatttt gttgtaaacg ttccagatac tcagcttttg tggcttcaat tttcttgatg
    12541 ttagtatttg aagcatttaa ctgatcttct agcttattta caacattatt cttacttgta
    12601 actgctacaa cttttgaata atcaatatcg ccatctttgg taagaaagct tccttgatag
    12661 acattagttg aatctgaata tggatttatt ctgaaattga tattatcagg agtattaaca
    12721 ggttttgctt ttttcccaaa agaaattact ccttcattat taacatcatt catagaatat
    12781 tgagaaagtg cttttgtaac tgaatctgct tcattcacat tgactttggt atcatcgtca
    12841 gctgtatcat caccagaaat tagtgatact tggtttgcaa taaaaacttg ataagctctt
    12901 tcctctaatt taccttttag gaataagaaa gcatccccat cagtacttaa catcccatag
    12961 ctcatttcaa gcttcttagg acgatctttt tcttttgttg ccatatataa gttatagttt
    13021 tttccttgcg tagataacaa ctttctagcg ttttgggagt aaccaagttt tactactgtt
    13081 acatctctat tttgatctgt ccacacatct gaaatagtga tttctgctcc tgatcgagca
    13141 aactccaatg aagaccctat aggtgttgta ttgttcacga gataataatt atagtttcct
    13201 aattgataaa tgtagctacc caagcctgtt aataaaaaaa gcactcctag aaaagttgca
    13261 agcataatgc gtaatccgtg acgtgttctc ttatccttat caccaagcaa ccctccaata
    13321 atactgtatt gatctttggt agatgttgaa ttgacgtttt tttccatcag tttgtctgcc
    13381 ccctttcata aaagagcaaa caatcagacg ttttttcggt aattctaggt tcgggatttt
    13441 gaatcatttc ggtatattct tccccattaa tatttaacac aaaaattatc ttcctttctt
    13501 cgttcctttc ttttgctctt tattttccaa ataatcaatg atttttgcta ttgtaccaag
    13561 atagtaattc ccctcagctt tgttttttcg gattttgcta accattggag taggtacaat
    13621 ctcttcatct ctcaattcac tgaaagattt tttacctaga tattttccaa taacagattt
    13681 taaaaaacgt tcaaaatctt tctcgtaagt tgttttcttg ccttttagtt catggttcat
    13741 attgtcaacg acttttgcgg tttcaataat tgttttagtt ctcagcttaa taatttcatc
    13801 tggaattttc aatcctcgta atttcatcgt tgtactaact ggtaacccat gctttactgc
    13861 atcagcaata ctaaaacttt ttagatcatc tagtaagctc tccatatagt taacaaattc
    13921 atgccaatta atagcattca ttgtctcacc ccttcatttt tttaaaatga ggttcgggcg
    13981 taacacattt atgttattat aatatcataa taacataaat aaatcaatca gcaaatttag
    14041 atatccctta aagtatcagc aattattcaa caagatattt attttagcta tttcagtcat
    14101 cataaaagac taattagcaa taaaataact aatattatcc atttatcaga cgaaaagaaa
    14161 aaacttatct aattactcta tattaacttt taacaaatag ttgacttgtc caaaaatgtt
    14221 accttcaatc tcacaaagat attaagatgt ttcctaccaa aactgatatc accggacttt
    14281 ttattctgtg ttgtccaaaa gtgttacctt tagtcgatca acaaattaaa aaaaattgtt
    14341 tttttcttga cttgtccaaa agtgttaccc atagttgtta aaatttgtat agattagcca
    14401 ttctttcgaa tattatttag actgaaactt gcttacaaaa aaacttcttg catttattgt
    14461 ccaaaagtgt tacccatact tttttaaaga agcaggttgt attaaaatta caaccttctt
    14521 cttctcaatc ttcttctaac caattatgca ttgaaatggt tggcaagttt gattctggct
    14581 cactaaaagt gaatctgagc cgatcaactc ttcttccttt ctttgcatag attttttcat
    14641 aatcaaaagt ttcaaatacc tgtattccgt tttcatcagg agctaaaaat tcttctttcg
    14701 cctgctctag tattcttttg tcaatatttg tcattctata acttgaaggt atacttaatg
    14761 ctcttctaaa atcttcaact ttgactaccc aataaccatt tcgccactct ttatttctgt
    14821 attgcatgag atgacgatac aattcttttg tgtagctact tcttagtttt gtaaaattat
    14881 caagttcaaa acgagtaaag tttttgccaa ttgagtttaa gataaattca aattcctcat
    14941 ttgccttaat tgtaactgtt tccttctgtt tatctatccg gaatttttga aaaagccaca
    15001 gctgttcata gacgtctgaa tcttcaaaac ggtaggttaa agtacctagt ttgtcactca
    15061 aagcttttaa cacagaataa aaactgtcct tttctcttct gtcgtatttg accaaataac
    15121 gaaagaggtt gaaatcaaaa gttacttctg ctgttccttg acgtttcatt tttgataaaa
    15181 tagcccaaaa cacatccatt tcaacaggct taaatcctcg caaagctgtt gtattcagac
    15241 cattgttata acgcacaatt gcatttgttt gttctgatac taaatctaca tcactatcaa
    15301 taatcttttc ggtaacttct tgagacattg attactctcc aatcttcttt ttgcgctcct
    15361 ttaatcatgt taatctggta ctaattaaag gaaacaattt tttctgcttg ttacctaaat
    15421 taaatcacaa ctaaaggtaa cagtcaacaa agatttgtta ctaatctaat tttctatttt
    15481 ttcgccttcc aaatcaagaa aaccgaaggt aacgtcttat cctagtgtga tacctcaaat
    15541 gtccactttt gttacctttg ctgtccaaaa gtgttaccct tactgtccac ttttgttacc
    15601 tttactgtcc aaaagtgtta cctttatacc cctttaatac ttactctccc aagagattaa
    15661 gcctccccta acagatatat taacagatat ttaacagata tattaacaga tatttaataa
    15721 aggaggatta ctcctctctt atttcaaaat cttaaaaata aaaaatctta aaaaaaacta
    15781 acactatcta ggagtttatt ttgcttgtgt aactttgaat aattgaaaaa aaggaaaagg
    15841 aggaagcttc agcttcccct tttatttata tttataatat atattttaat ctttaaaact
    15901 ttagcaacct tcaaaaaggc tttatatcaa tcttaaatag attttagggt ggacataaag
    15961 cgatgcgaac atggacaaaa agcgatgtga atgtggacaa aaagcgatgc aaacgtggac
    16021 aaaaagcgat gtggtattcc gaatatatcc aaaaaaagaa aaagtatgtg aatttatttc
    16081 taaaaactag aaaaatattt gttttttaat tttggtaatt tttataattt cgtatttttt
    16141 tgaaaaggat ttttatattg aaaatgttct aaaatagcga tttctgctgt cttatcaatg
    16201 aaaattgatt aaaaaaataa aatgtgtttt acagagattg agttatgtta taaatttacg
    16261 atacatttct tattgtatcg tatcgaaaac aggtctatac ttattcaatg gaatcgtacc
    16321 agttccaaat ttttaagctc gtaccaagct tagaaagaag aggcaatcgt atgaaaataa
    16381 cagaaaagaa tgtaaacccg aaatttgaac ctaccgaaag caatctaaaa aagtttgatt
    16441 taactgttac tttatcgaat caacttgtag atagcattgt tgaaatggat gctatgccac
    16501 aaaaaattta tctttatgct ataggacatc ttgaccctaa aaatccgcct tttaataata
    16561 ctgttaaagt atctaaaaag gctttatttg cgttgatgtc ttctagttca tcttcttcaa
    16621 aacattcaag attaaaacaa gttattgaaa aattgcatca gcaatctgtc attaaaattc
    16681 aaagaactaa acctaacggt aagactgaat acaaagtcat ctcaccgcta gaaattactg
    16741 aattcaatga tttttctgat gcagtatcta ttaaatttag tagttcaatt atgcctttat
    16801 taacgaactt agaagatcat tttacgcaat atacatttga tcaagtagtt aacttgacaa
    16861 gcaagtatgc gatcagtttt tttcaattat tcactaaaga ttttaatctg tatgaagcaa
    16921 atagagataa cttaacatgg agtacaaaat cacttgatag attaaaaaat cctgttttct
    16981 ccattgcaga tttacgaaag aaatttagta ttgagaaaaa atataaagct tttcgagact
    17041 ttgaaagacg tgtaattaaa gaaccgattg cccaactgaa taaatacact gattttaaaa
    17101 ttgactatga gcttatcaag aagggtcata cttatacaaa cataaagttc ttgcttacac
    17161 gtaccatgtc agttccggta ccttataagc aagaacaaag agaccctgct tatttaaaag
    17221 gcgcagaaga taaaacagag aaaatgaatc aatcgtactt gaaagctatg aatagcaaat
    17281 acactaaatt actaatcaaa aactttttga tcagttctgc cgacttatgc gatcttaaac
    17341 ttatgagccg acttcagaat aaagtttatc cgctttatga tcgtttatcc aaagatagag
    17401 gatttgaatc agttgtcaat cacctatctt acgttgctac tcataaggag gattacacaa
    17461 taaaaaatac tgttaaatat ctcgaaaaat caattacgag ttatttgcct tatgtgaacc
    17521 tttatgatta acaactgaaa aaatgcgtga aggaaggaaa aacttttgaa aaaagatgaa
    17581 ctgacaaagt acaatgagga gttcttagca acaattgaca tgaaaatgga tttaaagtcg
    17641 tatgaacttt atcaattgct gttcagttat atctcaccca caaagctaaa gaaaacaggc
    17701 gtagtagatt tacctgttaa agcgattatt aattacatgg atgttgatca aaatcttgaa
    17761 acggaactaa aaaccatagt taacactttg caaagacaag cagtttatga aatttcgaat
    17821 ctagacaaaa aatataagac gtatactact gtatctgcta ttgatcggat tcattgggat
    17881 ttagaagagc atagtgtatc tttcagtttt tcagaagatg taattccctt aattgtctca
    17941 atcaaaaaga agtatccgtt ctttgttttt gaagacttag catcttttca aaaaaaatat
    18001 agcatcgtgt tatacaaata tttggcgatg tattataaaa aatatcttat cgccaaaaat
    18061 aaaggagatt ttgagaaagc tgaaatatat aagaatcccc tgattgaaat agttaaaatt
    18121 cgtgagatta cgaaaacaga aaatgagtat aaaacaatat cgaattttga tagacgtgtt
    18181 ttaagggaat cagttgagga aattaatgaa aaatcaatgc tgaatattga ttttgctaaa
    18241 gttagaaaag gcagaaatta caattttgct gtccagttta atatttctag tgagtttgat
    18301 gaaaaaactt atagagaaaa aaaattaggt taatgcaaaa tatatcttac tcgtttgaag
    18361 atgcttcaga cgtatgctaa gatatatagt gccttgggag caaggtatta atctccttta
    18421 gaggttaatt agcttgtgat cgcctatcaa tttttttggt aggcgattct tttttttgaa
    18481 acaaaaaagc aaaaattatt ttttaattag agaggtgcaa tgcgatgaaa tacttttttt
    18541 gtgcagtatt cgaatggaaa ggaaatgaat atgcagttaa attcccagat tttccagact
    18601 tatatacaca tggtgaaact ttagaagatg cttttgagat ggcgcaagaa gtattggaag
    18661 gatacttggt gcttttagag ttgcaagaaa aagaaattcc atcgcctacg cctgttcaag
    18721 agttaaatgc aagaatcaag cgatctgaga atgttaattt atttgtcgta aaagctaata
    18781 cgaaagttgc taaagctcga aacaagcaaa attatgatcg aaaatcagtg actgtggaac
    18841 actatttaaa tgttttagcg gctgaagaga atattaatct gtcgaaagct ttgaatgatt
    18901 tgttgagaga aaagttgatt tgatgtctct cagatgatca tattaagcaa aaacagcttg
    18961 ttttaggacg tatg
//
LOCUS       DAPBBR010000047        18705 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPBBR010000047 DAPBBR010000000
VERSION     DAPBBR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.049"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(24..722)
                     /locus_tag="RD488_001982"
     CDS             complement(24..722)
                     /locus_tag="RD488_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDT7658049.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="RD488_001983"
     CDS             complement(715..2067)
                     /locus_tag="RD488_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HDT7658050.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="RD488_001984"
     CDS             complement(2290..3690)
                     /locus_tag="RD488_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDT7658051.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="RD488_001985"
     CDS             3851..4588
                     /locus_tag="RD488_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDT7658052.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="RD488_001986"
     CDS             4713..5192
                     /locus_tag="RD488_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HDT7658053.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="RD488_001987"
     CDS             5189..5956
                     /locus_tag="RD488_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658054.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="RD488_001988"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="RD488_001988"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7658055.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="RD488_001989"
     CDS             complement(6859..7461)
                     /locus_tag="RD488_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7658056.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="RD488_001990"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="RD488_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="RD488_001991"
     CDS             8142..8726
                     /locus_tag="RD488_001991"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDT7658057.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="RD488_001992"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="RD488_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDT7658058.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="RD488_001993"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="RD488_001993"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDT7658059.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="RD488_001994"
     CDS             10627..10806
                     /locus_tag="RD488_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658060.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="RD488_001995"
     CDS             10828..11853
                     /locus_tag="RD488_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDT7658061.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /locus_tag="RD488_001996"
     CDS             12028..13272
                     /locus_tag="RD488_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDT7658062.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="RD488_001997"
     CDS             13425..14372
                     /locus_tag="RD488_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7658063.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="RD488_001998"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="RD488_001998"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDT7658064.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="RD488_001999"
     CDS             complement(15274..15516)
                     /locus_tag="RD488_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658065.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="RD488_002000"
     tRNA            15637..15709
                     /locus_tag="RD488_002000"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
     gene            complement(15828..16466)
                     /locus_tag="RD488_002001"
     CDS             complement(15828..16466)
                     /locus_tag="RD488_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7658066.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16589..17221)
                     /locus_tag="RD488_002002"
     CDS             complement(16589..17221)
                     /locus_tag="RD488_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7658067.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17572..17871
                     /locus_tag="RD488_002003"
     CDS             17572..17871
                     /locus_tag="RD488_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7658068.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18366..>18705
                     /locus_tag="RD488_002004"
     CDS             18366..>18705
                     /locus_tag="RD488_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDT7658069.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQV"
BASE COUNT         6449 a         3221 c         3682 g         5353 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat
    15781 aaagtatgct ttcttagcaa tagagcatgt attatttcta taaaaattta ggagaataaa
    15841 acgactagca atatagctgt gaaatcaaat atcacatgaa ctgcccaact tgtaatgatc
    15901 gagttgcttt taatggcagc ttggttgaat aacaatcttg ccaccccttg tatcaaaagg
    15961 atgtgtgcta cagtgtgtaa aatatttcca ttatcataag tactgtaatg gataaatcca
    16021 aagatgattg ctgacaagaa actagcgaca ggaatgctga acttactaga aaaaatagcg
    16081 agaaaataca ctgagaacaa ttcttctcca agtatcatga taggcaaaat aataaataat
    16141 aacgggctga aagcctcatt tattggattg cctgttaaac cccatttcaa aatttgttgc
    16201 aaaaataccg agactgcggc actgattact acattgataa aaaaatattt ggctatattt
    16261 ttgacaggag cgacaggttt cgagaacatt tttttcgtat cttttttacc aaaaacaagt
    16321 gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc taataatgga tggcgcaaat
    16381 agcaacccta acaaaccgag tacaacgaca atagtgccca atatcccttt tttaagttct
    16441 attttttttc ctaaaatgtt attcatgata ataactccta ctattcagtt tttgaagata
    16501 gagtcagtat acatgaagag ttaaaatagg caatgttttt ttatggatat ttgtattgct
    16561 aaaaatttat cttatatatt cattttgatt atactacttt tatttgtaaa aattttctag
    16621 caaaaccaag tgcttgcaac tgattaagcg tacaattttt tagatgttcc gagcgtactt
    16681 caatcatttc aaaggagttg ctacttaaat cgatattttt taaatcagta tcaaaaaagc
    16741 tagcattttc taaatcatta gtagaaaaca ttattttagt gagggaacag tctacaaaat
    16801 ctgcgcttga taagacagag tgctcaaagg tactttcttt tatgtttgaa ccagataaat
    16861 ttacatagtc cattttacaa ttctcgaata acgtgttccc aatataactt tccatcaatt
    16921 tagtacctgt taatttacaa ttgacaaatt tcacgcgatg caacatgctt tttgtcaata
    16981 tacagcctga aaaatcacag ttttcgaata tacagtcggt aatctccatt ctttgaaaat
    17041 cattggaagc aaaaaatgca tacttgaaaa tagatttgta aataattgga tggcagatta
    17101 tttggttttc gatgacctct ttttgtgaaa ggatattata cagttcaaaa tcttcgtttt
    17161 catagatatg aaaaaaggat cctttattca agcttgcttc attaacttta ggaaaaatca
    17221 tatttaatta cctccatttt cataaagtca tattaacaaa agctaaacca acttacatta
    17281 gcagaaaatg agataggttt tcgccttttt cgataacgat agtgtcgcta tctcttgaaa
    17341 cgttcttaga attgccctga gagacacaaa ttaggcgtaa ttctaataaa aatcttagaa
    17401 taaaaatttt tactgattta atttagaatg tttttaaaat aaaaatcgtt gccataacag
    17461 tgtattgaaa ggttttaaca atccagtaat gatttaaaaa aatctagatg tagcgtatac
    17521 tttgtttata gaatgtagtg ggaagaaata tatttttggg aggaaatcgt gatgtctaaa
    17581 agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc tcgttttaaa tccagagatc
    17641 aaagaaaagg aacgtatact tttgatagac gcaaagacag gcttagaaaa aggtcagtat
    17701 tatcctaaag tcataaataa tttggaacgt agtttacgtc cgttagcaat caggggagaa
    17761 ttgtctaaac cagtatcacc gttttatatg gagatatcaa caataggaaa atttgaaaaa
    17821 gaattaggtc gaggaatggc ttcggcaccg attacttttg ggcatttata aaaacgagtt
    17881 attcatctca atgaattaaa aagtatagtc aatctcataa tgcaggctag gttcatttat
    17941 ttgaacagag tctgtatttt tttattctaa ataaagaaac agatgtttct ttatattgta
    18001 ttttatcctt taattaacac aaaaacagct agtataaact aataatgtta attaaaagtg
    18061 tattttatga aactatcgtt atttattaat gttgcatttt tgtaagttaa aaattggaaa
    18121 tatagattga aaaaatgaaa gcaataagta aaataaaatg aatatatgcg aaaaaataat
    18181 ttacattagg aaaaaccttg taaaaacagt tttttggcat atttattttt tataaatatt
    18241 tgtaaaataa ctatcaattt tttagttaaa agattggaaa tgagtggggg aggaattgaa
    18301 gaaaggattt ttgagagatg atatagtagg ttttattttt agttaaaata ggggagatag
    18361 aaaaaatgaa aaagtgtaga aatattattt tatcaatgtt atttattatt actaatataa
    18421 catcactgat tcctgttcat gtctatgcgg atgcaggcag agatatcagc agtaatgtca
    18481 cttcgttgac cgtggaccca acgaatatta cagatggagg aaacataaaa gtaaaattct
    18541 cgtttgacga aaaaaaacaa aatatccaac caggtgatta tctttggatc aattggccaa
    18601 gtgaaggaaa tattcgcggt gaaggattcc aaaaagaaat cccattaatg attgaaaata
    18661 aaaatgttgg aactttaacg gtcagaaaag attctgcgca ggttg
//
LOCUS       DAPBBR010000048        17965 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPBBR010000048 DAPBBR010000000
VERSION     DAPBBR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.050"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="RD488_002005"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="RD488_002005"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDT7658070.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="RD488_002006"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="RD488_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDT7658071.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     IGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="RD488_002007"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="RD488_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDT7658072.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="RD488_002008"
     CDS             complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="RD488_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDT7658073.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="RD488_002009"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="RD488_002009"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDT7658074.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="RD488_002010"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="RD488_002010"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDT7658075.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="RD488_002011"
     CDS             complement(8054..8524)
                     /locus_tag="RD488_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDT7658076.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="RD488_002012"
     CDS             complement(8570..8995)
                     /locus_tag="RD488_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDT7658077.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="RD488_002013"
     CDS             complement(9062..9331)
                     /locus_tag="RD488_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDT7658078.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="RD488_002014"
     CDS             complement(9342..10937)
                     /locus_tag="RD488_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7658079.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="RD488_002015"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="RD488_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDT7658080.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /locus_tag="RD488_002016"
     CDS             complement(14490..15050)
                     /locus_tag="RD488_002016"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDT7658081.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="RD488_002017"
     CDS             15403..16377
                     /locus_tag="RD488_002017"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7658082.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="RD488_002018"
     CDS             16547..17947
                     /locus_tag="RD488_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDT7658083.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
BASE COUNT         4883 a         3970 c         3240 g         5872 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagcct atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttatac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaa
//
LOCUS       DAPBBR010000049        17007 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPBBR010000049 DAPBBR010000000
VERSION     DAPBBR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.052"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..126)
                     /locus_tag="RD488_002019"
     CDS             complement(<1..126)
                     /locus_tag="RD488_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HDT7658084.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="RD488_002020"
     CDS             complement(230..541)
                     /locus_tag="RD488_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7658085.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="RD488_002021"
     CDS             complement(543..740)
                     /locus_tag="RD488_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HDT7658086.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="RD488_002022"
     CDS             complement(1134..2861)
                     /locus_tag="RD488_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HDT7658087.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="RD488_002023"
     CDS             complement(2854..4047)
                     /locus_tag="RD488_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7658088.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="RD488_002024"
     CDS             complement(4234..4878)
                     /locus_tag="RD488_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7658089.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="RD488_002025"
     CDS             complement(4972..5106)
                     /locus_tag="RD488_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDT7658090.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="RD488_002026"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="RD488_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDT7658091.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="RD488_002027"
     CDS             complement(7237..7710)
                     /locus_tag="RD488_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDT7658092.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="RD488_002028"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="RD488_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDT7658093.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="RD488_002029"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="RD488_002029"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDT7658094.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="RD488_002030"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="RD488_002030"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDT7658095.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="RD488_002031"
     CDS             complement(11757..12896)
                     /locus_tag="RD488_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7658096.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="RD488_002032"
     CDS             complement(13205..13918)
                     /locus_tag="RD488_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDT7658097.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="RD488_002033"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="RD488_002033"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDT7658098.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="RD488_002034"
     CDS             15107..16639
                     /locus_tag="RD488_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7658099.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="RD488_002035"
     CDS             complement(16830..>17007)
                     /locus_tag="RD488_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7658100.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DAPBBR010000050        16884 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPBBR010000050 DAPBBR010000000
VERSION     DAPBBR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.053"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(258..1763)
                     /locus_tag="RD488_002036"
     CDS             complement(258..1763)
                     /locus_tag="RD488_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7658101.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1760..2446)
                     /locus_tag="RD488_002037"
     CDS             complement(1760..2446)
                     /locus_tag="RD488_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7658102.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="RD488_002038"
     CDS             complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="RD488_002038"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDT7658103.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="RD488_002039"
     CDS             complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="RD488_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7658104.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4467..5036)
                     /locus_tag="RD488_002040"
     CDS             complement(4467..5036)
                     /locus_tag="RD488_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDT7658105.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5222..6124
                     /locus_tag="RD488_002041"
     CDS             5222..6124
                     /locus_tag="RD488_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7658106.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6159..7943)
                     /gene="pyk"
                     /locus_tag="RD488_002042"
     CDS             complement(6159..7943)
                     /gene="pyk"
                     /locus_tag="RD488_002042"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDT7658107.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(8017..8979)
                     /gene="pfkA"
                     /locus_tag="RD488_002043"
     CDS             complement(8017..8979)
                     /gene="pfkA"
                     /locus_tag="RD488_002043"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDT7658108.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9147..12461)
                     /gene="dnaE"
                     /locus_tag="RD488_002044"
     CDS             complement(9147..12461)
                     /gene="dnaE"
                     /locus_tag="RD488_002044"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDT7658109.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            12692..12877
                     /locus_tag="RD488_002045"
     CDS             12692..12877
                     /locus_tag="RD488_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDT7658110.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(12939..14135)
                     /locus_tag="RD488_002046"
     CDS             complement(12939..14135)
                     /locus_tag="RD488_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7658111.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14305..15741)
                     /locus_tag="RD488_002047"
     CDS             complement(14305..15741)
                     /locus_tag="RD488_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7658112.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            16034..16843
                     /locus_tag="RD488_002048"
     CDS             16034..16843
                     /locus_tag="RD488_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7658113.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         4954 a         3539 c         2950 g         5441 t
ORIGIN      
        1 aaataataat atagcaatct ctttataaaa ttgcaataga aaattcccta tttttattta
       61 ttatttttaa acacgaatat tacagcattt tattgttttt tcgttcatct aaaagatact
      121 tacatttaat taacggatgt tattctattt aattgttcgc tagttttttt ataatgacat
      181 ccctgaattt ctcacttgct tgtattttgt accttattct ttgttggata tataaaaaaa
      241 caagtaaagc acatgcttta cttgtcttct gcctttgcga taggaataaa gattctaaaa
      301 attgtccctt gccctactac actttctgct aagatacgtc ctttatagtt ttcaaccagt
      361 tgtttagcga tagacaaccc cagaccattt ccacccttcg ttctagctct tgctttatcc
      421 actcgataaa aacgattgaa gatcttatta aggtcttctt tgggtattcc ttcgccaaag
      481 tcctgaatcg cgatctcaaa ttcattcaga gtggaagaaa tagagatatg gacttctttt
      541 cgtgtagttg aatactttac tgcgttatcc aatatgataa tgattaattg ttcaaagtga
      601 ttacgataaa tttgcagggt cacttctttt gtcaaatcat catctaaagt gatcacatag
      661 tctggatata atatcttgaa attattataa acttgatagg tgacttcttt tcctttagtt
      721 gtttcattcg cataatgaac atctacttgt tctgctcttg ataagtctag catctcttga
      781 actaagcttt tcatacggct gatttcttgc atgctggcgc ttaatgattc ttctaatatc
      841 tcaggatcat ctttccccca acgatttagc agactaagat gcccttcaat aattgcaaca
      901 ggtgtcctta actcatgaga tacgtcttcc acgaattgct cttgttgttc aatatacaaa
      961 cgcatacggt caagcatctc attgaatatt tcagctaaat ctgccaattc atcatttgtg
     1021 tcgatttcag gcatgtggat atctgattgc ggatctttac gtatagtatc cattgtatct
     1081 ctgagtacct tgagtggttt taagaaataa gaagataaaa agaaacctaa aatactactt
     1141 aagatcaaag aaacaacttc taaaacaata agagtcaata atagcttatt tcgaatatca
     1201 tagaaagaag ataattcata gaagctttgc gcatagccga tcttttctct tgtaccttta
     1261 gaatatatag gctggataga taaaaagcca gtttttcctt ctagtgtaac gatcgttgga
     1321 actttacgtg tagtctgaat caggtttcga ctgttttcat gggttttaaa aatcaagttc
     1381 tcgtccaaat cataaacata aagatccatt gatggctgcc ctagctcagc tataaaggaa
     1441 tcgatcttca ttaagtttcc ttcgaccagt gaagtatgat ctacgacctc atctccgtca
     1501 tttgtcgctt tcgtcagatt acgatacgta tttactaatg tcagttcttc atccgagtta
     1561 gccaaacgag aagctacttc tgaaatcgta cgctctacat tgtttctttc ttttgccaca
     1621 atcagattga tagatgattt ataggtaatg acagcgaaaa ttgtaaacac aacgaatatg
     1681 aagaaagaac tcgcaaaggc ccacttgatt gtcaaggagg gccctttcag ttctcttttt
     1741 tccgattttt tcggctttat cacgagcgca tcacataacc tgttccgcgt acagtttgga
     1801 tatagctttc ctccccggga acgtcaattt tgttgcgaag ataacgaata tatacgtcca
     1861 ctacgtttgt ttcaacttct gtttcgtatc cccacacttt atttagtaaa acgtcacgtg
     1921 ctaataccac gttcacgttt tccattaaag taagcagcaa ctcgtattct ctttttgtta
     1981 gttcaattac ttcatttccg cgacgtacga cacggttttc tttttcgata gtcaaatcgc
     2041 gataagtaat agtagtttgt ttagccacat ttttatcgcc ttcaatatcg attcgacgca
     2101 acaatgcacg aagacgtgct aataattctt cgatagcaaa tggtttgacg atgtagtcat
     2161 ctgctccgtg gtcaagtcca gatacacgat cgatcacaga atctcttgca gtcatcataa
     2221 tgattggtgt atttttgact tggcgtacac gtctgcagac ttctaaaccg ttcaattctg
     2281 ggagcatcag atccaacaat atggcatccc actcattatt taatgccgca tctaaaccag
     2341 ttcggccgtt gtagtggact tctgcgttat acccttcatg cttcaactct agctcgacaa
     2401 atcgtgccaa gttcttttca tcttcaatga ttagaatatt gctcatttat tattttatcc
     2461 tttctattct actggctttt taaaaactct atcattatac cgataatatg cttaaaaatc
     2521 tatagtcatt ttattatgga tagcaatttt aaaaaagagc tgaagtctac tcataacaat
     2581 cgacttcagc tctttcgtcc tctttttatt ttctcatttc ctaacagccg aaagactatt
     2641 attcttcatg gtaccatgag taatggaaga ttccttcttt gtcgacacgc tcataggtat
     2701 gtgcgccaaa gtaatcgcgt tgggcttgga ttatatttgc aggcagacgt tctgctctgt
     2761 atgaatcgaa gtaagcgatg gctgatgaga aagtcggtac aggtacgcca gcttggacag
     2821 ccaaggcaac gacgtctctg actgattgct gatatttttt cgtgatttca acgaagtaat
     2881 catctagcaa taaattttcg atctcaggat ttttgtcata ggcatccgta attttttgca
     2941 agaatcgagc tcggatgata catccagcgc gccagatttt tgcgatttca ccaaatggca
     3001 agtcccaatc aaattctttt gaagcgacac gtaattgagc aaatccttgg gcataactca
     3061 tgattttact gaaatacaac gcttctcgga ttttttcgac caattctttt ttgtctcccg
     3121 tgaactcaaa atcgttcgta cgagacaaaa tcttgcttgc ttgtacgcgt tcttctttat
     3181 aagcagaaat atagcgggca aatacagatt cagtgatcaa tggaagtggc acacctaagt
     3241 caagcgcgct ttggcttgtc catttacctg ttcctttatt cccagctgca tcaaggatca
     3301 catctactac tggtttacct gttccttcat cgtctttacg tgtcagaatg tcagcagtga
     3361 tttctatcaa atagctgtct aattcgcctt gattccattc tttaaagata tcagccattt
     3421 cttctactga aaggtttaaa atattcttca ttaagtcata agattcagca atcagttgca
     3481 tatctccata ctcaataccg ttgtgtacca ttttcacata atgtccggct ccatttgggc
     3541 caatatatgt gacacatggt gctccgtctt ctgcttttgc agaaatttgc tctaagattg
     3601 gtgcaactag cgcataggct tctttttgtc caccaggcat gattgaaggt ccttttaaag
     3661 ctccttcttc accaccggaa acgcctgtac cgataaagtt gatgccagag ttggctaact
     3721 cttcattacg acgcatcgta tctttaaaga atgtatttcc tccgtcaatc aaaatatcgc
     3781 ctttatcaag gtgaggaagt aactcttgga ttgttgcatc tgttgccggt cctgctttga
     3841 ccattagcaa gatccgacgt ggtttctcga tagattctac aaattcttcg attgtatatg
     3901 ttgctttgaa atttttatct gggtgttctt ctactacagc ggttgtttta gcccctgtac
     3961 gattgaataa agccactgaa tagccgcggc tttctatgtt caaggctaga tttttaccca
     4021 taacggccat accgacaacg ccgatttgtt gttttgacat atgaactcct cctacatacg
     4081 ggatttctcc ctaatctctt acattatagc ttaacacggc tacattgcaa actaaagaac
     4141 aacatatttt ttatttaccg actacaaaaa aataaacctc aaggctccat ggttagcctt
     4201 gaggttttac attttctaat taaaatgtat taagcttctt ttgacattac gtccttacca
     4261 tcatagtaac cacaatttgc acatacgtga tggctttttt tcatttcacc acagtttgga
     4321 cattcgttta accctttgat tgtcaatttg tagtgtgtac gacgttttgc ttttttagct
     4381 tttgatgttc ttctagctgg tactgccatt ttgctacacc tccttgtaaa gtcttgtatc
     4441 taaattagac acaatatatt ccaatcttac ttgttatcgt cgtcttttga tttagaatca
     4501 aaaagttcag atagttttgc aagacgagga tcaattttat tctcggcttc ttccattttt
     4561 ctgcgctggt attcttcttc ggaaacaact tcccaatcat tgccttttgg aagttctgtt
     4621 gctgcttcct cttcttttgt caatacccgc attggaatcg ccaataagat gttgtcttca
     4681 atcgactctg ctaaattcaa taatggacct tcaattagca aaatctcatc tgcagacatt
     4741 tgttcatctc tactttggaa ttgttcttct gtcatgaata cttcgtctac agaaaaatcc
     4801 atgggcagtt caacaggttc tagtgaacgt gttgaaggaa ctgtcaaagt cgtctgcaca
     4861 gtgtaatgaa cgatatagcc tttcttatca actgagacca aaccttcgac ttccactggc
     4921 gcaacatcaa gtattaaatt gtctcgcttc atgagagcgg ctttcaagtc gagcgtctca
     4981 tgaaaagtta acggtgtctc ctggtatttt ctcaattcca ataaagacca tttcattttt
     5041 catcactcct aagcaacaaa agcaattata cagggcaaaa agcatgttgt caatgaaatt
     5101 ttcttgacac cttgcagttc ataaaaaaac agaaaaatct ttattagaaa gcctctgttt
     5161 gctatcatcc tcagaatcat ttacaataat cattattcca ttaaaggagc ggatgatctt
     5221 catgaacacg aaagatatcg aatactatgt ccaaatcgtc aaacaaaaaa attttacgaa
     5281 agtggctaat tatttccgtg tgagccaacc tactattaca tatgcattac aacgtcttga
     5341 aaaagagttt gacaccgtac ttattacaag agatcgatcg catcacgaat tgatcgtcac
     5401 gccttctgga aagcagctgt ttctccatgc acaaaccatt ctccaagaga tttctactgc
     5461 aagagctgaa atcactcagt tgcaaaagaa aaagcttcgt tttggcatgc ctcctattat
     5521 cggcaatgaa tactttccta aactgtcaag ttactttatc aagcatgaat tgatgaatca
     5581 aattgagatt accgatggag gctctcggga cttatacggg atgatccgac aagggaggat
     5641 cgatttagct gtattaggct caacacagcc aatcgtggat caatatttag aaacagagtt
     5701 acttttggac aaacgtttca tgatcgtcgt gccacctaca catcctcttt ccaagcagga
     5761 tactgtctct ttcaaagata tagcagatga acagtttgta ctattgaacg aacattatgt
     5821 ccaccccgca gcattcacta agctttctaa acaaacacat actcatccaa aagttgttta
     5881 tcaaagcaat gacttgacga ttttaaagag tatggtccga gaaaatgtgg gtatcggttt
     5941 tttggcagag attgctgtcc atcctgaaga tcatttagtt tgcctccctc tttcagatga
     6001 agttcagcct cgcttcttga tttcattggc aaaacgaaca cagcagatcg tcacgcctct
     6061 tcaagaacaa gtagtccaag ttatccatga attcgttaca gcacaaaaaa acagctcttc
     6121 gtaaaagaag agctgttttt attttttatt aagctaaatt agatagctgt tgtttcgcca
     6181 cggtaaacga tgccgcgacg tgaatcaacg gtaatcaatt caccttctgt aattgttgtt
     6241 gttgcgcctt tagcaccaac gattacagga atatcttgtg caattcctac aactgcagcg
     6301 tgagaagtca atccgccttc ttcaacgata acagcagctg ctttttcgat tgcaggcata
     6361 tattctttgt cagttgatgg tacaactaga accattccgt cttttgcttt ttttacagct
     6421 tcttcagcag atgaagcaat aactgcattt gcaacgacag atttttgtcc aacgccttga
     6481 gcttctaata atttagaacc aatcatttga attttcatca cgttagttgt tccgcgttca
     6541 ccaactggta caccagcagt gatcaagatt aaatcgcctt ctgatgcgaa acctaattca
     6601 acagcttttt tagctgctag ttcaaacatt tcatcagttg ttgatggttt ttcagcaact
     6661 gttgggtaaa cgccccagtt taacatcaaa ccacgttttg tgcgttcgtc aaaagtaaca
     6721 gccaagatat ctgcatctgg acgatatttt gaaatcattt ttgcagtgta tcctgattca
     6781 gttgcagcaa cgattgtttt cacgcctaga ttttttgcag cacgagctac agataaaccg
     6841 attgtttcag ttacatctgt tttatcgaat tcgttcaatt ggaatgtacc taattctgat
     6901 aatgcatttt cagcttcttg gtcgatacgt gccattgttg aaacagcttc aactgggtag
     6961 tccccgtttg cagattcacc agatagcatt gttgcatctg tgccatcaaa tacagcgtta
     7021 gcaacgtcag aagcttccgc acgtgttgga cgtgggtttt cttgcattga ttctaacatt
     7081 tgtgtagcag tgataactgg gataccagca gcattacatt ttttgataat gcgtttttga
     7141 accattggta ctagttcagc tgggatttca acacccatat ctccgcgggc aatcataaca
     7201 ccgtcagaaa ctttgatgat ttcgtcaatg ttgtcgatac cttcttgaga ttcgatttta
     7261 gggaagattt gaacatgagt catgtctttt tcttctaaga tttcgcggat atctagaacg
     7321 tcttgtgctt tacgtacaaa acttgcagcg ataaagtcga tatcgttgtc taaaccaaaa
     7381 cgaatatcgt cagcatcttt tggagtaata cctggcaaac taatagaaac gcctggtgca
     7441 tttacccctt tacgtgatcc tagcatacct gcatttttaa cttctacgac taattcacgg
     7501 tttgcttcgt ctttttcaat gatttgcata tcgatcaaac catcatcaaa taaaatgtgt
     7561 ccgccaacgt gaacatcgtc aaataatcct gggtaagtaa ccgcgatttt ttcttttgaa
     7621 cctacatgtt caggatccat agagatgcgt gtttgatctc ctacttcaaa tttgatgtat
     7681 cctgcacgac caaaatcagc ttctgttgtg ccttgaacag ttgtacggat ttcagctcct
     7741 tttgtatcta aaagaatacc gacatctttt cctgtctttt taactgcttc acggaccata
     7801 gtcatacgtg ataattgttc ttcatggtca ccatgagaaa aattaaagcg gaagacattt
     7861 gccccagatt caatcaattg agaaataatt tctactgagt tacttgctgg tcctaatgta
     7921 ctaacgattt tggttttttt catttaaaaa actctcccat tcaattttgt ttatttaaag
     7981 ctgtacacag cttaaatagc ttggtttctt tcactcttaa aatgaaagtg aattatttag
     8041 atcatatagt gataagtctg gtttatgttt gttgttttca agtgtatcaa tgatgtcaga
     8101 cgcaacgatt tcgttgtcat ggataccgac acataatcca ccttttcctt cttgaagcaa
     8161 ttcgacagcg taagcaccga atttacttgc caacacgcgg tcgcgtgcgc ttggtgctcc
     8221 accacggaca acgtgtccca agatagatac acgtgtatga tagtcaccaa attctgaaag
     8281 tttctcagcg aattcatttc cgcccattac accttcagcc aagatgatca agcaatgttt
     8341 cttcccgcga tcgcggcctt cttggatttt tttagcaact gaagccatat caaaatcatg
     8401 ttctgggatg atgatttcat ccgctccgcc agccacacct gaccataaag cgatgtctcc
     8461 tgcattgcgt cccattactt cgataacgaa tgtacgaaca tgagaagtcg ctgtgtcacg
     8521 aatacggtca attgattcta gtactgtatt gattgctgta tcaaaaccga ttgtgaaatc
     8581 agtcccagga atatcattat cgattgttcc aggaatacct actgctggga aaccgcgttt
     8641 tgtcaaagcc attgcgccat gataagagcc gtctcctccg ataaccacta gaccttcgat
     8701 tccgaatttt ttcaattgtt cgattccttt taattgacct tcttcagttg caaattctgg
     8761 ataacgtgca gaatacaaga atgtaccacc acgttggatc ttgtcaccta catctgccac
     8821 atcaagacga cgaatatctc cagcaactaa accggcaaaa ccataattga tcccgtatac
     8881 ttccagtcct tcgtaaatac ctttacgaac aacggcacga acagctgcat tcattccagg
     8941 tgcgtctccg ccactggtca aaattccgat gcgtttcata ataaacattc acctcattaa
     9001 aatactttat cctaagtatg acttaggttt acaaccattt ttgcgttaac cacgactaac
     9061 attctaacat tatttttctc acttgtcttg atttacggat aaaaaaatga aaaaaaatga
     9121 aagcaagtag tattttttac cgtaagttat ttgaaaacca cattatcttc gccaagcaga
     9181 taaataagtt gccgctttat actcttgctg tcatccaccc aataagcatc tgacagaact
     9241 acttttcgtt gcgttttttc gtgatacata actactggta tatatcctgg gtgtttctga
     9301 aaaatcactt gtaattgttt cattatctcg ggatcttccc gttcttctgt aatacgcaaa
     9361 tagcaagttt gtgaaggata ctgggcttct aactggttag gatcagcaaa gctttctcca
     9421 attagttgca gttcctgatt atatttgctg atttcgctcc gcccttgaac aaagatcact
     9481 cgatcaacgg caaacaaatt acgatattta cgataaagag ttggaaaaac tgtgacagaa
     9541 atttctccac tactgtcggt tccttcaaca aaggccatca gttctccttt ttttgtccga
     9601 atttctctaa cttccttgat catcactaat aaattgactg gttgattagg gacgatatct
     9661 gtaatcagct gaacttgttt agctaaacga agacgatcaa acccttctgc aggatgacct
     9721 gacaaataaa tacctaagta ctcctcttcc agcttcaagc gttcttctag tgtatagtca
     9781 gcgacttctt cttcttttaa tgccatgatt cccagcaagt caagacttcc accactgtaa
     9841 acgatatttt ggatttttcc ttcgagatca agcatcaatt gtttcctgtt aggagataat
     9901 tcatcaaaaa ctcctactgc tgtcagtgat tgcagtaact ctaatttcag ccaacgctta
     9961 tcgatccgta tgaggaattg atccactgac tggaacgggc cattttgttt tctttcgttt
    10021 aatatatctt ctacaaaatc acgccgaata ccttttatcg ctgtcagtcc gaatctgatt
    10081 tcttccttat tgaccaactc aaaactggaa ttactttgat taatggacgg cgaggaaagt
    10141 ttgagtttat ttttacgtgc ttctgcaata tattctttca attttgatgt gttatgccga
    10201 acagaattca tcaggctggt aaagaaagca cctggatgat gggcttttag atacgccatt
    10261 tggaatccca cgaatgaata agcaaatgca tgtgaccgat tgaatccata gtttgcaaat
    10321 ttttcgatat attcatatac ggtcgctgct gttttttccg aatatccctg ttgtaatgct
    10381 cctgatacaa aatgcgactt ttcttcatct aatacgtctt ttttcttttt actcactgcc
    10441 cgtcgcagaa tatctgactg ccctaatgta aatccagcca tagtcgaggc gatctgcatg
    10501 atttgttcct gatagacgat cactccatat gtgtttttca aaatcgggat cagtgaatca
    10561 tctgggtagc gaatggcttc ttttcctttc ttcctggcaa tgaaggtatc tatattttgc
    10621 atagggcctg gtcgatacaa tgcattgact gcggcaatat cttcgatgtt ttctggatct
    10681 aatcttcgta aaacgttccg gataccagca gattcaaatt gaaatactcc tgaggtttcg
    10741 cctcgttgaa acaagagcag cgtttttgca tcatttagcg ggatctcttt taatcggatc
    10801 tcataccctt ctactcgctt aacagctttc aaagtaaaat caataatcga taagttgcgt
    10861 agtcctaaaa agtccatttt caaaagaccg attgcttcta cctcattcat cgtatactgg
    10921 gtcagaaaag cttcatcaga accgcgttgg agcggaacta gttcaagtag attcttatcg
    10981 ctgataacta cacctgctgc gtgagtcgaa acatgtcttg gcaatccttc taaaatcact
    11041 gcagttttga ataaaagttg gtttttttcg cttgcctgaa ctaattctac taattgatgc
    11101 gaagttttat aagcttgggt caatgtgatt ttcaattgat tgggtattgc ttttgaccag
    11161 cggtttgctt cactttgcga taaaccaaac actctagctg catctctaag aaccattttt
    11221 gctgccattg tgccaaatgt tgcgatttgt gccatatgat attgtccata cttttctcga
    11281 acataattca atacttcttc acgtcgattg tcaggaatat ccaaatcgat atctggcatc
    11341 gtaaagcgtt cggggtttaa aaagcgttcg aacagcaaat catattctaa tggatccaca
    11401 tctgtgattt ctaacacata ggctactaat gaacccgcag cagaaccacg acctgcaccg
    11461 gtaacgattt tgtttctatg agcaaaagcc attacatccc atacgatcaa gaaataatca
    11521 tcgaatccca tttgatggat gacagataac tcgtagtcca aacgttcttg gtattccttt
    11581 gtatagtcag tgattcggcg ttccacttgc gaatagcata actctcttaa atattctcca
    11641 gcttgttttc cattaggaac tggataatgc ggaagtaatt tctgatggaa ctggaattca
    11701 aatgaaatcg attcagctaa acgctgggcg cctattacag cttgggaaag acccgctttt
    11761 tcgaatcgtt tgatcatttc ttgttctgaa agaagataga catttgctgt tagtggtaaa
    11821 gatgcagata aattttctaa aggtatttgg cttccctctt tgatatgttt catcacttca
    11881 agtgcaaaaa gttcttcttg ttgtaaacta gcgatgggat gtaatgcaca aagcgaataa
    11941 ttttctttta tcacatactg ataccattca ggcaattgat caggcgtgtt ttctgtcaag
    12001 ccgatataaa aatttctagt aaaaacattt tcaagtaaaa actgccaatg accgaaaaag
    12061 ttatcctctt tattgaaagc ctcagaaaca gaatgatttg ccggaacaac aaacgctaga
    12121 tggtcggttt ctgtcatttc tgcaagttcc aatttttctt ggatcatttt tcggctggaa
    12181 agtttcatca gctgctgata acctatttca tcttttgcgt acgcaagcaa gccataattt
    12241 ttttcttcat aagtataact aagatgtaat ccaatgattg gctgtactcc ttcttctaca
    12301 caaatacgat agaattcagg tgcaccgtat aagacatctt tatccgttat ggctaatgaa
    12361 gtgtagcctt gtttttttgc ttcttgtaca tattctcgaa tacgtatcgt actttgtaaa
    12421 agagaataag aagtaattgt ataaagttgt gggaaaaaca tcttgcattc cgcctttttt
    12481 ttcgttaaaa ttcactagcg ttaaaaggtt tgatcctttt actttcatta agatagcagg
    12541 cgctgaagtt gattattcca cttcatttgc ttgcttgtaa tctgtaggaa tgagttcttt
    12601 cgcaagaact caaattttat tgagatttgg tctcgtttct ttacattcaa agaaaatctg
    12661 gtaaaattaa gatagaaaag aggtgttctt tatgcgatat atcgttacat tattctgggc
    12721 tgtcgttcta ggtcaagtag tcggttatat tggtgctgca ttaacaagcg gaacatatga
    12781 ttttactttg acaacaatca tttcattcat tgcgggtgtc attatccttt tgattggtgc
    12841 agttgcgcca agaaaagaaa cctctgccca ttcgtaaaaa aacagccaag agcttgagat
    12901 ttctcaagct cttttttatt ttctactcct caccaccatt ataatctgct gcgaagaact
    12961 ttacgaaagt tgaataaaga aagaagaata tttgacagaa caaacaaact tgtcacaata
    13021 aaaacagcac tgtaattata agcatgcgcg actgtcgatc ctagcatggg acctaaaact
    13081 tgtccaaagt tgctaaacat ctgattgtag ctatagattc ggctgactcc ttcttgaggc
    13141 gtaatcttac tgatcagtgt attgacagaa ggcatcaaag cgccagttga aaagcctaaa
    13201 ataaagcgaa gtatacctaa ttggagcggt gtagtgacga atgccatagg taaataacag
    13261 caaaatgata aaatgagtcc tccaattaga actttttgat tcccaatctt atcccctagt
    13321 tttcctagtt tcggtgaaga aaagacagcg gaaacaccag ctatcgaaac aatcaagccg
    13381 ctgacaaaaa ggatattttc tgtacttccg ctcaattcac gaatatataa ggtcaaaata
    13441 gggctgatcg tagtgattcc tatctgtaaa atcaaggtcg taatgaagag accgatcaaa
    13501 atagagagat gatccatttt tgaaaaaatt tctttggtgc ttatcagatc ttttttctcg
    13561 attggatgga aatcttcttt gactaagaaa atggtcaata ccgttgtgat catcaacaaa
    13621 gcccctgtga tcaagaatac attttccata ccaaaccact gagccagtgc accgcccatt
    13681 gaaggtccga tcagatttcc agcaatcgct ccggtagaca atgttcctaa cgcccatccg
    13741 ctcttttctc taggtgcctg tgaagcaatc atcgctgtgg catttggaat atatccagac
    13801 aaaatcccat tccaaaaccg catgatcaaa agccaatacg cgtttggtac aaaagccaaa
    13861 gatcccattg ttaatgtcat ccctgctgct gcacggatca tcatgagttt tcggcctttt
    13921 cgatcagcta gatttcccca gattggtgca accacggcag atgcaaaagc agtcacagag
    13981 attgctagtc ccgaaaacaa ttcgatttga tcttttggtg ttcctagttg ctcaacataa
    14041 actggtatga atggcataac taaactaata cttgcaccag tgaaaaaaca gccaatccac
    14101 gcaatcacta aattttttct ccaattaatc tccatctatc atccctcttt cgtctctttt
    14161 atcataccta ttttcgaata aacaagcaac gatctcgcca gtaaaaagag aaaaatcccg
    14221 caaaggtcat tttatatgta acgttctttt tatgtaaaac aaaaagagat cagaacaaat
    14281 actgttccaa tcccttctct ttagttaaat tgttgctaga atgatgaagt tgataatgaa
    14341 taaaatatca acgatccaca aagcaacaga aacttgattg tattttcctt tgattacttt
    14401 cacaattgta tagaaaataa atcctgctgc aatcccatag gaaatgctat agcacaatcc
    14461 cataaagatc gatgcaaaga aggccggtaa agcttcttcc atatctagcc atttgatgtc
    14521 tgcaaaagaa gccatcatca ttactccaac taaaatcaat gctggcgcag ttgcttgatt
    14581 tggtacaatg gcgatcagtg gagagaataa actacttaat gcgaatagca ctgccactac
    14641 tactgaagtc aaaccagtac gtccaccggc cccgatccca gctgcagatt cgacataagt
    14701 tgttgtattc gatgtaccaa agatagcccc cacagaagta gcgatcgcat cggcaaatag
    14761 tgctttatcc atttttgttt tgaacccacg accatcttcc aacgcgatct cgtcttcttt
    14821 tgagaaaata cctgtgcggc gtcctgtacc gataaatgtt ccgatcgtat cgaaagtatc
    14881 agataaactg aatgcgatga tcgtcatcaa tacttgagga atcttggaag aatcactgaa
    14941 taaagattgc atgccttcag aaccaaatgc tgcaccgaaa gttgttccta attctttaaa
    15001 tgaattacct aacgaattcg tttgccaatc aatggaactt aaatcaacaa cacccataaa
    15061 aataccaagg actgtggtcg ctacgatacc gataagaata gccccacgga cattttttac
    15121 aactaaaatg gctgtcagta ccaaaccaat cacagccaat aagataggag cgttgtcaaa
    15181 gttggctaac gcagggacga ttccaccatt tatcgtaaca tttgtcgctt ttccgccttc
    15241 aacgacagag ctcgaaatag ctgactggtc tgctgaaaaa gataagaatc ctgcattttt
    15301 gattccgaca tacgcaacga aaataccgat cccgccacca atcgcatgtt gaagactttc
    15361 gggaatcgcc cgaataatca tttttcgaat atttgtgaca gtaataaaaa tattgattaa
    15421 tccgcaaata aacaccattg ccaaggcttg ttgccaagaa taaccaagcc caaaaacgac
    15481 cgtaaaagtg aaaaatgcgt tcaatcccat accaggtgcc tgagcatatg gtacatttgc
    15541 gaacaatccc attaccagcg taccaataat cgatgcaatg attgtcgcta gaaatactgc
    15601 ttggaagggc atacctgatg ctgacaaaat cgtcggattt acgaataaga tataactcat
    15661 ggcaaagaat gtcgttactc ccgccattat ttcagttgat acatttgtat tgtttttctt
    15721 taaaccgaaa aacttttcca taaaaagttc cactccctga atttttttct gatggaaaac
    15781 tataataata aaaaataagt aaaatagggc aaatccatcg aacaatttca aattatatag
    15841 acgtttcatt cgcttttcaa cgttttttta acaaaaaaag cgaaaataat acttaacgtt
    15901 cgtgtttagc ttatgtttag ctatttatat agccataact gtagtttttg ttaggaatag
    15961 ctgattgctc ttgttaatta cctaaaatat gctagactaa aacaaatgct agttgaggaa
    16021 ggaaggaccc ttattgaata aaaaattaat tgccatcgat ctggacggaa ctaccctcaa
    16081 tcaagattcg atgattacat ctaaaacaaa agagactcta aaaaaagcaa tcaatgccgg
    16141 tcatcatgtc agtattgcta caggacgccc attccgaatg agccatcagt tttaccaaca
    16201 attagaatta acaacaccga tggttaattt taacggcgca ttagtacaca tccctaatca
    16261 gcactgggat ggtgaaagag aaacgttgat caatcgtgaa atcgcttttg aaatcttatc
    16321 gcaaaaaaag cagctaaatt tagattttat cgctgctgaa aatcgtgata ctttttttat
    16381 tgacagtttt gatttctttg atgaaaaaat ttttgcttct tctcgtccag gagagaagaa
    16441 tttgctttct cctaaaaatt tgacgacaaa tcctacatct ttgcttgtcc gaacagacaa
    16501 acgttttgca ggagctgtat ctgctgaatt aacacgtcaa tttggcagtt atgtcgatgt
    16561 tcggacatgg ggtggaccta ctgccatctt agagattgtt tcaaaaggaa tccaaaaagc
    16621 aaaaggcgtg caagagattg ctaactacct gtctatcgat caaaaagacg tcattgcctt
    16681 tggtgacgag cataatgatt tggaattgtt ggattatgca ggttggggag tagctatggc
    16741 taacggtact gaccaactca aaggcattgc aaatgatgtc actcctttga gcaatcagga
    16801 agacggttta gctgtttatc tggaaaaact acttaaacta taatagagaa ttagattcca
    16861 caaaaaagag gttgtgacaa tttt
//
LOCUS       DAPBBR010000051        16826 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPBBR010000051 DAPBBR010000000
VERSION     DAPBBR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.054"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(97..1824)
                     /gene="ptsP"
                     /locus_tag="RD488_002049"
     CDS             complement(97..1824)
                     /gene="ptsP"
                     /locus_tag="RD488_002049"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDT7658114.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(1824..2090)
                     /locus_tag="RD488_002050"
     CDS             complement(1824..2090)
                     /locus_tag="RD488_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDT7658115.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            2569..4803
                     /locus_tag="RD488_002051"
     CDS             2569..4803
                     /locus_tag="RD488_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7658116.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            4951..5271
                     /locus_tag="RD488_002052"
     CDS             4951..5271
                     /locus_tag="RD488_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7658117.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(5476..5700)
                     /locus_tag="RD488_002053"
     CDS             complement(5476..5700)
                     /locus_tag="RD488_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HDT7658118.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(5898..7478)
                     /locus_tag="RD488_002054"
     CDS             complement(5898..7478)
                     /locus_tag="RD488_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDT7658119.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(7879..9255)
                     /locus_tag="RD488_002055"
     CDS             complement(7879..9255)
                     /locus_tag="RD488_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7658120.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(9383..10501)
                     /locus_tag="RD488_002056"
     CDS             complement(9383..10501)
                     /locus_tag="RD488_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7658121.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            10643..11079
                     /locus_tag="RD488_002057"
                     /pseudo
     CDS             10643..11079
                     /locus_tag="RD488_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(11157..11690)
                     /locus_tag="RD488_002058"
     CDS             complement(11157..11690)
                     /locus_tag="RD488_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDT7658122.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(11784..12962)
                     /gene="mutY"
                     /locus_tag="RD488_002059"
     CDS             complement(11784..12962)
                     /gene="mutY"
                     /locus_tag="RD488_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDT7658123.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(12955..13752)
                     /gene="recX"
                     /locus_tag="RD488_002060"
     CDS             complement(12955..13752)
                     /gene="recX"
                     /locus_tag="RD488_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDT7658124.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            13859..15241
                     /gene="rlmD"
                     /locus_tag="RD488_002061"
     CDS             13859..15241
                     /gene="rlmD"
                     /locus_tag="RD488_002061"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7658125.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(15415..15993)
                     /locus_tag="RD488_002062"
     CDS             complement(15415..15993)
                     /locus_tag="RD488_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HDT7658126.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            16315..16785
                     /locus_tag="RD488_002063"
     CDS             16315..16785
                     /locus_tag="RD488_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDT7658127.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT         5050 a         3379 c         2953 g         5444 t
ORIGIN      
        1 ttttgtctat tcttactgac aaaaacgttt tcttaaaaaa gaacaaaaaa actggcgtag
       61 ctcttttaca agccacacca gcttttgata cgttgtttat tttacatatt catgaacaag
      121 ttcaacgact tcttccatca tatcgcattc tttcaatgca cgatcagcaa gttcagccat
      181 tttcgctgtg tccaagcgtt tcattaaact acgcgtttta agaatagatg tcgcactcat
      241 tgagaactca tctagaccca tacctactag caatggaaca gctgtttgat ctccagccat
      301 ttctccacac atacctgccc attttccttc agcgtgtgct gcatcaatta catttttgat
      361 caaacgtaaa attgatgggt tatatggttg gtacaagtaa gaaacgcgtt cgttcatacg
      421 gtctgctgcc attgtgtatt gaatcaaatc gttcgtacct acagagaaga aatctacttc
      481 ttttgcaaac ttgtctgcta agactgctgc tgctggaatc tcgatcatga tgccgacttg
      541 gatcgtatca gatacttcct tgccttcact tatcaatttt tgtttttctt cttcaaagat
      601 cgcttttgct gcgcggaatt ctttgagtgt agctaccata gggaacatga tacgtaaatt
      661 accatgaaca gatgcacgaa gcaatgcacg catttgtgta cggaacattt cgtcgccttg
      721 ttcagataaa ctgatacgca atgcacgata tcctaagaat ggattcattt catgaggtaa
      781 ttgcagatat ggtagttctt tatctccacc gatgtccatt gtacgaacaa ctacaggttt
      841 tccttccata ccttctaata cagctttgta agcttcatat tggtcatctt ctgttgggaa
      901 gtctggagaa tccatataca ggaattcagt acggtacaga ccaactgctt ctccaccatt
      961 attatggaca ccaactagat cttttggtgt tccgatgttt gcagctaatt caaaatgctt
     1021 gccgtcagct gtgacagttt ctgcattttt taatttttcc cattctgctt tttgtgctgc
     1081 gtaatctgca cctgcttttt caaattcagc tttttgttca tctgtaggat cgatgattac
     1141 atcgccttcg atcccgttga cagccaaaat atcgccttct ttgactttag cagtaatttc
     1201 ttttgtccca acgattgctg gaatttctaa agaacgtgcc atgatagcag aatgtgaagt
     1261 acgtccacca atgtctgtta caaacgcttt tacaaaattg cgatctaatt gtgctgtatc
     1321 acttggagtc aagtcatgtg caacaacgac cacttcttcg ttgatcattg atggatttgg
     1381 taaagtaacg cctaataagt gcgctaaaat acgtttagca acgtcacgaa tatctgcagc
     1441 acgctcttgc atataagcat tatcttccat tgcttcgaac ataccgatat acatatccgt
     1501 tacttctttt agcgctgatt cagcatttac gctgttgtct ttaatatttt gcttgatttg
     1561 acctaccatt tctggatctg aaagaaccat caaatgggca tcaaatactt gcgcttctgc
     1621 ttcacctaag ctttgcgctg ctttttcacg aatttgctgc aattcttcag tagatttagc
     1681 taatgcagca tccaaacgag cttcttcagc cgcagtatct tctactgttg ccttactgaa
     1741 tgttaaatcc ggttgaacta gcaggtaagc ttttgcaacg gctacaccgt cactagcggc
     1801 aatccctttt agcatttcaa ccattattca gataagcctt ctttcttcat tgtttcaacg
     1861 attgctgcca ttgcatcagc ttcgtcagca ccttctgcag taatagtaac atcagaacct
     1921 tgacctacac ctaaagacat aacgcccatg attgatttca agtttactga tttaccttta
     1981 tactctaagt ttacatcaga gttaaatttg cttgctgttt gtactaatag tgtagctgga
     2041 cgagcgtgga tcccagtttc tgctactacg tgaaattctt tcttttccat attaatcggt
     2101 ctcctttaag tgagtgttgt ttttatgtga gggttttctt ttttagtaat tcagagaatc
     2161 ctaacaaatg ccaccctttc atctgtaaag attaacattt tttttcgtta gatacaacag
     2221 ttttcattca atttcagata aaagtattca aattattccg gattcttttt catccttttc
     2281 ttcacatttt ataacaaacg tgtttatttc ctttttcttg tcgctttctc ttctcctgac
     2341 gtttatcatt ctttcctttg accctctttg ttttcatatg aaacgaatta cttgcttccc
     2401 tttttatttt tagtataata agagtcaaag gtcaggaatg gtcaatagag atttcacctt
     2461 ttctacctca taaatctctt aaaaaactag gggttattct tttacctcat gaaaaacgag
     2521 atgtaaaata tggatgtacc catttttgtg aaaggacgtg aatgattcat gctttgtcaa
     2581 aactgcggca agaatgaggc aacgattcac ttgtatgcca ctgtcaatgg tcagcggaca
     2641 caactcgatt actgtcagag ctgttatcaa aaaatcaaaa atcaacaaaa tggaggtctg
     2701 actaatatgg cccaaaatga tccatttgga tttggcagtt tggacgatct tttccgttcc
     2761 atgtctcgcc aaatgcaaca gcaaggaaat tatgagcaaa caccaccaac acaatttggc
     2821 ggaaacaaca acttcaatgg tggtcagcca cctcaaggca atacagaagg tttattggga
     2881 gaatacggaa tcaatatcac agaacaagca cgacaaggtg atatcgatcc tgtgatcgga
     2941 cgcgatgacg aaatcaaacg agtcattgaa attttaaatc gccgaaccaa gaacaatcct
     3001 gtcttgattg gagaaccagg tgttggtaaa acagcagttg ttgaaggttt agcacaaaaa
     3061 atcgtagatg gtgatgtacc gcaaaaatta atggacaaag aagtcattcg tttagatgtc
     3121 gtatctttag tccaaggtac tggtatacga ggacaatttg aagaacgtat gcaaaaattg
     3181 attgaagaga tccgtcaagc agaaaatgtg atcctattca tagatgaagt tcacgaaatc
     3241 gtcggtgctg gttctgctgg tgatggaaat atggatgctg gtaatatttt aaaaccagct
     3301 ttagctcgag gagaattgca aatggttggt gctactacct taaatgagta ccgcatcatc
     3361 gaaaaagacg ctgctttaga acgtcgtatg caacctgtac gggtagatga accaactgtc
     3421 gaagaaacga tcagtatttt gaaaggtttg caaaaacgtt atgaagacta tcatcatgta
     3481 aaatatactg atgaggccat cgaagcagcc gcaactttat ccaatcgtta cgtccaagat
     3541 cgcttcttgc cggataaagc catcgatttg ctagatgaaa caggttctaa gaaaaacttg
     3601 acgatccaaa tcgttgatcc taaaacaatc gagaaaaaac tgcaagaagc agaagaacaa
     3661 aaagttttag cttctcgaga agaagatttc gaaaaagcag cttattatcg cgatcagatc
     3721 aataaacttc aaaaaatgaa agaacgtcag ctcactgaag aggaaacacc tgtgattacc
     3781 gaaaaagata tggaaaaaat cgttgaacaa cggacaggta ttccagtggg tgaattaaaa
     3841 gaaaaagaac agacacaact gaaaaactta gcagatgact tgaaagctca tgtcatcgga
     3901 caagataacg ctgtagatcg agtagcgaaa gcgattcgcc gaaaccgtgt tggattaaac
     3961 aaacagaatc gtccaatcgg ctccttctta tttgttggac caactggtgt aggtaaaaca
     4021 gagcttgcga aacaacttgc ctacgaacta ttcggttcac aagattcaat gattcgtttc
     4081 gatatgtctg aatatatgga aaaacatagt gtctctaaat tgattggttc tcctccaggt
     4141 tatgtcggat acgaagaagc tggtcaatta acagaaaaag tacggagaaa tccttacagt
     4201 cttgtcttgt tagatgaagt agaaaaagct catccagatg ttttgcatat gttcttgcaa
     4261 atcttagatg atggtcgatt gacagatgca caaggaagaa cggtcagctt taaagatacg
     4321 atcatcatta tgacaagtaa tgccggaact ggtaaagtag aagcaaacgt tggttttggt
     4381 gcggcacgcg aaggtgttac tcgttctgta ttgaaccaat taaacaacta ctttacacca
     4441 gaatttctga accgttttga cgggatcatc gaattcagtg cattatcaaa agaaaacttg
     4501 atgacaatcg tcacactaat gctagacgat gtcaaccaaa tgctggcagc acagcaactt
     4561 cacatcgaag ttcctacgaa tgtcaaagaa aaattagttg acttaggcta tgatccatct
     4621 atgggtgctc gtcctcttcg acgcacgatc caagaacaaa tcgaagatgg tatcgctgaa
     4681 ttttatcttg atcacccttc tatccatgag ttgaaagcaa aactggataa agatggaaaa
     4741 atcatcgtta cttctaaacc agaacgtttg gctaaagaat cagccgaaga aacggctgaa
     4801 taaatccagt tttatagcgt gagacggtat ttctttgaga aatgccgtct cattcttttt
     4861 tcagaaaagt caaaatactg ttcattttat aaaaaagaaa ttataataag agaaacaagc
     4921 aattaaaaat acataaaaga ggtgagcgcc atgaaattgg taaatgtaac aaacagccat
     4981 tcccgtcttg tattaaacca gcttgaaaac actgatgccc atctagtcaa ggtctacaca
     5041 gccggaaata ccactattgt ctacactgaa gcccctgaac ataatgaaat tctgctgatc
     5101 aatgacaaac gtaaaatcca gccgaaagaa atcgaagatg ctaaaaatta tttcttagat
     5161 aaaatcaaag acgccgttta ccacgaggat gaaatcaaag taatcgaatt ggcaggcctt
     5221 gttgaaatct cgattccaaa acatgaatta ggcgctacat tagccgtgta aacaaatttt
     5281 gaacataata attaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
     5341 acacgtataa acggcgaaag cagaagcaac tccttcggaa ataagctgaa attcacgaaa
     5401 attgcttttc aaatttttgt gaattccagc ttatttcttg gagttaaacg cttctgtctc
     5461 agcctctttt tctttctagc tttttgattt ttctcttttc ttttgtactt ttctcttttc
     5521 attttcagtt ctacgcgtgt ctttattttt aactttttcc tctttatgga tgattgatcg
     5581 tactttttgt gcaatttgct cgtttttgtc ccagtctttt acatctaata atcgacataa
     5641 tcgtaacatc tcttcttttt tctgtttttt tctttcacgt ctttgccatt ctgtttccat
     5701 gtgtcacact ctcctttctt taatcatatg tacgcaaaat aatttttata tttttttgat
     5761 tagacatttc tatgatttta atatagtaaa aagagccgtc acggaaaatc cgtcacggct
     5821 ctaaacaaaa tatgagaggc tgtttttgtt tggctattct tattacttga tgcagggcag
     5881 cttgtgtcaa gacttcttta catcaaactt tttaatttta cattgggata tttatccgca
     5941 aaccagcgtt ctgcaaattg gttctcgaat aagaacaacg gttggtcgaa acggtcacga
     6001 gccaagatat tgcgacttga actcatcttc tcatccaaat cttctggatc gatccagcga
     6061 gcgattttgt gtcccattgg agacatgatt acttcggcgt tatactcatt taacatacga
     6121 tattggaata cttcgaattg tagctgacca acagctccaa tgatatattc ttccgttaga
     6181 tatgttttat aaagctgaat cgctccttct tgaactaatt gatagattcc tttgtggaag
     6241 gatttttgtt tcatgacatt ttttgcagtc actttcataa acagctctgg agtaaatgaa
     6301 gggagttctt cataagcaac ttttagtttt ccttcgaaca atgtatcccc aatctgataa
     6361 ttgcctgtat catatacacc gatgatatcg cctgctactg ctttttcgac gttttctctc
     6421 gaatctgcca taaattgtgt gacattgctt aatttcagtt ttttatttgt acgttccaac
     6481 cagacatcca ttcctcgttc gaatgttcca gaacagattc ggacaaaagc gattcggtca
     6541 cgatgggctg gattcatatt tgcttggatc ttgaatacga aacctgaaaa ttcttcctca
     6601 taaggactta ccatctgatc atcttgtgtt ttgtgtccat aaggagctgg tgccaattca
     6661 acgaaagtct ctaaaaaagt ctgtacaccg aagttagtca atgcagaacc aaaaaatact
     6721 ggtgtctgat cgccacgagc aattttttct tgattaaatg catctccagc ctctttgatt
     6781 agttctactt cttctaagac ttgttcatat aaggaatttt cagttagagg atgattttcg
     6841 ggaagcagtc catcttcatc caattctact aatcgttcat cctgataatt ttccggacga
     6901 taaaactcta cacgattatg gtagatatca taaagacctt ctagcccttt acccataccg
     6961 attggccaat tcatcggata agattcgata tctaatagct cttctaattc ttctaacaat
     7021 tccaatggtt cacgaccatc acgatctagt ttgttgataa aagtaaatat cgggatgcca
     7081 cgttttttta caacttggaa taatttcttt gtctgtgctt cgatcccttt tgcactatcg
     7141 attaccatga ccgcactatc cacggccatc aaagtacgat aagtatcttc agaaaaatct
     7201 tcatgtcctg gtgtatccaa gatatttact cgtttccctt gataatcaaa ctgcataaca
     7261 gaactagtaa cagaaatccc acgttgtttc tcgatttcca tccagtctga tttggcaaaa
     7321 ttacctgttt ttttgccttt tacggtcccg gcttgacgga tagccccacc aaacaatagt
     7381 aattgttctg taatcgttgt tttcccagca tccggatggg aaatgatcgc aaaagttctg
     7441 cgattgtcca cttgttgctt taattttgga ttattcataa cctaactcca tttcttccat
     7501 tcaattattt atattttctc taggcacaga ttgtccgatc tcttaaagaa agacaatttc
     7561 atatagggct gtgacaaaag ccgtgtagca gtctcttttt ccgagtaaac ggcgttctag
     7621 agacagccta tcagcaataa gcccacccaa gccaaaaata cgaaaagctg tttttgcttg
     7681 gctgctctta ttacttaatg caggatagct ttttcacaac ctttgtcaac tactacaact
     7741 gaatcagtat agcatggatt cagcgaatga aaaagccacc aaaccataag agtcaaatat
     7801 ttttttgtca gctgactaaa agaaaagacg tgttgcttgt ttattcaagc aacacgtctt
     7861 tcataaccaa gtttccaatt atcttcttgg ctcgtcatct tcgaattctt ttctgaagta
     7921 tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga tcatgaaaaa tgacacggat
     7981 tttaaggatt cgagaacctt ccatttcttc agaaaccagc gtaatattat cgacatcaaa
     8041 cgataacttt tcgccttcat ccggaatcat gcctaatgct gtaatcaaat aaccagccat
     8101 cgtatctaca tcactcatat gcagatcact gtcaaaagct tcattgaact catcaatcag
     8161 catacgtcct tggatgatat attcgtgttc atcgattttt tcataaagat tctcaacttc
     8221 atctgattca tcatcgattt ctccgacgat ttcttctaaa aggtcttcta gtgttgctaa
     8281 cccaacgacg ccgccatatt catctaataa aatagccatc tgattctgcg tctttttcat
     8341 ttcatataac agatcatcaa taaagaccgt ttcaggaacg aataaaggct cctgcatgat
     8401 tttcttgata tctaaattat caaagccgaa tttatgggca gcttttagta aattctttgt
     8461 atgaaggatt ccgactactt tatctttgtc ttcgttataa acagggattc ttgaatagtt
     8521 ttcggataaa acttcattca cattttcttc cacagtgtcg ttgatatcaa tcataaatgc
     8581 atccgttcgt gggaccatga cttctcgggc aactttcgta tcaagagaaa aaaccccttg
     8641 gagcatttct aattcttcat tattcaatac gccttcgttt tcaagcatat aacgcatttc
     8701 atctctggtc atttttgaat cttcatcatc aaaagtcatc ggcgtgatac gcgccaataa
     8761 acttgtggaa gcagaaagca gccagacgaa gggcttagct actacaccaa tcaagcgtat
     8821 cagccctgaa gtgaactttg cgacttcttc tgatttattt aaagcaatac gtttagggta
     8881 caattctcca aaaacaatcg atacataggt caaaatagcc agcacaatga tatttgcaat
     8941 attttttgcc gctgtgccgc cacctaatac cggagctaac cgttccgata aagtattagc
     9001 tagtgaagca ccagacaaaa tgttgaccaa agtgattcct acttggattg tcgataggaa
     9061 attatttgga ttctgcaata tttttaaaag cttttgagat ttcacatctc cttcatcagc
     9121 tttttgctcg attcgattct tattgatcga aacaacagca atttcggaag ctgctaaaaa
     9181 agcattgatc aatgtcaaaa cgatcaataa taaaatctgc gctaacagcg actgactctc
     9241 agggtcagca ttcataatcg cattctctcc ttataaaatt aatttttagt ttacgataga
     9301 aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca aagcaatttt ctttgcaata
     9361 aaaacaagtg tactaaaact acctacgagg tcgtagcaat tttcttcttg ttttcatttt
     9421 gcttgtcttc tttgacgatt ttgattatat aggaaatgat cgtcttgcag attgcgtaaa
     9481 aaggaacacc taagaagata ccaagcaatc cggcaatatt tccagctact agaagaacga
     9541 taatgatcgt taatggatgg attttcagtg atttcccaat tacattagga taaatgatat
     9601 tcccatccaa ctgttggacg attagcacaa ccacacaaca aagtaatgct tttaccggat
     9661 cattgaagac tgttactaga aatgcaggtg ctagtcctag ataaggtcct aaatatggaa
     9721 ttaggtttgt caatcccgca atgaccccaa ataagaaagc ataatccaca ccaattacca
     9781 tatatcctaa aaatgtgaag gtaccaacga ataaacattc gattgcttgt ccgctaatgt
     9841 aattagccaa tgttttattc agttgcccca ataactccac aatttggttt cttctttttt
     9901 ctgggaaaaa ctgttggatg tttggcacta gtttttctcc gtctttcaac atatagaaca
     9961 agatgaatgg tgctgtaatg attactacgg ttgccgaagc gatcgttcca acgatcgaac
    10021 ctaaactatt ggatactcca ctaaggaatt gctgaatgat tgtcccgtaa gaaatgtcta
    10081 attgctcaaa atatttattg atatctactt ccttgaacaa aggcaattcg gctacctctt
    10141 ttaaccagct ttctacctgt ttgatgaaat caggcatatt agatgccaat gaggaaattt
    10201 gctgtactag acttgggatg acactaagta aaatccaaat aattgctgca actaaaagga
    10261 gcagcacaat tgcgacagcc catattcttt tgatttttgc tttcatcaac agcttgacaa
    10321 taggattcaa taaatagtaa agaaagcctg caatcagtac aggtgcaaat aacgtggaaa
    10381 aaaatgtccc gatcggttcg aaaataaagt ttatttctga tgaaatcatg atcaatgcag
    10441 ctatgatcaa taattcaagc gaccaaaaca ttagtttaga ctgtctaagt ttttcaaaca
    10501 atagatttcc tcctttcttt cttactagta tatattatat tcgttaaaaa ttcttttatt
    10561 ctttttttat ttttgaaaac ttgccatact ttttatttgt tttattttcc agtatactat
    10621 acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca aaagatacaa tgagcaatat
    10681 ttacttagat gctgtacgga tcaggcatca agtttttgta gtcgaacagg gtgtgccttt
    10741 gtctcgagaa atagacaaag atgaagccca ttgtatccac ttcgtcctgt actcagataa
    10801 aaaagaaccg caaggaactg tgtacgtctt ttgcctttag aaaacggaaa aatgaaatta
    10861 cagcggatgg cgattctttc tgaatacaga caccaagggt taggaaaaat attgattgaa
    10921 gaagcagaaa actttgctaa gaatcaaggc tataatacga ttttattagg ggcacagtcc
    10981 acagctgaaa ctttttacga aaaactagga tatacagctt acggcgatcc ttttgaagat
    11041 gctggcatgc ctcatattta tatgaaaaag actttataaa aatttatttc gaaaaaagca
    11101 aaaaacagca agcttttgag aaaaatctct cactggctta ctgttctttt ttgtgtttac
    11161 ttacgcgaca attgcttgta acggttatac caaatatcaa tatagccttc cgagaacggg
    11221 ccatctccat tattgatcca gtcaaccaga atcttcacat tttcttttag gatgaagtca
    11281 atatcgttcg ggtaattcat cattttgctg tgcatctcat attcatcgac atccaatagt
    11341 cgtttctcgc cgtcaggaaa taccttgata tccaagtcat agtcgatata tttcaaggcc
    11401 tcatcgtcca gcaaaaaagg tgaagctaga ttacaataat aggaaacccc cttttctctg
    11461 atcattgcta ttacattgaa ccagtatttt ttatgaaaat aaacaatcgc tggttcgcgc
    11521 gttacccatc ggcgtccatc agattcagtg actaatgtgt gatcattcac gccgatcata
    11581 gagtgttcgc ttgtttttaa taccatggta tctcgccacg ttcgatgcaa tttgccgtcg
    11641 tgcttgtaac tttggatcgt cacaaactct ccttcttttg gaactcccat agcaaccctt
    11701 ccttaagcag cattttgtgc tttgtgtttg ggtgttcatt acaccgacat cataattatt
    11761 atatcaataa aaatgagctt tgcctagaaa ggattcctat tgtttcgatt tttctctaac
    11821 tgatctacca gtttcatttg gaccttagga aaaacgaccg aatcaaatgc atcaggcttc
    11881 aaccacttcg aagttttgtt ctcggtaaat tcttgttctg ctccctcggt tgcccgtccg
    11941 taaaaaagga gaacatgcca tttcagatga ctaaaaatat gagtaacttc tcctaaatgt
    12001 cgtgtctgcc aaacaaagag ttcctgcttt tcaaatggga gattttgctc ttcttctgct
    12061 actaggtcat caaacagatc gatttctggc tttgtttccc attctttttt caatcgctca
    12121 tactcctctt gtgtcacttc catcattgga aatgtccaca tattcgccag caatttttgg
    12181 ctatctcttt cttcaaaata atacgctcca gaatgatttt gaagagctgc actgatataa
    12241 taaacgtctt ttggctttgc tttttttgtt tttacaggaa aactcgtttg gattcctcgt
    12301 ttgttagcta aacaaaaggc ttggatcgga caagtctcac actttggaga agttggtgta
    12361 cagatagctg aacctagatc catcattgct tggttgaatt cacctggatg cttttcatca
    12421 atgattttcc gcatcgcttc atcaaagatt ttcctgctag aagcttttgc gatgtctgct
    12481 tcaatgcaaa acaatctgct gactactcgc atcacgttgc cgtcaactgc aggttctgga
    12541 agtccaaatg cgatacttgc aatcgcgcct gtcgtatatg gtcctattcc cttcaatgag
    12601 ctaatttctt caggcgtttg cggcatttcc ccatcaaatt ctgacatgat ctgtttagca
    12661 gcagcttgga tgttccgggc tcttgagtaa taaccaaggc cctcccatgc ttttaaaagc
    12721 ttttcttctg gagcatttgc tagctcttca attgtaggaa accattccat gaaacgataa
    12781 aaataatcga tcactgtgtc tactctggtt tgctgaagca tgatctcaga gatccagata
    12841 cgataaggat cacgattata gcgccaaggc aggtttcttt tttcttgttc ataccattga
    12901 atgaactgat cttgaaattc ttttgtttct ttatctgtcc atttttccca ttctttattc
    12961 actttcctct tccttttccg taatgaatcg ctggatcata tccaaatcaa atcctttttg
    13021 atataagctt tgctttactt ttagatttct ttttttaggt tcaaacctta aatttcttcg
    13081 ccatagttta tctccttgtt tgactaaata atcatattct atttcttgat ctgcttcttg
    13141 cggaagatca gctatcgctt gttggatcac ttcttgagaa aagcctttcg tcatcaatgt
    13201 ttgttggatt tttctcaata attctttttg gctttttccg tgattttttc caaacgcttt
    13261 ttcggctgtc tgatgtgcat tttgaacttg gtcttcaaat gtatattggc tgagcgcttg
    13321 ttcaatgatt tcaggtttca aacctttttg ctgcatctgc tgcgctaatt tctttggtcc
    13381 tttgtcactt aagcgcatat tcgtgcgcac ataactttcc ccatagacca aatcatcgac
    13441 aaggtccaat tcttttaagc gggctacgat tttatttcga tcttcttgaa ggatttcctt
    13501 ttcttttaag tatgttcgga tttctttttc cgatcgcaac tgataactta agtaattcat
    13561 tgctaggtga aaaccgaaat cagctccgct actcttcttg atctcttgga tagtttcttc
    13621 gtctaattcc cgtcctttta ataatcgata gcgtactaat acatcttcag atacttgtaa
    13681 agcttctcct tcagataaat ctacgcgata gaaagggcct ttgcctttac tgattctcgt
    13741 aacggttaac ataaacatcc tcctcgaaca tatattctct atcataccac agaaaatccc
    13801 cgtaatcagg tattatatgt tagaataaac cacagaaaaa agaaaaaggg agatacttat
    13861 ggcagaaaca attgtcaaaa ctggacaaac ggttcctttg aaaatcaagc gtttaggcat
    13921 aaatggtgaa ggaatcggtt atttcaaacg gttgatcata tttgttccat atgcactacc
    13981 aaaagaagaa gtactagtga aaatcacgaa agcaactcct cgctatgcag aaggagaatt
    14041 aataaaagtc aaaaaaacaa gcaaagatcg cgtagtggca ccatgtcctg tttactatga
    14101 atgcggtggc tgtcaattac aacacttagc ttatcaagct caattggatt ttaaaaagga
    14161 tctgcttttg caagcattgg aaaaattcaa accagcaggc tttcgatctt atcaactttt
    14221 gccgacgatc gggatggatg agccttggca ttatagaaac aaagcacaat ttcagttacg
    14281 aaaaaataag cagactcaaa aaattgaagc tggtttatac gaagcaaact ctcatcagtt
    14341 agtccctata acagactgct tggttcaaga acctcgaaca caaaaagtaa tgaatactgt
    14401 tgttcaacta ttgaataaat ttgatgcacc catctatgat gaacggacaa acagtggaat
    14461 cttccgcaca atcatggtta gaatcggtgt taaaactggg gagttacaag ttgtttttat
    14521 tactcgcagt aaaaaattcc cgcaaaaaaa cgcaatgatc cgtgagatca atgaacgact
    14581 gcccgaagtt gtttcaatca tgcaaaatgt ccaggcacaa aaaacgtctc tcgtgatggg
    14641 ggatgaaacg atccacttat ggggaaaaga agccattgaa gaacaaatca atgaagtgac
    14701 tttcgatctt tctcctcgtg ccttctttca actcaatcct cagcagaccg aattgcttta
    14761 tggcgaagga atcaaagcat tagatgtcca gcctaatgaa acgatcgtgg atgcttattg
    14821 cggagttggg acgatcggct taagtgtagc aaaacaagcc aaagaagtac ggggaatgga
    14881 taccgttcct caagcaatcg ctgatgcaaa aaaaaatgcg gaaagattag gatatcacaa
    14941 cactcgatat gaagtcggga cagcagagca agttctgcct aaatggttga atgaaggttt
    15001 tcagcctgat ggtatcatcg tagatccacc acgtacgggt ttggataacg cattgatcca
    15061 atcattattg aaataccctc caaaaaaact tgtttatatc tcctgtaatg tttctacact
    15121 tgccagagat ctggttaatt taagtaaaaa gttcaagatt gaatatttac agtccgtcga
    15181 catgtttcct cagactgcac gttgtgaagt tgtcgtgaag atgacgagac tcgctgacta
    15241 aatgaaagag gttgtgaaaa agtctgccct gtatcaagta ataagaacag ccaaacaaaa
    15301 atagctcttc atgttttatg aatactgtac ttgtgaccga agagttaaca ggaggacact
    15361 atttatttaa aaaaagggtt gtgacatagt ttttgtcaca gccctttttg attattattg
    15421 gatattcacg tctatcactt gataaaatgc atttgtcgta tcgctgatat tccatactgc
    15481 taaaatcaca ttatatcctt ttcgatcctg cggaagtgtg atcgtttggt tgactgtttt
    15541 tggtggaaca gttgctttgt cgtctatttt tgtgatcaat tcaaaatcac taaatttcaa
    15601 aggttgatta ggattccaag ttggtttggt aatgtagtaa tcccaagtac ttgtccgatg
    15661 ttgtgctgtt aaattccaag taatatttaa tgttcctgga ttaaccatgt ttttatgcca
    15721 tctgttagat gtctgttcat ctaaaggctc aaagccgctg actcctgcac tagcaatttt
    15781 tccatcaatg aatgtatttt tggtagcttc gatactttgc ggttcccatt gtgctcttcc
    15841 gacattttga tttaagtttc ctgctgctga tgttcctagg tatgcacggc ttcctggaga
    15901 agtaatataa ccatgcgcaa aacctggaat gctaaaaccg aacaacccta aactaactaa
    15961 cccaataaac aataacgtac taatcttttt catgtagaaa cctccttcat ttgataacca
    16021 cattgtaaac gctttattgt attaacacaa acattatgct tttataattt tatgttgaag
    16081 taaaaaaggt gaaaaaagta agatgcagat tataacagaa gtagacgaga aaagtacaaa
    16141 tagaaaacat gagaatcaaa tcatatgatc tttttcaaaa acatcattca tataaacaaa
    16201 tgttcaactt tttaataaca acaattatca atttttttct tacttcacaa actaaataca
    16261 ggtcttgctg tgagccttca tggtaaacta atattataga aaggagttag taaaatgaag
    16321 atgataaaag atattcgttt ttgggtttgt gttataggaa ttgtcatatt aggcttttta
    16381 tcagggttgc ttagcggaaa tcccggaaaa tattactatt ctttgcaact tccaccattt
    16441 gcaccaccta gctggatatt tgggccgatg tggaccttac tgtatatatt gatgggtatt
    16501 tctctttatt tgttacttaa tcacaacaac aaaaaacagc gaaacaatct tgtcggtctt
    16561 tttgtgattc agttcatttt taattttata tggtctgctc tattttttaa tttaagaaat
    16621 attttcattg cagcaatcga tattacactt ttagttattt tcttgtcagt gcttatgtat
    16681 cagttgtggc tgcatcatcg cctggcaatg tggctcatga ttccttatta tttatgggta
    16741 ctattcgcaa ctctattgaa ttattcaatt tattttttaa actaagcgct aaaaagagac
    16801 gtcctgtaat ttaacacata gaaaaa
//
LOCUS       DAPBBR010000052        16615 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPBBR010000052 DAPBBR010000000
VERSION     DAPBBR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.055"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="RD488_002064"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="RD488_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDT7658128.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="RD488_002065"
     CDS             complement(680..1666)
                     /locus_tag="RD488_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7658129.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="RD488_002066"
     CDS             complement(1689..2255)
                     /locus_tag="RD488_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDT7658130.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="RD488_002067"
     CDS             complement(2269..2685)
                     /locus_tag="RD488_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7658131.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="RD488_002068"
     CDS             complement(3142..5076)
                     /locus_tag="RD488_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7658132.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="RD488_002069"
     CDS             5357..6313
                     /locus_tag="RD488_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDT7658133.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="RD488_002070"
     CDS             6403..7506
                     /locus_tag="RD488_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDT7658134.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="RD488_002071"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="RD488_002071"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDT7658135.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="RD488_002072"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="RD488_002072"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDT7658136.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="RD488_002073"
     CDS             complement(10887..12140)
                     /locus_tag="RD488_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7658137.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="RD488_002074"
     CDS             complement(12146..13069)
                     /locus_tag="RD488_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7658138.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="RD488_002075"
     CDS             complement(13290..15782)
                     /locus_tag="RD488_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDT7658139.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="RD488_002076"
     CDS             complement(15789..16256)
                     /locus_tag="RD488_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDT7658140.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="RD488_002077"
     tRNA            complement(16392..16465)
                     /locus_tag="RD488_002077"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="RD488_002078"
     tRNA            complement(16523..16596)
                     /locus_tag="RD488_002078"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4907 a         3475 c         2958 g         5275 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg atggcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtcttg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAPBBR010000053        16564 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPBBR010000053 DAPBBR010000000
VERSION     DAPBBR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.056"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1..634)
                     /locus_tag="RD488_002079"
                     /pseudo
     CDS             complement(1..634)
                     /locus_tag="RD488_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            1119..2753
                     /locus_tag="RD488_002080"
     CDS             1119..2753
                     /locus_tag="RD488_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658141.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(3020..4189)
                     /locus_tag="RD488_002081"
     CDS             complement(3020..4189)
                     /locus_tag="RD488_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7658142.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVDHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            4393..5568
                     /gene="mltG"
                     /locus_tag="RD488_002082"
     CDS             4393..5568
                     /gene="mltG"
                     /locus_tag="RD488_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDT7658143.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5704..6183
                     /gene="greA"
                     /locus_tag="RD488_002083"
     CDS             5704..6183
                     /gene="greA"
                     /locus_tag="RD488_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDT7658144.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            6352..7083
                     /locus_tag="RD488_002084"
     CDS             6352..7083
                     /locus_tag="RD488_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDT7658145.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            7080..8147
                     /locus_tag="RD488_002085"
     CDS             7080..8147
                     /locus_tag="RD488_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7658146.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            8154..8786
                     /locus_tag="RD488_002086"
     CDS             8154..8786
                     /locus_tag="RD488_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7658147.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            8926..9591
                     /locus_tag="RD488_002087"
     CDS             8926..9591
                     /locus_tag="RD488_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDT7658148.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            9619..9912
                     /locus_tag="RD488_002088"
     CDS             9619..9912
                     /locus_tag="RD488_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HDT7658149.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(9980..10927)
                     /locus_tag="RD488_002089"
     CDS             complement(9980..10927)
                     /locus_tag="RD488_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDT7658150.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(11105..11908)
                     /locus_tag="RD488_002090"
     CDS             complement(11105..11908)
                     /locus_tag="RD488_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HDT7658151.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            12054..12968
                     /locus_tag="RD488_002091"
     CDS             12054..12968
                     /locus_tag="RD488_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7658152.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            13016..13486
                     /locus_tag="RD488_002092"
     CDS             13016..13486
                     /locus_tag="RD488_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDT7658153.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            13571..14179
                     /locus_tag="RD488_002093"
     CDS             13571..14179
                     /locus_tag="RD488_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDT7658154.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            14313..14513
                     /locus_tag="RD488_002094"
     CDS             14313..14513
                     /locus_tag="RD488_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7658155.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            15267..16493
                     /locus_tag="RD488_002095"
     CDS             15267..16493
                     /locus_tag="RD488_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7658156.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         5599 a         2518 c         3203 g         5244 t
ORIGIN      
        1 aggtaaaaaa taagtctgat tccttgtctc taaaggcttc ggtcagctca tggaaaaaag
       61 tataggcgtc ctttaaaggc gttgaaaatg ccagcaatcg atcaatcatc attgcttcag
      121 tgagtagcgg gtatttaggt gcacgaaaac tgcgccatgt tttgtaatca tagtgattga
      181 ttttttgacg gttttttaga agaaagcgcc agttcttttt cactttctcg gcttcccgtc
      241 gttgccctaa ctggtgtaat cttttcattt cttgtacacg aaaatcattg aacgcctgat
      301 tcaaatgttt gatgatatga aaacaatcaa tgacgacttt cgcatttggt aagacacgtt
      361 ttgtcagttg gaagtaggcg gcgttcatat ctgtcactaa atattccacc gcttcaggat
      421 ttgcacagcg actaaaatag tgtgttaatc gagacaattt tcgtgtaggc aaaatatcaa
      481 tgagttttcc agtctcgcca tccgcacaaa taaagctcat tttatccaca attgaagcgt
      541 gcgaacgaaa ttcatccacc atcaatactt ttggcagggt cctttttgac ggcttcggaa
      601 gatagttttt caactctttc aatgtacgaa tcatatacct aaaataacaa tgggactgaa
      661 gaatcaattt tgattcatca gtcccataaa ttatagagcc tatattttgc gaattgcgct
      721 acggtttctt cttttctttt gtctgtaata tgaatatata gatccataat gatttgaata
      781 gaagagtggc ctaaacgctc ttgcacatct ttaatatttg cactagcttg ctaaaagcaa
      841 gctagcatgt gtgtgtctaa gaccatgaat agtaattcgt ttaagattgt ttttcctgat
      901 gattacatct aaccattttc gagatttaga taattgaagg tgttcatttc tttctggtaa
      961 aaatttaaat atataactac attttctcta ctaactttga aacactactt ttgtaatata
     1021 aaaaatattt tattaataat aaaattaatc acattttata tagtgactaa tctagtgttt
     1081 taaaaaaata aatgatacta tatgtaatat aaaaaaacat gaggtggtat atgaatttga
     1141 aaaaaatttt ttctgtaaaa atatttatag tttatgcatt tgttagttta ttatatttat
     1201 ttccagcatt taaaaacatg gaaatatttg gcttttatga tacggcattt cacattaatc
     1261 gtgcgttaag tttagaatct atttttagct cccctattaa ttttgaaacg tttagatcat
     1321 atggcatgca agtaaataat ttttacccat ggttaactct atatccttta tttttattga
     1381 tcaagtttac taatttagca ataggctata acctttttct ttatattgtt acgctcatta
     1441 ctctatttat atgtcattat gtaatgtatg aaattaccaa aaaacatgtt actagctcct
     1501 ttttcgctat tatatataca acatcttctt ttaggagtgt agaaatattt cttcgagggg
     1561 caatggggga attactcgca atgtcaatac ttcctcttat tttactcggg tttataaagc
     1621 tttacgactc aaaaaaagaa tcttgggtta tgttggcgat tagcatgact ttattaattt
     1681 acactcatgt tctttctgta gctatgacta tggtaatgat tataattgct ttaattattc
     1741 aattttatcg gaaaaagaaa atagaaatct tcttaattat taaattaata aaagctgcta
     1801 tagttacttt acttctttca ctagcgttta taggtcctat gattgagcag acattgtatc
     1861 aagatctgaa tagaccttat gtggatatat tacaaaaaag agcaatttat ctgggtaaag
     1921 agtttttgat tggaagtata gattcagaat tactatcatt tggtattggc ttaactttgc
     1981 ttatttgttt aattatacta acatttaact ttaaaaaatt aggaatctta tctaaaatca
     2041 cttatataat gggtataata tctattctac tttgtacaaa aatatttcca tggtttgcct
     2101 tacaaaatac tcctttaaat attattcaag ctccttggcg ttttatgata ttttcaacat
     2161 tgttcatatc tttttcagta tctctattta tttctccaca gttggaaaaa ttttcttata
     2221 caaggagaag aaattttata ctattattaa tattagctat ttcaatttta aattattcat
     2281 cagtagttaa catggtgaaa gaaatgaatt ttcaaggaac ttattctaat gaacaaatgg
     2341 aaaataaact tgaagaattt gagaattttg attatgtacc tataggctat aaaaaagatc
     2401 aattgctttt gaaaaaccat caagttacag aagatggtca agttatttat agtagctttt
     2461 ctccaaataa agatgaaatt acatttacgt ttaaatcttc aaaaggcaaa acaatagttt
     2521 tacctgtatt ccggtataaa ggattaacgg ttactgttaa ttcaaaaaat gctacagtac
     2581 taaaacaagg aggtcctttt gttacagtaa aaagtgaaag tggaataaat aaagtaacaa
     2641 tcaggtattc atacacattt ttttctaaaa tctcattatt tatttctata atcacgctaa
     2701 ttgttcttct tttttattgc ataaaattaa aaataagaac aagccatgaa tgatttgcta
     2761 gcacatattt tagcaatcta aagatactat tttagattta ataggccctt tgtcaaataa
     2821 tgttggtaaa gagaaatctt agaataattt ggacagaaca gaaagaagaa cacctctttc
     2881 tgttctgttt atttggaatt aaagtctgta gcaaaaattg atttttagat ttgtcccaca
     2941 ctctttccta cgtttagtcg agtacttttt ttaagcaaat gctattcaaa gaagtagtat
     3001 ttgctatctt ttcatcatat cagctatttg ccaacttagt agttccttcc atcaggtcat
     3061 agatttggtt tcttagatca gcagtaggca gtttgatagt tttgtcagct tttatattgc
     3121 tttccatgat gatagcatcc tgtgaatctt tgctaaatat agcagatgta tcaaaagagt
     3181 cgatatttcc ttgcgacagg atataattat ctccgctata taccccacca ctatatggat
     3241 gtccattcgc attttcacgc cataatgaga agagtaagtc tttggaaact agttttccag
     3301 ataaaacttg tgtaaacagc gtatttaaat catagacgga catactgata ttaccagtcc
     3361 ctaattcgtt atggatctct gtttcagatt ctgtcagtgg tttaaagtaa tcatcctctt
     3421 tagacatttg ataggatagt gcatgattgg atgaattttt gacttggtca taaaattttg
     3481 tatgctgtaa tcctaaaggt tcgatgatat catcggtcaa taatttttca tacggttgat
     3541 ttgttaattt gatcaaaatt ccagtcaata tggtaaagtt caatgaatca taatgagagg
     3601 tctgataatc tgtaaatttt aagtgctgaa tcgcaaattg aacgacttct tcatcagtca
     3661 tcggtatggt tggagaagca gttcggtgca agcctgagcg catatacagc aagtcacgga
     3721 tagtaatttg ctggctgcca gcaatttgtg gatagaattg agccagctta gtatctaaag
     3781 aaaggtgccc acgctcgact tgttttaaaa tcaaaagagt agtcaatgct ttttgaaccg
     3841 aaccaatctg ataataaaga gaaggatcat ttggttgttg cgtgagttta ttcgcatagc
     3901 catagccttt ttccatgatg atgcgattat ttttctttac gtaaattgag ccaatataat
     3961 cattttttct taatagttga tcgatttttt caacgagctg ttgttcattg gtagtcagta
     4021 tcaacttttt ttgagctgat tgagcatggt caactatctg agagtgttca ttattgtaaa
     4081 attgccatcc aagaatagtt cctgtagaga acgcactaag gctaaacaac acgacaacga
     4141 tcattaaaaa tgaatatttt ctttttttag catgttttcc ttttttcata atagtttatt
     4201 tagtctcctt tcttttttac agaaagaata aagctaaaat agcttgtatc ttgataacat
     4261 ttattttaat cttatagtaa tggatttact acttacattt ttgatagaat atttaaataa
     4321 aatcattcac gccaattcaa atatcatgta taatgaataa agttacgaac ttgatagtaa
     4381 ggaggagttg ttttgtcagg aaacaaacaa cacccaagta aagataaaaa agaagccagt
     4441 aaggcagcta cagcagatat aatcgacaag cggagaaatc tgcgtaaaaa agaagataag
     4501 attgtgagga agatcatttt agtgattgct cttacattat tgattattgg cggatttctt
     4561 ggatttaccg tgtatcgtta tgtagatagc gggttgaagc ctttagataa atcagatgac
     4621 caattagtcc aagtcgagat cccgagtggc tcttctaaca agcagattgg tgagattttg
     4681 gagaaggaca atattattaa aagcgggatt gttttcaatt attatacaaa atttaaaaat
     4741 ttaactggct ttcaagctgg ctattatcag ttagcgccta atatgactct tgacgagatt
     4801 ggcaaacagt tgcaagaagg cggtacttct gagccaacaa aagttgcaga tgggaaaatt
     4861 gccattccag aagggtacga tatcgatcag attgctgaac gggtagcgaa ggtaactggt
     4921 aaagacaaga aagaattttt agatttagtg aatgatgaga ctttctttaa cgagttgcac
     4981 caaaaattcc cagaactgtt ggaaagtgca tctaaagctg agaacacaaa ataccgtttg
     5041 gaaggttact tattcccagc cacatatgat tattacacga gtacttcgct taaggatcta
     5101 gtgattgaaa tggtgaacaa gacgaatacg gtcatgcaaa actattattc agctatcaag
     5161 cagaaaaatt tgactgtaca agaagtttta actctagctt ctctagttga aaaagaaggc
     5221 gtaaaagaaa atgatcgtaa aaacattgca caagtcttct ttaaccgaat caaagcaaat
     5281 atgccacttc agtcagatat ctctgtttta tacgcattag gtgaacacaa agaattagtg
     5341 acgtatgaag atacagctgt agattcacca tataatttgt ataccaatac cggctatgga
     5401 cctggacctt ttgacaatcc aagcgaagag gcaatcaagg cagtattaga accagcagaa
     5461 aatgactatt attatttcgt agcagatacg agcactggaa atgtttattt cgctaaaact
     5521 tatgaagaac atatggaatt agtggaaaaa tatgtaaata attcttagaa aaacaggctc
     5581 tagacattga tcatttttag aaaaacattt acatttgaag aaaagcgtgg taatcttttt
     5641 tggactatat tcctcaaaag attacctttt gcggtatttt atcgaaaaaa ggagacgtta
     5701 cacatggtag agaaagttta tccaatgact ctagaaggta aagaaaaatt agaaaaagaa
     5761 ttagaagaac taaaaacagt caaacgcgga gaaatcattg aacgaatcaa aattgcccgc
     5821 ggtttcggag atctttccga aaactctgaa tatgaatcag cgaaagatga acaagcattt
     5881 gttgaaggaa gaatcacaac aattgaaaat atgattcgtt ttgctcaaat catcgataac
     5941 gacggtgtag atgcagatga ggtatcaatt ggtaaaacag ttacattcat cgaactacca
     6001 gatggagaag aagaagagta cacgattgtc ggaagcgctg aagcagatcc gttttctggc
     6061 aaaatttcca atgattctcc tattgcgcaa gcattgattg gcaaacgtaa aaatgatgaa
     6121 gtaactattg ctactccagg tggcgatatg ttagttaaaa tcgtcaaagt agaacaagcg
     6181 tagtctgact gaaagatcta gagagttcat cttactgatg atacactcta gatctttttc
     6241 tctttgtgta ttttagattt caacaaacga tcttacatct aaagtcctat agccaacagt
     6301 taaaaaaata ggtatgatga aatgagaatg tgtcaggagg gagaaagagc gatgaatagt
     6361 tcttggcgtt tttttgtggt agttgaagca ctactgctgt tatttgctgt ttggcaaatc
     6421 gtaaacaata ctggactttt gcttttagtg atattcggta ttttcaatat atatctagct
     6481 atgcgcaaac atcctcgtac taaatttcaa aattttcaat tgatattagg aagtttggtc
     6541 atttttttta gcttagtcaa cagtcctgct ttatggatga tggctgtatt tgccgtttta
     6601 tttattggtc tgaaaggtgt agagatttca gggatagatt taaccaaaaa tgctttttgg
     6661 cgaaagaaac agatcatgat gatccaaaca gagcaattaa aaacacataa taatgagcgg
     6721 aaaagacagc aattattcgg taaccaacgt attggaaacg acgtctatga atgggacgat
     6781 atcaacatcg ccgtcatttc tggtgatact atcatagatt tgggcaatac gcttttgcca
     6841 aaagatgata atattgtgat tgtaagaaaa gggataggca gaacacggat cttagtacct
     6901 ttgggcgtag ccatccgatt agagcatgcg acattagtag gaaatgtctt gtttgaagaa
     6961 gagcaatttt ctttgaaaaa tgaacaaatc aaaatctaca gcagtgatta tgatgaaaac
     7021 cctcgtagat tgaagattat tactaatacc ttgattggag atgtcgaggt gatacgaata
     7081 tgatgggaaa aatatccaga gcgatgctag ctgtttattc ggggattgcg gctttcctta
     7141 ttattctatt ttcacttttc acttattttt atgccagcaa tcaaagtcat tggtggggag
     7201 aattactgcg tgcacgttta ttatatgttc cgcttatctt ccatttgtta gccatttcct
     7261 taggtgtagg attaattgtc tttctattat tatcacttat tcaaaagaca aaatacggga
     7321 aaatcgaaga aaagctgcgt gcactttctt ctggcaatta tgaatccaaa ttgttgcttc
     7381 ttccgatccc aagtgcatcg gacgatttat acatcaaaga tattgataag gaaatcacta
     7441 agataaaaga aaaaatgatt gaagtatcta gtgaattaca aattgtaacg agccgtcccc
     7501 aatatgtaga tggacaaacc aaagaagaaa ttttagaatt agaaagacat cgattagccc
     7561 gtgagctgca tgattcagtt tcgcaacaat tgtttgcagc aatgatgatg atgtcggcat
     7621 tgacggagca agcagaaaaa agcgagacac cagaaatgtt tcgcaagcag ttgaaaatgg
     7681 tagcagagat catcaacgct tcccagtctg agatgcgtgc gctgcttctt catctacgtc
     7741 cagtcaattt agaagagaaa agtttaaagc aaggtatcga gcagttattg aaggaattgc
     7801 aaaataaaat ccagatttcg ctgaaatggg atgtagaaga tgtaaaacta tctagttcca
     7861 ttgaggatca cttgttccga atcgttcaag aattgttatc aaatacatta agacatgcta
     7921 aagccaatga attagaggta tatttgcaca aaatagacaa taatcttttg ttacgtatta
     7981 ttgacgacgg aacagggttt aatatgaatg aaacgaaaac gggaagttat ggattgaaca
     8041 atatcaaaga acgagtagct ggtattggtg gaacagtaaa aatcattagt tttaaaggtc
     8101 aaggtacaag tgtagaaatc aaggtccctt tgatgaagga ggcatagata aggatgataa
     8161 aagttttatt agtagatgac catgaaatgg tgcgcttagg cgtctcttct tatttatcta
     8221 ttcaagaaga cattgaagta attggagaag ctgaaaatgg acgacaaggc tatgagaagg
     8281 cgatgacact tcgaccggac gtcattttaa tggacttagt catggaagaa atggatggta
     8341 tcgaatcaac aaaagcaatc ttaaaagatt ggccagaagc taaaatcatt atcgtaacca
     8401 gttttattga tgacgaaaaa gtttatcctg ccattgaagc aggtgcagca gggtatttgt
     8461 tgaagacctc taccgcacat gaaattgctg atgctataag ggcaacgcaa cgtggcgagc
     8521 gagtattaga accagaagtg acaacaaaaa tgatggaaaa aatgagtcgg cgaaatgagc
     8581 ctgtattaca tgaagaacta acgaatcggg aaaatgaaat tttaatgctg atttctgaag
     8641 gaaaaagtaa tcaggaaata gcggacgaat tgtttattac actgaaaaca gtaaaaacac
     8701 atgtttccaa tatattggct aagctagaag tggaagaccg tacacaagcc gctatctatg
     8761 cattcaaaca tggtttggtg aaataaaaac gatgataaag aggataatca aaagctgaga
     8821 aaataactat tatttttctt ggctttttta caataatgat gcttgctttt gtttttgtaa
     8881 aggctttgtt atactgagaa aagaagatac taaaggagga aaacggtgaa acaaaatttt
     8941 gcaattgtag gtcttggacg atttggcgga agtatctgcc gaacactgat cgaagctggt
     9001 caagaagtac tggctattga tagtaatgaa gatcgggtca atgaatatat gaatatagcc
     9061 actcatgctg ttgtggcaaa tgcacaggat gaaatgacac ttcgatcatt aggcataaga
     9121 aatttcgatc atgtaattgt cgctattgga gaagatattc aagccagtat cttagttact
     9181 ctgatggtaa aggaaatggg cgtaccaaat attttagcaa aagcccaaaa tgagtatcat
     9241 gccagagtac ttgaaaagat cggagctgat cgcgtcgtcc atcccgagcg agacatggga
     9301 ataaggattg cgcataattt agtgtcaaag aatattttag attacctaga gttgtcagat
     9361 aaatattctt tagcagaaat ccgagtctcc aatcctaaat ttttcaacaa aacattagct
     9421 gaattaaatt tcaggcaacg ttttgactta acagtagtcg ccatacgaag agtagatcaa
     9481 acggttatcg cttctcctgc agcagatgaa tatgttcgtg aaaatgataa tctactggtt
     9541 attggagaga caggcgatgt ggatattcta gacgataaga tgaatcaata gaaagaaaag
     9601 agaaagtagg ttgttgggat gaaattaacg gtaacgccaa aagcacaaaa gtggtttgac
     9661 tcagaaattg atctgccaga aacttacgga atacgttttt ttggaaaagt ctacggcaaa
     9721 acagaggttc atgatggttt ttcgattgga atgtcagttg aacagccaga acatcctgta
     9781 aagaaagtgg aaatggatgg gacacttttt tttatcgagg aagcagatga atggttcttt
     9841 aaaggatatg atttacttgt tgattatgat cccaacctgg aggagccaac ctatcacttt
     9901 aaaaaacaat aaaaaaagag agggtgacac aatttttgtc accttctctt ttttcttttg
     9961 aaaatattgt tttcagctat taatatcctg cagacaattt tacttgattg gtttgaagct
    10021 catgggtggc aaagtagctt ttcagattgg ttaaaaaaat agccattaat ttcttttgaa
    10081 aatcaggtgt caaacctgca atgtgggaag taatcagtac attgtccatt ttccaaagag
    10141 gatgatcttg tggaagaggc tcttcctcaa aaacgtctaa tgctgcaaag gaaagttgct
    10201 ggttatttaa agcctgcacc agatcttgtg tcttaacaga agcaccacgg ccaacattga
    10261 tgaatacaga ttttggatca aagtgttcaa acatatgctg atcaaagagc ccagttgttt
    10321 cctccgttag aggtaagata ttgactacga aatctacttc aggaagaact tcctttagtt
    10381 gatttaaaga aaaagtcttt tccattcctt ctgctggatg accggatgta ttgattccat
    10441 agcagttcat gtctaatgct ttgcattttt ttgcaatcat ttttccaata tggccagttc
    10501 caatgattag tatttttttc ccttggatag attggtaatg gaccgatgaa cctaaccatt
    10561 tcatgtcact ctgtgccttt tgtgcttgaa aaagaccacg agaataccca aggatgattc
    10621 ctaagacatg ctccgtaatc gattcactgt ggatgccact accatttgaa agtaaaatat
    10681 gtttctttga aaaagtctca aggggtagct gatcaacacc agctgagata gattggaccc
    10741 atttcaaggt agaagaggct aatagttttt cttggtagtc tgagttccag cccaaactga
    10801 tctctacatt ttgtagatcc tctggttgta attctgtttt aaagatataa ccaggcgcta
    10861 tagtatggat ttcttcgata aattcatcac gaaatggacg atctgcataa atgattcttt
    10921 ctgacatagt taatttcccg cctttcttta ctctaagtgt agcgcataca agaagaactt
    10981 tgaagcgcct tgcttgtttt ttgagaaaga aatatttttc aaataaaaaa ggggctgtga
    11041 caaaaaaatg tcacaacctc taaaagggtc tattgaagta gaaataacga gttgtcttta
    11101 tttcttaatt gatcgatatt tttgcccatc ctttgacagc ttgagcaaaa ataaagattc
    11161 ctgcaaaagc aatgaaggcg ctagtgtcaa aagaaggaag aaagaccatc aagattgttg
    11221 caattatagt aggcaatgaa attgaataga tcaatgtttt taaacaatca agaaaagtag
    11281 cttttgttag tcgaaagcgt gcatagagaa aagcagcaat gttggtaaat agcaaagtga
    11341 tcagcagatt cagaaaacta ggataaatag aaaatataaa tgtcaggact tttatccaaa
    11401 gtggtataga tgcttcactt aaaaaagaac ggagctgctt acctgttaag ttttttaaag
    11461 attcattggt gtagggaagt tctaattggt tattgttcaa caaagcagaa gtcgtgcctg
    11521 tattaggaag agctatgata agtttgtttt ttaacatccc gacactaaca aaattcccca
    11581 tcaaatcagt agagatgtcc tgttctgttc gttttccctc tggatcaaat gtgaagataa
    11641 tggagtttgt ttggtaaatg aatccttctt tttcttcggt ttgaagctgc ccgttttgga
    11701 ttgtaaaatc aggaatgcga gtagcaatct tttgcccatc caattgaatg ttgtttaaga
    11761 cttgaaaaac ttgaaaagag attggcaaag ccataattat actcaaaact aaaagataga
    11821 caatggcttt ccaaaatggg acatttctcg cctcctttag gtctttgaat cgtataaagg
    11881 aactgataat taattgtttt gttgtcataa gtactcctca tctagtagtg tcatcacttg
    11941 caattctagc gaagtatcaa gtgaaataca agtgctttaa ggaaacagct gaatgattgg
    12001 tgaaatatca aaaaaatgtt attcttgtct aaagactatc caatataaat aaaatggagg
    12061 aaggaatagt gcctacacag ccacagagat catcaaaaaa actatttgga gtagtggttt
    12121 tgaatgcggt gatcacttta tcagaattta ttggagggat tatgtcaggg agtttgtctc
    12181 ttgtttcaga tgctttccat aaccttagtg atacattggc aattattttt tcttacgggg
    12241 cacaaaaaat ggcccgaaaa gaagcaaata aaaaacgtac gtatggctac cagcgtttag
    12301 aaatattgag tgctttcatc aactcattca tattgatcat attatccttg tttttaaccg
    12361 ttgaagcatt caagcggttc acttcaccag aaaagataaa tagtcatttg atgctaacag
    12421 tagcagttat tggattgctc gcgaatttgt tctcagtatt attattacga caagaagcag
    12481 atgaaagttt gaatataaaa tctagttatt tgcatttgtt aagtgataca ctgtcttcgg
    12541 taagtgtgat tatcggagca attttgatcc gttttttcga tatctactgg atcgatccag
    12601 ttattacact gatcatttcg atatatatat tgatagaagc gataatggtg atcaaaaaag
    12661 ctgccgctat tttgatacaa agtgcacctg ctatcgacta tgaaaaaatg gaacaagaaa
    12721 ttgaagcaat cgatggggta aaggatgttc atcatgtcca tatttggcag tatagcgaaa
    12781 agataattat tttcgacgga catattgatt ttgaagatca gctactaagc gagattgaaa
    12841 agatatatcc tcgtataatt tctttattaa aattaaaata tggtattaca catgtgacga
    12901 tccaagcaga gacaaaggca aaggatcaaa aaaaattaat ttttttaaat aaagatgaaa
    12961 gttattgaaa tatagagtat gataaataag aatttttaat aaggtaggtt ggctcatgaa
    13021 gcagtatcga cagttaaaag gatatttaga agcaaaagga tattgggaga tactagtcta
    13081 tctctttttt ggtggtttgg ctacgattgt aaattttgtt agttttgctc tcgcacgcca
    13141 atattttgat ttaagtatgg ccttatccaa ttctatttcg tggttttgtt ctgtattgtt
    13201 tgcttttgta acgaacaaac tttgggtatt ccattcaaaa tcaccgaatt ttacacatgc
    13261 acttattgaa tgcggtaagt tcttcttcta ccgtatcctt tcttacggat tggacatggg
    13321 ggcaatggta ttgttgatca atgttatgaa cagcaatgag tatgtggcga aaatcatcac
    13381 tcaaattatt gttatccttg cgaactatat tttcagcaag ttgtttattt ttaaagaaac
    13441 tgaggttttt gaagaagaag taggtcaaag tgaaaaagac gactaggcat aacaattgaa
    13501 gaatttcctt ctctttgtta ctctttgtaa tgtagacatt attaagaaaa cattgaggag
    13561 gaattttttt atgacttaca cattaccaga tctaccttat gcatatgacg cattggaacc
    13621 ttatattgac gaagaaacga tgcatctgca tcatgataag catcacaata cttatgtgac
    13681 gaatttaaat tcagcaattg agaaataccc agaattaggc gaaaaaacaa tagaagaatt
    13741 attatctgat atggacgcta ttccaacaga tatcaagaca gctgtacgta acaatggtgg
    13801 cggacatgct aaccattcat ttttctggga aatcatggca ccaaatgctg gtggcgaacc
    13861 tacaggagaa ataaaagaag cgattaatga agcttttggt gatttttctt cttttaaaga
    13921 agaattcaaa aaagcagccg ctggacgatt tggttctgga tgggcttggc ttgtaatgga
    13981 aaatggaaaa ttagctatta cctctactgc aaatcaagat tctccattga tggaaggaaa
    14041 gacaccaatt ctaggtttgg acgtttggga acatgcttat tatttgaaat ataaaaatgt
    14101 ccgaccagat tatattgcag cattctggaa tgttattaat tgggatgaag taaacaaacg
    14161 tttcgaagca gcaaaataac catttcctcc gtcatatcag tcttaaaaat aatttggaaa
    14221 ataaaagagc gaaagcttgc tagcgttttc taaattgggt ataatgttct tgcaaggtta
    14281 cttgcaagaa cttttttgga ggatatacat ttatggaaca cggaacggtt aaatggttca
    14341 acaatgaaaa aggatttggg tttattacag tagacggcgg agatgacgta tttgttcatt
    14401 tctcagcaat tcaaggagac ggcttcaaga gcctagaaga aggtcaagaa gtagaattca
    14461 cgattgttga aggtgcacgc ggacctcaag ctgctgaagt gactaaatta taataatttg
    14521 ttgaataaag acacgacttc ttagagagtc gtgtcttttt gtctatttat gaagttttta
    14581 gattttttgg ctaagtaaat gcatttgttc acttgacatg tcctaactaa ttatcaagca
    14641 aggaacattt tcttcgttag taatggattt taaagaaatt tcagtttttg gatgttgaat
    14701 aaaagaccat ttgtgaaacc actagtatac atactcatta ccatgtcaat tctattactt
    14761 taaaagaaaa tcgttttact ttgaagagga gcatatctat ccattaaaag atgatggtaa
    14821 tgcaatcact agttcgagtc attttaagag ccatgcagtg agctggaaat aaaacgaata
    14881 gaagatgggt ttaacaaaag gaccagtcat aggaagaaat tgtcgtgaaa tcgaatgata
    14941 atctgaacgg taggcaaaga ctgttaaaaa gatgggaaag gtatgtgcga tcattttact
    15001 gcacgattat ttggaaaata ccttgttgtt cgctttttct ggaaaaaata cataaaaaaa
    15061 gataaaacga ttgcgaactg cgtgtattcg gtctttcgat ctttttcacg gtatggtatg
    15121 atagttaaga attttgagaa attttaaaaa ataataatcg ttacacaaaa atgtttttta
    15181 aagttttctt atgattaaaa agtgaatttg ctgattgaac agttatatga gacaatattt
    15241 tagaaaatgt gaaacagagg tgtattatga agcgatggca aaaagttcta ttaaccttgt
    15301 taggggtatt cgttttgctg attgccggat tatcagcata cggaatcaga tttatgggag
    15361 aagcgagcca aacagtaaac aaaatttcta aaaactctaa tcgaatatcc tccaaacgtt
    15421 ctgagagagt aagcattgat gacaaagaac ctttttcggt tttgctatta ggtttagata
    15481 ccggtggatt aggaagaacg gaacaaggac gttctgatac gatgatggta gtaacagtta
    15541 atccgaaaca aaaaaaatca acgatcatca gtttggaccg agatatttat acgaatatcg
    15601 taggttatgg aacggtagat aaattaaatc atgcctacgc atttggtggt gtcgaaatgg
    15661 ccatggattc aattgagcaa ctgctcgata ttcctattga tcattatgta acgatcaatt
    15721 tggatggcat ggaagatttg atcaatgcgg tcggtggcat caaagtgaat aataaaattg
    15781 actttacttt ggatggtgtc catgtaccag taggtgaaca aacattgaat ggagaaaaag
    15841 gtttagccta ttctcgaatg cgacacgaag atccagaagg cgatatcggt cgacaacgtc
    15901 gtcagcggga agtagtgacg aaaatcgtca ataaagtttt aagtttagat ggcgtaagca
    15961 attatagaaa aattttaaaa gcagttgaga acaatgtgac gacggactta gattgggatg
    16021 acatgcttga tgtagcgacg aactacaccc cggcgtttga aacaatcaaa caagaccagt
    16081 tgcaaggcga aggacaaatg atcaatgata tctactatca aattttagga aaaaatgatc
    16141 ttctttcgat ccaaaatgaa ctgaagaaac aattaaatat aaaaacaagc gatacattac
    16201 ctaatttgaa aaatgagaat gcttcaatga tgttctttga tgattcggaa gatggcgatt
    16261 cgacaaacgg tgatggatcg aatagtgaag ggtacaccga ttattcttcc tattcagaaa
    16321 acacatatga tcagtaccaa gatccgaata cctattatca gcaaacagaa gatacaagtc
    16381 agtactatac accaagtcaa gatactcaaa gttatgatcc ttacgctgga caggaacaaa
    16441 atggttatgg ttatgaccag aataatgagt atggaacaac aagtgggtac tagaaaaaaa
    16501 tagtttggtt aataaagagt gccacctaaa ttagacaaaa aatctaactt aggtggcact
    16561 tttt
//
LOCUS       DAPBBR010000054        16399 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPBBR010000054 DAPBBR010000000
VERSION     DAPBBR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.057"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(296..1024)
                     /locus_tag="RD488_002096"
     CDS             complement(296..1024)
                     /locus_tag="RD488_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDT7658157.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="RD488_002097"
     CDS             complement(1002..2576)
                     /locus_tag="RD488_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7658158.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="RD488_002098"
     CDS             2805..3743
                     /locus_tag="RD488_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7658159.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="RD488_002099"
     CDS             3755..4666
                     /locus_tag="RD488_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7658160.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="RD488_002100"
     CDS             4690..6162
                     /locus_tag="RD488_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7658161.1"
                     /translation="MKKNMQKYLIGGVSVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6214..6825
                     /locus_tag="RD488_002101"
     CDS             6214..6825
                     /locus_tag="RD488_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7658162.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6855..8768
                     /locus_tag="RD488_002102"
     CDS             6855..8768
                     /locus_tag="RD488_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HDT7658163.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8896..11877
                     /locus_tag="RD488_002103"
     CDS             8896..11877
                     /locus_tag="RD488_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HDT7658164.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11874..13535
                     /locus_tag="RD488_002104"
     CDS             11874..13535
                     /locus_tag="RD488_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HDT7658165.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13575..14507
                     /locus_tag="RD488_002105"
     CDS             13575..14507
                     /locus_tag="RD488_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7658166.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(14867..16360)
                     /gene="guaA"
                     /locus_tag="RD488_002106"
     CDS             complement(14867..16360)
                     /gene="guaA"
                     /locus_tag="RD488_002106"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7658167.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         5238 a         2688 c         3303 g         5170 t
ORIGIN      
        1 atttaaataa ctacatccat ctattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt acaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgtttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgacga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttta ctaaatgaaa
     6181 agaatagact aagcagttag tggggggatt caaatgaacg aaaacaaatg gaccaaagga
     6241 tttaattggg tttttcaatt gttattacta aactttactt attttatact aatttgttta
     6301 ggatttggaa ttttaggttt tttccctgct acgatagctt tgattgctgg cgttgtgaat
     6361 cgaaaaaaat atggcttgca agagtctgtg aagttcatga gtaaaatcta taagaaaaat
     6421 tttgttagat ataatctata ttgctggtca gcaactttgt tgttggccgg caatattact
     6481 acgatctggc tttgttggca gcaaagcgca ccattgtttt atttattaag tacattatta
     6541 tcggtaatta cactgttcct agtctttgca atgttgaatt gggtcgtgat caaaagtctt
     6601 gggttgtgga tgatgggaga ccgactgatt gactatttgc ttttcacagc aacgatgttg
     6661 ccaacggtag tcatgcaagg cttggtgctt ggaatttatt tccgaatatt gatgattttg
     6721 cctgtgattt ttctgtttgg cggaacagct gtaacggtaa tattgattag taaattaact
     6781 gaaagagcgt tagcaaagtt gccttgtcag atacaatcgc actaattttt tcacaaaaag
     6841 gagtatttct ttctatgaag ttaactgata aacaagtagc taatatagcc tttatccagc
     6901 aacttgagat tccattgaca caaaaagatg aagaacaaat agacttgatt tttactgaca
     6961 caaaggctaa tgtgcgacaa atcaagatta ctaaaaatga gcagcaacga atctgcttgt
     7021 cttattcaca tgaagacttg ctgtatcgag gattgtttat ctgccttcca cgttttttag
     7081 ctcaaggagg agagatgcca tacattgaag aaacctcgat cattgagacc agttattcat
     7141 tagatgcttc tcgtaatggc gtgatgaata aagagactct aaaaaaattc atttcttact
     7201 tagcgttgat ggggtacaac acattgtata tttacacaga agatacctat gaagtagaag
     7261 accttccata ttttggttac cttcgcggag cgtatacaaa agaagaagtg aatgaaattg
     7321 ttgaatttgc ttctggtttt ggcatagaag tagttccatc gatccagacc cttgctcact
     7381 tgacccaatt tttgaagtgg tatgctcaac aagaactgat ggatgatcaa aatactctac
     7441 tgataggtga agaaaaggtt tatgcggcaa tcgaaaagat gattattgcc tgcaaagaaa
     7501 tgtatcagac agagcgtatt catttgggaa tggatgaagc ctatcaagca ggtctgggac
     7561 gatatttaag cctgtatggg tattgtgatc ggacaacttt aatgattcaa catatggacc
     7621 gtgtgttatc aattgttgat aaatataaga tgaaaccaat gatttggagt gatttcattt
     7681 ataagctatt agatgaaacc ggtaaagata ggtattacaa tcctgatttt aaactcaaag
     7741 cattagcagc taaaggatta ccagcaggat taacctatgt tcattgggac tatggttcag
     7801 atgaagtttc ctcctatgag aaagtaattg ataaccattt gaaattttgt gacattgatc
     7861 attacgtttt agctagtggt gcccatatct gggggagact agccccgaat catgggaaaa
     7921 cagaagcaat tgtttctgca gctgtaaaag cttctaaaaa taaaggtgta cgttctgtga
     7981 tgttaactac ttggggagat gaagggcagg aaacagagca ttggcattcc ttaattgggg
     8041 cattaaaatt agcagattat gtctattctg aagaagagtg gaatgatttt gaggaaatct
     8101 acgatcgttt attaggaaca ggtagttatc aattaatgtc cgaattacga tatttcgatg
     8161 aagtggatac cattacaaat aacaacttac aaatggcttc cgtgagtaaa ctgctacttt
     8221 ggcaagatcc gttagttggt atatatgact ttcatgtagc cgctcataac aaaattgcca
     8281 ctagaacaat tggtacttat tatcatgagt tagctcagaa attagatatg aataaaaatt
     8341 ggaatccaaa acaaccaatt ttaacaacta ttcgtcaacg atatatactt ttagctgaaa
     8401 ttttagcaca aaaggcagaa ctaggcatct atttacaaca ctgctgtctg gtagaagacc
     8461 ttgcaggatt aatggaatta gcgaatcggt gtgaagcact agccaatcga gtaaatgaat
     8521 tggcatctat tcatgaaata atttggtatc aaacatacaa aacctatggt tgggaagtat
     8581 tagaacaacg atatgctgca ttagctcatc gtctgaaaac cgttgcgcgt cgtattaaaa
     8641 atcatcttca ggggcaagat gccctagagg agcttttgga agaacgatta ccgttttgtc
     8701 aatatcaagt gccgcttgaa atttctggct ttaattatcg gcaaagctcg gtgtcaggct
     8761 acaattaacg aaggaatctt cccgttgaac ggaccacttg ctcatctaat gggaaagtgg
     8821 ttcgttttct attcataagt agcttaccac taactctttt attaagaaga gaaaaaaagt
     8881 aggaagtgag aaaatatgtt atcggactat tatcaaaatc tgtcagttat aagtgtcaat
     8941 acagaaccat tacgtaatta ttatattcct tatgcaagta aagaagaagc aaaacaagag
     9001 ttagaaaggg aaaaaacgag ccagtttatc gatctcaatg gtacatggga ttttcagtat
     9061 tatccttctg tccaacagtt accggaaaat ttttttcaag aggcctttac tgaaagttat
     9121 gatagaattt ctgttcctgg agtttggcaa acagagggat ttgacttacc tcagtatatc
     9181 aatgtatctt atccaattcc ttttgatccg ccttatgtac ctaatgatac cccttgtggt
     9241 gtatatcggc gtcagtttca aattgagcaa acagatgcac gcttttactt aaatctagaa
     9301 ggagcagata gtaattgttt tgtttggata aatagaaact ttgtaggcta tgaccaagtg
     9361 agtcatagta catctgaatt tgatgtgacc aagtatttac aggttggggt taatgaaatt
     9421 caaattctag tgatgaagtg gtgtgatggt acctactttg aagatcagga taagtggcga
     9481 atgagcggtc tatttcgtcc agtgtatctt cttcaacgac caactatgca tctgacaagt
     9541 tatcaactac ggacgttgac tgatcctaaa aaaggaagcg gaacattaat ggtttctttt
     9601 caacgattta ctcctattga agtatcgtta cctatttctt acgaattatt ccatcctgat
     9661 ggacgtctca tagcgaaagg ggagtgttac tcggaacaac aaataaattt ggatgttgaa
     9721 gattgccttt tttggacagc agaaacgcct aaattatata cattactttt aacatgtaat
     9781 ggtgaatatt ttaaagaaaa agttggcttt cgagcactga cgatcaagaa tcgtaagtta
     9841 ttgctgaacg gaacacctat taaattatat ggagtcaact atcatgacgt gaatcagcaa
     9901 ggcacgccag tgatgacccg agagcagtta cgtgcagatt tgttattaat gaaaaaatta
     9961 aatgtgaata ctgtacgaac ggcacattac cctaaatcac cagattttta tgaattggcg
    10021 gatgagattg gtctgtatgt aatcaatgaa gcagatttgg agtgtcatgg tgtggttaat
    10081 ctatatgata ctgaagcgaa ttatcaacta attgctaatg atccgacatt cgaaaagccg
    10141 attatggacc gagtgatccg ttctattctt ccttatcaaa atcgaagctc tatcattatg
    10201 tggtctatgg ggaatgaatc tggttatgga gtaaattttg aaaaagctca agctttagca
    10261 cggaaattgg atgattcacg gttgattcat aatgaacgct cgattgaacc agttattgac
    10321 caagtgaatg attttagtaa cttggatgtt attagtcaaa tgtatccccc actggaagat
    10381 gttcatcgtc attgtcaaag aagtgatact gaaaaacctt tttttatgtg tgaatatagc
    10441 cacgctatgg gcaacggtcc tggagatctt aaaacgtact tcgatttgat tcaacagtat
    10501 gattcctttc ttggcggttg tgtctgggag tggactgatc atgcaatcaa tagaggaact
    10561 ttagaaacgc catcttattt atacggtggt gattttggtg aaaaatatca cgacggcaat
    10621 ttttgcgtag atggtttatt gaccccagat cggcaattaa cagtaggtgc attggagtac
    10681 cgtaatattc attcgcctat tcaactgatt gctgtagatg aggagctgca agaagtaacc
    10741 ttgagcaata taactgcttt tacagccggt tcagcattta acctttctct tgaatggtat
    10801 atagatggaa aaaaaacagt ttatgaagta atgaatcctt tcatacttga gcctggcaaa
    10861 agttgttcat tgcccatcac agtacctaca acgattcatg gtgctcatac ggttgctgtt
    10921 tcgctatctg tttataaaaa tgatgagctt tatggacagc aacagctctt tcttaaaaaa
    10981 gaaaaaatga gattgccaag aactgctcat cataatgatg caccacaaat ttcagtaaaa
    11041 ggcacagagc tgataatcaa aggagaatcc tttatttata tatatcaatt agcaaaagct
    11101 gcgttcactt ctgtaaagat caatcaaaag gaacttttgg aacgtcctac tcaattttca
    11161 atttggcgtg caccaacgga taatgatcgt aacttagtaa acaaatggaa agcagctgga
    11221 tatgctgaaa tgtctttaga aatcagaaaa aaagactgga aattcgtaga tgatcatctc
    11281 ctgatcgaaa cgtcttatcg aggagttatt ccaggattac agccaatttt tacaatgcac
    11341 atacagttga aaataaatgg tgcaggcgta atcaaccaaa aagtatcagt ggagaaaaat
    11401 ccgatttttc cagatttccc tcgctttggg atggactggc cgttgaatga tactttttcg
    11461 aaggtttctt attgtggcta tgggccgtat gaaagttatc ctgataagca ctatgctgcg
    11521 atgtttggta tttatgagat ggagattgag gaatttgatc agccatatat caaaccacaa
    11581 gaatatggta accgctggca atgtgattgg gtatcaatca aaaatcatca aggatctacc
    11641 atgacggttt atggaaactc taatttttct gctctgcctt atagtcaagc tcaattaacc
    11701 gaaaagtcac accattatga attaataaaa gaaaatagaa cttggttcaa tttaagttat
    11761 aaacaaaatg gtatcggctc acacagttgc ggtccttatt tagaagatcg tttccgtttt
    11821 atggaagata cttttgactg gaatatagtg attactttca aaggagaaaa tagatgaaag
    11881 aaacaaagat caatcaagtc aaaaaaaaat tatctcgtta tcaagaagtt gtttatcgaa
    11941 accattgctt aaaatggtca aaaaataagc tgaatgttcg ttttaatgga ttattttatc
    12001 gtttcgaaca gttagaagaa gtctggaaac cggtaacgaa tttccaatca tgtcctgtac
    12061 agctcataaa tgatccaaaa gaaacatacg atttatgtat aacacacctt tataaccagc
    12121 atttgaaaaa tgacggattt tatttaaagg ttactaatga caatcaactt acgattgaat
    12181 cagcaaacct tcgagggttt caatatgcta tggaagcctt attagagagt tttttttcgg
    12241 taggagatca attattatta ccggaattga ttctgaaaca tgaaccatca gtgaaaattc
    12301 gaggaatcat tgaagggttt tatggtatcc cctggacaca tgaaatgcgc ctctctcttt
    12361 tttcatatat gaaagataac caattgaata cttttatgta tgcccctaaa gatgatgaat
    12421 tattacgtaa aaaatggcgt gaactctacg atgcgcaaga attagacaaa tttaaggagc
    12481 ttttatctgc tgctgaggct agcaatatcg atttttggta cttaattagt cctggaaatg
    12541 atattgatat tacgtgtgaa gaagacattc aagttcttct gaaaaagtta gaacaactga
    12601 ttgagcttgg cgtatttcaa tttggtctat taatggatga tattgactat caattaaaag
    12661 gtgctgctaa acgccgtttt cgagagccag cattcgctca tgcctattta gtgaatcgag
    12721 tagaggaata tcttagcact cggttgtcca atcatgaatt agtcatttgt cctacagaat
    12781 atgataatcg tcatggttct cgctatttag caacgttaag tcaagaaata ccagaacaat
    12841 taccgttctt ttggactggc ccaagcacgt tagcggcgtc aatttctaca gaagagctgc
    12901 aggaaatggc ttctgtctat caacggccga tgctgatttg ggataatatt ccggtaaatg
    12961 attatttaga ggataaagaa ctattgttca tgagtccata tgagaatcga acaccgaatc
    13021 tttctaagga gagataccag gttacaggag tagtttcgaa tccaatggct caattagaag
    13081 cttcaaagtt tacgatcaat agtatggcta attacttatg gaactgtgag cgctttgatc
    13141 ctttggaaac ttggacgtca gtcgttgaaa aagtagttgg aagtaaacta caaccagctt
    13201 atcttacctt aaccaatgct tttccaaatc attacacaag cagtctgctt tcagatgaag
    13261 aattactgct agccaaagac ccagaatggg tcacaaaaga aatggctgct ttagtccaag
    13321 cagtaaaatg gatccagcaa gaacaacata catctagatt gagaacagaa ttggagcctt
    13381 ggttacaagc aatcacagaa agttggactt tctggcaaga atggcaatta aaaaaagatc
    13441 caaaagaagc agaagaatgg ttggctaaga aaaaaacaca ccgcatagga cgtgatttag
    13501 taactgccca tttagagcaa attatcaaaa gttagatatc ttaaaaaata aaaagcaaga
    13561 aaaaggagaa caaaatggtc aagagattaa ttagtgcaaa ctacagtgat gtcaagaaaa
    13621 tgacgtcaaa agagttgaag caatccatca aagcgagtga aggacgggtg attgtttgtg
    13681 aaacggttgc taatactctt ccacaatctg gagaaattac gaatgcagaa gttgcgtcag
    13741 catttggtgc agatttgatt cttttaaatg gtttcgattg ttatcgtcct gcagtttttg
    13801 gactgccaaa tgtgacgatt gagaaggttt ttgatctaca gcaaacgatt gaaaacccga
    13861 ttcctaaatt aaaagaacta gtcggtcgtc ctgtgggaat taatttagaa cccattgccc
    13921 ctaaaacaaa tatgatgagt gagaaagtag aaatcagcca aggaagagca agctctgttg
    13981 aaacgataca aaaagcagaa gaactaggag tcgattttat ttgctttacc ggtaatccag
    14041 gcactggagt aaccaattta gaaattacta aatccgtaaa aatggcaaaa aagtattttt
    14101 cgggattgat tattgctggg aaaatgcata gcgccggctc agaagagcca gttgtgaata
    14161 aagaggcgat tatttcttat gcggaagcag gcgcagatat tttactagtt ccttcagtag
    14221 ggtctatccc aggcttttta gagcaagacc taattgaagc ggttcggttg gcaaaaaaat
    14281 atgatttgtt aacgatgtct gcaatcggta ctagtcagga aagtgcccga ccagaaacat
    14341 tgcggcaatt agccattatg aataaaagtt gtggtgttga tttacaacat attggagatg
    14401 ctggatacgg gggattggca ccagcagaaa atattttcga aacctcggtt gcaattagag
    14461 gaatgcgaca taccatcaac tgcgttagcc gctcgatcaa tcgctaacaa aattaaataa
    14521 aaaatggtta aattgattat ttaagtggga acatacttga gatatcagct aacttctgtc
    14581 attttaaaaa aagggactgt gacagaagtg aaaatagaca aaaaatatcc gaacaagaga
    14641 ctaggatagc agaaaaacta tcgttttgca acgaggacca actggaacgt aggagcaatt
    14701 ctcttattgt tcggatattt cgcttgttca aggacttatg tctgtagtgc ccttttttgg
    14761 taggaaaaat ggtagggaac catatcattt ttaatgaaaa tcaagcattt caaaagttga
    14821 aaaacgttga tttatcggca ttccccatcc atattatatt tacgtcttat tcccactcca
    14881 ctgttgcagg tggtttgctg gtaatatcat acacgatacg gttaacgtgt gcgacttcat
    14941 ttacgatacg gacactgatt ttttgcaaga cttcccaagg gatgcgggca aagtcagcgg
    15001 tcatgccgtc aatagaagtg acagcacgga tacctacagt gtagtcatac gtacggccat
    15061 ctcccataac cccaacagag cgaatgcctg gtaggacggt gaagtattgc cagatgtcgc
    15121 gatctaaacc ggcattggcg atttcttcgc gcaagatagc gtctgattca cggacgattt
    15181 ctaatttttc ttctgtcaat tcaccaagga cacgaatacc taagcctggt ccagggaatg
    15241 gttggcgcca aacgatgctg tcaggcatgc ctaattgggt acctaattca cgtacttcgt
    15301 ctttgaacaa tgtgttcaat ggctcgatca gcttgaattg catgtcttca ggtaatccac
    15361 ctacattgtg atgtgatttg atggtttggg cagtttcagt tcctgattcg atcacatcgg
    15421 tataaagggt tccttgtgca aggaaagaaa cgccttcttc accggcaagt ttggttgctt
    15481 catcatcgaa gacatataca aattcatttc caatgatttt acgtttttct tctggatcag
    15541 acacgccagc aagttttgat aagaaacgtt ctttggcatc gacttttata atgttcaagc
    15601 caaattttcc gccaagactt tccataactt gttctgcttc acctttacgc aacaatacgt
    15661 gatcaacgaa gatacatgtt aattgatcgc cgatcgcttt ttgtaaaaga acaccaacaa
    15721 cagaggaatc tactccgcct gaaaggccta ataaaacttt tttgtcaccg acttgttcac
    15781 gaatttttgc gatctccatg tcgatgaagt tatccattgt ccagtcacca gtacattggc
    15841 agacatctag tgtaaaatgg cgcaacaagt catttccata ttcggaatgg cgaacttctg
    15901 catggaattg gattccgtac attttgcgtt ctgcattttg gatcgatgcg atggggcaat
    15961 ctttgctggt agcaacgaca tcgaaatcag tcggtgcttg ggtaactagg tcaccatgac
    16021 tcatccaaac ggtttgtttt tcaggagtgt tttggaaaag ggccgcttct gcagaagtga
    16081 tttccaattc tgcttttccg tattcacggt ttttggctgg tttaactttt ccgcctaatt
    16141 tataagtaat caactgcata ccgtaacaga ttcctaaaac tgggatcccc aaatcaaaaa
    16201 tcttttcatc aataccaaag gccttctcat cataaacact gtttggtccg ccagaaagga
    16261 tgattccttt agggttcatt gcctttactt cttctgcggt aatgcggtgg ctcatcaact
    16321 ctgagaaaac accgaactca cgaatacggc gagtgatcag ttggttatac tgactaccgt
    16381 aatcaagtac gataatttt
//
LOCUS       DAPBBR010000055        16075 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPBBR010000055 DAPBBR010000000
VERSION     DAPBBR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.058"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            59..174
                     /gene="rrf"
                     /locus_tag="RD488_002107"
     rRNA            59..174
                     /gene="rrf"
                     /locus_tag="RD488_002107"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(227..697)
                     /locus_tag="RD488_002108"
     CDS             complement(227..697)
                     /locus_tag="RD488_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDT7658168.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(856..1314)
                     /locus_tag="RD488_002109"
     CDS             complement(856..1314)
                     /locus_tag="RD488_002109"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDT7658169.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1485..2630)
                     /locus_tag="RD488_002110"
     CDS             complement(1485..2630)
                     /locus_tag="RD488_002110"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDT7658170.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2643..3560)
                     /locus_tag="RD488_002111"
     CDS             complement(2643..3560)
                     /locus_tag="RD488_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDT7658171.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNHTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3988..4551
                     /gene="efp"
                     /locus_tag="RD488_002112"
     CDS             3988..4551
                     /gene="efp"
                     /locus_tag="RD488_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDT7658172.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4652..4822
                     /locus_tag="RD488_002113"
     CDS             4652..4822
                     /locus_tag="RD488_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658173.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            5037..6296
                     /gene="lysA"
                     /locus_tag="RD488_002114"
     CDS             5037..6296
                     /gene="lysA"
                     /locus_tag="RD488_002114"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDT7658174.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6283..7083
                     /gene="dapF"
                     /locus_tag="RD488_002115"
     CDS             6283..7083
                     /gene="dapF"
                     /locus_tag="RD488_002115"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDT7658175.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            7086..7967
                     /locus_tag="RD488_002116"
     CDS             7086..7967
                     /locus_tag="RD488_002116"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDT7658176.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7964..8680
                     /locus_tag="RD488_002117"
     CDS             7964..8680
                     /locus_tag="RD488_002117"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDT7658177.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8686..9381
                     /gene="dapD"
                     /locus_tag="RD488_002118"
     CDS             8686..9381
                     /gene="dapD"
                     /locus_tag="RD488_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDT7658178.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9397..10398
                     /locus_tag="RD488_002119"
     CDS             9397..10398
                     /locus_tag="RD488_002119"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDT7658179.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10395..11756
                     /locus_tag="RD488_002120"
     CDS             10395..11756
                     /locus_tag="RD488_002120"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDT7658180.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11716..12867
                     /locus_tag="RD488_002121"
     CDS             11716..12867
                     /locus_tag="RD488_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDT7658181.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12842..14011
                     /locus_tag="RD488_002122"
     CDS             12842..14011
                     /locus_tag="RD488_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7658182.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14186..15565
                     /locus_tag="RD488_002123"
     CDS             14186..15565
                     /locus_tag="RD488_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7658183.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15846..16075
                     /locus_tag="RD488_002124"
                     /pseudo
     CDS             15846..16075
                     /locus_tag="RD488_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5258 a         2840 c         3427 g         4550 t
ORIGIN      
        1 tgacttcaaa tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg
       61 tggtggcgat agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct
      121 tagcgccgat tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc
      181 aaaaagatga actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt
      241 caattgcagc ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc
      301 catttctatc aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag
      361 gagcttcatt tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca
      421 attgatgcat agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg
      481 ctgaatctag ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg
      541 tctgataagc ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg
      601 ttgcagtgtt aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc
      661 cgtcttctaa agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta
      721 tataataaaa agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt
      781 tcagacaata aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt
      841 acgttctttt agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc
      901 acgagccaaa gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc
      961 attgcttgca ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc
     1021 taaaatgtct tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc
     1081 cattggagac cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg
     1141 ctcaagtgaa tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac
     1201 gtcgtattta atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata
     1261 aggtgctttg acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa
     1321 gactcctatc tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa
     1381 tttacaaaaa cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct
     1441 gaaatatttt ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg
     1501 tcaaatgcct gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga
     1561 cggatcaagc cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga
     1621 gtcatgacag aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta
     1681 aatagttgga gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa
     1741 atcattccgc taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt
     1801 aatcctggat agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca
     1861 aaagcatttt tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt
     1921 aaccagctat cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga
     1981 tcggctagat ctttatggtt agaagtcact aaaccagcta ctacatcgct gtgtccgcct
     2041 agatatttgg taccgctatg gacaacgata tcagaaccga gatctaaagg tctttgaaaa
     2101 taaggagtag caaatgtatt gtcagcaata actatcaatc catgttgatg agccagagtg
     2161 gcactttttt ctaaatcagt aatctttaga agcggattgc taggtgtttc aagataaagt
     2221 gcttttgtat tgggtttgat ggattgttct attttatcaa gattactcgt atctatgatc
     2281 gtgtactcga gaccattttt agtaagaact ttgtcaaata gacggaatgt tcctccatag
     2341 acatcatctc ctaataagat atgatcgcca gcttgaaaaa gagaaaaaac ggcatgaatc
     2401 ccagaaagac cagaagaaaa agcgaatcct cgaacaccgc cttccaaatc agcaatcagt
     2461 tcttccaatg caaaacgagt aggattacca gatcttgaat attcatattg tttaggctgg
     2521 ccgacgccat cttgccgata agtggatgtt tgataaatag gtacactgac agctcctgtt
     2581 gtgggatctt cactgatgcc tccgtggatc aattttgttt gaatgtgcat gtttctttcc
     2641 tcctataagt aaatgttttt tgataaatag cggtctgctg cgtctggaaa aatcgtaacg
     2701 acacgatgac caggtggtaa acgacgaatt tctcttaatg ctgctgcaaa agccgcacca
     2761 ctcgaacttc caactaatag tccttgttct cgtgctaact gcctagtatg gttaaaccct
     2821 tctacatcag agattgtctc gatctgattg attgaaaggg gagaaagaaa cggcggaatg
     2881 aattctacac cgataccctc aatttcgtga ggggctggat caccaccatt taacacagag
     2941 ccctctggtt ctacaccgat tattcgaatg tcgggatatt tttctttcaa aaaggtagaa
     3001 gttccagcaa aggttccacc actcccaatt cctgctacaa aactatggat attttctttg
     3061 atttcatgaa agatttctgg ccctaacgta tgatagtaag cagcaggatt atctttattt
     3121 tcaaattgaa gaggcagata gctgtttgat atctcctctg caagtttttt acttttgctg
     3181 atggcaccga tgattccttg ctcactagga gaatggatga tctttgctcc caatgctttc
     3241 atcaattgtt gtttttctaa gctaaacttc tctggaacaa caaaaaccgt tcttaatttg
     3301 tatgtgagtg cggccagagc gatcccaatt cctgtatttc cggcagttgg ttcgatgatc
     3361 gtcgtttttt cattgatttt tccttgggca aatccttctt tgatcaaata actgcccaat
     3421 ctatctttga tacttcctcc aggatttaaa tattctagtt ttgcataaat agcagaacct
     3481 ttaggcatag aatagtgctg attgtcaaag cgataaagcg gtgtggaacc aatagcttct
     3541 gtaattgtcg agataatcat atgggcctcc taaaaaaaga taataaaaaa aggagctgac
     3601 tattaaatca gctccttgaa agacatagag aaaaattgag tagataaaaa gataagttac
     3661 ctggtactca ttctatgaag ggcaattaat agacatgaca aatagtatgc tgcttttatg
     3721 caccatacaa cagcaacgat tcaattgttt ttggttgctg actgtcatgt gtatccctcc
     3781 aagtaaaatt tttattaacg atagcatgaa aaaaaataaa agtcaaaggc ttgaaagaaa
     3841 aaaatatttc gatagcatcg tttacccgtg tttatttttc tgacaaatag gcatgagacc
     3901 ttaaaagata gagaatactc tagttttctg gccggttgtc tgatacaata aagttgatta
     3961 tgataaagaa aagaaggagc aaaaataatg atctcagcaa gtgatttaag agccggtatg
     4021 actttcgtac aagacggcaa actgattaaa gttctggatg caagccacca taaacctggt
     4081 aaaggaaata cagttatgcg tatgaaactg aaagatgtcc gttcaggtgc aacatacgac
     4141 acaacgttca gaccagaaga aaaatttgaa aaagcacata tcgacacaaa acctgtacaa
     4201 tatttgtaca cgatggatga tacagctttc ttcatggatt tggaaacata tgagcaatat
     4261 gaaattcctg tagaaacagt agaagaagaa atgaaatata tcctagaaaa catggaagta
     4321 aaaatccaat tcttcggtag cgaagtcatc ggcgttcaat taccaacaac tgtcgtatta
     4381 cgtgttgtgg aaacacaacc ttccatcaaa ggtgcaacag tcactggttc aggtaaacca
     4441 gcgacaatgg aaactggctt agtagtcaat gttcctgact tcatcgaaac agatgaattg
     4501 ttggaaatca atacagcaga aggttcttat gtaaaacgtg cgtcaaaata attcgctaac
     4561 ggattgataa gaatttgaaa acagagcttg acctcttgaa aggcagatca tcggatctgc
     4621 ctttcaagag gttttttgtg gaatcagcaa attgaaaaat aaaaaagtat ttgattttat
     4681 ttatattttg aaagatgaat ggcaaaagct agagaaagaa aaaactgcac ttatttatga
     4741 agaaattgaa atgattcata aaattgaaaa tatccgaact attccgaact atattgaagc
     4801 gaaaatattt tttcatcact aaatagtgtt gaatttatgt ttttatgtat aaatagcttc
     4861 taatagttcg ggtattttgt ttttataacc atttttattc ttatttttaa aaaaatattt
     4921 cgaaatatac tagacaattc agaaaatttt gtttaatatt attccaataa aattcaaatc
     4981 tttatcaaat gaaattccaa taaaaacgga aaaaaagtga aaagaggaat gaaaaaatga
     5041 cagaattgat aattggcgga gtcacagcaa gcacattggc agaaaagtat aagacacctc
     5101 tgtatgtgta tgatgaagaa aagatgagac aaacgatgct gtcattcaag cgaggctttg
     5161 tatcgaaacg ttttgataca aaagtgcttt acgcctctaa agcattccaa acgattgaga
     5221 tgctgcattt agttcgtgaa tatggattcg ggctagatgt tgtcagtggt ggggaaatct
     5281 ataccgcttt gcaagctgat tttcctagag atactatcta cttccatggt aacaacaaga
     5341 cgccagagga actgatctat gcacttgaaa atgatttgtt gcatattgtt gccgataatt
     5401 tgatggaagt tgaattatta gcagaattaa gccaacgcta tttaaaaaaa atctgtatca
     5461 tgcttcggtt gaatgtcgga gtagaagcac atactcatga atatatcgtc actgcgcata
     5521 ttgattcaaa attcggcatg agctatgaaa gtaaagagtg ccaacaagcc cttcagttga
     5581 taaaagaaag cagctatcta gagttagaag gatttcatgc tcatatcggg tcacaaattt
     5641 ttgatgttac tgcttggtta gctgaaatcg acaaattgac gaattactta accgattttg
     5701 accaacctct ttccttgaat cttggcggag ggtttgggat tcgttataca caaaatgatc
     5761 agccgatccc agtcgaagag gcactaaaaa aactgattga atatacggaa gaagctttgg
     5821 aaaaacgaaa actgaccatt cgtcaattac tgatcgaacc gggtagaagt attgttggag
     5881 aagctggtac aacactatac acgattggtt tcatcaaaaa gacaccacat aaaaaatatt
     5941 actttgtaga tggcgggatg acagataata tccgtccagc tctgtatcag gcagaatacg
     6001 attgtgattt agcagcaaaa ctgtcggaag aaaaaacaga gaaagtgacg attgcaggaa
     6061 aaatgtgtga atcaggcgat gtggtaatta aagaagctta tttgccgaaa gcagaatcgg
     6121 gtgatctttt agctgtttat tccacgggag cttatggata ctcgatgagc agcaactaca
     6181 atcgagcgac acgaccagca gttgtttttg tcaataatgg ccaatcaaga ctgattgttc
     6241 gcagacaagc attttctgat ctactaaggg gggaagtttc ctatgatcct tcataaatat
     6301 aatggctgcg gaaatgattt tatcttatta gattacgcag aagacacaga ttatagtcaa
     6361 ttagccgctt ctttatgcac aaaagaaaaa tatgatatag acggattgat cgccgtaaaa
     6421 atcgatccgt tggaaatgat ctattacaac aaagatggca gccgcgcgcc gatgtgcgga
     6481 aatggcattc gctgttttgc tcgatacgta aatgatcaga acatgatgaa tgaacaggaa
     6541 ttcaacgtag agacattagc aggcacaaga aaaattacgg tgttggatcc ctcacctttt
     6601 tattgcagcg tagatatggg agtgccagat gattctccgg aaaaaatcaa agctaatcaa
     6661 acttatccaa taaaaaacca ggaaatagag atcaatggtg aaaaagtaac gatcactagt
     6721 ttatttttag gaacgattca taccgttgtt tttgttgaaa atgcgcgtga ggaagtctgg
     6781 agaaaaagag gtgaactgat ctgtcatcat cctttgttca aagaaaaaac caatgtcaac
     6841 tttgtagaag tagtcaatga acaagaattg atcgtccgta cctatgaaag aggagtaggt
     6901 tggacacttg cttgcggtac aggttgctgt gcctcttatg tggttgctaa ggaaactggg
     6961 aaaatttcag cagatcaggt agttgttcac ttggaacaag gagacttgat gatctctggt
     7021 gaggatgcga tacaaatggc tggcccagca gttcatgaat ggacaagaat attggaggaa
     7081 tgaagatgat aaaaggttcg atcgtggcgc tgatcacgcc gatgaatgaa gagggatcag
     7141 tagattatgc tggtttggaa aaattgatcc aattccattt agatgaacaa acagatggat
     7201 tattagtttt aggtacaaca ggagaatctt ctacgctcac acaatctgag gaggagcaga
     7261 tccttcaact gacagtaaag aaagtggctg gccgtgtgcc ggtgattgca ggagctggaa
     7321 cgaataatac gaaagaaacg attgaaaaag cgaagcattt tgcttctttg ggggcagacg
     7381 cacttttggt catcacccct tactacaaca aaacaagtga tgcaggacta gctgctcatt
     7441 ttacagcaat tgcagaagcc tcaccgattc cgcttatttt gtataatgtt ccttctagaa
     7501 caggcatgtc gattccaatc catgtattag taaatttagc agaacatcct aatatcattg
     7561 gtttgaaaga agcctcagga gatatggctt atgtgatgga tgccgctcgg ttgattggag
     7621 aagaattctt cctttacagt ggaaatgatg atttgatcct accagtaatg agtgtaggag
     7681 gaagcggtgt aataagtgta tgggcgaata tccaacctaa aatagtccat gaattagtaa
     7741 aagatacgca ggacggaaga tggcagcaag caaaagaaaa gcaattaaat gcacttgaac
     7801 tgatccatgc cttgttcagt gagaccaatc ctattcctgt caaagcagcc atgtcattat
     7861 tagacttacc ttccggacct ctacgcctgc ctttagtttc tctttcaaaa gagaaaaaga
     7921 aacaattagc tcagcttttg ttaaaagaaa ggacggttga aaaatgaaaa tcggactgat
     7981 tggcagtgga cagatgggaa atagagtcga agaagttgca caagaaagag gagatacggt
     8041 ccttctttta cggacggcac ctaaagaagc aactacgctt gcttttacgg aactgccaga
     8101 actgcttatt gatttttctc atccagataa tttagagaaa atcctttcgt atagcttatc
     8161 atatcaactt ccgttagtca ttggcacgac aggttataca caatcacagt tccaagaaat
     8221 aaaagaacat gccaaacatg tacctgtgat gtatagtgct aatttttcgt tcggcatcat
     8281 ggtgatgaat caactaatca agcaagcagc tgcaatgttg caaggctggc agatcgaact
     8341 gattgaaaaa catcatagtc gtaaaaaaga tgcaccatct ggtactgcaa atatgctgct
     8401 tcaaacaatc caagaagtgc aaaagctgca gcccgtatac aactggcaag ggaaaaaaag
     8461 agaagaaaac caaattggtg tacacagtat tcgtgcaggt tctttacctg gtgaacatga
     8521 tgtattgttt gctgctactg atgaaatatt tacgatcaaa catgaatctt tttctaatcg
     8581 aatctttgct gcaggcgcag tagaagcagc ggactggttg aaagatcagt caccaggtta
     8641 ttacaaatta gaagatttat taatggacaa aggggtgtaa aaaacgtgga agctcaagaa
     8701 atcatccgct acattcaaac ggcatctaaa aagacgcctg tgaaagtcta tctgaatgta
     8761 accgagccaa tcgaatttaa agaaagtaaa gtttttggtg aaggaagcag cttcgttgtt
     8821 tttggtgact atgagacgat tgctccggtt ttagaagctg aatcagaaaa aatcattgaa
     8881 atcgaaatcg aaactgctgc aagatacagc gcagttcctt tgctagatat taaaaaaatt
     8941 aatgctcgta tcgaaccagg tgctattatc agagatcaag tgtcaatcgg caacaatgcc
     9001 gtgatcatga tgggagcgat tatcaatatt ggtgcagtaa tcggtgaaaa cacgatgatt
     9061 gatatgggtg ctgtcttagg tggacgagcg acagtgggca aaaactgcca tattggtgca
     9121 ggagctgtct tagcaggtgt gatcgaacca gcatcggcca aaccggttat cgtagaagac
     9181 ggcgtactgg taggtgcgaa tgcagtgatt gttgaaggtg tccatatcgg aaaagatgca
     9241 gtcgtggcag caggagcagt ggttttagaa gatgtggcag cagaaactgt tgtcggtgga
     9301 atacctgcac gtgtattaaa aataagtgat gatcagacaa aagaaaatac agcattgatt
     9361 gctgcgttac gcgaattata gaggagatgg agaaaaatgc gcgaaataga tacctgtatt
     9421 gtgggggcaa ccggattagt cggccaaacg atgctcaaag tgttagaaga atatgatttt
     9481 ccagtaggac gattgaaatt attagcttca aaacgttcag ccggtaaagt ttgtgtattc
     9541 aagaaaaaga aacacactgt acaggaattg acagaaactt catttgaagg atatgattta
     9601 gcgctatttt ctgcaggtgc ttctgtatcc aaagagtttg cgccaatcgc acgaagtcag
     9661 ggactatttg tcatagataa ttcctcagca tggcgggaag attcggatat tccattaatc
     9721 gttccagagg taaatctgga agactataca ttgaatcggc tgattgcaaa tccaaattgt
     9781 tcaaccattc aagcggtact tccgcttaaa gctttacaag aagcctttgg tatccagcga
     9841 gtcaattatt cgacctatca agcagtttct ggttccgggc aaaaaggcat tgaagatctt
     9901 catcgtacgc aaaatgacga ggaaccagtt ttgtatcctt ataatattag ccaaacggtg
     9961 attccggaaa tcgatcagcc tttggaaaat gggtatacaa aagaagaaca gaaaatgata
    10021 aatgagaccc gtaagattct gcatcagcct gctttgccag tatcagcaac ctgcgtacgt
    10081 gtgccaatcg aaaatggaca tggagtctct gtggcagttc aactgcaaaa agagtttacg
    10141 acggaagaaa ttagagagtg tctcagccag tttccaggga ttcaattaga agatgatcta
    10201 gcagcacata aatatccgac gagcattctt gctagaggaa cagatatggt ttatgttggg
    10261 aggatcagaa aagacacttc tttagagaac ggattgttgt tctatacgac tgccgataac
    10321 atacgcaaag gagccgctgc gaatgccgta cagattgctg cagctttaat gcagaaaata
    10381 gcggaggtgg caagatgagt aatacgctga aagtagcgaa attcggcgga acatcgatgt
    10441 ctcatgaaga gcaattcaaa aaagtccgta caattgttct ttcagatccc aatcgccaag
    10501 tgatcgttgt ttctgcttta ggcaaacgta cgtcagatga tgacaaagta acagacttac
    10561 tttatttgat ttatgcttac cttcagcatc atgttgattg gacacccctt tggaaaagga
    10621 tttgtgatcg tttcattcaa gtaagagatg ttcttgccct gcagttacct attgaagatg
    10681 aactagcacg catacagaaa caactggaag acgaaaagat aactgaagat tatttagtaa
    10741 gtagaggtga atatctgact gctcaactga tggctgagta tcttggttac cagtttattg
    10801 acgcaaaaga cctgattttc tttgactatg atgggaaaat cgatcaggaa aaaacagcac
    10861 aggaaatcac aaaagcattt aaaagatatc cgaaaatggt tgttccaggg ttttacgggg
    10921 cgaaccctgc aggaaaagaa aaattattgg gccgtggggg aagcgacatt accggcgcga
    10981 tactggcgaa gatgttgcaa gcggaaagtt atgagaattg gacggatgtt tcaggaatca
    11041 tgatggctga tccgcgaatc atcgatcatc ctaaaatcat cgaggaaatc tcttttagag
    11101 aactgagaga gatggcttat atgggggcta acgttcttca tgaagcagct gttttcccag
    11161 ttcaagaggc tgatatcccc atccaaataa aaaataccaa tgatcctttc gctcaaggga
    11221 caaaaatatc gaatcacgaa atagaaaagg aaaatggact gacaggaata gctggacgca
    11281 aggattttct ttccatcact ttattcaaac gtcatatgtc cgatgaaatc gggtttatct
    11341 ggaaagcaat gagcattttt gctaaacatg agatatcaat cgaacatatt ccttcaggga
    11401 tcgacaatat cggagtgatc gtctcagcag aagcgattgc cgataagtta tttctcatca
    11461 cgaaagaatt aaaagaaaca cttggcgtgg aagaaatcgt cgtgatcgaa gacttagctt
    11521 tgatctctgt cgttgggggt ccgcataaag aattgattgg attatctggg aaagtgttat
    11581 cgatattgaa caaattagaa attcgcacat cgatcttatc acaaggagca caggagttga
    11641 atctgatcat cggtgtaccg aataatcaat atgaaacagt agtgaagggt atctatgaag
    11701 ggatggtgaa tacggatgct gaaagaatat cgaatggcac tccatcaaat tcctgaaatc
    11761 gggtttcatg aattcaagac aaaaaaatat ttatatgaac aagtaaaaaa cagcgaggcc
    11821 gttatccatg aaatcggcga aacaggacta ctcctttatt ttgataatca gcaagaagaa
    11881 acgattgctt ttcgaacaga tatcgatgca ctgccagtca aagaagaaac gaatctctct
    11941 tttgcttcta agcatgaagg ttatatgcat gcatgtggtc atgacggaca tatggcgatg
    12001 cttttagggt tgactgactt tataactaaa cacattgagg atcttattta taatgtagta
    12061 ctgatctatc agccatcaga agaaatttcc ggtggcgcac aaagcgttat tcagtcagga
    12121 ttgttggata aatatgaagt acaagcaata tttggctttc atctatggcc tggactagct
    12181 aagggagaag ttttctctcg accaggacct ttgatggcac aaagcagtga aacagacatt
    12241 atcattaaag gccagtctgc acatattgct tctagtgaaa aaggaatcga tagtctggag
    12301 gcagctgtac gatttttgaa gaatgtttat gattttgacc ggcaattacc ggcagagtgg
    12361 aatcatctaa tgaaatttgg ccaaatccaa ggtggaacga tccgaaatgt tttagctgga
    12421 gaagttattg tatccggaag tatccgttct tacagttcag atatgcaaaa ttatttgaag
    12481 aggggattag accatttagc agaacagttt cactctacag ctactatttc ttttcgctat
    12541 aatgacggct atccagctgt aatcaaccat agaggcttat atgcagcact gttagattca
    12601 aacaaactac atgaattaga tgctccagtt cttcaagccg aagattttgg catatatacg
    12661 caacaatatc catgtgtatt tttcttttta ggtgtcggtg atacccctgc tttacatgat
    12721 ccgacgttcg attttgatat ggatgtttta gaaaatggtg tagaatggta caaaacgatt
    12781 ctttttacag aaaatcttct tgtaaaaatc gatagcagtt caaaagagga gcgagtaaat
    12841 aatgatgaat ttatccaatc gatttagtcc taggctttct agaatagaag tatcaaaaat
    12901 acgacaattc gatcagcaaa tatcgtcgat accagatgtg atcaaactca ccctgggaga
    12961 accggatttt ccaactcctg aacatgtcaa gcaagcagga atagcagcga ttgaagaaga
    13021 cttttctcac tataccggaa tgagaggatt agaggaactg cgggaagcgg cttgtatatt
    13081 tcagcaacag cgttatggat taacttatga tccgcaaacg gaagttttga cgacagttgg
    13141 tgcaacggaa gcgattgcct ctgcgttgtt atctgttttg gaagaaggag acaaggttct
    13201 tattccagcg cctgcttatt caggatatca gccattagtg gaactagctg gtgctgaatt
    13261 gatcccgata gatacttctg acacagggtt tgtctgtcag ccggaacaat ttgaacgagc
    13321 atttgaacaa tatggatcag ctgtcaaagc agtcatttta aactatccta acaatcctac
    13381 tgggacgaca ttgtctgcaa aacaattgaa agcaatcgct gaggttttaa aaaaatatcc
    13441 ggtatttgtt ataagtgatg aagtatatgc tgaattgact tatagtggaa cgcatatgtc
    13501 catagctact tatcttccag aacaaacaat cgtgataagc gggttatcca agtcacatgc
    13561 gatgactggt tggcgagtgg gctttatttt tgctcaaaaa gcccttattg acgaactaat
    13621 taaagtccat caatatctgg tgactgccgc tacaacgatg tcgcaaaaag ctgcggctga
    13681 agcgctaata aatggggtga aagatagcga gaatatgaaa gagcaatatc aaacacgaag
    13741 agactatctg gtccagcaat tggcgccttt aggatttgaa gtgacccagc caaacggtgc
    13801 attttacttg ttttgcaaac tcccagctgc cattcaaact gactcttggc agttttgtgt
    13861 agaattagcg gaacaggcaa aagttgcgtg tatcccagga attgcatttg gcccagaagg
    13921 agaaggttat atccggattt cttatgctag cagcatggaa aaattacatg aggcctgcaa
    13981 acggatcaaa gactttttaa cagaacagtg attcatagat tttatcaaaa aaacaatcgt
    14041 taattttgcg gtatattctg caaggagacg attgtttttt aaatttagtt caaatgaacg
    14101 cgtttctttt gattcataac taatgtaatg ttaagtttaa attgtttaga atgattttaa
    14161 aagaatattc aaggaggttt catcaatgga aaaaatcaaa gttgtcattg taggtgcatc
    14221 tcatggaggg catcaatcga tcttggaact attgacacga tacggtgaaa atgtagatat
    14281 cacgctattt gaagcaggag actatatttc cttcatgtca tgtggtatgg agctgtattt
    14341 agaagacaag gtaacagatg taaatgatgt acgtaatttc agaccagaaa actttccgca
    14401 atccaatgtt catattttaa ataatcacga agtaaaaacg atcgatgccg ataaaaaaac
    14461 agtaacggtt actagcgcat cagataacga aacaaaagaa tatccttatg acaaattgat
    14521 tttgagttct ggtgtcaaac caaacaatct gccagtacca ggagcagatc tagaaaatgt
    14581 ctacttgatg cgtggataca attgggcaac caaaatcaaa gaaaaattaa atgatccggc
    14641 tattaaaaaa atcgctgtcg taggtgcggg ttacattggg atcgaagcag cagaagcaag
    14701 ccgaaaagct gggaaagaag tcgtattgct tgatgtgatc gatagacctt taggcactta
    14761 tttagatgct gagatgacag atattttaga acaacaccta aatgaaaacg gtattgaagt
    14821 tttgacaaat gcaaaaatcg aagcttttac tggtaacgga aaagttgagg caatcaaaac
    14881 aagtgaaaaa gaaatcccag cagatctagt cattcaagct gccggtgtga aggcaaatac
    14941 agaatggtta aaagggatcg tcgacttaga tgaacgtggc tggatccaaa caaatgaata
    15001 cttgcaaacg aatcttccag atgtgtatgc agtaggagat gctacacttg cttattctat
    15061 cccagcacgc aaaaaaatgc cgatcgcttt agcgactgtt gcacgtagag aagcacgtta
    15121 tgtagtaaaa catctttttg aagaagtacc aaacaaaccg ttcggcggag tcgtaggttc
    15181 ctctgcatta agtgtctttg actatcattt tgcagcaagc ggattgaata gctttacagc
    15241 agcaaaagca ggagtagatg tacgagtgtc ttattatgaa gatacgttac gaccaaaata
    15301 tgtaccagaa gaacaaggaa atccaaaagt gtccatccaa ttattctcgg atccaatgac
    15361 ccatcaattg ctaggaggag cagtattatc tacctatgat gttacaggtc aaggaaatgt
    15421 attggcacta gcgatccaaa acaaactgac tttagaagaa ctagcagaag ctgacttctt
    15481 cttccagcca ggctttgacc gacaatggag catgttgaat ctagccgctc aacaagcgtt
    15541 aggagaagaa ccatttgtag aataagaaaa cgaaatattt gaaaagaggt tgtgaaaaag
    15601 ctgccttgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg tttttaactt
    15661 ggctggactt attaccgcag atgcaagctt ttgaacaccg tttattttca aaaaagggac
    15721 tgtgacacga tttgtgtacc gacccccaaa agttagacca aaaaatctaa cttttggagg
    15781 tcggtatttt ttatggttaa atatactttt gaacttaaat taaagatcgt tcatgattat
    15841 ttggatggca aaggcgattg gaccgtaaaa atccagatca agagattgaa gcggaaatgc
    15901 ttaaaattcg ggagaagcac aaggattatg gctgtttacg gatgaccaat gaactaagaa
    15961 accgcggttt ctctatcaat aaaaagaaag ttcagcgctt gatcaagaag ctaggaataa
    16021 aagtaacggc atacacgcgt aaatcacgtc gctacaattc ttatcgagga aaagt
//
LOCUS       DAPBBR010000056        15983 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPBBR010000056 DAPBBR010000000
VERSION     DAPBBR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.059"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(189..1556)
                     /gene="nhaC"
                     /locus_tag="RD488_002125"
     CDS             complement(189..1556)
                     /gene="nhaC"
                     /locus_tag="RD488_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7658184.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1665..3086)
                     /locus_tag="RD488_002126"
     CDS             complement(1665..3086)
                     /locus_tag="RD488_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7658185.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3329..5206)
                     /gene="tdc"
                     /locus_tag="RD488_002127"
     CDS             complement(3329..5206)
                     /gene="tdc"
                     /locus_tag="RD488_002127"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7658186.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5497..6753)
                     /locus_tag="RD488_002128"
     CDS             complement(5497..6753)
                     /locus_tag="RD488_002128"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDT7658187.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(6865..7070)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7333..8634
                     /locus_tag="RD488_002129"
     CDS             7333..8634
                     /locus_tag="RD488_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7658188.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8703..9302)
                     /locus_tag="RD488_002130"
     CDS             complement(8703..9302)
                     /locus_tag="RD488_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7658189.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9556..10437
                     /locus_tag="RD488_002131"
     CDS             9556..10437
                     /locus_tag="RD488_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658190.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10450..12060
                     /locus_tag="RD488_002132"
     CDS             10450..12060
                     /locus_tag="RD488_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDT7658191.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12137..12796)
                     /locus_tag="RD488_002133"
     CDS             complement(12137..12796)
                     /locus_tag="RD488_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7658192.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(13079..13744)
                     /locus_tag="RD488_002134"
     CDS             complement(13079..13744)
                     /locus_tag="RD488_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HDT7658193.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13891..14496)
                     /gene="dhaL"
                     /locus_tag="RD488_002135"
     CDS             complement(13891..14496)
                     /gene="dhaL"
                     /locus_tag="RD488_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDT7658194.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14524..15534)
                     /gene="dhaK"
                     /locus_tag="RD488_002136"
     CDS             complement(14524..15534)
                     /gene="dhaK"
                     /locus_tag="RD488_002136"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDT7658195.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(15509..15955)
                     /gene="dhaM"
                     /locus_tag="RD488_002137"
     CDS             complement(15509..15955)
                     /gene="dhaM"
                     /locus_tag="RD488_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDT7658196.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
BASE COUNT         4587 a         3338 c         2903 g         5155 t
ORIGIN      
        1 aaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
       61 cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttaaaaagc
      121 aattttcttg agtttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt
      181 tccttccttc aattttttac acgtcgacga ttcaataaaa aaccgcctaa tattgtaaag
      241 acaggtgcaa gaatcgagaa aaaggcgaat ggcaagtaat gcaacgcgct aactttcatc
      301 gttcccataa tgaatgtgcc gctgactccc cacggtacga gagaattgac ggtcgcacct
      361 gaatccgcta gtgttcgtgt caaataggtt tttgataagc caacgtcatc aaaagaacgc
      421 ttgaatgttt ctcctggaag aatgatggac agatactgtt ctccaacgat cagattgatt
      481 ccgatacagc tcaaggcagt aaacccgact aaacgagaag gtcggtccat cttttctttt
      541 aattcttgaa cgatggtatc aacgatcaga tatttgatca gtaacccacc taatgccaat
      601 gcaagtaaaa tcaaactagc agaacctaac atactcatga tcccgcctcg agaaagcagt
      661 tcatctagct ttggatcagg tgtatttgcg acataaccat tcatcaagat gtctgctgct
      721 tttccgaccg tcaaactttt ctcatggata aaagaaagaa cgagagcagc tgtcgatccc
      781 gctagtaatg tagggatagc cggaattttt ttgattgccc ccccaaataa aataactagt
      841 ggaatcaatg tccaaggaga gatccaaaag ctcgctttca tgttttggat catttcattg
      901 atactagcta gatcggctga atgactgtta tgtcctaata tcgtataaaa aatcaacgaa
      961 aggacgaatg ctgggaaatc cgtataacgc ataccagcga tatgttcgaa tagattaact
     1021 cctccaatac ccgctgccaa gttggtcgta tctgataaag gcgagcagtt attccctaaa
     1081 aaggcaccgg aaacgactgc gcctgtagtc attgcatcat tgaatccaag taaatgaccg
     1141 atccccaaaa aagcaattcc aatcgtcgaa atcgttgtaa atgaactgcc gacagtcact
     1201 ccgacaattg cacaaacaag aaatgctgtc ggtaaaaaga aacgcacaga aacaagttta
     1261 aatccataaa ccataatcgt agggatggtt ccagataaaa tccatgaagc aactaagaca
     1321 ccaatcaaaa gaaaaatcag gattggaatg atccctggag tgattccttt gatgatcccg
     1381 tcatggatct catcccatgt gaacttttta aatctgccat aaaacaacaa acacatgaaa
     1441 gctgcaagga tcgggatatg tggcgagagc tggaatccga tgatcagtac tcctaggagt
     1501 gccaacaaca cgatcaatac agcgatactt tcttttaaag aaatattttt attcatcgtc
     1561 gatctcctat ttcaaatgaa aaggccctgc catgaaaaaa ctattcactt ggcaggacct
     1621 cctactaaat cagcgacaaa acgtcggctg aaagacttat ttttttattt ttcttctaaa
     1681 cttttttcta cctcaatccc ccaagaatct ttcttgaagt gattgatgat caatggaata
     1741 acgaacatga ccactgtgat agctgctact aataatgcat cactcaatgt cgctgtacct
     1801 aatgtagcaa atacgacaac gatgatagag aagatcagca tgcagctgac tacccaagct
     1861 aatccgtttc cgtttttacc aattcggtaa ggacgttcga attctggatg tttcttacgc
     1921 attttaagca atgaaacagc aatcaaaatg tacacgatac aataaataac agttgtagca
     1981 tttgtaagtg tcaagaatac agcacttacg tcatccatta caccataaag caaagcaaat
     2041 aatgaaataa cgattgattg tgttagaacg acatttctag atacgccgta tttgttttct
     2101 ttatggaatc cgaattttgg tggaaggaat ccttcacgag ctacttggat gattgttttt
     2161 gatggtccag taacccaagc tgataattgt aaaagcacac caataaatac catgaagctg
     2221 aagatatttc cgatcacttc tggtaagcct aggatttgac agtcaatcaa gataggctgc
     2281 gtgatatttg ctaattccat ttttccatct ggtacgacat ttgctacaag catcgcattg
     2341 atgacattca ataaaactaa tccgatcaaa gcgataaata cgccttttgt ataatttttt
     2401 gttgcgtctt tcaaacgagg catgtaaaca gaactcattt cgatcccaac aaaaataaat
     2461 gtgataccag ctaagtattt caatgaatca atatgttcca agtcagggaa agcttttgac
     2521 catgaaaagt cacctagata gccgtttgag actagtccga ctttgaaggc tgccaaaaca
     2581 cctaaaacga acatgatgac tactgggata tataccccta gccatacacc gatgttcccg
     2641 ccgacttttg ccatatcgaa tttcaagttc aagatcgtga tgatccagta gataactaaa
     2701 atacaaccta aaacgaacca gtgattattg ccaagttcta cattaccaaa tgtgtttcct
     2761 aacaatggtc ctaaagtaga agcgaccatt accatacctg ggaacatttg cacccataat
     2821 agccatgcaa cgacaaatcc ccatttgctg cccagtgctg tttttaccca taactgagga
     2881 ccgccttctt gaggaagcat cgtggaaagc tcaccggaaa ccattgatat cggaccggca
     2941 aaaaacaaaa ctgcaaaaat tgaataaaaa atcaatgtcc aaccgactgc ggctaacgta
     3001 ggaatactcc gaaccgttgc acacagtgcc attgtcagac cgataaaggt cccaagaccc
     3061 attttactta cttcagattt actcaccgtt gacactctcc ttgatttttt ggataaaata
     3121 acggtgtctt tgaagtagtt tcagcaataa acgaaacaat tcagcgaata tttgagggga
     3181 ttctttgagt ttattgcttg aagggtttct tcaaagacaa cctcaaaaca aagggatcga
     3241 agagcttagg tctccccttg ctcttcagat ccaaacatgc gtcagaaaca gttagtattc
     3301 aagctgtttt ctaacatgat taccttgctt attttgcttc gcttgccaat aattggtctg
     3361 cgtagatttt ttccaatttt tcttgaagag ctgctttgat tttttcagca tattcttcaa
     3421 agtgttcttc tttgttcatg tatggtgtca ttacgctggc acgcaataca gttacttttc
     3481 cggcacggtt ccattcttca tctgagaatc ctagttggtt cacaaattgt aatgggctgt
     3541 tgccatagtc tgggatagca aagtcagtat gtgaagttaa gaactcatta ccgtaaatgc
     3601 ttcctttcac gtatgaagaa taatcatata cgtcatggtt caatttattc attgcaacta
     3661 agtcatcgtt gcctttttct ttgaatacat agtctaccat attgaaatct ggataagtta
     3721 atggatgaac ttcgatttct ttgtctccta ctttaaatga caagtcattc aagaagttgt
     3781 agaaacgatg tgcaccttcg attgatgcac ccattaattt accatatcct gtgacattca
     3841 aaggtaagac atggtgtgct gcccaaacgc tggctgctgt tgcccctgct tttgaacctt
     3901 ccaagatata agccccaagt aatgctggga tatctgcgcc tttttcaaat acatatgtcg
     3961 caaagtaaga gataacgtct ctcatgcgga tatctttgat gacgatacca ccggcagaat
     4021 atggaacata gcccatttta tgtgggtcaa tcgttacaga ttctgcttct tcgattgctt
     4081 tatacgcact gtgtacttct tctaagatat aatctttgtt ttctgtaaag acattgtatt
     4141 tgtaatgaac atcttttaaa tcttcaaatg gaatgaagtt gttgtcttcg tctaagaaaa
     4201 tcgcacggcc gtatccgcca taagcagcat ctacgtgtaa gtagaagtaa ataccgtctt
     4261 tttctaatac gcgacgcaat gcaacgattt tatcgatacc gtcgattgct ccttcttctg
     4321 ttgatcctac aacaccgact acacctagga ttggtgtttt ttcagctgct agaccacgaa
     4381 cgattttttc aagttcgttg atgtccatgc gatagttgtg gtcaactggc actggaatca
     4441 cttggtctaa accgataccg atgatgtcgg cagcttttag ccatgaatag tgtttagttt
     4501 gtggaaccaa ccattttcct aatttttcta aatgttttcc gctacgtgct gagtgagctt
     4561 tgatttcgtc gattttttct gggacgctgt ctaacagatt catgatttct tctgttgaca
     4621 agttcattaa ttcccaatcg ctttttccag caactagttc aggtgtcact tctttcattg
     4681 caagcggcaa tgatttgatg ttgcgggcat accaaagtcc ttctaagttt gctaaagaac
     4741 catcagcaac gatgtggccc cagccatctt tatagctcat taattttgca aattccattc
     4801 ctacttcttc ttccatttgg cttgttgcag gagaagattc ataggcaacg ttattaccat
     4861 tccatagcat agcaaaattg tacgctagta aagatggcat caatgtttca gagttcatat
     4921 gaccccagta acgtccggca ttatgccaag gaacggaatg ggtacgcatc cgcgctgaaa
     4981 tttctgatag aacatccttt gttttattca cagtgtgttc aaaactagca ctgctttttt
     5041 cttctggcgt aataataggc atgtcttgag gcatgtagtt ttgacgccag cctaaatgtt
     5101 catccaccaa ttcattcaac aaagctttat agatttggcc gttctcagct ttgtccccaa
     5161 tgaatagggc atttaggttt agatctttcg acaatgattc actcatagtg aaaccctcct
     5221 aaaaaaatat ttaaattttg tcgagcccta cattacacct gttcttctat tctgtaaact
     5281 aagttttggc ctgattttta atcatatttt aatatgtatc aattatccga attgttcaca
     5341 cttttgaaat aattaaaaaa aacgagggaa tttacaaatg taaactccct cgcaaagatt
     5401 gtattaacga caaccagcgt tctattttag gatgggtttc aaaattggaa tgttgtaata
     5461 gtatttccct ttttcaaggt aaaaacttac taaattctaa tcaattactt tggccaaaaa
     5521 gtaatttttc ttaccttttc gaataaccac aaacttacca tcgaattcat cggatggatt
     5581 tatgacaaaa tttaaatcgg taacgcggtc accgttaata cttatagctc cgtttgaaac
     5641 atcttcacgt gcttgacgtt tagatggttc aatttttgtg gaaacaagca gttccacgat
     5701 attttcaggt gtgcttgaaa tttcaacgtt cggcatttta ccgaatcctt gcgcgatttc
     5761 ttccgcattt agttctttaa tatttccaga gaacaatgct tgcgttattt tttgcgcttc
     5821 tttcaagtct tcttcactat gcacaaatct tgtaacttct tctgccaaac ggcgttgtgc
     5881 ttcacgtttc tcaggttctg tctctacttt tttcgctaag tcttcgattt cttcttgaga
     5941 caagaaagta aagaatttca agtatttcac tacatcgcga tcatcttgat tcaaccagaa
     6001 ttggtagaac tcaaatggtg aagttttctt cggatcaagc caaacggcac cgcctgcagt
     6061 ttttccgaat ttcgttccgt cagccttcag catcaatggg atcgttaaac cgaacgcttc
     6121 tgcttctggt ccttctaatt ttcggattag gtctaatcca gctgtgatat ttccccattg
     6181 gtctgctcca ccgatttgca attgcacatc gtatgtttta tgcagatgca aaaagtcgat
     6241 agattgcagg atttggtaag taaactctgt aaatgagatt cctacttcca aacggctggc
     6301 aacgatatct tttgctaaca tcgtgttgat gttgaagttt ttaccgtagt ctctcaaaaa
     6361 ttcaagtaaa gagatttttg acaaccagtc gtagttgttc acaaatgtga tatttgcatc
     6421 tttaccaaac aattttctca tttgattgga aagtgcgtcc acgttatgtt gcacttgttc
     6481 catcgtttgc aacacacgtt ctgttttgcg gccgcttggg tcgccgatcg ttcctgttcc
     6541 gccgccaatc agaatatatg gatgatggcc tgccaattgg aatcttttca tcatcataaa
     6601 tggaatcaaa tgtccgatat gcatcgaatc accagttgga tcaacgccgc aataaagtga
     6661 aatgctcttt tcttcaacga gctcgcgaag tctttcttcg tttgtttgct gattaatggc
     6721 gtcgcgccaa gttaattcat caataatatt cattttactg acctccgtgt agttttttta
     6781 tgaaagcagg aacctgctag catgtgtaat taattatttc ttcaggatag gataggaaat
     6841 aaaaaaagtc ccttggcata taagccaagg gacgaaatct cgcggtacca cccaatttgt
     6901 atgtctagat atccaacata cctctcgaac atttaacgct gtcgcgtggc aatcactgcc
     6961 aaagactcct gaaatgtaat tcgctttaaa gcatgtactg gtttgcagcg accaccagct
     7021 ttctgaaaca ttggctttaa caactacttc gtttcgatct tcgtcttgtt attattaata
     7081 tgtgtctatc atagagcgca actttttctt tgtcaacaga aaaaggatat tttttttaaa
     7141 ttcctcattt tttctttttt gaatccgctc taattccgaa cattttattt tcaattattg
     7201 ttaaaagaaa taactttttc tgtatttttt ctgcaattta tcgagaagtc actttacttt
     7261 gcctcttatt ctttcttcgt tacaataagg aatgggacaa gtaaaaaaat gaaaaagcaa
     7321 gggacgaggt atatggaaaa aaagcaaaaa attattttag gagccacttc tgctttaact
     7381 atcgttattt taattctaag tttgtttttt gtcatccgat catctacaaa aaaagaacca
     7441 atcattcctg aaaaaaaaat aacagaaaaa gcaaaagaac cgacagatga taagcaacaa
     7501 ctagttactc aagcaaaaaa tctggctcaa agctacgatt atgaccaagc gattgcgtta
     7561 ttggaaaaag atagtaagaa cggatctact gaaacacaac agcttcttca aacactaaaa
     7621 aaggagaaag aacaactgat cgactggtct gatcctactc agatctctca tgtctttttc
     7681 cacagcttga tcgtggaccc gcaaaaagcc ttccactctc aacaggcaca aggatacaaa
     7741 gattatatgg tgactgttga agaattcaac cgttcgatcg aacaacttta tcaaaatgat
     7801 tttgttttag ttaatttgaa tgatttgatc caaaaagacg aacaaggaaa tctttccttt
     7861 aacgggcttg cgctacctga aggaaaaaaa ccattggttc tttcacaaga tgatgtcagc
     7921 tattatgaat atatggataa ttccggtttt cctagccgat tggtcgtatc aaataacaat
     7981 gaaatcaaaa atgtctataa agagaaagat aaagaagaaa tcggtgactt tgacatggtt
     8041 cctctgatcg atgcctttgt caagaaacat cctgattttt cttatcgagg cgcaaaaggt
     8101 accttggccc tgacaggtta caacggagtt ttaggttatc gaacatcaaa atctcaatat
     8161 ggagacaatg aaaaaacaaa aaaagagatt aaagaagcta aaaaagtggc ggaacagttg
     8221 aagaaagacg gctggagctt tgcttcccat acatggggtc acttgaatat gactcaagct
     8281 tcactagaag atgtaaaaaa agacaatgaa ttgtggcagc aagaagttgc acctatccta
     8341 ggaaaaacaa atattctgat ttatccattt ggtgcagaca tcagcgactg gcagccttat
     8401 tcagcagaaa atcaaaaatt tgcttacttg aagagtcaag gtttcgatat tttctgtaat
     8461 gtcgatgctt ctacaccagc ttggggacaa ttaggtacgg atttctatcg aaatgctcgg
     8521 atcaatatcg atggcattcg ttttcaatct gatttagacg gaaaaaatcc tattcttgat
     8581 ccattcatca atgtccatga tgtctatgac aaagaagcac gcgaatctgc ttgattttac
     8641 gtcatttatg aaccaaaaaa gccgaactga cattttatcg tcagtttcgg cttttttatg
     8701 ctttatttct tcttcggtgc gattcccttg atcaggactt ctgtccattc tgctgtatat
     8761 ggaagcagtt ttgcgtatat ctccggctta gaaattcctt ctaccattgc ttgaaaatag
     8821 aggatcaaga actcatccga atatttcaaa tccacttttc cttctttccg ccctcgatgg
     8881 aaaagatcaa gcatgatact gaaactttct tgcgtatacg catccatcgc gtcagaaaat
     8941 tctttttttt ctttttttgt atagtatgtc atcaaatcga tataaaattg tttgttcact
     9001 cgattgagat aacggatttt gttttcactc atggcaatca gtgtttcttc aaatggaaga
     9061 ttttccgcaa tcaacgcttt cgcttcttgc cctaaatcat tcataaatgc aaaaaatact
     9121 tcataaatca gcccttcctt gctgccaaaa tatttaaaaa tcgtcgcttt acttacctga
     9181 gcgttctcag ctaccttatc cattgtcact ccagcggttc ctatgtctgt gttcatcaag
     9241 tcaaaagctg cttgtaaaat ctctttcttt ttctcttgtg ctctcttttc aaaaccgttc
     9301 atttgtagag cctcccgtaa ttttaaactt ttataatata tatagttcaa atttattctg
     9361 aggtttatta taactatcta ttgagaaagt atcaagctag caattccttg tttatgaatt
     9421 cattgacaga aatttataaa aagaatatta tgtactaaaa taataaaaaa agttttataa
     9481 aaaggtataa aaccttttta ttaaactatt taatcttgtt tagtatatat ttttagaaaa
     9541 aggagtgggg tttttatggc agaaatcgtc aaagtcacac atttgaaaaa gagctttggt
     9601 cgtttcgaag ctttaaaaga tgtctctttc accgtacatt caggtgaagt cgttggattt
     9661 atcggaccaa atggttctgg aaaatccacg acgattcgga cacttttagg gattataaaa
     9721 aaagacggcg gaacggcaac gatttttggg caagatgtat gggaagatag tttatctatc
     9781 catgaacgtc tttcttatgt tccaggcgat atctctttgt ggggaaattt gactggagga
     9841 gcgatcatcg atctcttcat gaagcttcat ggaaaaggga gtgctcaaaa aaaagatgaa
     9901 ctgattcaac gtttctctct tgatcctaag aaaaaagcaa aaaactattc aaaaggaaat
     9961 cgccaaaaag tgggcttgat tgctgctttg gctgttgatt cggatctcta tttatttgat
    10021 gagcctactt ctggtttaga tcctttgatg gaaacgattt tccaagaaga agttgaaaaa
    10081 ttgaaagaac agggcaaatc catcctactt tcttctcata ttctcagtga agtcgagcga
    10141 ctagcggata aagtcgtgat catacgcgaa ggaacactcg atgaagaagg aacactcgat
    10201 gaattgcgtc atttgactcg ttcgaccatc actatagaaa cagaagcaga gaatagtcac
    10261 ttagcacaat tgaacggtgt ccatgacttt gtgcaaaaag gtcacctcgc tcaatttgct
    10321 gctgataacg aagctttcga tgtgatttta gctgaagcgt ccaaattagg tgtgaaaaaa
    10381 tttgaatcta ttccaccgac tcttgaggat ttattcatga gacattatga aggatgagga
    10441 ggaagcgaaa tgactgataa attttcacgc tggtccaccc ttttttctca aaaccttagc
    10501 cgtgactgga aaaagatcct gatatggcta gtcggtgtca ctgctttttc tggtggtttt
    10561 gtccctgcgt ttgaagaatt gacttccgga caaggattag ctggattata cgaaaccttg
    10621 caaaacccgg caatgattgc aatggtcgga ccaactccag cttcgaatgc tgctgagtat
    10681 actttaggag cgatgtatgc aaatgaaatg ttgctttttt gcagtttgtt tgctgctgtg
    10741 atctctgttt tacacgtggt gagccaaacg agaaaaaaag aagaacttgg tctgattgaa
    10801 cttattcgtt cctttcgagt cggacgtcaa gcaaactctt tagctgtcat cgctgaaagt
    10861 attctgatca atttgctttt agcaatatcg atcagctgta cgatgatttt tttccaagcg
    10921 gattcgatca ctgcagaagg tgcttggctt tttgggctat ctgtaggtag tatggggatt
    10981 ttggggagtg ccgttgcact gtttgctgca caactgatgc caagttcagc cagttcgaat
    11041 ggtctgtctt tagcgttttt aggtggactt taccttctac gagcaataac agatgtagct
    11101 gattcctccc tttcgatgtg gaatccttta ggctggtctt atttgaccta tccatttaca
    11161 actaacaact ggattccttt gctttatttg tttttgttca gtctaatctt gataatcagt
    11221 tcatttgttt tagaggaaca tcgagatttg aacaccggct atatccccga acgtgaagga
    11281 aaaccgtatg ctaaacgttc tcttttatcc ttgcgtggtt tattattcta tctaaataaa
    11341 gggatgacaa tcagttggct tatcactttt ggtttgatgg gggcggcata cggctctatc
    11401 tacgggaata tgcaacagtt tttagaaagt aacgacttaa tgaaacagat gtttatccaa
    11461 tctggcgtct caattgaaaa aaactttaca agcacgatca tggtcgtctt gatttgtcta
    11521 gctgctattt taccaattgc tagcatcaat cgtttattta cagaagaaac ccacggacgt
    11581 atgaatcagc tgttcgcaac aaaaatttct aggaaccaac tttattggac caatatgtta
    11641 ctagctattc tatttgctat attggcaatc ctgattagtt ctggtgcact agggctttct
    11701 gctttggctt cgatgaagga tgcgaaagac atggatctat tgatgtttct taaagccggg
    11761 ttcaatttcc tgcctgccgt tttagtgttt atcggaatta gtggctttct attcggatgg
    11821 cttcctcgaa tcggtaaact tgcttatatc tacttagctt actcctttgc actcaattac
    11881 tttggcggaa ttttggattt accagaatgg ttttccaaaa cagctgtccc tagctgggtt
    11941 ccacggatgc caaacgattc ttttgatctt tccgtgttcc ttacgttatc atgtatcagc
    12001 cttgcactgt tcgtccttgg ttctattggt tataggcgaa gagacttact agaaggataa
    12061 taaaaaagca tgtacaattt catgctagcc tccaaatctg ggtcaaaaat ccaacatttg
    12121 gaggtcattt ttttatttac aagtcttcta actgctcttt atcaatgatc cagacttctc
    12181 gattctttct ttttacataa ccattctcct ctaataattt aaattttcta gataaagttt
    12241 cgggggtcgt accgataaat gcagcaagtt ctttcatttt cattggcagg aaaaagtgat
    12301 ccttccctgt cgctttagct aagtcaagca gatagacagc gactcgttct tctacttttt
    12361 ccatcatcaa aaaagttgtc tgctgctgta cttttgttaa tttctcaacg ttgattgcta
    12421 aaagtttcag actaagggcg ggataatgca gtaagagttc cgagaaatct ttttgtctca
    12481 atatgcaaat ttccgttttt tctagtgctt cgccaaataa agactcattt ggaacgccta
    12541 gcaactggct ctctccctca tatccgcccg gctctattac tcgtaaaagc tgttcctttc
    12601 cgctagcaga taattgatac actttcatac tgccggaggc cacgatcact aattgaggtt
    12661 ctccattcgg cgcaagaatc tgttctcctt tttccacata gtgatgtttg acaagtgcgt
    12721 gtactttttc ttgatcttgc tgtactaagt gattgaacaa aggaacaaat gaaacacata
    12781 aatgatcatg actcataatc tctcctcctt ctaaacagct atttctaata aagaaacata
    12841 acttccctta ttccaactga taattttctt ttatcatagc ataaacgtca agcgaaccag
    12901 ataccagcaa atagagtgga tttctttttg tcccttgctt tattttcctt cttttgagac
    12961 cttaagtaat tgattcctat caatttttta aatatttact ttttgaataa tcaaaaacaa
    13021 accttcactc gcaagccgag agtaaggttt gtttttcgca ttgcttattt cgtgttgtct
    13081 attgaaattt ttccgcacct agcttttgat atagtggtgc tagttcttgt aaggtttcag
    13141 cggttatttg ctcaacgtgt tcgatttctt gcggatagaa gaatagttta cccatttgaa
    13201 aggttcggtc tctcatcgct tttttcaact cttcttgttt ctttgtatcg gacaaatagt
    13261 cagacaaagc taagtggtcg tcaagttcat gttctggttg cggccatatg taataatcct
    13321 tgatatcgac tgttttgctc cactctttca gtatcgcaag caactggtta tacgctgcaa
    13381 tgctaccata tcgttcttcg cttttataat gttggtacat caaatagatt tggtattgtt
    13441 tttgattcaa caaaactgct agacaggcat tctcgtcttg acgagattcg cttcggtacg
    13501 cgctccaaaa atgactgcgt aaattccagc cattcgtcca gctttcgatt ttaggtttgc
    13561 tcatgccgta catatcaggc aaaagtgcag ctgtctggag ctgaatctct ttccattttt
    13621 gccagtgttc tttatattct ttcttgattt gttcaatctt atctgttgga tggctctctt
    13681 tgagctgttt gaatgcgtag attggtcgat caaacaactg ataatctgat tttccaagtt
    13741 ccattgtttc gcctctttcc gttatctttt gtattctacc tgaattttgc gatatggaca
    13801 aatagaggtt gtgaaaaagc tgttctgcat caagtcataa gaacagccaa acaaaaaact
    13861 gcgatgagca tcaccgcagt tttattgaac ttaaggttga ttgatcacat ctaaaagcgt
    13921 tgaaaataaa atggcactag aagcagctcc tgggtcgata tgtccgattg cacgctctcc
    13981 tagataggaa gctcgtcctt ttttagctac caagactttg gtgtgttctt ttgcctggtc
    14041 aatgatttct tttgttaaat tccctgcctt caatgcctct gtgactggca gccaaacatc
    14101 taacatcgtt ttatcgtcag cttctgcctt tcctcggctt tgaatacccg ctgttccctg
    14161 ctcgatcact tcgcctaatt tttcttgaga atcaatagaa tcgacctctt ttgtcgcttt
    14221 catcatgttc atgaatgcag atccgtataa cggaccagaa gccccaccga ctttcgatat
    14281 catcgccata gagaatactt tgaatgtatc gctgattgtt tcaggatgat cggcttgaaa
    14341 agcttcttca taagctgaaa cccctcttcc catgttattt ccatggtctc catcgccaat
    14401 cggggtatct agatcactga gatattgttt gttctgattg attgcctctg caaattgcgt
    14461 gagccattct tggatttctt gaacggttag tttcatatta tcaccctttt atcttgagat
    14521 tttttaccat gaaatcgtct gtacattgct ttctaaagaa tctttccatt gtgtctccgt
    14581 caagtcgatc agtgttagag aaagaccttg catatctagt gaggtcataa aattaccgac
    14641 ttttcggaaa actacattga cgcctctttc ttccaacaga gctaaaacat cattcatgaa
    14701 cacgaactgt tccatcaaag gcgtcccgcc cattccgttg actagtacac ctgcttcttt
    14761 tggtaaattc gagtaatcat ctaaaatctt agtaacaagt tcctttgcca gtactttaga
    14821 aggctgcatc ttttctcgac gatagcctgg ctcaccgtgg ataccaacac catactcgat
    14881 ctcatcttct cctagttcga atcctggttt ccctacttct ggtacagttg ctgctcgaag
    14941 cgctagaccg atcgtcttag ttgcctgtac gaccttttct cccagttctt tcaactcagc
    15001 tagggaagca ccgtttcttg ctgcatcgcc cacgattttg tgtacaagga cagtacctgc
    15061 aactccgcgt tttccagcag tatacgtact attttcaacg gcgatatcat catctacgat
    15121 cacactttct acttcaatat cgtccatagc agctaattcc tttgccatat cgaagttcaa
    15181 tgcatcccct gtataattct taacgatcag caaaactcct tttccactat cggcttcctt
    15241 aatagccgtc tgaatctgat ctggagttgg agaagtaaac acatcaccaa gcaccgctgc
    15301 acttaacatc ccttccccta caaacccggc atgggatggt tcatgtccgc ttcctccacc
    15361 agaaaccaaa ccaacttgtt ccgctttctg attcttggct acaacacggg aagattctac
    15421 acgatgaaca agttctggat agctttttac taatccttcc agcatttctt cgacaatatt
    15481 gcttggatca ttcatgattt ttttcaattt attcccatcc tttctttccg gcattttgtg
    15541 cttctgttaa gatttgctga gtatcatctg ttataccggc agtgatggct gctgcaaaag
    15601 ctccttccac taaaggcgca tccaccagat gataacgttg ctgctgctct tcttccaaca
    15661 tgtcttttgc cagttccgag ttcaataccg cgctaccgat atccgcaaaa acaaaataac
    15721 tagctgcatc gcttgattca ttgactgctt ctacgatttt catcgggtct gatccgatct
    15781 cgccatttat tccgccgaga gaaaaaattt gcacctcttc ggatttttgc atctgctcaa
    15841 tcatttcttt aataccatct gttacttttt gactatgaga aataagcaaa atactttttt
    15901 tcacaagaat cttcctttct tttacatagt tgctaacgat tggtttcgct ttcattaatg
    15961 aacaattcaa gtatataata aat
//
LOCUS       DAPBBR010000057        15559 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPBBR010000057 DAPBBR010000000
VERSION     DAPBBR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.060"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..198)
                     /locus_tag="RD488_002138"
     CDS             complement(<1..198)
                     /locus_tag="RD488_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7658197.1"
                     /translation="MKINYTVDLVSFSLVINFCLFSLRLFIEGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(503..1735)
                     /locus_tag="RD488_002139"
     CDS             complement(503..1735)
                     /locus_tag="RD488_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDT7658198.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSAAGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVIDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1992..2561
                     /locus_tag="RD488_002140"
     CDS             1992..2561
                     /locus_tag="RD488_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7658199.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2739..3179)
                     /locus_tag="RD488_002141"
     CDS             complement(2739..3179)
                     /locus_tag="RD488_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDT7658200.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLSGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3337..4101
                     /gene="map"
                     /locus_tag="RD488_002142"
     CDS             3337..4101
                     /gene="map"
                     /locus_tag="RD488_002142"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDT7658201.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4133..5056
                     /locus_tag="RD488_002143"
     CDS             4133..5056
                     /locus_tag="RD488_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDT7658202.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVIGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            5132..6271
                     /locus_tag="RD488_002144"
     CDS             5132..6271
                     /locus_tag="RD488_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDT7658203.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFTAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6264..7064
                     /locus_tag="RD488_002145"
     CDS             6264..7064
                     /locus_tag="RD488_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7658204.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTKYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            7064..7891
                     /locus_tag="RD488_002146"
     CDS             7064..7891
                     /locus_tag="RD488_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7658205.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIVYDNSPQ
                     RQQNEMFEKENIVYHHDPQNPGLAVAYNFALSQAYEGTRCLVTLDQDTRLDDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7869..8603
                     /locus_tag="RD488_002147"
     CDS             7869..8603
                     /locus_tag="RD488_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7658206.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRIHLITALIKRKWFKR"
     gene            8703..9569
                     /gene="rfbA"
                     /locus_tag="RD488_002148"
     CDS             8703..9569
                     /gene="rfbA"
                     /locus_tag="RD488_002148"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDT7658207.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9583..10155
                     /gene="rfbC"
                     /locus_tag="RD488_002149"
     CDS             9583..10155
                     /gene="rfbC"
                     /locus_tag="RD488_002149"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDT7658208.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            10177..11205
                     /gene="rfbB"
                     /locus_tag="RD488_002150"
     CDS             10177..11205
                     /gene="rfbB"
                     /locus_tag="RD488_002150"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDT7658209.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11303..12154
                     /gene="rfbD"
                     /locus_tag="RD488_002151"
     CDS             11303..12154
                     /gene="rfbD"
                     /locus_tag="RD488_002151"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDT7658210.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            12189..14222
                     /locus_tag="RD488_002152"
     CDS             12189..14222
                     /locus_tag="RD488_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658211.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSILWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14266..15546
                     /locus_tag="RD488_002153"
     CDS             14266..15546
                     /locus_tag="RD488_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HDT7658212.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGVLVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4755 a         2684 c         3237 g         4883 t
ORIGIN      
        1 ttttgtataa gtagacattg tagtttctaa actgctatgt cctaaacgtt tcgatacgct
       61 aagtatattt actccttgat aaagtaaaat agatgcatgc gtatgtctta gtccctcaat
      121 aaacagtcga agagaaaata ggcaaaaatt gattactaaa gaaaaactta ctaggtcgac
      181 ggtgtagttg attttcatac ttcaacagat tcgaattaaa cgatttcgat tggcttatac
      241 cagtcctatc cgacgaaaga tatatcgttc ttaactctag cggtataact tgaagcttta
      301 cgtaaagcca atgggaatga actggagatg actttttatt atttttagta atagctgatg
      361 ggttaatact tacaactttc cttttcaaag taccatataa aaaaacggtg gggttgttta
      421 gcgaaataaa ggatctaagc caatagctta gatcctttat tctatgcttt atattatttt
      481 ttgcatgtgt gcgaaagtat actcaagccc aatcgccatt tcggaaaatc ggtactgtag
      541 agccatcttc acggattccg tcgatatcca tcttgtcaga tcctaccatg aaatctacgt
      601 gggtttgact tctattcaat ccagcttctg ctaattcttc atcggacatt tctgtaccgc
      661 ctttcacact gaaggcataa gcagaaccta gtgctaagtg attcgatgcg ttttcatcaa
      721 ataatgtatt gaaaaagatg atgccagatt gagaaatagg tgaagggtca ggtacaagtg
      781 cgacttctcc taaacgacgc gcaccttcat ctgtatcaag cagttttgct aagacatctt
      841 ctccttgttc ggcagaaaaa tcaatgactt ttccatcttt aaaagtaaat ttcatacccg
      901 agatgatggt gccagcataa ctcagtggct ttgtacttga aatgtaacca tctactcgat
      961 gactgtcagg tgctgtgaac acttcttccg tcggcatatt tgccatgaat ttttctccac
     1021 gagcattata gcttccagcg ccttcccaaa gatggttttt aggcaatccg ataatgatat
     1081 ctgtaccggg agcagtatag tgcagggcag aaaattgttc tcgattcaat tcttctgctt
     1141 tttttgctaa tttttcatca tgcttcttcc atgctaagac agggtcttct tcatagacac
     1201 gagtcgtttt gaaaatctga tcccataatg cctcaacttg tttttcttct ggcagttctg
     1261 ggaagacttt tgctgcccat tgtttaccag ccgcagccac gacagtccaa ctgactttat
     1321 ttgcttgagt tgccttgcgt aaattcatta gtgctttgcc agccgctgat tgataagacg
     1381 ctactcgatg gctatctaca ccagcaaatg catcgggatc ggcagaaaca acactgatcc
     1441 tgcttgctcc tttttcaagc cattcatccg cttgatcgat tttagattgt ggtacattct
     1501 caatacgatc cgttgcagca tgtaaaagaa attctctttg gatctggtcg tcagtccatt
     1561 gaacgataac ctcagcggct cctagtttat aagcttcttg tgtgatcaat cgagcaaggg
     1621 gtgcctgttc cacgctgatc tgtaaaacaa ctgtgtgtcc tttttctgtg gctacgccag
     1681 tttctgcaat taagcgtgca tattttttta gaagttcatt aaaatcagat aacataataa
     1741 aaattcctcc tcaccatttt ttctggtaac tattagcatg ataccattta attatgattc
     1801 aaacaatgag gcctttaaat aaaaaaaaga ggttattttt ttaaggttaa gtttcatgat
     1861 atatgttact acttgctatt tcagcttgtg aagaaaatca aaaactaatt ttgcatatca
     1921 aaaaaaacat gttacaatga aattaatcaa tggtggaagc gttataaaaa aattaaggag
     1981 attaaaaaaa tatggcaaga aaaaagacga ttactagaga acagattttg gcagctgctt
     2041 atgaagtagc tgccaccgat ggatttacac gatttactgc gagaaacatc gcgaacaaaa
     2101 tgaattgttc cacgcaaccg atttatcttg agtttaaaaa tatggatgac ttgagacaag
     2161 ctctttttga gcagatctat gatcatttac aatatgaagt gttcactgtt gagcatacag
     2221 ggaatacgat tatcgatctt gcttttaatt atatccattt tgcaagaaga gagaagaagt
     2281 tgtatcgttc actgtactta gaagaatatg gtggaggaaa agagatgcag aatttctctt
     2341 atacttactt tgtgaataca gtgaaacgcg atccagctta tgtgaatctt tcagaagagc
     2401 agatcgaatc tttgtataat gggacatgga tcatagctac tgggatcgca gctttgatgt
     2461 cttcaagcat catccatcca actgatgaac agattgaaaa gatgatacaa gacagtatag
     2521 atgctatctt gaaattcaaa gaaccaatag aaatcgattg aatatactca aaagttccac
     2581 aaatcagtag ataacaagag atgtgtcaaa ataaggaaaa gttcgttttt cttacagcgt
     2641 atgcattttt aactcccgaa gaactcttcc atgaatgcaa tgaataaaag agccgtacag
     2701 attgaataaa tctggatggc tcttttattg caagtatatt aaatttttgc gactagttct
     2761 ttagcgaaag cttctaaatt ttcgatatct tcttcttcag cattcagatc cactttaaca
     2821 ttttcggctc cttttgatgc gcctgttttt gcaaaagcag catcgaaatc atccaccgat
     2881 ttgcagaatt catcgtaaaa agtatcacca gatccgcaga caccgtaaat ttttcccgat
     2941 agatccaatt cttgcaagtc ttcataaaag tctacgatct catcaggcag atcgccatca
     3001 tcgtatgtat aagtagctac tacgcaaata tctgcctcct cgaattcatc tgcatctact
     3061 tgggtacatt cgttgatttc gacttcgata tccagatttt caaatgcttc tgcaacaata
     3121 tcggcgattt cttcagtgtt tcctgtcatg ctagcatata cgatttttgc taaagccatg
     3181 atgtgcctcc tcgtttataa ttatttaaca attatgaatt ataccaaaac atcattgaaa
     3241 agaaaataaa acctagagac acctggggaa tgtcatttgg ctaaatgtat gccgctatgt
     3301 taaaatgaga gggatttgta aaaaggagac gaaaatatga ttactttaaa atcagcacgt
     3361 gaaattgaaa tgatggcaga atctggagct ttattagcag atgtacataa aaatctgcgt
     3421 gattttataa aaccaggaat cacaagttgg gatattgagg tatttgtcag aaactatatc
     3481 gagagtcatg gcggaattgc tgcgcaaatt ggctttgaag ggtatgaata tgcgacttgt
     3541 atcagtataa atgatgaaat ttgtcatgga ttccctcgta aaaagccttt gaaaaacggt
     3601 gatttggtaa aagtcgatat gtgtattgat ttgaaaggcg gcatttctga ttcttgttgg
     3661 gcctatgtag ttggagaatc tacacctgag atcgaccgat tgatggaagt aacgaagaaa
     3721 gctttgtaca tcggtattga gcaagcacaa gtagggaatc ggattggtga catcggtcat
     3781 gctatccaaa cttatgtaga aggcgaaaat ctagcgatcg ttcgtgattt tattggtcat
     3841 ggcgttggtc ctacgattca tgaagaacca gcagttcctc attacggaga agctggaaaa
     3901 gggttgcggt tgaaagaagg catggttatc acgatcgaac ctatggttaa taccggaact
     3961 tggaaaatga aaatggatcc taacggctgg actgcgtata caagagacgg cggactttct
     4021 tgccaatatg aacatacatt ggctattact aaagatggtc caagaatttt gacatcacaa
     4081 ggagaagaag gcacttattg atctagccag tcaataggta cgggagaggt acatgaaagt
     4141 ttggaacaaa ataaaacaaa atgaaaatct gatgcgcttt attgagacga ctcaaaagcg
     4201 catcactgat tcagaaatga gtacgacctc tgtcgtcgtt gcttattatt tactcttgtc
     4261 tttatttcca ttgattattg cttttggtaa tattttaccg tttctccaca tcgatcaaga
     4321 gactgtactg acctatttac gagaagtgat tcctgagacc gtttaccagt ttatcggtcc
     4381 tgcaatcaaa gaccttttga cacaaagttc aggaggcttg ttatccgttt ctgcattagc
     4441 ggctttatgg tctgcaagtc aaagtatcaa tgctttgcaa attgcgatga ataaagcgta
     4501 tggcgtagaa aatagaaaaa attttttgat cgtccgtttc ttctcactaa ttgtcattgt
     4561 cttgttcatg attgctatta gtggggtaac tatcgttatt gggttgggac agctgatttt
     4621 ggatgctatt cagccaatcg tacaaatacc tgtgaacttt atcgatcagt tccaaacttt
     4681 gaagtggcca atcacattgg tagctttatt tgtcatcatg ttcttgattt atttaattgt
     4741 ccctaatgct cagttgaagt tgaagacgat cattccgggc acgatcttcg ctactgtcgg
     4801 ctggatgctg ttatcacaag tgtttagtat ctatgctagg tattttgcaa cgaggatcag
     4861 cggttatcag atcataggaa gttttattgt actcatgctt tggcttaatt ttgctgctac
     4921 gatcatcatt ttgggcggaa tcatcaatgc agttgttcaa gaatacgtga cgggtcatca
     4981 aatcaaaaaa cgtcgagatc caagccgaaa atggttcaat aaattgaaaa ctaaattttc
     5041 tcataaaaaa aagtagaaac aagagttctt attgtaaatt tatatcagta atttataata
     5101 attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta tggttataag
     5161 attttttctg acaattttat tatcactgat attaacacct gtattcaaaa tcatttcagt
     5221 acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc caatgccttc
     5281 agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct tattccgtaa
     5341 aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa tcatagtcac
     5401 aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag ggatcttgat
     5461 tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca cgcttccttt
     5521 tattggatat atccaactag gctggcttag ttttcccgta acgatttttt ggatcttcgg
     5581 tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag ggatttcatt
     5641 gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt ctacagtgta
     5701 tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc cttacaattt
     5761 ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt ttatgatggc
     5821 cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt ctttgctgat
     5881 cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa aagcaaaccg
     5941 tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca gtttaggctt
     6001 tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt ctttcacagc
     6061 tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg ccatgttgtt
     6121 tactgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc agtttatttt
     6181 aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac agaaatattt
     6241 gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc cttattagta
     6301 ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt tcaactgtaa
     6361 aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc gagtacaaaa
     6421 aaagactaac aaagtatagg aaatatccct acatcgatat ctattttcat gatgaaaatt
     6481 ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc tatggcatta
     6541 tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc ttgttattga
     6601 aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat ggaacaactc
     6661 agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt gtgcctttca
     6721 aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga ggattgccta
     6781 ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct gatattgata
     6841 aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa gacaacgact
     6901 tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt tatgcagtta
     6961 tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg tttttgactt
     7021 ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac cagaaatatt
     7081 agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg gaccattaag
     7141 caaagcactt agcgaaaagc aaattcagct tattgtttac gataatagtc ctcaaaggca
     7201 gcaaaatgag atgtttgaaa aagaaaatat cgtttaccat catgatccgc aaaatcctgg
     7261 tttagcggtg gcttataatt ttgcgttgtc tcaagcatat gaaggaacac gttgtctcgt
     7321 cactctggat caggatacga ggctagacga cgattatttt gaactattgc gtaaagtaac
     7381 ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc gacaagtttc
     7441 tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag ttgaaggccc
     7501 aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca aatttctaaa
     7561 aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt ggctgttttg
     7621 gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg aacatgatct
     7681 ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt tacaagcaga
     7741 aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac gacaattatt
     7801 gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc ggatgacttt
     7861 gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt atagctacct
     7921 ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag ctttcagcag
     7981 aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat atattaactg
     8041 aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa ggattgatcg
     8101 ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg gcagaccaag
     8161 atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag cagaatccgg
     8221 atcagctagt agtagtttct gatttgatca ttgtggacag cgagctgcaa gagatccatg
     8281 attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg ataagaagtc
     8341 actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt ttgccgatcc
     8401 cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag aagactgggt
     8461 tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt gagattgaaa
     8521 cacattctaa attacggcaa aaaatttctt ggcgtattca tctgattacg gcgttgatca
     8581 aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt ccatgacaaa
     8641 tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga gaacatatat
     8701 ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct ttaacaaagg
     8761 caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat ccaatgtcta
     8821 ctctgatgtt ggcaggaatc aaagaaattc tgattatttc aacgccacaa gatacaccac
     8881 gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa tatgcagtac
     8941 aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt attggagatg
     9001 atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg tctaaaatgt
     9061 tgcaacgagc agcttcaaaa gatacaggag cgacagtatt tggctatcat gtcaatgatc
     9121 cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg attgaagaaa
     9181 agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat gacaatgagg
     9241 taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag attacggatg
     9301 tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga cgcggatttg
     9361 cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt atcgaaacaa
     9421 ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac cgtatgggct
     9481 acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat caatacggtc
     9541 aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt aacagataca
     9601 aaattaacag atgtcaaaat cgtagaaatg gatgtctttg gcgatcatcg cggtttcttc
     9661 acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga ctttgttcaa
     9721 gacaatcatt cactatcagc tgaagctggt gtccttcggg ggcttcattt ccaaaaagga
     9781 gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga tgtagtagtg
     9841 gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt atctgaacat
     9901 aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac tttgacacca
     9961 aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga tgggggcatc
    10021 gcatttgatg atccagatct agcgattgat tggccaattg atccatcaag agcgattatg
    10081 tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa tccatttgtt
    10141 tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat tgttaccgga
    10201 ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca tccagaagtg
    10261 catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt ggccggactt
    10321 cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt agtggaccgt
    10381 ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa cgataattca
    10441 ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac acttttagaa
    10501 gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt ttacggcgat
    10561 cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa attcactgcg
    10621 gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc agatctgtta
    10681 gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg ttcaaacaac
    10741 tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgag tatcttaagc
    10801 ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat ccatacgaat
    10861 gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga aacctatctg
    10921 atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt agaaatgatg
    10981 ggccaaccaa aagacgcata cgaccatgta aacgaccgcg cagggcacga tttgcgttat
    11041 gcaatcgatt cgacaaaatt gcgagaagag ctaggttggc agcctgagtt tacgaacttc
    11101 cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg gtggaaaaaa
    11161 gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag aggaaatttc
    11221 actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt tttaaaataa
    11281 aaatcaagga gcggataacc atatgttttt attaactgga ggaaatggac aattaggtac
    11341 agaattgcgc catttattag atgaaaaaaa tctgccatat gtttcaacag atgcaaaaga
    11401 cttggatatc acagatgctg agaaaacaat ggcttatatt acagaattaa aacccgatgt
    11461 tattttccat tgcgcagctt acacagcagt agataaagca gaagaagaag caaaagaatt
    11521 agatgagaaa atcaatgtcg atggcacaag aaatgtagca cttgcagcaa aagctgtgaa
    11581 tgcacaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca aaaatgtaga
    11641 atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga aattattagg
    11701 cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt cttgggtttt
    11761 cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa cccgcgacaa
    11821 actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt tggcagaatt
    11881 tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt cgaacgaaaa
    11941 tagctgttct tggtatgagt tcgcaaaaga aatattgaaa gatacagatg tagaagttgc
    12001 acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt cagtcatgag
    12061 cctgaaaaag acagaagcgt taggttttgt cataccaact tggcaagaag cacttgcgca
    12121 aatgctggaa gctgccaaaa aaatgaataa gtaatttcct ttttatcaaa tagaatttgg
    12181 agcatgatat ggaaaaacaa acaagaagtg cacgacgaaa agaaaagcca aaagcgaatc
    12241 aggcagattc gaatttggtg cttgacctgt ttctaaaact ccgctatctt attggcgttt
    12301 tagtcatcgt ggtcatcgtt acttttaatt taaacggaag ttcacttggt gtttgggata
    12361 aatatgtgtc gcaaagagac gatgggaaaa aaactgatgt gatttttgga cagaatcggg
    12421 aagtgcggtc agacgaatgg ctggtgcaga caccttttta cctctcacaa gctgaagagg
    12481 acttttcgtt ggtgaacgag gattattcat taaacggaca aaacatgatc attgcgtata
    12541 attctcctgt aaaggatatt acggttatcg gaaaaccatt caactgggga ttctttttcc
    12601 tcggaagaga tcgaggactt tccttttatt gggcgatgaa attagtcgtc atggtcttgc
    12661 ttggattcga agtactgatg atattaacga agaggaaaaa agctctatcg ctaatcggtg
    12721 catttgcgct gacattttct ccagcagtcc agtggtggtt catgcaacat gtgggcgatt
    12781 tgattttctt tactttggga ctgatgattg ctttttatca ttatttctac aatcatgata
    12841 aaaaatggct acgaacgttg atgatgcttt tggtggttat tttcggtatt gggtttattt
    12901 tagtgattta cccagcccat caagtgatgc tggcgtactt gctgattttt tattttgttg
    12961 gcctgcttat ttactatagc aagaaagttt catgggatct gttggatgta gtgttgattg
    13021 gaggggcagt tttatttatt ggcggagtca tggttcattt ctggctaacg tcaaaagacg
    13081 cattgttagc ttctttgaat accttatatc caggaaaacg ggtaagtact ggaggaaagt
    13141 ggacgattgg cgaatttttt tctttcctta caaattggaa aattcctttt gaagatatca
    13201 actattcgaa taactctgaa gtggccctgt tctatcactt ttttccaact gtattcctag
    13261 caagtccatt tgtgttattt ggcaaaaaag atagcgaaca aaagttactg ggacgtattt
    13321 tgatgatttt ttgtctgttt tctatccttt ggattaccgt tgggttgcca aaatggctag
    13381 cagaaatcac tctgctgtct tatgttcctc cattaagagc catccttact tttagttttg
    13441 cggcttgttt attatcgatc tggtttatcg cttatatttg gagagaagat gttattccta
    13501 tttggtataa attcattttg ttggcagtaa atgcatggtc ttatttctat gcgattacgc
    13561 attcgaaaat ggataattat ttttcggatt ttgaaaccat cgcagttgct gtgttgggaa
    13621 cagtgatttt agcttttgca ttatttggct ggagacgctt gttttacctc gcttttgtcg
    13681 ccttagttat cgtatctggc tttttcgtca atccagtcgt agaaggtaca ggagcgattt
    13741 ttgaaaaaac actggcaaaa gaaatccaaa aaatcgatca acaagatcct ggtaaagttt
    13801 ggttgtctga agatgaatta tataacttca ccccaacatt gggagtgaaa tccttcaata
    13861 cagtacgctt ttatccagat atagctgcat ggaagaaaat cgatccgaaa gaagaatacg
    13921 agaagtatta taatcggtat gctcatacaa gagcttttat cgctaaggaa gatacaaagt
    13981 tcattttaga tcgtccagat atgttttcgg tcacgttgaa ttttgaagac gcagaaaaat
    14041 tagggatcga ctatgtgatc agtaaacgac cattaactga ttacaaccaa ttatatgaag
    14101 cgcagttcac gcagctatat ggaccggata aagacggtta tatgattttt aaagtagaat
    14161 atccggatta tccagatgta ccacaaacac aaactcagga aaatcagcta gtcgtacagt
    14221 aataggctag ctgagaataa tcctgaaata ttagtagaaa ggagagtgaa gataattcaa
    14281 gcaatcgtac aaaaatttgt caacaaaatg agtgtcggtt tcttgctttt gttgctgacg
    14341 ctagtctttt ttgtttggac agcaggggta ggttttccag caactttgtt tatatataac
    14401 aatagttcat tacttatcgc ttttagtgtg gctattttgc tcattttaaa tgtttataaa
    14461 gcaaaaggcg tcgattttct ttatctaggt gttgcgcttg cccttttcat tttcttttct
    14521 tactttcggg aattaagaaa tgagtcttta tttggagact tactgtttcc tttgattatt
    14581 ttattttgtt tagtaattaa atggatcgag tggacaaaat gggatcgcgg tatttatctg
    14641 attgtcttta cggtcttcct cggaatcacg ttatatcgtg tatttacaga gatccaagta
    14701 ccagaaggac aaagcatctg ggctccaggc aattcgcttt ctgatatttg gatcaatacg
    14761 aatacaatcg gaagttcttt gatgactctt gctttattga tcagtggatt tgccagttct
    14821 tttgaacgat ggtatgttcg aatcatcggt gggatagcag tcgttgcagc ctttttaggt
    14881 atttgggtct gccaatctag aggtgtatta gtcgcgttga ttgtttttgc gatattggat
    14941 cttttaccta aatcgttgat gcgtgtcatt cgtgcgccat ttattgccta cacggttacg
    15001 attcttttag ctttgccgat ttcttatctg gcggctgtct ctgaaaaagt caatttgttt
    15061 accggtcgag aagatatttg gcataaattc tatcagacgc taggagaaaa atctgaacaa
    15121 gttttactag gaatgaaaac atttatcttc cagcgaggaa accaattttt aggaaaccac
    15181 aatagttata attctatttt gaatatctat ggattgatag gatttgggat tgctgctttg
    15241 ctgcttatcc tttttattgg tcgcttaacg ttgaaagcag atttatccaa cgggcagatg
    15301 acttttatct gggccttttt tgcggtgatg atgcagtcat ttatggagga tacattgact
    15361 tcatacccat gggttccgat tatttatatc ctgttggcta tggccgttca tcgatatgat
    15421 gaaccagaag ttgcggagga attctatgtt atggaagagg catatgacga tatgacttat
    15481 gatgatacat cttatgagga acaaccagat agcgctcatt cttccaggat ccaacgctat
    15541 cattgatagg cacaaaata
//
LOCUS       DAPBBR010000058        15266 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPBBR010000058 DAPBBR010000000
VERSION     DAPBBR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.061"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            333..947
                     /gene="gmk"
                     /locus_tag="RD488_002154"
     CDS             333..947
                     /gene="gmk"
                     /locus_tag="RD488_002154"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDT7658213.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            952..1257
                     /locus_tag="RD488_002155"
     CDS             952..1257
                     /locus_tag="RD488_002155"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDT7658214.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            1510..3918
                     /gene="priA"
                     /locus_tag="RD488_002156"
     CDS             1510..3918
                     /gene="priA"
                     /locus_tag="RD488_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDT7658215.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3933..4424
                     /gene="def"
                     /locus_tag="RD488_002157"
     CDS             3933..4424
                     /gene="def"
                     /locus_tag="RD488_002157"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7658216.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            4417..5355
                     /locus_tag="RD488_002158"
     CDS             4417..5355
                     /locus_tag="RD488_002158"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDT7658217.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            5355..6713
                     /gene="rsmB"
                     /locus_tag="RD488_002159"
     CDS             5355..6713
                     /gene="rsmB"
                     /locus_tag="RD488_002159"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDT7658218.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6726..7466
                     /locus_tag="RD488_002160"
     CDS             6726..7466
                     /locus_tag="RD488_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDT7658219.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            7463..9532
                     /gene="pknB"
                     /locus_tag="RD488_002161"
     CDS             7463..9532
                     /gene="pknB"
                     /locus_tag="RD488_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDT7658220.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            9697..10596
                     /gene="rsgA"
                     /locus_tag="RD488_002162"
     CDS             9697..10596
                     /gene="rsgA"
                     /locus_tag="RD488_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDT7658221.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            10609..11259
                     /locus_tag="RD488_002163"
     CDS             10609..11259
                     /locus_tag="RD488_002163"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7658222.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            11260..11898
                     /locus_tag="RD488_002164"
     CDS             11260..11898
                     /locus_tag="RD488_002164"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDT7658223.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            12053..12907
                     /gene="mreC"
                     /locus_tag="RD488_002165"
     CDS             12053..12907
                     /gene="mreC"
                     /locus_tag="RD488_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDT7658224.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            12911..13420
                     /gene="mreD"
                     /locus_tag="RD488_002166"
     CDS             12911..13420
                     /gene="mreD"
                     /locus_tag="RD488_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDT7658225.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            13675..15249
                     /locus_tag="RD488_002167"
     CDS             13675..15249
                     /locus_tag="RD488_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7658226.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT         5121 a         2865 c         3319 g         3961 t
ORIGIN      
        1 gtattaagcc aaatttatgc aaaaatgtga gaaactattt tcacaaaatt tttcttcata
       61 ctcgaaacta atcggcttct tcacgacctc ttatacacgg cgttcaaaag cttgcatctg
      121 cgataataac cccaaccaaa cgaaaaacat gagaagctgt ttatgtttgg ctgttcttat
      181 tacttgatgc aggacagctt ttttacgacc tcttggtaca gggtagcttt tttaccaatt
      241 tctagctata attaaagata accttgaaag ttgcagaaaa aaagtgcaaa ataaacgata
      301 agtacaaaaa gactagttga aaggacgtcg tcatgtcaga gcgtggatta ttaatcgtgt
      361 tgtctggtcc atccggtgta ggaaaaggca cagtacgaaa agcaattttt gagagtgagg
      421 ataatgattt tcagtattcg atctcaatga ctacccgtaa aatgcgtgaa ggggaggtcg
      481 aaggcgttga ttatttcttc cgaagcaaag aagagtttga atcaatgatc gaagctggag
      541 agatgctgga atacgcagaa tatgtcggga attattatgg aactcctttg tcatatatca
      601 acaagacatt ggatgaagga aaagatgttt tcttggagat tgaagtccaa ggagcaaaac
      661 aagtcaaaga aaaagtgccc gatggtgtat tcatcttttt gactccgcca gatttagcgg
      721 aattaaaatc acggatcgta ggccgaggaa cagatgcaga tgaagtaatc gaagaacgaa
      781 tgaaagttgc aaaagaagaa atcgaaatga tggctcttta cgactatgct gttgtaaatg
      841 atgaagtgcc gctagcagtt gaacgaatca aaaacattat tgccagtgaa cattttcgag
      901 tagatcgcgt aatcggtaaa tatattaaaa tgttaaagga gatgtagtct tatgatgtta
      961 aaaccttcaa ttgactcact attagatcgt gtaaattcaa aatattctct agtgatttta
     1021 gcaagtaaac gcgcgcatga attggatgca agtgcacagc ctactctaga ttcttttgat
     1081 tcagtaaaaa gcgtcggtca agctttagaa gaaatcgatg caggaaatgt agtcaatgat
     1141 ccacatcctg aattaaaacg tgaacgtttg aagatggaag aagaggaacg tcaagcacaa
     1201 aaagagcgtg aacaacacga attggaatca cgtatccgtg aagagcaaaa aatgtaataa
     1261 agaaaaatag agcgaacatc taaaaagaaa agcaaaccca gctgtttcct tttcaaacat
     1321 tcgccactta ttgtctggta gaaaaggctg tgtctgaact ttttgacaca gttctttttt
     1381 ttcttatctg ctgttaattt tttgttagga tttggcagaa gataagacaa atccatcgat
     1441 ctctagtaaa ataggcaagg aactttttgt cgcttgataa gaaaagacaa aaaaaggagg
     1501 aaacgaacca tgacattaac agctgaagtc attgtggacg tacctactat gcagaccgat
     1561 cagccattca cttatttggt tccctctgaa atggaaacag ctttgcaagt cgggatgcga
     1621 gtagaagtcc cttttggtaa tggcaatcgt catgtccaag gatttgttat ggctatccaa
     1681 aaatcagaag aatcagctaa tccatctttg aaggcagtta ttcgtttgct agaccttgct
     1741 ccggtggtca atgaagaatt actttcatta gctgattata tgaaaaaaat tacttacgca
     1801 ttcaaaatca cttgtctaca aacgatgctt ccgagtgtga tgaaagcaga atatgataaa
     1861 ttgatctatc ctttggcaga cacaccagaa gttcaggtat tgtttgatca gcgagaagtg
     1921 atttcctgga aggaagcaga agaagaaggc agcctttctc aattgattcg ctggcgccaa
     1981 gagcaattag tagatatcaa atatgaagtc catacacgaa ataaagtaaa aacgattcgt
     2041 ttggtccgtt ctttgttaac tgaaaagcaa atcgaagaag aatgggcaaa attacggcaa
     2101 aatgccaaga aacaaaaaga acttcttttg tgtttatctg aactgagcca agaagaacca
     2161 attgcttatt tcaaaaataa aggaatcagt actgctgtct tgaatcaagg aaaagaaaag
     2221 ggctggctgg agtttataga atcagaacgt tatcgcgacc cttataaaga ccgagtattt
     2281 gaccaaacga cggcattgga actgaatgca gaacaaaaaa atgctgtcga acaaatcatc
     2341 acagcaggtc agcagcaaaa agatcaggtc tttttgctgg agggaatcac tggcagcggg
     2401 aaaacagaag tatatcttca ggcaatcgct gatgttttgt cagaaaataa aacggctatt
     2461 atgttagtgc ctgaaatcgc attgactccg caaatggtcg agcgattcaa aggacgcttc
     2521 ggagaatcag ttgcggtctt acatagcgga ctttcccaag gtgaaaaata tgatgaatgg
     2581 cgcaagattg agcgggaaga agcgcaagta gtagtaggcg cacgatctgc tatttttgcc
     2641 ccgctgaaaa atatcgggct gatcattatc gatgaagaac atgaatcaag ttacaaacaa
     2701 gatgagacac cgcgttatca tgcgagagat ctagcaattt ggcgcagtaa atatcatcat
     2761 tgcccaatag ttctaggaag cgcgacgccc tctttagaat caagagcacg agctcaaaaa
     2821 ggcgtttatc agttattgca gttaaaccac cgagccaaag cagctgcaca gcttccagct
     2881 attgagatcg tagatatgcg tgaagagttt cagaatcatc ggacctctac tttttctgct
     2941 aatttgcagg aaaaaataca aaatcgatta gacaaaaaag aacaaactgt cctactgctc
     3001 aatcgtcgag gatattcgtc ttttgtgatg tgtagggact gtggatttgt tcttccatgt
     3061 cctaattgcg atatctctct tacactgcat atggatacac gttcaatgcg ctgccattat
     3121 tgcggacatg aagaacctat tcccaatcgc tgtcctaatt gtggcggcaa taaaatccgc
     3181 tactatggaa caggtactca aaaagtagaa gaggaactcc gagaacttta tccgcaagct
     3241 aggattttgc gtatggatgt agataccact cgaagaaaag gggcacacga acagatttta
     3301 caaaaattcg gtgcaaaaga agcagatata ttattaggga cacaaatgat tgctaaaggt
     3361 ttggactttc cagaagtgac attagttggg gtgttgaatg ctgatacctc cctgaattta
     3421 ccggattttc gttctagtga gcatacattc caattgctta cccaagtttc aggacgagca
     3481 gggcgagcgg aaaaagcagg cgaagtcgtg atccaaacat tcaatcctca acattacgcc
     3541 atagaattag ctaaaaaaca aaattatgag cagttttatc agcaggaaat gcatgtacgg
     3601 catcgtggag gctatcctcc ttattacttt actgtgaaaa taaccgccag ccatcctgaa
     3661 gaacaagtag cggcaaagaa aatctttcag attgccaatc agctaaaaga agtgttaagc
     3721 cctcaaagct tgctattagg gccaacgccc agcatgattt tgagagtgaa aaaccgatat
     3781 tattatcaac taatcatcaa atataaacat gaaccgaatc ttcctcatgt tttggatgaa
     3841 attttgaatg gaagccagaa agaacagcga caaggtcttt ttgtggcaat tgacaacgaa
     3901 ccattaaact ttatttaaga aagggccaaa ttatgcgcta tcctatattg atccacccta
     3961 atgataaatt aaaaagaact gctcagccaa tcgatgtaat cacggacgag acaatcgctt
     4021 tattagacaa tttatatgag acaatgattg cgaatgacgg aatagggatc gctgctcctc
     4081 aagtaggaca aaacaagaga attgctgtga tcgaagtaga tgaaggcgag aaatttgaac
     4141 tgattaaccc agaaatcatc gaagcaaaag gtgaaagcct tgacgtagaa ggttgtctca
     4201 gtattccgca tgtctatgga acggtcaagc gagcagatga agtgaccgtg cgttattatg
     4261 atcgagacgg agaagagata gaagtgacgg cttttggcta tttagcccgt gccttccagc
     4321 atgaaatcga tcacttagac ggtatcttgt tcattgagaa aatgatacag cagatcccgg
     4381 aagaagaact tgaagaatat atggaggaac atcttgatga ctaagctagt atttatgggc
     4441 acacctgctt tttctgtgcc gattcttgaa gggctgatag aatcaggtta cgagatccag
     4501 gcagtggtaa cacagcccga ccgtccagtt gggcggaaac gagtaattac gccgacaccg
     4561 gtaaaagaag cggctctgaa gcacggtatc cgtgtgctgc agccagagaa aatctccggt
     4621 tcgccagaaa tggaagaaat cattgaattg gtgcctgatg tgatcgtcac tgcggcattt
     4681 ggccaattct tgcctgaaaa gttattgcaa gtaccaaaat taggggcaat caatgtccat
     4741 gcttctttac ttcctaaata tcggggaggt gcgcctgttc attatgccat catgaatggg
     4801 gagaaagaaa ctggtgtaac gatcatggaa atgatcaaaa aaatggatgc aggcggaatc
     4861 tatgcgcaag aaagcatacc aatcactaaa caagatgatg tagggacgat gtttgaaaag
     4921 cttagccttt taggaagaaa gctattgcta gaaacattgc ccaatatttt ggatggacaa
     4981 aaaccagtac ctcaagacga gtcagaagca actttttcgc caaacatcac acgggaacaa
     5041 gaagcaatcg attggcataa aactgcagaa gaaattgaca accaagtacg cggaatgcgt
     5101 ccttggccaa ttgcattcac gacctatgag ggcatacgct ggaaattatt atcggttgaa
     5161 gtattggcag aaactacaga caaagcacct ggtacgatca tccggaaaga caaaaaaaat
     5221 ctatggattg cttgcggtaa acagaccgtc ttagccatca atgaattaca gccagctggt
     5281 aaaggaaaac aggccgtaca tgatttcctt aacggaagcg gtcagcaagt tcagattggt
     5341 cagcaggtga aataatgaaa aaaatcccta aaaaaatgaa aaaatcagta cgatatatgg
     5401 cattactgac attagagcga gtgaacaagg gtggcgccta ctcgaatctt ttgttgaatg
     5461 agatgatcaa acaaagcgag ctaaatcaaa aagatgtggg tttatttaca gaattgatct
     5521 atggtacgat tagccatcag cgactattgg aattttacgt tgcaccattg atcgctaaag
     5581 caaaaaaagt ggatgactgg gtcaagacgc ttctttatct ttctgtatac caattagaat
     5641 ttttagataa agtccctgca catgctattt taaacgaggc ggtcgaaatc gcaaaagtaa
     5701 aaggaaatcc tgggacaggg aaatttgtaa atggtgtctt gaggaattat cagcgtcaag
     5761 gagcaccaga tctgcaaggc attgctgatc ctatcgaaag actttctgtc aaaatcagcc
     5821 tgcctctatg gatgacgaaa cgactggtgg atcaaatcgg atacgaagaa actgaaaagc
     5881 tcggtttatc gctatatcag cctagccatg ctagtgcccg agtagataca cgccgacttt
     5941 ccagagatca ggccatcact gttttgcaag aagaagagat cacagctgaa aaaagccaag
     6001 tcagtccata cggtatagta gcgaaaaaag ggcatttagc ttctagctca ttgttccacg
     6061 atggcgtcat gacgatccaa gatgaaagtt cgatgcttgt agcgccgtct atgcaaatcg
     6121 agcctgaaca tcatgtctta gatgcctgtg cagcacccgg aggtaagacg acgcatattg
     6181 cttctttttt agatccgtca tgcggtggag aagtggtcgc tttagatgta cacgaacaca
     6241 aagtcaaact cattgaagat aatgcagcac gtctaggtgt ctcttctgct gtctacgctc
     6301 aaaagatgga tgctagagaa gtcagtaaac agttcgaagc agagcagttt gatcggattt
     6361 tagtagacgc gccttgttca ggtcttgggc tgcttcggcg aaaaccagat attcgttata
     6421 aaaaacagcc ggatgaatta gcgaatttac caaaaatcca attggaaatt ttagaaagct
     6481 gcgcaccaac tttaaagtct tccggtattc tgacttatag cacttgtacg atcttaaaag
     6541 aagaaaacca agacgttgtt tctgctttct tggaaagaca ccctgatttt gagaggattg
     6601 atgttttgac caatcctatg ctacaatcat caatcgaaga gaaaatgttg actttgtatc
     6661 cgcatcagtt ttacacagat ggatttttca tttgttgttt gcgcaaaaag taatgaggtg
     6721 aaaaaatgca gattgaatat caatcagatg taggaagacg acgtaacaca aatcaagact
     6781 atgccagtgt atttaccagc cgttcaggtc tcaagcttgc tgtattagca gacgggatgg
     6841 gtggtcatcg tgccggagac attgccagtc agatggcggt aacgaatcta ggcgaagctt
     6901 gggaaaaaca agaagctgtt gacgatgaaa aaatcgccca atggttcatt caatcgattc
     6961 aagaagaaaa tatgctgatt tatcagcgtg gacaagaaca gccggaatat aacggtatgg
     7021 gaacaacaat cgtagcggcc gctctgtcag atgactggtt cacgattgcc aatgttgggg
     7081 atagcagagc ttatttgatt cgtgaagata aaatcatgca attgacggag gatcattctt
     7141 tagtcaatga actagtcaaa tcaggagaaa tcagcgaaga aatggcagtg aaccatccaa
     7201 ggaaaaatat tttaacacgt tctgtcggca tgcctggaac agtcgaagta gatgtttcta
     7261 ctcatctttg gcaactaaaa gatcgactgc tgttatgttc agatggcttg acgaacatgc
     7321 tgtctgaaga agaaatagga acgatcatca atcaagaagg cccattgtct cataaagtaa
     7381 ctgagctgat tgatcgtgcc aatgaagcag gcggagcgga taatatcacc gttcttctta
     7441 tcgaatataa ggaggacagt gtatgatcga gttgggcaaa aaattaaatg gccgttatca
     7501 aatcactgga aatatcggta gcggtggtat ggcaaatgta tttttggcgc acgatttaat
     7561 cttggatcgt gatgtagcag ttaaagtctt acgatttgac tttcaaaatg accagactgc
     7621 gattcgacga tttcagagag aagctttagc agcaacagaa ctcgttcatc caaacattgt
     7681 tagtgtttac gatgttggtg aagaagacaa catgcagtat ctggtgatgg aatacgtcaa
     7741 aggaatggac ttgaaacgat atatccaaac acattatcct gttccttatg aaacagcagt
     7801 aaatattatg cagcagatcc tttctgctat ttctttagct cataaccatc aaatcatcca
     7861 ccgagatttg aaaccccaaa acgtactgat cgataatgaa ggtgttgtaa aaatcacgga
     7921 tttcgggatt gctatcgctt tatctgaaac atcgatcacg cagacgaata cgatgctggg
     7981 atctgttcat tatctgtccc ctgagcaggc cagaggaagt atggcaacga agcagtcaga
     8041 tatttatgct ttagggatca tcctttatga gatgttgacg ggtagcgtac cgtttgatgg
     8101 tgaatctgct gtaacaattg ctttaaaaca ttttcaagat gatcttccat ctataaaagc
     8161 acttgatcca aatgtgccac aagcactgga aaacgtgatt ttacgggcaa cggctaaaga
     8221 acctgcagac cgttataagt cagccgagga aatgtctgat gatctttcta cagtattatc
     8281 accagctcgt gcaaacgaag aaaaatggca gcctcatgtg atggataatg aaacaaaagt
     8341 tatcacaccc cttacggaag atgcaccaat gcctgattca ttcaaatcta tgcctctgcc
     8401 aaaagacaag ccagaaaacg aaaccttgcc agaggaggaa gaagttctgc ctgatcctaa
     8461 aaagaaagga cagaaaaaat ggtggctgat cctattagct attcttgctg ttttaggaat
     8521 cggaacagct gtattctttg cttctggcgg gcgaggagaa gttgttgttc ctgatgtttc
     8581 tgatctttct gaagcttctg ctagagaaac actcgcaaaa gcgaaattag aagtagcaac
     8641 aaaaacagaa gaaattgcag atgacaaaat cgaagaaggt aatgtagtga agacagaccc
     8701 ggcagcggga acgacagtca agcaaaaacg cgaagtcact ctgtatatta gtagcggcac
     8761 gaaaaaaatc aaattagatg attacagtgg taaaagttat gaagatgccg aagcaagttt
     8821 gaaagaatta gggttttctg ctgacttgat tcaaaaagaa gaggaattca gttcagaggt
     8881 agaaagcgga atgatcattt cgcaatctcc atcagaagat acagaagtcg atcctaaaac
     8941 agacacgatt actttcacag tcagcaaagg accagaaaca gtgactttga gtagtcatgt
     9001 aggagaaaac tacgaaactg ttcgtaattg gcttgttaca caaggattca atatcaataa
     9061 tattagtgct acttatgact atagcgacac tgtaccatca ggttcgatca tcagtcagga
     9121 tccagcctcg ggtgaagttg tagcagaaga aacttacatc aattttgtcg taagccaagg
     9181 aacagagcct aaattgaatg atatctccgg ctatacaaaa agcgaagcac aaagttattt
     9241 agctagtgtc ggtgcagaat atatcgggca tgagacttcc gaatattcaa acacggtgga
     9301 taaagataaa gtgattcgta cagtaccagg ggcaggaacg acaattacca aaggaatggt
     9361 tgtgaacgta atttactcta aaggaccaga tccagcgtct tctagttctg aaaaagactc
     9421 ttcagacagt tctagcagct caagtagctc cagtagcaca agcaactctt caaaagaaga
     9481 atcttccagc tccacaagtt catcagctag cacctcagaa agttcaaaat aagtgctgaa
     9541 taaaatatat cagaagggaa tgcgacattg atttgttgca ttctcttttt tgtgtttcta
     9601 tctcttttga tcaattttca agccatatac tttgagaagt ttgcatggaa taacacctac
     9661 tttcctcttc gtatggtaaa ataaacaaaa acggaggtgg cacttatcaa aggacaaatc
     9721 agaaaagcaa tcagcggttt ttactatgta tacgcaaacg gagagaccta tcaaacaaga
     9781 ggaagaggaa atttccggaa tcggaaaatc acgccgcttg tcggagatca ggtgatcttt
     9841 gagagtgaaa atcaaacaga cggctatctt ctggaaatct tgccgagaaa aaatcaatta
     9901 gttcgcccac cagtcacaaa tgttgatctt ggaatcattg tcacaagtat cgtagagcct
     9961 gcattttctt ataatctact tgaccgcttt ctagttacct tggaatacga gtcgatcgaa
    10021 ccgattattt ttttgacaaa gaccgacttg tcagacgacc cagaaaaaat cgaagagatc
    10081 aagcaaacct atactaaaat aggctatccg gtgattgtac ccaatcatac gggtgatacg
    10141 acagaactga tccgttactt cccagaacgg ctatcggtct ttatgggtca gtctggagca
    10201 ggaaaatcga cgctactgaa tcaaatatca ccggaactga atttagcaac aggagagatt
    10261 tctgatgcac ttggaagagg acggcataca acacgtcatg tggaactgat tcctatctat
    10321 ggcgggttag tagcagatac accaggattt agctcgattg actttttgac aattgaagca
    10381 ggagaactgc cgagacaatt tcctgaattt gtagaagctt ctgtccattg caaatttaga
    10441 gagtgcatgc atgctaaaga acctggctgc gaagtaaaac atagagtaga aacaggtggt
    10501 atcgcacaga cacgttacga caattatttg caattcttac aagaaatcga aaaaagaaaa
    10561 ccaatgtatg caaaaaaaga aggtaaacga aaataggagg aaacaagaat gaagatagca
    10621 ccatccattt tgagtgcaga ttttgccaat ttacaaagag acattgagtt agtggaaaaa
    10681 ggaggcgcag attacatcca cgtagatgta atggatggcc aatttgtccc aaatatcaca
    10741 ttagggccaa atattgttca ggcaatccgt cctgttacta aattaccgtt agacgtccat
    10801 ctgatgatcg ttgatccaga aaactacatt ccagcatttg caaaagctgg agcagatatc
    10861 attactgtcc acgtcgaagc aactcctcat attcatcggg cacttcaaat gacaaaaagc
    10921 ttaggagtta aagctggagt agttatcaat ccaggaacac cagtctccat gatcaaacat
    10981 gttttgcctt tggctgatca agtactagtc atgactgtca atcctgggtt cggcggacaa
    11041 agctttattg aagaaacagt agaaaaaatt acggaactcg ctgatctacg tagagagaac
    11101 aattggactt atgcaatcga agtagatggc ggaatcgttc cagaaacagc aaaaatctgt
    11161 aaagatgcag gggcggatgt cttcgttgca ggatcatata tctatggagc cgaaaatcca
    11221 gtcggacaaa tcgaacgatt aaaagaggca ttagactaaa tgaaaatttt attagctgct
    11281 ggaggtaatc cgcaaaactg gccgcagtct ctgctgtcca aatacgatgc ctatgtcggg
    11341 atagaccgtg gtgcgctgta cctgcttcaa gcaggctacc cagtagatct ggcagtgggc
    11401 gattttgatt cattgtcgaa cgaagagcag aaggaagtat ttgcaaaagc caaagagtat
    11461 acccgttccc ctgcagaaaa agacgataca gatacacagt taggtatctt aaaaacattt
    11521 gaacgttacc cgcaagcgga agtcactttg attggagcta cgggcggaag attggatcat
    11581 cttttagcca atctctggtt aggtatggaa cctcgcttca aaccctttgc ccatcagctt
    11641 attatcagag attgtcaaaa ttatttgtct tattatttgc ctggagagca tatagtaaga
    11701 cagataccag atatgaagta tttagcttat tgctgcttga ctcccgtctc gaatcttaca
    11761 ttaaaaggca gcaagtatgt attggaaaat aaagaagtag aatatccgac atcttatgca
    11821 agtaacgaat ttctttcaga taccgcagaa ttttcttttt cagatggtat gattgcagtt
    11881 attcaaagca aagattgatc cataaacaaa taaaaaaatt tgtctttcag gctaaaaatg
    11941 acagaatcta ttatttgcta aaaaaaagct taagaggagc aacttacctt ttgtttcacg
    12001 gcatttagtg ataaaattga acacaagagt ctaattaatt cgaggtgtct ttgtgaagaa
    12061 gttcaatcct aataaaaata ttattattac cttggttatt gttatcatcg tggtgacgat
    12121 actaagtgtg accgctgcgc agcgagcgaa tgaaggaaag cccaatttct tccaatccat
    12181 cgttaatgac agtgttgcaa tggttgataa aacaatctct gccccagtac ggtgggtacg
    12241 aaatggagta gattctgtcc ataatctttt ttcaacttat gccgaaaatg agcggctaaa
    12301 agaaaaaatc gatagctatg atgacgtttc acagcaaaac aagaattacg agagagaaat
    12361 cgaagcgttg aaaaaagaac ttgagttgaa tcagacgctg actagttacg aaaaagtaac
    12421 ggcaaatgtc attactcgtt cgcctgacag ttggcaggac atgctgatcg tagacaaggg
    12481 ttctaaagac ggtatcgaag caaatatggc agtcatgtcg caaaaaggat tgattggccg
    12541 agtgatcgag gtcaatacgg cttcgtctaa aatcgaatta ctgtcatcct ctaatgaaag
    12601 ctccaatcat tttccagtac gggtatcttc ggctaatggc gaagcgtttg gtttgcttaa
    12661 aaactatgat gaaaagctcc atgccttagt ggtgacccaa ttaactggtg atacggatat
    12721 caaagaaggg gatgttgtcc agacatccgg tcttggaggg aattctccag ctaacttgcc
    12781 gatcggtacg gttattaaaa cgaaaccaga tagttatggg ctggatcggg aagtttatgt
    12841 gaaaccttat gcagaaatgt atgacgtgtc agttgtgacg attgtccaac ggctagcgga
    12901 ggattagtcc atgttgaaga aagaaacaat gaagtactat ctgccaatcg ttttgttctt
    12961 tttgatgttg atagatggtc atttaacaag aatgctaggg gagtggtcga aaggcaccta
    13021 tatgtcaaat gcccactttc tgatattggc attattatgt tgcagtatgg cgtttgaaaa
    13081 acgttattta ctgattacca cgattgttct cggggctatc tatgacgctt actatattgg
    13141 cgttatcggt atctatgcag tagctctccc tttaattgta tggttgatgt atgtaatgaa
    13201 agacgttatc catgtcaaca tctttactga atttttcagt atgatcatct ttgtcacggg
    13261 ttatgaattg tttacgatgg tggtccagtt gatttttaaa ttagcagtag taaataacac
    13321 gtattttatt acaaggtttt taggacctac actgctgttg aacatgatta tatttgtatt
    13381 attcattttt ccctttaaga aattattcag tgatgaataa tttctttttt tatttttagg
    13441 tcgaaagcga aaaagaatcg ttgttatctt aagaaatgct agacttaacg cggctttttc
    13501 atgatcattt tctgaaacga acagttttgt catttttaaa agttgttttg aaacattttt
    13561 gtaacataac tattatatcg ttgacacact gctatggtac aatttttata tcgttaagaa
    13621 agacttaaat atatttagat atttattaaa ttaagccagt cggaggaatg aagagtgaaa
    13681 aagagtttaa tatcagcagt aatggtatgt tcaatgacct tgactgccgt agcatcaccg
    13741 atcgctgccg cggcggacga ttttgattct cagatacaac agcaagatca aaagattgca
    13801 gacttgaaaa atcaacaagc agatgcacaa tcacaaatcg atgccttaga aagccaagtt
    13861 tctgaaatca acacacaagc acaagaccta ttagcaaaac aagatacatt gcgtcaagaa
    13921 tctgcacaat tagtaaaaga cattgcagat ttacaagaac gtattgaaaa acgtgaagat
    13981 acaatccaaa aacaagcacg cgaagcacaa gtaagcaaca caagctcaaa ctacatcgat
    14041 gctgtattga atgctgattc attagcagat gctattggac gcgttcaagc aatgacaacg
    14101 atggtaaaag caaacaacga cttgatggaa caacaaaaac aagataaaaa agctgtagaa
    14161 gacaaaaaag ctgaaaacga tgctaaacta aaagaattag ctgaaaacca agctgctttg
    14221 gaatctcaaa aaggcgatct tttatctaaa caagctgatt tgaacgtact gaaaacttca
    14281 ttagctgctg aacaagcaac tgctgaagac aagaaagctg acttgaaccg tcaaaaagca
    14341 gaagctgaag cagagcaagc tcgtattcgt gaacaacaac gtctagcaga acaagctcgt
    14401 caacaagctg cacaagaaaa agctgaaaaa gaagcacgcg aacaagcaga ggctgaagca
    14461 caagctactc aagcttcatc tactgcacaa agctcagcaa cagaagaatc atcagctaca
    14521 caatcttcaa tgactgaaga atcatcatca gctacacaat cttcagcaac agaagaatca
    14581 acaacacctg aatcttcaac agaagaatca acagcgcctg aatcttcagc aacagaagaa
    14641 tcaacaacag cgcctgaatc ttcagcaaca gaagaatcaa caacagtgcc tgaatcttca
    14701 gcaacagaag aatcaacaac agtgcctgaa tcttcaacaa cagaagaatc aacaacacct
    14761 gcgcctacaa caccatcaac agatcaaagt gttgatacag gaaacggcac aggaagtagt
    14821 actccggctc caacgccaac accaacacct gaacaaccaa aacctgtaac acctgctcca
    14881 gctccttctg gaagtgtgaa tggtgcagca atcgtagcag aagcttacaa atatattggt
    14941 actccatatg tttggggcgg taaagatcca agtggctttg actgctcagg gttcacacgc
    15001 tatgtttaca tgcaagtaac tggtcgtgac atcggtggtt ggacagttcc tcaagaatca
    15061 gctggaacaa aaatttcagt ttctcaagca aaagctggag acttgttatt ctgggggtca
    15121 caaggcggaa cttaccacgt agcgattgct ttaggcggag gacaatatat ccatgctcct
    15181 caaccaggcg aaagcgtaaa agttggttca gttcaatggt ttgcccctga ctttgctgtc
    15241 agcatgtaag aatgattaat caaaaa
//
LOCUS       DAPBBR010000059        15244 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPBBR010000059 DAPBBR010000000
VERSION     DAPBBR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.062"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            168..362
                     /locus_tag="RD488_002168"
     CDS             168..362
                     /locus_tag="RD488_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658227.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="RD488_002169"
     CDS             631..930
                     /locus_tag="RD488_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658228.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="RD488_002170"
     CDS             complement(1027..1461)
                     /locus_tag="RD488_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658229.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVHWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="RD488_002171"
     CDS             complement(1693..2403)
                     /locus_tag="RD488_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7658230.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="RD488_002172"
     CDS             complement(2393..3253)
                     /locus_tag="RD488_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDT7658231.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="RD488_002173"
     CDS             complement(3258..3896)
                     /locus_tag="RD488_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDT7658232.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="RD488_002174"
     CDS             complement(3911..4210)
                     /locus_tag="RD488_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7658233.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="RD488_002175"
     CDS             complement(4253..5737)
                     /locus_tag="RD488_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7658234.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="RD488_002176"
     CDS             complement(5757..6218)
                     /locus_tag="RD488_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7658235.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREATAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="RD488_002177"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="RD488_002177"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDT7658236.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="RD488_002178"
     CDS             7521..8291
                     /locus_tag="RD488_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7658237.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="RD488_002179"
     CDS             complement(8564..9391)
                     /locus_tag="RD488_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658238.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="RD488_002180"
     CDS             9959..11194
                     /locus_tag="RD488_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7658239.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="RD488_002181"
     CDS             complement(12193..12453)
                     /locus_tag="RD488_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7658240.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVTHLNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="RD488_002182"
     CDS             complement(12480..13781)
                     /locus_tag="RD488_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658241.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="RD488_002183"
     CDS             complement(14073..14531)
                     /locus_tag="RD488_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7658242.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..>15244)
                     /locus_tag="RD488_002184"
     CDS             complement(14544..>15244)
                     /locus_tag="RD488_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HDT7658243.1"
                     /translation="KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITK
                     NFPSNIPNNYLEYYLYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVL
                     NFNFGEHGQYIVDIAISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEP
                     ITLRKPISDFHKGLMEAQVAVEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILD
                     EMIKVNKKYWPALK"
BASE COUNT         4876 a         3104 c         2366 g         4898 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa tgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgcccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatacttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcggtagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attataaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcaaatgcgt
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacgac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttat
//
LOCUS       DAPBBR010000060        14416 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPBBR010000060 DAPBBR010000000
VERSION     DAPBBR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.063"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(451..1761)
                     /locus_tag="RD488_002185"
     CDS             complement(451..1761)
                     /locus_tag="RD488_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7658244.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="RD488_002186"
     CDS             complement(1773..3191)
                     /locus_tag="RD488_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7658245.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="RD488_002187"
     CDS             complement(3431..4999)
                     /locus_tag="RD488_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7658246.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="RD488_002188"
     CDS             complement(5003..5413)
                     /locus_tag="RD488_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDT7658247.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="RD488_002189"
     CDS             complement(5410..6333)
                     /locus_tag="RD488_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HDT7658248.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="RD488_002190"
     CDS             complement(6330..7208)
                     /locus_tag="RD488_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HDT7658249.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="RD488_002191"
     CDS             complement(7195..8532)
                     /locus_tag="RD488_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7658250.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="RD488_002192"
     CDS             complement(8535..9638)
                     /locus_tag="RD488_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7658251.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="RD488_002193"
     CDS             complement(9712..11220)
                     /locus_tag="RD488_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7658252.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="RD488_002194"
     CDS             complement(11186..11878)
                     /locus_tag="RD488_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7658253.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="RD488_002195"
     CDS             complement(11900..12874)
                     /locus_tag="RD488_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7658254.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="RD488_002196"
     CDS             13174..14046
                     /locus_tag="RD488_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7658255.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
BASE COUNT         4253 a         3042 c         2380 g         4741 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaag ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaa
//
LOCUS       DAPBBR010000061        14363 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPBBR010000061 DAPBBR010000000
VERSION     DAPBBR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.064"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="RD488_002197"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="RD488_002197"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDT7658256.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="RD488_002198"
     CDS             complement(2424..2675)
                     /locus_tag="RD488_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HDT7658257.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="RD488_002199"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="RD488_002199"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDT7658258.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="RD488_002200"
     CDS             3624..3842
                     /locus_tag="RD488_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658259.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="RD488_002201"
     CDS             complement(4130..4642)
                     /locus_tag="RD488_002201"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDT7658260.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="RD488_002202"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="RD488_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDT7658261.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="RD488_002203"
     CDS             complement(7095..7538)
                     /locus_tag="RD488_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HDT7658262.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="RD488_002204"
     CDS             complement(7539..8327)
                     /locus_tag="RD488_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7658263.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /locus_tag="RD488_002205"
     CDS             complement(8324..9265)
                     /locus_tag="RD488_002205"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDT7658264.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="RD488_002206"
     CDS             complement(9442..10029)
                     /locus_tag="RD488_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HDT7658265.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="RD488_002207"
     CDS             complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="RD488_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDT7658266.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="RD488_002208"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="RD488_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7658267.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="RD488_002209"
     CDS             complement(12946..13881)
                     /locus_tag="RD488_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7658268.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14067..>14363
                     /locus_tag="RD488_002210"
     CDS             14067..>14363
                     /locus_tag="RD488_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7658269.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         4014 a         3194 c         2529 g         4626 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataacc cgcgaattgt
    13981 aaaattaagt tagaaaaata aaaaggcatt tatggtacac tcaaattgta tttccgacga
    14041 aagaaaacaa aggagtgtaa ccataaatga cctacaaaca tcttaccata gacgaactga
    14101 caatgataga atcatattat cttcaacata ataagccggt tgaaatcgct aaccgaatgg
    14161 gacgtgctat acaaactatt tataatgtag tcaataagtt caagcaaggc aagactgctc
    14221 ttgattattg gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat
    14281 tacctgctca tgaagtagat tacattaaag agaaagtcac tcttggttgg acgcctgacg
    14341 tcattatcgg gcgaaaagaa agg
//
LOCUS       DAPBBR010000062        14180 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPBBR010000062 DAPBBR010000000
VERSION     DAPBBR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.065"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(45..965)
                     /locus_tag="RD488_002211"
     CDS             complement(45..965)
                     /locus_tag="RD488_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7658270.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            1152..1643
                     /locus_tag="RD488_002212"
     CDS             1152..1643
                     /locus_tag="RD488_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HDT7658271.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(1667..4042)
                     /locus_tag="RD488_002213"
     CDS             complement(1667..4042)
                     /locus_tag="RD488_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDT7658272.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            4368..4994
                     /locus_tag="RD488_002214"
     CDS             4368..4994
                     /locus_tag="RD488_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7658273.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            5017..5721
                     /locus_tag="RD488_002215"
     CDS             5017..5721
                     /locus_tag="RD488_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7658274.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            5913..6746
                     /locus_tag="RD488_002216"
     CDS             5913..6746
                     /locus_tag="RD488_002216"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDT7658275.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            6943..8871
                     /locus_tag="RD488_002217"
     CDS             6943..8871
                     /locus_tag="RD488_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7658276.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            9009..9464
                     /locus_tag="RD488_002218"
     CDS             9009..9464
                     /locus_tag="RD488_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDT7658277.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            9934..10203
                     /locus_tag="RD488_002219"
     CDS             9934..10203
                     /locus_tag="RD488_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658278.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            10603..10857
                     /locus_tag="RD488_002220"
     CDS             10603..10857
                     /locus_tag="RD488_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDT7658279.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(10946..11992)
                     /gene="holA"
                     /locus_tag="RD488_002221"
     CDS             complement(10946..11992)
                     /gene="holA"
                     /locus_tag="RD488_002221"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDT7658280.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(12030..14120)
                     /locus_tag="RD488_002222"
     CDS             complement(12030..14120)
                     /locus_tag="RD488_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HDT7658281.1"
                     /translation="MTVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTMEGRL
                     SENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAYFRN
                     HRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGYKDA
                     GFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTICYV
                     SIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGGQLS
                     FFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPVFKF
                     LFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGMYIF
                     GLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSPFRK
                     ETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDHVGE
                     LPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLYVLT
                     PFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHHGSR
                     TSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITYRWH
                     PVFHPHGLVETMID"
BASE COUNT         4404 a         2711 c         2534 g         4531 t
ORIGIN      
        1 ttagatgtaa tagattaaat ttattctaaa ataaacctga ttcctcattt tttttgtgaa
       61 cgatttttta tttctggcaa tacgccagtt gttcgataca ttttttgttc gttttcattt
      121 gcaaaccggc caaatactga atgagttggt aaaatattga taaatgcatc gtcgtcgatt
      181 tcatgaacga tctgatcaag atcatacatt tcgtagcggg tgatgaccat catgatcatg
      241 ttcccttgtt tttttgaata gccaccgaca gacggcagta atgtcattcc acgtaccatc
      301 cgttttgcta gttcttctgt tacctcttct ggcttgacgg taacgatcat tgctgttact
      361 ttttgatgac tcgtgtggat ggcatcaatt acttgagtca ttgcataaat ggaaataatc
      421 gtatacaagg cactttccca gttaaagaag aagcctgcga tgactacaat gataccattt
      481 agaatcagca tgtagtttcc gactgttttt ccagttgttt gtgaaagtac aagagagatg
      541 atatccatcc caccagttgt aaagcccatt tttaaagata atcctacgcc aagacctaat
      601 aaaacaccgc ctactagggc attcatcaaa atattatcag tgatctgtcc gactggaagc
      661 agcatcgtca tcaccgatac acatacaaca ttcacaaaac taaggatcgt tgctcgtttt
      721 cctactttga gaaaccctaa tacaaacaca gggatattca aaagaaaaat aaatgttcct
      781 gtgtctatct tgatatgaaa ccattcatat aaaagcgagg aaatgatttg agcgatccca
      841 ttcatccctg cagaaaagac attggctgga atcaaaaaat aatttaaagc gaccgcagcg
      901 gtcaatccgg ttatcaaaat aaccactatt ttctttaatc tttcattttt atgatacgca
      961 gtcataattt tactcacaag cacctctccc ctactttggt attccaaatg taagaataac
     1021 agtttatcta ttaaaataaa atacttcgaa ctcaaatgag aagaatttta gcaaacaggt
     1081 aagaatctgc cctaatccta tgataagata gatgtatggt aaatatttat atgtatatca
     1141 ggagggttcc tatggcaaaa gatgctagct tcgacattgt atcagaagtc aatacagaag
     1201 aagtaaaaaa tgcgattcag caaacaacaa aagaattgtc caatcgcttt gacttcaagg
     1261 attctacagt agaaatcaaa ttagagaaca gcaatctagt tgtattgagc gatgatgatt
     1321 tcaaaatcga acagatcaaa gatgtattat ttggtaagct gatcaaaaga aatgtgccaa
     1381 tcaaaaatat ccatttttcc gaatcagaac acgctctagg tggcaaagct cgacaaactg
     1441 ccgatttggt caacggaatc gatcgtgaaa acgcgaagaa aatcactaca gctatcaaaa
     1501 atgaaaaact gaaagtaaaa gcacaaatcc aagaagatca gattagagtg acaggtaaga
     1561 accgtgatga tctacaagct gtgattgctt tattacgtaa acttgactta ccaatcgagt
     1621 tgcaattcac taactatcgt taatcaaaaa acgaggctga cgtctgtcat tcctcgtttt
     1681 tttgatttac tgcttctttt gataaccaaa aacgctgtat tccttcttcc aattccccaa
     1741 cacttcgtac ttctcttgct gtttgccaat gttgtgggaa taaacgtcga taagaaaaac
     1801 tagaaaatcg ttgatctgcc aatacaacga ttccttgatc cgccatgcca cgaatcactc
     1861 gaccaccagc ttgcaagact ttgttcattc caggaagctg ataagcgtaa gcaaatccaa
     1921 ggtgttcctt ctcatcataa tatgatttga tcagttcctg ctcatgattc atctgcggca
     1981 aacctacacc tacgatcata ctgccgatca atcggtcccc tctcaaatcg attccttctg
     2041 aaaaaatccc gccaagtacg caaaatccaa tcaatgtttc agcgggattt gtttgaaatt
     2101 ttgttaaaaa tcgttcgcgt tcttcctcat tcatgtccgt ttcttggatt agcacattgc
     2161 tgtcgggata ttgctgtctg aatgcttcca ccgcaagatc taaatattga taagaaggaa
     2221 agaaaacgaa ataattcccg acctttccat cagcaaaagc atgaatcgtc tctactaatt
     2281 ttgccagact gtgttccctt tttcgataag tcgtctctag gtaatttgcg atgaaaactt
     2341 gctggtttcc ttctgggaaa ggactcggca gtttgtaagc cagacttttt tgtcccccca
     2401 gtgtttcctg ataataagag agtggtgaaa aactagcaga aaaaagaata ctgctttttc
     2461 ctttatccaa cgactgctca agaaacaagc ttggatcaat acaaaactct tttactatca
     2521 gatcgcgata cgttttttcg actgttgttt cgtagtgatc atcataaaat tcactgacct
     2581 tcaaaaaatg aagcaaatca aaataataag gaagcaattg ttcttgtgat gggtgctcag
     2641 gaaattctgc cagccattct ttaatttttt cgcttaattg ataacctgcc tttactaaag
     2701 attcagccgg tgctttttga tgatgataat cccaatgatc ttcttttgct atttctcgga
     2761 tcgaatcaaa ttcttttaat agtttgttga aacggcgatg aagttttttg aattcctttg
     2821 gtatagcttc cttacttcgt ttcgtttttt cataagatag ttctgccgaa tacatctctc
     2881 gggaacgatt caccaaatta tgtgcttcgt caatcaaaaa cagatagtcc tcgttttttt
     2941 catcttcaaa aaaacgtctt aaataaacag ttggatcaaa taaataattg taatccccaa
     3001 tgattacgtc acaccagata ctgacatcta atgatagttc gaaaggacaa agtgtatgct
     3061 ttcttgcata agtttcgatg acttcacgag tgatctgatt ctcatgattc aaaagatccc
     3121 ataaaccttc attaatccga ttgtaataac cattggcata tgggcactga tctggattac
     3181 aggtcgtctc atctaaaaag cagatcttgt ctttcgccgt caaagtgaca ctttttactt
     3241 cagctcctgt atcttttaat gctgtcatag catcttcagc tacttgtcta gttattgttt
     3301 tagccgttag ataaaagatc ttttctccct cttcttcccc tacagctttc aaagcgggga
     3361 ataacgtaga gattgttttt cctgttccgg taggtgcttc tacaaacaat ttctgtttcg
     3421 tacggatcgt tttataagca gctaccgcta gttcacgctg acctttccta tactcatcat
     3481 gggggaattt caaagccatc aaagaggcat tgcgtacagt gcgccagttt tcttgaaaaa
     3541 caagccattc tttataatct tcagtcagct ttttaaaaaa agtttctaac tgctctcttg
     3601 tctgatgttc aacctttctc gtgatcactt cttctgccgt ctggaagtaa gtcaattgca
     3661 gatttatttc ttgtaaatca tgttcttgac tatagatata ggcatacacc cttgcttgat
     3721 gaaagaaaag ttccacttgt tctggttcta aatcttcaaa tcgtggttcg gaggttttga
     3781 tttcatctat ataataaata ccgtctcttt tgaaaatacc gtctgcacgg ccttcaacga
     3841 tcaggtaata ttcatctaat tgaactgttg tttttaaaaa gacttctttt tcatagtttt
     3901 ctcccgcatc tttttggagc ttgcggtgga ttctcgctcc ttctaatgca gtatggttac
     3961 tttttttacg attgtcgata cttccacgtc gcaaaataaa ttctactaag tgccgcacag
     4021 atatttttga ctgtttgatc atttccacca cctctttctc tctaagatta cctgaaaaaa
     4081 cctagtttag caaaaagagc tctctttcca aacataaaaa aacaccctgc tgattaggca
     4141 gggatatagg atatagaatt tggatttttg gatgaatcta atgtaacaag gacatattaa
     4201 aatgctatga aaacttactt tccttctctt tagaatatcc aaatactttt catatagtct
     4261 gataattcag ataagtaaag agaaataagt acctgttttt gtttcctagc aatgaatgcg
     4321 ttatactaat ggatgaaaga agttttggct atcaaggagg aatgcacatg catatcgaaa
     4381 gattaaaaac aggaatgatt gaagaaaact gttatttggt ctacaacgaa gaagcacttt
     4441 tgatcattga ccctggagaa gatgcggaac gaatcaaaca agaaatcaaa aaaacaaacc
     4501 aacagccggt agcgattttg cttacccata ctcactacga tcatatcggt gcagtggaac
     4561 ctttacgcgc gtattatcaa atcccagttt atgtcagccc actagagcaa aaatggctag
     4621 gtgatccgat tttgaatctt tctggactcg gtagacatga tgatattgct gatgttattg
     4681 tctcgcctgc agaatatgaa tttgaaatga aaacttatac tttaggaaac atgtcttttc
     4741 gcgtcgtccc taccccaggg cattctatag gaagcgtcag ctttattttt gatgattttg
     4801 tcgtttctgg cgacgccctg tttagaggaa gtatcggtag aaccgatctg tatacaggga
     4861 atttagaaca attacttcat agtattcgga cccagctgtt tgtattacct gatgaatttg
     4921 cagtctatcc aggacatggc gatgcaacga cgattgaaca ggaaaaaagg acaaatcctt
     4981 ttttcaatcg ttaaaacgac ttaggaggag aataaaatga cagaaactac actttatatc
     5041 gtacgacacg gaaaaacgat gttcaataca attgaacgag tacaaggctg gtgtgataca
     5101 cccctcacaa agcaaggaca agaaggcatt cattatttag gtcgcgggtt aaaaaatgtc
     5161 gacttttcat ttgcttattc tagtgacagt ggtcgtgcaa tcgaaactgc ccgtattatt
     5221 ctaggagaac attctaaggg aaaagaaatt ccttatttta ttgaaaaaag gattagagaa
     5281 tggtgtttcg ggtctcttga aggtggatat gacatggaaa tgtggggtgt gatccctcgt
     5341 gtattgaatt ttaaaacata tgatgaaatg tttaccacag aagtttcttt tgaacaaatt
     5401 gctaatgctg tatacaactt agataccgct gggtgggcgg aaacttatga aacattgcga
     5461 gaccgtgtat ggacaggatt tgaagatatc gcccatcact gcgaaaaaaa tggtggtgga
     5521 aatgttttag tcgtatctca tggtttgacg atcgcctttt tgcttaatct gatcgatcct
     5581 aaacagcctg ttcgtgctgg gcttttaaat ggcagcgtaa caaaggtcac ttatgcaaac
     5641 ggtcgatttt ctatccacgg catcaatgat acgtcttata tcgataacgg gaaaacacat
     5701 agtcgcgact cgtttctata atggggatat tttaattttt accagagaat cataaaaggc
     5761 aaagtctgaa cgagggcttt gtcttctttt ttctcttcgt gtacttatct gctttatttc
     5821 tcaagttttt cttaatatta aaaaacagat tgggtttctc aaaaaataac ggtatactat
     5881 aagatgtatc ttaattggga aggaaggaat ttatgttttt tgcaaatatt atcaaagcag
     5941 tgattctcgg tattattgaa ggaataacgg aatgggtgcc catcagtagt actggtcatt
     6001 tgatcctagc agatgaattc atcaaactgg atgccagttc acaatttatg tcgatgttca
     6061 atgtcgttat ccaattaggg gcgatcttgg ctgtcgtcgt tctttatttt cacaagttaa
     6121 acccattttc tccaagtaaa tcaacggtag aaaaaaaaga tacgtggaca ctttggttta
     6181 aagtgatcgt tgcttgcata ccagccatca tcattggttt gcctttggat gattggttag
     6241 aagcaaattt ccacaagttc ttaccagttg ccattgtttt gatcgtttac ggtattgcct
     6301 ttattattgt cgaaaaacgc aacaaaaaca aaacacctcg ttggacttct ctgaatgact
     6361 ttacgtacca agcagctctt cttgttgggt tattccaagt cttggcactt gttcccggaa
     6421 catcccgttc tggcgcaacg atcctaggat ctatcttgat tggtgcttcg cgttttgtcg
     6481 ctacagagtt ttcatttttc ttagggattc ctgtcatgtt tggcgcaagc ggcttgaaga
     6541 tcgtcaaata tttagctgaa gggaattcat tcaaaatgga agaaactgtt gttcttcttg
     6601 taggaacatt cgtatctttt gtggtttccg tcttagctat caaattctta ctaagctatt
     6661 tgaagaaaaa cgactttacc gcttttggct ggtatcgtat tatccttggt atcattttga
     6721 ttggttattg gtttattgca atgtagaaaa aaccagaaca cttctcttat ttgagaaatg
     6781 ttctggtttt ttattttctt taataataat cattataaat aataaaaaca acatcaagct
     6841 taatcaccaa atgataacca ttatcgttct catttagctg ttattattat caattacatt
     6901 tttattatgc tatccttgtt ttgacaagga ggtctaataa cgatgactaa tcagaaaaaa
     6961 gcttttgcag caacaatcgg ctgcctttta tttatgatct tcggttttat cttcgaccga
     7021 ttctctctta ccatcacccc acttttttat atcagtgcca ttatcatcgg tggatataaa
     7081 caaacatcgg aaggcttgaa agaattgtgg aatgatcgga cactgaatgt ggatttattg
     7141 atggctttag ctgctattgg tgcctgtttg atcggtaatt actttgaagg agcaatgttg
     7201 acattcatct tttgtttaag cggtgcatta gaggaataca caactaataa aagtcaaaaa
     7261 gaaattactg ctttgatgaa tcttcaacca caaaaagccc aattattaaa agaaaatgga
     7321 caaatgcaag aagtagatgt ttctcaacta aaggtggata acttggtatt tgtcgctaaa
     7381 ggagcagctg ttccgataga tggcttttta gaaagcacac aggcaacgat cgatgagtct
     7441 gcattaagcg gtgaatctgt gcctgtagaa aaatatttag gcgatgagat gtatgcagga
     7501 acgctgaatc aaggaaatcc catcacgatt cgagtaacaa aaacgagttc cgaaactgtc
     7561 tttgctaaga ttatccaatt agtagaagaa gcgcagaata cgccaactca aacagcttca
     7621 tttatcgaac gaatcgaaaa taattatgta aaattgattt tgcttgctgt tcctctaatg
     7681 atccttctcc cccacttttt cctaggttgg agttgggatg aaagctttta tcgaggaatg
     7741 gtattattag ttgtggcttc tccttgtgcg cttgtcgcat ctgctacacc agcttctcta
     7801 gctgctcttt caaattctgc aaaaaatggg attttaatca aaggcggtat ccatttagaa
     7861 aagctttctg aattaaaagc gattgccttt gataaaacag gaacgctcac taaaggaaaa
     7921 ccagttgtaa ctgacagctt tttctttgat gaaaaggatt tggcacaaca acttcttgtt
     7981 gctatggaac aaaaaacgac gcatccactt gctcatgcga ttttgcaata tttcgattgc
     8041 acaatacctg aagaaatcca atacttacca atagaagaaa ttactggttt tggattacaa
     8101 actacctatt taggtgcgca atggaaagtt ggcaagcacg catatgatcc tgagacgatg
     8161 ataatcagca aagagattgc ggaaatgatc gaacgtttgg aaaatcaagg caaaaccgtg
     8221 atttatcttt ctaaagatca gcagttaatt gctgttttag gtctgctaga tattccaaaa
     8281 gcaaataccc aacaagtaat ttcctacttt aaatcccaaa acatccatac aagtatgata
     8341 accggcgacc attctggcac agcaaaggcc attgctgaac aagtagggat tgaacattac
     8401 tatgcaagct gtactccgga agaaaaaaca caactagtca aaaaagagaa tgaactttac
     8461 caagtaaatg cgatggttgg tgatggagtc aatgatgcgc ctgctttagc agccgcttct
     8521 ttaggtgtcg ctatggggca agggacagat gccgctatgg atatcgcaga catcgtctta
     8581 atgaaaagcg acttaaataa atttgtctac agtcatcggc tatctttaaa aatgcggcgg
     8641 atcatcaaac aaaatattat tttttcgatt cttgttattc tcttgttgat tgcttctaac
     8701 ttcctgcaat ttttaaatct acctcttgga gttgtaggac acgaaggaag cacaatattg
     8761 gttattctga atggcttgcg tttactaaga cctttacctg atctttctga ttcttcaaaa
     8821 aaatgtaagt cttgtccact atacaaagcg cggctgtctt ctgtcaaata agcaaagtgt
     8881 ttttttatga ttttgtttat tttatgaaaa aaacagctta tgaataggtc ttgaaggatg
     8941 aattcctact tttgtaactt tctaaaaaca tgttatgatt gtttcgaaga aagtgaggaa
     9001 tatatttcat ggaaagttgg ctttttttag gaattatttt acttgtagca attttagcta
     9061 aaaatcaaag tctgatgata gcggcagctt ttgttttgat tatgaagctc ataccagcct
     9121 cccgttcctt tttcccttgg cttcaaggca aaggaatcaa tattggggtg acgatcatca
     9181 cagcggctat tctaatccct atcgcaacag gagaaatcgg tctacgtgat ctattagaag
     9241 cctttaaatc ccctattggc tgggtagctg ttttttgcgg tgggctagtg gctgtcttat
     9301 cttccaaggg tgtaggattg attgcttctg atccacaaat cactgttgca cttgttttcg
     9361 gcacgatttt aggtgttgtc ttcttaagag gaatcgccgc cggaccggtc attgcttctg
     9421 gtatcactta ctgtatctta caagtatttg ctttaggaaa atagaacaaa ttttgtctat
     9481 tttaggagat tcttaacacc cccaatttac tgatccgtga tatactgaca acgaggtgat
     9541 acaatgttcg aaaaattaaa gtatttcata ggaacaatcg gctggtttct tctagcggta
     9601 cttttgattc tgggcttagc ttatctatta tttcctgatt tgatacaaaa tgtgtttgat
     9661 actgcttttt gattgaccta ttaaaacgat ataggggatg ctcctgcgat gcaggggctt
     9721 tttttaatca atgttttgta ataatttagg ccgtgccaat gagacttcct atagaattcg
     9781 atgctctttt ttctttttgg ctcttctgct cttttttgtt atactagatt acagtggaca
     9841 aaagaaagaa tgatcgcatc cacttcaacg aatatcaaaa tggaagaatt agtgcctgtt
     9901 ttcaggttac tttgaaaaga aaggaagacg cttgtggaaa cttttgaagg tcttttaatt
     9961 gatacgtacg ttttacaaga acagccaatg atgctgactg ggatcaactt gcagcttgag
    10021 gaccgtgtga tcaatggcct gcttaaagat cgctatttgg caaaatatat cttacgtttg
    10081 cccctaaata aatatgtgct ggaagtaagt ggcaaatgga accgtcggaa ccagttggtc
    10141 ataaaaaaaa tgttgataaa aaatatcgat gaatacatta aaataatcgg tacaccagaa
    10201 tagcctttac tgatcaaagg atactggtta taaaataact gcagtttctt aatagaaaaa
    10261 caaagaacaa cagggaatcg tatccctttt caaaaaaaac tttgcaaacg gttctctttg
    10321 ttatataata acttagtacc aaacattccc attcaaactt tgtttaaata gataaataaa
    10381 aatctagttt ggtttgacgc tattgcctcc cacaatagcg tctttttgat ttttttcagc
    10441 ttgtactatc cgtttttact gaaaaaaaat cctaataaaa gactgttaag gaaaaaaact
    10501 tgtcatgttc atattgcaaa gcacgctgcc tttaggtata ataatgaatg ttgaattatg
    10561 cggtaacacg cgtaagaact taagttatcg gaggtgaaac taatgccaaa cattgaatct
    10621 gcaatcaaac gtgttcgtac aagcgaaaac gctaatgtga aaaattcatc tcaaacaagc
    10681 gctatgcgta ctgcaatcaa aaaatttgaa gatgctgtag cttcaggtgc tgacaacgta
    10741 gatgcgttat ataaagaagc tgttaaagct attgatatgg ctgaatcaaa aggtctaatc
    10801 cacaaaaaca aagctaaccg cgacaaatct cgtttaagca aaaaaatcgc taaataaaag
    10861 aatcggcttc ggccgatttt tttatttgtc aaaaaaagga caaaaacaaa cgaccttccc
    10921 gcatgctttg ccctcgtctt tcttcttatc gatttcttaa caactgccct gtgcgcaaaa
    10981 cgaatagttg aaaacttaat tctttttcga tttgtcccgt tttgatttga taatccatct
    11041 caactaattg atcaaacaac tgtaccagca aatgttcatc gaattttttt acttcctgca
    11101 tggcaagttt tacacgatat ggatggattt tcaatgtttc agcaatattt gcctgctgat
    11161 aaccaatctt tacaagaaat tttgtctgta aaaataaacg taattgagaa agcaaaatcg
    11221 cattaatttt gattgtttct tccccttgca taactaaatc ttcgtataaa cgcaaagctt
    11281 gttccgtctt cccttttaaa atatattggg tcatgtcaaa aatattatgt tctaacgttt
    11341 taggaactaa ttcttctact tctcttaccg tgatttgctg ttgattttgt ccataaagga
    11401 ccaatttctg taactctctc atcattttgg ataaatctaa gtcggtcaac ctcaagaata
    11461 aatcaattgc acttcgttcc attttgattg aggaattctc taaggtattc atcagatatt
    11521 gacgtacttc tttttcattc aactgttgga cattgatgat aattgctgtt tttttcaatt
    11581 gtttcgttac ttttttccgt tcatccaact tttcatatgg cgcaaagaat actaatacag
    11641 tcgattctaa tggttctttc aaataagccg tcaataaatc agtattttgt tcgattccat
    11701 tgtttacttt ttcacctgtt aaaaaataag gattctctac gaatactaac cgttgatctc
    11761 cgaaaaacgg caacgtctct gcttcagcta ctacctcatc taaacttgca ttttccatgt
    11821 caaaacttaa aaaatttaag tcatcttcgc cctctaattg gatttttttg acaatttctg
    11881 tccgaacttg atcttggaga aacttttctg ttcctaaaat caagtaacaa gatgcaagtt
    11941 tttctttacg tattttttgt aactctgctt gtatactcaa attactcacc actttcaaaa
    12001 attatcctac catgagcaga tgagaattac tagtctatca ttgtttccac tagcccatga
    12061 ggatgaaaaa ctggatgcca gcgataggtg atcattcctt gttgatccgt tcgccatgtt
    12121 tttatctgat tttcttctag tgtctccaat acttcgctgt gcgggtgacc ataacgatta
    12181 tttacgccgc aggatataat cccatgtttt gcttcaatat gggaaagaaa atctgtgtta
    12241 cttgacgtac ggctaccgtg atgacctaat ttgactacat cggctttcag attaggataa
    12301 atcaaaagca attgtttttc cattgcttga ttcaaatctc ctaaaaataa aaagcgccta
    12361 ttgttatatt ccatccatag accaatcgaa tcttcatttc ttccctctcc cttttcaaaa
    12421 ggagtcaata cataaagatc ataataaccg ctgatcctgt ccccatgttt gatttcaatg
    12481 atctcagtac catttttttg agcttcagat aaatgccttt gtaatggctc atttcgtcca
    12541 gcgccccaac cgatataaat ttttttgata gtaaaatgct gagataacgt gggtaattct
    12601 cccacatgat ccgtatcgtc gtgtgtcaag atgagtttat cgattacact tatcccctga
    12661 ccttttagat atggaacgat atttctttca gcaggaggac gtatcatacc ttgcgcccac
    12721 ttttctcttt caaagtgtaa ctgacctcca gtatcgatca aaatcgtttc ttttcgaaaa
    12781 ggactttgca aaaagatact gtctccttga ccgacatcga taaaagcgat cgttgaagaa
    12841 aagcgtaaaa atggcaaagt caaaaaaata aaagaaaaaa gaccaacata aaacaagtgt
    12901 ttcacaggtt gttctttcaa cctatccata caaatcagta atccgaaaat atacatccca
    12961 gatagcacaa ggggcaaacg tcctataatg agagacgacc ctgaagaaaa atcgattatt
    13021 cgctcaaata agattaatcc ctcttctatc agcaaaagta aagtttccgg cagccagcga
    13081 ttgaagagtg tgagaaataa cacaccagga agaaaaagaa acttgaatac cggtgcaatc
    13141 agtaatgtaa aaagactacc taaaataggc cactcataaa aatgccatac aatcaacggc
    13201 atcgtgatca tagtaaacag gacgtgagag gccgtttttt tcaaccaatc tccatcaaaa
    13261 gaaatcagga taaacaaaaa actcatgaaa aaactaagct gtccacccgc atgaaaaaga
    13321 aatcgaggat caaatagtaa aagaagccaa aagacaactg caaataagtc catggtggaa
    13381 taatgcttat tcagcaattt gactagcaat cgcaataaaa acagcaaact agcacgcaaa
    13441 acagaaatag aacttcctgc aatagaaaca taacagatag ttagtagact caacggaata
    13501 atactgacgt gtagtggcca tccgatacgt cgaaataaat aatacagcca ccctaaataa
    13561 aattggatgt gtagacccga tagactgaac agatgcagca aaccactctc cctaaaaatt
    13621 tcttctggtt ctctgaatcc tgcatcttta tagccccata ataaagaatt aatatataca
    13681 cttgtttttt gcggaaattc agattggaca aaggagataa aagatcctct ttttctctga
    13741 agccagtttc gccagtgatt ttgcatggtg atctgttcaa tcttttgaat ttggaaccgt
    13801 ccagaaattc tatggttcct gaagtaagct tcttggtcaa aattataaag attccgcttt
    13861 tttgctggag agatgaactc gccttcagca gtcaattcta ttccctttcc tcggaagtta
    13921 agccatgttt tcaattctgc ttctgtgttt acttgataag aaagctggag cttttgttta
    13981 ttctctgata accttccttc cattgtcaaa aaattaccat ttgcacgaat cgtatctgta
    14041 aatacagtaa tttgcgcaga tgttgttttt tcctctaaaa atgaatactc ttgtagccta
    14101 taagaaatgg ataccgttat gctacacaaa atacacaagt acgcgataaa acgtccttct
    14161 tttagcgaaa accataaaaa
//
LOCUS       DAPBBR010000063        13732 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.066, whole genome shotgun sequence.
ACCESSION   DAPBBR010000063 DAPBBR010000000
VERSION     DAPBBR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.066"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(63..1268)
                     /locus_tag="RD488_002223"
     CDS             complement(63..1268)
                     /locus_tag="RD488_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7658282.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="RD488_002224"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="RD488_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="RD488_002225"
     CDS             complement(1447..2832)
                     /locus_tag="RD488_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7658283.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="RD488_002226"
     CDS             complement(2861..3247)
                     /locus_tag="RD488_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7658284.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="RD488_002227"
     CDS             complement(3263..3577)
                     /locus_tag="RD488_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7658285.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="RD488_002228"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="RD488_002228"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDT7658286.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="RD488_002229"
     CDS             4837..6126
                     /locus_tag="RD488_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDT7658287.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(6165..6770)
                     /locus_tag="RD488_002230"
     CDS             complement(6165..6770)
                     /locus_tag="RD488_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDT7658288.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(6966..7430)
                     /locus_tag="RD488_002231"
     CDS             complement(6966..7430)
                     /locus_tag="RD488_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7658289.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(7452..7772)
                     /locus_tag="RD488_002232"
     CDS             complement(7452..7772)
                     /locus_tag="RD488_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7658290.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="RD488_002233"
     CDS             complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="RD488_002233"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HDT7658291.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            9194..9544
                     /locus_tag="RD488_002234"
     CDS             9194..9544
                     /locus_tag="RD488_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7658292.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            9729..10682
                     /locus_tag="RD488_002235"
     CDS             9729..10682
                     /locus_tag="RD488_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7658293.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            10695..12482
                     /locus_tag="RD488_002236"
     CDS             10695..12482
                     /locus_tag="RD488_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658294.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            12469..13671
                     /locus_tag="RD488_002237"
     CDS             12469..13671
                     /locus_tag="RD488_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658295.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         3938 a         2689 c         2519 g         4586 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa aaagaggttg tgacaaagac ttgtcacaac ctctttattt tggaaatact
     6181 tctccgacta cggcatcctc aggcaatact aagattcctt ttttttctgg agcatttggc
     6241 aaatgcaatt cacgagcaga acaaatcatt ccatagctgg ctacccctcg caaagttcct
     6301 ggccagatca tcattccatc tggcatcatg gctcctggtt ttgcaacgac aactttttgt
     6361 ccagcttcga tatttggtgc accgcaaaca atttgcaata ctgtcccatt gtccacttct
     6421 gtctcagtaa tcgataaatg gtcagagtca ggatgcggga cgcatgtttt tacatacccg
     6481 acaacgatct tcggttcatg atcagcttca agctgttctt cgaatcctgc ttctttaatc
     6541 aatcgattca atttcgctaa ttcttcatct gttaagctta cttggccgtt cccttcaatt
     6601 gttagatgat cggagatatg gaaaaagttc caagcaacaa cttgaccttg ttcatctttg
     6661 atccgagcaa cattccattt acgttcgaca gtgttttctg ttcctttatc gtcggctatg
     6721 ataaccatca aagtgtctcc gacgtgtgct ttgttataag caaaaatcat gttctttcct
     6781 ccattatcct ttgctgagat ttatcttaac aaaaaattgc attcactgca tgagattttt
     6841 ttcatgcttt atttccgaag aagcttcttc tggaacacca tttattcgta acaagggact
     6901 gtgacaagac ttttgtcaca gtccctttac tgtttgatta aaaaggttat acaagttcca
     6961 cttgcttaat tactcggctg ttcttcttcg tcagaaacga tcaagacatc acaaggtgaa
     7021 tgacgtatga cgtagctggc tacacttcct gtcataaagc gttcgactgc atttagtcca
     7081 gactgcccaa ccatgattag atcgattgca tatttttttg gcaatttgac tgccatggat
     7141 tcacgaacag agccgtatgc aataattcct tctatatttg tgtaatcaac agattttcca
     7201 tattctttac attcttcgat catttgcttg gctgtttcag tttgctgatc gactagattt
     7261 tgatcaatag gagcatagcc cataaaatta taaaattgct gatcgattac gtttgctaca
     7321 tatactttcc cattattacg gcgagccact tctaacgctt ttttgaaagc agcaagtgct
     7381 tgttcactac cgtcaatacc tactaaaatg ttcttatatt cttgattcat cttgacccct
     7441 cctaacagat gtcagccttt tattacactt tctaggaacg attcgatttc ctgttttgtt
     7501 ttacgatctt tattcactag acgacctaat tcttttccgt cttggatcac gacaaaactt
     7561 gggataccaa aaatgttcca ttcagcggct acatctatgt acttgtcacg gtctacttca
     7621 ataaattgcc aatcagaaaa gtcattttcg atttcaggca tttgcggttt gataaaacgg
     7681 cagtctccgc accagccggc agtaaagaaa aatacacttt ttccagtttc tacgtagcct
     7741 gctaattctt ctaaactatt tgggataatc attctttttc ctctactttc tgtttatgta
     7801 tttttcaatt aaattataca cctttctttc gaactaacaa acattgatcc tctttttata
     7861 aaaaaaatct gacaaaaggt tgcttttgcc agattttata gtttcactat cgcgttattt
     7921 cccgtatacg atcgtgttca ctgttgattt atctaaacct ttcaatgttt gaatcaacat
     7981 ttctcgtgca gcttcaaaat cgcgaatact gaacatcgtt tgatgcgtat ggatataacg
     8041 tcccactacg ccaatcactg tacttgggat tccttcattt tgtgtatgag cagcacctgc
     8101 atctgtaccg ccttttgaaa caaagtattg ataagggatg ttgtttgttt cagcgatatc
     8161 tagcaagtac tcacgcaaac gaggaagcat gatcaaacct ggatcttgga tacgcatcaa
     8221 tgtaccttct cctaaatgtc cgaatgtgcc atttttcgtc actgtgtcat ctgctgcaga
     8281 gcagtctact gcaaagaaca gatctggctt gaatttattg acagaagctt tagaaccacg
     8341 caagcctact tcttcttgga cattcgcgcc tgcaatcaat gtatgaccta atgtttcatt
     8401 ttgtaacgct tctaaagctt ctaataccat tgtacagcca tagcggttgt cccacgattt
     8461 gctgatgata ttcttcccgt tggctgtttt gatcgtttca gcgtaaggaa cgattgtgtc
     8521 tcctggaaga acaccgtaac tcattgcctc ttctcttgat tcaaacccag catcgaacaa
     8581 aatatctgtt acttctactg atttttgtcc gcttgttcct cgtaataaat gtgggggaac
     8641 ggaagaagaa atacatggat aattcttacc agtagaggtt ttaagtgtaa aacgttgagc
     8701 agaaacaacg taagggttcc atccgcctag aggtacgact ttaaaaagcc cgttttcttg
     8761 gatttgtgtc agcatgaatc cgacttcatc catatgtgct gcgaccatta cacgaggtgc
     8821 atccgcttct tcatggtggc gcagcccaaa aatgccgccc aaaccatcta actgtaactc
     8881 atctaccagc ggttccatat gactttccat ataggcgcga acgtcttgtt caaaaccgct
     8941 tgttccttgt aattctgtta actctttgat tcgttgaaat gttttttctt ccatatgcta
     9001 ttcgtctaaa tttcagacta aactcctctc agacttatat tgatctgcgg ataaaatatg
     9061 attttttctg cagaccgatc gtatttatta tagcttattt tttctggtag cggttattta
     9121 tttcaaagaa aatatgagag tgtggtaaaa taaacacaaa gagtagcaag tgagaagaag
     9181 gaggtatatc cacatgtatg aagaaagcga attaagctat tttaaaggcg ggttagccgt
     9241 tgggatcggt ctaggattat tgagtggggt agcttcaacg atttggtatc atcgcaaaaa
     9301 agtgttatca gcagaccaag tgcttgaaaa tatcaaaaca tcttttttaa aagaaggcgc
     9361 aatcgaaggt gcttggatct cttttgaaaa agaacctatt cggaaattcg ccgttcggtc
     9421 gagtgcttat cggggtgggc tttcccggat agaagatggc gaaactgttt attatgaatt
     9481 tttagcagat gctcatacag gaaccgtatt agacatttca agaaaaaagg gcgcaataga
     9541 ttaatacgtc aaaaaaatga aataacgaat acgcacccac tatctaaaag agaggtatcc
     9601 tatccttctt ttatagtggg tgatttttat aaaaataggg ctatttcctc ttggaatagc
     9661 tagtatttgt agttattata cggtattctt gaaataagat tagttttatt atataaggag
     9721 agtgacaaat ggaatcacgt gaaaaaattg ccgtgctcat tccttgttat aacgaagagg
     9781 cgacaatttc aactgttatt gaagatttta aaagggaatt accagaagca gatatttatg
     9841 tctatgataa taattcgacc gatcgaacat acgaattggc cgttcaaggc ggagcaatcg
     9901 taaagaaaga accacgtcaa ggaaaaggga atgtaatccg tcaaatgttt tttgatattg
     9961 atgccgatta ttatttgatg gtagatggtg atgatactta tcctgcagaa gctgcacatg
    10021 gtttgcttga gaaattacgt tctggcgaag cagatatggt cattggcgat cgtctatcaa
    10081 atggaaccta ttttgatgaa aataagcgtc ctttccatga ttttgggaat aatctggtta
    10141 aaaatacaat tacttactta tataaaacaa aaattcgcga tgtcatgacc ggctatcgag
    10201 gattcaatcg aatttttgtc aaaagcttcc ctattatgag ttctggtttt caaatcgaaa
    10261 cagaattgac gattcatgct ttagataaaa aattcaagtt cgttgagatt ccaatcgatt
    10321 atcgcgatcg tcctgaaggt agcgaatcaa aattgaatac attctctgac ggattcaaag
    10381 tgatcatgat gatcatcaaa atgtgcaaag attataaacc tttgcttttc tttgggatct
    10441 ggaccatctt cttcttttta tttggattgg tcatggggat tcctgtgatt cgtgaatata
    10501 tgctgacaag ctttattaca cgcatccctt ctgcgatttt aagtactgga ttgatgactt
    10561 tagcccttct ttcattagta acagggttga ttttggatac ggtcgtcaca aatgccaaga
    10621 aagaatatga attgaattta taccatgtct accacgaata tcaaaataaa gaaatgaagt
    10681 aggaggcctt ttttatgcat aagaaaaagg agaatctatt tcctactttt tttgcaactt
    10741 tatttgcgtc aggttttgct ttttttactt cttatggtct aggaactttg aatccaacag
    10801 taatcattgg tttagccatg gttttgctac ttgcttttaa gcaatatgga atagagttgt
    10861 tttcaataaa aaacaaagtt gcagctattg cccgattgtt tttttctgca gcttttgctc
    10921 ttacactttc tattggcaga cagatacaat ttcagtatgt ctcagcaaac tatacaaaga
    10981 caacgattgc tgatggaagt attttttact ttcttgttta tttctccatt tttgtgtatt
    11041 cttttttatt tttacaatcg atttatttat caatgccaaa actggaaaca ttttttactg
    11101 ctcaaaacac acaggctttc tcttcaagaa aatatttttt attctttact gtctttttag
    11161 ttctgtgttg gcttccttat ctgttggcat tgtatcctgg agtggttttg cctgattcgt
    11221 taagttcggt cgcccaatct atgggtgatg ttcctataag caatcatcat ccagtcttat
    11281 tcaccttact ggtcaagcta tttgttcatg atttaccaac tgatacgatc aatcacggtg
    11341 tatttttatt ttcgattttt caaacattga taacagcttc agcgataagt tattctcttt
    11401 gctggctgtt aaaaagaaac atccattttt ttccggtact cattagttta tgctattttg
    11461 catttgcacc ggtttttcca atctacgcct tgaacatgca aaaagatact ttgttctcta
    11521 tcgcttgctt tttattttcc ttagcggttt ttgactttat ttttcaacga gaaaagccaa
    11581 cgattctcaa tcagatttac gtaatcatcc ttgctttact gaccacctat ctaagaaata
    11641 atgggattta tgtagtaacc ggcacaggtt tgatttgcgg cttgattatt ttgaaacaaa
    11701 aaaggtatca agcattcttt caagtggtgc tgggttatac agtgattgct ggactactca
    11761 tccacccgtt gatggctcgt tatgctattc ctacagaaac tgctgaacaa ttaggtgttc
    11821 ctttgcagca aatttctaga actattgtta tggatggtga cttgtctaag aaagataaag
    11881 cattcatgaa tcagctactc ccgataaaag attatgaagc gtattctcct agtcttgcag
    11941 actcaatcaa gtggcataaa aattttaaca atgagttttt gaatacacat aaaaaagaat
    12001 ttctatcact atgggcaaga aatttaccaa gtaatataaa aatctataca gatgcttata
    12061 ttttagaaac gttcgggttc tgggtacctg gtacaaaaaa tagttacggc tttttagata
    12121 ctcgtgtaaa cacgaataat tatggtatga agcaagtaga tttgattgaa catcttactg
    12181 gattgtcagg aatgaaaaaa atcatcgatg ctcgtgattt ctttggttcc ggcacattac
    12241 tgtggttagc tatcggcagt gcacttttag caatctttaa gaaaaaatat cggtatttac
    12301 tcctttttct tcccggtatg cttgtttttg ctactattat gattgctact cctgtggctt
    12361 ttagtttacg gtatgtgttt gttttagcat taggtctacc tgtttatatc ctctctcctt
    12421 ttttactaga taaaagagaa aaaatgaaaa cagatatagg agatactcat gaaactattt
    12481 aaaaagatat tttttgcttt tgttctcttg atcgctagct attgcgtact actgacaatt
    12541 acttttttca ttccgcagca ctctattgaa tcgaatgcag aaaaatctct acagatggtt
    12601 gaaaaagaag gaatgtatcc ttctatcaat caaggaaata tgctaggcac tcggttagat
    12661 aattttactg atcatttgat gatacgaaaa acaaaagcag atcctgaatt gaactccttg
    12721 gagaacgcga tgtctatggc ggattatccc cgttattggc atggttatca gcttttttta
    12781 cgacctttac tgctagggat gagtttgggg agtattcgaa tgatttacgc agccattctt
    12841 tttctgctga ttggattgac gagctacttt ttaaccaagt gtagcgacat ctatttaacg
    12901 acagccttgt tgatttcgct tgctatagga aatgctgcaa cctttttctt cagtatgcaa
    12961 ttttcaaata tttggatttt gactttattg tctgtattac tatttttaac aaaaccacaa
    13021 ctctccaaca ccaaccaaca attattcttg tatttctttg tcattggttc tttagctaac
    13081 ttttttgact tgttgacaac accggtcatc tcttggggga tacctgtgat cattatttat
    13141 tatgtaacaa ataagtattt aatggataaa cgcagttcat tgagcaaaca agtaggcagt
    13201 tttgttttta ccggtatctt ttggggatta ggctatggtt tgacatgggt ggctaaatgg
    13261 atcctatcat cgatcatatt gaacaaaaac attgtaaaag atgcaatcaa ccaaatcctc
    13321 tttcgaacgg aaggaaacga caaatacccg ttgcatcgat tagagatgct gaaaagcaat
    13381 attagattga tgtatccaaa agtagcaata ttattgctat tgattacttg tcttgttttt
    13441 ctctattttg cttatcgtaa acgaaatagc tggcgtccgt tccaacttct agttttgttt
    13501 gttttagctg ctgtaacgcc gtatatttgg tacaatattt tagctaatca ctcacagatt
    13561 cattattggt ttacgtatcg tacgcaaatc atcacaagtt ttgctatact tagtgctttc
    13621 gcctttttga tccctcctga gaaatcaaaa gacgaactaa attactttta agaataccga
    13681 tgtactaatt catttttaaa cataaaaact ccagctgtca gagatagccg ga
//
LOCUS       DAPBBR010000064        13700 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPBBR010000064 DAPBBR010000000
VERSION     DAPBBR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.067"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            577..1473
                     /locus_tag="RD488_002238"
     CDS             577..1473
                     /locus_tag="RD488_002238"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658296.1"
                     /translation="MTKYIMVIFSLVVLTACSKGEDSTVVESTSTDSTTVETSVTSTT
                     KSSTEEISTSSTETTQDFPYAVNLNDFIQEVKPNGNEANKKTISHLTFVTNQKNVPTT
                     ITLNTKDLNDFGNGIYISSDTEEVFYPVSINEIPTQNIILVGDNGEEREVKVNTEVKI
                     EVPNDDQSDSFQIVGDSYYLFYNQQETISLATRNFDENPGSKDLDNSNMIEYVQQVDS
                     QNTEDSEPTENTKSDEYYHSIKEAWNKQKDYVDGIEDPKIKQATQTPFSAANAEATRL
                     EQENPEDAEVIKASLKRVLDGE"
     gene            1485..2405
                     /locus_tag="RD488_002239"
     CDS             1485..2405
                     /locus_tag="RD488_002239"
                     /inference="COORDINATES: protein motif:HMM:NF019556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HDT7658297.1"
                     /translation="MSGYDGHPEIELALGRLYELTQKESYLTLAKFYIDERVQDDFFD
                     RQIEADGFERDVIDGMRNFPLSYYQAAEPIREQETAEGHAVRVVYLCTGMAKVGRYTN
                     DESLLKACKRLWNNIVEQKMYITGGVGSTNIGESFTGNYDLPNDTMHGETCASVGMAF
                     FAKEMLELESKGEYADVLEKQLFNGIISGMSLDGAHFFYVNPLQADPEVSEHNPSRNH
                     VLTDRAEWFGCACCPSNVARLVASVDHYIYTVKDTMILSHQFISNDATFESGVTIIQT
                     SNYPWEGQIYYEINNPNDVETTLGIRIPAW"
     gene            2448..2876
                     /locus_tag="RD488_002240"
     CDS             2448..2876
                     /locus_tag="RD488_002240"
                     /inference="COORDINATES: protein motif:HMM:NF019556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658298.1"
                     /translation="MKVENGFIYFKLLAGSFEILLTLDMVVKKYQANQQIAHDFGKVA
                     IQRGPIVYCVESMDQTEDVWKYQLIQAGEIAYAFDDKLLNGVGVIRAEAKVANGRSAS
                     VYQEYQPLTRRAAELKLIPYYAWANRGKNQMLVWIDQNDC"
     gene            complement(2972..3841)
                     /locus_tag="RD488_002241"
     CDS             complement(2972..3841)
                     /locus_tag="RD488_002241"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014376.1,HMM:NF024242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7658299.1"
                     /translation="MEIENLNLYRDSAWNDLKIRFCGHSECLPLHSYGPGSRPYYLLH
                     FVLSGKGKLLVNKTEYQIEAGQLFLVEPDQMVFYQADEDTPWTYSWVGFNGGLASHFI
                     NRLGLGYPTLTRDIEPDTFIEIKKLLENIIKSNINNTVNDLYINGQFLILLSKIGTDE
                     FGKEMIIDEEKYSAEKYVQEAIMIVEDFYGTELTVNDIANRLNINRSYLSSIFVKHVG
                     TPLKKYLVEFRISQSEEFLFTTNWSVDYISKVCGFNNPSYFSKIFKKFHGLSPTEYRE
                     QRHLRRSQTVFID"
     gene            4222..5484
                     /locus_tag="RD488_002242"
     CDS             4222..5484
                     /locus_tag="RD488_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008376091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 27 protein"
                     /protein_id="HDT7658300.1"
                     /translation="MRNLRNFAKTPPKGWNSWDVYGASVTEEEVRRNADVMATKLKDH
                     GWDYVVVDIQWYEPTADSAAYHVFAPLNIDEYSRVMPAENRFPSAKDGNGFKDLGDYI
                     HSLGLKFGIHILRGIPREAVHKQMKIKGTTKTADQIAFNSICPWNSDMYGVNVNIPEG
                     QMYYDSILEMYAEWGVDFIKVDDIAYSTIYREAHLAEIAAIRKAIDKTGREIVLSLSP
                     GPARLQDGSFLQENANMWRLTDDFWDDWELLYDMFDRCNYWSPFIRPGNWPDCDMLPL
                     GHIGIRSGERGFPDRNTNFTKPEQKTMITLWSIFQSPLMYGGELADLDDWTLSLLTNE
                     EINSMHSSLTKQKQESRNENWIVWSGENEKDKYIAIFNVSNNEQDIPEEILNEYIQTE
                     NAKELWSGDSKDAFNKTLESHDCAIFKL"
     gene            5654..7030
                     /locus_tag="RD488_002243"
     CDS             5654..7030
                     /locus_tag="RD488_002243"
                     /inference="COORDINATES: protein motif:HMM:TIGR00792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7658301.1"
                     /translation="MDTIGKSLGLKEKMAYGCGDAASNIIWASMGAFMMFYYTDVVNI
                     SAATIGTIFLISRVINAVVALATGWLIDNTKSKYGKARPWLLWFAVPFAIVTFAIFSV
                     PDIAKLYQVIYVFITYNAMMTVYSLINIPYGSMATMMTKDQYQRTLLNIFRQLFAQIA
                     SLLVTAFTLPLVKVFSSSVGEKNAWSVVYGIFGIAAGVLFFLCFIGTKERIHDNEVVK
                     EEKINIVKGMKSVLKNNYWVMLMVISISINIFFQAISTVNTYYCKAVLHDSNMIGILN
                     TAYIVPAIVAFFFVHLIVKKFGKGYTTMFGWIIICASYAVLLPFTENHMALIITSAMR
                     GVGYCFLLAVSSAMVSDAVEYGEWKTHVRVEGLTFSMQGFVTTIAAGLVTAFIGGVLD
                     FSKYDGTLTFAQAQPVTAVTAIKLLFIAMPFIVGALNVLLLKFYKLDKMYPKIIEDLN
                     MRNSVTTK"
     gene            7158..8567
                     /locus_tag="RD488_002244"
     CDS             7158..8567
                     /locus_tag="RD488_002244"
                     /inference="COORDINATES: protein motif:HMM:TIGR00792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7658302.1"
                     /translation="MKSIISDEKECSKEEKLSSGFKTSITEKIAYGMGDVACNVVYAL
                     TSGLLVYFYTNVIGVPAGVIGTILLLSRIFDGISDLLIAQLMDKINSKHGKARAWVLW
                     MSIPYALTAVALFLVPANATLMVQTVYIFITYNLCTTVVYTGLNLPYSAMAPLMTNDD
                     DDLAKLNLFRMSMSPISNLIVTAVSLPFINMLGGDQRAWIIVTAVYGVVAFGMLIWTF
                     LGTKERFHTSAAAEAEELPFSQRLKATGKNKYFIIMFLTVICLSIYQNVNGTVSTYYA
                     QYILGNAELMGLMQTFEKVPWILGIMFMAPLIRRFGKRNLVLFGAILCVGAQVLIMFN
                     PSNLNLILFSAVLRGLGEAPINGLTFTMIADVINYGHWKTGIRVHALIFSTFTVGQKF
                     GGGITGWAIGQLLEVSGFSGSVTEIPSAVSMVQNLYIYGTILAWALVAVCMLKYHLDK
                     EYDEIMVDLKNREGDKLTV"
     gene            8684..9763
                     /locus_tag="RD488_002245"
     CDS             8684..9763
                     /locus_tag="RD488_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7658303.1"
                     /translation="MSKSKYQIIAEEIKGKIESNEYGFNQTIPPEMQLQKDYAVSRHT
                     VRQAIAVLVNEGYLRKEKGSGTYVDNRFKNDSKVKATPKTIGVITTYLSDYIFPSIIR
                     GIEGTLRSKGYSLLLASTNNDYQQEKECLEKMINYGVQGLIVEPTKSNQYNPNLALYV
                     SLKEQGIPMVMINAVYEELEAAYICVNDVRSGFLATELMIKKGNKNLLLVSKIDDLQG
                     KYRMKGFIQACEKYGVKIQSQDIITYTTDTRKQVSSIVLKRLKEEKKINGIVCYNDQI
                     ASVIVDNLNSQEISVPDDISIIGNDDSSLSKVGSIKMTTLKHPKVEMGKDAAEWIIKT
                     IEKNSEQKSILYEPILIERDSVLNR"
     gene            9915..11504
                     /locus_tag="RD488_002246"
     CDS             9915..11504
                     /locus_tag="RD488_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDT7658304.1"
                     /translation="MTKADIMLDIIDGRTSLGIEFGSTRIKAVLVASDLSPIAAGSYE
                     WENQLENGIWTYSLDDVWKGLRISYRKMAAEVFEEYGETLSTIGSLGFSAMMHGYMAF
                     DAENDLLVPFRTWRNAITEEAEEKLTKAFRFNIPQRWSIAHFYQAILNKEKHVGNVTF
                     FTTLAGYIHWQLSGEKVLGVGDASGMFPIDVAIKDYDQQKIAIFNNLVKKEDMDINIK
                     SFLPRVLLAGEAAGNLTQEGAYLLDPTGTLKAGIPLCPPEGDAGTGMVATNSVAKRTG
                     NVSAGTSAFAMIVLEEDLKEVHPEIDLVTTPSGEHVAMVHTNNCSSEINSWIKIFKEF
                     TETLGFEISTESLYDKLFSKALDGDPDCGGLLSYGYHSGENITGVNEGRPLFVRTPDS
                     KFDLANFMRVHLSSAFGAMRIGMEILKKENIKIDKLVGHGGIFKTPEVGQRILAAAME
                     APVTVMETAGEGGAWGIALLASYLTDKNNLTLEEYLSTKVFAKSEGITIEPTNEDIEG
                     YAKFIDRYEKGLSIEKASVVV"
     gene            11524..12222
                     /locus_tag="RD488_002247"
     CDS             11524..12222
                     /locus_tag="RD488_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7658305.1"
                     /translation="MLEQLKEEVFQANLELPKQGLIKYTWGNVSAFDSESGYFVIKPS
                     GVSYEAMKASDMVVVDLDANVIEGKMNPSSDTPTHAILYEKFPEIGGICHTHSTWATI
                     WAQSGLDLPAMGTTHADTFYGTVPCARFLTQEEIENGYEKETGKVIVDTFKKREIKEL
                     EVPGVLLHGHGPFTWGESAKAAVMNAVVLDEVAKMNLFTRQLNSFAEELPQRVLDKHF
                     LRKHGKNAYYGQAK"
     gene            12241..13665
                     /gene="araA"
                     /locus_tag="RD488_002248"
     CDS             12241..13665
                     /gene="araA"
                     /locus_tag="RD488_002248"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDT7658306.1"
                     /translation="MLEIRKKEFWFVVGSQHLYGEEALKTVKMNAQAIVKGLNDSGKL
                     SYPIVLQDLAVTSDKITEIMKEANYRDEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQFNESIPWETIDMDFMNLNQAAHGDREYGFINARLRKQNKIVVGYWQTSGVQDQI
                     SAWMDVAAAYNESFNIKVARFGDNMRNVAVTEGDKVEAQIQFGWVVDYYGIGDLVQYV
                     DAVTDGEVEKVFAEYKDLYDFDYGDYEKEVWEAHVKVQARQEIGIRRFLEAGNYNAFT
                     SNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAALDRLMKVMAHNENTGFMEDYT
                     YELASGKESILQSHMMEVDPTLAVNKPKIVVSPLSMGDREDPARLVFDGKAGAGVVVS
                     MADFGTHYKLLINEVDLFEPTEAAPKLPVARVLWEVKPNFHEGVGAWIEAGGGHHTVV
                     SLNLTTDQIQTWAKMVDLEFVTIK"
BASE COUNT         4557 a         2026 c         2843 g         4274 t
ORIGIN      
        1 ataaaactat ctttttattt taatcatgac gaaaaaggtc aaaggcttag atatattaat
       61 ttggagcaaa aataagatgg ataaactttt cattaatata ctttagagtg aacgaagttt
      121 gaaatataag taaagaagaa aattgagaaa aagattgttt ggctaacggg aaaagtcgtc
      181 ttatcctcag gatcaatctt ttttctccct ccattcacca gtcgaattac cttcgtttac
      241 gaagttgaac atagacaaac gattgaaaga gtggttcttc aaagctagct cccacttttc
      301 agcctaagaa agaattagaa aatttttttg aggaacatcg agatgaatgt tttataaaag
      361 atacttatat gttagcaatt cttttcgttt atctttttct agattctgtg taatcgtttt
      421 agttgtaatt taatacactc tttgttacca tttctatata gtatagttgt aaaaattttg
      481 atgtttaaat atggagtagt gttatttatt ttttagttcg atgcctaaat tttttgaagg
      541 attttgttat atttttatat aaaggatgtg gcggttatga caaaatatat aatggtaatt
      601 tttagtcttg ttgtattaac agcttgttca aagggagaag attcaactgt agtggaatca
      661 acttcaacag attctactac agttgaaaca tcggttacct ctactacaaa gtcaagcact
      721 gaagagatta gcactagtag tacagagaca acacaggatt ttccttatgc cgtaaacttg
      781 aatgatttta ttcaagaagt gaaaccaaat ggaaatgaag cgaataaaaa aactatttcc
      841 catcttactt ttgttacgaa tcaaaaaaat gttcctacta cgattacttt aaatacaaag
      901 gatttaaatg attttggaaa tggaatctat atttcttccg atacagagga ggtattctat
      961 ccagtttcaa ttaatgaaat acctacccaa aatatcattc ttgtcggaga taatggggaa
     1021 gaacgagaag taaaagttaa cactgaagta aaaatcgaag tgccaaacga tgatcagtca
     1081 gattcgttcc aaatagtagg ggatagctat tatctctttt ataatcaaca agaaactatt
     1141 tctttagcaa ctcgaaattt tgatgaaaac ccaggatcga aagatttaga caatagtaat
     1201 atgatagagt atgttcaaca agtggattcg caaaacacag aggactctga accaacagag
     1261 aacacgaaaa gtgatgaata ctatcattct attaaagagg catggaataa acaaaaagat
     1321 tatgtagatg ggattgaaga tcctaaaata aaacaagcta cacagacgcc tttttctgca
     1381 gcaaatgctg aagcaacgag gttagaacaa gaaaatccgg aggatgctga agtaataaaa
     1441 gcaagtctga aaagggttct tgatggggaa taatttaggg gaaaatttct ggatatgacg
     1501 gccatcctga aatcgagctg gcactaggtc gcttatatga attgactcag aaagaaagtt
     1561 atttgacatt agcaaaattc tatattgatg aacgagtaca agacgatttc tttgatcgcc
     1621 aaatcgaagc ggacggattc gaacgtgatg tgatagatgg tatgcgcaat tttccattat
     1681 cttactatca agcggcggaa ccaattcgag aacaagaaac cgcagaaggt catgcagtgc
     1741 gggtcgttta tctttgtaca ggaatggcga aagtcgggag atatacaaat gatgaaagtt
     1801 tattaaaagc atgcaaacgt ttatggaaca atatcgttga acaaaaaatg tacattacgg
     1861 gtggtgttgg ttcaacgaat atcggagaat ctttcacagg aaattatgat cttccgaatg
     1921 atacgatgca tggagaaact tgtgcatccg tcgggatggc cttctttgct aaggagatgc
     1981 tagagctaga aagcaaaggt gaatacgccg atgtcttaga gaaacaatta ttcaacggaa
     2041 tcattagtgg catgtcatta gacggcgcgc actttttcta tgtgaacccg ttgcaggcag
     2101 atccagaagt ttcagagcac aaccccagtc gtaaccatgt gttgacagac cgggcagaat
     2161 ggtttggctg tgcttgctgt ccaagtaatg tggctcgact tgtagcttca gttgatcact
     2221 atatttatac tgtcaaggat acgatgattt tatcccatca gttcatttca aatgatgcga
     2281 ctttcgaaag tggcgtgact attattcaaa cgagtaatta tccgtgggaa ggtcagattt
     2341 attatgagat caacaatcct aatgacgtgg aaacaacctt agggattcgt atcccggcat
     2401 ggtaacaaaa caattttgtg ttgaatatca atgggcaaga taagacaatg aaagtagaaa
     2461 acggctttat ttactttaaa cttctagcag gttcattcga gattttactg acattggata
     2521 tggtagtgaa aaaataccaa gccaaccagc aaatagctca tgattttgga aaagttgcaa
     2581 tccaacgagg tccgattgtt tattgtgtag aatcaatgga ccaaaccgag gatgtgtgga
     2641 agtatcaatt gatccaagca ggagagattg cctatgcttt tgatgacaaa ttgctgaatg
     2701 gtgttggtgt gatccgagca gaggcaaaag tcgcgaatgg acgatctgct agtgtatatc
     2761 aagaatatca accattaact cggcgggcag cggagttgaa gctgattcca tattatgctt
     2821 gggcaaatcg cgggaagaat cagatgttgg tttggatcga ccagaatgat tgctgatagc
     2881 aaaagatagg attaataata taatagactc ggtcggcata cggatttttg agatatctgt
     2941 gtactgaccg agttttagta atacagactt attaatctat gaaaacagtt tggcttcttc
     3001 taagatgtct ttgttcacgg tattctgttg gcgataatcc gtgaaacttt ttaaagattt
     3061 ttgaaaaata agaaggatta ttaaaaccac atactttact aatgtaatca accgaccagt
     3121 tagtagtaaa aagaaactct tcactttgtg aaattctgaa ttcaactaaa tattttttta
     3181 aaggtgttcc aacatgtttt acaaaaatgc tagatagata tgaacgatta atattcaaac
     3241 gatttgcaat atcattgaca gttaattctg taccataaaa atcttcaaca atcataattg
     3301 cctcttgaac atatttttct gcggaatact tttcttcatc aattatcatt tcttttccaa
     3361 attcatcggt accaatcttt gacaacaata ttaaaaattg accatttata tacagatcat
     3421 tgacagtatt attgatgtta ctctttatta tgttttctaa taacttcttt atttcaataa
     3481 atgtatctgg ttcaatatct cttgttaaag ttgggtagcc taatccgaga cgattaataa
     3541 aatggctagc caaacctcca ttaaatccca cccaagaata tgtccatggg gtatcttcat
     3601 cagcttgata aaaaaccatt tgatcaggtt caactaggaa gagttgccca gcttcaattt
     3661 gatattcggt tttgtttaca agtagctttc cttttccaga caatacaaaa tgtagtaaat
     3721 agtatggtct cgatccaggt ccataagaat gtagtggtaa acattcagag tgaccacaaa
     3781 atctaatctt caaatcattc catgctgaat cccgataaag atttaagttc tcaatctcca
     3841 atttaattcc ctccaataca aaaccaacaa aagttttata ctaactaaca tttttatcta
     3901 acagtttgta tatagtctat tatattataa atccagaggc aaggataaat gaatacgaat
     3961 acattagtaa tgctaacgta tggagtgtaa gactagaagt tatatttaat tttcaatttt
     4021 tgtgttattt tatattgatg attatagaac tactattcta acaaaagttt agcttcttaa
     4081 ttactttttg ggcaggttat atttgagaat ctccatttct aaatattgta attgcttatt
     4141 ttaaaaagac tggaaattct gataattatt aatatcaaat gatcgagaga tcatcgatat
     4201 atacacttta tttttgaaag gatgagaaat ttgagaaatt ttgcaaaaac tccacctaag
     4261 ggttggaaca gctgggatgt ttatggagca tctgtaactg aagaggaagt tcggcgcaat
     4321 gcggatgtga tggcgactaa attaaaagat cacggatggg attacgttgt tgttgatatt
     4381 caatggtatg agccaacagc tgattcagct gcctaccatg tgtttgctcc attaaatatt
     4441 gatgaataca gtcgagtaat gcctgcggaa aatagatttc ctagtgccaa agatggaaac
     4501 ggattcaaag atctaggtga ttacattcat agcttaggtt tgaaatttgg tattcatatt
     4561 ttacgtggaa ttcctcgtga ggctgtccat aagcaaatga aaattaaagg aactaccaaa
     4621 acagctgatc aaattgcctt taacagtatc tgtccgtgga actctgatat gtatggagtg
     4681 aatgtaaata ttcccgaagg acaaatgtat tatgactcaa ttcttgagat gtatgctgaa
     4741 tggggtgttg atttcattaa agttgatgat attgcttatt caacaattta tagagaagca
     4801 catcttgcag aaattgctgc tattagaaaa gcaatcgata aaacaggaag agaaattgta
     4861 ctatctttat cacctggacc agctcgtttg caagatggaa gcttcttaca agaaaatgcg
     4921 aatatgtggc gtttaacgga tgatttctgg gatgattggg aacttctata tgacatgttt
     4981 gatcgttgca attattggtc tccatttatc aggccaggaa attggcctga ttgcgacatg
     5041 cttccactgg gtcacatcgg gatacgttct ggtgagcgtg gttttcctga tagaaatacc
     5101 aactttacaa aaccagagca aaaaacaatg atcacacttt ggtccatttt ccaatcacca
     5161 ttaatgtacg gtggggagtt agctgactta gacgattgga cattaagtct ccttacaaat
     5221 gaagaaatta attcaatgca ttcttcactt accaagcaaa aacaagaatc tagaaatgaa
     5281 aactggattg tatggtcagg tgaaaacgaa aaagataagt acattgctat ctttaatgtt
     5341 tcgaataacg agcaagatat tccagaagaa attctgaacg aatatattca gacagaaaat
     5401 gctaaagagc tatggtctgg tgattcaaag gatgctttta ataaaactct tgaaagccat
     5461 gattgcgcta ttttcaaatt ataaaaataa tttgaacaaa aaaataaaat aaacataggc
     5521 ggaaagctga tttcaccctt aactctatca gctttccgca ctaaagatga tggaatcgaa
     5581 aataaaaatg aacttattca ttttatagtt atagatcggg tttatcacta gaataaggaa
     5641 ggttttgaaa aaaatggata ctattggaaa aagcctaggg ctaaaagaaa aaatggctta
     5701 tggttgtgga gatgcagcga gtaatatcat atgggcatct atgggcgctt tcatgatgtt
     5761 ttattacact gatgttgtaa atatcagtgc agctacaatt gggacaattt ttttgatttc
     5821 acgggtcata aatgcagtag ttgctttggc gacaggttgg ttgattgata atacaaaatc
     5881 gaaatatggg aaagccagac cttggttatt atggtttgca gtaccatttg cgattgtaac
     5941 gtttgctatc ttttcagtgc cagatattgc aaaactatat caagtaatat atgtatttat
     6001 cacctataat gcaatgatga cggtctattc attaataaat attccatatg gatctatggc
     6061 aacaatgatg acaaaagatc agtatcagag aacattgcta aatatttttc gtcaattatt
     6121 tgcccaaatt gccagtttat tggtaacagc atttacttta ccgttagtga aagtttttag
     6181 ttcttcagta ggtgagaaga atgcttggag tgttgtatat gggatttttg gtattgcagc
     6241 aggagtacta ttcttcttgt gttttattgg aaccaaagaa cgcattcacg ataacgaagt
     6301 agttaaggaa gaaaaaatca atattgttaa gggaatgaaa tcagttctaa aaaacaatta
     6361 ttgggttatg ctaatggtaa tctcgattag tattaatata tttttccaag caattagtac
     6421 tgtgaacacg tattattgta aagctgtatt gcacgatagt aatatgattg ggattttaaa
     6481 tactgcttat atcgtaccag cgattgtggc attctttttt gtacatttga ttgtgaaaaa
     6541 attcggtaaa ggctatacta caatgtttgg ctggattatt atttgtgcta gctatgcagt
     6601 attattaccc tttactgaaa atcatatggc tttgattatt acatctgcta tgcgtggagt
     6661 aggttattgc tttttattag ctgtttcatc agcaatggtt agtgatgctg ttgagtatgg
     6721 ggaatggaaa acacatgtac gtgtagaggg actaactttt agtatgcaag gatttgtcac
     6781 aacgattgct gctggtttag ttacagcttt tattggtgga gttcttgact ttagtaaata
     6841 tgacggaact ttaacttttg cacaagctca gccagtaacc gctgtaacag ccataaaact
     6901 attatttatt gcaatgccat ttattgtagg tgctttaaat gtattgcttc taaaattcta
     6961 caagcttgat aaaatgtatc ctaagattat tgaggatttg aatatgagaa atagcgtaac
     7021 aactaaataa tagcagttta cgatagcgac cagattacta ttgaattttg caggtagatt
     7081 aagaaatgag tacctatctg caaaattcga tacatttttg tatagtaaag aaagcgtttt
     7141 ataaaggagg attcccagtg aaatctataa tttcagatga aaaagaatgt tcaaaggaag
     7201 aaaagctctc aagtgggttt aaaacttcca ttacagaaaa gattgcgtat ggtatggggg
     7261 atgtcgcttg taatgtagta tacgcattaa cgtctggttt gctggtctat ttttatacaa
     7321 atgtaatagg ggttccggca ggagtgatcg gtacaatatt attactttca cgaatttttg
     7381 acggaatctc tgatttactg attgctcaat tgatggacaa aattaactcg aagcatggta
     7441 aagctcgagc atgggttcta tggatgtcaa ttccatatgc gctgactgct gttgcacttt
     7501 tccttgttcc agcaaatgca acgttaatgg tacagacagt ctatattttt attacgtata
     7561 atctttgtac tactgtagta tacactggat tgaatttgcc ttattcagct atggcaccat
     7621 tgatgactaa cgatgatgat gatttagcta aattgaattt atttagaatg tccatgtcgc
     7681 caatcagcaa tctgattgtt acggccgtat ccttaccttt tattaatatg ttgggtggcg
     7741 atcaaagagc ctggatcatt gttactgctg tatatggggt tgttgctttt ggaatgttaa
     7801 tatggacatt tttaggtaca aaagaaagat ttcacacatc tgctgctgct gaggctgagg
     7861 agttaccatt ctctcagcga ctgaaagcta ctggaaaaaa taagtatttt ataattatgt
     7921 tcttgaccgt gatatgttta tcaatttatc aaaacgttaa tgggacagtt tctacttatt
     7981 atgctcaata cattctaggg aacgctgaat tgatgggatt aatgcaaaca tttgagaaag
     8041 ttccttggat acttggaatt atgttcatgg ctccactaat acgacgcttt ggtaaaagaa
     8101 atttagtttt gtttggagcg attttatgcg ttggagccca agtgttaatc atgttcaatc
     8161 cgagcaattt aaacttgata ctcttttctg ctgtactaag aggattggga gaagcaccaa
     8221 ttaatggttt aacatttacc atgattgctg acgtaataaa ctatggtcat tggaaaacag
     8281 gaatccgagt ccacgccctg attttttcaa cttttacagt tggtcaaaag tttggtggtg
     8341 gaattactgg atgggcaatt ggacaactat tagaagtctc tggtttttcc ggttctgtga
     8401 ctgaaatacc ttctgccgta tctatggttc aaaaccttta tatttatgga acgatccttg
     8461 cttgggcttt ggtagcagtc tgtatgttga aatatcattt agataaagaa tatgatgaaa
     8521 ttatggtcga tttaaagaat agagaaggag ataaactaac tgtttaacaa tcacttagga
     8581 taaagagttt ccactttaaa tagcgggaac tcttttattt atgtatggta taataaaaga
     8641 gtcagtcgaa tttgttcgta catatttatt gtgaggtgga gaaatgtcta aatcaaaata
     8701 tcaaattatt gcagaagaaa taaaggggaa aatcgaatca aacgagtatg ggtttaatca
     8761 gactattcct ccagaaatgc aactgcagaa agattatgca gttagtcgtc ataccgtgcg
     8821 gcaagcaatt gcagtcttag taaatgaagg ttatctaaga aaagaaaaag ggtcgggcac
     8881 ttatgttgat aatcggttca aaaatgattc gaaagtaaaa gcgaccccta agacaattgg
     8941 agttatcact acttatttgt cagactatat tttcccatca atcatcaggg ggattgaggg
     9001 aaccttgaga agtaaaggtt actcactctt acttgctagt acaaataatg actatcagca
     9061 ggaaaaagag tgtttagaaa aaatgattaa ttatggtgtt caggggttga ttgttgaacc
     9121 tacaaaaagt aaccaataca atccaaatct ggctttgtac gtgagtttaa aggaacaagg
     9181 aatacctatg gttatgatta atgcagtata tgaagaatta gaggcagctt acatatgtgt
     9241 caacgatgta cgttcaggct ttttggctac tgaattaatg ataaaaaaag gaaataagaa
     9301 tctcttatta gtttctaaaa ttgacgactt gcaaggtaaa tatcgaatga aaggttttat
     9361 tcaagcatgt gaaaagtatg gggtgaaaat ccaatcacag gatataatta catatactac
     9421 tgatacaaga aaacaggttt cttcaattgt tttgaaacgt ctaaaagagg aaaaaaaaat
     9481 caatggtatt gtctgttaca atgatcaaat cgctagcgtc attgtagaca atttgaattc
     9541 acaagagata agtgttcctg atgatatatc cattattgga aacgatgact cttccttaag
     9601 caaagtcggt agtataaaaa tgactacatt gaaacacccc aaagttgaga tgggaaaaga
     9661 tgctgctgaa tggataataa aaacaattga gaaaaattct gaacaaaaaa gtattcttta
     9721 tgaaccaatc ttaatagaga gagattcggt tcttaatcga tagaataatt tgatgaatag
     9781 acctccaggg aaggtctatt tttttatatg tgtacgaaca aatttcgtcg aaattagatt
     9841 gacgtgtacg tacataaaat gtataattta ggtgttgatt aggataaaag gaggagatta
     9901 ttatcaattc agtaatgact aaagctgata ttatgctaga tattattgat ggccgtacat
     9961 ctttgggaat tgaatttggc tcaacacgca tcaaagcagt tctcgttgct tctgacctat
    10021 cgccaattgc tgctggaagc tatgaatggg aaaatcagtt ggaaaatggt atttggacat
    10081 actcacttga tgatgtttgg aagggcttac ggataagtta tcgtaaaatg gctgctgaag
    10141 tttttgagga gtacggagaa acattgtcta caataggctc tctgggattt agtgcaatga
    10201 tgcatgggta tatggctttt gatgctgaaa acgacttatt agtccccttt agaacttggc
    10261 gcaatgccat tactgaagag gctgaagaaa agttaacaaa agcatttcga tttaatattc
    10321 cacagagatg gagtattgca cacttttatc aagctatttt gaacaaagag aagcatgtcg
    10381 gaaatgtaac cttctttact acattagccg gatatatcca ttggcaatta tctggtgaaa
    10441 aagttcttgg tgtgggagac gcatctggaa tgttcccaat tgacgttgca attaaagatt
    10501 atgaccagca aaaaattgct attttcaata acttggttaa aaaagaggat atggatataa
    10561 atatcaaatc atttttacct agagttttat tggctggaga agctgctgga aatttaacac
    10621 aagagggggc gtatcttctt gatccgacag gtaccttgaa agcgggtatt ccattgtgtc
    10681 caccagaagg agatgctgga acgggaatgg tagcaacaaa cagcgttgct aagcggacgg
    10741 gaaatgtgtc tgcaggaact tctgcctttg caatgattgt tttagaagag gatttgaaag
    10801 aagttcatcc agaaattgat ttagtaacaa cgccttcagg tgaacatgtt gcaatggttc
    10861 atacaaataa ctgttcttct gaaattaatt cttggataaa aatatttaaa gaatttactg
    10921 aaacactcgg atttgagatt agtacagaat cgctttatga caagctattt tctaaggctt
    10981 tggatggtga tccggactgt ggtggtttat tatcttatgg ataccattca ggagaaaata
    11041 tcacgggggt aaatgaaggt cgtccattat ttgtacgtac gccggatagt aagttcgatt
    11101 tggcaaattt catgagagtt catctttcta gtgcattcgg agctatgcgc ataggtatgg
    11161 agatattaaa aaaagagaat attaagattg ataaattggt tggtcatggt gggattttta
    11221 aaacaccaga agttggacaa aggattctgg ctgcggcaat ggaggctcct gttaccgtaa
    11281 tggaaactgc tggagaagga ggagcttggg gaattgcttt attagcttcg tacttaactg
    11341 ataaaaataa tttaactttg gaagaatatc tttcaactaa agtttttgct aaaagcgaag
    11401 gtattacaat cgagccaaca aatgaagata ttgaaggata tgctaagttt attgatcgtt
    11461 atgaaaaagg cttatccatt gaaaaagctt cggttgtcgt ttaaaaaaaa taggaggtta
    11521 ggtatgttag agcaattgaa agaagaggta tttcaagcga atctggaatt accaaaacag
    11581 ggattaatta aatatacatg gggaaatgta agtgcctttg attcagagag tggctatttt
    11641 gtcattaaac caagtggtgt aagttatgaa gcgatgaaag cttccgatat ggttgttgtg
    11701 gatttagatg ccaatgtaat tgaagggaag atgaatcctt cttccgatac gcctactcat
    11761 gctattttat atgagaaatt tcctgaaatt ggtgggattt gtcatactca ttcaacttgg
    11821 gcaacaatat gggcacaatc gggtttggat ttacctgcaa tgggaacgac tcatgctgat
    11881 acattttatg gaacggtacc ctgtgcgaga tttttgacac aagaagagat tgagaacggc
    11941 tatgagaaag aaacaggaaa agtcatagtt gacactttta agaagcgtga aatcaaagaa
    12001 cttgaagtac caggcgtttt attacatgga catggaccct tcacatgggg agaaagtgcg
    12061 aaagcagcgg taatgaatgc agttgttttg gatgaggtcg ctaaaatgaa tctttttact
    12121 cgtcaactga actcatttgc agaagagtta cctcagcgtg tattagataa acatttttta
    12181 agaaaacatg gtaaaaacgc ttattatggt caagctaaat aaagaaaaga gggaaaattt
    12241 atgttagaaa ttagaaaaaa agaattttgg tttgtggtag gatcacaaca tttatatggt
    12301 gaagaagctt taaaaacagt aaaaatgaat gcccaagcaa tagtaaaagg attaaatgat
    12361 agcggtaaac tatcgtatcc gattgttttg caagatctag ctgtgacttc agataaaata
    12421 actgaaatta tgaaagaagc caattaccgg gacgaagttg caggtgtaat tacgtggatg
    12481 cacacctttt ctccagcaaa aatgtggatt cggggaacaa aattacttca aaaaccttta
    12541 cttcatttag cgacacaatt caatgagagt attccttggg aaacaattga tatggacttc
    12601 atgaatttga accaagcggc tcacggagat cgagaatatg gatttatcaa tgctcgcttg
    12661 agaaaacaaa ataaaattgt tgtaggatat tggcaaacat ctggagtaca agatcaaatt
    12721 tctgcttgga tggatgttgc cgcggcttat aacgaaagtt ttaatatcaa agtagcccgt
    12781 tttggagata atatgcgaaa cgttgctgtt actgaaggcg ataaagttga agcacaaatt
    12841 caatttggat gggtcgttga ttactatggt attggtgatt tagttcaata tgtagatgca
    12901 gtaaccgatg gggaagttga aaaagtattt gctgagtaca aagatttgta tgactttgat
    12961 tatggtgact atgaaaaaga agtttgggaa gcgcatgtaa aagttcaagc tcgacaagaa
    13021 attggaatta gaagattttt agaagcaggg aattacaatg cctttacttc aaattttgaa
    13081 gatttatatg gtatgaaaca actccctggc ctagctgttc aacgattaat ggcagaaggg
    13141 tatggttttg ctggtgaggg cgattggaaa acagctgcac ttgatcggtt gatgaaagtc
    13201 atggcacata atgaaaatac tggtttcatg gaagattaca catatgaatt agcatcgggt
    13261 aaggaatcta ttctgcaatc tcacatgatg gaagttgacc ctacacttgc tgttaataaa
    13321 cctaaaattg ttgtttctcc attatcgatg ggtgatcgtg aagatccagc gcgattagtt
    13381 ttcgatggaa aagcaggagc gggtgttgtg gtatccatgg ccgattttgg gacacactac
    13441 aaattattaa ttaatgaagt agacctgttt gagccaacag aagcggcacc taaattaccg
    13501 gtagctcgtg tactttggga agttaagcct aatttccatg aaggcgttgg agcttggatt
    13561 gaagcaggcg gaggtcacca tacggttgta tctttgaatc tgactactga ccaaattcaa
    13621 acttgggcca aaatggttga tttagagttc gtaactatta aatagatcct aagaattggt
    13681 ttgggaaacc aggccaattc
//
LOCUS       DAPBBR010000065        13456 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPBBR010000065 DAPBBR010000000
VERSION     DAPBBR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.068"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..924)
                     /locus_tag="RD488_002249"
     CDS             complement(<1..924)
                     /locus_tag="RD488_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDT7658307.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGK"
     gene            1114..1383
                     /gene="rpsN"
                     /locus_tag="RD488_002250"
     CDS             1114..1383
                     /gene="rpsN"
                     /locus_tag="RD488_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7658308.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(1559..1921)
                     /locus_tag="RD488_002251"
     CDS             complement(1559..1921)
                     /locus_tag="RD488_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7658309.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(1932..3053)
                     /locus_tag="RD488_002252"
     CDS             complement(1932..3053)
                     /locus_tag="RD488_002252"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDT7658310.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(3069..3419)
                     /locus_tag="RD488_002253"
     CDS             complement(3069..3419)
                     /locus_tag="RD488_002253"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDT7658311.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(3549..5060)
                     /locus_tag="RD488_002254"
     CDS             complement(3549..5060)
                     /locus_tag="RD488_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7658312.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(5382..6734)
                     /locus_tag="RD488_002255"
     CDS             complement(5382..6734)
                     /locus_tag="RD488_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDT7658313.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(6887..7963)
                     /locus_tag="RD488_002256"
     CDS             complement(6887..7963)
                     /locus_tag="RD488_002256"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDT7658314.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            8159..9904
                     /locus_tag="RD488_002257"
     CDS             8159..9904
                     /locus_tag="RD488_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDT7658315.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(10184..10621)
                     /locus_tag="RD488_002258"
     CDS             complement(10184..10621)
                     /locus_tag="RD488_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDT7658316.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(10605..11978)
                     /locus_tag="RD488_002259"
     CDS             complement(10605..11978)
                     /locus_tag="RD488_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658317.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(12300..12788)
                     /locus_tag="RD488_002260"
     CDS             complement(12300..12788)
                     /locus_tag="RD488_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658318.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(12810..13412)
                     /locus_tag="RD488_002261"
     CDS             complement(12810..13412)
                     /locus_tag="RD488_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7658319.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         3853 a         2923 c         2446 g         4234 t
ORIGIN      
        1 tttcccagca ggaggatgtc cttcaactag ctgatgtgct tggatgacat gcttaagtga
       61 agcagacaga ttcattgaaa taaaaacatg aaaggctcct ttttggtagg ctttgattat
      121 gccagcaaag gcttctgcat ctagatattc ctttcttgga acaaacgatt cataaaagcc
      181 ttcctttttt tgccgcaaat ctagatctgg gaggtcattt aatgcaacat acctgccgcc
      241 tggtttcatg atctggatgc cggtttctcc tttgatactt cctttcgtcg catcgattac
      301 aaggtctgcc tgatcagcaa attgcagacc tggatttgtt ttatcataag cagcaaatgc
      361 tgaagctcct aattttttta ccttttcctc atttttactg gatgcactgg ttaagattcg
      421 gattcccttt tcatggagaa gctggatcag acttgacccg accgcacctg atgctcctag
      481 tatcattaca gtatctgtcg gctggatttc cgtcaaatgg ttgattagat tataagccgt
      541 aattcctggc gtgaccattc cggctgcttc ttcccaactc attttatctg gaatttttgc
      601 tacttttgct gatggcaaca cgacttcttc tccgtaagtc ccgccgactg catggacagc
      661 tactcgatca cctacatgaa cagttgtgac atctgaacca atctctgtca caataccagc
      721 gccatcatta cctggtacat aagggaattt caatgttcgt atctctttca tttctcctaa
      781 acgcaaggca acatcataag gattcacact gaatgctttt atttctacac gaacatgtcc
      841 agaaccgact tctctgggat gagcatcgat ttcttcaaaa acatcttgtg cttctccgta
      901 accgttaatt gcaaatcttc gcatggtcac catctccctt tttctttaag tttacgttta
      961 tgtctttatt ttgacaaaaa aaatgtcttt tcgttttggc gcatgattca aaacaaaata
     1021 gttgtctttt ttcgcgtaac gtgttaaatt atttatctaa aagcgtaaag attacgattt
     1081 acgctaataa aaaataattg gaggaatttg ttgatggcta aaaaatcaaa gattgccaaa
     1141 gcaaaaaaac agcaagaaac gattgaacgc tatgctgctt tacgccagga attaaaagcg
     1201 caaaaagatt acgaaggctt gcgtaaactt cctttagatg ctcgtccaga acgattgaaa
     1261 aatcgtgatt taatcgatgg acgccctcgc ggatacatgc gtaaattcgg gatgtcccgt
     1321 ataaaattcc gtgaattagc acataaaggt ttgattccag gagtaaaaaa agccagctgg
     1381 taatccaagt ctggctgtaa tgtaaaggag gagggcgcat ggaccactcc ttggatcatc
     1441 aaaaaagata cgttcgcttc ttctagcaga aatgctggta ctagaagcag acgtatcttt
     1501 ttttacgcac agctggtcct tttttatatg taaaggctgc atggttactt cgctatattt
     1561 atttagtaac aggagtcagt gcttcgatac ccacactaat tttcaatgct cggtcaactt
     1621 ctgccataat gggtcgatcc aaatggcaga ccttttcttt caatcttgat ttatcgatcg
     1681 ttctgatctg ctccaacagg ataacggagt ctctttctat tcctgttcca gtagctttga
     1741 tcccaatgtg agtcggaagc ttaggtttag ccatttttgc cgttatggcc gcaacaatga
     1801 tcgtcgggct aaaatggtta cctagattat tttgaataac caaaactggg cgtgttccgc
     1861 cttgctccga tcccacgact ggagaaagat cagcaaaata aatatctcct ctttttacca
     1921 taggatcctc cttattcttg atattctctt ggtatccgct gtcctaatcc gcaagccact
     1981 tcatagtgga tcgtacctaa ttgatctgct atatcctgca tagtgatttc tttgtctgca
     2041 tttttgccga taagcgtcac ttttgttccg acaggaaatt cttgaggcaa tcggatcatc
     2101 agttgatcca tacatacacg cccaatcgtt tcacagtagt tcccttctac caatagagaa
     2161 aaaccctgca tctttcgtgg ccagccatct gcataaccga tcggtatcgt tccgatccac
     2221 tctgcttcag gagtgatata tgtttctcca tagccgattc cttcacctgc tgggagtttt
     2281 ttgacttgaa tcaattcaga aaccagctca agtgctggct gcaatggata aacttccggt
     2341 agtgcgtgcc cagagggatt aagtccgtac attgctactc cataacgaat catattgccg
     2401 attgtttcat catgccataa agccgttgca ctattgctga catgtacata tcgaggaagt
     2461 tcgggaagtt ttttcagcac ttctataaag cgttcttttt gcagattcca atatgtatca
     2521 tctgcctgat ctgctgtaga aaaatgggta aataaacctt cccattctaa tacacgactt
     2581 tctttgatga atgcagctgc ctcttttact tcttcaggtg tacaaaatcc gatacgaccc
     2641 atcccagtgt ctgcttttag atgaatcgaa agaggcgtct ctagcttact tttctctaaa
     2701 acagcagctg ctgcttgcaa ccattcccgt gtacctgcag ttactgataa atcatgagca
     2761 acagctacag tcagtgcgtc gtaaggaacc atattcaaga taaggatggg ctgagtaaat
     2821 ccagcttctc tcaactcgac tccttcatct aaatttgaaa cacaaaagcc cgaagctcca
     2881 cctgcaactg ctgcctcagc tgtttcaata gctccatgac cgtatccgtt cgcttttact
     2941 actgcaaaca attcttttcc ttgcggaagt cttgcaactt catttgctac attttcagtt
     3001 atagcttttt tatgtatcac tgctttcgtt gggcggtgcc aagcgacaac catcgttttt
     3061 ccttctttct agtcttccaa aataatttgt gcaaaagctg tttcatttgt atgagtaata
     3121 ctgacccata cattgccttc atgaggtgaa cgcgtcacaa caggctgacc attttcattt
     3181 tttaaaatct cgacatcttg aaaggtaact tttccgatcc cagttcccca agctttagag
     3241 aaagcctctt tgcaagcgta acgcccgcct aaaaattcta cttggcgatg aaaaggcaag
     3301 gactggaata gtttcatttc atcagaggtc aagattcgtg caatgaattt tggtttttct
     3361 tcgatcagcc gagtgatcct aggaagttcg actgcatcga tcccaattcc ttttatcata
     3421 tgcttttctc ttttcaataa atttagaaca ctctcattct accaaattat aaccattttg
     3481 ccacaaataa gtccacaaat aacaaaaatg aaagtttctc ttaaaaaaga gaaactttca
     3541 ttttatgttt aatcgttatt tgaacggatt acaaatccgc gttttttatc attgtgacgt
     3601 ttaccgccat ctttttggct gttattattt ttgctataac cgccttttga tttgtttcca
     3661 cgataattac cgccgtcacg acgattacgg ttgtttccgc caccacgttt gccattttta
     3721 ttgtatcctt ttttctgcat tggcaatggg cgttctggtg tgatcttcac tggcactgca
     3781 tcagctggat cttttgctgt cgtttttagc aaaagtgcaa ctaaatcttg tgcagaatat
     3841 tcttctaata atttatctgc tgtttgcagg tatttatcta gaccattttc tgcaagtttt
     3901 gtttcgattt gttcaactgc agcacctaat tgacctttga atgcttcttt ttcggttggt
     3961 ggacgtaaag tcgtcatccg ttttttcgtc aagttttcaa tcacatgcaa gtagtccatt
     4021 tcatttggtg taacgaaagt cacagacata ccgccttttc cggcacggcc tgtacgtccg
     4081 atacggtgaa cgtagctttc tggatcttga gggatatcat agttgtacac atgagtgaca
     4141 cctgaaatat ctaatccacg tgcagcaacg tctgtcgcta caaggatatc taaatgaccg
     4201 ctcttaaatg aacgcaatac gctcattcgt ttttgttgag acaaatcgcc atggattcct
     4261 tctgcacggt aaccgcgtgc ttctaatccg cgtgccaatt cgtctacacg gcgttttgta
     4321 cgtccgaaga cgattgttaa ttcaggtgtt tgaacatcaa acaagcgagt catgatatcg
     4381 aatttttcgt attcttttgc gcggacatag tattgatcga tcaagtcagc tgtcatttct
     4441 ttcgctttga tcttcacatg atgtggattt ttcatgaatt taacgccaat attcttgata
     4501 gctggcggca tcgttgctga gaaaagtaat gtttgtcttt gatcaggaac ttgtgaaatg
     4561 attttttcga tatcttccaa gaagcccata ttcaacattt catctgcttc atccaaaact
     4621 aatgtttgaa cggttccaag tttcaatgtg tggcggttaa tgtggtcaag catacgtcct
     4681 ggtgtaccca caacgatatg tggacgatct ttcaagccac ggatctgacg gccaatatct
     4741 gctccgccgt aaacggcttg tacacgtact tttttgtcgc gccctaaacg atataattct
     4801 tcttgtgttt ggatagctaa ttcacgtgtt ggtgcgataa ctaaaccttg taattcgtga
     4861 cgatctggat cgattttttc taacattggt aatccaaatg cagctgtttt ccctgtacct
     4921 gtctgtgctt gtccaataac gtcttttcca gctaatgcta gtggaatcgt ttctgcttgg
     4981 ataggcgttg cttcttcaaa accagcgcgt tcgactgatt tcaacaattc tggtgataat
     5041 tctagttctt taaatttcaa atgaatcctc ctatatggtt gttaactgag gatgtagctt
     5101 ttttgctacc ccgtcgattt gttcggtcaa agtgtattgt ttctttttga cagtggccac
     5161 gcacgttttt atccattctt agcccctgtg gcaccaccga aaaatcactt tgcgaagttt
     5221 aggcattaga aaagccaaac gggtcgcgtt cagctttatc attattatga catctggctt
     5281 caacaagttg tttctatggc aaaaccagtc caatttctct tcatctttcg gcaataggtt
     5341 attctaacat agtttttcgt tttctgcaag tttacagatt tttatttcat ttgctgaagt
     5401 tgttctacca cttcaaataa gcccatgctg ttgctgcctt ttagcataat actatctgtt
     5461 gctgcaagat tttgtttgat agcatcaatc aatttattct tttctttttc aaaatagaac
     5521 acaggtagtt gggggtattt ttggttcaat tcttctttta gtgcatgcat ttgttcccca
     5581 taaaggaaaa tcatggcgaa tttctcagga tcgatatgtt cactcatttg cgcatgcata
     5641 tttaaagact ctttccctaa ttccagcata tctgctaaca cagcgattct gcgtcctttt
     5701 gttggcagat ttttaaaagt atctaatacc agtcccatgg ctgttggatt tgcattgtag
     5761 acatcgctca aaatagctgc accatttcct gccgttagcc attcggttct gttttgagtg
     5821 atagaaacat gggcgagccc ttggcgtatc tcaggtatgg acagtccaaa gaagcgcccg
     5881 atcgtatacg caatcaaagc attcgttaca ttataacttc caggcagcgg gatcgtaaat
     5941 gtttctcctt ctactacaaa atcggtttgt gcttttcctt ttgctgtcac ttccgcatga
     6001 acatcgccat ttccaatacc gaatgttgtg actgtttgta ctaatgttgc cgttaaaggt
     6061 gtcagcaacg gttcatctgc gggcacaacg agtaatccgt ctgatacaag tccgtcagtg
     6121 atttccattt tggctttagc gattccttct cgcgacccaa gattttctat gtgtgcttca
     6181 ccgatcattg tgattgctgc agcttttggt tgagccataa gtgaaagttc cgtgatttca
     6241 ttggcgtgat ccatgcccat ttccaaaacg atcttttctg tatcttgggg catgtgcaaa
     6301 atcgtgtaag gaagaccaat attattgttg taatttcctt gcgtcttata tgttttgtat
     6361 ttttcagaca agacagacgc ggttagatct ttcgtggtgg ttttaccatt gcttcctgta
     6421 attgcaacga cttctgcgcc tactttttcc aagtaatagg ttgccaattg ctgcatggct
     6481 ttcaaaggat ctgctacagg aataactgga aaattttttg gagcttgttc aacaggcaag
     6541 ctccaaaatg aagcagatgc tccgtttgtg atcgcttgct ggataaattc atgtccatct
     6601 cgcgtaccag caagaggaac gaataaactt ccttcggtta tcttccggct gtcaaattcg
     6661 acattggtaa tctttgtcag tgcagagcat tcgctgccca cggcttgtgc aatttcttgt
     6721 attgttagat tcattgagat ctctcctaaa aaaggttgtg aaaaaagcgt ttggcctaaa
     6781 cggcgggttc gcatgactct cacttccaag taaatttctc tattcgtatt tagaagctag
     6841 aatgaacgcg gttacgcaat cactccagcc tcttctttat ttctctttat tcattttttt
     6901 caaaaaaaga ttgacgctga tggtatcgat tcattcctaa ctggatcagt tcttcaatca
     6961 aatcaccgta tttcaagccc atattttccc ataagagtgg gtacatactg aactccgtaa
     7021 atcctggcat agagtttaat tcattcagga ataattcatt tttatttgtc aaaaagaaat
     7081 cgcaccggct caatccgctt ccacctaaca tcgtgtaagc taacttcgcg tactcttgcg
     7141 ctttttgata aacttcttct ggcacttcgg ctggaatctg catttcgatt ttattattga
     7201 tatattttgc ttcataatca tagaatgcta cgtcttttac gacttcacca ggcaaagtcg
     7261 tccgaacgtc ttcatttcct aatacagcaa cttcgatttc gcgcgcttca attccttgtt
     7321 caacgattgc tcgagaatca tactgatagg ctgttgctaa agcattttgc agctcttctc
     7381 ggttttctgc ttttgtaatg ccgacactag aacccatatt cgccggtttg acaaacatcg
     7441 gataaagcaa agaaccttca cattgatcaa atactttttt aggattttct ttccattgat
     7501 tcttaagtac tggtacataa ggaacttgcg gcacaccagc agcttgtaaa atatacttgg
     7561 tcatgatttt atccatggca catgcactgg tcaatacgcc tgcgccgaca taaggcatat
     7621 tcaatgtctc taagaagcct tggatcgttc catcttcccc gtttggccca tgtaaaactg
     7681 gaaaaacgat ggctccttct tctttgattt cgcccggatt gatcactttt cctgtaaagc
     7741 cttcctctgt ctgtccactt gggtcccatg aaagatgcaa gacatctttg ctggcaggtt
     7801 tttctgttag taatggacct ttgacccatt gtccttcttt tgtaataaat acgagttgaa
     7861 cttggtaata attataataa atggcattta aaactgaaaa tgcggaaaga atggacactt
     7921 catgctctgc gctgcgtccg ccatatagta aagtaatctt caaaagattg tcctcctgta
     7981 ttctaaatcg ttcagtgatt tactctcata ttttagcaca aaacaaaaat aaacgaataa
     8041 cttatttata aaaaaacgag ccagcttcta aaagaacgag cgtcatttat tttttgtcag
     8101 ctagattatt tgtcccgttt tttataaaaa gttatgataa agaaaaggag ggatgatgat
     8161 ggcgcaaaca aatccacgca gccgcttggc agaaatcatt cgagtgttca tcaattacaa
     8221 tgtagtgcca aactttgtac agcaaaaaaa tcccgaacag gtaaaaaaag cctttgaaga
     8281 actaggcccc accttcatca agataggaca gatgctttct gttcgagaag atttgctttc
     8341 ttctgccttc actcaaacat tcaaaacatt acaagatagt gtacctagcg acacattttc
     8401 aacggtcaaa aagacgatcg aaacagaact ttctctttca ttatcagata tattcgatga
     8461 tttttcaaaa tcgccttttg cctctgcttc tatggggcag gctcatcgtg ccaagctgaa
     8521 gaacggtgac gcggtagtcg ttaagatcca acaccctaac atcgccgaag agatccgact
     8581 tgatcttcaa ctatttgaac gagcgatccc tttgatcaaa tacattcctg aaactagcgt
     8641 agttgatcta aaaggggtac tccaagaagt aaaacgttcc ttgatcaatg aaatggactt
     8701 cttaaaagaa agtcaaaatg gcgaacaatt ctatcaaaag aacaatggct ggaaagagat
     8761 ccgcagcccc aagatttatg acgctttttg ttcgaaaaaa gtgatcgtga tggaagaaat
     8821 gtctggtaaa aacttgaatc atttaatgaa cgccgaaaac aaaactgaaa cttttatcac
     8881 tggaattcaa aacaagcagc tgaaacaaga agttgcaaag cttttagttg agaactttat
     8941 gaaacaggtg tttgatgatg gttttttcca tgctgatcct catccaggga atctgctatt
     9001 ccatgtacta acaaaagaag aacagacaca agctagccga aaaactgaaa cagtccatga
     9061 aaaagagttc ggttcctttg cttttcgagc ctccacttct gcagaagacc ctgttgcgcc
     9121 atataccatc aactacatcg attttggtat gatggggcat ctttctgcag gacttaggca
     9181 aaaactcaca caagccgttt tagcgctgta tacgaaagat gcttatcgaa tcgaaaaagc
     9241 ggtccttcga ctttgtcagc aagaaggctc gtttgatgaa agtcggttcc accaagaact
     9301 gacaagtttt cttgaacagt attatgattc tcctattgat gaaatcaact tgcaagaagt
     9361 attcacacat gtcgtgacga tttgtcatca aaataatctg cagttcgatc gtgatatcac
     9421 gcttttgctg aaagcatttg ggacattaga aggggtgatc cgcgtcctcg atcctgaagt
     9481 ttccctcatg gaagtcgctt cgccttttgc tcaacattat tttctcactc atctggatgt
     9541 agaagataca ttgaaacaaa gcggattaga cttattggaa gggatgaagg ctgcgcctaa
     9601 gatccctcaa cagctccacc atctattaga aatgtggact tcgggacaag gaaaagtcaa
     9661 tttggaattg aaaaagcaag acaaattatt gagcaggatc gaaagtatga tcaatcggct
     9721 tgttttcggt atgattttag ctgcattgat cgtagggtcc tccctgcttg tccaagcagc
     9781 acctgtagaa aacgcagagg tcgtttcctt attagggata tttacgtatg ctattgccgc
     9841 attcgtcatt atttttttgg caatcgatgc attgatccaa atgtataaga agaggaaaaa
     9901 gtagaaaaag gttgtgacag aaagaatcag cttcaagaaa taagaagggg ttttacataa
     9961 attgtttctc aaatttttgt gaaaattcgg cttatttttc gaagaggcta cttctgaaac
    10021 accgagaata aaaaatgtga aaaagctgtt ctgcacccag taataagaac aatcaaaaag
    10081 ggaacatgga acacatttat cctgtttccc tgttcccttt ttgatgtatt cgagcataaa
    10141 taaaatacct tcgttaccta ctatcttctg tacttggtaa accttagtca attgcctttt
    10201 ttaacgcttg acgaaaagac atatgatctt tctccgtaaa gggttttgga ccctttgtcc
    10261 ttatgccagc ttttcttaac tttccactat gataacgttg ttctagaagc gtgccgatat
    10321 tcgcttcgtc aaattctttt ccagagtgat ggaacactcg cacacccttc ggcaatacaa
    10381 gtgaagctaa accataatct tgcgtgatca aaaagtcatt cttcttaacc ataccgacga
    10441 ttttataatc cgcactatca gctccgcggt ctacgtagac gatttggaca tgattagcgt
    10501 attctttggt cgtataatgg tccacactgg tcacgataac cacgtcaaga ccataggatt
    10561 ctcctaattt tatgacatct tcttttactg gagaaccatc tccatcaatg aatagcctca
    10621 ttctttttcg ccttcttcca taaatgataa acagttacta atccgctcag taaaagacca
    10681 acattgatcc attttgccaa gataagcagt tgtacacttt ctatcggcac tgattcatgg
    10741 ttcagcgtga tcaataatag atggattggc tctcccattt cttttgctaa aacaaacaaa
    10801 agcgtcatca ataaaaactg gtggatcaca ctccctttat tttgagtagt atacttgaca
    10861 acgatccggc gatccattgg aatagctgta tcagtttgat aatattcctt atttagccag
    10921 ctgcctgtta ctacgtgcca gaaactaagc agaaagacac ctatcgcaaa accatttgga
    10981 atcaagagga ccaataaaga agaactcagt ccaagcaatt gcatagccaa tggagaccat
    11041 gttaaacgtt tcaaaatcca tggtccgact atttttgctg caatcaagcc tgctgcataa
    11101 ggcaaataca taaaaatcga aagtttttct aatccgtaca gtatgccaac ataaaaactg
    11161 ctaaataaaa aaaggaaatt ccctagcatt ccatttagaa aagtaaacag atttagccag
    11221 cttggcaact tccattcctt cttctggtgt cctaaaacaa acacgaacaa gatgaacagc
    11281 agcaagaaac cataaatagc aagatcaaaa agcctttcat cgaataacaa tcgggcattt
    11341 ctcaaaagaa acaataagcc aaagaatatc aaaaataaaa caagctctcg cgtagctacc
    11401 agatttcttt tgatgtcttt gaaatccagt tcgtaacgcg gataatgact aaccgtatgg
    11461 taggccatga cgtaaaaaag tgtataaata gtaaagcttg ctgcaatctg agtcggtgca
    11521 ggcaactcaa tcgcttgata caggagaaat agccagatag ctgcaaataa gtactttttc
    11581 ccatccatat tgataaaacc ttgcgtcttt tcgtgaaaat tgaccgtggt attagcaggt
    11641 acaagccatg ctgcactcag ccctagcaaa acacttgaaa aataaaataa aggaaaataa
    11701 aatacgccta atattccaag caatgaacca gcaccaccaa tcagcagagc gatcatcagc
    11761 aacgtgtaac tatctagacc aaatcgtaga ctgttgacta aaaatagtcc agtcatccga
    11821 aaggcataaa acagcgtaaa tggcaaaatc gtcagccaat tatgcgagtc tgttagtccc
    11881 aaaaataaaa gataaggaat aaaaataacc gtgttactta agataaaggg cgttgtttgt
    11941 gtaaaattac gcccaaatcg tttgagtttt tcgaacatga caatggctcc ttaaacagtc
    12001 ttataactaa tctgctcttc gattttagca ttaaagggga aataaaccaa ttttacagaa
    12061 tatattcttg taaaaaaaaa tacagaaaga agcataagct tctttctgca tttttacggt
    12121 acttgattac tcaagcagac aagcccttct ccacaaaagt cttgcccgac acccctgcat
    12181 ccggcaggtg ataaagatag aaatcaatta tcctgtgcct ccaaaatcaa ttaggagctc
    12241 tgtaaaccag agtccttctc gacccgtcgc ataaatttac tttaacacag ttcctatgtt
    12301 tatgcgagag cttttttcat tttataatcg accatttgaa atccttgacc gatatctgaa
    12361 ataagttctt ctgtaatctc aaatccttca tgcttataaa cctcgattgc ttgatgattc
    12421 ccctgattca ctcgcaaaaa gatctctctt tcctttgttt gcgcagcaag ttcttcatac
    12481 cagcgaaaaa ctgaagaagt caatccttga ccacgtactt tatttagcaa atataattta
    12541 cttaaataaa tttttccatt tatctcttca taagcagtgt aaccgacagt cttttcttcg
    12601 ctttttaata aaaagtagga cacaccttct gtcagttctt tttgaatctg tttttttgac
    12661 tgataagttt tcagcatgta atccacttgt ttttgaccaa tgatcggcac aaaagcttcc
    12721 ggccatactt cttgtatgac tgccatcagc tcatccagtt cattttctgt tacttttatt
    12781 ttttccatac acccacgtcc ttttttacat tataaatgac cttgcgcttg atggaataaa
    12841 aagagcatga tcatgctata cacacccacc gaccatggtt tcaagaaaat cacaatctgc
    12901 ataaattccc taaaagataa tttcgtcaaa ccagctacta gacagatcaa gtcgtctggc
    12961 gcaaagggaa gcagcaaggt aacaactagt acttttttaa tatctttcgt ttttcttgtc
    13021 agcaattcat caaatttctg atactttttt ggcgataaaa taagctggac aaaggctacg
    13081 ccatagtaac ggacaagcaa aaatccgatt gcttccccaa tcactaggcc aatacaacta
    13141 tataaaagcc caaatccatt gccaaacatc agcatgcccg ctactgagga gatccctccc
    13201 ggcaaaatag gaatgatcac ttggatcact tgcaacagaa caaatatcat cactgcatac
    13261 ttgccaaatt gctggataaa cgcttgcaaa gacgtgctcg atcgaaaaat cccatgatga
    13321 taagcataaa gaatcaacac aaagaaaaaa aacagaccaa taatgggcat gatctgaaga
    13381 catttttgta aaactgatcc ttttttagac atctatattc cccacatctt ttttcattta
    13441 ttaaaactgc ctcctt
//
LOCUS       DAPBBR010000066        13156 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPBBR010000066 DAPBBR010000000
VERSION     DAPBBR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.069"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..942
                     /locus_tag="RD488_002262"
     CDS             <1..942
                     /locus_tag="RD488_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7658320.1"
                     /translation="NRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWK
                     EKVDVSTAGNKKGTIIVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEP
                     DASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKK
                     APNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQYHGTADENGNFTVKVPKLEAGT
                     KVIVTATDESGNTSEPTDVVVSSNTKDSGKNDNKGKTDNQGSNSNQDKNRGKSQSSKV
                     FPKTGEIDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1083..2426
                     /locus_tag="RD488_002263"
     CDS             1083..2426
                     /locus_tag="RD488_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7658321.1"
                     /translation="MEKIVIIGSNHSGLAAAQFLNLSDSNYEVILIDKKSEISYLECG
                     TALFIKREVSNLKDLFYQNRRELNSKIKKLFLETVADKIDIQNKKIICVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GKEKIEKIVTTRDNKYAMDMVIQAIGFLSHSPIGKKEFLRDVSGAYLTDEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQNFTPSGSQFTNGFSIFG
                     HNFYAAGLNLKTARLLNKSIDYIEIEDYIRPIFSKKNSIVKLRISFEKKAKRIVGVQF
                     YSQEDLSGLLTMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNSGA"
     gene            2537..3988
                     /locus_tag="RD488_002264"
     CDS             2537..3988
                     /locus_tag="RD488_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDT7658322.1"
                     /translation="MKKSLKLASAVLLMSHLLIATPFHVLASENSTYKIAKERTKTTE
                     MSNSDVTAESSELLTTSSSESSTTLNAESSTTSSSESSMTSNAESSTTSSSESSMTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TSQQIESTETFQSQPVLSGNEEIHFDKNESVENFIMKIGDSARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGSFVIMVTNEDLGNGTLYKTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNGL
                     IKTYDLTDYAKEVQGPQMNKNGYQIPIHNYSISSLFGNRGDEFHRGLDMAAAQGEPIH
                     AVKAGKVIKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVVQGQMIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGN"
     gene            4406..4621
                     /locus_tag="RD488_002265"
     CDS             4406..4621
                     /locus_tag="RD488_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658323.1"
                     /translation="MNQGIADIKLIKEVLQESTANAVASGSGISLSTAKKLKSGERNV
                     EKLNLSDAIKITEFAIKNRHVKIEIWK"
     gene            complement(4707..5618)
                     /locus_tag="RD488_002266"
     CDS             complement(4707..5618)
                     /locus_tag="RD488_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7658324.1"
                     /translation="MKIKIERNQKEKNQKKNKERVISVGKHRKMVLALWLLLSCSLSF
                     GIYRNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALSQDMVRADIPTSSEVQSIKILDVEKHSEEFIVSFLVEQQITEGKKTQ
                     SISSAYRVTIFEDENGSHIVTSLPTMIAKPEKAKYESKQIGIESDIDAKTTEEVTDFL
                     ETFFKLYPSASEKELEYYVENKAVQPINSNLKLVELVNPTFKLKGKEIQGEIFVKYLN
                     NTTKVSNIFQFTLTLQKVKNWKIIDIG"
     gene            complement(5637..6641)
                     /locus_tag="RD488_002267"
     CDS             complement(5637..6641)
                     /locus_tag="RD488_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7658325.1"
                     /translation="MNVKKLSIISLTILTLSFMVVLMCVGLLFGEDSEGSNSSGASSG
                     GSNVSEEVLKHRAMVEKYAKESNISEYVLILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVTKNGKKHNFALA
                     ESFSKEKSSGQKVDYPNPIAIKKNGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGASPETGFDCSGLTQWCYAKVGLKLPRVAQDQYNAMTHIDVKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            complement(6638..8761)
                     /locus_tag="RD488_002268"
     CDS             complement(6638..8761)
                     /locus_tag="RD488_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7658326.1"
                     /translation="MKKKLLRIVGIIAISLCTILLLLSLIGTLAEATGLVDDTVKSGN
                     LYSQYSLDNYQLDFFVDSSWGWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQVSGFYFGFLLLMILALGVYVAYI
                     GLLKREATKAVRAVINFVTIFLLSGSFIAYAPTYITKINNFSSDVSEAALSLGTELVV
                     PNSESKGKGSVDLIRDSLFSIQVRQPWLLLQFDDSNIEEIGEDRVNKILSVSPDGNKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRIMRKPHMLMNRKLR
                     QLNRNVIRTLAFGGGAAVGHKLAKEQSKSKFKPSGSSLRKNSRLPNDHEVPSESTKEN
                     PVSNNKKQSRMNLAGRKMGKVLDTQALVKDKTKQVRDQVRNTPTNLKYNFHKGIEKTK
                     KAPKEFKRGLVQEKANRAELREKQRQHRDEKMAEKRKVLNETGNRHKKRRENVSIKPE
                     RQPQKDRTPKKEAPKQIVRVNPNPEIKRKLTSHEIVSKRISQPSSKKNSFQQVKQRST
                     LPKRTNQKVQKRMNPRPKSRSGEKK"
     gene            complement(8766..11216)
                     /locus_tag="RD488_002269"
     CDS             complement(8766..11216)
                     /locus_tag="RD488_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7658327.1"
                     /translation="MMYPIKYIENNLVFNQDSECFAYYELVPYNYSFLSPEQKYQVHD
                     NFRQLIAQNREGRIHALQIATESSIRATQERSKKEITGRLKEVAEQRIDLQTDALVSM
                     IGDSQIDYRFFIGFKLIVTDEEVNLKSLKNSFLSGLQEFVYGVNHHLMGDFVSLSNEE
                     IRRYTKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKRKLKS
                     ETLIKRYDLLRPSRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQ
                     QQQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSV
                     DELETMLDQSKESMYKLSYVVRVSAESLDELKRRCDEVFDFYDDTNVKLVRPFGDMMG
                     LHEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKP
                     ALASQGVKGSITNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWK
                     ETLPEITDEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEK
                     FPVLRKAIRTVTQSEQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGS
                     ITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNRE
                     IFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLNERLKNNIGL
                     KFAFRSTDIHEIKKTLEFFGLDQEDESNQKRLRDLENEQCLMQDLYGRVGVVQVHPVF
                     EELFHAFDTRPPVQKRME"
     gene            complement(11200..11589)
                     /locus_tag="RD488_002270"
     CDS             complement(11200..11589)
                     /locus_tag="RD488_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7658328.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVAWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWNEAITLVRSVNDVPD"
     gene            complement(11672..12396)
                     /locus_tag="RD488_002271"
                     /pseudo
     CDS             complement(11672..12396)
                     /locus_tag="RD488_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12445..12948)
                     /locus_tag="RD488_002272"
     CDS             complement(12445..12948)
                     /locus_tag="RD488_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7658329.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFSPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPIGEVALEIQHAFFNSFEEMVEH
                     VDDIICYPDCNDMSDVAYYLIEETGALGEVPTHLQNYIDYEAYGRDLELEGNYLVTNR
                     GTFEFIG"
     gene            complement(12960..13121)
                     /locus_tag="RD488_002273"
     CDS             complement(12960..13121)
                     /locus_tag="RD488_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658330.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     NLFNRIVGA"
BASE COUNT         4334 a         2472 c         2229 g         4121 t
ORIGIN      
        1 aatcgttcta atgcagataa atacaatccc gaaggacaaa aagtgactac agacttaaac
       61 aaagagccag atgcatctga gggaattaag aacaaagaag atttaccaaa aggaactact
      121 tatgcttgga aagagaaagt agatgttagc acagctggaa acaaaaaagg cactattata
      181 gtgacatatc cagatggatc atctgatgaa gttgaagtag acgttacagt gacagatact
      241 cgttccgatg cagataaata caatcctgaa ggacaaaaag tgactacaga cttaaataaa
      301 gagccagatg catctgaggg aattaagaac aaagaagatt taccaaaagg aactacttat
      361 acttggaaag aaaaagtaga tgttagtaca gctggaaaca aaaaaggcac tgttgtagta
      421 acatatccag atggatctaa agaagaagta gaagttacta tttctgtagt agataaaaaa
      481 gcaccgaata aacctcaagt tgatcctatt acagagggtg accaaattgt tactggtaaa
      541 actgaaccaa atgcagaggt aacagttaca ttaccagacg gaagtcaata ccatgggaca
      601 gctgatgaga atggtaattt tacagttaaa gttcctaaat tagaggcagg aacaaaagtg
      661 atagtaactg caactgatga atctggtaat actagtgaac ctactgatgt agttgtttct
      721 tccaacacaa aagacagtgg aaaaaacgat aataaaggta agactgataa tcaaggtagc
      781 aatagcaatc aagacaaaaa tagaggcaag agccagtcct caaaagtttt tcctaagacg
      841 ggagaaattg acagtaatat ctttactatt agcggtggtt taatattgtt aggaacttta
      901 ggattattag ggtataaaaa tcgaaaaaaa gagaatgaat agaaaatcaa tttcttaagt
      961 cttctctgag aagaggaaga atctttttct tcctcttttt gtttttttat gatgagaaat
     1021 aagtgttagt taaagatgag tatacttttt atagattata gaagaaaaaa gaaagtgatt
     1081 gagtggaaaa aatagtaatt attggttcaa accattcggg gctagccgca gctcagttcc
     1141 taaacttaag tgattcaaat tatgaagtta ttctgataga taaaaaatca gaaattagtt
     1201 acttagaatg tgggacagcg ttgttcataa aaagagaagt tagcaattta aaagatcttt
     1261 tttatcaaaa tagaagagaa ctaaattcta agataaaaaa gttgtttttg gagacagtag
     1321 ctgacaaaat tgatattcaa aataaaaaga ttatttgtgt aaaaaaagat ggtacaagat
     1381 tctctcaaga atatgacaaa gttatattag ctacaggttc aaagcaaatt atgttagata
     1441 taccggggaa taatttagct aatatttttt cgataaagaa ttttccaaat gcaaaagaga
     1501 tttttaaagc tttggatgat agtactatta aaaaagtagg aattattgga gcaggatata
     1561 ttggagttga aattgctgaa gctataagaa aaagagggaa agaagtgtat cttttcgatg
     1621 ttgcagatag agtgttgtcg acctattacg accgtagttt ttcagataaa gttgaagaaa
     1681 tactatcaaa aaacgggata catctttgtt tatcagaaag tcctaaaaag tatttaggaa
     1741 aagaaaagat tgaaaaaata gtgactacaa gagataacaa atacgctatg gatatggtca
     1801 tacaagctat aggattccta tctcatagtc caatagggaa aaaggagttc ttgagagatg
     1861 ttagtggagc atatctaacg gatgaatacc aacaaacaaa tataaaagac atatatgcta
     1921 ttggagattg tgctacaact ttttttacat caattaatag aagtagcgtt gatttttcta
     1981 tctctaatgc tctaagaacg gcttatattg caactcaaca tattaacaat caaaatttta
     2041 caccttctgg ttcccaattc acaaatggat tttctatatt tggtcacaat ttttatgcag
     2101 caggtttgaa tttaaaaaca gcacgcttat taaataagtc tatagattat atagaaatag
     2161 aagattatat tagaccgatt ttttctaaaa aaaacagtat tgtaaaatta agaattagtt
     2221 ttgaaaaaaa agcaaagaga atagtaggtg tacaatttta tagtcaagaa gatctatctg
     2281 gattattgac aatgttctct cttgctatag aagagcaaat tacattagac aaattgaaaa
     2341 tgttagatta tttatttcat cctagtttta gtcaacccta taattttatt ttaaaggcag
     2401 taacaggatt aaatagtgga gcataatcgt tactaaatga aatcaagaaa tatactgtat
     2461 tactcaattc attgaaaata tttgtcatat tttttaatag aaaacactat taaagaaaaa
     2521 aagagaggta aatcaaatga aaaaatcttt aaaacttgca tcagcagttc tattaatgtc
     2581 ccatctcctt atagcaacac ctttccatgt gttggcaagc gaaaattcaa catacaaaat
     2641 tgcaaaagaa agaaccaaga cgactgaaat gagtaattcc gatgtaacag cagagagtag
     2701 tgaacttttg acaacttcat caagtgaaag tagtacgact ttaaatgccg agtcttcaac
     2761 aacttcatca agtgaaagta gtatgacttc aaatgccgag tcttcaacaa cttcatcaag
     2821 tgaaagtagt atgacttcaa atgccgagtc ttcaacaact tcatcaagtg aaagtagtac
     2881 gatttcaagt accgaatctt caacaacttc aagtagtaca agtgaaataa cttcttcgaa
     2941 agttacaaag ccaaaccata tagagtcttc aaaaaaggaa gcgccaaaaa cggaaggaca
     3001 aacaaaaact ttttcgacat cacagcaaat agaatcaaca gaaactttcc aatcacaacc
     3061 agtactatct ggtaatgaag aaattcattt tgacaaaaat gagtctgtag aaaattttat
     3121 tatgaaaatt ggtgattctg cgagaaaaat tggtcagaaa tatgatttat atgcttctgt
     3181 tatgattgca caagcaatct tagaatctgc cagtggtcaa agccaattag ctcaggcacc
     3241 gaattacaat ttatttggga taaaaggaac ttataatgga agctttgtca taatggtaac
     3301 aaacgaagat ttgggtaatg gaacgcttta taagactcaa tcgaaattta gagtgtatga
     3361 aaactatgag gaaagttttg aagattatgc caaattatta actaagggaa ttagtggaaa
     3421 taaagatttt tatgccggag cattaaaagc taatagtaaa acatatcgag aagcaactaa
     3481 attccttaca ggacggtatg caacagatac tcaatactat ttaaagctaa atggattaat
     3541 taaaacctat gatttaactg actatgccaa agaagttcaa ggtccacaaa tgaataagaa
     3601 cggatatcag atacctattc ataattattc aatatctagt ttgtttggaa atcgtggaga
     3661 tgagttccat cgaggacttg atatggcagc tgcacaaggt gaaccgattc atgcagttaa
     3721 agctggtaaa gttattaaag cagagtttca ctattcttgg ggaaattacg ttgttataca
     3781 acacgaagat ggatcaacag cgttatatgc tcaccaacaa caatacttag taaaaactgg
     3841 agacaacgtt gtgcaaggac aaatgattgg ctatgtagga agtactggga atagtacagg
     3901 accacacctc catttggaaa tttgcaaaga tagtagtctt tctcaaagca tgttagttga
     3961 tccgaaaacc ttattatttg ggaactaaaa agaaaaagag cattttatta gaagtatgga
     4021 ttagggaata tagtagtagt gggctctaaa gattatgaaa tctttaagag ctctttttaa
     4081 gacgattgtt taaaacgaat taaccaagta ggagctttcc tagaatttat aaaattatag
     4141 tttcttgtat gacatgtata tagcatgcta aaataccaat aaataaggtt taagataaac
     4201 gcaaaaagtc gaaaaattaa cacttatttt gtgatattaa ttttaatttg caaaacaagc
     4261 tatatggaaa aagtttaaac tttttctaga gtccctatta ctagttaaaa agaccactgt
     4321 agtcctctga taaatcatcc taaagaccac agtagtcccc ttaaagtttt tccaaattaa
     4381 ctatctgaga aaggagagaa gatttttgaa tcaaggaata gctgatatta aattaatcaa
     4441 agaagtttta caagaatcta ccgcaaacgc ggtagcatct ggatcaggga ttagcttaag
     4501 tacagcaaaa aaactaaaaa gtggcgagag aaatgtagaa aaactaaatc tttctgatgc
     4561 aataaaaatc actgagtttg ctattaagaa taggcatgtg aaaattgaaa tttggaaatg
     4621 acggatacaa ctattatagt tttgtttttt ctaagtatca tatttatgaa tatacttttg
     4681 ctaaacattt aattatagat taatttttat ccaatatcta taattttcca attttttacc
     4741 ttttggagag taagggtaaa ttgaaagata ttgcttactt tagttgtatt attaagatac
     4801 ttaacaaaaa tttctccttg aatttctttt cctttcagtt taaaagtagg attaaccaat
     4861 tcaactaatt tcaaattact attaattggc tgaactgctt tgttttcaac atagtattca
     4921 agttcctttt ccgatgctga tggatacagt ttaaaaaagg tctctaaaaa atcggtgact
     4981 tcttccgtgg ttttagcatc aatgtcagat tcgattccta tttgttttga ttcatatttt
     5041 gccttttctg gctttgcaat catagtaggt aaactcgtta ctatatggct cccattttca
     5101 tcttcaaaga ttgtcactcg atatgcagaa gaaattgatt gtgtcttttt tccctctgta
     5161 atctgttgct cgactaaaaa tgaaacgata aattcttccg agtgtttttc aacatctaga
     5221 atttttatag attgaacttc ggaactcgtg ggaatatctg ctcgaaccat atcttggctt
     5281 aaagcgagac cgttttctgt aaggtactgt tcgagattac tcattctctt ttcaattgct
     5341 tccttgttat ttttccatga aaaatattct ttcgcaaaat cctctgtaaa actttcaacg
     5401 cctgaagtat tcactacctt ctcttttata actacttttt catgagtcgt atgctgatca
     5461 atggctgtga aatttctgta gattccaaaa gaaaggctac aagacaataa aagccaaaga
     5521 gcaagcacca tttttcgatg cttgcccact gaaatgactc gttctttatt ctttttttgg
     5581 ttcttttcct tttgattccg ttcaattttt atcttcatta tttttcctct tttctcttat
     5641 ttgtaccgtc cagcaccgat aagatgctgc tgccaatagc tttctgttag atttgtccag
     5701 cccactggat ctcctgcatg aaacatgcga ttctctcctg cataaatacc gacatgggtc
     5761 acataagtac cggcatcata agtcgaatga aagaaaacca aatcacctgg tttggcatct
     5821 tttacatcaa tatgggtcat ggcattatac tgatcttgag ccacccgagg aagtttcaga
     5881 ccaactttgg cataacacca ttgagtcaag ccactacaat caaacccagt ttcgggactt
     5941 gctccaccaa acacataagc cgttccttca tacttaaacg cctcatcaaa aatcccttgg
     6001 actgttttat catcaaactg tgttgtagtt aggtattgct tcactaataa gcaataaaac
     6061 atattgccat agttataccg ccacccacca tttttcttaa tcgctatggg attagggtaa
     6121 tcaacttttt ggccgctcga tttttccttt gaaaaagatt cggctaaagc aaaattatgc
     6181 ttcttcccgt ttttcgtgac atgatccaga tacccgccac catagttata cgcttgaata
     6241 atgctatctt gatcacaccc tagttctttg gaacgcttaa ccaaagacgc aaaatagaga
     6301 catccttgtt tgatggatgc ctcggtactt aatgaattcg gtggcaaccc ggctgactcc
     6361 gaactctgca tcacatcttc cattgtgcca ccagattcca cttgaataat cgccaaaaga
     6421 atcaggacat attctgagat gtttgattcc ttggcatatt tttccaccat tgctcggtgt
     6481 ttcaaaactt cttctgagac attacttccc ccagaagaag cacctgaact attacttcct
     6541 tcactgtctt ccccaaacaa caagcccaca cacatcaaga cgaccataaa ggagagtgtc
     6601 aagatggtta acgaaatgat acttaatttc tttacgttca ttttttctca cccgaccttg
     6661 attttggacg agggttcatt cttttttgta ctttttgatt ggttcgcttg ggcagagtag
     6721 acctctgttt cacttgttgg aaagaatttt tcttacttga tggttgactt attctttttg
     6781 aaacaatttc atgactagtt agttttcgtt tgatttcggg attcggattt actctcacaa
     6841 tctgttttgg tgcttctttt tttggcgttc tatctttttg aggttggcgc tctggtttta
     6901 tcgaaacatt ttcccttctt ttcttatgac gattaccggt ttcgttcaat actttgcgct
     6961 tttcagccat tttttcatct ctatgttgtc gttgtttttc tctcaactcc gctcgatttg
     7021 ctttttcttg gacaagtccg cgcttgaatt ctttcggtgc ttttttcgtc ttttcaattc
     7081 ctttgtggaa gttgtatttc aagttggtcg gcgtattcct tacctgatcc cttacttgtt
     7141 tagtcttatc tttcaccaaa gcttgggtat ccagaacttt gcccattttt ctcccagcca
     7201 aattcattcg ggattgtttc ttattatttg aaactggatt ctccttagtc gactcagatg
     7261 gtacctcgtg atcgttaggt aatcgtgaat tctttcgtag agaagaaccg gatggcttaa
     7321 atttggattt tgattgttcc tttgccaact tatgtccaac tgctgcacca ccgccaaaag
     7381 ccagagttcg gatcacattt cgattgagtt gccgcaattt acggttcatc aacatgtgcg
     7441 gtttccgcat gatgcgcctt cccattgact gactatcatt gctttggaga ttgaacatac
     7501 tcatgatgtc acctaatttg aaatagatac cggcaaaggt cacgatttgc aggaacgcaa
     7561 ccataaagaa aggataggta gccgaaatat tgaaaaacat ggtggagata ctaaaagcag
     7621 tcgtaatgac taaggtaact cccgctcgca tcataatcgt attgaataaa cgaataatcg
     7681 ccttctttcc caagctctca taagttggta acatggataa cagaaaacta attggcagaa
     7741 acatggcgaa aatgataaag agaatttggg agaacaacat aatccccgtc agtaagaaga
     7801 caaagaatga gataccaata ttaaacaaca ccaaaaagac cacggtccct agtcggttca
     7861 tggtctttgt aatacttaga ttcgcgttgt cattgtcttc aatttcagct tttaccgctt
     7921 cttctcgatc ctttccctta tttccatctg gactcacaga taaaatctta ttgacccggt
     7981 cttcaccaat ttcttctatg ttggaatcat caaattgcaa caagagccaa ggttgtcgga
     8041 cttgaatgga aaacaaacta tcacgaatca aatccacact gccttttcct ttgctttccg
     8101 aattcggcac aacgagctct gttccgagac taagagccgc ttcactaaca tccgaactaa
     8161 agttattgat ttttgtgata taggtaggcg catacgcgat aaaggaacca gagagaagga
     8221 agatcgttac aaagttaatg acagcccgga ctgctttggt agcttctcgc tttaatagtc
     8281 cgatatacgc cacatagact cctagagcta aaatcattaa taatagaaat ccaaaataga
     8341 aacccgagac ctgtaatcca ttttcagtaa taccggctag cgtttggata tttttcccaa
     8401 tactttctgc cgtatccgaa ataaaatcca acttgtacgc ttcttgtacc acatatccgg
     8461 tcgcatttga taaatacaaa ctaacggtcc aaatgaaatt tgtaatggcg tagagaccgt
     8521 acatcacact ctttcctaaa ccatctcccc agttccaagg cagccagccc cacgaactat
     8581 ctacaaagaa atccaattga tagttatcaa gcgaatattg agaatagaga ttgccagatt
     8641 taacggtatc atcaactaat ccagttgctt ccgctaatgt tccaatcaga ctcaaaagaa
     8701 gtaaaatggt gcagagacta attgcaatta ttcccacaat ccgtaaaagt ttctttttca
     8761 tctcctcact ccattctctt ttgaacaggc gggcgtgtat caaaagcatg gaagagttct
     8821 tcaaagactg gatgcacttg taccacacca acgcgaccat acaagtcctg catcaaacat
     8881 tgctcatttt ccaaatctcg cagacgcttt tgattgcttt catcttcttg atcaagacca
     8941 aagaattcga gtgtcttctt gatttcatga atatctgtgc ttcgaaaggc aaattttagc
     9001 ccaatgttgt ttttcagacg ttcattcaat aaatcatcac tattttgagt gacaaagtaa
     9061 acgccggcat tcatagcacg gccagcacga actagtttat tcgaaagagt ttttccttgt
     9121 gcgacttgaa gaaagctcca agcttcatcc aaatccacaa ttttaaagat ttctcgattg
     9181 ctatgaataa aatctagggc aaatgtagag ataacaatca acatagaaac actaagcaat
     9241 tccatcgtag tgtactcttc aaacgtagtc tccgcatctg gtaaaaccaa atctgccacc
     9301 tgaatgatat tcaattgttt atccaaacta atcgattgtg taattgaacc atccgaaaaa
     9361 agtaaatgcg caaaatcata atcggtaaac gattcaatat gatcggcaat attttccgca
     9421 actggcgagc cctcttttcg aagctcatta atgacttgta gcaatcctcg ttgctcactt
     9481 tgggtaacgg ttcgaatagc cttgcgtaaa acgggaaact tctccccatc tcgacttgaa
     9541 attcctgtta aaaaggtcag aatatcaatc gctagacttt ctgagtcttt ctttttcttc
     9601 ataatcacat aaggatcaag cagaccttgg ttttctggtt tactagttaa gttgagaata
     9661 ttgatttcat ccgtaatttc tggcaaggtt tctttccagc cacctcgttc tcctttggga
     9721 tcaacaatta ctgcttgacc gccaaataag acagcataat aaactaggag attattgcta
     9781 aaggatttcc caccaccaag tgaaccaaga aaagcagcag ccaatgcatt agtgatagaa
     9841 cctttgactc cttgtgaagc caatgccggt ttcagataaa cgttacgccc tgtatccaca
     9901 ttgtagccaa agtaaatgcc ttccaactct cctaacatct gtgtagctcc aaaaccaagc
     9961 ccagcaagaa aatcagacgt aacatactga atatagtcgt tcatatatcg tttacttgag
    10021 ggtaagaatt cttcatgtag ccccatcatg tcgccaaaag gacggactaa ttttacattg
    10081 gtatcatcat aaaaatcgaa cacttcatca caccggcgtt ttaattcatc caatgattct
    10141 gcactcactc gaacgacata gcttaatttg tacatggatt ctttggattg atccaacatt
    10201 gtttctagtt catccacgga gtccagagca tccaggacat tggaattggt ttcattgtcg
    10261 gactggtatg catgattgtc taagtctttc agttcttttt tcttattacg aactgtcgcc
    10321 agtgcctttt tattcgtcac gatttctaca ttcatactag tgtcgattgg gaaagtgaat
    10381 tgttgttgct ggtaataaaa gagttccgaa gaaggaaact ccatctcacc gacaatcgta
    10441 ttaattgtta gataggccac ataagattca tgattctcat gctccattcg taaatatcgt
    10501 ggcttctctt caatcaaaca gcgacttgga cgaagtaggt catagcgctt tatcaatgtt
    10561 tcagatttta gctttctctt cggtagttga aattcatatt cctcaaatgg tgttcccttt
    10621 tctccataaa tatgttcaat caaataagtt agatcactag gtgttactcg tcttactttg
    10681 aatctacgag ccaatttact ttccatcaat ttttcaagct tagtataccg gcgaatttct
    10741 tcattggata aagaaacaaa atcacccatc aaatgatgat tgaccccata aacaaactct
    10801 tgaagtccgg ataaaaaaga gttttttaga cttttcaagt tcacttcttc gtctgtgaca
    10861 atcagtttga agccaataaa aaagcgatag tcaatttgac tatcgccaat catcgatact
    10921 aaagcatctg tctgtaagtc gattctctgt tctgcgactt ctttcaaacg accagttatc
    10981 tcttttttcg accgttcctg cgtggcacga atgctgcttt ctgtcgcaat ttgtaaagca
    11041 tggatcctcc cttctctatt ctgagcaatc aattgacgga aattatcatg aacttgatac
    11101 ttttgctcag gagataagaa ggagtaatta tagggtacta actcatagta ggcaaaacac
    11161 tcgctatctt gattaaagac gaggttattt tcgatatact taatcgggta catcattcac
    11221 actcctcact aaggtaattg cttcattcca tcgtttcttc tgttctttga ctttctttcc
    11281 tgcaaaggta accttaaatc gcaagtgata actaataaag gatcgtaaaa accctaatgg
    11341 cttctttcca tcaaaggtct tttgcgacat aaaccaagcg actgccacag gtatgcccaa
    11401 gtattttaaa aatgccccct ctatcataga tagtggaggt acatgagcaa acacaatgac
    11461 aaacagcaag gataagacaa accaagccat ttgattaaag gttacaggaa aaggcagctg
    11521 aaagtcattg attgcgtaaa tgactttttc aactgcccag atactggtat agctttttat
    11581 ttttttcatt agtttcactt cctaaaaaag cgcctgataa agacgactct gcatgaatat
    11641 taattttctt tttaaaagtg tattccaact ttcaatctat caactgaggt ttatcagacc
    11701 ataatctgtg aatttcttgg tatccagctg aagtaataaa agtatatctt tgttgatata
    11761 ttctatcttg aaaatcacta aaccgtattt ttatttccca tttactcact gaatctttag
    11821 ggatactcat tacttcgtta ttatatttca tccaatataa ttcaaattct gttttttccc
    11881 tactcttaga atatctgtat caataggcgc tgaaactcct aacgcatcca gactatcatc
    11941 aatatgtttt tgagccgaaa gtaatgataa tagatttact tcatggtcgt ttgtgtcgat
    12001 agtttcttct aaatacacaa agtcaattga aaaagccatt cccagacctt cattaataag
    12061 ctcaaatggt aatttaaaaa catcattttc gtcagacttt accattttac cagcaaaacg
    12121 gtgttcagat attttgggta taagttttaa ataagggtaa taacttagac ggtcttgctc
    12181 ttcatttctt tgtttttcat cagcatattg ttgctttgat aaatcaagtg attcctcatg
    12241 ttgtctctct tgctgtttca tcgctttttt atgttgttta tttgtaaaaa aaagtgtgat
    12301 aaaacatact gcaaatgaag ttagtacagg gacaaatatg tctataaatg atttaaggtc
    12361 aaagtcaaaa ttcataataa tcataacctc cagcattata tatttatcaa taattatatc
    12421 cctaaaccta tatcatgaaa atgtttatcc tatgaattca aatgttcctc tatttgtcac
    12481 aagataattt ccttctagtt ccaagtcacg tccatatgct tcatagtcaa tatagttttg
    12541 caagtgtgta ggcacctctc ccaaagcacc tgtttcttca atcaaataat acgccacatc
    12601 actcatatcg ttacaatcgg gataacagat aatatcatcc acatgctcca ccatttcctc
    12661 aaaagagttg aagaaagcat gttggatttc caaagcaact tcaccaatcg gtgttccttc
    12721 tagttcctct gctaaaccac acaaccgatt gatttcctca attggtgtat attcatcaat
    12781 ctcaaaaggc aactcataat catggatcgc atactcttcg tattcgtcat ttaaaccaat
    12841 ccgttctttc acttcgtcaa aatcgacagg tgggctaaac caagccccca ccaattcacc
    12901 ttcgttatat tttccaaggt tcgcaatata tacacgcatc tgctccataa tggtccccct
    12961 tacgcaccga caatccgatt aaacaagttg agtaagacat ctttcacacc agaagcgttg
    13021 aagaccagtc ctaccgcaat cagcgcaatc accaaaaaac caatcagctt ggaaaactca
    13081 cgtttgaagc ctaaaaataa accaatgacc acaattgcca ataagactaa agattgggca
    13141 ttggttaaaa accatt
//
LOCUS       DAPBBR010000067        13084 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPBBR010000067 DAPBBR010000000
VERSION     DAPBBR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.070"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(79..2199)
                     /locus_tag="RD488_002274"
     CDS             complement(79..2199)
                     /locus_tag="RD488_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7658331.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="RD488_002275"
     CDS             2429..3607
                     /locus_tag="RD488_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDT7658332.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="RD488_002276"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="RD488_002276"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDT7658333.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="RD488_002277"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="RD488_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDT7658334.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="RD488_002278"
     CDS             complement(4960..6213)
                     /locus_tag="RD488_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7658335.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="RD488_002279"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="RD488_002279"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDT7658336.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="RD488_002280"
     CDS             7790..9136
                     /locus_tag="RD488_002280"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDT7658337.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="RD488_002281"
     CDS             complement(9444..9830)
                     /locus_tag="RD488_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7658338.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10098..10247)
                     /locus_tag="RD488_002282"
     CDS             complement(10098..10247)
                     /locus_tag="RD488_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658339.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10709..10921
                     /locus_tag="RD488_002283"
     CDS             10709..10921
                     /locus_tag="RD488_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658340.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="RD488_002284"
     CDS             complement(11199..12998)
                     /locus_tag="RD488_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7658341.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4290 a         2353 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 ttta
//
LOCUS       DAPBBR010000068        12410 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPBBR010000068 DAPBBR010000000
VERSION     DAPBBR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.071"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="RD488_002285"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="RD488_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDT7658342.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="RD488_002286"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="RD488_002286"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDT7658343.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAVDFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="RD488_002287"
     CDS             complement(2169..2906)
                     /locus_tag="RD488_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7658344.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="RD488_002288"
     CDS             complement(2997..3524)
                     /locus_tag="RD488_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658345.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="RD488_002289"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="RD488_002289"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDT7658346.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="RD488_002290"
     CDS             complement(4401..4886)
                     /locus_tag="RD488_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDT7658347.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="RD488_002291"
     CDS             complement(5039..5236)
                     /locus_tag="RD488_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658348.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="RD488_002292"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="RD488_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HDT7658349.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="RD488_002293"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="RD488_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HDT7658350.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="RD488_002294"
     CDS             9211..9423
                     /locus_tag="RD488_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDT7658351.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="RD488_002295"
     CDS             9425..11104
                     /locus_tag="RD488_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7658352.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="RD488_002296"
     CDS             complement(11358..11558)
                     /locus_tag="RD488_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7658353.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11869)
                     /locus_tag="RD488_002297"
                     /pseudo
     CDS             complement(11708..11869)
                     /locus_tag="RD488_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(12249..12322)
                     /locus_tag="RD488_002298"
     tRNA            complement(12249..12322)
                     /locus_tag="RD488_002298"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12286..12288),aa:Ile,seq:cat)
BASE COUNT         3623 a         2672 c         2155 g         3960 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcaacggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa taacattacc agaaggataa tataggttag
    11881 tacacgtata aaaatatctt ttatattgac acaatttatt taacaagtat aataataatt
    11941 gaaagtgaat ttaaacaaat atacaccata aacacaacgt acctgcgaat acgttgtgtt
    12001 tttttctttt tcaaaaaaag acgcttaccg ctgcgaaaca gtaagcgcca ttgtcggctc
    12061 taatgtttat ctagccaatg actaaataat gccaaagtta aaccaattaa caatggcaag
    12121 agcacgtgct ccaaagtgaa ttcaaacaaa tcatacacct cctcccacga aaatctctgt
    12181 ggaagcgacg agccgacatt ttattatacc attattgaat tttatttttt atcaaataga
    12241 ttaaattatg taccctgtag gactcgaacc tacgaccgga cggttatgag ccgtctgctc
    12301 tgaccaacta agctaagggt actggttgtt gccacataaa gccataaaca atcaaccagt
    12361 agaaggtgtg gcaacaatcc tgttatcgca taattttgga gtgtgattag
//
LOCUS       DAPBBR010000069        12269 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPBBR010000069 DAPBBR010000000
VERSION     DAPBBR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.072"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..572)
                     /locus_tag="RD488_002299"
     CDS             complement(<1..572)
                     /locus_tag="RD488_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7658354.1"
                     /translation="MDQAKSLETACKLLRLSHVLPTLVRKDLDYSFETKEDWLMYLLE
                     KELACREELKTARLLKQAKFPNKRTLEDYEWHDHICLPNATTKDELLSLSFIHQKENA
                     VFVGTPGTGKTHLACGLGQLAAKSGIDTRFWRVSDLVNELEHHWKNNTLEVFKHRFDK
                     VKLIILDEMGYVPFTKEGAELLFQLISDWY"
     gene            complement(572..1996)
                     /gene="istA"
                     /locus_tag="RD488_002300"
     CDS             complement(572..1996)
                     /gene="istA"
                     /locus_tag="RD488_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDT7658355.1"
                     /translation="MLTMTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLL
                     PQPKARKKTGMMYTEKWGGIVSLWLSEDAKLPKKKRRTAEAMTTALKADGFPGSYRTV
                     CVFIQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPF
                     SNAGFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVTQTKTKTEQAVLTD
                     GFLRFSMHYGFETQVCNPRSGNEKGSMENKVGYVRYNFFSSTPIMKDFASFNEALAVE
                     LSHDRERIHYEKHVIINDLWNTEKTDLLALPDTDYPVFKEIEVKVNKYNEIKLDNERI
                     HVPRVRNYSIIYGLLRFDSYQLISTDGEIISEGLRPYMMKKRAIDWQAILPDWRRKSR
                     AMHYSRYWKYLPERIKLFLSHPDWKEQEKRLNQISGLLVTHDMLGIDTHFYDMFSAST
                     TTDAYDIDWHQYDAFLSLTGEVID"
     gene            complement(2391..3233)
                     /locus_tag="RD488_002301"
     CDS             complement(2391..3233)
                     /locus_tag="RD488_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7658356.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            3558..3974
                     /locus_tag="RD488_002302"
     CDS             3558..3974
                     /locus_tag="RD488_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7658357.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIRESQQSVIDCRKLLVEQLTGGDDL"
     gene            3971..4441
                     /locus_tag="RD488_002303"
     CDS             3971..4441
                     /locus_tag="RD488_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7658358.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            4455..5228
                     /locus_tag="RD488_002304"
     CDS             4455..5228
                     /locus_tag="RD488_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658359.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            5242..6054
                     /locus_tag="RD488_002305"
     CDS             5242..6054
                     /locus_tag="RD488_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7658360.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            6108..7073
                     /locus_tag="RD488_002306"
     CDS             6108..7073
                     /locus_tag="RD488_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7658361.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            7210..9933
                     /locus_tag="RD488_002307"
     CDS             7210..9933
                     /locus_tag="RD488_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7658362.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9946..10578
                     /locus_tag="RD488_002308"
     CDS             9946..10578
                     /locus_tag="RD488_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7658363.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            11477..>12269
                     /locus_tag="RD488_002309"
     CDS             11477..>12269
                     /locus_tag="RD488_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7658364.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3977 a         2026 c         2378 g         3888 t
ORIGIN      
        1 tcataccaat cgctgatcaa ttggaaaagc agttccgcgc cttctttagt gaaaggcaca
       61 taacccatct catcaagaat gattaatttt actttatcga agcgatgctt gaagacctct
      121 aaggtattgt ttttccaatg gtgttccaat tcgttgacta aatctgatac ccgccaaaag
      181 cgtgtatcga tacctgattt ggctgccagc tgacccaatc cacaagctag atgtgtttta
      241 ccggtaccgg gtgtacccac aaatacagca ttttctttct gatgaataaa cgatagactc
      301 aataattcat ctttagtcgt cgcatttggc aaacatatat gatcatgcca ttcgtaatcc
      361 tctaaggtac gtttatttgg gaactttgct tgttttagga gtcgggcagt tttcaattct
      421 tcacggcaag ccaactcctt ttccagaaga tacatcaacc aatcttcttt ggtttcaaag
      481 ctgtaatcta agtctttgcg aaccaaagtg ggaagaacat gggaaagtct cagcaactta
      541 caggcagttt ctaaactttt tgcttgatcc actagtcaat gacctcccct gttagagaca
      601 agaaagcatc gtattggtgc caatcaatat catacgcatc ggtagtagtc gaggcactaa
      661 acatgtcgta aaaatgtgta tcaatcccta acatatcatg tgtcaccaat aaacctgaga
      721 tttgatttaa acgcttctcc tgttctttcc aatctggatg actgagaaat aacttgattc
      781 gttcgggcaa atacttccaa tagcgagagt aatgcatggc acgcgatttt ctgcgccaat
      841 caggaagaat tgcttgccaa tcgattgctc gttttttcat catataagga cgaagtcctt
      901 ctgaaataat ctcaccatca gtgctgatta gctgatagga atcaaaacga agcagcccat
      961 aaataattga ataattgcgt acacgtggaa cgtggatccg ttcgttatct aatttaattt
     1021 cgttgtactt attgactttg acttcgattt ctttaaatac tgggtaatcg gtgtccggca
     1081 aagctagcaa atctgttttt tctgtgttcc atagatcatt gataatgaca tgtttttcgt
     1141 aatggattcg ctctcgatcg tgtgacagct ccaccgctaa tgcctcgttg aaactggcga
     1201 aatccttcat aatcggtgta gatgaaaaga agttgtaccg tacatagccg actttgtttt
     1261 ccatactacc tttctcgttt ccgctacgtg gattgcacac ctgtgtctca aaaccatagt
     1321 gcatagaaaa tcggaggaaa ccgtcagtca gcaccgcttg ttcagtcttt gtttttgtct
     1381 gagtaacggc cgttgacata ttatcaatcc gtattttccg aggaacgcca cctgattggc
     1441 tgaagagttc tttcatgcct tccaacaaac attcttgatt ctcggcgggg agtacaacgg
     1501 cgaatcctgc attactaaaa gggaaagtca tcactaatac cttcacatct ttaaacgctc
     1561 catcgtgaca aacttccatc gtaccaaaat caagttgcgc ttctgctggc gggtgttcaa
     1621 gacgttcaaa gccttggtct tccagtgttt ccaagtagtg tgtcgctttc caatcttgaa
     1681 tgaatacaca gactgttcgg taggatcctg gaaagccatc ggcttttaaa gcagtagtca
     1741 ttgcttcagc agtcctacgc tttttctttg gcagcttagc atcttctgaa agccataggg
     1801 aaacgatgcc tccccacttt tctgtataca tcataccagt ctttttgcgt gctttaggtt
     1861 gcggcagcaa atcatcatct gcatattttt tagccgtgcg ccaatttaca tctagctcct
     1921 ttgcaatatg attaatggat ttatcatgat tatttcgtaa atttctgata gtattaatat
     1981 cggtcattgt gagcatacct ttcttacctc cagttacagt gtcgagacta taactttaga
     2041 ggaatttcag gttgcccgca atggcttttt atcttaactt aatcgatttg cggagttgtg
     2101 tagtttttcg ttgcacttgt atgtactttt attctgccat aaacagctta atgaatgtcc
     2161 acttgaaaaa gtgaataaac gaaatagatg actcgattta ataaggaagt aaacccacac
     2221 agaaatatag gtgattttcc ttgaatgacc aagatattga aagttagtga aaaaacacaa
     2281 aaaggtagcc ctattcacag aaggtctgcc ttttgtgtta tcgccagcaa acattagagg
     2341 ggatatttca tatagctttt gtcctctcga cagtcctatc agtttctctt ttaacttatc
     2401 tctaagtgct gtccagtttt aatagcttct agcttgtttc ctaactgtgt ttttaatatg
     2461 ttgaaggctt ttgaacctgt gcagtggcaa gtaaggattt tttctactcg tgagtcattc
     2521 aatttatttc caattttcat tacctcttgc tcaggtagac ctaaattatt tatataaggt
     2581 atgccaatca tatggaagcc accgattagg tattttatgg gtttagtcgg aaatgtttca
     2641 agagcaattt ccatcatatc gataatgcca tgatgactac agccagtaaa gacaatcaga
     2701 ccgtcttctt gctcaattac gaccaataat tcatctgaaa aatcatcata aacaaattta
     2761 tcatccatct ttttgtataa attcttggtg gtcgagtttg ctttgcctag ggggatgata
     2821 tggaagctcg gagcaagttc tgttttcgtt tttattgtat gtaaattctc atgcatttta
     2881 aggatttcat ttttaggaat accaacatac agaaacgtgg ttaaaatctt taaataatgg
     2941 ggtaaagtta caccttcagc tgtataaata ggggcgtttc ctgattttaa atatcttaac
     3001 ccgccggtgt ggtcagaatg accgtgtgaa ataatcactg cctccagatc attcaaagtt
     3061 tcccccattt tagtcgcatt atagactaat tttttattag cgccagcatc gaagagatat
     3121 ttcttccctg agtagttaat taagagagat aacccatgtc cacttttaaa gttcaaattt
     3181 attcttgagt tttcaaataa aaccttgatt tccactataa catctccttt cacatgaacg
     3241 tgtattcata tattgtagca cattaagttc tattttttgt tgtaattacc gaaaaaaata
     3301 ttaatggacg ctttttacgc tttatttcgt atgtggaaga aaatttctta ggatgtggcg
     3361 ggggattggg gcaaagctaa attccaatta cagtgatcat ttaattagac acctttaaat
     3421 acccacactt tcatcaacac tataatttag ggaaagaaaa gtgttggcat gatatagaaa
     3481 aacctttaat tgacagcgtt tcctaaaatt ggcacgcatc ttgcttatag aaaagcgtaa
     3541 ggataggagg aatgaaaatg gcaactataa ttcttgccag ccatggggaa tttgctcaag
     3601 gattaaagca aacagcgaca atgattattg gagatagtgt accaattcat gccttgtcag
     3661 catttagaga tgaagatgaa tctattttgg tacaaataaa aaaactttta gccacaatag
     3721 atatagaaga aacctacatt ttaactgata ttctaggtgg tagtgtgaat aatgatatgc
     3781 tcactattat taaagagtat gagggattgc aattaattac tggaatgaac ttacctttag
     3841 ttatttctat tgcaacctat aatggaaaaa ttggggaaag tgagctagaa aagcttatta
     3901 gagagagtca acaatcagtg attgattgta gaaaattatt agtagaacaa cttactggag
     3961 gagatgacct atgattaaat tagtacgtat tgaccatcgt ttgttgcacg gacaggtagt
     4021 attttcttgg agtaaatcat taaatatcaa tcgtattatt attgccaata aagaggcagc
     4081 gaatgatgaa ttcaaaaaaa tgtctttgaa tttatctaaa ccgactggca ttaaattaac
     4141 aattttttca gttgaacagt tactagaaaa aatgcctaaa atcgaaacac ttaacgaaaa
     4201 tatcatgctt atttttggta atacaaaaga aattcgtcaa ttttgtgaag cctatcctaa
     4261 agtacaagaa atcaactatg gagggataat caaaaaagaa ggttccaagc aatttagtaa
     4321 tgccattttc ttgaatgaat ctgagcaaga agatgccaaa aaattaaaag ctcttggcat
     4381 taaacaattt attcaacagg taccaacttc taaaaaagaa gatttgaata caatgttata
     4441 aaggaggaat gaaaatgctc gttcagtcaa ttggtttagg gttaatcggt gttttttgta
     4501 ttttagactc aaggctttta ggaagaatga attttgaacg accgttgatt gtcagtacgc
     4561 ttgttggttt ggtacttgga gacatggaaa aaggattaat tgttggagcc tctttggaat
     4621 tgatgtcctt aggattagta aatatcggag ctgctgcacc acctgatatg aatatggcat
     4681 caattattgc tacagccttt gccattttat caaatgcgaa cgcagaagca gcattaacga
     4741 ttgccattcc aatttcagtg ttaggtcaaa tactaggtat cttaatgcgg acgattttgt
     4801 caaatttgac tcacgttgcg gatcgcttta tcgaacaagg gaaatttagc caagcaagga
     4861 gaattcatat actttatggc tcgggattat atgctctcat gtattttatt cctatttttc
     4921 tagcaattta ttttggaacg aatcttgttt ctcagattgt tgatgcgatt cctgagtggc
     4981 taacaaatgg cttaacggtt gcaagtaaaa ttttaccagc atatgggttt gcgttgttat
     5041 tacaaacgat gttaacgaaa aaaatggtgc catttttatt acttggattt ttaattactg
     5101 cttattctgg attgggaatc attggtattg cagccttcgc atgtattgtt gcgtttgtca
     5161 tggttcaagt tcaaggtaaa aactcaaatg gtaaccaaaa tgagccagat ccattagatg
     5221 acttataagg aggtagatta agtgaaagag aaagatcaaa atgcatggaa atatcggcag
     5281 ttcttatggc gttcatgggc aattcaagcc tcatggaact atgaacgaca aatgaacatg
     5341 ggttttatgt acggaattgc accaattcta gataacattt acaagaatcc agaagatgaa
     5401 gcaatgaaga aagaagctta cgagcggcat atgatgtact acaactgtac ccctcaaaca
     5461 agtgcatttg tgttagggtt aactgcttct atggaggagc aatactacga agaccaagaa
     5521 aactttaatc cggaatcaat cagtgcagtg aagacttctc tgatgggacc gctatctggt
     5581 gttggtgatt ctttctttca aggaacgatt cgggtattag cctttggact aggaattaat
     5641 ttagcccaac aaggtagtat tttaggtcca attctagcaa tgttaatttc ctttgtacct
     5701 tcctttttag ttacttacta tggtgggaaa attggctata acatggggaa taaatacttg
     5761 tctaaactgt atcaagaagg tttgatggat aaagtaatgt atgtttgctc cattgtgggg
     5821 ttgatggtca ttggttcgat gattgccagc atgatcggga ttacaacacc aattcaaatg
     5881 ggtaaagctt ttgtcttaca agatgtatta gatagtatta tgccacaatt tttaccatta
     5941 ggattaacct tcttcatgta ctggttattg cagaaaaagg tcaaaacagg atggatgttg
     6001 gcaatctgtt tagtcggagg aattattttt agtttgttag gtatcttaca ataagggaat
     6061 aaccaataaa tttggttgaa taatataaat aaggaggaat tcaattgatg aattcaaaag
     6121 aaattgttaa agaaatcgta gcgaaaaaag aggtaaaatc aatcgtattt gttggctgtg
     6181 gcgcttcaaa agcggacctt tatcctgcaa agtattttct agaccaaaat gcgaagcagt
     6241 tacggattag tcattacaca gccagcgaat ttaactatgc aacaccagca tctgtagatg
     6301 agtcaactgt cgttatttca gcttctttag gaggtacgac tccagaaaca gttgaagcta
     6361 acgcagtagc taaagaaaaa ggtgctacag ttattagtct aacacgaagc attgactcac
     6421 cgttaacaaa agatgcagat tatgtaattt atcatcgatt tgcagagaac tatgctgcta
     6481 aattagaaaa aacaggctac tgtttagaat tggcagtaga acttttacat caagtagaag
     6541 gttatgacca ttatgaagca atgcaagaag gatttgctac tatctatgat cttgcccaaa
     6601 aaagtgcaga atcagctcgt aaagatgcga agaaatttgc tgaacgcttt aaagatgaaa
     6661 aagttattta tgtaatgagt agtggtgcta cacatgaagt agcatactca acatcaattt
     6721 gcttgatgat ggaaatgcaa tggattaatt ctggtacctt ccattcagga gaatttttcc
     6781 acggaccatt cgaaattgtg gataaagacg taccgtttat attattaatg aatgatggaa
     6841 aaactagaaa tatagatgct cgagcattaa ctttccttga acgctttgat acgaaaacag
     6901 aagttgtaga tgccttggat tatggcttgt cttcacatat tgctaaagaa gtcttagact
     6961 actttaaccc attcgtgatt actgcagtat ttagagttta tgcagaagaa ttgtcagaag
     7021 caagagaaca tccattaact aagagacgtt atatgtggaa actaacttat taaaaaatag
     7081 atcaaactaa ataaggtggc ttgagaaatt aagccacctt gttttcttca atgtgatttt
     7141 atacatatgg taaaataact agtacatatg gtaaaataac tagtacatat tgtgaaagca
     7201 ggtggcaaga tgcagcgatt aaatgactat ctttatcaac taacattgct tttgaaatct
     7261 acgccttcag ataattattc agctcgcagt atttcgcaag ctttacagtt gaatagaagt
     7321 acaatcagta gctacttaaa tgaaggtgtt cgtgaagggc ttttcataaa agtaaaaagt
     7381 tacccggttt tatttttaca tagaacagct cttgaagaac tacatatcac actgaataac
     7441 tccgaaatag aatcaattga aagcttgtta acaatttctc aaaaacccgc attagatcaa
     7501 gtaattggct ctaaaggaag tttgaaagaa gcaattgatc aaattaaaac ggcagtctta
     7561 tatcctggaa aagggttgcc tttattattg atcggcgcta gtggatcagg gaaaaccttt
     7621 ctagcgaata aaatatatga atatgcagta gaagaaaagg tcattcacac atcggcacct
     7681 ttcatagatt ataattgtgc acaatatgtg agcaatccag agttactatc ctctgcttta
     7741 tttggctaca cgaaaggagc atttaccgga gcaagccagg agcatactgg tttgctagaa
     7801 aaagccgatg gaggagtatt gtttttagat gaagtgcatc gcttatctga agaagggcaa
     7861 gagaaattat ttacatttat ggatacgggc gaattctctc ctatggggga taatagtatt
     7921 cggaaaaaag ccgatgttcg attagtcttt gcaacaacag aaaatatata tacgactttc
     7981 ttaccaactt ttcttaggag attgccagtt attgttaatc tacctagatt tcaacaacgt
     8041 ccgtcgtttg aacgtctgtc attgattgat gaattttttg tttctgagag taaaatttta
     8101 gctaaggaac tatctgtttc tgatgcattg attcatttct taatgaatag tgattttgaa
     8161 ggtaacgtgg ggaatattaa aaatattatc aagtatgctt gcggaaacgc atatatccac
     8221 cagaagagtc agcaaacaat tcaagttaaa ttattggata tgcctttaga gtacagttat
     8281 aaattcaagg agcaactaaa taaacccaga aagaaaagag cagatcgaat ctactatcca
     8341 gaagaaacac gacaagtgca actagaaaga aacaatcagc tttttgttca attttttgac
     8401 caattactta ctggattctc tgaagtgatt gaaaataaca aggatattaa actattttta
     8461 gaagaaatgg ttaccaaggt aacacaagta atggatacgc ttatttttca agaggattac
     8521 gaaaaagagc agtctttata cgccattcta aactatcata ttcgtcaaag tattgatttt
     8581 atgcgagaaa gctacgggtt tgaacaagat ggtaaccggg tagtcgcttt ggccaactat
     8641 ctatatgtca aggataatca agtgattttt gaaaatagtc ttcaagaaaa gaaaaccaaa
     8701 gatcagctta acgaattttt tgctaatgtt cttgaaaccc cttattggta tgcaaaaaaa
     8761 atcttaagcc ttttatctga gtgtttagat caacctgtgt atgaagagga cattttcttt
     8821 attacgctat atttttatag tttgaatgtc acgaatgtta aaacaggtat taagagtatt
     8881 gtgctagctc atggttattc tacagctagt agtatggcga atgttgccaa ccgtatgctg
     8941 aataagaacg tttttcaagc ttatgatatg cctttagata ttacattaga gaaaattgaa
     9001 gcaaaattga ttcaattcct tggagattat cgaacagatt caggcttgat tttattggta
     9061 gatatgggtt cactaaacca actaggcggt ttattagtga atcatctaaa tggaccactg
     9121 ttaatcattg atcatatcaa tacaccgtta ttattggaag tcggccaaca agtattaaac
     9181 aataaaagta tcaccgaaat aggagcagaa attgaaacaa gtcttacttt caaaaagcag
     9241 ttactacttc ccaagaaaaa gaaaaagaaa gccatcatta cttgttgtta tacagggatt
     9301 ggtagtgcga cccagattca ggagatttta acgaaatgct tgaaagatgc agttagagaa
     9361 ttagtaatta ttccgtatga ttacaaaaag ctgttagaaa acaagaattt tgagactcct
     9421 tttcaattat acgatgtcat catgattgta ggtacagaag atcccaaaat taatcagatt
     9481 ccatatattg gattagatcg cctgattaat ggggaagcaa ttggcgaatt tgttcattac
     9541 ttggaaaaag agctgactat tgaagtgaac gatttacaaa aagaattaat tttcaatttt
     9601 tcaattagta aaattgtcga aaatttaacc attttggatc cagataaggt gctatctttt
     9661 gtacaaaaag caattaaaga attatcgaag ttattaaatt ttgatttttc taataatcag
     9721 ctgtttttgt tgtaccttca ctgtagttgt atgattgaac gaattgtacg taaagaaagt
     9781 gtggatgagc aagaggacat tgaagaatat atgcaagcaa atggagaaat aatggataaa
     9841 attcatagcg ctttttttga gattgaaagg gaatacacaa ttgaaatacc agatttagag
     9901 ttgcgattat tgagcgatat tgttcaagga taggagtgaa ttcgaatgac aatgggagta
     9961 atttttgata tggatggggt actcatagac agcgagacat tttattttga gagaagaatg
    10021 aacttctttc aagaactgga gatagatcca ggatcaaacc agattgatga ttatgtgggg
    10081 aaaacagaag ctgcaatatg ggaaacatta gttcctgagg acaaatcatt aagagaggaa
    10141 ctttatccga aatatgtaga ttatcgaaaa acgcatccaa ttgatttcgc taaagattta
    10201 cgaaaagaag tgaaaccgtt acttgacttc ctcaagaagc gggatatacc attggcactg
    10261 gcatcttctt ctccagttgt tgagatagag agtatgctca ttcaatgtga acttactgaa
    10321 tatttttcct ttgttataag tggtgagtca ttaaaacaaa gcaaaccaca tcccgaaata
    10381 tatttaaaag cgaaacagca attagactgt gacttcttta ttgcagtaga ggattcaacg
    10441 attggtatta aatcagcaaa ggcagcaaat atctatacgg tggcactaaa acaaccaatg
    10501 caaatcgatc agagtgaagc agacatacaa attgaaagtc tacaagaact ggaacaaatt
    10561 gttttagaaa aaggttagtg aattaatgga aataaggcta tatatctgtg ctagctattt
    10621 tgactaacca aaaaaacttg ctataattca ggtgtagtaa aaggtgctgg taacaccttt
    10681 tacgaaaatg cttcggcagt gataatggga ttggcttttt aagtttttta ttttgctcgc
    10741 aatccctaag gtcatgtgaa tgatcctagg gattgctaga atattttgca acattctatc
    10801 tatttcagaa cgtaaccttc cccagttcat tgggattcat tagcatacaa ccaacatttc
    10861 aaaaagaaat tgcactacac cattattagc tattttgact aaccccaaaa aacttgctat
    10921 aattcaggtg taggtaaaag gtgctggtat caccttttac gaaaatgctt cggcagtggt
    10981 aatgagtgtg gcttaaagga ctagtccttt aagcttttta ctttgttcgc aatctctaag
    11041 atcaagttaa tgatcgataa gattgctaga atattttgca acattctatt tcagaacgta
    11101 acctttccca ttccactgtg attcattggc aaccctcctc acaaccaacg tttcaaaaga
    11161 aattgtaaag ttgttggggt accacgaccg aacaatacta cacctgaatg atagtaagtt
    11221 gtctcattaa gtatagcata tcctcttttt gggtaaatag aaatcggtta cattttttat
    11281 ccaagaccaa gttttttcat ttggtcttat ttgctatacc caaacaattc cgcagtatag
    11341 tcgacggtat tgattttatc aggtgagtaa tagaaacttg ttttccttcc ccaaaacatt
    11401 acctataaag gagaaaaaat ggtatcgtaa ttatataggt ataggatgaa atttttttct
    11461 aagaggaggg ttgttgatga aaaatttaca gttaaaattt attgttgatc catcgattgt
    11521 acgctggttt cggattatca atcaatttga gcgcaatcaa cttgccacaa aaggagaatt
    11581 agcaaagagt aatcatgtat ctgaacgaac cattcaaaca gatgtcaata aaatgaagga
    11641 ctacttttct gaaagtgttc aatttgtttc aacgaaaagt gggtattctt ttcagaagga
    11701 aagaccggtt ctttttctca agcagaagga gcaactactg gagaacgaaa ttttatttga
    11761 gttgttaggg aatgtctttt atggcgaatt ggaagatatg acggagctaa ttgatcgttt
    11821 tcatttatct gaagcgactt ttcgtcggta tttgaagcag attcaaccag ttttggaaga
    11881 atacggctta gaattgagtc tttatcctct tgatttaaaa ggagaagagg caaatattcg
    11941 caagtttttt aaagacttct attatgaggg ggagatgacg ccccatactc ttgttccacc
    12001 aagggatctt catgaacttg tgcaagctac attctatgat aaatttgagt atttctcgat
    12061 tggaacaggg acttctcctg ctgaatttta ttatagtttg tatattgcga ttgagcgtgt
    12121 gagacaagga aaaacgatag ccattcctca aggtctgatt gagcgagtaa ttgctagtga
    12181 gaattttcgc ttaatgtatt ccttgaaaga agcgattcaa acaaattatc aagttgcttt
    12241 atcagaagag gagttttgtt ggttgtatt
//
LOCUS       DAPBBR010000070        12187 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPBBR010000070 DAPBBR010000000
VERSION     DAPBBR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.073"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(368..1486)
                     /locus_tag="RD488_002310"
     CDS             complement(368..1486)
                     /locus_tag="RD488_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658365.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1957..3264
                     /locus_tag="RD488_002311"
     CDS             1957..3264
                     /locus_tag="RD488_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDT7658366.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3383..4582
                     /locus_tag="RD488_002312"
     CDS             3383..4582
                     /locus_tag="RD488_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7658367.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4609..5877)
                     /locus_tag="RD488_002313"
     CDS             complement(4609..5877)
                     /locus_tag="RD488_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HDT7658368.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(6040..6686)
                     /locus_tag="RD488_002314"
                     /pseudo
     CDS             complement(6040..6686)
                     /locus_tag="RD488_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7094..7597)
                     /locus_tag="RD488_002315"
     CDS             complement(7094..7597)
                     /locus_tag="RD488_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7658369.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7720..8484)
                     /locus_tag="RD488_002316"
     CDS             complement(7720..8484)
                     /locus_tag="RD488_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDT7658370.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVISLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8592..8867
                     /locus_tag="RD488_002317"
     CDS             8592..8867
                     /locus_tag="RD488_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDT7658371.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9305..10255
                     /gene="yidC"
                     /locus_tag="RD488_002318"
     CDS             9305..10255
                     /gene="yidC"
                     /locus_tag="RD488_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7658372.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(10434..10634)
                     /locus_tag="RD488_002319"
     CDS             complement(10434..10634)
                     /locus_tag="RD488_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658373.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
     gene            11439..>12187
                     /locus_tag="RD488_002320"
     CDS             11439..>12187
                     /locus_tag="RD488_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HDT7658374.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTP"
BASE COUNT         3708 a         2536 c         2155 g         3788 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcagcactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aataagaaaa acatctttcc atcggaaaga
     3301 tgtttttttg ctttttctag tttaaataac agcttttttc atctattttc gttatactgt
     3361 ataagaaaaa ggagttgaat ttatgaatct aaccagagat ctgatctttt tagttctcta
     3421 tcttattggg gtattctcta tcgtttattg gcgaaaacag aagaaggatc cttccttgtt
     3481 cttttacggc agtacgtgga catttacggt aatcttaact tattttgtcg tgttggaaat
     3541 tttttattcg accttttatt ttttgattcc attgttgttc tttagtatct ttgctttttc
     3601 ttatttcaca gaaaaacgaa ggctactgaa tggtctttta ttcaatgttt tactcatcag
     3661 tttcggcatc tacttgtttg tcttgctgta tgaaacgcaa aatatttttc ttggcggact
     3721 gatcgccttg atcacgattc cattgctact tgtcctttta tttggtattt atggattgat
     3781 tgtttttctt ttttggaacg gggtcacagt tttacgtaga gaatcgcatt cattagctaa
     3841 tcttttaacg ttgatactag ccatttttct tacactgttt cttgtttttg actttttctt
     3901 gttaaaatat ttgccgcaat ggataaatgc tttgtttttc tgcgttcccc tgatcttgat
     3961 ctatctattt atcgtattct acaacttttt gactgtctca ttcttgtatc agttcaaccg
     4021 gcctcgatac aatcaagact tcatcgttgt gttaggcgct ggattgatca atggagaaac
     4081 agtttctcct cttctagcca agcgaatcaa taaggcaatt gctttttatc gggctcaaag
     4141 ccgtgctaca ttaaatccgc ccatcttatt gatgtctggc gggcaaggag cagacgaaaa
     4201 agtaccagag gccattgcga tgaaacaata tgccatggaa caaggaatcc ctgaaagaga
     4261 cattcttgtc gaaaccaatt cgacaaccac tttggaaaac atgctctatt caaaggaaat
     4321 catggatcag caaatgaaag ggccataccg cgcgatcttt agttccaaca attaccacat
     4381 ttttagagcc ggtctttatg cgcggcaagc caaattgaaa gcaaatggta ttggtgcaaa
     4441 aacagctttc tactacttgc ctaatgcgtt tttaagagaa tacctcgcca tcttgatgat
     4501 gaacaaaaaa agacatatga tcatttgcgg attgcttttc gcaggctccg cattcttatc
     4561 gctgattact ttacttttct aaaaaaacaa ggtgtgacaa aacatatgtc acaccttgtt
     4621 tttttctttc attctcttaa ctattggcaa aaagagtatc ccttttttga ccgctacttg
     4681 ctgagcagaa taaataccgc tgttgcctga acacataaag ctgatcaagc agatcataaa
     4741 gaagtatact gccgcttgtg aaccgaacaa ttcgatcccc atcacaaagc aggcaatcgg
     4801 tgtatttgtc gcaccagaaa atactccgat aaagcccaat cctgcaagaa aaggaacaga
     4861 aacatggagc aaaggcgcta gtgctgcacc aagcgttgca ccaatttcaa acaatggtgt
     4921 cacttctccc ccttgatatc ccgcgcctaa agacaaaact gtgaagaata acttcccaat
     4981 aaaatcatag acatgtgcct gtccattaaa tgattcttga agtaacggaa gactcaatcc
     5041 gagataacgt tgtgtttgca aaatcaatgc tgctgccaca actacagctc cacctatcgt
     5101 atttcgacaa acaggatgag gaatccattg tgcatatcgc gcttttaaaa agacgatcga
     5161 acggctgaat acccaaccaa tcaaaccaaa agcaatccca gcaacaaaaa ctttgaagaa
     5221 cagcaacata ctccattcag gaatcacacc catttggtaa tgtagatgag aaacaccata
     5281 gctttctgtc atgaaatttg caaacagtgc agcaaagaag ctagggaaga tcgcttctgt
     5341 tcggactttc ccgattgcca acacttctaa tccaaataat gttccagcta aaggtgtgcc
     5401 aaatacagaa ctaaaacccg cactgattcc actgataatc aagatttccc gttctgattt
     5461 atccaatcgg aacaaacgtg ccgtattatc tgctaacgct ccccccattt ggactgctgt
     5521 tccttcacgg ccaacagatc ccccaaataa atgggtagtt atggttccaa acagtgtaag
     5581 tggaataagc cgcaacggga ttttttcttc tccaccattt ccttgatcga tcactaagtt
     5641 gtttccacga ctagaaagtc cgccgtgata cgcatagaga taagcaaaaa gcgcaccact
     5701 aactggtagt agacaaagga gccaaggatg tgatagtcgg atatctgtca caactgtcag
     5761 gctatttaag aaaaaagcag acaagctccc catgaatata ccgagaatcg ctgtgatcac
     5821 cagccacttc agcatataca ctaaaatgcg tactggactc ggtaattgtt tttccataaa
     5881 aaattcctcc tcaataaaaa aacgcctact aaagaaaggg gctgtcccca gactttagta
     5941 ggcgtcatta gctatctttc gttagcattt aaaggcgaac accatcacct attcacttcc
     6001 attaaaagat agcatatttt tctgtaaaaa acaataaaat tatcgttctt tctttacacg
     6061 ttcagcaaat tcatagaaag gagccaattt cgttaactgt tgattacatt ggtcactatc
     6121 atgacaaata taattcccct ttttcgtata cgtgccatca gaacctgctt tcgttgtaga
     6181 aagaaaaagc gaaacattcg atgttttctg acagattgca cagattccct tatttatcgt
     6241 tggtgataaa gtaccgctaa tcccttttaa tttttcatct tcgtaataga ccatgaattt
     6301 tttctgcgta cctggatcat tccagccgat gtacgtatgt tcttgcaagt cgatttcatt
     6361 ccaagctggt tgtttgagtt ttttcacttt tcggaataat ttctcgattt gtggtttgct
     6421 aggctgcata aacggctgaa cgatttgctt cagctcctcc aatgctcttt ctgcttgcgc
     6481 ttttgtcagt tttacgtcta aaactgtcgt taaaaatgta tcgattctgg cagttcgtga
     6541 tctaatatgt ctcgaatctt ttcagctgct agtgcctgaa ctgtttgtac cgtttttgga
     6601 tcattgacag atgagtacgc atttaataac tgttctactt ctcttattat aaaaaaatat
     6661 tggtatggtt ttattgtttg ttccatgatt ttaaagtcct ttcttctaac caaagtgcat
     6721 actttgtaga aaaaagtgat cttctgcaaa gtatgtgtta tctgaagatc ccggactctt
     6781 ttaaataaga tacgttttgc atcttatcat cacccccttt aatgcttatt attctatgta
     6841 catgattcat tcgataaata aaagtaaacc gtatcttgaa cagatagtca actgcaaaca
     6901 gaaaaaagga ctgtgacaaa agtcgtgtca aagtcccttg tttcgaatga atggtgttca
     6961 aaagctggca tctgcggtaa taagccgaaa cttcacaaaa atttgagaag caattttcgt
     7021 aaattccttc ttatttcttg aagctgacca cttctgtcac aacctcaata tggtctatta
     7081 ttggttttat ctattaaatc gaggattctt tcccaaagta acgttgccat ctcttacgca
     7141 tacttgctga cataggctga gcggcttctt tgactgcgca gtatttgtct acgaatgtta
     7201 cgatatatcc ttctttgtac ttaggcggtg caatcgttgc gccccacatg tgcttcaaaa
     7261 tgatatctcg ctcaagatcc gacaattcgg tgatcttttc tgcattcttt acagcaattc
     7321 ttggatggat atacgcatgt gtgccttcat caaatttcgt cgtacgccaa tcatagtaga
     7381 acagatcatg caaaagtcca gcacgcgctg ttgctttagc attgccaccc catttttttg
     7441 cgagcagata actatagtaa gaaacactga tggaatgctc caaacgagtg gaatgaacat
     7501 gctgtgtgta attcgctaat tttttcactg cttctgtttc taaaagatct tctacataag
     7561 acatatattc ttcgtcttca cgccattttt ctgtcataat tatcgatctg ccaccttttt
     7621 gaatttcatt ttcttctgaa attgatctaa gtataccacc agtgttcgga ttattctagt
     7681 cgccttggat aaaatagcca aagcttaata gttccttaat cataaagaaa aatgataaag
     7741 aacaatccct gccgcaaccc caacattcaa cgattccgca tttcctttca tcgggatata
     7801 tacgttctga tcagtcaaag acaagatttc ctgacttacc ccctgacctt cgttccccat
     7861 gattattgcg aagttatctg atttttctac tttgtctaat gcgtgtgctt cttcatttaa
     7921 ttctgtgcca tacactgtaa accctttgtc tttcattaaa gaaatcactt ctgtcaaatc
     7981 tttttgcaac acaggcaaat gataattgct tccctgcatg ctgcgcagca cctttgtact
     8041 ataaatatct gccgttcctt tgcctaataa aacaccagcc atatcaaatg catctgccgt
     8101 acggatcatc gtccctacat ttccaggatc ttgtacatta tctaacaaca gccatcctcc
     8161 tgaaaaatct ggcgtgcctt cagccgttaa cgccatcact gctaagattc cttgtggtgt
     8221 aggtagatcc gatacagcat ccatgacctc atccgaaact agaaaagtag aaatctcttt
     8281 gtttgcggcc agccagtctc cccattcttt catgcctcgc tgtgtcacaa aaagttcttt
     8341 tatttctgca tcagacgacg cagcttcttc aatcagatgg aacccttcca aaagatattc
     8401 ttccttttct tcccgatatt tctttttatg tagttttttt aattctttga ttcttggatt
     8461 ttttgctgat tggatctctt tcacattcct cacctcccca tgattatatc atggaatagg
     8521 tgcttgagct tgtttcatcc taaaaaaatc ggtatcatta atttataaaa taggaaagaa
     8581 aggtgacgaa catgcgcaaa gttaaaatga acgtccaagg acgcgtccaa ggcgtaggat
     8641 ttcgctacat gaccaagatg gtcgctgatc aactaggcgt gactggaacg gtaaaaaacg
     8701 aagatgacgg ctcagtcacg atcgaagcaa tcggcaatga cgacatcatc cagaaattta
     8761 ttgaagaagt caagaaatct ccgagcccaa gtggacgagt gcagtatgtg gatgtccaag
     8821 aagacccgat gattgaggaa cgaaagaaat ttgatgtggt gggataaggt tgtgaaaaag
     8881 ctggtctgca tcaagcatta aggacaggtt gtgaaaaata gctctccata tttttcaaca
     8941 ggctggactt aatgccgtag atgcaagctt ttgaacaccg tcgataaggt tattcttgag
     9001 gcgctttgcc tcaaaaatta aggacagcag tgaaaaagct gatctatcac ttgcagtgag
     9061 ttcatttgac tccgcttttt cgggcagaaa aaaagttttt agtttattaa agtaagaaag
     9121 aaacacttgg aatcattcta ctttttccta gtatttcttt cttgattttt tgtctttttt
     9181 tcaaaatttt tcgctacgta aaagaacgaa tatttatatg aaatttctat gaagttgatt
     9241 gaattccatg cgctttttta gtatagttaa gtttgtgtaa aaattataga agaggaagta
     9301 ttctatgaat aaatggaaaa actggttatt gggatccgga cttgtcagta tcctgctctt
     9361 tttatctggc tgtgtgcgga tggattcaaa cggaaaccct gacacttcgg gaatcgttta
     9421 tcgagtactc gtccatccta tgggccaagc gattacatat ctagttgaaa atttcaattg
     9481 gtcttatggc tgggcagtta ttgcaatgac tgtgatcgtc cgtatcatca tcttgccact
     9541 aggtattagt caatcgaaaa aaacaatgat ccaatctgaa aaaatgcaag cgttaaaacc
     9601 acaagttgaa gcagcccaac aaaaattgaa agctgcaaca acacgtgaag aacaaatggc
     9661 agcacaagca gaaatgcagc aagtataccg cgaaaacgga ttgagtatga ccggcggaat
     9721 cggctgtctg cctctattga tccaaatgcc gatcttctct gccttgtact ttacggcacg
     9781 ttatacagaa ggtatccggg aatcatcttt ctacggcatc gatttaggct caccaagtat
     9841 ggtacttgtt gccattgcag gggtcgctta tctgcttcaa ggatacatct caacgatcgg
     9901 tattcctgaa gaacagaaaa agacgatgcg tacgatgctg atcgtctctc ctgctatgat
     9961 cgtcttcatg tcgatcagtg cgccagccgg tgttacactt tactgggtag tcggtggtgt
    10021 gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg aaaccacgtt tgaaagcaca
    10081 agtggcagaa gagttgaaac aaaacccacc aaaacaagtc gtcactccaa gaattgatgt
    10141 gacagaatca gctaaaccag ctgacagcaa acaagcaacc aaacaaatca agcaacccaa
    10201 aaacagtaca aacaataaag gccgcaacgc aggaaagcag cagaagcgga agtagatagt
    10261 aaataagagt gtaataaaaa ttcattaaca gttttagcaa ttaaaaatat cgaccaagat
    10321 ttttgaaaaa gaaatctggt cgatattttt atttaagtga atgtttaatt tgaatcatcg
    10381 attgatcgct atctaattgc agcagcatct ttttatgaag aaacaacttt ttcttatcta
    10441 tcaacgtaga caggtgttgc tgtttcttct aatagtgtac ttaattcctt aatattttgt
    10501 tttccttctt ctaacatcca actactcgct ttttcttcgc cttcggtaac aaaaggcgcc
    10561 actcccttcg cccatgttgc tcgcccacat aagacaccat tctccataaa ggacaacgcg
    10621 gagataccac ccatctaaat aacatccata aacctttcta gtagaagaat agtgatagta
    10681 tccatccctt tttctactgg gaatacaatt acacgattca aagcttgata cacaacattt
    10741 cccttcttat aaaccgctat tgtaaccgaa ttgttttgaa tcaccttttt gggatagaaa
    10801 ctggctcctt tccgcaactt cttaaatgtt ggtttctttt atactttctt tgtagcaact
    10861 acaaatttct tcaaatctct aaatgtttgc ataacaaccg cctttctgac ttttactcag
    10921 gatggtattt aaaaatcagc aaaataaggc ttctctccat cttttttatt tcctagctgc
    10981 tttaaagaca ctcttgctgt tttttaatct ctatcaaggg ggctctgaat ctattttgat
    11041 gaacttatct tattaatttc tcaaatgagc tgtcagacac aactgtattt tttcaatctc
    11101 ataccggaca actatgccag cttaaaaaaa tttcctctgg caaaacttct ttattgaaaa
    11161 atgacaatga aaaaagacca ttctttttgt tgaatgctca ttgtgtaaac atatttcctg
    11221 cgactgctct tcgaaccatt ctcagtgcaa tccctaattt atctattaaa tcttctttta
    11281 gttcctcatc tttcatattc aaaatttcct ttgtatgtta cacaagtttg ttctctaaat
    11341 aacgcgaatt gtaaaattaa gttagaaaaa taaaaaggca tttatggtac actcaaattg
    11401 tatttccgac gaaagaaaac aaaggagtgt aaccataaat gacctacaaa catcttacca
    11461 tagacgaact gacaatgata gaatcatatt atcttcaaca taataagccg gttgaaatcg
    11521 ctaaccgaat gggacgtgct atacaaacta tttataatgt agtcaataag ttcaagcaag
    11581 gtaagactgc tcttgattat tggcaccagt ataaagaaaa taagaaaaaa tgtggtagaa
    11641 aagtcattca attacctgct catgaagtag attacattaa agagaaagtc actcttggtt
    11701 ggacgcctga cgtcattatc gggcgaaaag aaaggcctgt ttcatgcggt atgagaacac
    11761 tttatcgttt attttctaaa ggaatatttg atattgacac actaccgatg aaaggtaaaa
    11821 gaaaacccaa tggccatcag gaaaaacggg gaaaacaaca gtatcagcgc tcaatccatg
    11881 atcgacctga taattatcct gatttcaatt ctgagtttgg tcaccttgaa ggtgatacga
    11941 tcgttggcat tcatcataaa agtgccgtca ttactttagt tgaaagatta tctaaagtca
    12001 ttatcacgat taaacccaac ggccgtaagg cattagatat tgaaactgcc cttaatcaat
    12061 ggttttctcg cttccctaaa aacttcttta aatctattac gtttgactgt ggaaaagaat
    12121 tttctaactg gaaagccatt agtaaccaac atgatattga tatatatttt gcggaccctg
    12181 gaacacc
//
LOCUS       DAPBBR010000071        11304 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPBBR010000071 DAPBBR010000000
VERSION     DAPBBR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.074"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            5..610
                     /locus_tag="RD488_002321"
     CDS             5..610
                     /locus_tag="RD488_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7658375.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            630..992
                     /locus_tag="RD488_002322"
     CDS             630..992
                     /locus_tag="RD488_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658376.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            995..1177
                     /locus_tag="RD488_002323"
     CDS             995..1177
                     /locus_tag="RD488_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658377.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            1194..4613
                     /locus_tag="RD488_002324"
     CDS             1194..4613
                     /locus_tag="RD488_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDT7658378.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            4664..5401
                     /locus_tag="RD488_002325"
     CDS             4664..5401
                     /locus_tag="RD488_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7658379.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            5411..7702
                     /locus_tag="RD488_002326"
     CDS             5411..7702
                     /locus_tag="RD488_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7658380.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            7726..9816
                     /locus_tag="RD488_002327"
     CDS             7726..9816
                     /locus_tag="RD488_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658381.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGKPNLMSKLKSSDFN
                     VGYHGSLTLDNEKLHFTSDGTGSIIMFTRINTPQLTSGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFVD
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDAPYYLSKVALGENLIKPESQQPVTNSNY
                     LINTYNIKPMVKGKKYTITLEGTKPATQVFRPFFTRATGDAWEVGDLQPVEGLTNVWS
                     KTFTAADDSHPTTPQVQIYQVPSTSVGQCTIKWLKLEEGNTRTPNISEYKYRGTGMRD
                     SNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTT
                     AKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFV
                     ALNGKRSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNS
                     SYGSAYSFVITYSI"
     gene            9830..10177
                     /locus_tag="RD488_002328"
     CDS             9830..10177
                     /locus_tag="RD488_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658382.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKSGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            10170..10310
                     /locus_tag="RD488_002329"
     CDS             10170..10310
                     /locus_tag="RD488_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7658383.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            10380..10799
                     /locus_tag="RD488_002330"
     CDS             10380..10799
                     /locus_tag="RD488_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDT7658384.1"
                     /translation="MEKYLNTFSVMTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTG
                     LAKAWKLKEISSEIGFEGLLKKVLIFVVIAVAVEVQKIVGNSIPLREIVIMFYVANEG
                     ISFLENISVFLPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            10796..>11304
                     /locus_tag="RD488_002331"
     CDS             10796..>11304
                     /locus_tag="RD488_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HDT7658385.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYTINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVT
                     QNIWGDHTDP"
BASE COUNT         3989 a         1721 c         2390 g         3204 t
ORIGIN      
        1 aacaatggct aaaacaacaa cagtaacaac ttttgacaat ataagtatta aaagaatttc
       61 ttttaatttt aagaatgcaa caaatgcaat ttcaactgat tgtaatggac aattagatgg
      121 cgaaacagaa atgcagagaa ttgtaaaaaa atgcggttca acagaagtaa aatcgaaatc
      181 taaaccaatc aatatgacgg taacaattac tgcacatgta ccgatggaag tttatcgacg
      241 cttcaatggg ttgaaacaag atgaacgtat taaatcggga atttactctt atggtcctga
      301 ttccgtaggg gaagatttct ctcttgctgc agagatcgtg gatgatttcg aagaaaaaaa
      361 taagctgatt ggtatgttag catgcacttc gaatacagga ttaacattct ctattgaaaa
      421 tggtgcggat gaagtagctg cgttagaact agaaacaaaa gttatgcaag atgaatttgg
      481 taaattttat catgaagcaa ttgttgcaga acttgaagaa gacttaacag atcaatggat
      541 gacgaatcta tctgctgatg tgattaaaaa aacttcagtt gtgacaacta cggccactca
      601 atcacagtaa aaaaaacgga ggtagcgaaa tgaacgaaga ttactcaaaa attgaactaa
      661 acgatggaac aattttgaat ttagaaccta aactgaatat caagaaatta ttgatgatca
      721 atagagattt taacacagac gagtttgcaa aaatgactgt gggaaaagga tccatggata
      781 tttctgttat tcaaggtgca aaggctgtgt atattgctta ccgccaagcg aacatgactg
      841 attatatttc attcgatgaa tttatcgata aatgggattt tgatatggct actgccagct
      901 atatttatca attgatgatg ttcaaacaag cacgcgatgc ttatcaaaaa gaatttgaaa
      961 aagcaaataa ggaaaaaaag cttcaaaagt aaaaatgcca aagctcttag ttgaaacgtg
     1021 ggtcgatgtc tattcgatgt tgaccgacgt tttttctatg ccttcagatt tggttttaag
     1081 cgatatctgt ttagatgaca ttttgcaaat ggcttacaac aagagtgctt atgaaggatg
     1141 gaaaaactat gcaataaacc aatcccagaa aaactaaaga aaggaggtaa aaaatggcta
     1201 aaaagagaac agaagcagaa gtaacattca tagctaacga tgacggattg aaatctacgt
     1261 taaaagaaat cagtgctgaa ttaactaaaa atagagcaga attaaaacta gaacaagctc
     1321 aattacaaca gactggttct gaatcagaca agttaggaag taaattatct tctttagaaa
     1381 agcagtatga attacaaagt caaaaagttg aagtaactag ccaacgttta gccaatgcca
     1441 aaaaatatta tggagaaaat tccaccgaag ttcagaaact tgagagagaa ctgattaacc
     1501 aacaaacagc gcaacaacgt ttgtcaaacg aaattgataa aacgagtaat gcactagctc
     1561 aagcaaaagg cgaaatacag acgtacgagt ctacaatgca acagttggat agtgaacaaa
     1621 aaaatgttca agctagtgct tctctgattg aatccgaata caaaaaatgg caagcaactg
     1681 ctggtcaatc agcttctgaa tccgagaaat tagcgaaagc ccaagaatat gtttctcaac
     1741 aatctgaaaa tgcagagaaa acgatagata tcctgagacg acagttagaa gctacacagt
     1801 ctgagtttgg cgctacatcc acagaagcaa tgcagatgga ggcgaagctt aatgatgctg
     1861 aacgtgaatt tgaagagtta ggacaagctg ctaaaaatgt agatacaact aacttggacg
     1921 atatcggaag caaaatagat atgaataatc taatggaagc ttctgacgtt ttaagcgaca
     1981 ttggcgataa gcttacagaa ttagggaaac aagcagtgga ctctgctaat agtgtaggta
     2041 gttcccagag taaaatacaa gctaattttg gtttgactaa acaagaggct gaagaattaa
     2101 cgaatgtagc cagagacatt tattataaag gttttggaga atcgttagat cagtccacag
     2161 atgcattgat tttggtaaag cgtaatttag gcgatttaaa taatcaagat ttacaaaata
     2221 tcacggaaca agctatggtc ctagaaaaca ccatgggcgc tgatatggat gaaacgttac
     2281 gtggtgtaaa tggcttaatg gtcaatttcg gcttgagcgc tcaagatgca atggatttaa
     2341 tggtttcggg tactcaaaac ggtttagata aaacgcacga attaggcgac aatatggcag
     2401 aatatagcca attatggagt caaatgggat attcagctga tgaaacgttc ggaatgcttc
     2461 aaaatggttt agatgcgggt gcttataacc ttgataaagt caatgactta gttaaggaaa
     2521 tgggaatatc gttaacagat ggtcgatttg agcaaaacat ggatatgttt agtgaaagta
     2581 ctagaaaagc ttttgaagag tggaaaaatg gcggaggaac acaaaaagac gttattaatt
     2641 ccatgattca agattttagc aatatggatg gtcaatacga ccaattaaat aaagcttcta
     2701 caatttggtc tgcacttggc gaagataacg cgatgaaagt tgtccaatct ttgactgatg
     2761 ttaaccatac atttgatgat gttagtggat ctgcacaaaa aatgaatgaa gattctacta
     2821 ctccgttaca agaattaaac ggaaaaatag ctgaattaaa ggattcatta gctcctatag
     2881 gcaacacaat catagatgca ctcgaaccag taattgattt tctaggaaag atggctgatg
     2941 cgtttaataa tcttccacaa ccagtacagg attatgccgt agcgattggc ggattgactg
     3001 ctgcatttac tttattaatg ccaataatag ttggcttcat ggctctaggt ggtcctacta
     3061 cattaataat aggagcagtt attactgtta ttgctggagt tatagcaatt ataaaaaact
     3121 ggggcgcaat tactgactgg tttaagggaa tatggagtaa attcactgat tggttgggtg
     3181 gtacttggga aagtataaaa gaaggtgcct catcagtttg ggatggagtt aaagaaacct
     3241 ggtctggatt tgtagattgg gttcaagata tttggcaagg agtttctgat tggtttggag
     3301 agctatggag cggattagtt gaaggagctt ccaacatctg gcaaggagtc caagagactt
     3361 ggcaagcatt cgttgattgg gtttcaaata tttggaacgg agtcaaagaa gtatggtcga
     3421 ttatttgggc agacattgta ggaattgttc aaataccatg gaccttaata acgtcattga
     3481 ttcaagccgg tattaatatt atcgtgggta tttttgatgt agctggacag ttattaggcg
     3541 cagcttggca agctgtttgg acacctattt ctgatttcct taaaaacact tgggatacta
     3601 tgacacaatg ggtaagcatc gcttggaatg gaattgtaac tacattccat actatatttg
     3661 atccagtagt ggcatggtgg aatggtatat ggacagctat tagtactacg gcttcaaata
     3721 tttggaattc aattagtgca acagcttcta gtatttggaa cagtatcaag aatacaatca
     3781 ctagcttggt acaagcagct gctacagtaa ttcaaaatat ttggtcaact gtatctagtt
     3841 ggttaggtgg aatttggaat tcaatcagct ctacagcatc aaatatctgg aatagcgtga
     3901 ctagtagtat aagcaatgct ataaacgcag ctaaaagtgc cattcaaagt gtttggaata
     3961 gtatatcttc gtggatcagc ggaatttgga acggtatcaa aaacactgct ttgaatcttt
     4021 ggaatggaat tacaagcact attagctcta aagtaaacga tggaaaaaat gcaatttcaa
     4081 gcggttggtc caatctaaca ggtattgttt ccgacatatt caataatgtt aaaagtacaa
     4141 ttgctaacat ttgggaaggt atcaaaaaga ctgttagcgc tccaattgat tggatcagag
     4201 ataaaatcag tagtatcttt gataatttga atatttctat accacatatt ccgttaccac
     4261 attttaaatt gagcggagaa ttcaatccat tgaaggggaa aatcccaacg ttgggtgttg
     4321 attggtatgc gaaaggtagt gtgtttaatt ctccgaatat tatcggtgtc ggcgaagcag
     4381 gacctgaagc agttttacct ttgaaaagat ctgtgctgca agaaattggt gatcgtatct
     4441 tgagtagcac atcagtttca tctagggcac aaacgattca acctgtgaat aactacgaat
     4501 tcaatttcac aattgatggt aacgcagatg aggttactat gaagcaaaca actcaacaaa
     4561 tcattgatag cattacaaaa gttcaaaatg ataatgcttc ggcatggcgt taaacaggag
     4621 agtatttctc ctgttttttt agtattaaaa aggatgtgaa aaaatgactg attgtataca
     4681 ttctataatc gatggatttc ctgattattt gcataaattg gctttagctg aaagaccaac
     4741 cataccttct ccaaaaagac agagagttga aacttctgtt ttaggaaggt taggtggctt
     4801 agtacaagat tactcgtttg aagacatgtc gtttacattg cactataact atttagagga
     4861 tgtggaagac catcaagcgt tcaagcaatc gttttatatc atgcgtcatt ggttaaatta
     4921 tgcaaagaaa ttagaattct ctgatgatcc caacgtctat tatgttatcc agactatcga
     4981 tattggggat gcagaaaacg atattgttga atggggagag ttcgatgtaa atattactgc
     5041 gaaaccattc gcaagagttc aagaagatgt acctataacc gtagataaac cacagtcatt
     5101 taacttgctg aataatagtt tagaagaaag ttttccaaag attatcatca ctccttcagc
     5161 tacttcatgc cagttcatct taaatgatta tgtgtttagt tttgaaggct tagtagtagg
     5221 aactgacgta gtcattgata gtgatttgat gctttgctac gaagagcaat cggacggaga
     5281 tattttagat cggtccaaca aaatgaagac catgcaatat ccgacattgc aagtggatat
     5341 taattatttt aattgtactg gtttgagcaa aatacaaatt tatcgtaatg ggttaaggta
     5401 ggtgaaatag atgatcgata atttaataac tatttacgat aaaaacgacg cgaataattt
     5461 agctgaacat ttatatgata cgcaaggttt aggcgctttg tcagactggt taacagctac
     5521 tgttagcaat aaattaaacg gagccgagat atttcagggt acttatccaa taagcggaac
     5581 taatgcagat ttgattgtag aaggacgtat tattcagtgt tatgtagatg aaaatcgagc
     5641 aaaacagcgt ctacggattt attatgcaaa gacttctgta ataggcaata cgatagaagt
     5701 aaaagctgaa cctattttca atgatataag aaaatcggtg ttgaataaat atgacagtgg
     5761 aacagaaaag atcactgcta gtcaggcatg gcaaaacgca aaaactttag cgaaaccagt
     5821 tattccttca cagttttctt tctcgtcatt agtagatacg cttgctaatg tgaagataga
     5881 aaaggcgaat tttttagaat tctttggtgg aaaagaggga tctattctag atcgatttca
     5941 tggggaattt ctaaaagata ataacacatt acgtcatgaa aaaaggctag gcacggatca
     6001 taaaatcaaa gcgatttata ctaaaaactt aactggtctt gacttagaga ttgatgctca
     6061 aagtgtttta gttggagttt atccattcat tagcagctct tcagaaggag aagacgagat
     6121 cactctacca gaagaagtta ttttcacgga ttacgtggat gattatcctg ctggatatgt
     6181 ttcttttgtt gattttaaag acaaagcgac tgatgtagcc acattaaggg aagctgctaa
     6241 agactggttg aaaacaaaca tagataaaca aaaaccacaa gtgagtggtt cgattgaatt
     6301 agtaccattg aggcatcaaa gaggctatga aaaatttgtt gatctagaaa aagtttcgat
     6361 gggtgacgga gtagatgtgt atcatccaca gttaaaagtg aatatgtcag cgagaattgt
     6421 ggaatatacg tttaatgttc taaccaattc atacgataaa ttagttgtag gaaacgtcaa
     6481 aacaaacttc ttagaaaaca cagagaataa tgtcagcaat ttgattaatg atgccattga
     6541 tcaattgaaa aacggtggcg aaatcagtga tttactcaat gatattgtag atcatcaaac
     6601 tgatatgatt actggtcaaa atggtggtta tgttttatta gatcctaaag aagcgcctag
     6661 tcgtattttg attatggaca caccagataa gaataccgca aggaatgttt tacaaatcaa
     6721 caatgctggt attggttttt ctaaaactgg cattaatgga acatatgaaa cggcatggac
     6781 gttagatggc ggattcaatg cctcgtttat tacggctggt gaaatagtag gaattactat
     6841 tagaggtact acattaatta gtgatggtgc tgattataga acaagtattg ctaatggcaa
     6901 aatgacttgg tactcaaaaa aagttaacaa agatattatg gagctagaag cacgtgatta
     6961 tgtaagtgct gatgccggta ttgtatcata caccatgaaa actggtggtg gtttcatgat
     7021 tagaaatcca cagggtaact tggtttttag tacgtgggat aatggtaata acagaccgtt
     7081 tctatctttt ggtgcgccca atttcaggta tagcaatgct agttatgtaa cttctggcga
     7141 cggtagttct ttaagcatta atggtagtgc gggtaactca tgggaattta aggtagctgg
     7201 taggactatg aaatttacta gtgatggtat gctaacgtta ccaggttgtt tttttggttc
     7261 atgggaagat gggaaacttg ctaggtttga acaatcaacg gtacaagtat ataaagattt
     7321 tactgttaga ggtactaaaa actcaactgt accaacagaa cattatggac aacgactatt
     7381 gaacgcttat gaaactccag aatattattt cgctgattat ggggaagccg ttacaggtga
     7441 cgatggtaaa gttcgtgttg atattgaccc catgtttgct gaaacagtaa atctaagtcg
     7501 gtatatgaca catgtgacac ctacagaact agttttgtgt gctgttactc atgaagatat
     7561 tgaccatttc atcattgaaa ctagtaagcc aaacgtatta gttagatgga atttagtggc
     7621 acaccgtcta gggtatgaag atattagatt aaaagaggat acagcatatg atagcacagt
     7681 gcttgaccaa aaacgttttt aaaacgaaga caaggaggta tataaatggc tagcagttta
     7741 tataatttgg ctttagattt cagcaaagaa ttaaactaca ccaaagctat tatggctcgt
     7801 caaggtgata aagggattac ggtgacggtt aaaccgtttc taaatggctt gcagatggat
     7861 acgagtggcg gaacatttac tttaaaagga acaacaccat ctaaccgtta cgtagataat
     7921 gttgcaacta gtgtaactag tgaagaagtc acgttttctc ttgatggcac atttatgagt
     7981 gaagcaggat attataaaca ctgctacgta gaatatagaa aagacaatca aattttaaca
     8041 acgcaagata tcattttttt ctcactagga gtgtctgaca tttcgcaagg ccaagccgat
     8101 gaatatgttt cgcaattaga agagttgatt cgaaagtaca acgaaacttt tgatgctttt
     8161 atggctgaaa tcaaaggtag agtggatagc ttaaatcaac agattactga tttaactggt
     8221 caagctaaaa cgctacaaga caagttagat gctctgaaag aagaaatttc taagttaggt
     8281 aacttacaag tgatgtacag taacagcatc gacttcgggg gatatgatta tagcggtaag
     8341 ccgaatttaa tgtccaaact aaaatcgagc gattttaacg ttggttacca cgggtcacta
     8401 actttggata acgaaaagtt acattttact tctgatggta caggaagcat tattatgttt
     8461 acgcgtatta atacacctca gcttactagt gggaaaacct atactctgag tgcgaaagtt
     8521 cgatttgatg aaggaactac aggagctatt gataaattac gtttggtgta tcgtacatca
     8581 ccaggagaaa agatattatt ggaagcaaat agtacaaata ttacaacaga tgatgtaggg
     8641 aaagaaataa caatcaaagg tacagctaac gttaattatc aaatcacaaa tttagatcga
     8701 ttttatatga gtattagctt tgttgacagg gataaaataa atggcggatt taagttgtac
     8761 gacatcaaaa tcgaagaagg ctcaacagcc acaccgtacc agcctaatct acttgatgca
     8821 ccgtattatt tgagtaaggt ggctttgggt gagaatctaa ttaaaccaga atcacaacaa
     8881 ccagttacta atagtaacta tcttattaac acctataaca ttaaaccaat ggtaaaaggt
     8941 aagaagtata ccatcacact tgaaggaact aagccagcaa cacaggtttt tagaccattt
     9001 ttcacacgag caacaggaga tgcatgggag gttggtgact tacaaccagt agaaggctta
     9061 actaatgtgt ggtctaaaac atttacagca gcagatgact cacaccctac taccccacaa
     9121 gtgcagattt atcaagtacc aagcacaagt gtaggacaat gtacaattaa gtggttaaaa
     9181 ctagaggaag gcaatactcg aaccccgaat attagtgagt ataaatatcg tggtactggt
     9241 atgcgtgatt caaacaatcc aaaagattat gtttgggatc tagcaccaga atatgtcgaa
     9301 gataatttgg ccacagatat taaaatttct gaaattactg gtaaagcaaa caattatacc
     9361 gatgggaaag tatcggagat taattcgcag ttgactgctt caattaatga agtagacacc
     9421 acagctaagg atgctcaaac aaaagcgaat gctaatgcga ctgctataga tgaattagac
     9481 aataagatcg atgaacgcat taatgataca gctactacca cattaacagt tacaaacggg
     9541 aataccggat cagcaaagct ttatcgtgaa ggaaaaacag tttctatata ttttgtggct
     9601 ttaaacggaa aacgcagtgg tggaaatgat tcaacgatac taacaattcc agaaggctat
     9661 cggccaccaa ttagttttga acaactggtt gggtcaatag accgttctac tttgaacagt
     9721 gctcaactat ctattggcgc agacggagcc attaaatgga gaagaaattc aagttatgga
     9781 tcagcttatt catttgttat cacttattca atttaaggga ggaaatctaa tgaaagtagt
     9841 ttacaaatca atcaagcctt acggattcga gcaaatcatt ttgaacaatc aagaaaatat
     9901 ccctgaaaac tgtacagaga ttaaaccacc agttcctaac tggagaccaa gatttgattt
     9961 tgataaaaaa cagtgggttg agttagctac tgaagaagag aagagtggca cagcggttga
    10021 cgatattgaa gatgtcgatc agttgaagca attaaatgct ctactgacaa aacaattggc
    10081 gatatcggta caggaacaag aaaaaatgca acaaatgtta gctcaattga cgatggaagt
    10141 cgcaagtatt aagaatggag ggaaaagtaa tgaatagttt tccgggcttt gaaaatataa
    10201 aacaatttta tgattgggga tgttatacgg accaagattt acttgactat gtaaacatga
    10261 actgtttaac aaaagaccaa tataagcaga ttactggaaa tgaaatttaa ttaagcacaa
    10321 agttaaataa aaagcgtact caaacgagtg cgcttttttg cataaaggag aaatagatat
    10381 tggaaaaata tttaaataca ttctcagtaa tgacaggggt gataggcggg acaattgttg
    10441 gtttattggg agggatggac aatatactac atgttttaat ttttcttgtg ggtgtggact
    10501 tcttaactgg acttgctaag gcatggaaat tgaaagaaat aagtagtgag ataggtttcg
    10561 aaggattgtt gaagaaagtc ttaatcttcg ttgtgattgc cgttgcggtt gaagtacaga
    10621 aaatcgttgg gaattctata cctctaagag aaatagttat tatgttctat gttgcaaatg
    10681 aagggattag ttttttagaa aacatttcgg tattccttcc tttgccagat aagttaaaag
    10741 aggtattcca acaaatacga aatgatactg aaaataaaga ccgaggagga accaaatgaa
    10801 aaagaaaatc tttgtaggag ctattatagc tcttttttta ttgccaataa acgcctttgc
    10861 ttacacgatc aacaatgaat tcaatttggg cgcaaacgaa ggtagttctc aagtagcaaa
    10921 taaccaatac atcctattgc atgaaacagc aaacgaaact gcgacaggac gaaatgaagc
    10981 gcagtacatg aaacgttctt ggtacaatgc ctatacagcg tatattgttg gcgatggtgg
    11041 gatcgtttac caagttggac aacctggtta tgtacaatat ggcgctggtt catatgctaa
    11101 tgcaaatagt cctgtgcaaa tcgaactgca acatacgcac gataaagtaa cgtttgaaaa
    11161 gaactacaag gcatacgttg aattggctag agattcagca atgaaatatg gtattccatt
    11221 aacattagac acgccttata accaaccagg aatcaaatca catttatggg taacacaaaa
    11281 tatctgggga gatcatactg atcc
//
LOCUS       DAPBBR010000072        11131 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPBBR010000072 DAPBBR010000000
VERSION     DAPBBR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.075"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(51..1517)
                     /locus_tag="RD488_002332"
     CDS             complement(51..1517)
                     /locus_tag="RD488_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDT7658386.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1904..2500
                     /locus_tag="RD488_002333"
     CDS             1904..2500
                     /locus_tag="RD488_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7658387.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2558..3040)
                     /locus_tag="RD488_002334"
     CDS             complement(2558..3040)
                     /locus_tag="RD488_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658388.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3146..3343)
                     /locus_tag="RD488_002335"
     CDS             complement(3146..3343)
                     /locus_tag="RD488_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658389.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3638..4396
                     /locus_tag="RD488_002336"
     CDS             3638..4396
                     /locus_tag="RD488_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7658390.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4456..4884
                     /locus_tag="RD488_002337"
     CDS             4456..4884
                     /locus_tag="RD488_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658391.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4930..5002
                     /locus_tag="RD488_002338"
     tRNA            4930..5002
                     /locus_tag="RD488_002338"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4963..4965,aa:Gln,seq:ctg)
     gene            complement(5152..5523)
                     /locus_tag="RD488_002339"
     CDS             complement(5152..5523)
                     /locus_tag="RD488_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7658392.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5738..5923
                     /locus_tag="RD488_002340"
     CDS             5738..5923
                     /locus_tag="RD488_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658393.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6006..6194)
                     /locus_tag="RD488_002341"
     CDS             complement(6006..6194)
                     /locus_tag="RD488_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658394.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6218..6481)
                     /locus_tag="RD488_002342"
     CDS             complement(6218..6481)
                     /locus_tag="RD488_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658395.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6639..6896
                     /locus_tag="RD488_002343"
     CDS             6639..6896
                     /locus_tag="RD488_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDT7658396.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6967..7158)
                     /locus_tag="RD488_002344"
     CDS             complement(6967..7158)
                     /locus_tag="RD488_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658397.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7299..7619)
                     /locus_tag="RD488_002345"
     CDS             complement(7299..7619)
                     /locus_tag="RD488_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658398.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7642..8076)
                     /locus_tag="RD488_002346"
     CDS             complement(7642..8076)
                     /locus_tag="RD488_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7658399.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8411..9049
                     /locus_tag="RD488_002347"
     CDS             8411..9049
                     /locus_tag="RD488_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7658400.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9373..9456)
                     /locus_tag="RD488_002348"
     tRNA            complement(9373..9456)
                     /locus_tag="RD488_002348"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9420..9422),aa:Leu,seq:cag)
     gene            9984..10484
                     /locus_tag="RD488_002349"
     CDS             9984..10484
                     /locus_tag="RD488_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658401.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10674..11018)
                     /locus_tag="RD488_002350"
     CDS             complement(10674..11018)
                     /locus_tag="RD488_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDT7658402.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT         3519 a         2178 c         1779 g         3655 t
ORIGIN      
        1 aaaaacagga actgctgcaa ataagcaatt cctgttttta tgttcattga ttaatgaata
       61 gagcccatta gttttttgat tggttctttc acagtaaata gcaagatacc accgacgatt
      121 gctactgcac cgataatacc gaagtaagca gattctgttc ccggtgtgta gaagcgtgca
      181 atttgtgcat tgattgcttg tgaagaagca tcagctaaga accaaatagc gattgtttgt
      241 gattcaaatg ctcgtggtgc taattttgtt gtcacagaca aaccaactgg tgaaagacac
      301 aattcagcaa taaccacgat gaagaaactt cccaacaacc acaatggact tacttttcca
      361 cttgtaccat aaagcatacc cggcaacatc aatagcaagt acgataatcc tgcaaataaa
      421 agtccaagag agaatttcac tactgtagat ggttgacgtt caccaagttt cgtccacatc
      481 gttacgaata ctggtgtcag aataaagatg aaaattggat tcaatgattg ataccagctt
      541 gcttggatcg ttacaccaaa tagcgtagat tgtgtacgtt cactagcaaa taaagctaag
      601 atagatgaac cttgttcttg taatgaccag aaaatgattg ctgcaaggaa taatgggata
      661 taagcccata ctcttggttt ttcttcagca gttacatctt ttgaagtcag cattttgata
      721 aagtaataca acggtaagat aatccccaat acactgattg tattgacaaa aaagtcaatt
      781 gtcagatgac cagttagttg tgccccgccg aatactgcag cgataacaac aagtgcgatg
      841 atcaagttac ggatgaatcc tttacgttct tcagttgtca aaggattcgg cggtgttgta
      901 cccactccgt ctaatgtctt gcgtccttgg atgatgtatt gtaataatcc aaagaacatc
      961 ccaatagcag ctaaagagaa ccctaaatga tagttatatt cttgaccgat tgtaccaacg
     1021 attagtggtg ctaataatgc ccctaagttg acacccatgt aaaaaatcga aaatcctgca
     1081 tctcttcgca agtcagtctt tgaataaaga tgtccgacca tgccagaaac atttggtttc
     1141 aaaaaggcgg ttccgataat aatcaatgcc atcgaaacaa acaatgtact tacaccaaat
     1201 ggtaaagcca agacgatgtg gccaagcata atgaaaactc caccgaagaa tacagtgcgt
     1261 tttgctccta acactcggtc agatacccat ccgccgacga tactagacat gtagatcaaa
     1321 gatccgtaga tcgacatgat agctaatgct gttgctcgtg gtaatccaag tcccccgttg
     1381 gcaactgtat cgtacatata atagataagt aatgcacgca taccgtaata actaaatcgt
     1441 tcccacatct cagtgaagaa caaagttgac aatcccttcg gctgcccgaa gaagcccttg
     1501 tcttgctgtt tttccataat ctatacccca attctttaaa ttttcagaaa atattataca
     1561 tctttaccga aaaatttaac taaaaaactt atttaagaaa tataaactaa ttttctataa
     1621 aagcaagtaa tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat
     1681 atatcagctg tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa
     1741 ctaagaaaat ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat
     1801 tttttgtgag catatctgtt tacttacttt ttgtaaggtg ctatacttca tttcgtaatc
     1861 aattaaaaaa atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga
     1921 cactttgaaa aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga
     1981 agaattaaca actttgatca aagaagcaat taaagaaagc ccaactgctt tcaatgctca
     2041 atcaacacgc gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga
     2101 agaagcactt cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc
     2161 tggtttcaaa aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg
     2221 tctacaagaa caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa
     2281 cggaatcgca acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt
     2341 gcaacattac aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa
     2401 ctggaaacta cgttcgcaat tagtattcgg ttcaccagaa acaccggctg gggaaaaaga
     2461 atacatgaac gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac
     2521 agaggttgtg acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat
     2581 caatctctgc ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg
     2641 cagaaaattt cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt
     2701 tagaaccttt tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt
     2761 tgtcaaagct attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac
     2821 taataaaaat cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga
     2881 tgagtgtata ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat
     2941 ttcgcacagt ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa
     3001 caacgaataa aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt
     3061 cttctccaga aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag
     3121 cacgccgcac gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc
     3181 ttgctttttc atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg
     3241 cgcagtttgt catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt
     3301 tgcatgcata ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact
     3361 gctggaactt ttctccacat taccactgct atttctttgg agatttaact cattgatttt
     3421 tatttacagt taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat
     3481 taaaacagct gttgtattta gaagaatttt tttcaaaaaa ttaaaacata ttccttaaaa
     3541 actaattatt tcctacatat taaaatataa tacttccatt tccaataaaa atacatttat
     3601 aataggaaag ataaacagct gaaaagggag atttcaaatg aagaaaaaaa cgttcaaaaa
     3661 actattgttt ctagggggca cagctgctct tttattaagc ggtacaagtt attacctaca
     3721 tatccattct ccagaacata caatgaacac tgcacaaaaa agttcaacac aaaaaacgaa
     3781 aaagacaaaa gagaaagcag aagttttact agatgttcca ttagagagcc agtttgattc
     3841 tccttcttta gaaaatggct gtgaagtcac ttcgctttct atgcttttat ctttttatgg
     3901 ttatgaaaca actaaaaacc agttagctga gcaattggat tacgtccctg ttttcaatgc
     3961 agatgggact catggcgatc ctaatgaagg atttgttggt gatatcagtg gcggagactg
     4021 ggctatggtc gtctatgttc ccccagttgc ctcccttgct cagcaaatcg tccaaacgga
     4081 ttatcacact tttccaaaaa ccgatgctca actcgatgat atcaaaaaag cactatctaa
     4141 aggaaatcct gtctggactt ctgtgactat caattttgaa gtcccagatg aaactgattt
     4201 tatgacttgg accacaaata atggagaagt aagagtcact cctcttgttc atgcttgtgt
     4261 agtcactgga tatgacaaag aaaatattta tgtcaacgat ccctatggtg taaaaaatcg
     4321 agcagtaccg atcaacgatt tttcggcgat tttcactgca atgggtggac agatgctaac
     4381 tttggagaaa agctagtaat tcaaacaaaa atcccttata ctcaagatac caaacctttg
     4441 aagggagcgt agataatgga aaaattcaca cataaaaaaa tggatccaaa tgaaattccg
     4501 attatttttg tccgtgactg caagggaaat gttcaaggta aagtctctat taatgagtgg
     4561 aacgagcgtc gcagacctgc taccctcaat gaactggaaa tcaaattgta tcgtcaatct
     4621 cttgtttatt acgcagatca agagtacgag aaagccaccg atttattgaa atttctaatt
     4681 gctcgaacag agtatactcg ctttgaatat attgaacgtt tagcaaacat ctatcatatt
     4741 atgaatgaac ctgtcaaaga atatcagtta ttggacaccg tcttgtcagt agcagaactg
     4801 attgcccttc ctgctggatt agaaaagaaa ctagtacgcc gccttttacg agtaaagcaa
     4861 caactatccg atcaagaaaa ataacttgcg tttttttagg aaagtgctat gattattttg
     4921 ttgaataaat gggatgtagc caaactggta aggcacttga ctctgaatca agcaattgta
     4981 ggttcgaacc ctgccatccc aatttgatgt gcttgctgaa aaaatgaacc ccctgtaaaa
     5041 gaacaatctt tttgcagggg gattattgta ttatttttac tactagaatt tagtttacat
     5101 aattaaatta tgaataataa aatcgggcgt attcttaata caaaaactga tttacccaat
     5161 aattgctaat gctttctccg gaactttttc tctaggaact tcctcatacg tttctatgtg
     5221 tgctccttta ttgctaattt tcaaataatg attttctttt aacacagaaa gaccattaaa
     5281 ttcaaccgtt cgttctttcc cattggcatc agcagctttc tgcacatacc ttgctgtacc
     5341 atattcattt acttcctctg gtttttgtgt ctttacatag acctctcctt tttcaactaa
     5401 tggatttagc tgatcaagta taccagggat ttctccataa cttccttcag tataatattt
     5461 cagtccaaat agcaaaatac cactaatcgc cgccagtcca atcaaatatt taatcacttt
     5521 catctttcta cctccttgtt atatattcag tatatgggtc agttaaagaa attccatccg
     5581 tcccaagttg gagatttttc tcctacttta gaagcgagaa tcgagtgttt ttttagtaaa
     5641 aatgatcgtt atttgatatt attgacgtgt ggataaatca gtttttctcg ttttgtccat
     5701 gtaaaaaatc atgttgatag caaaggatgt gttcaaaatg aatcaagaag aattatttca
     5761 aaaagtcaag gaaatgatta agaacggcaa tttcgatggc gcaaaacgat ttatcgaaga
     5821 acataaagaa caattaggac cttataaaga gaaagcccaa aatcttttaa aagatgtaaa
     5881 tatcgacagt gtcaaaaaca aatttaaaaa tctattcaaa taagtaaaac tttcactttt
     5941 gtaaaatcaa aggaggacaa tgctgctgca tcgtcctcct ttggttcttt tctgaatact
     6001 tcatactaaa ataaacgtgt cggatcgtaa tgataagtca cattgccgtt cagtgaggct
     6061 tttcccacca catatttacg attctccaac ttcagccacg cttctcgaaa agccattaat
     6121 tcttctcttt ttacatcaat cttttcgatt tttccatcga tcaaatcttg aataagttgt
     6181 tcatatggat tcattttttt cctccatctg ctgtcaatca ataagttgta aaaataggtt
     6241 catatgcttt tttggtatct agatcttctc tgactttgac tgtcgtataa ataatttttt
     6301 ctactgggat actataataa cttccttcac cattattgaa tcggtgaacg tctttctttg
     6361 ctaaaatacc atttatttta ttcgtcagta cacgttgttc gacactgtta cttacaacat
     6421 agtaaatcac ccgaatatta ttgatcaaat gcaaatcgat ttctaacact acatgatcca
     6481 tgaaaatccc actccttctt tcactttgat tatagcaagt ttctcctcta atttcaaaat
     6541 cgatacagat tttaccggat aaatccacaa aactgcttgc gccatttcgc acaaagtgtt
     6601 attttgtatc atggacttta tttatcggag gcaatagtat gatcgcgatc ggtcaatttg
     6661 ttttttatat tccttttttt attatgataa gcattctttt ctattacata aaatggacaa
     6721 aaaagaagtt ttcagtttta ctggcctctt tacctgctgt atattttact tatcaaattt
     6781 tttcttttag gcattgggaa acaacgtctg tattaataac acacatcatc gaattgacgc
     6841 tttcagtaat ttttcttatt atttggatct attttttata taagaatcag aattgaatcc
     6901 ctcgcatgtt taaaaagaaa acgattaaag atgcagcaaa tttctgccga tctttaatcg
     6961 ttttttctat tctgttatac caaaaaaatg tttgaatcgg tgaaggatcg ttccttgttt
     7021 taattctata aattcttgtg cgatcgggta cttttcttcc aaattttctt tgttcttttc
     7081 gatcaggctt ttcgcttctt catatttttt atctgcacat agtgctttta cttcctgtaa
     7141 tacttttcct gcttccattt gcctcaccct cttgccattt tattgcttta agttttattt
     7201 aagttatacg cattattcta gtttcatccc aaataacctt ttttcatttt tactcctcga
     7261 actaatcagt tttctaaagg ctgattggtt cgtctttttt atttttcctc catttcattc
     7321 tgctcttctg ttaatttatc taatgctttg attgatgctg cggctcttgc ataatcatag
     7381 ctgtataatt ccataaattt atcaggcaga acaaaccacg ctggatgata accgttagct
     7441 gtgacaggga atcctttatc ttgttggtta tctccatccc atctcagagc aacacctttt
     7501 tttcctttcc actttactaa agcgatcgag tatcccttct ttgtttgtgt gccgtcttca
     7561 ataattgcta aaatttctat tttttctttt ggcgcacgga cttcttgagg acgaaccatt
     7621 ttctattcct cccttatctc attacttcac gaccaacaca ctgcaagggg catgtgatac
     7681 gacataagaa gcggtcgatc caactaatgc ttgttgtata gcaccttttc ctgtcgctcc
     7741 cataacgatc aaatcaatat tttcttgtcc agggatgaca ttggcaatca aatttcttgg
     7801 atctccagtt tcaactattg cgtggatctc agcaatgccg tactctttgg catcattgat
     7861 ttttttcagc atggctactt ctgttctttg tttttcatct gcatagattt ttgaaaaggc
     7921 ataggcacta tgggtcagct caactttgtt gatgattgac acgataaata agtgggcttc
     7981 attgtccttt gctaagtcaa gggcttcagc gaacgctttg atcgattgtc ttgatccgtc
     8041 aactgctacc atgatgttct ggtatctttt actcattgga accgcctcct ttttctttta
     8101 ttgtaacatc tcaagcaaaa atacaaaaaa tatacgcaat atgtaaataa aatgatgaac
     8161 aaaagcaatt tctttcaagt tatttataca tttcttttct catcagaaca cctgttctaa
     8221 tcccattatt tctgcattat gtgaaattcc tcatcatttt tcacatcgag cgaacatcat
     8281 tctgttacaa aaaacgtgga tttgtcataa attgtcatgc ttcttttacc tatgaaatat
     8341 tttcacgtgt taaagtattc ctcgttgaac acaacaaata aaacttttta acgaataaag
     8401 gagatttttc atgacatcac ttaaaacttt actttttgga acaactttgg ctgccggcgc
     8461 tgcattcttc atgggaacga ctgctcatgc ggacgaagct tataccgttc aatcaggtga
     8521 tactctatca acgatttctc aaaaatacgt tggtgataac tccttgatca atgccattgc
     8581 agaatcaaat tcaatttctg atattaacct gatctactca ggacaacaat taacaatccc
     8641 aacagaaggc tctgcacaag cagctgctga acctcaagca gccgttcaag aagcaccagt
     8701 ccaagctgaa cctgttcaag ctgaacaacc tgttgtacaa gaaacggttc aaacggaaac
     8761 acaagcagcg cctgttgctg aaacacaacc tgctcctgct gtaacagaaa ctgctgctac
     8821 tccagcaagt acaagctctg caaaagaatg gatcgcacaa aaagaatcaa gcggttctta
     8881 cacagcaacg aacggacgtt acatcggccg ttaccaatta gattcttctt acttaaatgg
     8941 tgactactct gctgcaaacc aagaaagagt agcagaacaa tatgttactt cacgttatgg
     9001 ttcttgggaa gcggcgaaag cattctggga agcaaacggt tggtactaag attcattatt
     9061 tgaacgttta aacacattca aaatatagta agaggtcatg cgatttattc tttcgcatga
     9121 cctctttttg agtttaagtt tagtctttat tccttaacta tcgtttgcca gtatttcttg
     9181 tatcagaatc tataaatcta ctatttgaat caatctatta ggttttaaac tgtcccacct
     9241 tcacacaaat tttttttgat ttatttgaat ctggttccgt tgtttaaaat ttttcctata
     9301 ttcttttaga taatatgtta ttttctttct catcgctcca ggtgtacctt ctctttataa
     9361 aaaaacaaat tatgcggcta agaagactcg aacttccacg aggtcaccct cactagcgcc
     9421 tgaagctagc gcgtctgcca attccgccat agccgcatca catcttttag tttaggatta
     9481 catgtgtttt ttgtcaagaa catatttttg ttctttttca tttctgtacg ccctccctta
     9541 tgccatctac acaaataatt catccgagca actccatcat ctattgaggg ttggtgaaaa
     9601 aatctgtttt atccatatga tcgatttcaa tgttaaacga acgactctgg gattagtaac
     9661 tattttattt ttttcttcat ttcttttttc ctctttttct cgattcagct atcttctttc
     9721 atttggatat tgattatttc ttctgttgat tactatcctt ctggaattct agacgctgaa
     9781 gtaattcacg ttttctttct tctagagatc ataagtaacg aatgaacgaa cttcaaataa
     9841 tttttttatt gtaattcata tttgtattgt tcgatgattc ttaatacgat atgacacaat
     9901 aaataaaaat aggcatggct atttacaaca atagtgctat agtagaaaac aaatgaataa
     9961 ggttacttaa agaggtgaat acgatgaaac tgatcaaact atgggaagca gatttaaaga
    10021 aagcttatca gctacaaact agctttggac caaatgagag tggatttatc aacaatgctt
    10081 atggctatac atttgctgaa tttttagatt atgtaaaaaa atgcgaaaaa acgtctttag
    10141 gaatcgatct tcctgagagt tacgttcccg caaccgtctt tattttagaa agtgatgaac
    10201 atgagtatgt aggaattttt aatttgcgcc ataaactgaa cgaaacatta agaaacggcg
    10261 ctggccatat tggttacggc atctccccta attatcgtaa aaaaggatat gccacacaag
    10321 gattagcatt agtactacaa gaggcaaaaa aaatcggcat tgatgaggca cttttgtctg
    10381 taaataaaaa aaatcttggc agtcttaaag cacaacaaaa aaatggggct gcgatttatc
    10441 gtgaagatga gaaagaatac tatacgaaaa tcaaactgat gtaaaaaaga aggattccaa
    10501 aaggaaaggg atttgaatgt cctttatcaa tagaacacat ttatttaatt aacttataat
    10561 atagcagaca aaattttata aacaaagaaa ccttttatct cttttcttct agaaaggata
    10621 aaaggctttt ttgtttttcc tatttgcttc tcatagctag tcagccaaga tttctatcgt
    10681 atccccaacg caatccgtgc ataacggctc atcttatctg tcgtccatgc tggataccag
    10741 actagtttga cttctgcttt cgttacttct ggcacttctt ttaatgcgtc atggatagat
    10801 tctgttaaaa tatctgctaa tggacagccc atagttgtta gagtcatctt aatgactgtt
    10861 tctccatttt caggattgaa ttctatatca taaatcaagc ctaaattgac gatgtcgatt
    10921 cctaattcag gatcaatcac catttccaag gcagcaagaa tacgttcttt gattagttct
    10981 atttcttgtc cagaccgttc ttggtttgct tcgctcatcg tacgacactc cttaacacga
    11041 tttttattta tcatactctt tttttagctg cttgtaaatg agaatttaga agtaagattc
    11101 tcgtttaaat ttataaaaat gttcttatta g
//
LOCUS       DAPBBR010000073        10992 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPBBR010000073 DAPBBR010000000
VERSION     DAPBBR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.076"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="RD488_002351"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="RD488_002351"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7658403.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            2714..2938
                     /locus_tag="RD488_002352"
     CDS             2714..2938
                     /locus_tag="RD488_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658404.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            3055..3552
                     /locus_tag="RD488_002353"
     CDS             3055..3552
                     /locus_tag="RD488_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7658405.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            3639..4031
                     /locus_tag="RD488_002354"
     CDS             3639..4031
                     /locus_tag="RD488_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7658406.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            4015..6462
                     /locus_tag="RD488_002355"
     CDS             4015..6462
                     /locus_tag="RD488_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7658407.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            6465..8648
                     /locus_tag="RD488_002356"
     CDS             6465..8648
                     /locus_tag="RD488_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7658408.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            8645..9646
                     /locus_tag="RD488_002357"
     CDS             8645..9646
                     /locus_tag="RD488_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7658409.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            9661..10575
                     /locus_tag="RD488_002358"
     CDS             9661..10575
                     /locus_tag="RD488_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7658410.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            10820..10936
                     /locus_tag="RD488_002359"
     CDS             10820..10936
                     /locus_tag="RD488_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDT7658411.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         3642 a         1993 c         2312 g         3045 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatatat aactggtttc tatcaaacgc
     2761 tcaatcactg gtgcttttag caatcgttgt gattggcttg tatcttggct tcaagcgtga
     2821 gtttagcaaa ctgattggct ttttaattat tgcgattatt gcggttggct tagtcttcaa
     2881 cgctgctgga gtaaaagaca ttttactaga gctattcaat cgcattattg gtgcttaaat
     2941 aaaaccgttc ttttgtggaa tataagtggt tttcttatgt tccgcaaagg aatggtacac
     3001 caaacgaagt gcggtaggga tttttgaatc tctacaaaga aaggacgtga atatatggac
     3061 gatatgcaag tctatattgc gaatttaggc aaatacaatg agggcgaatt ggtcggtgcg
     3121 tggtttacct ttcccattga ctttgaggaa gtcaaagaga aaatcggctt gaatgatgaa
     3181 tatgaggaat acgccattca tgattacgag ttacccttta cggttgacga atacacttct
     3241 attagcgaac tcaatcgcct atgggaaatg gtatcggagt tgccagaaga actacaatcg
     3301 gagctatctg ctctgctcac tcatttttca agtattgaag aactaagcga acatcaagaa
     3361 gatattatca ttcattccga ttgtgatgat atgtctgacg tggcacgcta ctacattgaa
     3421 gaaacgggtg ctttaggcga agtgccagcc agtcttcaaa actatattga ttatgaatcc
     3481 tatggtcggg atttagacct ttcgggaacg tttatctcaa ccaatcacgg gatttttgaa
     3541 atcgtctatt aaatctgtcg gtacattctt actggcagat tttcttgttt acggggtagt
     3601 caaaagacta tccccatttt tatgaaagga ttgattacat gaagaaaata cgaagctata
     3661 ccagtatctg gtctgttgag aaagtgttgt actccatcaa tgactttaga cttccgtttc
     3721 ccataacctt tacgcaaatg acatggtttg tcgtgtcact ctttgcagtt atgatacttg
     3781 gcaacttgcc ccctctttct atgatagagg gagcatttct caaatacttt gggattcctg
     3841 tggctttcac atggtttatg tctacaaaaa cctttgatgg taaaaagcct tatggatttt
     3901 tgaagtctgt cattgcttat gcactgcgac gaaagctgac ctatgcagga aaaaaagtaa
     3961 cgcttggcag aaaccagcca caagaagcca ttacagcagt taggagtgaa ttttatggca
     4021 tatccaatta aatatattga aaacaatctg gtctggaata aagatgggga atgttacgct
     4081 tactatgagc ttgttcccta caattactca tttctaagtc cggaacagaa aatacaagta
     4141 catgattctt tcagacagct tatcgcacaa aatcgtgatg gcaagattca tgctttacaa
     4201 atcagtacag aatccagcat actttctgca caagaacgtt ccaaaaatga agtcactgga
     4261 aagctcaaaa cggttgccta tgacaaaatc gaccaacaga cagacgcttt aatatccatg
     4321 attggcgaaa atcaagtgga ctaccgtttc tttatcggtt ttaagttgct tctcaacgat
     4381 caggagtttt ctatgaaaag tcttaccgtt gaagcaaaaa atgcttttac tgattttgtc
     4441 tatgatgtga accataagct gatgggcgat tttgttagta tgagtaatga tgaaatcctg
     4501 cgttttcaga agatggaaaa gcttttagaa aataaaatct cccgtcgttt caaaatccga
     4561 agattagata aggatgactt cggctatctg attgaacacc tttacggaca gacaggcact
     4621 gcctatgaag agtatgagta tcctctatca aagaaaaagc tggaacatga aacactgatt
     4681 aaaacctatg acctcattaa gcctactcgc tgtctggtgg aagaaaaaca gcgatatttg
     4741 aaaatccagc aggaagacga aaccgcctat gtagcttact ttaccatcaa cagtattgtc
     4801 ggcgaactgg acttcccgtc ctctgaaatc ttctactacc agcaacagca atttaccttt
     4861 ccgattgata cgtcaatgaa tgtggaaatt gtagcgaatc gtaaagccct atctactgtc
     4921 cgcaataaaa agaaagaact gaaagacttg gataaccacg cttggcaaag tgataatgaa
     4981 accagctcta atgtggcgga agctctggaa agtgtgaacg agctggaaac caatttagac
     5041 caaagcaagg aatctatgta taagctgtcc tatgttgtaa gggtatcagc aaatgacctt
     5101 gacgaactta aacgtcgttg taatgaagtg aaagatttct atgatgattt gagcgtgaaa
     5161 ctggtacgac cttttgggga tatgctgggc ttacatgaag aatttttacc tgccagcaaa
     5221 agatatatga atgactatat tcaatacgtg acctctgatt tcctcgctgg tttaggtttt
     5281 ggtgctactc aaatgctggg tgaaaatgag gggatttatg ttggctacag cttagatact
     5341 ggacgcaatg tctatctgaa acctgctctt gccagtcaag gggttaaggg ttcagtaacc
     5401 aatgcgttag cgtctgcctt tgtcggttcg ctgggtggtg gtaaatcctt tgcgaataac
     5461 cttatcgtct attatgcagt gctttatggg gcacaagcag tgattgtaga cccaaaagca
     5521 gaacgtggca gatggaaaga aaccttgcca gagatttccc atgaaatcaa tatcgtcaat
     5581 ctgacttctg atgagaaaaa caaaggctta cttgaccctt atgtaattat gaaaaatacc
     5641 aaagattctg aatcactggc tattgatatt ttgacattcc ttacggggat ttcctctcgt
     5701 gatggggaac gcttcccaat ccttagaaaa gccattcgtg cagtaaccaa tagtgaagtg
     5761 cgagggttga tgaaagtgat tgaagaatta cgggttgaga atacgccact aagtaccagc
     5821 atagccgacc atatcgaaag ttttacagac tatgactttg cccatctgct ttttagtgat
     5881 ggttatgtag agcagtctat cagccttgaa aaacaactga acattataca ggttgccgac
     5941 ttggtacttc ctgacaagga aacttccttt gaggaatata ccacaatgga gttactatcg
     6001 gtagcaatgc tgattgtcat tagtaccttt gcgttggact ttatccatac agaccgaagt
     6061 attttcaaga ttgtagactt agacgaagca tggagcttct tacaggtggc acaagggaaa
     6121 acactatcta tgaagctggt tcgtgctggt cgtgctatga acgctggggt atatttcgtg
     6181 acccaaaata cagatgacct cttagatgaa aaactgaaaa ataacctcgg cttaaaattt
     6241 gcctttcgtt ccactgacct taacgagatt aaaaaaaccc ttgccttttt tggtgtagac
     6301 ccagaggacg aaaacaatca gaagcgattg cgtgatttgg aaaacgggca atgccttatc
     6361 agtgatttat atggtcgtgt cggtgtgata cagttccacc ctgtatttga agaactgctc
     6421 catgcctttg ataccagacc acctgtgcga aaagaggtgt aaatgtgaaa ccatcaatat
     6481 taaacagaat aaaatcaaac tggacgctga aacgtctagg taaagtggca atgacagtgg
     6541 ctttcacact tgtgattgcc atttttcttt tagccatgct gggaacggtg gttcaagctg
     6601 cgggcttggt agatgatacg gtcaatgtgg caaatgaata cagccgatac ccacttgaaa
     6661 actatcaact ggatttttat gtggataata gctggggctg gctaccgtgg aactggtcgg
     6721 acggaattgg aaaacaagtc atgtatggac tatatgccat taccaatttt atttggacaa
     6781 tcagtcttta tgtttccaat gcgacgggtt acttagtaca ggaagcctat tccttagact
     6841 tcatttccgc tacagcagat tccattggca agaatatgca gacccttgca ggggttacgc
     6901 ctagtggact atcaacagag ggtttctatg ttggattcct tttactcttg attttggttc
     6961 ttggggttta tgttgcctat acaggactga taaagagaga aaccacaaag gcaattcatg
     7021 ccctcatgaa ttttgtgctg gtttttatcc tatcggcttc ctttattgcc tacgctcccg
     7081 actacattaa aaaaatcaat gacttttcat cagacatcag caacgctagt ttgtcactgg
     7141 gtacaaaaat tgtcatgccc cattcagata gtcaaggcaa ggacagtgtg gacttgatac
     7201 gtgacagcct attttccata caggttcagc aaccgtggct actgcttcaa tataacagtt
     7261 cagacattga aagtattggt attgaccgtg tggaaagcct gctctcaacc agtccagatt
     7321 ccaacaatgg ggaagacaga gaaaaaattg ttgcggaaga aattgaagat agaagcaata
     7381 ccaatatgac gattacaaag acgattaacc gtttaggtac agtcttcttc ctatttgtct
     7441 tcaatattgg gatttccata tttgtattcc tattaacagg aatcatgatt ttctcgcagg
     7501 tactttttat catctatgct atgtttctgc ctgtgagctt tattttaagc atgattccat
     7561 catttgatgg tatgtcaaaa cgagccataa caaagctctt taataccatt ttgacacgag
     7621 ctggaatcac attgattatt acgacagcat ttagtatttc aaccatgctc tataccttat
     7681 cggctggtta tccgttcttt ttgattgctt ttctacagat tgtgaccttt gcaggaatct
     7741 actttaagct gggcgattta atgagtatgt tttctctaca gagtaacgat tctcaaagtg
     7801 tgggaagtcg tatgatgaga aaacctcgta tgcttatgca cgctcacatg caccgtctac
     7861 agcggaaact tggacgctcc gtgactgctt taggggctgg gtctgccatt gccagtgcta
     7921 cgggtaaaaa aggacagtcg ggttcgggaa gttctgcgag tacacaagca gatcactctc
     7981 gaccaaacgg gcaggaaaaa tcaacactag gaaagcgtat cggtcaaacc atcggtacag
     8041 tagctgatac caaagacaga atggtagata ctgctggtaa tttgaaagaa caggttaagg
     8101 atttgccgac caatgcaaga tatgcagtat atcaaggaaa atctaaagtg acggataatg
     8161 tccatgattt aaccagaagt atttctcaaa ccaaagcgga taaagccagt ggacgcaaga
     8221 aacagcagga acaaagacgg aaaaccattg cggagcgtcg ctctgaaatg gaacaggtca
     8281 aacagaaaaa acagccagct tcttccgttc atgaaagacc agccactaag caagaacaat
     8341 ctcatgatgg acagacttca aggcaaacaa ctgtacaggc ttcctatagg gaatctcaac
     8401 aagccaaaca agagcgtcca acagttaagt ccgattcttc aagtttaaaa acggaacgtc
     8461 aaagtaatac agttcaagaa agaacggttc aaaagccagt aacttcaact gcaccaacag
     8521 atagagcttc acaacgttca atcacaaaag aacgtcagtc tactgttcaa agagtaccac
     8581 tacaaaatac aaaaagtaga ccaccaatca aaaccgccac cattaagaaa ggcagtaaga
     8641 aaccatgaag ctgaaaactt tagtgattgg tggttcggga ttattcttga tggtcttctc
     8701 actgcttctg tttgtcgcca ttttattttc agatgaacaa gatggcggtt tttccaacat
     8761 tcactatggc ggtgtggatg tttccgcaga agtgctggct cataagccta tggtagaaaa
     8821 agttgccaaa gaatatggaa ttgaagaata cgtcaatata cttcttgcga ttatacaggt
     8881 ggaatcgggt ggtacagcag aagatgttat gcagtcctcg gaatccctcg gtcttccacc
     8941 taattcattg agtacagaag aatccattaa gcaaggtgtg aagtatttca gtgagttatt
     9001 agccagtagc gaaaggcttg gtgtagattt agaatcggtt atccagtcct acaattatgg
     9061 tggtggtttc ttaggatatg tggctaatcg tgggaataaa tatacctttg aactggctca
     9121 aagtttctca aaagagtatt cgggtgacga aaaagtgtct taccccaatc ccatagccat
     9181 acctatcaat gggggctggc gatacaatta cgggaatatg ttttatgtgc aactggtaac
     9241 gcagtatctt gtcacaacag agtttgatga tgatacagta caagccatca tggacgaagc
     9301 tctgaaattt gaaggctgga agtatgtcta tggcggagct tccccgacta cctcttttga
     9361 ttgtagcgga ctgacacaat ggacgtatgg aaaagctgga atcaacttac cacgaacagc
     9421 acaacagcaa tatgatgtaa cccggcatat cccattattg gaagcaaaag ccggcgattt
     9481 ggttttcttt cattctacct ataacgctgg ctcttatatt actcatatcg ggatttattt
     9541 aggcgataac cgtatgtttc atgcaggcga ccctatcggt tatgccgact taacaagctc
     9601 ttactggcaa cagcatttag tgggagcagg acgaatcaaa caataagaaa ggacgattca
     9661 atgatgaaat tcggaaaaaa tcagaataca gaaaaacaga caccaaagga aaagaaacct
     9721 cgtgtctata aggtcaatcc tcgtaaaaag gttgtgattg tcctatgggt acttttagga
     9781 cttagtttca gctttgcgat attcaagcac tttacagcca ttgataccca taccattcat
     9841 gaaaccacca tcatagaaaa ggaatatgtc gatactcatc atgtggaaaa ttttgtagag
     9901 aactttgcga aagtctacta ttcatgggaa ctaaacgaca agtccattga taatcgcata
     9961 gaaaacctga aagcatatct gacagaggaa cttcaagctc tgaatgtcga tacagttcgt
    10021 aaagatattc ctgtatcgtc ttctgtaaaa ggatttcaga tatggacggt agaagcagat
    10081 ggcgacaatc aatttgatgt aacctacagt gtagaccaac tcattacaga gggggaaaat
    10141 acaaagaccg tccactctgc ttatatagtg agtgtctatg tagacagtac tggaaatatg
    10201 gtcctcatta agaatccgac cattactagc ataccaaaga aatcagacta taaaccaaaa
    10261 gctattgaaa gtgagggtac ggttgattcc attacaacca atgaaatcaa tgagttttta
    10321 acgacgttct tcaagctcta tcctacagcg acagccagtg aactttccta ctatgtgaat
    10381 gacgggatat taaaaccaat cggaaaagag tacatctttc aagaactggt aaatcctatt
    10441 tacaatcgta aggataatca agtcacggta tcgctgacag tggagtatat cgaccagcag
    10501 accaaagcaa cgcaggtatc tcaatttgat ttggtacttg aaaagaacgg gagtaattgg
    10561 aagattatag aataacaaat attggtacat tattacagct attttgtaat cacgtactct
    10621 ctttgataaa aaattggaga ttcctttaca aatatgctct tacgtgctat tatttaagta
    10681 tctatttaaa aggagttaat aaatatgcgg caaggtattc ttaaataaac tgtcaatttg
    10741 atagtgggaa caaataattg gatgtccttt tttaggaggg cttagttttt tgcacccagt
    10801 ttaagaatac ctttatcatg tgattctaaa gtatccggag aatatctgta tgctttgtat
    10861 gcctatggtt atgcataaaa atcccagtga taagagtatt tatcactggg atttttatgc
    10921 ccttttgggc ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc
    10981 tcatgttgat gc
//
LOCUS       DAPBBR010000074        10831 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPBBR010000074 DAPBBR010000000
VERSION     DAPBBR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10831
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.078"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..619
                     /locus_tag="RD488_002360"
     CDS             <1..619
                     /locus_tag="RD488_002360"
                     /inference="COORDINATES: protein motif:HMM:TIGR00350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7658412.1"
                     /translation="VDIIGYDTYDKINHAYAFGGVAMTINTIQAYLDIPIDFFVTLNM
                     QGLEQIVDSIGGITLTPTATFTQDSYSFYQGEIINLDGKASLAYSRNRHADDSGDYGR
                     QARQREIIMAIIEKGTKVTTLATKIPSLIKSLQGNMTTNLSVDDMWTIINKYSTALGN
                     IEQVQLKGEGQLLDDGIYYEMINEESLEEVQNILQKQLDYHLNID"
     gene            669..1193
                     /locus_tag="RD488_002361"
     CDS             669..1193
                     /locus_tag="RD488_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658413.1"
                     /translation="MQNDIRGKIKKSRHIKGISQSEVAKYLNISRQSISKWENDTSSP
                     DINNLTLLSSLYEISIDDLLKEKKEVKKNIKENSIEIIESKNKLIYLKNNTNRDEGLV
                     LLLISLIGCLISPLGLIIAPVVLKRNKATNTFYKGVIAASVICFTVSLFVSYGHFSNI
                     FHWGGSTNVEYIEN"
     gene            complement(1190..1654)
                     /locus_tag="RD488_002362"
     CDS             complement(1190..1654)
                     /locus_tag="RD488_002362"
                     /inference="COORDINATES: protein motif:HMM:NF037267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5626 family protein"
                     /protein_id="HDT7658414.1"
                     /translation="MRQVLLVVTLCLSFFLFEVNTVEAYVANNGVYYNLIQGGTQEFM
                     EVDEEGNPILIRVEEVPGLSLFSVNNGNYKISGSKFGMWKANYYVTVSNNQFIRAYSP
                     SAVAVTGSFTSTRLSLVSSKKASYTLEWKAGILSSNSYLDATLTDNSINITY"
     gene            2568..4109
                     /gene="istA"
                     /locus_tag="RD488_002363"
     CDS             2568..4109
                     /gene="istA"
                     /locus_tag="RD488_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDT7658415.1"
                     /translation="MFRYRRILEMHSEGISIRSIAASTGNSRQKITEVIRKAEEKGIA
                     RALSEEMTDQWLGEFLFPEKQLEANGRHLPDFDKIHKELAKPNVTLTLLHQEYAVECR
                     MSGKIPYAYRTFCDYYNAFARKHKATMRIRRKPGEIMEVDWAGSPAYVIDRDTGEKVK
                     AYVFVATLPCSQLSYAEAFLTMKSVAWITAHNHAFEYFGGSTDIIVPDNLKTGVKKNE
                     GIDVILNESYRELGEHYGSIILPARVSTPKDKPSVEGSVGVISTWIIAALRNTHCFTI
                     EDLNREIRMKLNEFNERPFTKKPGSRIRAFEEEEKFALNPLPLAPYKMSVWKKAKVQL
                     NYHVSVESMFYSVPYEYIQQNIDIRMTENLIELYFNSMRIATHKRLYGKFGQYSTVRD
                     HMPDNHKMYVDHTPESSMEWAETIGSSTVKVVQHLLDRYQNEKQALKSIMSLKSFGKK
                     YSKNEIETACSTALNLASLPSVKIIQTILKGNKQKRATSQSHIEDTNIEKHGFTRGAS
                     YFGGK"
     gene            4109..4861
                     /gene="istB"
                     /locus_tag="RD488_002364"
     CDS             4109..4861
                     /gene="istB"
                     /locus_tag="RD488_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HDT7658416.1"
                     /translation="MMLNEQTEVKLAELKLSGMLESYREQMTNKEYQSMSFEDRFNLM
                     VDLEHSRRKNNKLQRLIKSANFRNASASIEDIEYHPDRNLDKNLILKLASGTYLEEHH
                     NIILMGASGNGKTYIANAFGIQACRQYYNVKYIRLPELLDELTISKNQADGSFRKIIN
                     RYKKVQLLIIDEWLLTNLSLENSTFLLEIIESRLKTASTIFCSQFHPEGWHEKLGNPQ
                     IADAILDRIIHDSYQILVDGKVSMRERYGIRN"
     gene            complement(5044..5619)
                     /locus_tag="RD488_002365"
     CDS             complement(5044..5619)
                     /locus_tag="RD488_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658417.1"
                     /translation="MKNKFKYLFTILALLPITTSTLITPTIAKASEKQEDSVSYEIVK
                     NDLYIQFEEELAELIASNQSTVSVPDLFSTQSVLSTSSQDNSISEEQFFSLVEKYDGA
                     ELTAVVNSQDAFTTKFVNGGVNSYATSYRGLNALRSELKYNAGALKVGGTLVGTAGGL
                     LGVLLGMVTGDYLSGHCDDAAAGVSAFIQAG"
     gene            6407..6979
                     /locus_tag="RD488_002366"
     CDS             6407..6979
                     /locus_tag="RD488_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HDT7658418.1"
                     /translation="MNKAIFWDLLGTLGGDSRTLINQNFNFFKDTIPALKKAAQSHYL
                     NIIITNQSHISHGRITMAEYTDALESLINELEKNDIQITDVYTCPHARKDNCDCKKPQ
                     PTFVNEALKKYDLNPSKCFVVGDSGKNDMMLAKNAGINSVLLLTGEGIDSLTKYRHLW
                     SETKPTFIAENSLDAINKIHMYADGDSSDS"
     gene            7172..7735
                     /locus_tag="RD488_002367"
     CDS             7172..7735
                     /locus_tag="RD488_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658419.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(8014..8301)
                     /locus_tag="RD488_002368"
     CDS             complement(8014..8301)
                     /locus_tag="RD488_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7658420.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(8291..8620)
                     /locus_tag="RD488_002369"
     CDS             complement(8291..8620)
                     /locus_tag="RD488_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7658421.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            8925..9254
                     /locus_tag="RD488_002370"
     CDS             8925..9254
                     /locus_tag="RD488_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658422.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(9541..10026)
                     /gene="vanZ"
                     /locus_tag="RD488_002371"
     CDS             complement(9541..10026)
                     /gene="vanZ"
                     /locus_tag="RD488_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HDT7658423.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(10179..10778)
                     /locus_tag="RD488_002372"
                     /pseudo
     CDS             complement(10179..10778)
                     /locus_tag="RD488_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
BASE COUNT         3692 a         1893 c         1815 g         3431 t
ORIGIN      
        1 tgtcgatatt atcggttatg atacttacga caaaattaac catgcctatg cctttggtgg
       61 agtagccatg actataaata caatacaagc atacttagat atacctattg acttttttgt
      121 aacgttaaat atgcagggtc tagaacaaat tgttgattct attggaggaa taactcttac
      181 tccaactgcc acttttacac aagatagtta ttcattttat caaggcgaaa ttattaactt
      241 agatgggaag gcttccttag cgtactctcg aaatcgtcat gcagatgatt caggtgacta
      301 tgggagacaa gctcgtcaaa gggaaataat aatggcaatt atagagaaag gaactaaagt
      361 tactacacta gcaactaaga taccttcact cattaagagt cttcagggaa atatgactac
      421 taatctgtca gttgacgata tgtggactat tattaataaa tattccactg ctttaggaaa
      481 tatagagcaa gttcaattaa agggggaagg acaactactt gatgacggaa tatactatga
      541 aatgattaac gaagaatctt tagaagaagt tcagaatatc cttcaaaaac aactagatta
      601 tcacttgaat atagactaaa taatctattt cttaatatcc aataaataaa agtcattaat
      661 aggagaggat acagaatgac attaggggaa aaattaaaaa atcacggcat ataaaaggca
      721 tctctcaaag tgaagtagca aaatatttaa atatatctag acaatctatt tctaaatggg
      781 aaaatgatac tagttcccca gatataaaca acttaacttt attaagtagt ttatatgaaa
      841 tctctatcga tgatctttta aaagaaaaaa aagaagttaa aaaaaatata aaagagaata
      901 gtatagagat aatagaatct aaaaataaat taatttattt aaaaaataat acaaaccgag
      961 atgaagggtt agttttattg ctcatttcct taatcggctg tttgatttct cctcttggac
     1021 taattattgc gcctgttgtt ctgaaaagaa ataaagcaac aaacactttt tataaaggag
     1081 tgattgctgc ttcagtcatc tgttttacag taagcctgtt tgtctcctat ggacatttta
     1141 gtaatatctt tcattggggc ggctccacta acgtggaata tattgagaac taatacgtaa
     1201 tattaatgga attatctgtc agtgtagcat ctagataaga gttactagat aaaattccag
     1261 ctttccattc taatgtgtag ctagcttttt tgctggagac gagagacagt ctcgtgctag
     1321 taaaggatcc ggtcactgcg actgcagaag gggagtaggc cctaataaat tggttattcg
     1381 agactgtcac atagtaattt gccttccaca ttccaaattt agatccagat attttataat
     1441 ttccgttgtt gacggagaac agggagagcc cgggaacctc ttccacacga atcaagatag
     1501 gatttccttc ttcgtctacc tccatgaact cttgcgtgcc accttggatt aagttatagt
     1561 agactccatt atttgccaca tatgcttcta cagtgtttac ttcaaataaa aagaaagata
     1621 aacataaagt aacaaccaat aaaacttgtc tcaaaaaatc cctcctaaaa ttaatatact
     1681 catagtttaa tatatacggg tttaattagt aagagaacat tttgtgaaca ttcttatatt
     1741 gaaacggctc tctctacaaa tggacgcata tataagtgta tctgggttag taaacattca
     1801 ctgttaccaa ctctacttac taaacagata aaatatcaac gaaataaaaa aaccaaatca
     1861 actaattttt tactaataac gtagataata aaatcaaaaa gcaaatttga gcggttgcaa
     1921 ctataaagtg acctgatgta aaccataaga tgcttaatta agctatactt agatgagaca
     1981 ctatacttag gaagaactta gattagcata gcttcctaga acaaaaaaat acgagaggaa
     2041 gattctttta tgactaataa atatctatct gtatttactt ttttggttgg cttgtttttt
     2101 gttattaata gtgtagcaag ttctgatttt gatcttagta agattactct tttaactgta
     2161 ctaccaataa taataggtag tgtgttaatt cttttttctg tgacttccct ttttagacag
     2221 cgaggtaatt ccaaaaagca ttagcgaaaa agataaaagc agttttctct ttacccaaga
     2281 gagaactgct ttttatcatc tccacatttc ttgcttaatt aattacagct tcataaatac
     2341 tatcaatatg gctaataggg aaaccttcag taagggttac cctagatcct cctctagtgt
     2401 aaccagtgat tacggcatcg aaaatgtacc atctctgcaa taatttttac caggctcggc
     2461 aaagaaatgt accagtaagt gcaaagcagt gtaccacaaa tacctcttgt ataatgtagg
     2521 tgcacacctt agggtgtgac atttatttta caggaggtat ttttattatg tttcgttatc
     2581 gaaggatact tgaaatgcac agtgaaggaa ttagtattcg cagtattgca gcaagcacgg
     2641 ggaactcacg tcagaaaatt actgaggtta tccgaaaagc tgaggagaaa gggatagcga
     2701 gggcgttgtc ggaagaaatg accgatcaat ggctaggcga atttttgttt ccagaaaaac
     2761 aattagaagc caatggacgg cacctgcctg acttcgacaa gattcacaag gaattggcca
     2821 aaccaaacgt gaccttgacg cttcttcatc aggaatacgc agttgagtgt cgcatgagtg
     2881 ggaaaatccc ttacgcctat cgtacatttt gtgactatta caatgcgttc gcgcgaaagc
     2941 ataaagccac tatgcgcatc cgtcggaagc ctggtgaaat tatggaagtg gattgggctg
     3001 gatcgccagc ttatgtcatc gatcgagata cgggtgaaaa agtaaaggct tatgtctttg
     3061 tggcaacctt accgtgcagc caattgtctt atgcggaagc attcctaacg atgaaatcgg
     3121 tggcttggat tacggcacat aaccatgcat ttgaatattt tggcggttct accgacataa
     3181 ttgttcccga taatctaaaa acaggtgtaa aaaagaatga aggcatcgat gtcatcctta
     3241 atgaatcata tcgagagcta ggggaacatt acgggtccat cattttacct gcccgagttt
     3301 ctactcccaa ggataagccc agtgttgaag gcagcgtagg cgtcatctcc acttggatta
     3361 tagctgcctt acgcaatacg cattgtttta caatcgaaga tttaaatcgt gaaatcagaa
     3421 tgaaattaaa tgaattcaat gagcgaccgt tcactaagaa accaggatcc aggatcagag
     3481 ccttcgagga agaagaaaaa ttcgcactta atcctcttcc actggcacct tataagatgt
     3541 ctgtctggaa aaaagcaaag gttcaactaa actaccacgt ctcagttgaa agcatgtttt
     3601 attccgttcc atacgaatac attcaacaaa atatagatat tcgaatgaca gagaatctaa
     3661 ttgaactata ttttaattcc atgcgaatcg caacacataa acgtctgtac gggaaatttg
     3721 ggcagtattc gactgtcaga gatcatatgc cagataatca caaaatgtat gtggaccata
     3781 ccccagaatc ctcgatggaa tgggctgaaa ccatcggttc ctcaacagta aaggttgttc
     3841 aacacctctt agaccgttat caaaatgaaa aacaagcctt aaagtcgatc atgtctttga
     3901 agagctttgg taaaaagtat tctaaaaatg aaatagaaac ggcctgttca acagctttaa
     3961 atctggcttc tttgccttct gttaaaatta tccagaccat tctaaagggc aacaagcaga
     4021 agcgagcaac aagccaatca catattgaag acactaacat tgaaaagcat ggattcactc
     4081 gcggtgcgtc ctattttgga gggaaataat gatgttaaat gagcaaacag aagtaaaatt
     4141 agctgaattg aaactttcag gcatgcttga atcctatcgt gaacagatga caaataaaga
     4201 gtaccaatcc atgagtttcg aagaccgctt caacctcatg gttgatctgg agcattcccg
     4261 gcgaaaaaat aataaactac agcggttgat taaatctgca aactttagaa atgcctctgc
     4321 cagcattgag gatatcgaat accatccgga ccgtaattta gataagaacc tcattttaaa
     4381 actagccagt gggacttatt tggaagaaca ccataacatc attttgatgg gcgcttcagg
     4441 gaatgggaaa acgtatatcg ccaatgcctt cggaatacag gcatgccggc aatactacaa
     4501 cgtgaaatac atccgactcc ctgaactact agatgaatta accatctcga aaaatcaagc
     4561 agatggtagt tttcgaaaaa taatcaacag atataaaaaa gttcaattac tcatcatcga
     4621 tgaatggcta ttaaccaatc tttcgttaga aaattccacc tttctattgg aaataatcga
     4681 atcccgtctt aaaacagcat caactatttt ctgttctcaa ttccatccag aaggatggca
     4741 cgaaaagctc ggcaaccccc aaatcgctga tgccattcta gataggatca tacatgattc
     4801 ttatcaaatt ctggtagacg gtaaagtttc tatgcgtgaa cgttacggca tccgtaatta
     4861 aatgagtcat taaaataaat taagagccac tccatgattt tcatgagtgg ctcttagttg
     4921 accttgtggt cattattgtc gcttttatta tttgaaatgg taaccgcgtc gcacttactg
     4981 gtacatttct ttgcacttag tggtaaaaaa caatgctcta gtggtacatt ttcgatgccg
     5041 tattcaacca gcttgaataa aggcactaac acctgctgct gcatcatcgc aatggccaga
     5101 taaataatcc cctgtaacca tgcctaataa tactcctaac aatcccccag ctgtgccaac
     5161 taaggtacct cctactttca aagcaccagc attatacttc aactcgctac gcaatgcatt
     5221 taatcctctg taagaagtag catatgagtt aaccccacca ttcacaaatt tagttgtgaa
     5281 agcatcttgt gaattaacaa cagctgtcaa ttcagctcca tcatattttt cgactaaaga
     5341 aaaaaattgc tcttcactaa tagaattatc ttgactagaa gtagataata ctgattgtgt
     5401 agaaaataaa tcagggactg aaacagttga ttgattggaa gcaatcaatt cagctaactc
     5461 ttcttcaaac tgaatgtaaa gatcattttt tacaatttca taactaacag aatcttcctg
     5521 tttttcagaa gctttggcta ttgtaggagt aattaaggtc gatgtagtaa ttggcaataa
     5581 ggctaaaata gtaaataaat acttaaattt atttttcatt ttttatcctt ctttctattt
     5641 tttctacttt taataccaca acttgaaaaa taaaaaatct aagcaagagt aacatctctt
     5701 acgtaatgat tttgcaatag tttttcctcc tctcacaatc tattattatg tttttcgagc
     5761 tgtttcaaaa gcacttttct atttacatct gggaaactaa tcgttgcttt tataaaaaaa
     5821 gatgatagca gaaaaaattg aacttttctt tactataagg tatttataaa atcatcttca
     5881 taggtcaaag tagtagtatt aatctcaact ttgataagct ggtgtatatc aattttctct
     5941 ttaatatgta caatcattaa aaatagattt ttttactatt tatggtttca attaacaaaa
     6001 gaacctccac actaaatcac tataaattta ttatcacctt agttttttat gtgctcctag
     6061 catggaaatc ccatcaaaaa agtaaggttt gtattcaaat gtttttcgcc aacgagggta
     6121 tcttcttttt tacactcttt gctgtatcaa aatataactg aaattctaag tctcttctat
     6181 atcagtgatt atgtgattcg aaatatccat tccctcaaaa gaagttcata tagaaagtga
     6241 atagagagtg gctcctgtaa atatgatata gttaaactgg caaaataaaa tatgcttttt
     6301 caaaaagtaa tatttttgtt ttaattacga agaactactt ttaaatactg taagcacctt
     6361 ggcttgttag ttaactattc ttaaaatgag agggagacaa atatccatga ataaagctat
     6421 attttgggat ctgttaggta cgctgggagg ggatagtaga acactgatta atcaaaattt
     6481 caattttttt aaagacacaa taccggcctt aaaaaaagcg gcacaaagtc attatctaaa
     6541 tatcatcatt acgaatcaaa gtcatatttc acatggacgt attactatgg cagaatatac
     6601 tgatgcctta gagagcttaa taaatgagtt agagaaaaat gacattcaaa taacggatgt
     6661 atacacttgc cctcatgcta gaaaagacaa ttgtgattgc aagaagcctc aacctacatt
     6721 tgtcaatgaa gcattaaaaa aatacgattt aaatccaagt aagtgtttcg tagtaggcga
     6781 ttccggtaaa aacgatatga tgttggccaa aaatgctggt ataaacagtg ttttactttt
     6841 aacgggagag ggaattgata gtttaaccaa atatagacat ctgtggagtg aaacaaaacc
     6901 tacttttatt gctgaaaaca gtttagatgc tataaataaa atacatatgt atgcagatgg
     6961 agactcttct gattcatgat accagaagag tctccattta ttactaaaaa ccgtatcaaa
     7021 aacaatcgat tatgagacaa aatgaaatga cctcttttat taaataaaag aggtcatatt
     7081 ttgtatcata acttgttgca ttaactatgt atctataact cccttttatg atacaatcaa
     7141 gccagaatta aagtacgaaa ggaagaaaag catgagtgga tacatttatg gttatgcccg
     7201 agtgagtaca cgttcacaag aactaaatcg tcaattagac ttactcaatg aacaaaattg
     7261 taatgaaatc ctaactgaga aaatgacggg aaccaaagcg gttcgtcccc aactaaatcg
     7321 tttaaaagat aaaattcgtc cgggagatac ggtaattgta gaaagttttt ctcgattggg
     7381 tcgtagtaca aaggatttga ttgaccttgt tacctatttt gaagaacacc atgttaagct
     7441 ggtgagcttg aaagaaaact tcgataccag cacgcctcac ggacgcttaa tgatgactgt
     7501 cttccaagca tttagtcagt tcgaacgtga tttaattgtt gaacgtacca aagaaggttt
     7561 gaaaagtgca cgtgcgagag gtcgtaaagg tggccgtcca cgagtgaacc agaaagatgt
     7621 tgatcgagca gtaaaattgt ataaaagtca ggtttatagc gtaaaagaaa ttacggaaat
     7681 gactggtatt agcaaggcaa cactctaccg ctacttaaaa gacaataggg aataatctat
     7741 tttaatcttt aggaatctat aatatttatg ggagaattag agtgattttt ttattattac
     7801 taaaaaacaa tataaaataa cgcattttaa gccctctttg tgcataagga tgaagctttt
     7861 aatttgaaag aggcttaaaa tgcgttttaa ttttttctat ttttcataaa tatataggtt
     7921 agtggtttaa aattataggg tattacaact ctcagctgtt aaaaattatc ttttaaagtg
     7981 tcgtctatcc tctcaagttg aaacattggg ttcttaccta atctttttta attgttcata
     8041 aaaattttca tgcgttccac atagtaagat aggtatcact gcattatctt taatttcata
     8101 tgcaacgcga tatgtcgtac ctgcatactt gaatccaata gcccaaattc ctgataaatc
     8161 acccgttttt tgttctcccg aatgaggacg aactgctatc tcatcataaa ttatcgttaa
     8221 aaattgttct tttaatgttt tctcttttaa tttttttaga tactttatta cgtgtttaga
     8281 aggtagaatc tcataagcca atttctgctg ccaactcctc ttttgtcatc ggtttagaat
     8341 ttgcaacagt atcttcagca atagatttaa atgcagaagt taacgcattt tttctatttc
     8401 taaattcttt taagatctct tgtttgctat aaccttctga aagaatatca gccaaaatat
     8461 cttcactaaa atcaaaaaat tcttttttag gctctacaaa ctcataaagg ataccattct
     8521 ctacaagctt agcttctact tcaacaccat tgggcacatc gaattcttta gggaccgtta
     8581 acataataga atttccttgt tttcttgttt ttgtaatcat attatttcct ccattatttt
     8641 acatttcgta attacttagt aattacattg tacgctattt ttagtagaaa tacaaaataa
     8701 taaaactcct ttagaacaat tttcaaagga gttttatttg attaggaaat tatgtagaat
     8761 aataatatgt ttttaacttg gaatcaaaaa cgcacttgca agtaagttta cttcaataca
     8821 tgaaattgct tataatagtg tattggaatt aaggtagatt gacaaaagag tgatcaaata
     8881 ggtatacttc attcaaataa tcgtttgaat gtgaggtgag atgaatgaaa aaagtttgcc
     8941 aagtgactgt cgtacataaa gaaaaagtaa atggaataaa aaataaattg gatcaaaaag
     9001 atttttcaaa cttacttgtg ttagggaaat gtttcagcga tttttctaga attaaaattt
     9061 tctatgcttt agaaacctat aaggaaatgt gcgtctgtga tttagcagaa atacttactg
     9121 ctagtgtcgc tacaacgtca caccatttac gttttttaaa aaaacatgga atggcaaaat
     9181 cacgtcaaga tggaaaagta gtttattact ctttagcgaa tgaagacatc ctttccgcta
     9241 ttcgtgtttt ttaaagttat cagaaaatct atctatgaaa tcttagtttg ggggtaccgt
     9301 caggaaaatg cggatttaca acgttaagga aatttattaa agagaccaat tcctcagcac
     9361 taaaattgat aattgggctt tctttgttac tatagtgtta ggtaagcttt ttactttatc
     9421 accggttttc ccctcacttc acacctacgg gcgagtttcc ccacatcccg ttttccatct
     9481 aatccaattc attcaatatc tttatgtgta tgaaagatca gattgcttga tttagacatc
     9541 ttacacgtaa tttattctta aatgggtacg gtaaacgagc aataatacga gcaaaagtat
     9601 acctacaaaa ataataactc tgtctaattt tttttgattc atatgcttat tgcttaaacc
     9661 atataatttc agtccaagaa agcctccaac agtatttgta attacatctg ttatgtctgt
     9721 cgctccaata gcgaagataa attgaattat ttcaaaagta agacttaaaa ccagtacaaa
     9781 agcaaactta ggtaaaaatc cgatttcttt aaaattgaca ttcaaaagca agccaaatgg
     9841 aataaagatt ataacattat ctatcatctc tctgaaattc ccagtagcag taaatggagt
     9901 caagttaaga cttctttgat gataattaaa tactgataaa atattgtatt gtaatttgaa
     9961 taacactaac cagattagtg tcactaaata taaagctagc aatcctctag ataatatttt
    10021 tcccaatata atttcctcta attcttttgt ttaagttgta tcattagtat agcaatgtcc
    10081 tagttaacgt gggttttaaa ttaaaaagct aacgttaccc caaaagtgct agtacaataa
    10141 tgctgttcat taatttcgtt ggtttcattc cgccatcctt acctccttga attagtatgt
    10201 gttgatccgg gaaacactgt cacaattaca ccgtctatat tgtttcctga tatctcataa
    10261 cgaagattag tcggcacatg aatggtggta tttttagtaa caggataata aaagatctca
    10321 tatttttccc catttacact aacagaaatg gttttttctt cttttaggta atccatatat
    10381 tcctcgagaa cgaaattctt ttctttcata atcgcactat gtggtaaacc aacatagcga
    10441 atatgccatg gttcatattg aattcctgtt aactctgttt tgtcctctgg ataacgtaaa
    10501 atgaacccgt atttccaagc attttcttct atccactttc cttcaggggc tcgttccatt
    10561 ttcgtcaagc ttgatcctac atctagtgat aaacctgaat tatgctcact ataacctgct
    10621 ggtaaggcat actcagcccc catttcttgg taaagcacac tttgctcatc aaagtctcga
    10681 tagccactat taataataaa atgactaacg ccacccttta cagcatcatt gaccatctct
    10741 gaaaattttt gtgctatttc ttttgacata taaatattaa cccgtggtgc tagttaattt
    10801 taatatccta aagaatatct caaagttcct t
//
LOCUS       DAPBBR010000075        10823 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPBBR010000075 DAPBBR010000000
VERSION     DAPBBR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.079"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            258..1796
                     /locus_tag="RD488_002373"
     CDS             258..1796
                     /locus_tag="RD488_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDT7658424.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            1793..2758
                     /locus_tag="RD488_002374"
     CDS             1793..2758
                     /locus_tag="RD488_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658425.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            2745..4067
                     /locus_tag="RD488_002375"
     CDS             2745..4067
                     /locus_tag="RD488_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7658426.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4130..4234
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4308..5051
                     /locus_tag="RD488_002376"
     CDS             4308..5051
                     /locus_tag="RD488_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658427.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5066..6058
                     /locus_tag="RD488_002377"
     CDS             5066..6058
                     /locus_tag="RD488_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7658428.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6070..6807
                     /locus_tag="RD488_002378"
     CDS             6070..6807
                     /locus_tag="RD488_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658429.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            6797..7519
                     /locus_tag="RD488_002379"
     CDS             6797..7519
                     /locus_tag="RD488_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7658430.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7603..8226)
                     /locus_tag="RD488_002380"
     CDS             complement(7603..8226)
                     /locus_tag="RD488_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7658431.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            8621..9312
                     /locus_tag="RD488_002381"
                     /pseudo
     CDS             8621..9312
                     /locus_tag="RD488_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            9520..9810
                     /locus_tag="RD488_002382"
     CDS             9520..9810
                     /locus_tag="RD488_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658432.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         3620 a         1787 c         2272 g         3144 t
ORIGIN      
        1 aaataaaagt tgtgtgtgta aaaaagatat agctgattcc aagtgacaat ttcgtataga
       61 tttttatggt attcgtagtg aaaaaacgag aaccaaaaag ttgatccgac tttgttgctt
      121 ggattctttt tttgtcagca tatttagagg tatttttttc ttttttttgt tcgtgctgta
      181 aggttaaggc aagacaagtt agttgggaaa aaggaaagaa atgtttatac ttaaagaata
      241 acagaaagga aggtcgcatg aataatttta tacaaacatt aagtgaaaga aaaggcgagt
      301 tgctggaagc tgcatttcaa catctgtcca tttctctcat ttctttgctg attgcagcac
      361 tgattgctat tcctttagcg atttgggcag ccaatcataa aaaaatggca gaagtcttat
      421 tgcagatcac gggtgtgctc caaacgattc cttcacttgc cttattaggt ttacttatcc
      481 catttgtagg gatcggaact gttccagcat tgattgcact tgttatttac gctttgcttc
      541 cgattttcca aaacacgtat attggtctag ctgaaattga cccgtctatt gaagaagcag
      601 cggtagcatt tggtatgtcc agaatgagac gcttgctgaa agtagagctt cccatcgcat
      661 tacctgtcat tatctcaggt atccgaactg ccttagtttt aatcatcggt acggctactt
      721 tggcagcatt gatcggagca ggtggattag ggacatttat tttgttaggt attgaccgaa
      781 atacacctgt tttgacattg attggtgcga tcagttctgc cttgcttgca attatattca
      841 gcggactgat tcgctggttg cagcataaga aacctcgata ttccatcatt actttagcag
      901 cagtggtgtg tttatttggc ggcgtttctt tatatcagtc tgccttgttt aaaaatgaaa
      961 ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat cctgatccaa atgtataaag
     1021 aattgattga agacaacaca aaaacagaag ttgaattaaa accgaatttt ggcaagacga
     1081 gttttttgtt caatgcactg gatcaaggtc aaatcgatat ctatcctgag ttcacaggta
     1141 ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa aagtgctgat ttgacaaaag
     1201 aaaaaacata tgacgaagca gaagaattat tgaataagca attcgatatg acattattaa
     1261 aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa gagatctttt gcgaacgaac
     1321 atcaacttaa aaagatttcc gatttggcag ctatctctga tcagatcaaa gcgggattca
     1381 cactggaatt tattgatcgt tcagatggat ataaaggaat ccaagaagca tatggcttga
     1441 atttttcaag tgtacaaagc atggagccaa gtttgcgtta ccaagcaatc aataatggag
     1501 atgtcaatat tgtggatgcc tattccacag atagccagct caaggagtac gatctagtga
     1561 ctctagaaga tgatcgaggg ttattcccag cttatcaagg cgcaccgctg atgaaaaaag
     1621 attttgctaa agaacatcct gaaatcgtta aagcactgaa taaattaagc ggaaaaataa
     1681 cagaggatca aatgattgat atgaattacc aagtcaatgt cgaaaagaaa aagccgacag
     1741 aagtagcacg aatcttcctg aaaaatgaag gattagtaaa ggaggaagat cagtgactaa
     1801 attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga aagtatgtca tcgatgacct
     1861 aaatctggca atcaaaaaag gagaaatctt tgttttggtt ggtccttccg gtagtggaaa
     1921 aacaactact ttgaaaatga tcaatggatt atctaaacca tcagcaggag acatctactt
     1981 caaaggaaaa tcgttaaatg aatataatct gcagaaaatg cggtggaata tgggatatgt
     2041 gctgcagcaa atcgctttgt tcccgaccat gacagtcaag caaaatattg aagtcatccc
     2101 tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt gtagatgaac ttcttcaaaa
     2161 agttggctta tctcctgata tttatcgaga tcgtatgcct agagagttgt ctggaggaga
     2221 acagcaacgg atcgggatca tccgagctat tgctgcaagc ccagatgtga ttttgatgga
     2281 cgagccattt agcgcattag atccgatttc aagaaactca ttacaagaat tggttttgtc
     2341 cttacacgaa gaattgggca cgaccatcgt tttcgttacg cacaatatgg aagaagcaat
     2401 caagctaggt gatcgtattg catttatgaa ggatggagaa attatccaat gtgacacacc
     2461 agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg catttctttg atgaaccgaa
     2521 acagacgaaa gagtggcgag tagaagattt agtcgtcaat ggatatttct taaatgaaat
     2581 accagaaaat gctcgtcaac aagtttgctt tgatacgcct atgaaagaag tatattcgct
     2641 tctttcggtg tatccaagca ttgtgatagt agaaaagcaa agaagtattg ggtcgctgac
     2701 aagtaaagaa atctttgctt ttttaagtcg agaggaggaa ggaaatgaaa acatatgatg
     2761 caatcatcat cggttcaggt gtgagcggct taagtgctgc ttatggattg aaagaagcag
     2821 gtaaaacagt actagtggtc gaagaagatc tatggggcgg gacttgtcct aaccgtggat
     2881 gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg taatcgggta aaacaattga
     2941 gtggaaaagg ttttaacgag atcccaactg ccaactggga agaacttcaa aaattcaaac
     3001 gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca attagcagaa gctgaaatcg
     3061 atcatctttc aggaaccgct cgttttttgg atgattcatc tattgaagtc aacgaagaag
     3121 tcttccatgc ggattactta gttttggcaa ccgggcaaag acctacgatc ttaccagtgg
     3181 agggaaagga atacttgaaa actagtgcag actttttatc attgcctgta ctgcctaaag
     3241 aaatcatttt tatcggtggt ggttatattg cttttgagct agctacgatt gccaatgctg
     3301 cagggagcaa agtaaccatt gtccatcata atcaacggcc attaaaagaa tttgaggcgt
     3361 ctttggtaga ggaagccgtc catcaaatgg aagcatctgg cattcagttt gcttttggtg
     3421 ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg tttagtcgga aaagagacgg
     3481 aattagtagc agatatgatt ttttgtgcga ctgggagaca gccgaataca gaatctttag
     3541 cacttgagca agcgaatatc gtctttgata aacacggaat tgcagtcaat gattatctgc
     3601 aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt ttcaaggaaa accccaaaat
     3661 tgacaccagt cgccactttt gaaggaaatt atgtagctaa gcggataacg gatgcaacaa
     3721 gcgaacctat caaatatccg attataccta cgatcgtcta cgccagtcct aaacttgctg
     3781 aagtaggagt tacaaaaagt cacgcctctt cgtcagatca agtggtagag atggatctta
     3841 ccagttggtt cacctatcat cgtgtcaatg aaccagttgc taaggctgaa ttgacctttg
     3901 accagcaaaa ttatttgatt ggtgctgcag tgattagcga gcaagcagac gaattgatcg
     3961 atgatttgac actcgtcatc aatcaaaaat tgactaaaaa agagttggat agctatatca
     4021 tggggtatcc gacattggca agtgatctct cctatttatt gaaataatca gcatgataac
     4081 taaagcgctt gttgcttttt ccttcttgtg ctacacttta aaaaatgaat acctgtttct
     4141 ggggatgtcg tagacgacat gagagtaagt tgtgaactta gacccattga acctgtcagt
     4201 taatactggt gaagggagaa acatagcaga cgcttgaagc gggttactat gtcgtgccca
     4261 tttcaagcgt tttttgttat tcatattaga agaaaggagg taacaaaatg aagaaaaatc
     4321 tttatccagc agtcagtatg gcattcattt taattatttg gcagattgtt gtcatagttt
     4381 ggaaaatacc tgcctttatt ttacccggac ctgctgctgt attttctgca ttagcggcag
     4441 atgcacaagt attactttcc cattctgtca cgacattaaa tgaagcagtg cttggtttgg
     4501 taatagctag cgttctttct tttattactg ccttggcaat ggattattgg aagtttttag
     4561 aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt gccaatcatg gtgttagggc
     4621 cattacttac cctatggttt ggtttcggta tgcttccaaa agtgatcctt gttgtcttga
     4681 taagctattt tccgatcgta gtttcttttt cggatacatt gaggaaagta tcaaaagagc
     4741 aaatcatctt tttgaaaacg atgggggcag atacagggaa gatttatcga atatataaaa
     4801 taccagcggg tttatccggc ttcttttccg gtttaaaagt ggctgctact tattgtgtca
     4861 gcggagcagt cgttggagaa tggctaagcg ctcaagcagg cttagggtat tacatgatac
     4921 gcgtaaaaaa cagctaccag atcgataaag tttttgctgc gatcatttgt gtcattctat
     4981 tgagtttatt gctgaatggc gcttgttcat tattgaaaaa agggtattat cgtatgcttt
     5041 atatttttta agagaagggg atcaaatgaa aaaattatgg cttttattac cgctactgtt
     5101 gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc aaacaagaaa taaaggattt
     5161 gaaaaaagtg acacttgttt tggattatgt accgaatact aatcatactg gcatctacct
     5221 agcaaaagaa aaaggctatt ataaagaggc tggtttaaat gtccaaatca tcgaaccagg
     5281 agataattcg acaagtattg gtctagtagg tgcggacaaa gcacaatttg gtgtaagtta
     5341 tcaagaagat gtcacttatg ctcacgcaga tggacagaat ataccagtca aagcaattgc
     5401 tacagtgatc aaacataata cttctggatt cgccacccta tcagacagta acatccattc
     5461 accaaaagat tttgaaggaa aaacatatgc aggttggcaa agtccaagtg aagaagctgt
     5521 cttaaaagct gtgatggaaa aagacggcgg ggacttttca aaactgacaa tggtaggaag
     5581 caatggagaa gggccagaaa gcttaggaaa atcctcagat atccaatggt actttgaagg
     5641 ttgggatatg atcaaagcaa aagaagcggg tattgaacta aactatatcc cattgaaaga
     5701 attagatgaa cggttagatt actatactcc ggtaattatt acgaatgatc aactgatcaa
     5761 aagtgatcca gaattggtac agtcttttat ggatgccacg aaaaaaggct atcaggaagc
     5821 tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa tatgcaaaag aaaatgatcg
     5881 gacgttttta gaagaatcac aagcattctt gtcaaaaaat tatacggatg atcctgagaa
     5941 ttggggattg atggaagaaa aagtttggcg caattataca gcttttatgc aggaaaacgg
     6001 attgatcaag caagatgtac cttcgcaaga actattcact aatcagttta taaaatagga
     6061 gtgatagata tgtcaatcca aatcagccac ttgaatgtag tcattgaaaa cctgaaaata
     6121 ttagaagaca tccatttcac tatccctaaa gataccttta catcgattgt cgcgccaagc
     6181 ggagccggta agtcaacatt gctgaaaact ttaacaggag tccagcctat gacttctgga
     6241 acgatcaaag tagacgatca aaaagtaact ggtctccata cagcatttag ttatatgccg
     6301 caagaagata tgttacttcc ttggctgagc gtctatcaaa acgttacgtt atatcaaaaa
     6361 atcaatcatc taacaatcaa tgaagaacaa gtaagggatt atctggatat ctttgggtta
     6421 aacggctatg aacatttttt gccggaacaa ttatctggcg ggatgaagca gcgaacggcc
     6481 ttgttacgaa caatcatgaa tccttcttct tacttgcttc ttgatgaacc atttggagcg
     6541 ttagatgcta tgaccagagg gcagatgcaa gactggatgt tgaagctgcc taaaaaagca
     6601 aagcggacta ctttacttgt gacgcatgat atcgaagaag caatttattt atcagacagg
     6661 attcttgtgc tttccgcccg tccggcacat gtgattgctg agattcaagt gcctgaaaaa
     6721 cgacggtcac gtgaatggct actgcagcaa tcagagttga agcaaacgat ttatcagtta
     6781 ttggcaggtg aattagatgt taagtgatgc tcattgtcat ttagatggga gtcagagttt
     6841 agcactcctt cagcaggaac acacgatttt gacgatcatc aattgtgatt cgccagaaga
     6901 atggaaggaa aacagacagc ttgcagcaag taagactcaa gccttaagtt acggtatcca
     6961 tccttggaaa gcagatagct atacgtttga acaagttgag ccttttttga aaaaagcaag
     7021 gatcatcggt gaaatagggt tagataatat ttggacgaat gtaccgatga ctacacaaaa
     7081 aaaagtattt gagcgacagc ttgcttttgc agccataaat gagaaacctg ttgtactgca
     7141 cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa gcttacccta atcactattt
     7201 gatccattgg tattcttctt tggactatca acaagactat attgatttag gctgttattt
     7261 cagcattggt cttgatttga aaaagaatcc agcagtctgg caactagcta aagcagtccc
     7321 aatcgaccac ttacttattg aaacggatgg actacatgca gcagagtggg ctttaggggg
     7381 gattttttca gaaaaagatt atgtctcact gcttgaagaa cagttaaaga caatcgctga
     7441 gatcaaagag ctatcagttg aagaagttaa aaaaaatact tatcaaaact tggaacgttt
     7501 cattagatta ggtaaataaa aaagagatgt gacacaacta gtgtcgcacc tctttttggc
     7561 tttctttgta taaaagtaaa ctgtttgatt aataaatgaa tcttagtacc aaccgtttgc
     7621 ttcccagaat gctttcgccg cttcccaaga accataacgt gaagtaacat attgttctgc
     7681 tactctttct tggtttgcag cagagtagtc accatttaag taagaagaat ctaattggta
     7741 acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg cttgattctt tttgtgcgat
     7801 ccattctttt gcagagcttg tgcttgctgg agtagcagca gtttctgtta cagcaggagc
     7861 aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt tgaaccgttt cttgtacaac
     7921 aggttgttca gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg
     7981 tgcagagcct tctgttggga ttgttaattg ttgtcctgag taaatcaggt taatatcaga
     8041 aattgaattt gattctgcaa tggcattgat caaggagtta tcaccaacgt atttttgaga
     8101 aatcgttgat agagtatcac ctgattgaac ggtataagct tcgtccgcat gagcagtcgt
     8161 tcccatgaag aatgcagcgc cggcagccaa agttgttcca aaaagtaaag ttttaagtga
     8221 tgtcatgaaa aatctccttt attcgttaaa aagttttatt tgttgtgttc aacgaggaat
     8281 actttaacac gtgaaaatat ttcataggta aaagaagcat gacaatttat gacaaatccg
     8341 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
     8401 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
     8461 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
     8521 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
     8581 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
     8641 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
     8701 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
     8761 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
     8821 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
     8881 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
     8941 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
     9001 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
     9061 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
     9121 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaatc agttaacaga tacacaaaag
     9181 aaattagacg aagcaactgc tgaaaactca agcttgaaac aatatattca aaagttagaa
     9241 aaagcaaaag atgaagtgga agatacagct gataaatctc agcaaattgt tgaagaacat
     9301 ttgcgtaaat aatctttctt aacaagtaaa cctaaattag taaagaagca acagtaatct
     9361 atactgctgc ctcttttttt tagtacatgt ccttcatctt cgcaggaagt gccaatatga
     9421 ttttaagaaa ggtaatagac aaaaagtcaa aaagataaaa cagagtttct tctttacaaa
     9481 gggaatgtat gttcgtataa tggtattgag gtgaaggtta tggagaaaaa atatggaaca
     9541 gtagataaga tccgtacttt gcaagttagt gccagaccgt tgatccgttt cagtttaaat
     9601 ggggtcaatt gtttgattgc ttcccatagt ttgaacttcc tagctgaagt agacgaaggg
     9661 atgaagttag tcgttacagg ttattataat aatagaaagc aatttgttgt gagatcctat
     9721 catgtgttag ggaaacccaa aattgtggta gaatatgaga aaagtctata cccaagaaaa
     9781 aaggtccgac aagatgaaag aataaactag aaaacaagcg gctgagacaa aaatgtccta
     9841 gccgcttgtt ttggaaagat ggatgcagac gatgggattt gaacccacac gagcatacgc
     9901 tcacaagaac ctcaatctat atataactac atgtatttaa gtatttgtga tgaatcacta
     9961 aactttccaa actcatttga gggatattgc ttaaagattg aacagatcaa ttcgaagccc
    10021 tattagtatt cgctcaatgg ggggatcaga ggccataaaa agagactagt cattactagt
    10081 ctcaggtagt ggaattgtag gattttaaac gttcctggag agtaccggta tgtaactcga
    10141 agaggtgatt atcatagtcg taaaagtaaa ttgaagaagc ctcgcctttc acacgagaac
    10201 gtcctggttc gacagttaaa cctaacattt ggatttttga gacaaacgaa tctatatctt
    10261 gttcgtcaat tttaaaagca atatgattgt atgtctttgg cagtttattc gacgaattct
    10321 gcattactgc aatccatagg tccttaacta agaaaaattt ttctggatat aatgaaaatt
    10381 tttttgttga ctatcgtaga tttcttttgc atcaaataag gtatttaaca attaagtatt
    10441 taaaagataa cttttaagtt atctttaagt aatgcttaaa gctatgttat actctattag
    10501 gaaatataag aaggagtata aaaatgaaca aacataatag aaaaataacg aataacaaag
    10561 aactgatctt gttactaata gggatttggg gtatcttttt actctttaat atgtatatgc
    10621 cgactatgag agcggatgac gtagtttatg caagtagatt agatgaactt ggctatttgg
    10681 gtgcttcgat agaacattat aagacatgga gttcaagaat tattatagaa ctattcttaa
    10741 tgttcttttc taaacacttt atgctatgga aattattaaa ttctacgatt atgttaggaa
    10801 ttgtagtatt actttgcaag tat
//
LOCUS       DAPBBR010000076        10818 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPBBR010000076 DAPBBR010000000
VERSION     DAPBBR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.080"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..571
                     /locus_tag="RD488_002383"
     CDS             <1..571
                     /locus_tag="RD488_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7658433.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            575..1216
                     /locus_tag="RD488_002384"
     CDS             575..1216
                     /locus_tag="RD488_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658434.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1213..2130
                     /locus_tag="RD488_002385"
     CDS             1213..2130
                     /locus_tag="RD488_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7658435.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2127..2798
                     /locus_tag="RD488_002386"
     CDS             2127..2798
                     /locus_tag="RD488_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658436.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3339..3827)
                     /locus_tag="RD488_002387"
     CDS             complement(3339..3827)
                     /locus_tag="RD488_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HDT7658437.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4028..4294)
                     /locus_tag="RD488_002388"
     CDS             complement(4028..4294)
                     /locus_tag="RD488_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7658438.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4294..4557)
                     /locus_tag="RD488_002389"
     CDS             complement(4294..4557)
                     /locus_tag="RD488_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7658439.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5033..5218
                     /locus_tag="RD488_002390"
     CDS             5033..5218
                     /locus_tag="RD488_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7658440.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5360..7183)
                     /locus_tag="RD488_002391"
     CDS             complement(5360..7183)
                     /locus_tag="RD488_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDT7658441.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7781..10486)
                     /locus_tag="RD488_002392"
     CDS             complement(7781..10486)
                     /locus_tag="RD488_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDT7658442.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
BASE COUNT         3106 a         2240 c         2042 g         3430 t
ORIGIN      
        1 agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata caccagaaaa
       61 tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag atcgcctact
      121 acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag caatcacgat
      181 tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac gtgtagatac
      241 gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag aaacgttgaa
      301 taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg ttttttacgt
      361 aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg ggctgaaata
      421 cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg catcattagt
      481 ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg ttgcagagtc
      541 agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc atcagcacgg
      601 ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg ctttgatcat
      661 tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa aagctgccac
      721 gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt tattggcatt
      781 gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct ttatttattc
      841 attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt ggaattatcg
      901 ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg ttgaattgcc
      961 cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg tgattgcatg
     1021 ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt ttagtggact
     1081 gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa ttttagcact
     1141 attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg cacttagaga
     1201 ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc tcttcttata
     1261 cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac catttcgatc
     1321 acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg aatggttgaa
     1381 cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac tatcaaccat
     1441 caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg aacagattta
     1501 acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc taccgtgaaa
     1561 gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt tgaaaatacg
     1621 tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa agtcagcgat
     1681 ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat caatcgtaaa
     1741 ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc gatattacct
     1801 atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat tgttcttggc
     1861 tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga tgatcgtcaa
     1921 ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc tgatacgcct
     1981 catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa aatgcaggaa
     2041 ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca acgtttctta
     2101 caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat gtctttcaac
     2161 aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt atccgtcact
     2221 tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg gttgggatca
     2281 tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat atcatccaga
     2341 cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg ggagtcaatg
     2401 tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat acgtataccg
     2461 ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg atgactgcta
     2521 gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg gcaggcataa
     2581 gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc ggtgctggtg
     2641 gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg attattttag
     2701 caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta ggtattttgg
     2761 aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa aaacaaaagc
     2821 ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt aaggcaataa
     2881 tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct atttatccat
     2941 tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc gactaagttt
     3001 ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc atggaattca
     3061 taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc aattcttaca
     3121 tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt cgatgccttc
     3181 agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct tttatacaat
     3241 cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca gcttctcgcc
     3301 atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca tccgtcgcaa
     3361 ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac caattgatcg
     3421 atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg tgatgcattg
     3481 ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc cgtttgagtg
     3541 acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac gacactggta
     3601 ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc tgggaaccaa
     3661 taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc tgtttctcga
     3721 taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt cgttgccact
     3781 gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact tcttcctcct
     3841 tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc cttcaaaggt
     3901 ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt ggttttagaa
     3961 caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa ggttggctct
     4021 tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta ttttcctcat
     4081 caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg ccttcatgtg
     4141 taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc aatgtctgaa
     4201 tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa tccactttcg
     4261 cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat caatatcatc
     4321 gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta aagtacctgt
     4381 ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa tcaatacagc
     4441 attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat ttacctcttt
     4501 caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat tagccattgt
     4561 ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca aaaaaataca
     4621 ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa agaccccttt
     4681 ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg gtagccaaac
     4741 gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa gcctgtgagt
     4801 ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga ttgatatctt
     4861 gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg attttggccg
     4921 tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat tcatgttcac
     4981 tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa aaatggcact
     5041 gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt atgaagacac
     5101 atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct gtacattatt
     5161 tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt acagctaaat
     5221 aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata gagggcacct
     5281 ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag agggtctgtt
     5341 tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg acaacgatat
     5401 tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg agaatattct
     5461 gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag ttttgtttcg
     5521 ctgcattttt acttacgata tctacataac ggataattgg attttcaatc gagcgataag
     5581 aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct gcttcgattt
     5641 ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca taatcaccga
     5701 tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg actaatacaa
     5761 gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga agctgttctg
     5821 ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt ggcataatga
     5881 tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg attgcatatg
     5941 agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt ccttcttttt
     6001 tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg ccgatagagt
     6061 ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg atcgaaccta
     6121 gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct tgatacatgt
     6181 gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca gaaaaaccgg
     6241 tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa tacaaaatac
     6301 catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt tcaggaacga
     6361 tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag atcaatgcca
     6421 tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat ggtacagcat
     6481 tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct cgtaaaatca
     6541 aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc aatggcacag
     6601 cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca aggataaatg
     6661 tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga ttcagcatca
     6721 tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt gctggcaccg
     6781 ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac atgtagtcga
     6841 tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca ctgctgacga
     6901 catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat agcgttaatg
     6961 aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg gctgcagcag
     7021 acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat gataacgcat
     7081 cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca ttttcagcag
     7141 attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa actcctttac
     7201 acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat gttatagtac
     7261 gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa acagaaaaat
     7321 atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt tatgggcttt
     7381 ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt tctatccttt
     7441 ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc attcttacta
     7501 ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa gcttgcatct
     7561 gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg gtcgttctta
     7621 ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca atcagctgac
     7681 cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca tttttttctc
     7741 taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa atatggctct
     7801 catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag attgccgttc
     7861 ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc gtagcatttg
     7921 gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta aatggcaaga
     7981 acggattgat catttggaag aatttccctg agacttggat cggatagttc ccgcctccgc
     8041 cagagatcga cagtactaag atgataatag cgatcccttt accgacatta tcgaataatg
     8101 cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca aatgacacgc
     8161 tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat gtaacgatca
     8221 agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat tgttctcgtt
     8281 tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca acacttgaaa
     8341 gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta gctgaaccgt
     8401 tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta aagaagtcac
     8461 tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg acttcttgtt
     8521 cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt ggccagtcat
     8581 tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt ttttcattta
     8641 ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt tggataaaat
     8701 cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat aggtctgccc
     8761 cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta ttggcatcat
     8821 ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt gccactgcat
     8881 tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg tccgctttgc
     8941 tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga gaagtgacag
     9001 tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta ttaacaacgg
     9061 catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga acagctgtgt
     9121 tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga tttagctgat
     9181 caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc aggaactcga
     9241 ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg ttcaatacat
     9301 tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct gttcttacag
     9361 tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat gtaacatcta
     9421 cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat tttgtttggt
     9481 ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata tcttgtactt
     9541 gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt gtctcttgga
     9601 tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg atctctggga
     9661 ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc attttgtcat
     9721 tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc acgaattcat
     9781 ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg aggacttgtt
     9841 ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata tctttaactt
     9901 tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat actttcaata
     9961 aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc gaacttgctc
    10021 ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta tattcgattt
    10081 ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa tcctttggca
    10141 agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt tcttttgaat
    10201 caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact tgctccccaa
    10261 tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca gcaattggca
    10321 gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac gcatatagcg
    10381 aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg aaaatccgtt
    10441 tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt ctcccccttc
    10501 ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat cggctttttt
    10561 caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc tcttacatat
    10621 tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg aaagataatt
    10681 ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca ttttttgtct
    10741 ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt cttatttttc
    10801 gaatgacagg atgatttt
//
LOCUS       DAPBBR010000077        10783 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPBBR010000077 DAPBBR010000000
VERSION     DAPBBR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.081"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            28..3117
                     /locus_tag="RD488_002393"
     CDS             28..3117
                     /locus_tag="RD488_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7658443.1"
                     /translation="MSLFYLKEKLEARIEELGKYRFSKIVELSDWLVVEDETKKAKYP
                     PKDFSSAATFSVGDTWKGRDFYLWVKKEIEMPDVDDLYLYLNFGHTGGGYNSGFESLM
                     FINGKPYQGVDSNHKEVKIADEFRGKKVEVALKLWSGLEGGGPEQIQVHQFKQAELSQ
                     MMVPVDELFYYADAINKTVKELGQDNPIQYKLSHVLNHAINQINWIEPGSQTFYTSVA
                     KAVSELSEGIAAIPKDEMITVTAVGHTHIDVAWLWRLKHTREKAARSFSTVLRLMEEY
                     PEYIFLQTQPQLYKYIKEDYPEIYAKIKERVAEGRWEADGSMWLEADCNIPSGESLTR
                     QILHGAKFIKEEFNQDIHYLWLPDVFGYSWALPQILTKSGIDTFMTTKISWNQFNRMP
                     HDTFKWKGMDGSEVLTHFITTPEPGKENSWESNWYYTYNGELEPETVLGVYNAYRDKN
                     INDELLISYGFGDGGGGVNRDMLEKRRKLDKIPGLPKVQTGKAVDYFDRLQETFKNTD
                     EYVHTWDGELYLEYHRGTYTSQAYVKKANRQSELLLRQLEILFSLMEMKGQEAYPKVE
                     IFNMWETVLRNQFHDIIPGSSIKEVYQDHRIEMEGLFKEAQSLLAPLQSVGDSQTVCN
                     FANWQRSILAELPFLLDNQVYVDEAGEVIETYANGEVLYGLISNVPALGQKMIHVTEK
                     QEMAQIPTVAVVDSNQIETDFYLIQWNKSGQLTSVFDKELKREVLSGTGNVLQLFEDK
                     PMNFDAWDIDIYYQEKFQELAAQEIIVKPANALYQCVEFIYRFGESTIKQEMRLYPHT
                     RRIDFVTDIDWQERQQLLKAKFDVAVRATYATYDIQYGNVRRANNWNTSWEMAKFETV
                     AHQWMDMSQRDFGVSILNDSKYGCDVKDQTMRLSLLKGAIHPDPTADMGQHHFTYSLY
                     PHRGDFIEGKTIQEAWEINEKPLVLNGSIGTLPQITTTQDATIVIDTIKKAEDGNGWI
                     IRAHEYAGTDQTVDLTIEGLTWWRETDLLERNIGEVKDKQPSLTFAPYEIKTIRFGK"
     gene            3086..4453
                     /locus_tag="RD488_002394"
     CDS             3086..4453
                     /locus_tag="RD488_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDT7658444.1"
                     /translation="MKLKQFVLGNEGRALEITAEFCQKLKSNYEGTPKYKLAELGVVR
                     NGVVESAENVSAKSQNPFVFSIEVPTLKIPQQYHSGRCWLFAIVNLLNQQISQKLEIA
                     EFELSQNYLYFYDKLEKANFFYKNIIETADLELGSRELDFLLSKPQEDGGQWDMLVSL
                     IEKYGIVPSYSMPETENSRSSADMNKYLNAKLRLDAKKLRQMVAEDCSQKDIDEVTSQ
                     MLAEVYRMLAICIGAPPEKIDMKYRDDAGNYHAGLNLTPKEFANKYLLMNLKDYIPII
                     HAPSKNKVYNQTYTVAMMGNIIEGQPIKYLNVDMATLKALTIKQLKDHEAVWFGSDIG
                     QYTDRKLGIMATDIYAVDNLFDVDFTSNKQDRLEYCQSLLTHAMVISGVDLQNDQPTI
                     WKVQNSWGEEIGYKGFFMMTDAWLEEYVYQVVINKKYLTKEQLAKYQEEPVILPPWDP
                     MGSLA"
     gene            4528..5346
                     /gene="iolB"
                     /locus_tag="RD488_002395"
     CDS             4528..5346
                     /gene="iolB"
                     /locus_tag="RD488_002395"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HDT7658445.1"
                     /translation="MNLLQKPILFPVNEKVQLIQYITGENSVLEHVELSVYDVEAGGE
                     VSYHEAALESCVVVLSGQVSVAILNGETYPKLGTRTSVFDKIPTHSVYIGKNRSYKVT
                     AETKARILIAASKTDQSLPDRLIKPEDVLLESRGAYQNKRYVQTILSDQDTISDKLLV
                     VEVYTEGGNFSSYPPHKHDQNRLPEESFLEETYYHEINPPQGFVFQRIYSDDRLLDQT
                     MSCSNQDVVIVPKGYHPVGVPDGYTSYYLNIMAGPTKMWRFYDDPDHEWIKNRS"
     gene            5396..6373
                     /gene="iolC"
                     /locus_tag="RD488_002396"
     CDS             5396..6373
                     /gene="iolC"
                     /locus_tag="RD488_002396"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003573134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HDT7658446.1"
                     /translation="MKKFAITALGRACIDLNSVEINQPMEETKTFKKYVGGSPANIAI
                     GLAKLGETVGFIGKLSNDQHGRFIKDFMSKAGVDSSQMIFDQEGHKSGLAFTEIKSPS
                     ECSILMYREDVADLYLTPDEVSEEYIEASEMLLISGTALAQSPSREAALLAVEYAHKH
                     DVKVIFELDYRPYTWGSTAETAVYYTLLAQKAHIVIGTRDEFDVLENSVGGNNQQTVE
                     RLFQYTPELILIKHGVDGSFAYEKDGTITRGYAYKAQVLKTFGAGDSYAAAFLFALMQ
                     GKMIENALQYASASSALVVSRHSSSEAMPSVSEIEAVIAEQSWGEKVHA"
     gene            6366..8282
                     /gene="iolD"
                     /locus_tag="RD488_002397"
     CDS             6366..8282
                     /gene="iolD"
                     /locus_tag="RD488_002397"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HDT7658447.1"
                     /translation="MPKTLRLTTAQALVKYLNQQFLIVDDQKLPFVKGIFHIFGHGNV
                     LGLGQALSQNPGHLEIYQGKNEQGMGQAAVSFAKEKLRRQIFAVTTSVGPGAANLVTV
                     AGTALANNLPVLLLPGDTFASRQPDPVLQQVEHFHGQGITTNDALKPLSRYWDRIERP
                     EQLMSALTRAFEVLTDPVTAGPVTICLPQDVEGEAYDYPEDFFNEKVHYFDRRLATDR
                     ELSEAVKLIERSLKPVIIVGGGAKYSEAGSALKRFSEKHKIPLVETQAGKSTVVADFP
                     LNFGGVGVTGGAPANRLVKEADLVIGLGTRYTDFTTASKTAFDKDQTTFLNINVSRMQ
                     SYKMNGVSVVADAKTALLQIESELDDLYQTQYGDLLTSVTRDWQNERERLANLNYHDA
                     DFEMEIKNHFGAEKLANYAQQLTTELTQTAALIKINQSLPLDSIVVGAAGSLPGDMQR
                     LWKAKTVNSYNMEYGYSTMGYEVAGAYGAKIAHPDKEVFAFVGDGSFHMLHSELLSSI
                     QYGKKINVLLFDNSGYGCINNLQMGNGMPSFGTELTDYHEEIMTVDFAKIAEAYGAVA
                     YNVGNMSELEKSLAEIAESDRSTLIHIKVLPKTMTDGYDSWWNTGIAEVTADGSTEKV
                     LAEKEEKLAGAFQY"
     gene            8304..9458
                     /locus_tag="RD488_002398"
     CDS             8304..9458
                     /locus_tag="RD488_002398"
                     /inference="COORDINATES: protein motif:HMM:NF012678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDT7658448.1"
                     /translation="MYQLTLPQKIIYGDQAIKETGKIAGNLGLKTLIITDKLIVSLNL
                     LEGVLASLKEENLTWKIFDGVDREPTDQIVAEALAFYQQEDYDSIIAVGGGSCIDTAK
                     AVAVLINNSGSYAEFASGQLIAQNPLPLIAIPTTAGTGSEVTDVTVITDTQKDIKYMM
                     KQAAFLSYAAIVDPQMSRTSPASVTAATGLDALCHALESYISKKAQPITRLFSLSAIK
                     LIMENLPIAYSEPENLIARENLAQAAMEAGIAFSNASVTLIHGMSRPVGALYHIPHGI
                     SNAILLEAVIDYTKPVIISELAGIAKYLNPEKEGTDQELAECFFQELQDLIEKLAVPN
                     YASFGIEKAAFIASLDKMANDAIASGSPNNNPLVPTIEEIKMIYLASWQE"
     gene            9481..9912
                     /locus_tag="RD488_002399"
     CDS             9481..9912
                     /locus_tag="RD488_002399"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658449.1"
                     /translation="MEIKTDLNSEDSSQLAEFLLMVLDQQQEHFFPDYQTIDKSVALA
                     AYSGTELVGGLLGKISDQSLNVSLLAIDPKHQKDGLGSQLIEEVEKIAAKNQVINLLL
                     STRSYQALAFYQKNNFEIYGELKDMPFRGVDTYYLVKRLMA"
     gene            9950..>10783
                     /locus_tag="RD488_002400"
     CDS             9950..>10783
                     /locus_tag="RD488_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HDT7658450.1"
                     /translation="MTYKEIPVSVQQFMEKITTLCGNDHPQWAANINAAFANTLLTTV
                     KRHEDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKDNPDLADMISGLVKKQFFYINLD
                     PYANAFNEEANNAGHQDDETQMNPWVWERKYEIDSLCYPIQLAYLLYQNTGRTDQFSE
                     DFIRGIEKVLTVFETEQNHQDSPYTFQRFDDRPEDTLVNHGRETTVAPTGMTWSGFRP
                     SDDACHYGYLVPSNMFAVVILDYLVEIFQDILKETTLIDRIIKLKKRSMMVSKNLVRF
                     LI"
BASE COUNT         3391 a         1886 c         2441 g         3065 t
ORIGIN      
        1 aaaatgaaaa gggtggagga atagttcatg agtttgtttt acttgaaaga aaaattagaa
       61 gcaagaatcg aagagttagg aaaatatcgc ttttcaaaaa tagtagagtt gtctgattgg
      121 cttgttgtag aagatgagac caaaaaagca aaatatccac ccaaagattt ttcaagtgct
      181 gctacttttt cagtagggga tacttggaaa ggccgcgatt tttatttgtg ggttaaaaaa
      241 gaaatcgaga tgccagatgt tgacgattta tatttgtatt tgaattttgg tcataccggt
      301 ggtggttaca actccggctt tgaatcattg atgttcatta atggaaaacc ctatcaaggc
      361 gtggattcca atcataagga agttaaaatc gccgatgaat tccgtggtaa aaaagtcgag
      421 gtagcattga agctttggtc aggtttggaa ggtggcggac cggaacaaat ccaagtccat
      481 caatttaagc aagcggagct atctcaaatg atggtgccag ttgatgaact attttattac
      541 gctgatgcta tcaataagac cgtgaaagaa ttaggtcaag ataacccgat tcaatacaag
      601 ttgtcccatg ttttaaatca tgctatcaac cagattaatt ggatcgaacc tggaagccaa
      661 acattttata cttcggtagc gaaggctgta tccgaattat cagaggggat tgccgcaatc
      721 cctaaagatg aaatgatcac tgtgacagca gtcgggcata cccatattga cgtagcgtgg
      781 ttatggcgat taaaacatac ccgcgaaaaa gctgcccgta gcttctcaac tgttttacgt
      841 ttgatggagg agtatccgga gtatattttc ttacaaacac aaccgcaatt atacaaatat
      901 atcaaagaag actatccaga aatttatgca aaaatcaaag aacgagtagc tgaaggtcgt
      961 tgggaagcgg atggaagcat gtggttggag gcggattgta acattccttc tggtgaatct
     1021 ttgacccgcc agattttaca tggtgcgaaa tttattaaag aagaattcaa tcaagacatt
     1081 cactatttgt ggttgccgga cgtttttggc tattcttggg cattgcctca gattttgact
     1141 aaaagtggca ttgatacttt tatgacgaca aagattagtt ggaatcagtt taatcggatg
     1201 cctcatgata ccttcaaatg gaaagggatg gatggctcag aagtcttgac ccattttatt
     1261 accacgccag aaccaggcaa agagaattca tgggaatcca attggtacta tacctataat
     1321 ggtgagttag aacctgaaac tgttttaggc gtttacaatg cttatcgaga taaaaacatt
     1381 aatgatgagt tgttgatttc ttatggattt ggcgatggcg gaggcggcgt taatcgtgat
     1441 atgttggaaa aacggcggaa attagacaaa attcctggct taccgaaagt tcaaaccggt
     1501 aaagcagtgg attacttcga tcggctgcaa gagaccttta aaaatactga tgaatatgtt
     1561 catacctggg atggcgaatt gtatttagaa tatcatcgag gcacctatac ctctcaagct
     1621 tatgtcaaaa aagcgaaccg ccaaagtgaa ttattgttgc gccagttaga aatcctcttt
     1681 tcattaatgg aaatgaaggg acaagaggcc tatcccaaag ttgaaatctt taatatgtgg
     1741 gaaacggttt tgcgtaatca attccacgat attatcccgg gatcttcaat taaagaggtt
     1801 tatcaagatc atcggattga aatggaagga ctttttaaag aagcccaaag tttattagca
     1861 ccattgcagt cagtaggtga cagccaaaca gtttgtaact ttgcaaactg gcagcgttca
     1921 attttagctg aattaccatt tcttttggat aatcaggttt atgttgatga agctggtgag
     1981 gtaattgaaa catacgctaa tggtgaagtg ctttatggat taatttcaaa tgttccagct
     2041 cttggtcaaa aaatgattca tgtcactgag aagcaggaaa tggcgcagat tcctacagta
     2101 gctgttgtgg attcaaatca aattgagaca gacttttatt tgatccagtg gaataaaagc
     2161 ggacaattga cttcggtatt cgataaggag ttaaaacgag aagttttaag cggaaccggg
     2221 aatgtcctgc aattatttga agataaaccg atgaattttg atgcttggga tatcgatatt
     2281 tattatcaag aaaaattcca agaactagca gcacaagaaa ttatcgtcaa acccgctaat
     2341 gctttatatc aatgtgtcga atttatttat cgttttggtg aatcaaccat taaacaagag
     2401 atgagattat atcctcatac tcgtcgcatt gattttgtga cagatattga ttggcaagag
     2461 cggcaacagc tgctaaaagc taaattcgat gttgctgtca gagcaactta cgcaacttat
     2521 gatattcagt acgggaatgt tcgtcgtgcc aataactgga atacgagctg ggaaatggct
     2581 aaattcgaga ctgtcgccca tcagtggatg gatatgtcac aacgtgattt tggggtcagc
     2641 atcttaaatg attccaaata tggttgcgac gttaaggacc aaacaatgcg tttgagtttg
     2701 ttgaaaggag caattcatcc tgatccaacg gcggatatgg gccaacacca ttttacctac
     2761 agtctgtatc cacatcgtgg cgactttatt gaaggaaaga ccattcaaga agcttgggaa
     2821 atcaatgaaa aaccgcttgt tttaaatggt agtattggca ctttaccgca aattaccaca
     2881 actcaggatg cgactatcgt aattgatacg attaaaaaag ccgaagatgg taatggttgg
     2941 attatccggg cccatgaata tgccgggact gatcagacgg ttgacctgac aattgaaggt
     3001 ttaacttggt ggcgtgagac ggacctgttg gaaagaaata ttggcgaagt aaaagataaa
     3061 caaccgagtt tgacatttgc accatatgaa attaaaacaa ttcgttttgg gaaatgaggg
     3121 aagagcattg gaaataactg cagaattttg tcaaaagtta aaaagtaact acgaaggaac
     3181 ccccaaatat aaactagcag aattaggtgt tgttcgaaat ggtgttgttg aatcggcaga
     3241 aaatgtctca gctaaaagtc agaatccctt tgtgttttca atcgaagtac cgaccttaaa
     3301 aattcctcag caatatcatt cgggacgctg ttggctgttt gcgattgtca atttactgaa
     3361 tcagcaaatc agtcagaagt tggaaatcgc tgaatttgaa ctttcgcaaa attatctata
     3421 tttttatgac aagttagaga aagccaactt tttctataag aatattattg agacggctga
     3481 tttagagttg ggcagtcgtg aattagattt tctactatct aagccccaag aggatggtgg
     3541 tcaatgggac atgctagttt cattgattga aaagtatggg attgttccat cttattcgat
     3601 gccggaaacc gaaaatagtc gcagttcagc tgacatgaac aagtatctaa atgccaagtt
     3661 gcgacttgat gcaaaaaaac tgcgtcaaat ggtggctgag gattgttcac aaaaagacat
     3721 tgatgaagtg acttcccaaa tgctcgcgga agtttaccga atgttggcaa tctgtatcgg
     3781 ggctccgccg gaaaagattg atatgaagta tcgtgatgat gctggaaatt atcacgctgg
     3841 attaaatcta acaccaaaag aatttgccaa taagtatttg ttaatgaatt taaaggatta
     3901 tattccgatc attcatgcac cttccaaaaa caaagtgtac aaccagacct acacagtagc
     3961 gatgatggga aatattatcg aaggacaacc gattaaatat cttaatgtag atatggcaac
     4021 gttaaaagca ttgacaatca agcaactgaa agatcatgaa gccgtctggt ttggtagtga
     4081 tatcggccaa tatactgacc gaaagctagg gattatggcc acagacatct atgctgttga
     4141 taatttattc gatgtcgatt ttacttcaaa taaacaggac cgtttagaat actgtcaaag
     4201 tcttttgact catgccatgg taatcagcgg agtagatttg caaaatgatc agccgacgat
     4261 ttggaaagtc cagaatagct ggggcgaaga aatcggttat aaaggctttt tcatgatgac
     4321 cgatgcttgg ctagaggaat atgtctatca ggtggtgatt aacaaaaaat atttaacaaa
     4381 agagcaactg gcaaagtatc aagaggaacc agttatttta ccaccctggg atccgatggg
     4441 ttctttagca taataaaaaa accgcggcta gtcataacga gatgattgtt tgtgaccggc
     4501 ccccgatttt agtaaagagg gaaaataatg aatcttttac aaaaaccaat tttatttcca
     4561 gtgaacgaaa aagttcagtt gattcaatat ataaccggag agaatagcgt ccttgagcat
     4621 gttgaattaa gtgtttacga tgtcgaagct ggcggtgagg ttagttacca tgaagctgct
     4681 cttgaaagtt gcgttgttgt tctttccggc caagtgtccg tagcgatttt aaatggagaa
     4741 acctacccta agcttggaac gagaacttca gtttttgata aaataccgac tcacagtgtt
     4801 tatattggta aaaatcgttc atacaaagtt acggcagaaa cgaaagcgcg tattttgatt
     4861 gctgcttcta aaacggatca aagtctacca gatagattga tcaagcctga ggatgtctta
     4921 ttggaatcac ggggtgctta ccaaaataaa cgctatgtgc agacgatctt gtctgatcaa
     4981 gatacaatca gcgataaact tttagtcgtg gaagtttaca cagaaggtgg taatttttct
     5041 agctatccac ctcataaaca cgatcaaaac cgcctaccgg aagagtcttt cttagaagaa
     5101 acttattatc atgaaatcaa tccaccacaa gggtttgttt ttcaacggat ttattccgat
     5161 gatcgtcttt tagatcaaac catgtcctgt tccaatcaag acgtggtaat cgttccaaaa
     5221 ggctatcatc ctgttggcgt accagatggg tacacttctt attatctaaa tatcatggcc
     5281 ggtccaacga aaatgtggcg tttctatgat gatcctgatc acgaatggat caagaaccga
     5341 tcgtaagagt ttttcagaaa aataaaacgt gtcatgagag aggaagaaaa ttaaaatgaa
     5401 gaaatttgct attacagctt tagggagagc ctgtattgat ttgaactcag tagaaattaa
     5461 ccaaccaatg gaagaaacaa aaacatttaa aaaatatgtt gggggatctc cggcaaatat
     5521 tgcgattggt ttggccaagt taggggaaac agtaggtttc atcggaaaac tttctaatga
     5581 tcagcacggt cgatttatta aagacttcat gtcaaaagcg ggtgttgatt caagtcagat
     5641 gatttttgat caggaaggac ataaatccgg actggctttt accgaaatta agagtccatc
     5701 agaatgcagt attttgatgt atcgtgaaga tgtggctgac ttatatctaa cccctgatga
     5761 agtttcggaa gagtacattg aagccagcga aatgctattg atttcaggaa cagctttagc
     5821 ccaaagtccg tcaagagaag cagcgttatt ggcggtggaa tatgcccaca aacatgatgt
     5881 aaaagtgatt tttgaattgg attatcgtcc ttatacgtgg ggatcaactg ctgaaacagc
     5941 cgtttactac actttgctag cacaaaaagc ccacattgtg attggtaccc gcgatgaatt
     6001 tgatgtgtta gaaaatagtg ttgggggtaa caaccaacaa actgttgaaa gacttttcca
     6061 atatacgcct gaactgatcc tgattaaaca cggggtcgat ggctcatttg cttatgaaaa
     6121 agatggcacg attacgcgag gatatgccta taaagcacag gttttgaaaa cctttggggc
     6181 aggtgattct tatgcggccg ctttcttgtt tgctttgatg caaggaaaaa tgattgagaa
     6241 tgctttacag tacgctagtg cctcgtcagc gctagtagtt agtcgtcata gttcttcgga
     6301 agctatgcca agtgtgtccg aaattgaggc agtcattgca gaacaaagct ggggggagaa
     6361 agttcatgcc taaaacgcta cgcttaacca cggcccaggc attggttaag tatttgaatc
     6421 aacagttttt gattgtagac gatcaaaagc taccctttgt gaaaggtatt ttccatatct
     6481 ttggccacgg aaatgtctta ggattgggac aagctttgtc acaaaatcct ggtcatttgg
     6541 aaatctatca aggaaaaaat gaacagggaa tgggccaggc ggctgtttcc tttgcaaaag
     6601 aaaaactgcg ccgtcaaatt tttgcagtaa cgacttcagt gggaccgggt gctgcgaatc
     6661 ttgttacagt agctggcact gccttggcta ataatttgcc agtattatta ttgccgggag
     6721 atacttttgc aagccgtcaa ccagatccag tcctgcagca agtcgaacat tttcacggtc
     6781 aaggaatcac gacaaatgat gcattgaagc cactttctcg ttattgggat cggattgagc
     6841 gcccagaaca attgatgagc gcattaaccc gggcgtttga agttttgact gatcctgtga
     6901 ccgcgggtcc cgttacaatt tgcttacccc aagatgtcga aggggaggct tacgattacc
     6961 cagaggattt tttcaatgaa aaagttcatt attttgatcg ccgcctagct acagatcgtg
     7021 aattatcaga ggcggttaag ttaattgaaa gaagtctgaa accagtgatt atcgtgggtg
     7081 gcggggcgaa gtattcagaa gccggatcag ctcttaaacg tttttcggaa aagcataaga
     7141 ttcctttagt ggaaacccag gcaggaaaat caacggtggt tgctgatttt ccattgaatt
     7201 ttggtggtgt cggtgtgacc ggtggtgcac ctgccaatcg tcttgtgaaa gaagctgatc
     7261 tagtgattgg gttgggaaca cgctacaccg attttacgac agcctcaaaa acggcttttg
     7321 ataaggatca aacgactttt ttaaatatca atgtttcgcg gatgcaaagc tacaaaatga
     7381 acggtgtttc agtggtagct gatgccaaaa cggccctatt gcaaattgaa tctgagcttg
     7441 atgatttata tcaaacgcaa tatggtgacc tgttaactag tgttactagg gattggcaga
     7501 atgaacggga gcgtctggca aatttgaact accatgatgc tgattttgag atggagatca
     7561 aaaatcattt tggcgcagaa aagttagcca attatgcgca acaactaaca acagaattga
     7621 ctcaaaccgc ggctttaatc aaaatcaatc aaagtttgcc gctggatagt atcgtggttg
     7681 gggcggctgg ctctttgccc ggtgatatgc aacgtctgtg gaaagcgaag acagttaact
     7741 cttataatat ggagtatggc tattctacga tgggatatga ggtagcgggt gcttatggtg
     7801 ccaagattgc gcatccagat aaagaagttt ttgcttttgt tggagatggt agttttcata
     7861 tgttgcattc ggagctactt tccagtattc aatatgggaa aaaaatcaat gtcttacttt
     7921 ttgataactc aggctatgga tgtattaata atttacaaat gggcaatggg atgccatctt
     7981 ttggaacgga actgacagat tatcatgagg agatcatgac ggttgatttt gcaaaaatag
     8041 ccgaagctta tggggcggtt gcttataatg tcggtaatat gtctgaactt gagaaatctc
     8101 tagctgaaat agctgagtct gaccggagta cattaatcca tattaaagtt ttacctaaaa
     8161 ctatgacgga tggatacgat tcatggtgga ataccgggat tgctgaagtt actgcagatg
     8221 gttctactga aaaagtttta gctgaaaaag aagaaaaact agcaggggcc tttcaatact
     8281 gagaagccca gaaaggtgtc aaaatgtatc aactaacttt gccgcaaaaa atcatttacg
     8341 gcgatcaagc aatcaaggaa acaggaaaaa tcgctggtaa ccttggtttg aaaactttga
     8401 ttattacaga taaactaatc gtctctttga accttttgga aggtgtgctt gccagcctaa
     8461 aagaggaaaa tctgacctgg aaaatttttg atggcgttga ccgcgagcca acggaccaga
     8521 ttgtagctga agcattagct ttttaccaac aggaagatta tgattcgatt attgcggtgg
     8581 gcggtggcag ctgtatcgac actgctaaag ctgtggctgt gttaatcaat aatagtgggt
     8641 cctatgctga atttgctagt ggccaactga ttgcccaaaa tccactgcct ctaattgcaa
     8701 tacctacgac tgccgggact ggctccgaag tgacagatgt gaccgtaatc acagatacgc
     8761 aaaaagatat taaatatatg atgaaacagg ctgctttttt atcctatgca gcgattgttg
     8821 atccacaaat gagtcgtaca agtccagcat cagttacagc agcaaccgga ctagatgcat
     8881 tatgtcatgc tttagaaagt tatatttcta aaaaagccca gcctattaca aggctctttt
     8941 cactttcagc aataaagttg attatggaaa atttaccgat tgcctatagc gagccggaaa
     9001 acttaatagc ccgtgaaaac ttggcgcagg cagcaatgga agcgggaatt gccttttcaa
     9061 atgcttcggt taccttgatt catgggatgt caagacctgt tggcgctctg tatcatatcc
     9121 ctcatggcat ttccaatgcg attttattag aggcggtgat tgattacaca aaacctgtaa
     9181 tcatctcgga gttggctggt attgcgaaat atcttaatcc tgaaaaagaa ggtacggatc
     9241 aggagttggc agagtgcttc tttcaagaat tgcaggactt gattgagaaa ttagctgttc
     9301 ccaattacgc aagttttggt attgaaaagg cagcttttat tgcatctttg gataaaatgg
     9361 caaatgatgc aattgccagt ggtagcccca ataacaatcc tttggtacca acaattgagg
     9421 aaataaaaat gatttattta gctagttggc aagaatagtc aaagaaaagt aggtagaaaa
     9481 atggagataa aaacagatct taattcggaa gattctagtc agttggctga gtttctttta
     9541 atggtcttgg atcaacagca ggaacatttt ttccctgatt atcaaacaat cgataaatct
     9601 gtggccttgg ctgcttattc aggaactgaa ttggtaggcg gtctgctagg gaaaatcagc
     9661 gatcaaagct tgaacgtttc gttattagcc attgacccga aacatcaaaa ggatggtcta
     9721 ggaagtcagt tgatcgaaga agtcgaaaaa attgcggcaa aaaaccaagt cattaatctt
     9781 ctactttcga cgagaagtta tcaagcgctg gcgttttacc aaaaaaataa ttttgaaatc
     9841 tatggcgaac tcaaagacat gccgtttcgt ggcgttgata cgtattactt agtcaaacgt
     9901 ttgatggcat aacgtttaaa gttccaataa agaataaaga ggcacaaaaa tgacctacaa
     9961 agaaatacca gtctctgttc aacaatttat ggaaaaaatc acgactcttt gtggtaatga
    10021 ccacccacaa tgggcagcaa acattaatgc tgcctttgcc aatactcttt taacaacggt
    10081 taagcgacat gaagatggca caactttttt gttgactggc gatattcccg caatgtggtt
    10141 gcgggattca actgcccaag ttcggcctta tttagtcatc gccaaagata atccagattt
    10201 ggcggatatg attagtggtt tagtaaaaaa acaattcttc tatattaact tggatcctta
    10261 tgcaaatgct tttaatgaag aggccaacaa tgcggggcat caggatgacg aaacacaaat
    10321 gaatccttgg gtctgggaac gaaagtatga aattgattct ctttgctatc caatccagct
    10381 ggcttatttg ttatatcaga atactggccg tacagatcaa tttagtgaag actttattag
    10441 ggggatcgag aaggtcctga cggtttttga aacggaacag aaccatcaag actcacccta
    10501 cacttttcaa cggtttgatg atcgaccgga agatacgtta gtcaatcacg gacgggaaac
    10561 gacagttgca ccaacgggta tgacttggtc aggttttcgt ccaagtgatg atgcttgcca
    10621 ttatggttat cttgttccgt caaatatgtt tgcggtggtc atccttgatt atttagtaga
    10681 gattttccaa gatattttga aggagacgac actgattgac cgtattatca agttaaaaaa
    10741 gcgatcaatg atggtatcca aaaatttggt aagattttta ata
//
LOCUS       DAPBBR010000078        10757 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPBBR010000078 DAPBBR010000000
VERSION     DAPBBR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.082"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            101..1048
                     /locus_tag="RD488_002401"
     CDS             101..1048
                     /locus_tag="RD488_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003729435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7658451.1"
                     /translation="MKQDSYSVKDANVILSKLILGSSDYLKLDNKDKVDRMFTRYVEE
                     GGRTFDTARHYRESEAVIGSWLKDKKREDYTIITKGCHPVREAPDTPRVNPESILADL
                     TTSLEMLATDYVDVLLLHRDDPSQPVGPLMETLSQLVDEKKIRSFGVSNWELPRIIEA
                     KKYCEDNGLNPLSFNSPNFSLAKVNEPRWENCVTADDLMIAWHEETDFPLISWSAQAE
                     AFFGNRFSPDDVNDPEMAEFVAVYFNDLNWKRLVICEELAKEKGVKPIQISLAYVLSQ
                     TFPSYATIGPEEEWQLLDSVEAMNIQLSAEEIMRLKKGE"
     gene            1054..1818
                     /locus_tag="RD488_002402"
     CDS             1054..1818
                     /locus_tag="RD488_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003771105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7658452.1"
                     /translation="MDKTKIAAQMYSVRKELEKDPENTFKSLKEIGFEAVQLDGMRGH
                     KETEIKALVDKYGFKIAGMHIKHDRFFNDRDGIISESLLFGCKTIYDKYIDDEEQHTK
                     GYIQTKQQLVTTQATLGKLGFRIGLHCPEYDFNQTVEGRTILDYITDPVFGTAVYAEP
                     DTYWISVAGKDPLEEFRKFSGRAPIVHLKDYIKGFAPEDMDNNLTELGNGDVDFKAIV
                     EWGEKSGVEYYCIEQDYSKIGIFNSLAKSFDHLMSI"
     gene            1835..3088
                     /locus_tag="RD488_002403"
     CDS             1835..3088
                     /locus_tag="RD488_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7658453.1"
                     /translation="MKKNSRIVMMGVALVSGLVLAGCGNGSASNSDKVELSINYYNGA
                     ISKKTMDNAKKEFSDYKLSFKQIPANDDFDTKLKASLNSKSAPDITAINSNISDYLPY
                     ADKFVNLLDYDSETLAADFVEWKWDSCFTNDKKTQIAMPIDIGPTALFYNVDAFAKAG
                     LPTNDQEISKALKDEESLMAAAKQMKEKADMPFFQSSLSLLQSKNRTMTEHIYDENGK
                     LTYANGQLKEIWDYAVKAEKSGYTLGTKGNSADGANSVQKGMFGGMIEASWGINDLAE
                     NGVSPKQWMIAKSPFTASNYGGSYLAVIKTSSHPKEAAEVVKYLTNEDSQRANYEELA
                     LFPSNTKVYDDSFKAAKNELFGDEEFNHYFIDAANELEYVPSDPRESAAFKCFEDQII
                     LVAEQGKDPEKAWNDAVKKVEEMSK"
     gene            3171..4094
                     /locus_tag="RD488_002404"
     CDS             3171..4094
                     /locus_tag="RD488_002404"
                     /inference="COORDINATES: protein motif:HMM:NF012738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7658454.1"
                     /translation="MEIGEMMNSESKSKKKFSFDKVAPYVFVSPFYILFLIFGLFPVI
                     FSGVLAFSKWDGLGDIQFVGLDNFTRLLRDADFYLSVKNTLIIWAVGTFPMLFLALIL
                     AFLVNLKFIKHKELLKSIFFLPNITSVVAVTILFGLIFSNLDGLANALLQFLGFEPIK
                     WVTSPFWVRIVIALINIWMYLGYNMIIYLTGITKIPNDYYEAAVIDGATNMQIFWNIT
                     IPQLKPIILFTVMMSTIGGLQVFSEAQVLVPQGATPEGGAMTIVYYLYNTAFTNNEYG
                     YGSAVAWALVLIILVFSLINWYLTTYRIKGE"
     gene            4097..4921
                     /locus_tag="RD488_002405"
     CDS             4097..4921
                     /locus_tag="RD488_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7658455.1"
                     /translation="MSNRIFKILVRAFLAIGVFLSIFPFYWMIVMASKDNSEIYHIPP
                     DLMLGSELMNNIKTVFTETTFFSSLLNTLFVALTSTLLILFFDSLAGFSFAKLNFKRK
                     AFLFTFLLGTMMIPGQLNIIPSFYLMDKFGWVGSYKALIIPGMANAFGIFWIKQYCTD
                     AIPDSLLESAKLDGCTLFKAYYKVVLPIMKPALAFLALYSFMGAWNDYMWPLIILNDE
                     SKYTLMLALTQLQGLYKTNYPLVITGTLLATLPLLLVFTIFSKQLISGITEGAVKQ"
     gene            complement(5034..5321)
                     /locus_tag="RD488_002406"
     CDS             complement(5034..5321)
                     /locus_tag="RD488_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7658456.1"
                     /translation="MKEKNPYYRLKYVRIYKRRGKKRAIITIARMMLTAIYHMLSTGE
                     VWNPTDLYKIDMPDNLVQKQKDKAIKQATKLLISEGLLPDDFVRKDLEPAI"
     gene            5657..6247
                     /locus_tag="RD488_002407"
     CDS             5657..6247
                     /locus_tag="RD488_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658457.1"
                     /translation="MEVNMKEKFIALQAKLMDLILLSGLILIGAMTIIGFFYGIVAAF
                     VYLETKSEDKWQVLKKRQTILISLLLEMSAVFVAGIFFLNARLLSQLQGGATIIISFF
                     LAVCTLILIPLYFILLHKLAVGTIFTKETFLNSVKVILIGFPTWFTQIILMIALSVLT
                     YLFPALSIITVGYLITRTNKIINVQKMKLASLQEVY"
     gene            6247..8256
                     /locus_tag="RD488_002408"
     CDS             6247..8256
                     /locus_tag="RD488_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7658458.1"
                     /translation="MKLSQREIDLLKLALDGEEETTVPQLKKQLKLSVHQIRYAIDKV
                     NRFLIEKKLNQIFIEKDRLVIEQRRKIKKEIDFFISHSTPEQFKFTAEQIEYFISLKL
                     LLSDQRLPINYFVETLSTSRTSVVNVLDRITQELAEEEIELSNVPRKGYMIEEYSFKR
                     FSYFITILKKMINIREIYSFYYQDNLYSKAGDLVFFDLFDLDILFDSLGETIQYSKQM
                     ASEIDDTNFLFLTILNYKYRELINAFEMTDRTEKLQMISSFISEIKQNNPNQMENNNL
                     AKRLIRYINRELADVFEVKDFKVASNALLYHIQRFIFRQENGIPFRDIDSEVLVKDHK
                     NLYYVIFAAIRSFQNGLFESVEAPEAVLITLYYINEIEKNAPKVFKAPRILIICGEGR
                     AISSVLKIKISNLIDSKWIDTISVFEFETPLIDHYDLIITTVRLPEVESDKVLYSDNV
                     FSESFFEQIKLKLSVGGYSFATQRLGKLSQIMNAIVEEVNDDINMNRLEAKIIKILAN
                     NLLQNNRPNEQKFIFDASMLKYHQAAQTWQNAIRISGQELLAKHSIEEQYVNNIISNI
                     ENFGPYMIIAPGVLLAHAGEQDGVLNNGFSMHVFHEPITFPGENVFPVSVIMTIAVKD
                     RTSYHVVERIVQWVLDEETIFSLADEKNRQRIEQMIRNILMMQEV"
     gene            8258..8569
                     /locus_tag="RD488_002409"
     CDS             8258..8569
                     /locus_tag="RD488_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7658459.1"
                     /translation="MTMTTDEISFALISKAGTAFSMMIEALGDAREKDFEKAEEKKQE
                     AEALMNEAHNLQTNLIVNEVNGDDNQINALLIHAQDTLMNTILMSTIVDEFLNLYKAG
                     E"
     gene            8571..8906
                     /locus_tag="RD488_002410"
     CDS             8571..8906
                     /locus_tag="RD488_002410"
                     /inference="COORDINATES: protein motif:HMM:NF014368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7658460.1"
                     /translation="MEKLSICLACNLGSSTSILVNKMKQVAAGSQKLSSFDLMIDAIP
                     AGNISTEQVKDYQIIMLGPQIGHRRNEIEQKVASINIPVTVIDAADYGSMNAANILKE
                     AIYQIKTAN"
     gene            8919..10154
                     /locus_tag="RD488_002411"
     CDS             8919..10154
                     /locus_tag="RD488_002411"
                     /inference="COORDINATES: protein motif:HMM:NF014437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658461.1"
                     /translation="MTLDYINQVVGKIQTKMIPTLGKIEGNQVFKSMKKTFLYLNYVL
                     LISSVLAILKLVNEKFIHQQQIADLTSKLLLLLMDNFGWFFLGILCFLMFQEKGKFHY
                     YLCSAALYLMFSAKDLNLLSASKIETLFLALLALLVSFVLVSGYQLVLRGIKKIIKTP
                     MEFLDNLLLMIYFSVIFMVIYQILSQLKGIHLENILSWLNIDNPMMVFVIVFLEMFLW
                     YMGINGYGILAPIVLLFAISNLNANFQAIATGEAPQFIFTPNFWDYFLSVTGSGITGA
                     IVILSLLSKKTTLKNLGRTAASGTLFSVSEPIVFGIPVVMNPYFFIPFVIGTPILGVI
                     QWYVFKLGWVSLPTYFVADLPLPFSSFLATMDWRSLILTAATIALATLMYWPFYKAFE
                     KSYVEKNNDDKYQDLDLDF"
     gene            10170..>10757
                     /locus_tag="RD488_002412"
     CDS             10170..>10757
                     /locus_tag="RD488_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7658462.1"
                     /translation="MLKSFFKIFCGNFILGLAYAKLMVPNEIINGGVTSLSLIFSNLT
                     SLNITLFTNVITVTLLAVSLLFLGKFFFFSSVVSSVSYLLFFNLFYRLPFSLHTNVVV
                     DFLLAVLLIAIGYYCCLSENSSTAGLDVFAVILNKKIPKISVAVFLRYINIAVLVLGL
                     FSYGIKAVILGVLFSFSFTKVMDLLMEKGADPRKFF"
BASE COUNT         3310 a         1771 c         2210 g         3466 t
ORIGIN      
        1 attaaaaaaa taaaatatgt cattcaagac gttgaaagcg attttagaat ttgctattct
       61 ttgggtgtgt tgaagagagc aaaaagaaag gggcttcaga atgaaacaag attcttattc
      121 agttaaggat gcaaacgtta ttttatcaaa attgatcttg ggttccagtg attatttgaa
      181 gttggacaac aaggacaagg tcgataggat gttcactaga tacgtagaag aaggtggacg
      241 aacttttgac actgccagac attaccgtga aagtgaggcg gtgattggca gttggttaaa
      301 ggataaaaaa cgtgaggatt acactattat cactaaaggt tgtcatccag tgcgggaagc
      361 accagatacg ccgcgtgtta atccagaaag tatcttagca gacttgacta ctagtttaga
      421 aatgttggca actgattatg tcgatgtgct tttactgcac cgagatgatc ctagccagcc
      481 ggtcggtcca ttaatggaaa ccttaagcca attggttgat gaaaagaaaa tccgatcttt
      541 tggtgtttct aactgggagt taccacgaat tattgaggca aaaaaatatt gtgaagataa
      601 cggattaaat cctttgtcat tcaatagtcc aaattttagt ttagccaaag ttaatgagcc
      661 tcgttgggaa aactgtgtga cagcagacga tctgatgatt gcttggcatg aagaaactga
      721 ttttcctttg atttcttggt cggcacaagc agaagcattc tttggaaatc gcttctcacc
      781 ggatgatgtt aacgatccgg agatggcaga gtttgttgct gtttatttta atgacttgaa
      841 ttggaagcgc ttagtgattt gtgaagagtt ggcaaaagaa aaaggtgtca agccaatcca
      901 aatttctctg gcctacgtgt taagtcaaac tttcccctca tatgccacaa ttggtccgga
      961 ggaagaatgg cagttacttg attcagttga agcgatgaat attcaattat ctgctgaaga
     1021 aatcatgcgt ctgaagaaag gagaataagc cagttggata aaacaaagat tgcggcccaa
     1081 atgtattccg tccgtaaaga actggaaaaa gatccagaaa atacttttaa atcattgaag
     1141 gaaattggtt ttgaagccgt tcagcttgat ggtatgcggg ggcacaaaga aactgaaatc
     1201 aaagcattag ttgataagta tggtttcaaa attgccggga tgcacattaa acatgatcgt
     1261 tttttcaatg atcgagacgg aattatttct gaatcattat tgtttggttg taaaacaatc
     1321 tacgataaat atatcgatga tgaagagcaa catacgaaag gctatatcca aacgaaacaa
     1381 caattggtca cgactcaagc gactcttgga aaactcggtt ttagaatcgg ccttcactgt
     1441 ccggaatatg attttaatca aacagtcgaa gggcggacca ttttggatta tattacagac
     1501 ccagtttttg ggacggcggt ctatgcggag ccagatactt attggatctc ggtagctgga
     1561 aaagatcccc tagaagaatt tagaaaattc tctggtcggg caccgattgt tcatttgaaa
     1621 gattacatca aaggttttgc accggaagat atggataata acttgacgga attaggtaac
     1681 ggagacgtcg attttaaagc cattgttgaa tggggcgaaa aaagtggtgt tgagtactac
     1741 tgtatcgaac aagattattc caaaatcggt atttttaaca gtttagcgaa aagttttgat
     1801 cacttaatgt caatttaatc ttaggagcga gaagatgaag aaaaatagtc gtattgtcat
     1861 gatgggtgtc gcattggtaa gtggtttggt attagcaggt tgtggaaatg gcagtgcctc
     1921 aaatagtgat aaagtggaat tatctatcaa ctattacaat ggtgcgatca gtaaaaaaac
     1981 catggataat gctaaaaaag aattttctga ctacaaattg agttttaaac aaattcctgc
     2041 caatgatgat tttgatacaa agctaaaagc cagcttaaat tcaaaatcgg caccagatat
     2101 cacagcaatc aacagtaata tttctgatta cctgccatat gctgataaat tcgtaaacct
     2161 attggattac gatagtgaaa cattagccgc tgactttgtt gaatggaagt gggattcttg
     2221 ttttacaaat gacaaaaaaa cgcagattgc catgccaatt gatattggcc caacagcttt
     2281 attctataat gtagacgctt tcgcaaaagc tggtttgcca acgaacgatc aagaaatcag
     2341 taaagcattg aaagatgagg aaagcttgat ggctgctgcc aaacaaatga aagaaaaagc
     2401 cgatatgcct ttcttccaat cttctctttc attgttgcaa tctaaaaatc gcacgatgac
     2461 tgaacatatt tacgatgaaa atggcaaatt gacctacgct aacggtcaat taaaagaaat
     2521 ctgggattac gctgttaaag cagaaaaaag cggttacact ttgggaacaa aaggaaatag
     2581 tgctgatggc gccaactccg ttcaaaaagg catgtttggt ggcatgatcg aagcttcttg
     2641 ggggatcaat gacttagctg aaaatggcgt ttcaccaaaa caatggatga tcgcaaaatc
     2701 tccatttacc gcgtctaact acggtggttc atatttggcg gtgatcaaaa cttcaagcca
     2761 tccaaaagaa gctgcggaag ttgtgaaata tttgacgaat gaagacagcc aacgggctaa
     2821 ctacgaagaa ttggctttat tcccatcaaa tactaaagtt tatgatgatt ccttcaaagc
     2881 agcgaaaaat gaattattcg gtgatgaaga atttaatcac tactttatcg atgccgctaa
     2941 cgaattggaa tatgtaccat cagatccacg tgaaagtgct gctttcaaat gtttcgaaga
     3001 ccaaatcatt ttggtagctg aacaaggcaa agatcctgaa aaagcttgga acgatgccgt
     3061 gaagaaagta gaagagatgt ctaaataatc agaatgtgat ttcgggatat gacatcgatc
     3121 aaattttaaa aattggtggg tgtcatagac ccgtaaatgg aggtctaagg atggagattg
     3181 gtgagatgat gaattcagaa tcgaaatcaa aaaagaaatt tagttttgat aaagttgccc
     3241 cttacgtttt tgtatccccg ttttatattt tgtttttgat ctttggtctg tttccagtta
     3301 ttttctcagg cgtcctggcc tttagtaaat gggatggctt aggggatatc caatttgtcg
     3361 gtttggataa ttttacccgt ttattgcggg atgctgactt ttatttatca gtcaaaaata
     3421 cgctaatcat ctgggcagtt gggacattcc cgatgttgtt tttggcacta atattagctt
     3481 tcttagtaaa tttgaaattt atcaaacata aagagttact aaaatcgata tttttcttac
     3541 caaatatcac ttctgttgta gcggtgacaa ttttatttgg cttgattttc tcaaatctgg
     3601 atggcttagc caatgcgcta ttacagtttt taggatttga accaattaaa tgggttacgt
     3661 caccattttg ggttcgaatc gtgattgctt tgatcaatat ttggatgtac ttaggctata
     3721 acatgatcat ttatctaaca gggattacaa aaattccaaa tgattactat gaagctgccg
     3781 ttattgatgg cgcaaccaat atgcagattt tttggaacat tacgatacct caattaaaac
     3841 cgattatctt gtttactgtg atgatgtcaa ccattggtgg tttgcaagtc ttctctgaag
     3901 cacaagtatt agtaccccag ggggcgactc ctgaaggtgg ggcgatgacc atcgtttact
     3961 acttgtataa tacggcgttt acaaacaatg agtacggata tggatcagca gttgcttggg
     4021 cattagtctt gatcattctg gtcttttcgt tgatcaactg gtacttgacg acttatcgaa
     4081 tcaaggggga ataaacatga gcaatcggat ttttaaaata cttgttagag ccttcttagc
     4141 gattggtgtc tttctttcga tcttcccatt ttattggatg attgtaatgg ccagtaaaga
     4201 taatagtgaa atctatcata ttccaccaga tttgatgcta gggtctgaac tgatgaataa
     4261 tatcaaaacg gtttttactg aaacaacatt ctttagctcg ttgcttaata ctttatttgt
     4321 ggcactaact tcgacactgc tgattttgtt ctttgattcc ttagcgggtt tttcatttgc
     4381 caagctgaac tttaaaagga aggcctttct ctttactttc ttattgggaa ccatgatgat
     4441 tccgggtcag ctgaatatta ttccttcatt ttatttgatg gataaatttg gttgggttgg
     4501 ttcttacaag gcgttgatta ttccagggat ggcaaatgcc tttggtattt tctggatcaa
     4561 gcagtattgt accgatgcca tccccgacag tttgttggaa tcagcaaaat tagatggttg
     4621 tacacttttt aaagcctatt acaaagttgt attgccaatt atgaaaccag ctttagcatt
     4681 tttagcactc tactctttta tgggtgcgtg gaatgactat atgtggccat tgattatctt
     4741 aaacgatgaa tcaaaataca cgttgatgtt ggctttgaca caactacaag gactttataa
     4801 aacaaattat ccattggtaa ttactggtac gttactggca actttgccac tactcttagt
     4861 ctttactatt ttcagtaagc aattgatttc tggtatcaca gaaggtgccg ttaagcaata
     4921 gaaagaggta ttagtgtgaa aacaaaacca cttagtatcg gagatacacc caagaataga
     4981 gcgcatggca aataaacgtc aaaaaccgca ggtctgacga ttatgaaagt tatttagatg
     5041 gctggctcta agtcttttct aacaaaatca tctggcaata aaccttctga aatcagtaat
     5101 ttggtcgctt gtttaattgc tttatctttc tgtttttgaa caagattgtc tggcatatca
     5161 atcttatata agtcagtcgg attccaaacc tcaccagttg aaagcatgtg gtagatagct
     5221 gtgagcatca ttcgagcaat cgtgatgata gcccgtttct taccacgtcg tttgtaaatg
     5281 cgcacgtact tcaaacggta gtacggattc ttttctttca ccaaaacggc tgcgtgtgta
     5341 catcaatacc acaacaaacg ggataaacga ctttcatgat tcttcgcccc tttctaaaag
     5401 tagcggagag gcagtgactg gtctgggcag catttaacag gatttgttaa aacaatgatt
     5461 agtgtgcgga cttctatagt tccgctcatt tgtgcttgaa cgccccgacc ttacactggt
     5521 taatatgctg gttcaaacaa tcgaggtttc ctacaactca cctcaccgtg ctttgtagta
     5581 tgcctctcct aattctatta taaacggaaa tccgcgtctt cattactatt tgactcgagg
     5641 agcggagcga gtcgagatgg aggttaatat gaaggaaaaa tttatcgcct tacaagcaaa
     5701 attaatggac ttgattttat tgagtggttt gatcttgatc ggggcaatga cgataattgg
     5761 tttcttttat ggaatcgttg cggcgtttgt ttatctagaa actaaaagtg aagataaatg
     5821 gcaagtttta aaaaaacgtc agacaatctt gattagtctc ttattagaaa tgtcagcagt
     5881 ttttgtagcc ggtatctttt tcctaaatgc gcgtttgctt tcgcagttgc aaggcggtgc
     5941 aacaattatc attagtttct ttttagccgt ttgtaccttg atcttaattc cactgtattt
     6001 cattttattg cacaagctag cagttggaac aatttttacg aaggaaacat ttcttaatag
     6061 tgtcaaggtc atcttaatcg gttttcctac ctggtttacc caaattatct taatgatcgc
     6121 gctgagtgtt ttgacttatc tgtttccggc tttatcgatc attacagttg ggtacttgat
     6181 tacccgcaca aataagatca ttaatgtgca aaaaatgaaa ttagctagtt tgcaggaggt
     6241 ctattaatga aattgagtca acgggaaatt gatcttttaa agctggcttt agatggtgaa
     6301 gaagaaacga ctgtgccgca actaaaaaaa caattgaagc tctcagtcca tcaaattcgc
     6361 tatgctattg ataaagtgaa ccgcttttta attgaaaaaa agttgaatca aatttttatt
     6421 gaaaaagatc ggctggtcat tgaacaacga cgaaaaatca aaaaagaaat tgattttttt
     6481 atatctcact cgacgccaga gcagtttaaa tttaccgcag agcaaattga atattttatc
     6541 tcattgaaac tgctgctaag tgatcaacgt ttgccaatca attattttgt agaaacatta
     6601 tcgacttccc ggacttctgt ggtaaatgtt ttggaccgaa tcacacagga actggctgaa
     6661 gaagaaatcg aattatcgaa tgtaccacga aaaggttaca tgattgagga gtatagtttt
     6721 aaacgatttt cctatttcat cacgattttg aaaaaaatga tcaatattcg tgaaatctat
     6781 agtttctact atcaagataa tttgtattca aaagctggcg acttagtatt ttttgacctc
     6841 tttgatttgg atatcctctt tgattcttta ggggagacga ttcagtattc aaaacagatg
     6901 gccagtgaaa ttgatgatac gaacttttta tttttaacga ttttgaacta taagtatcgt
     6961 gagttgatca atgcctttga gatgactgat cgaacggaaa aattacaaat gatttcaagt
     7021 tttattagtg aaatcaaaca aaataatccg aatcaaatgg aaaacaacaa tctagccaag
     7081 cgattgattc gctatatcaa ccgtgaatta gccgatgttt ttgaagtaaa ggattttaaa
     7141 gtggcctcta acgcactact atatcatatt caacgcttta tttttagaca ggaaaatggc
     7201 attccttttc gcgatattga tagcgaagtt ctagtaaaag accacaagaa tttgtattac
     7261 gtgatttttg cggcaatccg ttcttttcaa aatgggttgt ttgaaagtgt agaagcacct
     7321 gaggcggtat tgatcacatt gtattacatc aatgaaattg aaaagaatgc accaaaagtt
     7381 tttaaagcgc cgcgaattct gattatttgt ggtgaaggcc gtgcaatttc cagcgtgtta
     7441 aaaatcaaaa tcagtaattt gatcgattcg aagtggatcg atacgatttc agtttttgaa
     7501 tttgagacac ccttgatcga tcattatgat ttgatcatta ctacggttcg gttgccggaa
     7561 gtcgagtcag acaaagttct atactcggac aatgtcttct ccgaaagttt ctttgaacaa
     7621 attaaattga aactatcggt aggtgggtac tcatttgcga cccaacgcct tggcaagctt
     7681 tcacaaatca tgaatgcaat cgtcgaagag gttaacgatg atatcaatat gaatcgtctt
     7741 gaagcaaaga ttatcaaaat tttggcgaat aatttgctgc aaaataatcg tcccaatgaa
     7801 caaaaattta tctttgacgc cagcatgttg aaatatcatc aagcagcgca aacatggcaa
     7861 aatgcgattc gcattagcgg gcaggaactt ttggcaaagc actcgattga agaacaatat
     7921 gttaataata ttatcagcaa tattgaaaat tttggacctt atatgatcat tgcaccgggt
     7981 gtcttgctgg ctcatgctgg tgaacaagat ggcgtgctta ataatggctt tagtatgcat
     8041 gtttttcatg aaccgattac ttttccaggt gaaaatgttt ttccggtaag tgtgatcatg
     8101 acaattgccg taaaagatcg cacatcttat cacgttgtcg aaaggatcgt gcaatgggtc
     8161 ttagatgaag aaacgatttt ttcgttagct gatgagaaaa acagacaacg gatcgaacaa
     8221 atgatccgaa atattttgat gatgcaagag gtgtaacatg acaatgacaa cggatgaaat
     8281 atctttcgcc ttgatttcta aggctggtac agctttttca atgatgatcg aggcattggg
     8341 agatgcccgc gaaaaggatt ttgaaaaagc agaagaaaag aaacaagaag ccgaggcttt
     8401 gatgaatgaa gcccataatt tacaaacgaa tttgatcgta aatgaagtca atggcgatga
     8461 taatcaaatc aatgccttat tgattcacgc ccaagacaca ttaatgaata caatcttgat
     8521 gtcgacgatt gtcgatgaat ttcttaattt atataaggca ggagaataaa atggagaaat
     8581 tatcaatttg cttagcgtgt aatttagggt catccaccag tatcttggtg aataaaatga
     8641 aacaagtggc agccgggagt caaaaattgt cttcttttga tttaatgatt gacgccattc
     8701 cagcaggaaa tatcagcacg gaacaagtga aggattatca aattattatg ttgggaccac
     8761 aaatcggaca caggcgcaat gaaattgagc aaaaagtagc tagtatcaat attccggtaa
     8821 cagtcatcga tgcagctgac tatggcagta tgaatgccgc taatattttg aaagaagcaa
     8881 tttatcaaat caaaactgct aattaaggat ggatagccgt gactttagat tatatcaatc
     8941 aggtagttgg aaaaatccaa acaaaaatga ttccgacttt aggtaaaatc gaaggaaatc
     9001 aagtttttaa aagtatgaaa aaaacttttt tgtaccttaa ttatgtctta ttgatttcct
     9061 cggttttggc tattttgaaa cttgtaaatg aaaagtttat ccaccaacaa cagattgctg
     9121 atttgacgtc taagttgttg ttattactga tggataattt tggctggttt tttctaggga
     9181 ttctttgctt tttgatgttt caggaaaaag gaaagtttca ctactatcta tgcagtgcgg
     9241 ctttgtatct catgttttca gcaaaagatc tgaatttatt atcagcctct aaaattgaaa
     9301 cactattttt agcattgttg gctctgttag ttagctttgt tctggtgagt ggttatcaat
     9361 tagtgctgcg gggaattaaa aagatcatca agacaccaat ggaattttta gataatttgt
     9421 tactgatgat ttatttcagc gtgattttca tggttatcta tcaaatattg tctcagctta
     9481 aaggaattca tttagaaaat attttgagtt ggttaaacat tgataaccca atgatggttt
     9541 ttgtcattgt ttttcttgaa atgtttcttt ggtacatggg catcaatggc tatggcatat
     9601 tagcgccaat tgttttacta tttgccatta gtaatttgaa tgcaaacttt caagcaatcg
     9661 ccacgggcga ggcaccgcag tttattttca cgcctaattt ttgggattat tttctaagtg
     9721 ttactggatc aggaattact ggcgccattg tgattttatc tttgttgagt aagaaaacaa
     9781 cattaaagaa tctcggtcga acagccgcta gtggaacctt gttttcagtt tccgaaccaa
     9841 ttgtttttgg gataccggtg gtgatgaatc catacttttt tatccccttt gtgattggga
     9901 ctccgatttt aggggttatt caatggtatg ttttcaaact tggttgggtt tcattaccga
     9961 cttattttgt ggcagattta ccactaccat tttcgagctt cttggcaacg atggattggc
    10021 gttctttgat tttgaccgcc gcaaccattg ccttagcaac tttgatgtac tggccgtttt
    10081 ataaagcatt tgagaaaagt tatgtagaaa aaaataatga tgataagtat caggatctag
    10141 atttggattt ttagaaaaga ggaataaaat tgctaaaatc tttttttaaa atattttgcg
    10201 gaaactttat tttgggctta gcatacgcca aactgatggt tccaaatgag atcattaatg
    10261 gtggtgtgac gagtctttcg ttgatattta gtaatctgac ttccctcaat atcaccttat
    10321 ttacaaatgt catcaccgtg acattactgg cagtttcatt gctcttttta gggaaatttt
    10381 tctttttctc ttccgtcgtt agcagtgttt cttatttgct gtttttcaat cttttctacc
    10441 gcttgccatt ctcactacat acaaatgttg tggttgattt tcttttggca gtattgctga
    10501 ttgccatcgg ttattattgc tgcttgtcag aaaattcttc tacagcaggt ttagatgtat
    10561 ttgcggttat tttgaataaa aaaatcccca aaatctcagt ggctgttttc ttgaggtata
    10621 ttaatatcgc agttttagtt ttggggctgt tttcatatgg aatcaaggcc gtcattttag
    10681 gggttttatt tagttttagt tttactaaag taatggatct tttgatggaa aaaggtgcgg
    10741 atccccgcaa atttttt
//
LOCUS       DAPBBR010000079        10742 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPBBR010000079 DAPBBR010000000
VERSION     DAPBBR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.083"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(57..2654)
                     /gene="adhE"
                     /locus_tag="RD488_002413"
                     /gene_synonym="adhC"
     CDS             complement(57..2654)
                     /gene="adhE"
                     /locus_tag="RD488_002413"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDT7658463.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2959..3339)
                     /gene="yajC"
                     /locus_tag="RD488_002414"
     CDS             complement(2959..3339)
                     /gene="yajC"
                     /locus_tag="RD488_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDT7658464.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3436..4581)
                     /gene="tgt"
                     /locus_tag="RD488_002415"
     CDS             complement(3436..4581)
                     /gene="tgt"
                     /locus_tag="RD488_002415"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDT7658465.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4799..5497
                     /locus_tag="RD488_002416"
     CDS             4799..5497
                     /locus_tag="RD488_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7658466.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5665..8304)
                     /locus_tag="RD488_002417"
     CDS             complement(5665..8304)
                     /locus_tag="RD488_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7658467.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8923..9954)
                     /gene="queA"
                     /locus_tag="RD488_002418"
     CDS             complement(8923..9954)
                     /gene="queA"
                     /locus_tag="RD488_002418"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDT7658468.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10147..>10742
                     /locus_tag="RD488_002419"
     CDS             10147..>10742
                     /locus_tag="RD488_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7658469.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         2956 a         2312 c         1978 g         3496 t
ORIGIN      
        1 gttttccaag ttctttttca tctattttct tatctttttt ctacgctttc ttttgcttat
       61 ccgttgtaag catcaatgat gatctgtttc aattcagaga tcaatggttc tttcggatta
      121 gctgtcgtac attggtcttc gtaagctaat tcagccatac ggtctacggt tgtatctagt
      181 gtttcttgtg tgactccttg agcttttaga ctcatgttga tgccgacaga ttttcctaat
      241 tcataaacag ccgttgctaa agcttcgact aattcctctg ttgtttcgcc tttcagacct
      301 aagaattttg cgatatctgc gtaatctgta tctgcacgga aatagtcata tttagggaac
      361 atcgcatgtt tttgtggatc ttttgcatta tagcggataa tatgcggtaa aagaatcgca
      421 tttgtccgtc catgagggat cccgtattcc ccgccgattt tatgtgcgac tgagtgacaa
      481 atacctagga atgcgttagc aaacgccata ccagccattg tagaagcgtt gtgcattttt
      541 tcacgtgatt ccatatcagg tgtttttact gatttttcta aatagtcaaa gactaacttg
      601 attgcttgta ggctcaatcc acgtgtataa tctgaagcca tgactgaaac ataggattcg
      661 attgcatgtg ttaacacatc catcccggta tctgctgtga cagatgctgg aactgacatg
      721 acgaattgag gatcgacgat tgcgacatct ggcgtcaatg cataatctgc taacggatat
      781 ttcacatgtg tttcactgtc agtgatgacc gcaaatggcg ttacttcaga accagtccct
      841 gatgttgtcg ggatacatac gaattgtgtt ttttctggtt tgtcgatctt atatgtccgt
      901 ttacggatat ccaagaattt ttgttttgca ccaaagaaag atgtgtctgg gtgttcatag
      961 aacatccaca ttcccttagc tgcgtccatt gcagaaccgc ctccaagagc gattactgta
     1021 tctggcttga agtctgccat cagtttcgtt cctgcgtata cggtatttgt cgatgggttc
     1081 ggttcaacat ctgagaagac ttcgatcttc acatcatttt tacgtcgtgc caatacttca
     1141 cgaactgtat cgcagtaacc gaattggacc ataccagggt cacaaacgat catgacacgt
     1201 tcaacgtttt ccattttctc taagtacaat agagagttct tttcaaagaa gatttttggc
     1261 ggtaatttga accattgcat gttatttctc cgtttcgcta cagttttgac attgattaag
     1321 tttacagcag agacgttacg agaaacagag ttcttaccat aagaaccgca tcccaaagtc
     1381 aatgacggaa tcatttcgtt atagatatca ccgatgccgc cttctgcaga tggtgtattc
     1441 actaaaatac gacaagcttt cattcgaaga ccgaatttga catgcaactc ttcgttttct
     1501 gaatggataa ctgctgtatg tcctaatcct ccaagattca acataccttc acacaaatca
     1561 aacgcatggt ccgtgttgtt agctttgatc atggcaagaa ctggagaaag tttttctctt
     1621 gatagcggat aatctgggcc tacgccttcc aattcagcaa tcagcatttt cgttcctttt
     1681 ggtacactga ttcctgccaa ttttgcgatt tccatcgcag aatgtccaac gattgatgga
     1741 ttgaccgcat attttccttc gttcatcact gcatcttcta atttttgcaa ttcatctggt
     1801 tttacgatat aaacttggtg tgcttggaat tctgctttta ctgctgcata gatttcttta
     1861 tccacgatca cagcttgttc agaagcacaa atcattccat tatcaaatgt tttcgaaacg
     1921 atcaaatcgt tcactgcacg tttaattttt gctgtttttt caatataagc tggtacgtta
     1981 cctggaccta cacctaaagc tggttttcct gtagagtaag cagacttgac cattccagct
     2041 ccacctgtcg ctaagacgat cgcgatacct ggatggttca ttagcataga agtcgcttcg
     2101 atcgaaggat gttcgatcca ttggatacaa ttttcaggag ctccggcagc gatagcagca
     2161 tcacgtacca ctcgtgctgc ttctgcagaa gatttttggg cacttggatg gaaagcaaaa
     2221 acgattggat ttcttgtttt caacgcgatc attgatttga aaatcgttgt ggaagtcgga
     2281 ttcgttgttg gagttactcc gcaaaccaca ccgactggtt cagcaatttc aatcaaccct
     2341 ttttggacat cttcattgat cacaccaact gttttatcat gtttgatatt atgccaaata
     2401 tattcggacg catacatatt tttgattgct ttatcttcgt aaacaccgcg gcctgtttcc
     2461 tctacagcca tcttcgctaa tggcatatgt tgatccaaag ctgccattgc catttcatgc
     2521 acgatatggt ctactttttc ttgatcaaag ctttccattt ctttcaatgc tgcatttgct
     2581 ttttctgcca aatcatcaat cattgcttgt acgtcaattg tcttcgtttt ttctttttct
     2641 attactttag ccatcattat cctcctaatg ggtcatggtt atttgttaaa taattcacat
     2701 gtatatcata caatatttat ttttctatgt aaacactttt ttgtgatttt tttcacagtt
     2761 atttttaaat ataaaattgc tttatttaca ggtgtttgta tagaaaaata tataaagtta
     2821 tttattatta tttatatgac acacccgatt attcaatatt gagcaatata tcccatgctc
     2881 ttatctcttt cttttttgaa taaaaaatga ggtaggacat ctttctgccc tacctcgtct
     2941 ttaaataagc tttgatactt atttttcttc cttctcttct gtctcttcca gcgtttctgt
     3001 tgtttcagtt tttacttcaa ctgtctcagc tggttcttct gttgtttcaa cagtagtcgt
     3061 tgcatcattt gttacgacag tccctggttt gaccgttttg attgctgcac gatcgtactc
     3121 aaggaagatc ccttcgcagt ctaaaacaac tgtccgtttg tcattgtcga tttctgaaac
     3181 aactccatgt aatccgccga tcgttacgac tgaatcacct ggtttcatgc tatctaacaa
     3241 gttttgacgt tcttgctgtt gtttcttttg cgaacgtgac ataaaaaacc acattgctaa
     3301 tagcgcgata aacatcacaa gcattggtaa tgttcccatt tttttcacct cactaattct
     3361 gtatctacaa aaaacacttt agcagaaaaa tgctgataac actagttttt tacttaattt
     3421 ttaaaagatt ttcctttaga agctttttgc gttttcttta ttgaacccgt attcttcaaa
     3481 aaaggcttct ctaaattcaa gcaaattatc atccatgatt gcttgacgta cttgtttcat
     3541 tagattcaac aagaagtata aattgtggta agaagtcaaa cgaatcccaa atgtttcatc
     3601 acatttgatc aaatggcgga tataggcacg tgtatagttt ttacatgtat aacaatcaca
     3661 tttctcatca attggacgga aatcatgggc atatttcgca tttttcacta ctagacggcc
     3721 ttgagaagtc atacatgtgc catttcgagc gattcgagta ggcaagacac agtcaaacat
     3781 gtctactcca cggataacac catcgatcaa tgaatcagca gcaccgacac ccatcaagta
     3841 acgtggtttg ttttcgggga tcaacggtgt agtgaattct aatacacgat tcatttctga
     3901 tttaggttcc ccgacagata acccgccgat tgagtaacca gggaaatcca tcccgactag
     3961 atctttcgcg ctttgacgac gaagatcttc aaaccctgct ccttggatga ttccaaataa
     4021 tccttgacgg tctggattag catgagcttt caatcctcgt tctgcccatc gagacgtacg
     4081 ttctactgat tttttcacgt agtcgtaact ttcatcgaat ggtggacatt cgtcaaaact
     4141 catcatgata tcagagccca atttattttg gatgttgatt gctttttctg gtgataaaaa
     4201 catacgcgaa ccgttcaagt gatttttgaa atgcacgcct tcttcttcga tattccgcat
     4261 atcacttaat gaaaaaactt gaaagccgcc tgaatctgtt aaaatcggtt gatcccagtt
     4321 cataaattta tgcagtccgc cagcttcttc tactaagtct tcaccagggc gtagccataa
     4381 atgatatgta ttacttaaaa taacgccagc acccatttct ttcaactctt ctggggacat
     4441 tgtttttact gtagctaatg ttcctactgg catgaacatt ggtgtgggga aagttccgtg
     4501 tggcgtgatc aattccccta aacgcgcgcc agtatgtttt tctttcttga ttaaacgata
     4561 gcgaatggca ggttgcgtca ttcatttccc tactttctat ataaaatatc ttgacaactc
     4621 ccaccatcat aatcgtttca agtgcttttt gcaagttccc tcggcttcct tctactttat
     4681 ttaatattct tttttttatc ctttttttat gaataacaaa aaaaagaaaa acattatgac
     4741 agaaatattt tttgatacat ggtatattgg tgttattaaa gaaaaggagg gaaaaatcat
     4801 gcaatcttct gcagaattaa aacgccaagc aaaagagagt ctaaaaggac gttggggaca
     4861 agctgtttta ctaaatctaa tccctacatt gattggtatt gctactattc ttcttattat
     4921 gattcctatt atcttgtttg ccaccaccat atatgatgga tcagcgagcg tctcagaagc
     4981 gacaacttca ggaggcggta gttcaggagg cggtggcgga attatttcca gcatcattag
     5041 cgctttgttc atgagcggta tttcttggac ttatcttgat attttacgtg gacaaaaaga
     5101 tcagatcgaa ccattcaaag atgcatttcg tggattcaaa ggtttgttta tcggcggagt
     5161 gatcagctta gctgtgctga tctcgatctt tacaacatta tggggtttgc tattagttat
     5221 tcctggaatc attaaaagct attcttattc tcaaagctat tttatttact acgatatcgt
     5281 ccaagaaaca ggacaaacac ctaaagtact ggatacgatc actgcaagtc gaaaattgat
     5341 ggatggttat aaaggacaac ttttctggtt agatctttca tttatcggct ggcatatctt
     5401 agcattagca actgctggta ttggttatct atggctcagc ccatacattt ctgcaacaaa
     5461 agcagcattt tatgaacaat tgccaaaaga tatttaaaag agagtgtgac ttgtgaccga
     5521 gggggtggca ggagaacacc gtttatcgag aggcagtaaa agaaacattc agcccattag
     5581 caaaaaggag gtgtgacaac attcatgtca cacctccttt ttgtatagtt ccagtaaaaa
     5641 gaaaatcaac ttagaaacag ttaatcattc ctcttcttct gcttccggta atcgatggaa
     5701 cttgatcagt tcattcaccg cgattggtac gatagataaa atccctacca agaaccagtg
     5761 attcaaactg atgtgtacta ggccgaatag ttcttgcgta aatggcagca aagcaacagc
     5821 cgttgtaata gctaatgcca gtaacgccat ttctaccaaa gctttattgg tcgctaaatt
     5881 gactttgaag atcgattggc tgctgcgtac attgaacaca tgcagaatcg atgaataagc
     5941 taagatcaag aatgcaacag tttgaccgac atgctgactt gcgtctaccc atgggctgat
     6001 agtatcgaca taactaccta aataataacc aaacaaggtt acgatggtga agacccctgc
     6061 atttatggca attttttgca ataaacctcg agcaaagatc ccttcatttt tcggaatggg
     6121 tggctgatcc atgatgccgt gttccgctgg ctctcttcct aaagcaaatc ctggaagtcc
     6181 atcagcaact acattgacaa acagtagttg cacagctgta aatggtgctc cccatcctaa
     6241 cagcatcgca atcaaaacaa taaagatctc cgaaatatta cagcttagca aaaagttgat
     6301 agctttacga atattctgat aaaccgaacg tccttgactg acagcgtcta cgatcgtcgc
     6361 aaagttgtca tccgtcaaaa tcatatctgc ggcactttgc gccacatctg ttcctgtgat
     6421 ccccatggca cacccaacgt tacttgcttt caacgctggt gcatcattca caccatcccc
     6481 agtcatcgct acgactgcac ccgtacgttg ccaagatttg acgatccgga tcttgtcttc
     6541 tggcgttacc cgagcataga cagagagagc tttgacacgc gcatctaatt cttcgtctga
     6601 taattgatgc agttctgatc ctgaaagtgc ttctgacgga tcattcaaga tacctaattc
     6661 tttcgctatg gcactggcag tcaccacatg atctccagtg atcatgactg ttttgatgcc
     6721 agcctttttc gctcgcttga ttgctccttt actttctgga cgtggtggat cgatcattcc
     6781 gatcagacca atcaaacgta agtctttttc cagtgcttca gaagaaatat cttgcggttc
     6841 ttcgtcataa gtagcataac caacagcaat cactctcagt gcccgtttac caaagcgatc
     6901 attaacgatc gccgcttgtt ctacatcgcc tgaactaaag cgcggagcaa gaacatcgaa
     6961 tgctcctttg gtgattgaga tgtatttttc gcccatttgg tgaactgttg tcatcatttt
     7021 tcgttcagaa tcaaaaggaa gctcgtttac tcgtggatat ttttcttcta attctgcctt
     7081 tgtatgataa ttctcttcaa cagcccttac gatggctact tctgttggat tacctttgat
     7141 aacaaggtcg tcatcttctt gctcgaccgt cacatctgta catagtgcag ccattttcaa
     7201 tatttccatc gcgctgttcg tcattgaatc ttcgatattc gttacttcat cttctttgct
     7261 ccatacccgg cggacgcgca tttcattttg tgtcagcgtt cctgttttgt ctgagcagat
     7321 aacattagcg gttcctagcg tttcaactgc tggcaactgt cggatgatcg catgtttcct
     7381 cgccatcttc tgcacaccgt atgcaagtgt caacgtaaca ataacagtca aggtttccgg
     7441 tacagctgca acagccaagg aaatcgaagt catgaacatc tcaaggagtg gttctccttg
     7501 cagttcacca atcacaaata ctaaagccgc agccgctaaa gcgatcatac tgattcgttt
     7561 gcctagctga ttcaatcgga cctgtaaagg tgttttttgc atagtatttt cgttcaaaag
     7621 atccgcgatc ttacccattt ctgtagccat gccaatggca gtgacgatcg ctttcccacg
     7681 acctgcagca accgtacatc ctttaaatac catattaagt tggtcaccta atgactcatc
     7741 ttcttcagca ataaatgctg catctttttc aactgcttca ctttctccag tcaacgccga
     7801 ttcttctaca cgtaattgtg atgcttcgat caaacgggca tcggcagaaa tagcatcacc
     7861 ggactctaaa acaagaatat cacccactac cagttgctct gactcaacag tggtcacttt
     7921 gccgtctcgt atgacagttg ccgtttgttt attcatatct tgcaaggatt ccagtgcttt
     7981 ttctgcgttt ccttcttgga caatcgccaa taccgagttg atcacaacga tagcgatgat
     8041 cagcagtcct tcaaataaat ccccatgttc tgtagcaaat gcggtataaa aggaaatcac
     8101 cgctgctaca agaaggatga tcgttgtaaa atcggacaag cttcgaaaga attttttgat
     8161 catcgattct ttcggcgcct catcgaattt attcaatccc tgcttttttc gccgttcatc
     8221 cacttcttgt gaagacaacc cagtatctgg atctgcttct gttaccttct ttacttcttc
     8281 tattgtctgc ttgtattctt ccatcctatt cctcctttaa aatcttcgta caaaaaaagg
     8341 tacttatttt actataacat ccttttttta tttacttcaa ataaagggct tatcgattat
     8401 ttgttaagaa agcgtaaaat ttaaagtgct tatatttgca aacgctacca aaggatgcta
     8461 ttatatagat gtaaggaagg aggataccat caaatagaca gaagaatttc tcgatagaac
     8521 agtgtaagca aacaaagttg ttagaagtac aggtttcacc cagacatgcg tgtagagtac
     8581 aaacctataa atagtgaatg cgtatggatg tttggatcac gaagtatccg aaacaagaag
     8641 taatgcgata cgtaacaatt gaataacgta aacgtctgaa aattgaatag gaacaagaga
     8701 tgtttcaaat gttgaagatg taacgaaaac aaaatttttg tttaacatga agaaattcaa
     8761 caccgtgctt tgcatgtatg atggaaagtt acaatcattt ctgtttattt gaatccttcc
     8821 gaggtacaag aaagccgagc ttatcgagag ctcggctttt tctttgtcat aaaatctttg
     8881 taaagctttt ttgttattca aaactagcgg cttttcataa ccttatttca cgaacatcgc
     8941 atctccaaaa ctaaagaaac gatagcgctc ttcaatcgca tgctggtaag cagataaagt
     9001 caattctctt cctgcaaagg cactaactaa catgactaaa gtcgattttg gcaaatggaa
     9061 attagttgag aaagcttcta ccactttgaa ttcatagcca ggcgtaatga aaatatcagt
     9121 ccatccgctg tctgctttga tttctccatt aaatttcgtt ccaatcgttt ctaatgttcg
     9181 aattgaagtt gttccgacag ccacgatttt cccgccattt ttacgtactt ggttcaatcg
     9241 ctcagccgct tcttccgtca aacggtagaa ttcactatgc atatggtgtt cttcaatttt
     9301 atctacgctg acaggtcgga atgtacctaa ccctacatgt agtgtcagat agactaattc
     9361 aacacccttt gcttcgatct catcaagtaa ttctttcgta aaatgcaatc cagctgttgg
     9421 cgctgcagca gaaccatttt ctttcgcata gacagtttga tagcgatctg ggtcttccag
     9481 acgttctttg atatatggag gcaatggcat ttctcccaat gattcaagaa tctctagaaa
     9541 aattccttca tactcaaagt caatgatccg tccgccgtgt tccaattctt ctttcactac
     9601 tgcttgcaat ctgccatcac caaaagagat tcttgtccca actttggcac gtttcgcagg
     9661 tttgatcaat gtctcccacg tatctccttg tgtattcgtt agaagaagga cttctaaatg
     9721 cgcaccagta tctggttttt ctccatataa acgagcaggc agaactcgtg tattattcat
     9781 aactagcgca tcaccaggct gtaactcttc aatgatttca tggaaatgtt tatcttccat
     9841 ctctccagtt ttccgatcca aaacaagtaa acgagaatga tcgcggtctt ttaatggtgt
     9901 ttgtgcgatt aattcttccg gcaagtcaaa atcaaaatct tctgttgtta acatatcgtc
     9961 actcactttc tatcatgtgc ttcatcattc tatcatgttt ttcgttctgt tggcaaaatc
    10021 agcacttttt cacttctatt ttttgttttc ctaaataaaa aaactaccct atttgtattt
    10081 tttcattgtt ttaggcatac tagtaataga tagttcttca ttgaaaatag aaaaagaggt
    10141 ggcaccatga ttgaatttca aaatgtgtca aaaatttata aaggtggaaa agtcgctgta
    10201 gaggacgtca atctttcatt tgaaaagggt gagttcattt gttttatcgg tacgagcgga
    10261 agcggaaaaa cgacgacgat gcggatgatc aaccgaatga ctgatccaac acaagggaaa
    10321 attttgattg atggaaaatc catccaagaa attgatccag tggaattgcg acgtcagatc
    10381 ggctatgtta tccaaagtat tggattgatg cctcacatga cgatccgtga aaatatcact
    10441 cttgtccaaa aattgttgaa agtcagtcaa gaagaacgga ataaaacagc tgaaaaaatg
    10501 attgatcttg tggaattgcc ccgtgagatg ttagatcgct acccacatga attatctggt
    10561 ggtcagcagc agcgtattgg agtcgttcgt gcccttgcag cgaatcaaga tatcatcttg
    10621 atggacgagc cattcggtgc gcttgatcca atcactcgtg attccttgca agaccttgtc
    10681 aaagatttac aagagcgttt gggaaaaacg atcgtatttg taacccatga catggatgaa
    10741 gc
//
LOCUS       DAPBBR010000080        10616 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.084, whole genome shotgun sequence.
ACCESSION   DAPBBR010000080 DAPBBR010000000
VERSION     DAPBBR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.084"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            288..2234
                     /locus_tag="RD488_002420"
     CDS             288..2234
                     /locus_tag="RD488_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7658470.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2237..2692
                     /locus_tag="RD488_002421"
     CDS             2237..2692
                     /locus_tag="RD488_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7658471.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2706..4034
                     /locus_tag="RD488_002422"
     CDS             2706..4034
                     /locus_tag="RD488_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7658472.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4068..4352
                     /locus_tag="RD488_002423"
     CDS             4068..4352
                     /locus_tag="RD488_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7658473.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4354..4869
                     /locus_tag="RD488_002424"
     CDS             4354..4869
                     /locus_tag="RD488_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDT7658474.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4885..5547
                     /gene="rpe"
                     /locus_tag="RD488_002425"
     CDS             4885..5547
                     /gene="rpe"
                     /locus_tag="RD488_002425"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7658475.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5554..6126
                     /locus_tag="RD488_002426"
     CDS             5554..6126
                     /locus_tag="RD488_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7658476.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6313..7833)
                     /locus_tag="RD488_002427"
     CDS             complement(6313..7833)
                     /locus_tag="RD488_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7658477.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8076..8261)
                     /locus_tag="RD488_002428"
     CDS             complement(8076..8261)
                     /locus_tag="RD488_002428"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDT7658478.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8245..8427)
                     /locus_tag="RD488_002429"
     CDS             complement(8245..8427)
                     /locus_tag="RD488_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658479.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8668..8886
                     /locus_tag="RD488_002430"
                     /pseudo
     CDS             8668..8886
                     /locus_tag="RD488_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9381..9980
                     /locus_tag="RD488_002431"
     CDS             9381..9980
                     /locus_tag="RD488_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7658480.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10044..>10616
                     /locus_tag="RD488_002432"
     CDS             10044..>10616
                     /locus_tag="RD488_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HDT7658481.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3511 a         1670 c         1981 g         3454 t
ORIGIN      
        1 tataataaaa aaatacgaat tttagtgacg ccattatatt gtttttattt ttcaattgta
       61 atatttcata ttacttccat aataaggagt attttctatt ggaatatctt agctctttta
      121 aggatttctc cttttttgtt tctcattttt taagattatt tggatttcct ttacaacaaa
      181 cttccacaag tattattgac atagatgtaa ttgagggaag ggggttccag tgctagaata
      241 aataatgaaa agaggtaaca aatgctagcg ttaagaggtg aacaagtttg attgaaagac
      301 atgtaaattt attaaaatta ttaagtcgac aagaagactt taaacccgct tcttttttta
      361 gtgataaatt ggcagtgtcg accaagacca tttatcaaga tattgaattg ttggaagatt
      421 atgtagttaa ttaccaagta acaattgagc gattaccttc tttgggtatc aaactcatag
      481 gtgataggaa aaacgttgaa catttgattt catcggtaga aaattatctt gaaaaagata
      541 tttattctcc agaaaaaaga cgtgtcgaga tcattaaaga agttttgttt ggtgataagc
      601 ctgtttcttt aactcatttg tctcaaagtt ttatggttag taaaacatcg ttatacaatg
      661 acctgagaat tatcaataaa attattggca gtggagaagt taagttgcag tcatctgcag
      721 aaggaattag ttttactggt aatgaacaag caattcaacg agcaatcaag caacttgtat
      781 tctattatgc gaatgacatg gaatcaaaaa cattttttca agttttaaat atgttgtttg
      841 attcaaaagt tattagtgtc attcatgatt tgctattcaa tgattacagt gaactgactg
      901 aaaaggtttc tgattactat gttcggtcat tgatttctac tttagttatc caatgtaacc
      961 gtttactgaa aggtcatcat ttaactgttg aagaagaatt cctcttcaat agcattcgct
     1021 atatggaaac gtacattgtg gcaaatggtt taattgaaga attgaaggca aaattgaatc
     1081 ttccatttta tgacgcagat aaagaatatc tatgtcgtca actatttgca catcgtgtga
     1141 caaataattt aaaaaccagc aatgaagagt acgctatgag cgttcataaa ttgattgaaa
     1201 gaatgagtga gattgaaaaa attgatttga ctcaaaatga tcgattatat caatccttat
     1261 tgtatcatgt gccagcaatg gtccttcgtt taaaaaaagg tattaaaatt caaaatccgt
     1321 tattagaaaa tatcaaatct caatattcag aactctttag catagtatgg tacgccatgt
     1381 ccatccttga agaagaattt gatgtgactt taacggacga tgaagtttcc ttaattttga
     1441 ttcattttca gattgctatt gaagatcagt ccaaagcaaa taatatcatc attatttgcc
     1501 aatacggtat ttcttctgcg caattaattt acaataaagt tcgacggttt ttaccagcaa
     1561 aagataatgt agaaatatca actttagata agtttcattt agctgaaatt ggggaagttg
     1621 atttgattat ttcctctctt tcctttgatg caggtggtat acccttagta agggtatctc
     1681 cattggtaag taaaacagat tatatgaata ttatggaagc ttatactaaa tatttaatag
     1741 aagaaccttc gcgatttatt caaaatgaac tgattcctaa agcggttaaa gttcccacca
     1801 tatctaaatt tgttcaatca tctttagtaa aaacaggagt acaggtggaa agcaaagaag
     1861 aatgtttgga tttgatgatt tccgaactag aagccaattc attagttact gaagagtttc
     1921 gtgcttctat cttctctaga gagaaaatgg ggaatactaa tttagaaagt ggtgttgctt
     1981 taccgcatgc gaatccatca atggtcattg aatccaacat ttttattgta gcattaaaaa
     2041 atgcgattaa ttggggcgat cgaaaagtca aattagtcat tatggttagt ttagctgaag
     2101 aagatgtatc tgagattaga ggagtatatg aagaacttta ccaatttatt gggcaaaaag
     2161 aaatggtcga tcgcttgtta caagttcatg atagcgaaaa attactaaga atttttcaac
     2221 aaaaaggaga ataaaaatgt atctagataa agaattatgt ttatttcaat tagaagtgaa
     2281 agatcaaaaa gaattgtttc aagtaatgtc tgaacaatta aaaaacgctg gttgcgtgaa
     2341 agatagtttc ttagaaggta tcaccaaccg tgaacaagaa tttccaactg gattagaagt
     2401 aaatcaaatt gggtttgcta tcccacatac agattccgca catgtaaata gctctcaaat
     2461 ctgttttgcc tcattaaagg aaccactggt attttcagat atgacagata aatctcatga
     2521 aatacctgta cgtttagtct ttatgttggc aatgtcacaa cctcatgaac aaattgatac
     2581 actacaaaac ttagttagcc tatttcaaaa tgaagaaaaa gtaaatgaat tacttgcatg
     2641 taccacgaaa gaagcattta ttgagttagt acattctgca ggagtttatt aggaggaata
     2701 gagagatgga tattgtatta aatgcctttg aatggtttat tggattaggg tcaaacgtct
     2761 ttttaccact gattattttt gtaatcggga tattatttgg attaaaacct ggtaaagcat
     2821 ttgtttccgg cgttactgtt ggtatcggtt ctattggttt aggattagtt ttaagtttat
     2881 tatcagatgg tttaggaaca gcaattcaac aaatggggga acaatacggt ggtggcctga
     2941 atatcctaga tattggcgta ggtgttggtg gacctttggc ttactctaca tcattgggaa
     3001 ttttaatgat tccaatttca ttaattctta acttcatatt tgtggttttg ggttggacaa
     3061 aaacattgaa tgttgatatt tggaactttt ggttcgcaat tttcctaggt atgattactc
     3121 aatctgttac gggaaacttt tggtttggct taattggcgc gattgtcgca gtaattttac
     3181 aatggttctt agcagatcgt acacaaaaaa ctgttagcga atttttcggc tatccaggaa
     3241 tctctatcac acatatgatg ggattatcag gagtactatt tgccaaacca gtaaattggg
     3301 tttttgatcg tattcctgga tttaataaaa tagatgcaga tgcagaaaca ttaacaaaac
     3361 gtttcggtgt tttaggtgac acagttgtta ttggcctaat tatcggtatt gtagtgggta
     3421 ttatggcagg ctatgacgta gcaggaattg gaaacttagg aattatgact gcggcagtga
     3481 tgaagattat gcctaaaatg gtagcaatgt ttatggaagg tttaatgcca attgcagaag
     3541 cggcgaaaga atttacgaat aaaaagttaa atggtcgcca agtaaacatt ggaatggatg
     3601 cagcgttaac tgtgggtcat ccaactatta tgtcaacttc tctattgctt gtaccaatct
     3661 cattattgct agcactaatt cttccaggaa ataaagtatt accttttgga gatttagcat
     3721 tctttgcttt cgccatctgt ttaatgattc cttattttaa aggaaatatt gtgagatcat
     3781 tagtaggatg ttcgttgtat gttgttacaa cattatatat ggcaacatgg ttggcaccaa
     3841 ttatcactga tgtgtttaca ttagcaagtt tcgatgtggg gacagcagga ttagtaacta
     3901 tgttgttatg tggattatgg ccagtagggt tgtttgtttt attagcatct tactttggtg
     3961 taattggaat aggtggatta ggagttgttt tagtaggtgc ttctatctac atgaacaaag
     4021 tgaagaaagc ttaatcataa aattaaaata agaaagaaga gatcaatatg aaaaaattat
     4081 tagttatttg tggagcaggt catgctactt ctacaattgc agtagcaaaa ttatcaaaat
     4141 ggttggaaga agaaggatta acagatcaag tgaaaattta tcaatctaaa attgctgatg
     4201 agctaaataa aattgatgaa tatgatgctg tagtaagtac aacaattgtc cctgatgtaa
     4261 ttaaagctaa agtaacgaat ggcttgggct tattaacagg tattggtaca gatgccattt
     4321 atgcagatgt aaaagaaaga ttaggtgttt aatatgcgtt ttcatcatga cactttgact
     4381 attgaaacag tttcagggcg tccttcgtat catgatattc gaaaagaact tttagataca
     4441 gttgatacag caggtattga gaatggaatg ttagtaattt cgagcccgca tacaacttgc
     4501 tcactctttt ttgaagaaac gatgcatgac acaaactttt ttggtgatga ttatttacat
     4561 gtagacatca acaatgtaat ggaaacgatt attccaaaaa tgacgagtga aaatcaatac
     4621 aacagtccgg ggccaaaaca cattgatttt ggaacaagat tatctgatcc caattaccct
     4681 gcagaaaaat gggtcatgct aaataccgat gcacatttac gttcatctat ttatggaacc
     4741 aactcaatga ctttaattgt tcaagaaggt aaacttttat taggagaaat gggccgtgtc
     4801 tattttgtcg attgggatca actaagagag cgaactagaa caatcaatct catgattatg
     4861 ggagaataaa cgggggaata gagaatgaca attgctccat cattgttaaa tgcacctatc
     4921 gcagaagtta aagagttatt tgaaatctta aaagaaaaga atgttgatta tttgcatatt
     4981 gatgtaatgg atggctgttt tgtaccagat atggcttttg gaccaagtgt tattaaagat
     5041 attcgtccac taacagacgt tgtgtttgat gttcatttga tgattgatac accagaaaaa
     5101 attgtcacaa gatttgtaga agcaggagca gatattgtta ccttccacat tgaagctacc
     5161 aaacacgcaa tgaaggtcat tcagttagtc aaggaagcag gagcaaaagt agggattact
     5221 tttaatcctg caacaccagt cagttttatt gaaccagtat tatctttagt cgatcaagta
     5281 ttagtaatga caatcaatcc aggaacagag aataagcatt ttattcaaga gacagtagtt
     5341 aaaatcgaac agttagatgt aatacgcaaa caaaatgatt atacgtatga tattgaagta
     5401 gatggcaaga ttgataatca aacgattaaa gtttgttcta aagcaggggc ggatattttt
     5461 gtatcaggcg gtttcatctt caatgggaaa aataccccgc aagaacaaat tgataaacta
     5521 aatcaatcat tagaggaagt gaagtaaaag atcatgacca ataaagacca aaataaaaac
     5581 tatttagaag cgattatctt agaattacaa aataactcaa aacgtattaa ttctgtagag
     5641 ttagaacaat ttagtgagaa aattgttcaa gctaaacaca tctttctagc tggtgcagga
     5701 cgctctggaa ttgccatgca agcatttacg aatcgcttaa tgcatttagg tttttcagtc
     5761 agccttgtcg gtgaaattag ttcaccacat tcgcaacctg gagatttatt aattatctgt
     5821 tctggctcag gtgaaacagg tagtttaaaa aatttagcgg ccaaagcaaa tcaaagtggt
     5881 gtaagcattg ctttagttac catgaaaaaa gactcgtcga ttggtcaatt agcagattct
     5941 gttcttgtat taccaggtat taccaaagat gaaaatcaac gagaagaaga tactttttca
     6001 caacctatgg gttcaagttt tgaacaatta gcatttctca cctttgatag tttagtgtta
     6061 tctttaatgg ataaaacagg tgaaagctca gaaacgatgt ttgctcgaca tgcagatttt
     6121 gagtagtaga ttttaaagat aaaaaaccat tctctaaatg ctaattattc agcaaatatg
     6181 agaatggttt ttttatttga ttagacataa cttaataatt cagtagtttt gagcgtaagc
     6241 gtgtcataga atggtaccta aacacaaata gcccgatttg atacactcaa atcaggttat
     6301 ttgtggctta tattatttac agatttcttg tatctgctga ttccatggca aataagcgcg
     6361 tagcgcttca ggtgtcatcg aagacagatt gggaatctct gtaaaaagat gatttaaata
     6421 tttgcggatg tttaacccat tcgcaacagc tgtctggata atactcaata taattccatt
     6481 tgatctagcg ccttttaagc ttttagaaaa tagccagttt tttcgaccga tcactaactc
     6541 tttgatggca cgctctgctc ggttatttga aagttccaag cgtccatcaa gcaacacaat
     6601 ctgaagtccg tctttatgat tgactgcgta ttgaaccgcc tttccaagct gcgattttgg
     6661 caaataagca aaactctcac accaatgaaa aaattcagtc atcacaggct gcaacgtttc
     6721 cttcctcgct acaaaccttt cttctgcgct aagcttatta aaggtccgtt cgattcgaaa
     6781 catcttgtca cagaagtcta atcctatttt ggcatgactt tttggggacg gttgtttacc
     6841 caatgcttca aaaaactttc tgcgaacatg cgcccaacaa taaacattgt ttaccggcag
     6901 ctttccatag gccgcgtaac catcagtatg caagaaaccg ctaaatgatt ctaaaaaact
     6961 ttttggctca tcaacggaac gcgaatttgc gtgctcgtag agcacaactt gtttttcttc
     7021 gcttttacct gaagcatata accagtaaaa ggtcttttct ttatgagtat tcaatacccg
     7081 atagcttgtc tcatccgcgt gtaagacctc ctgattgctt aattcttgat gaaggcaatt
     7141 gtagattggc tctaaaacca tttcacttac cttgatatgc caattagtga tttttttacg
     7201 atcaagaggg aaaccaagtg catgccattc tttttcttgt cgatatgccg gcaccttttt
     7261 aacaaatttt tcccaaatac tctgtgtcac aattgaagag gaacctagac tattattgat
     7321 caacggttta ggaacaggcg cttttttgat ttttgtttct cctaatgctt cacattctct
     7381 gcaatgatag gcatgttggt agatgacttg tttttctata tgggcaggaa catacaatgg
     7441 ctcttctcta agccttgtcg caccgatatc atgtaaagta tgaccacagt cttcacacaa
     7501 acaatcggca ccttttaatt cataatgaat aggaacttca ggcagacctt ctaatgaaag
     7561 tgctttgagt cccttgcgtt ttctgcgttt aaaagaagat accgtaatgg gttcctggct
     7621 ttcttgtcca gtgtgctctg gttcattaaa agttgagtcg tctaataaat cgatttgccc
     7681 atctacgggt ggtgtttctt tttttcgtcc aaacaagcgt cgattcattt cagcaatttg
     7741 ttctctaaga agagtatttt cctgttgctg gatttcaagc aactgtgtta attgcttgat
     7801 ttgtacaaga agttcagatt ccatttttgt catttttaca ccaccattct agcgattttc
     7861 ttacatctat tataccattt tatgacaacg aaaaacagac aaaatccttg atttaacaag
     7921 gttttcgtct aatatatcgc accttttttc gtttctttta gcgtacattt ttcttcgatt
     7981 gaaaggccag tcagtaagac ttcttttctg gaacgcggcc attgaaggta cccactttca
     8041 aatcttttgt acattaatac aaatccattt tgatcctagt aaagagcctt gaagcgatct
     8101 ttcttcgtac cgcaaaataa gaaaagcgct tgatcgtaaa catcaaggtc atattcttct
     8161 ataacgaaag ctgctagtcc atcaattcct tttcgaagat ctgtttttcc acaaacgata
     8221 aaaatatgtt tcaatgcagt tgcatcaatg agcattggca ttcaactctt ttaacaaggt
     8281 atacaaaaga tatttatcca ttccattata aataaatatt tccttatctt ccgatttgat
     8341 tctgcaagct agttttggct tggtgtcaat ttgcgatttt tgagccgcac ttgaaaattg
     8401 aactggtaca atatcttttt tattcattcg tttttctcct tctatatttg atagtttaat
     8461 tatagaagaa agataatcgg cgtacgagat actatcctat gacacgctta catttaattt
     8521 aatattttgc ctcaaattag ccacactttt tatagaacta agaggaaaaa tgaagttttc
     8581 ttcctattaa tatagttgtt tgaaatctta aatatagcgt tttacgatgt aatgggaagt
     8641 atggtgaata aatcaactat gttcgtacga agcatttact caactaattt aatcgaatct
     8701 ttcaataaac aaatcaagaa atacagccac cgcaaggaac agttccaaaa tgaagagtcg
     8761 atggaacgtt tcttagtctc gtcttttgat acttacaacc aaaaattcct aggtcgcagt
     8821 cataaaggtt tccaacaggc cgaaggcgag ctcgaacaaa tgctgagtca accgatggag
     8881 aattagaaac aatctacagt agggaagaac cattgacaca aaattattga cgctcccaac
     8941 taaaaatgtc aaaataatga tgaaatcatt tagttcttat aaattagaaa agagaaaata
     9001 aatattccat atctacttta ttggatccgt aacatgacta aattctgaat actttttaaa
     9061 gcttatcatt tggtaaaact gaatataagt taattatata gactgaaaat tttgaatttt
     9121 cagaatagaa taacttaaaa gtactgacaa aattttttaa aggggcaata ttaatgttct
     9181 gagataatca aatcctaccg aaaatatcaa aaatccaatg tgacacaatc agattgtgtc
     9241 tcattcgagg gaatcacaca atcccacgtg gctctaggca gaattgaatt tttgcttggg
     9301 gctttttcct tatattgatt ttgaatgaga cttattatat gttataatgc aattaagtat
     9361 cattggagag ggcgaagaaa atgaagacgg tagaacctat tcgagacaaa aaaaagatcg
     9421 atgcgatgaa ggcaatcttg gcttcgggaa aatatggcca acgaaatttg gttctttttt
     9481 cgattgggat caacaccgcc tatcgcattt ctgatttgcg tcaattgaag ctggccgacg
     9541 tgctggaaat ttcacgcggt cgcgtggtgg tcaaagatcg attagcgatg aaggaacaaa
     9601 aaacagctaa acataattcg gtctatattt ccaacaaatt gcgaaaaacg attttggagt
     9661 acgttcaaca ggaatttcct gatcaactcc ttcagcaaga ttttgacggt tatttgttcc
     9721 ctagtcgaaa agggacgaat gaaccgctca accgccaaag tctgtggcga atcattcatg
     9781 atgctggcac ggcaatcgga ttgaaagaca ttggcccaca ttccatgcga aaaacgttcg
     9841 gttactttct ctataaacag gggaccaaaa cagaaatcat tcagtccttg ttgaaccatt
     9901 cttctcagcg cgaaacattg cggtatattg gtattacaca agaagacaaa gatacagctg
     9961 taaaaagctt agatttataa tataaaagtt aagtttaaac atggatagtt ttaaattagt
    10021 agattgagtg ttgggaggaa agaatgagta cattatatat tataggaaac ggttttgatt
    10081 taagtcatgg tttaaaaact agatacactg atttttcaaa atgggttgaa aaaagtcata
    10141 gtgaaatatt cgataaaata gacacaatga taaatgaaaa taatgaggtg agaagtacag
    10201 ctgatgataa gataggttgg tttaattttg aaagtagttt gcatgagtta attcaaagtc
    10261 cagtctttga agattatgta gaagagtcta aggattatct cataggttat ggacatgaag
    10321 attggtcaga ttctgcccat catgattttc aaaatatggt ttatgattat gttgtttctc
    10381 tagaagaatt acaacaactt ttcaaggaat ggatacgcaa agaaatacag ccgacaatag
    10441 aacataaaat tccaaaatac caattttcgt ccgatgtact attctttaca ttcaattata
    10501 cagatgtttt ggaaattcta tacaagcaac cgaaagaaaa catatatcat attcatggca
    10561 gttatgacga tataataatc ggccactccg agaattttga caactttata ggagat
//
LOCUS       DAPBBR010000081        10577 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPBBR010000081 DAPBBR010000000
VERSION     DAPBBR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.085"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            12..84
                     /locus_tag="RD488_002433"
     tRNA            12..84
                     /locus_tag="RD488_002433"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="RD488_002434"
     tRNA            88..160
                     /locus_tag="RD488_002434"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="RD488_002435"
     tRNA            168..249
                     /locus_tag="RD488_002435"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="RD488_002436"
     tRNA            267..339
                     /locus_tag="RD488_002436"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="RD488_002437"
     tRNA            351..422
                     /locus_tag="RD488_002437"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="RD488_002438"
     tRNA            439..524
                     /locus_tag="RD488_002438"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="RD488_002439"
     tRNA            535..608
                     /locus_tag="RD488_002439"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="RD488_002440"
     tRNA            618..691
                     /locus_tag="RD488_002440"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="RD488_002441"
     tRNA            711..783
                     /locus_tag="RD488_002441"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="RD488_002442"
     tRNA            811..884
                     /locus_tag="RD488_002442"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="RD488_002443"
     tRNA            898..971
                     /locus_tag="RD488_002443"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="RD488_002444"
     tRNA            995..1084
                     /locus_tag="RD488_002444"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="RD488_002445"
     tRNA            1097..1170
                     /locus_tag="RD488_002445"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="RD488_002446"
     tRNA            1189..1264
                     /locus_tag="RD488_002446"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="RD488_002447"
     tRNA            1266..1336
                     /locus_tag="RD488_002447"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="RD488_002448"
     tRNA            1350..1423
                     /locus_tag="RD488_002448"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="RD488_002449"
     tRNA            1448..1535
                     /locus_tag="RD488_002449"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="RD488_002450"
     tRNA            1557..1628
                     /locus_tag="RD488_002450"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="RD488_002451"
     tRNA            1651..1740
                     /locus_tag="RD488_002451"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="RD488_002452"
     tRNA            1753..1826
                     /locus_tag="RD488_002452"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="RD488_002453"
     tRNA            1845..1917
                     /locus_tag="RD488_002453"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="RD488_002454"
     tRNA            1921..1993
                     /locus_tag="RD488_002454"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="RD488_002455"
     tRNA            1998..2068
                     /locus_tag="RD488_002455"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="RD488_002456"
     tRNA            2081..2154
                     /locus_tag="RD488_002456"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="RD488_002457"
     tRNA            2166..2237
                     /locus_tag="RD488_002457"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="RD488_002458"
     CDS             2503..3696
                     /locus_tag="RD488_002458"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDT7658482.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="RD488_002459"
     CDS             3826..5298
                     /locus_tag="RD488_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7658483.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="RD488_002460"
     CDS             5381..6169
                     /locus_tag="RD488_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDT7658484.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="RD488_002461"
     CDS             complement(6236..6904)
                     /locus_tag="RD488_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDT7658485.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="RD488_002462"
     CDS             7019..8731
                     /locus_tag="RD488_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658486.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="RD488_002463"
     CDS             8734..10506
                     /locus_tag="RD488_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658487.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         3035 a         1926 c         2454 g         3162 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggcagaa
//
LOCUS       DAPBBR010000082        10492 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPBBR010000082 DAPBBR010000000
VERSION     DAPBBR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.086"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..360)
                     /locus_tag="RD488_002464"
     CDS             complement(<1..360)
                     /locus_tag="RD488_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDT7658488.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGI"
     gene            complement(712..1071)
                     /gene="rplT"
                     /locus_tag="RD488_002465"
     CDS             complement(712..1071)
                     /gene="rplT"
                     /locus_tag="RD488_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDT7658489.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="RD488_002466"
     CDS             complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="RD488_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDT7658490.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1396..1920)
                     /gene="infC"
                     /locus_tag="RD488_002467"
     CDS             complement(1396..1920)
                     /gene="infC"
                     /locus_tag="RD488_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDT7658491.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1964..2089)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2240..2872
                     /locus_tag="RD488_002468"
     CDS             2240..2872
                     /locus_tag="RD488_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7658492.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2874..3779)
                     /locus_tag="RD488_002469"
     CDS             complement(2874..3779)
                     /locus_tag="RD488_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7658493.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3864..4523)
                     /locus_tag="RD488_002470"
     CDS             complement(3864..4523)
                     /locus_tag="RD488_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7658494.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4839..5783
                     /gene="mvk"
                     /locus_tag="RD488_002471"
     CDS             4839..5783
                     /gene="mvk"
                     /locus_tag="RD488_002471"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDT7658495.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5776..6753
                     /gene="mvaD"
                     /locus_tag="RD488_002472"
     CDS             5776..6753
                     /gene="mvaD"
                     /locus_tag="RD488_002472"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDT7658496.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6766..7851
                     /locus_tag="RD488_002473"
     CDS             6766..7851
                     /locus_tag="RD488_002473"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDT7658497.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7848..8912
                     /locus_tag="RD488_002474"
     CDS             7848..8912
                     /locus_tag="RD488_002474"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDT7658498.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9161..9964)
                     /locus_tag="RD488_002475"
     CDS             complement(9161..9964)
                     /locus_tag="RD488_002475"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HDT7658499.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9984..10289)
                     /gene="kduI"
                     /locus_tag="RD488_002476"
                     /pseudo
     CDS             complement(9984..10289)
                     /gene="kduI"
                     /locus_tag="RD488_002476"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(10271..>10492)
                     /locus_tag="RD488_002477"
     CDS             complement(10271..>10492)
                     /locus_tag="RD488_002477"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HDT7658500.1"
                     /translation="WALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLIV
                     IIIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         3103 a         2219 c         2008 g         3162 t
ORIGIN      
        1 aatacctaat gacatcaaga tcggcaacac aataactgca atagaaatca ctggtccgat
       61 tcctgtcatc gacatgaata taacagcggt tacaatacat agtaagctca tcgtgattct
      121 tggcttgtcc cctccaagtt caactacctt tcgaatcagg gtagctgcga ttccgctatc
      181 tactagaaca cgcccgaaaa aggcaccaaa gaagacattt accaagatcg atttggcgta
      241 ctcagctggc cccgtcgtat agatatgcgt caacacatca attactcctt gcccttccat
      301 cgccgagttt ggtgaaaacg tgtttccgac tagcgctaat cccatccata cagtagccat
      361 gatgacaaaa gccgaccatc aagttgtagc cttttacaca gtaccagacc atgaaaaaga
      421 atgagataac taacaaaata ccaataataa tatcactcat gttattcctc cgtccatttt
      481 gtttttctga taagcaaact aatatatcag tcaaactcat tctaacttat gtagttagcg
      541 ctttcattaa aggatgacca taaatgttca gttttcaatt aaaaaacctt aattatgtta
      601 ttttagactt atacgttatt gtcctgtttc atttgatgga ggattgtaaa taaaaaaaga
      661 ggaaagaaca taacttttcg ttatcttctt tcctctttat aattgtttag cttatttagc
      721 caaagcttct tttgcttggt cagccaatgc agtaaatgct gctgcatcgt taacagccaa
      781 gtcagctaac attttacggt tgatgtcgat ttcagcaact ttcaaaccgt gcattaattt
      841 tgagtagctc aagccattca tacgagctgc tgcgttgata cgagcaatcc acaatttacg
      901 gaagtcgcgt ttcttttgac gacgatcgcg atatgcgtag ttgtatgaat tcattacttg
      961 ttcttttgct gttttaaata aagtgtgttt tgaaccgtag taaccttttg ctaattttag
     1021 cactctttta cgacgtttac gagttactgt tccaccttta acacgtgcca tgtataattc
     1081 ctcctaataa aaataaatct tcagattctg ttatttgtac ttcttatttc atttttgcta
     1141 gttgttggcg aatacgtttg aagtcgccac tagaaaccat gcttgcttta cgcaattgac
     1201 ggcgttgttt ttttgttttg ccgtggaaac ggtgacttgt aaacgcgcgg aagcgtttca
     1261 atccgccttt accagtacgt ttgaaacgtt ttgctgatcc gcggtgtgtt ttttgttttg
     1321 gcatgactat atttcctcct caaaatcttt cgttatccga ctatcggctg tccaacagcc
     1381 agttagtcat tcaaattact tactgtcgtt tttcggtgcc agcgtcaaga acatgctgcg
     1441 tccgtccatt ttcgcttttt gttccactgt tgcaatatcc gcagtttctt cagctaagcg
     1501 attcaagact ttttgaccaa tttctttatg ggtaatggca cggcctttga aacggataga
     1561 agctttcact ttatcgccct tttccaagaa cttacgtgca ttacgaagtt ttgtattgaa
     1621 gtcattcaag tcgatcgtag gacttaagcg aacttctttt acattgatca ctttttgttt
     1681 tttacgcgct tcgcggtctt tcttttgttg ttcgaaacgg tatttaccgt agtccatgat
     1741 tcgcgcaact ggtggtttcg caccaggggc aactaacaca agatccaagt ttgcttgttc
     1801 tgcaatattc aatgcttctg cttttgtctt aactcctaat tgctcaccat ctgaaccgat
     1861 caatcgtaac tctcgtgcac gaatgccgtc gttaaccatc atatcctttg ctatggtcat
     1921 tcacctccaa atattatgag agaaagaaaa gcttaccgaa taaacggcaa taaaaaaacg
     1981 agttctctta cagaacccgc gcgtacttca cctaatagaa ccagtgaaaa ctatctagcc
     2041 cagtgacatt atcaactaag gcgagaagcg ggtgcttctg cttttatttc tcaaccatta
     2101 tagtatagca aaaactaatc tttttgtcaa tgtttttcat acagtttgtc ttccttttct
     2161 gaaaatgatt agattagcag gctttctagc agtgattccc gcttctttgc tatactaaag
     2221 aaaaacgagg tgaacccaca tgaaaaaaat cgaacctatt ccaccttctc ttcctcttct
     2281 tacaaaggga gagttttatt tagaagatga ggagatcttc tctggtcttc tgatcaacgg
     2341 aggtaaccaa agctatctcg atgccaaaaa tatggtatta agagagagtc atatccaaaa
     2401 acttacgatg caaaaaacag gtttacgtca ttttgaatgc agtaatgtca tttttgaaaa
     2461 atgtgatttt tccaatctgg agtggattgg tggcagtttc caccaagtcg tgtttcatca
     2521 atgtaaatta acaggtacga attttgccga aagttatctt cgagactgta ctttcactga
     2581 ttgtattgct tcgatggctt cctttagtag tacaaacttg aaagctgtct ccttcgatca
     2641 ttgtcaatta gaagacagcg aattttatga ggtcacttgg aaaaaccttt ttttgtctga
     2701 caatcagtta accggttcga actggtttcg aacttctctg aagggattag actttacgac
     2761 taatttcttc acaacaatcg ctttatctca agattctttg gcgggactaa tcgtcaatca
     2821 agagcaagca cttgtgatcg cccaagccct tggtttgcag atcaaagact agatcaacga
     2881 atccgccgcc acagtgcaat aagcatccaa atagataaga ccaaactgat gatcaaggcg
     2941 atttcccatc cgaaaacgga atgggtaaag ggtaactgga gattcattcc gaagaatcct
     3001 gtcacaatag ttggaacggt caagatcagc gaccagaccg tcaaaaattt catcgtgtca
     3061 ttcaagttgt tattcagcaa attattataa gtgccagaga gctggtctaa aatctgcgaa
     3121 gctaagttcg tcatttcaac tgcttgtcgt gcttcgatca gtgcatcgtc caactcttct
     3181 ttttcctttt ctgacaactt gcgataaata gccagtgcct tgatttgttc taaaagtact
     3241 acattttgtt ttgttcctgt aactaagtaa accaaaccga tctctaaatc tgaaagttgc
     3301 agcagattct tgttcgttgt tttttctctt aatttcagat taagccgctg acgttcacta
     3361 ttcacttcct cgattaaagg aaaaaaggaa tcagaaatca aaaacaatgt acgaaacaat
     3421 aaactgtata cactcatgtc tggcatccgt tccaaaagcg atcgaattag tcgaatcacg
     3481 tactcggtat tcggcgtggt aaatgtaaac aaaccgtctt cttttaaaat aaaagcgata
     3541 ggactagttt cataatgatt atcgactttt tgctggtgcg gaacatttga tacaagcagt
     3601 aacgcttcat caaaagaatc gtactctacg cgcgcccgtt catttttatc tagagaataa
     3661 gtcagcatct cgtcactaat gccatattct tcttttaagt ttttaacagc tagcacatcg
     3721 ttttgctgta cattgatcca aaaattacgg tcttgattaa aatagtgttt ttcccgcata
     3781 ctctatcctc ctgacatttg tttccagtat aaagaaaaaa gtcgctcaaa taaaggttta
     3841 ccctttattt gagcaactgt aaatcaaatg gatactttgg tttggcgaat ctctgctaat
     3901 ttttcttcga tcattttcaa gacttcttct tttgcttgag gatcttccac aaaattatag
     3961 cggtctccat cgatttggat ttttggactt tctttgtatt cttcatacca ttgatcataa
     4021 cgtctgttca attctttgta ataatcgtat agacttgggt caaaggacaa ttgttcatac
     4081 gaacgaccac gtttttcgat acgctctaac atcgtatcaa aagatacacg aatatgaact
     4141 aataaatccg gatgtttttt atgggcagca tagggaagtt cttccatcat gttttccagc
     4201 agttcatcat acacacaaac ttctgtttct gttgctcttc ctagatctgc atttagatgg
     4261 aaaagcagtg aatcttcata aatcgaacgg tccaatacat tattgtcatc tttcattgct
     4321 tgtttgatgc ttgcaaaacg tttattcaaa aaataaattt gcagcaaaaa agcatactgt
     4381 tcagggtttg cataaaataa gggcaagact tcattatcat caatcgattc ataaaatgcc
     4441 tgactatcaa agtgttcagc catcatttct gttaaacttg attttccggc accaattgta
     4501 cctgctaaaa cgatcacgct catttacctc cagctcactt catcactaaa tattgtgttt
     4561 aactccaacc ttttttaaat atacccccaa tatctagtag tgtcaattgt attttttcta
     4621 gtcaaagaag aaaaaaagtc aaaaaattct taagaaaaaa gtgttttttc tttagaaaac
     4681 gtattcttag ttttacttct gagatggttt tagtaaaata aaggaggaat gttttttgag
     4741 acccttagtg gacaaaaaaa ttcgtgaagc agcgcaactc gttttgggcg ctttattttt
     4801 tgcttaaaaa tcacttttac gtgagaagga gttagattat ggcaaactat ggccaaggag
     4861 aatcaagcgg aaagatcata ttgatgggcg agcacgcggt tgtttatgga gaaccagcga
     4921 ttgcctttcc tttctatgca acaaaagtca ccgcattcct tgaagagctg gatgcaatgg
     4981 acgatcaact ggtttcttcc tactattcag gaaatttagc cgaagctcct catgcattaa
     5041 aaaatatcaa aaaattattc attcacttaa aaaaacagca tgacatccaa aaaaacttgc
     5101 aactgaccat tgaaagcacg attcctgctg aacgtggaat gggatcaagc gctgcagtcg
     5161 ccacagcagt cactcgtgct ttttatgatt acttagcatt tcctttgtct cgtgaaatac
     5221 tattagaaaa tgtccagctt tcggaaaaaa tcgcccacgg taatcctagt ggaatcgatg
     5281 cagccgctac tagcagcttg cagccgattt attttacaaa agggcatcct tttgactact
     5341 tttctttgaa catcgatgct tttttgattg tcgctgatac aggaatcaaa ggacaaacaa
     5401 gagaagccgt caaagatgtc gctcacctct ttgaaaccca gcctcatgaa actggacaaa
     5461 tgatccaaaa attaggatac ttgacgaagc aagcaaaaca agcaatcatt gagaattcac
     5521 cagaaacgtt ggcacagaca atggatgaat cacagtcact tctggaaaag ctgacaatca
     5581 gcaatgattt tcttaatcta ttgatccaaa cagcaaaaga taccggggca ttgggtgcca
     5641 aattaactgg cggtggacgc ggtggctgta tgattgcatt agcacaaaca aaaacaaaag
     5701 cccaagaaat cagtcaagca cttgaagatg cgggtgctgc tgaaacttgg atacaaggat
     5761 taggagtaca tacctatgtt taaaggcaaa gcacgcgcat ataccaacat tgctctaatc
     5821 aaatattggg gtaagaaaaa tgaagaactc atccttccaa tgaacaacag cctttcgtta
     5881 acattggatg cattttatac agagacagaa gtcatctttt ctgatagcta tatggtagat
     5941 gaattttatc tagatggcac cttacaagac gaaaaagcaa caaaaaaagt cagtcagttt
     6001 cttgaccttt ttcgtaaaga agccggcctc tcactaaaag cttcagtaat cagtcagaat
     6061 ttcgttccta ccgcagctgg attagcctcc tctgccagcg ggctagctgc tttagcagga
     6121 gcttgcaata ctgctcttaa gcttggatta gacgatctct ctctttcaag atttgctcga
     6181 cgcgggtctg gttcagcttg ccgaagtatt ttcggtggtt tcgttgaatg ggaaaaaggc
     6241 catgacgact taagttctta cgctaagcca gtcccttccg attctttcga agacgattta
     6301 gcaatggttt tcgttttgat caacgaccag aaaaaagaag tgtccagcag aaatgggatg
     6361 cgtcgaacag tcgaaacatc cagtttttat caaggctggt tagattccgt tgaaggggat
     6421 ctatatcaat tgaaacaagc aatcaaaaca aaagatttcc aacttctcgg agaaacgatg
     6481 gaaagaaacg gactaaaaat gcatggaacg actttagctg cccagcctcc attcacttac
     6541 tggtctcctg acagcttaaa agcgatggat gcggtgcggc aattgagaaa aaaaggcatt
     6601 ccatgctact ttacgatgga tgctggccct aatgtcaaag ttttagtgga aaacagccat
     6661 ttatctgagg tacaagaaac atttaccaaa ttatttagca aagaacaagt aattactgcc
     6721 catgctggtc caggaattgc gattattgaa taaagggaga tttttatgat tgaagtatct
     6781 gcaccaggca aactctatat tgccggagaa tatgcagttg ttgaaacagg acatccagca
     6841 gttatcgctg cagtcgatca attcgtaaca gtcactgtag aatccgcacg aaaagtcgga
     6901 agtatccaat ctgcacaata tagtgggatg cctgtacgtt ggacaagacg caacggagaa
     6961 ttagttttag atattcggga aaatcctttt cattatatcc ttgctgctat tcgtttgact
     7021 gaaaagtatg cacaagaaaa aaacattctt ttatcctttt atgatctgaa agtaacaagt
     7081 gagttagaca gttcaaatgg ccggaaatat ggattgggtt ctagcggtgc cgtgaccgtt
     7141 gcaacggtca aagccttgaa tgttttttac gcgttgaatt tatctcaatt ggagattttc
     7201 aagattgcag cactagccaa tttagcagtt caagataatg gttcctgcgg cgacatcgct
     7261 gctagctgtt atggtggctg gatcgctttc tcaaccttcg accatccttg gctccaagaa
     7321 caagaaactc agcattctat cagtgagtta cttgccctgg attggccagg tctatccatt
     7381 gagccattga ttgctcctga agatttacgt ttattgattg gttggacggg tagccctgcc
     7441 tctacttctg atttggtcga tcaagttcac cgttcgagag aagacaaaat ggtggcttat
     7501 cagcttttct taaaaaacag tacagaatgt gtcaacgaaa tgatcaaagg gtttaaagaa
     7561 aataatgtaa cgttgatcca acagatgatt cgaaaaaacc gacaattact gcatgattta
     7621 tctgcaatca ctggggtcgt catcgaaacg cctgctttga acaaattgtg taatttagct
     7681 gaacagtatg aaggagccgc aaaatcttct ggtgcaggtg gtggcgattg cggaatcgta
     7741 attgttgacc agaaatctgg catccttcct ttaatgagtg catgggaaaa agcagaaatc
     7801 actccactgc cgttacatgt ctatagcgat caaagaaagg aaaaccgatg aatcgaaaag
     7861 acgaacatgt ttcactagct aaagcctttc atgataaaca aaaaaacgaa tttgacttcg
     7921 tacggatcat ccataaccct ttgccgcaaa tagcagtttc tgatgtcgat ctaagtacac
     7981 aggcagttgg gtttacacta agcagcccat tttatatcaa tgcgatgact ggcggaagcg
     8041 aaaaaacaaa aaaaatcaac caagatcttg caatcgtcgc aagagaagca gatttgatga
     8101 ttgccactgg ttcagtcagc gctgccttga aagacccttc tttagccgat acttatacga
     8161 ttatgcgaca agaatatcct cacgggaaaa tcattgccaa catcggtgca gggacttctg
     8221 tcgaaagagc ccaagaagct atccgattgt ttcacgcaga tgccttacag attcatttga
     8281 atgcacctca agagttggtt atgcctgagg gagaccgtga ttttaccaat tggaaagtac
     8341 ttattcaaga gactcaaaca gccattgacg tccccctcat cgtaaaagaa gtcggttttg
     8401 gcatgacaag agaaacgctc aatgatctag ctgctttagg agttcataca gttgatatca
     8461 gcggtcgaag cggaacaagc ttcacccaga tcgaaaacgc ccgtcgctcc aagcgggaac
     8521 tgagttattt agctgactgg gggcaatcga cagtctcttc attgcttgaa gcaaatgaag
     8581 cagacacttc tatggaaatc ctagcctccg gaggtatccg caatgcctat gacatattta
     8641 aagccctttg tctcggcgca aatgcagtgg gtacttcagg aaccgtactg acgcatctga
     8701 tgaatcacgg cgtagaagaa actattatac tgatgaagca atggcaagaa gagcttcgtc
     8761 tgctttatac tatggtcggc gcaacgaata ccgcggccct acaccaacaa tcactgatct
     8821 tttccggacc agtgaaggat tggtgcgaag caagagggat cgacttagtg aagtatggaa
     8881 gacgcacaga aaagagcgtg ggacaaaagt aaagaacact tttatcccac gctctaaaca
     8941 cgtataaacg gcggaagcaa aagcaactcc ttcggaaata agctgaaatt cacaaaaatt
     9001 tgaaaagcaa ttttcgtgaa ttccttctta tttcttggag ttaaacgctt ctgtcccagc
     9061 ctcttttttc gaataaatga tgtttaatca gctgtccttc ggtattcgtt caagccgctg
     9121 atttcacaac ctctccacta aacggtgtac taaagctctt ttaaggttgt tttccgatat
     9181 aggcaagtat gcctccgtcc acatacaaga catggccgtt aacgaaatca gatgcgctag
     9241 aagccaagaa gacagatggt ccagccaaat cgattggctc gccccagcgt gctgctggcg
     9301 tacgtccaac gataaattga tcgaatggat gacgttcacc gttttcttgt gtttcgcgta
     9361 atggagcagt ttgcggtgta gcaatataac ctggtccaat tccattacat tggatattgt
     9421 attgaccgta ttcagaagcg atgtttttcg tcagcatttt taatccgcct tttgccgcag
     9481 cataagcact gaccgtttcg cgtcctaatt cactcatcat ggagcagata ttgatgattt
     9541 taccgccgcc tttttcgatc atatcccgaa taactgcttt tgaaacgatg aatggggcat
     9601 ttaaatccac gtcgattact tggcggaagt ctgccgcatc catttcgatc atcggtgtcc
     9661 gtttgatgat ccctgcattg ttgactagaa tatcaactga acctacatct tctttgatct
     9721 gttgaaccat cgcttgaacc gcttcttcat cggtcacatc gcagacataa ccttttgcat
     9781 cgatgcctgc ttctttataa tgcgctatac cttcatcaac tgattcttga ttcaagttat
     9841 taaatacgat ttttgctcct gctgtagcta aagagcgtgc aatctcaaat ccaataccat
     9901 agacagcacc ggtgactaat gctacttttc catctaaacg aaacatatcc atactaaatt
     9961 ccatcatttt ctctccctta tgcttatttt aattgatcca tttgcaccat atccatgtct
    10021 gtataggtga tattttctcc gcacattgcc cagatgaatg agtaattgct tgtacctaca
    10081 cctgaatgga tcgaccagct tggcgaaata atggcttgtt cattgtctac gactaaatgt
    10141 tttgtttcat ctggtttgcc catcatatgg aacacacgtg tatcttcatt ggcataatca
    10201 aaatagacat aagcttccat acgacgttca tgtgtatgac aaggcatcgt attccaagca
    10261 cttcctggtt ctaaaatcgt ataacccatt tataaatgac agctatcgct gaagcttcta
    10321 ctgctgtaaa tatccccgtc aagataccac cgataatgat gacaatcaat agaaggctag
    10381 gaatcgcctc ttttattatt tttccagcat gagccatctg tcctttttcg acaacagggt
    10441 atttattctt tttagcaacg atgaatgcta ctagcatgat tcctagcgcc ca
//
LOCUS       DAPBBR010000083        10342 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPBBR010000083 DAPBBR010000000
VERSION     DAPBBR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.087"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1..656)
                     /locus_tag="RD488_002478"
                     /pseudo
     CDS             complement(1..656)
                     /locus_tag="RD488_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(661..1428)
                     /locus_tag="RD488_002479"
     CDS             complement(661..1428)
                     /locus_tag="RD488_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7658501.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1916..2341
                     /gene="lacA"
                     /locus_tag="RD488_002480"
     CDS             1916..2341
                     /gene="lacA"
                     /locus_tag="RD488_002480"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HDT7658502.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2358..2873
                     /gene="lacB"
                     /locus_tag="RD488_002481"
     CDS             2358..2873
                     /gene="lacB"
                     /locus_tag="RD488_002481"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HDT7658503.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2884..3816
                     /gene="lacC"
                     /locus_tag="RD488_002482"
     CDS             2884..3816
                     /gene="lacC"
                     /locus_tag="RD488_002482"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HDT7658504.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3819..4799
                     /gene="lacD"
                     /locus_tag="RD488_002483"
     CDS             3819..4799
                     /gene="lacD"
                     /locus_tag="RD488_002483"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7658505.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4827..5144
                     /locus_tag="RD488_002484"
     CDS             4827..5144
                     /locus_tag="RD488_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7658506.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5144..6850
                     /locus_tag="RD488_002485"
     CDS             5144..6850
                     /locus_tag="RD488_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7658507.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            6992..8398
                     /gene="lacG"
                     /locus_tag="RD488_002486"
     CDS             6992..8398
                     /gene="lacG"
                     /locus_tag="RD488_002486"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDT7658508.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8421..8693
                     /locus_tag="RD488_002487"
     CDS             8421..8693
                     /locus_tag="RD488_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HDT7658509.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8714..9613
                     /locus_tag="RD488_002488"
     CDS             8714..9613
                     /locus_tag="RD488_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDT7658510.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
     gene            complement(10085..>10342)
                     /locus_tag="RD488_002489"
     CDS             complement(10085..>10342)
                     /locus_tag="RD488_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HDT7658511.1"
                     /translation="HKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNW
                     WNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT         3244 a         1763 c         2076 g         3259 t
ORIGIN      
        1 tttatgacga cttttggaag taaaaatcca tccattatct ttataatcag gattgaatct
       61 tatatgttgg tgatttaact caatttcctc tttaagaatt tctatagccc ttttagataa
      121 ttggacattt tggtaacttt gtaagttttt tacattacct tcatagctat tttctgcagc
      181 tcctccgtga gtggactgac taatgatgat attttgcttt tcaaaatatt gataggcacc
      241 aatattttgg agttttcgac tctgtaagtc aacagggcca ttagttagaa tacctattgg
      301 gatgcggttt ttatgtagag ccagtagtag ttgatgtatc tcaggaatca tcgtaatctg
      361 atcgagttca tattcatagt cagcttggaa gtctagagct tctgtcctag aaatactatc
      421 gatgccaaat tcttccatag tcttctgaca gcgaaaaatt ctaagctgct caatactgat
      481 gagtttttcg tgtatttagg aaaagcaaca tcagaccaac atctgaaacg tttgtaaatg
      541 ttatctattt gttggatatc aatcgttgga aaacatttct caacgctact tttaaagggg
      601 agttgatggt cataaagagt gtcatcaagg tcaaaaacaa tatttttata agtcataatt
      661 ctagtccgct tttaaaatag tagtgtactg gctaaattcc tctaagtgtt gagggctaat
      721 ctggttatct gtaatgatgg tatcgagttg atctagatta tagaagttaa agaaatcgta
      781 tcgatcgaat ttagtactgt ctactaataa gaatttttct acagcattgt ttagggcaag
      841 ttgttgaatc acaccttcct tgtcactata tgtagcaata gaattatggg taacagcatt
      901 tgcactaaca aaagctttgg caaatctaat tgcttttaaa tttgtcgaag ccattgaacc
      961 tacaaaagct ccagttattt ctctatattc accgccaaga agcaataaat caatggtttc
     1021 gctatcattt agaatcaaga acacagggag actatttgta atgacacgaa ttttataacc
     1081 tttacgacct ttcaattcta atgccagttg ttcaagtgta gttccgggtc caataaaaat
     1141 agtatcgcca tctttgatta aagagcaggc ttttttagca atgtcaattt tttcttttgt
     1201 atttagactt ttcttctcga tatgtgtctt ttcaagtggc tttttagagg aaagtaattg
     1261 tgcaccacca tgagtacgtg ttaaaagtcc atcagcttct agagcatcaa ggtctctacg
     1321 ggctgtcata tcggaaatat ctagttcatc tattatttct tttatggtta tggtcccatc
     1381 aatctttaac atatctaaaa ttttttctaa tcgtcgtttt ttgttcatat gaagaccctt
     1441 ctttcataaa gtaatttttt tccaaagata attctctttt aattgtatca taaaagacaa
     1501 tattttcaag gtaaaacaaa caatttcaaa caaaaacaaa tgttagatga tgaaataaga
     1561 acagtggatt gacgtatatt agcttaggtc agattttgta taagacgaaa ataaagtagg
     1621 acctcttaat cagtaagtta tagaaagtaa aagacttttg taatacttga atagatattt
     1681 cacgtccatt ttgtgatgga ttaaatgaac aaaaatgaac aataatttaa cggtgttatc
     1741 tattttttaa aaaaacaaat aaaaaaacaa aaaataaaca aaaaagtgtt gctttttgtt
     1801 tgaatgcttg atattatata aacaaagaaa tgatgaaaac gttttttcga acattttgca
     1861 aaatgttttc tacttctacg tagcatttct ttctaaaatt taggaggtgg tcaaaatggc
     1921 tattgttgtt ggtgcagatc tcaaaggtac gagattaaaa gatgttgtga aaaattttct
     1981 tgtagaagaa ggttttgagg taattgatgt gactaaggac ggacaagatt ttgttgatgt
     2041 taccttggca gttgcctctg aagtaaataa agatgagcaa aacttaggta ttgtaattga
     2101 tgcttatgga gctggtccat tcatggtagc aactaaaatt aaaggtatgg ttgcagcaga
     2161 agtttcagat gaacgctcag cttatatgac acgtggacat aacaattcac gaatgattac
     2221 ggttggcgct gaaatcgtcg gtgatgagct tgctaaaaac atcgctaaag gtttcgtcaa
     2281 tggtaaatat gatggcggac gtcatcaaat ccgagtagat atgcttaaca aaatgtgtta
     2341 aggaaaggag ttaaggaatg agaatcgcaa ttggatgtga ccacattgtc acagatgaaa
     2401 aaatggcagt atcagaattc ttgaaatcaa aaggacatga ggtccttgat ttcgggacat
     2461 atgaccacgc acgtactcac taccctatct atggtaaaaa agtcggtgaa gcagtagtaa
     2521 gtggtcaagc agacttggga gtatgtatct gtggtacagg tgtcggcatt aacaatgcag
     2581 tcaataaagt tccaggtgtt cgctcagcgt tggttcgtga tatgacatca gctatatatg
     2641 caaaagaaga gttaaatgcg aatgttatcg gtttcggtgg aaagattact ggtggtcttc
     2701 ttatgaatga catcattgaa gctttcattg aagctgagta caaaccaaca gaagaaaata
     2761 aaaaattgat tgcaaaaatc gaacacgttg aaacacataa tgcacatcaa gcagatgaag
     2821 atttctttac agaattcctt gaaagatggg accgtggtga ctaccacgat taaggtataa
     2881 caaatgattc tgacagtcac actaaatcct tcagtagaca tctcttatcc tctagaaaca
     2941 ttgaaaattg atacagtgaa tagggtgaaa gatgttagta agacagctgg tggaaaaggc
     3001 ttaaatgtta ctagagtctt gtatgaatct ggtgataaag ttactgctac aggtttctta
     3061 ggtggtaaaa ttggtgaatt tattgaaagc gaattagaac aatctcctgt tagtccagct
     3121 ttttataaaa tctcaggaaa cactagaaac tgtattgcta tcttacacga gggtaaccaa
     3181 acagaaattt tggaacaagg accaacagtt tctcatgaag aagcagaagg ttttcttgac
     3241 cactatagca atcttattaa acaatcagaa gttgtgacaa tttcaggaag tttaccttca
     3301 ggacttccca acgattatta tgaaaaactt atccaacttg cttcggatga aggagtagca
     3361 gtcgttttgg attgttcagg tgcacctctt gaaacagttc taaaatcgtc ggctaaacct
     3421 actgccatca aacctaataa tgaggaactt tcacagttgc ttggaaaaga agtaacaaaa
     3481 gatattgaag aactcaaaga cgttcttaaa gagtcacttt ttagtggtat cgaatggata
     3541 gtggtctcat taggtcgaaa cggtgccttt gcaaaacatg gtgatgtttt ctataaggta
     3601 gatattcctg atatcccagt tgttaatcca gtcggatcag gggactcaac ggtagctggt
     3661 attgcatcag ctttaaatag taaaaaaagt gacgctgact tattaaaaca tgcgatgaca
     3721 ttgggtatgt taaatgctca agaaacaatg acagggcatg tgaatatgac taattacgaa
     3781 acactaaact cacaaattgg agtaaaagag gtataaaaat ggtacttaca gaacagaaac
     3841 gcaaatcttt ggaaaaaatt tcagataaaa acggtgttat ctcagctttg gcatttgacc
     3901 aacgtggtgc tttgaaacgt ttgatggcac agtatcaaga tacagaacca actgtagctc
     3961 aaatggaaga actaaaggtt ttggttgctg atgaacttac aaaatacgct tcttcaatgt
     4021 tgcttgaccc tgaatatgga cttccagcaa caaaagcatt ggataaagaa gcaggtcttc
     4081 ttcttgccta tgaaaaaaca ggttatgata catcaagtac aaaacgtttg cctgactgct
     4141 tggatgtttg gtctgcaaaa cgtatcaaag agcaaggcgc tgatgccgtt aagttcttgc
     4201 tttactatga tgtagacagc tcagatgaac ttaaccaaca aaaacaagct tatattgaac
     4261 gtgttggttc tgaatgtgtc gctgaagata ttcctttctt cttggaaatc cttgcttatg
     4321 atgaagaaat ctcagatgca ggttctgttg aatatgcaaa agtgaaacct cgcaaagtca
     4381 ttgaagcgat gaaagttttc tctgatccac gctttaacat tgatgttctt aaagtagaag
     4441 taccagttaa cgttaaatat gtcgaaggtt ttgctgatgg tgaagtggtt tacagtaaag
     4501 ctgaagctgc tgacttcttt aaagcacaag aagaagcgac taaccttcca tacatctacc
     4561 taagtgcagg tgtatctgct aaattgttcc aagaaacatt gcaatttgct cacgactcag
     4621 gtgccaagtt taatggtgtg ctttgtggac gtgctacttg ggcaggatct gtagaacctt
     4681 acatcaaaga aggtgaaaaa gcagcacgtg aatggttgcg tactactgga ttcgaaaata
     4741 ttgatgaact taacaaagtt cttgttaaaa cagctagtcc atggactgat aaagtatagt
     4801 aaaaacataa aacggaggat attgttatga acagagaaga gatgactctc ttagggtttg
     4861 aaattgttgc ttatgctgga gatgctcgct ctaaactttt agaagcgctt aaagcggctg
     4921 aaaatggtga tttcgctaag gcagatagtc ttgtagtaga agcaggaagc tgtattgcag
     4981 aggctcacaa ttctcagaca gctatgttgg ctcgagaagc ttctggggag gaacttccat
     5041 acagcgttac catgatgcat ggtcaggacc acttaatgac tactgtctta ttaaaagatg
     5101 tgattcatca cctcatcgaa ctttataaaa gaggagcaaa ataatgcata aactcattga
     5161 acttattgag aaagggaaac cgttctttga gaaaatctct cgaaacatct atcttcgtgc
     5221 tattcgtgat ggatttatcg ctggtatgcc agtcatcctt ttctcatcta tctttatcct
     5281 tattgcctat gtcccaaatg cttggggatt ccactggtca aaagacattg agaccttctt
     5341 gatgactcct tatagctatt cgatgggtat cctagcattc tttgttggtg gtactaccgc
     5401 taaagctttg acggactcaa tgaaccgtga cctacctgcg accaatcaga ttaacttctt
     5461 atctacgatg ctagcgtcta tggtagggtt ccttttgatg gcagctgagc ctgcaaaaga
     5521 aggaggcttc ttgacagcct tcacgggaac aaaaggtctt ttgacagcat ttattgcagc
     5581 ctttgtgaca gttaatgttt acaaggtctg tgtgaaaaat aatgttacta ttcgtatgcc
     5641 tgaagaggtt ccaccaaata tctctcaagt atttaaagac ttgattccat tcactgtagc
     5701 ggttgttctc ctttatggat ttgaactcat tgttaaggga actcttggtg taaccgttgc
     5761 agaatcaatc ggtaccgttc ttgctcctct cttctcagct gcagatggtt accttggaat
     5821 tacacttatc tttggtgctt atgccttctt ctggtttgtt ggtatccacg gtccttcaat
     5881 tgtcgaacca gcaatcgctg ctatcactta tgccaatatc gatgccaact tgcatcttat
     5941 ccaagctgga caacatgcag ataaagttat cacttctggt actcaaatgt ttattgttac
     6001 catgggtgga acaggagcta cattgattgt tccattcttg ttcatgtgga tttgtaaatc
     6061 agaacgtaac cgtgccatcg gacgtgcctc agttgttcca acattctttg gggttaatga
     6121 gccaatctta tttggtgcac caatcgtatt gaatccgatt ttctttgtac cgttcatttt
     6181 cgctccgatt gtcaacgttt ggatctttaa attctttgtt gacacattga acatgaactc
     6241 attctctgcc aaccttccat gggttactcc tggtccgttg ggaattgtac tcggtactaa
     6301 cttccaagtt ctatcattta tcttagccgg actcttggta gttgttgata ctatcattta
     6361 ttacccattt gttaaggtat acgatgaaca aattcttgaa gaagaacgtt ctggtaaaac
     6421 aaacgatgct cttaaagaaa aagtagctgc aaacttcaat actgctaaag cagatgccgt
     6481 tcttggaaaa gcaggcgttg ctaaagaaga tgtagcagca aacaataata tcacaaaaga
     6541 aactaatgtc cttgttcttt gtgcaggtgg aggtacaagt ggcttgcttg ccaatgcctt
     6601 gaacaaagca gcagcagaat acaatgttcc agtcaaagcg gcagcgggta gttacggtgc
     6661 tcaccgtgaa atgttgccag agtttgactt ggttatcttg gctccacagg tcgcttcaaa
     6721 cttcgatgat atgaaggctg aaacggataa attgggcatt aaacttgcaa aaactgaagg
     6781 agctcaatat atcaaattga cacgtgatgg acaaggtgct cttgcatttg ttcaacaaca
     6841 gtttgattaa taaatttgta aaagttattt gagacgagat tattctttca gttccttata
     6901 atattgttaa ccatatcatt gcatttcatt tccttggttt ccggaactca gaatatcgtc
     6961 tcaaatgctt tttttgaaag gatttatagt tatgactaaa acacttccta aagattttat
     7021 ttttggtggt gctacagctg cttatcaagc agaaggtgcg actcacacgg atggtaaagg
     7081 cccagttgca tgggataagt atcttgaaga caattattgg tacacagcag agcctgcaag
     7141 tgatttttac cataaatatc ctgttgattt agaattagct gaaaaatatg gcgttaatgg
     7201 tattcgtatt tcaattgcct ggtctcgtat tttcccaact ggctatggcg aagtaaatga
     7261 aaaaggtgtt gaattctacc ataatctttt tgccgagtgc cacaaacgtc atgttgagcc
     7321 attcgtgact ttgcaccact ttgacacacc agaagttctt cactcagatg gagatttctt
     7381 aaaccgcgaa aatatagaac actttgtaga ttatgccgct ttctgttttg aagagttccc
     7441 agaagtaaac tactggacaa ctttcaatga aattggccca attggagatg gtcaatactt
     7501 ggttggtaaa ttccctccag gcattcaata tgatcttgcc aaagtcttcc aatcacacca
     7561 caatatgatg gtttctcatg cacgtgctgt gaaattgtat aaagataaag gttataaagg
     7621 cgaaattggt gtagtacatg cgttgccaac caaataccct tatgatccag aaaatccagc
     7681 agatgttcgt gccgctgagt tagaagatat catccataac aaatttatct tggatgcaac
     7741 ctaccttgga cactattcag ataaaacgat ggaaggggtc aaccacatcc tagctgaaaa
     7801 tggtggagaa cttgatcttc gtgatgaaga cttccaagca cttgaagcag ctaaagattt
     7861 gaacgatttc cttggtatca actactacat gagtgattgg atgcaagcct ttgatggtga
     7921 gactgaaatc attcacaatg gtaagggtga aaaaggaagt tctaagtacc agattaaagg
     7981 tgttggtcgc cgaatcgcac cagattatgt gcctagaacg gattgggact ggattattta
     8041 tcctgaaggc ttgtatgacc aaatcatgcg agtgaaaaat gattatccaa actacaagaa
     8101 gatttacatc actgaaaacg gtcttggata caaagatgag tttgtagata ataccgttta
     8161 tgatgatggt cgtattgatt acgtgaagaa acacttggaa gttttatcag acgcaattgc
     8221 ggatggtgca aatgttaaag gttacttcat ctggtcactt atggatgtct tctcatggtc
     8281 aaacggatac gaaaaacgtt atggactatt ctatgtagac tttgacacgc aagaacgcta
     8341 tcctaagaaa tcagctcatt ggtataagaa agtagcagaa actcaagtga tagagtaata
     8401 ttacttgaaa atgtaaaaaa ttgttatccg atactttaga aaaagtacaa cacttattta
     8461 gaccaggctt tgaaaaggta tatattgtta gtttcgaaga ttgtcctatg attcctgagc
     8521 ttgaagctac cccgttgcta aaatgtggta aatggtatgt ttcaactgga aaagagtgga
     8581 tttgccattc tgatttagag ttatcagcat ttgaatggga atttttacaa tcactcgatg
     8641 tagaaatacg tgagactatt cacttcgagg taaattattt gcctttccaa taataaaaag
     8701 aaaggaatta gttgtgacta tcgaattaaa aaacgagtat cttactgttc agtttaaaac
     8761 acttggtggt caactgactt cgattaaaga caaggatggg atagagtatc tctggcaagc
     8821 tgatccaaat tattggaatg gacaggcgcc tattctattt cctatctgtg gtagtttacg
     8881 aaatgattgg gctatttata gacctcaaga aagacctttt tttacaggtc ttattcgtag
     8941 acatggtttt gttcgaaaag aagaatttat tctggaagaa gtcaatgata atagcgtgac
     9001 ctttagtatt aaaccaaatg ctgagatgct tgataattac ctatatcagt ttgaactgag
     9061 agttgtttat accttgaatg gtaaatcaat tagaaccgaa tttcaggtaa cgaacttgga
     9121 aatggaaaaa acaatgcctt actttattgg agcccatcca gcattcaata gtcctttagt
     9181 agaaggtgaa aactatgagg attattatat tgaatttagt gaggttgagt cttgctcgat
     9241 accaaagagt tttcctgaga caggattatt agatttgcaa gatcggacac cttttttgga
     9301 aaatcaaaaa attctcgatt tggactactc acttttttcc catgatgcca ttacacttga
     9361 ccagctcaag tctcgtagcg taacgcttcg gtcaaggaag tctggtaaag gtcttcgagt
     9421 agattttgat gattttccga acttgattct gtggtctaca actaataaaa gtccattcat
     9481 tgctttggaa ccttggagtg gtctctccac ttcacttgaa gaaggtaatt tcttagaaga
     9541 taaaagacag gtaacgaaaa tttcacctca agaaacttct agaaaaatct atgatattac
     9601 tatccttaat taaaatttgt tattatttga gtcttcaata agatttgaat actcttacct
     9661 tgtgatgata gattggtctt ctccgtgcca gtcttacatc gcaaggtttt taagtttttt
     9721 gtgggtctat gtcaactgta gtgggtgacg aaaagctaat atctaaagac agtctggtag
     9781 taaaaaataa gattatttac tacttcttga tttaaaataa tagtggagcc attaatttgt
     9841 ggcaaattta atttaatatt ttgcctcaaa ttagccacac tttttataga actaagagga
     9901 aaaatgaaat tttcttccta ttaatatagt tgtttgaaat cttaaatata gcgttttgga
     9961 atggcaacag tttttttgac aaattttata aggtgcagaa cttctttccg tatgctattc
    10021 cgattgtcct tgacaatgag cctcctcgga tgtgacgatc ttcggcagga gctaacagtt
    10081 aaagttagac tgcctcgcta gcgttagcac atccgagctc attatcaagg attcgctgcg
    10141 ccaatctctg gttacggtaa ccaaccggtg tctcgtagcc aagtgtaccg tgcaaccgaa
    10201 ggtggttcca ccaattgaca tagtcaaata actccaaatc caattgttgt aaggtttcaa
    10261 atgtgtattg atagacaaat tctactttca gcgacttata agttgattca gctacggcat
    10321 tatcaaaagg acagccttta tg
//
LOCUS       DAPBBR010000084         9981 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPBBR010000084 DAPBBR010000000
VERSION     DAPBBR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.088"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(77..149)
                     /locus_tag="RD488_002490"
     tRNA            complement(77..149)
                     /locus_tag="RD488_002490"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="RD488_002491"
     CDS             530..1099
                     /locus_tag="RD488_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDT7658512.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="RD488_002492"
     CDS             1086..1946
                     /locus_tag="RD488_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7658513.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="RD488_002493"
     CDS             2136..2840
                     /locus_tag="RD488_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7658514.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="RD488_002494"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="RD488_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDT7658515.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="RD488_002495"
     CDS             4677..5993
                     /locus_tag="RD488_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658516.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="RD488_002496"
     CDS             5994..6863
                     /locus_tag="RD488_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDT7658517.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="RD488_002497"
     CDS             6918..7727
                     /locus_tag="RD488_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7658518.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="RD488_002498"
     CDS             complement(7830..8459)
                     /locus_tag="RD488_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDT7658519.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="RD488_002499"
     CDS             8629..9921
                     /locus_tag="RD488_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658520.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
BASE COUNT         3278 a         1729 c         2143 g         2831 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga g
//
LOCUS       DAPBBR010000085         9975 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPBBR010000085 DAPBBR010000000
VERSION     DAPBBR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.089"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..808)
                     /locus_tag="RD488_002500"
     CDS             complement(<1..808)
                     /locus_tag="RD488_002500"
                     /inference="COORDINATES: protein motif:HMM:NF013429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7658521.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTYSNCQAVKQLAQKHALDIIAFTPESIIYPYNIAAPETMQWEKSKAYFRNAILA
                     TAELGCSLMTINSGYGLMEEPIEESWKRSREMLRYLAEIAETEGVTIALETLRPEESK
                     IVTKLQEAQRMVHDVAHPSLKLMVDTAAMGVAGEGLQDWFKAFGDDIVHLHFVDGTPE
                     GHLAWGDGNFNLHEFLTILEKYDYQGFLGQEITDSRYLKRPYLADKQVFDK"
     gene            complement(841..2241)
                     /gene="yfcC"
                     /locus_tag="RD488_002501"
     CDS             complement(841..2241)
                     /gene="yfcC"
                     /locus_tag="RD488_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDT7658522.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFVGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            complement(2289..3788)
                     /locus_tag="RD488_002502"
     CDS             complement(2289..3788)
                     /locus_tag="RD488_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDT7658523.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKNVSTEDFFNYCRLEESG
                     VTVTSGTDLPLFITDIPESIIRAVFRRFPEGEEVWEKETSFTTTELLKSFTSNSFKVN
                     GLSEYGEIKVGKSASLAVFSEDLCTDDWQKVMAAEVIATYLDGDLVYKK"
     gene            complement(3824..4534)
                     /locus_tag="RD488_002503"
     CDS             complement(3824..4534)
                     /locus_tag="RD488_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7658524.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKQMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            complement(4602..5417)
                     /locus_tag="RD488_002504"
     CDS             complement(4602..5417)
                     /locus_tag="RD488_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HDT7658525.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKMGNEFAGKSCLVDGSFGFGIHYD"
     gene            complement(5428..6396)
                     /locus_tag="RD488_002505"
     CDS             complement(5428..6396)
                     /locus_tag="RD488_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7658526.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            complement(7130..8330)
                     /locus_tag="RD488_002506"
                     /pseudo
     CDS             complement(7130..8330)
                     /locus_tag="RD488_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            8351..9124
                     /locus_tag="RD488_002507"
                     /pseudo
     CDS             8351..9124
                     /locus_tag="RD488_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9303..>9975
                     /locus_tag="RD488_002508"
     CDS             9303..>9975
                     /locus_tag="RD488_002508"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658527.1"
                     /translation="MSMNHFIKQLFTIKDSNIQIQSFEETFYKSRKSIVIEGTLIRTY
                     RRCPCCKDSTKQIVKNGKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLV
                     TPFCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPR
                     CLLFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHY
                     IVTDMN"
BASE COUNT         3085 a         2070 c         1613 g         3207 t
ORIGIN      
        1 atttatcaaa tacttgtttg tctgcaagat aaggccgttt tagatagcgg ctatctgtga
       61 tttcttgtcc cagaaatccc tgataatcat atttttctaa aatagtaaga aactcatgta
      121 aattaaaatt tccgtctccc caggcaagat gtccttctgg tgttccatca acaaaatgaa
      181 ggtggacaat atcatccccg aaggctttaa accaatcttg aagaccttct ccagcgaccc
      241 ccattgctgc ggtatcaacc atcagcttca aagatgggtg tgccacatca tgaaccattc
      301 gctgagcctc ctgtaatttg gttacaattt tcgactcttc gggacgcaac gtttccaatg
      361 caatcgtgac tccctcagtt tctgctattt cagcgaggta tcgtagcatc tctcttgagc
      421 gcttccagct ttcttcgata ggctcttcca tcaaaccata tccggagttg attgtcatca
      481 gtgagcagcc taactcagcc gtagctaata ttgcatttcg aaaataggcc ttgctttttt
      541 cccactgcat cgtctctggc gcagcaatgt tataagggta gataattgat tctggagtaa
      601 aagcaatgat atcaagagca tgtttctgtg ctagttgctt aacggcttgg caattagaat
      661 aagtaaaagc atctatgaaa aaatgcggag cacctcccca aagttcaaca gaagaaatac
      721 caattttctg ttgataagcg aaaaattctt tgagagaata aaataaatag tggatattca
      781 ttcctgctaa ttgatttatt ttaatcataa ctattgcctc ctattaatgg atgattaaga
      841 ctaaaagagt gtagcaatgt ataacaaaac agcagaaaca agggttaaga tggcaaatat
      901 tttgaagcca accttaaacc atttagagaa attaatctct gcgatggcta atcctgccag
      961 taatacacca ctagttgggg agataatatt cattaaacca tttccaaact ggttacttag
     1021 aacaacaaca tcacgactta cattcattag atcacccaat ggtgccataa ccggcatcgt
     1081 taatgccgca gctcctgagg aggatggaac aaaaaaggaa acaattactt gagaaatgag
     1141 tagaatcgta gtgaacagga attttggaag accacctaaa aggttagcca agctgtttag
     1201 aatagtgtca ataatcattc caccttccaa gattaccaag actcctctag ctagcccaat
     1261 gattacagca gcataggcga aatctgaaca gccttcgaca aaagcttcag caatttcctt
     1321 ttgagaaaat ctagcgatgc ccccagcaaa aagacctaat cctacgaata gtgcagaaat
     1381 ttcaaccata taccatccct tggaaatgat accccaaatc atgattccta aacctacgat
     1441 aaaaccggcg ataattagtt tatcttgtgt tgaaaactct ttttcagtgt caaaattttg
     1501 aaacttatgc ttaaccttta aatcactctc ataaacaata gaggacagtg gattcttttt
     1561 gactctgcta gcataaagca tggtgaaaac aattgaaatc ccagtaatga caatccagga
     1621 tagcatccga aaccaaagca ggggatttcc gtaaacgcca gctactccct gtgcgattaa
     1681 aacgttgaag ggattaatcg tcgacccaac atatcccgct tgtgtactta aaaataaaat
     1741 caagatcgca gtcatggaat catagccaag agaaaacatc agagaaataa acaccgcaaa
     1801 taagggaatg acttcctcgc tcatgccaaa ggttgatcct cctaagctga atagaatcat
     1861 cgacatcgga ataactaaga tccccttgtc tcccagaact tttgctaagg taaacagccc
     1921 tcgatcgatg gctcccgttt ttaggataat cccgaaggca ccaccaacga tgagaacaaa
     1981 agcaacaacc tcaacagctg aaataatccc ttcagctggt gccattagta tagaggaaaa
     2041 accttgtcca taatctgcct tatcgatttg gtgataggtt cccggaacaa ccgttgtttt
     2101 ttccatacct gcgacgtttt caacaactgt ctcaaactga ccactaggaa ttatccaagt
     2161 taaaattgca gccaaaataa ttaagataaa aatcaatgta taactatgtg ggaaggtgaa
     2221 ttttcttttc attgtttcca ttttttaacc tctctttaat tcgtcttata acgttatatc
     2281 gaaaagcatt atttcttgta aactaagtca ccatcaagat aggtagcgat aacttccgca
     2341 gccatcactt tttgccagtc atcagtacag aggtcctcgc tgaaaacagc taagctggcg
     2401 cttttcccta cttttatttc tccgtactcc gataaaccat ttactttgaa gctgttgctt
     2461 gtaaaacttt tcagcagctc ggttgtcgtg aagcttgttt ctttctccca gacttcttct
     2521 ccttcaggaa aacgacggaa tactgctctt ataatcgatt caggaatatc agtaataaac
     2581 agcggtaaat ctgtaccgct agtgactgtt acaccacttt cctctaatcg acaataatta
     2641 aagaagtcct ctgtggaaac attttttata acagttgaca tgtaagcctc ttctaacgtt
     2701 tgattcaagc cgagaatttg tggatatacc tctgctacta cttgtccttc gttcattttt
     2761 tctgctgtct tttgagtaac catttccaaa tcactaatcg aattaaaaac gccttcaggt
     2821 aaccgctttc caaattcgac aagaattgac gcagctttat aacccgcttt atctccttcc
     2881 gttgtcaaac agcaaggaat ctctacttca ttgaatgcag caacttctgc tttaattgcc
     2941 tcatagtcaa tctcgggtga agctactcct gactgataaa caccgtaaat atctccactt
     3001 ctatccgcaa caacaccatc taccatgatc ttcactccac caaagcggac cttttcaggg
     3061 aaaacttttt ccttatactc atatagaagt tcatgctgta gaggttcttg gactgcctgc
     3121 acatataggt tactaagtat tttcctctga ggtatattag aaagaaattc tgcgtcatca
     3181 aaaacgattt ctttcattga tataacacct tttgaaagca gtaatgcttc aaattcagcg
     3241 taaacctctg ctaaaagctt tttgtttgct agcatttcct taattaataa tactcgactt
     3301 tcagcactgg tttctttttc tgtaaaacca taagtctgct tagcaatagc attcatccaa
     3361 caatggctgc gatttttgtc gatcgctgtg attggaccaa agtggtttat ttcattcaat
     3421 agctcttctg atgggtcagt tttccacagg gcagcatccc agccatgagc ataaattggt
     3481 tcatctgctt ttttatggtt cattacagct ttaatacgct ctacagcctc gttagctgaa
     3541 gatgtatcgc ttaaatctat gccagcattc atagccaaat aaccactgaa aaatacatga
     3601 ttatcatgaa ttgctggcat aacgaattga tcatcataag caattaattc cgtgttttca
     3661 tttaatagat cactgtaatt ccagttgttt tccacctttt caatgatccc ttcattgatt
     3721 acaatataac ctttgaaagg tggctgttct ccatcaaaaa tcatttttga ccgcaatatt
     3781 tgcttcataa ataaaatcta ctccttgaaa tcaaaacagg aaatcataag taaaaacgat
     3841 atacttctcc caggtaatat tgattaccta catgaattgg tatgttgttt tgatcgttga
     3901 ttaaagtatc cataaagaaa aagggcgtcc caacagctac ttccattatt ttggcaattt
     3961 ggtcatcagc tgtgacaatt tcaagtgcag tttccccagg attgatggct aaggtacctt
     4021 ggactttaag tacttcatac aaagaatcag tcagctcttc ctccattaag aaactatatc
     4081 tttcataaga aaaataattg ttttctaaca taatggggat gttatccgcc atttgctttc
     4141 tctggatata taaaacatca tcaccttgag cgatatcgag tttttttgcc atcccttcag
     4201 ttgctggaat gatcttgcgt tccaaaacaa tgctagtcgg tgtaaaacca ttagatttac
     4261 aactctcact gaaacccata acatattcaa ttttacgaaa aactttatgc cggttgacaa
     4321 aagttccttt cccttgtttt ttaagtaggt acccttcttc taccagttct tctactgctt
     4381 ttctcactgt gattcggctg acctcataac tttctatcag ctctgattca gcgggaattt
     4441 tcgtattctc gggatactcc cctgtattga ttttattttt taatatttct tttaattgta
     4501 agtacaatgg taattgtgca tttgtatcca gcattttttt aacctccact ttaccgggat
     4561 ttctttcttt aggttatcaa atgcaggaat ttaaaacaag ctcaatcgta atgaatacca
     4621 aagccgaacg aaccgtcaac cagacaagac ttcccagcaa attcattccc cattttcatc
     4681 gcggtgacta tatcgtcccc ttcgagaaaa taaagtagga aagctgttaa gaaagaatct
     4741 cccgctgcca ttgtatcaac tggttcttct agcacggggt tcacttcata aaactttgct
     4801 ccatcataac caatagccgt tttttctcct cgggttgcaa tcaatacatc atttcgctca
     4861 caaaaatgct tcatcaaaaa ctgctttact tcttcatcgg aaaagtcttc tatagaaaag
     4921 aagccaaaat caactttatc aatcgcccgc tgaacctctt cttccgtaaa gtcgtcagaa
     4981 aaatcataag aaatctttcc agaaacattt tgtaactctt ctaatagatg attgacatgg
     5041 ctatataatc ccatatgaat caattcaaac tggtttaaat attctctgtc ttcttcagta
     5101 agctgaatcg ggtattcacg agtaacacct cccgaattgc tgccaaggaa aatccggtcg
     5161 ccctcatcaa tcttcactct ggcacagcca ttctcgcctt tttcaaagcg agagtgactg
     5221 ttgtccagtc ctatttcttt tattgctgat aaaacatgag ctgcctcctc atctgagcca
     5281 aaaactccca taaagctact ttcatgcccc agtttttttg caaaaactgc aaaattcaat
     5341 gaatttcctc caggatacat aattcccaga ttttcatatt tatcgacgac gttatcacct
     5401 aagcctaata ccttcatttt aatcctccta gtactccact ttccccatat agcgacgaac
     5461 atctaaatca tgattgcgta catctgctaa agctgaacga tattctgaaa gaatactgta
     5521 gaataaaatg ggattgaaga attcagaaac ttcatctgat atcatatcca atcctagttc
     5581 ctttgcatca acgatttcta ctctttctgc atatttatca aggaatcgtt ttgcccgttc
     5641 atctaaagca cgagtgcgtc caatgctcat caagagaata aaattcgtat ctttgtctgt
     5701 tacttcaaaa ggtccatgga agaattctcc agaatgaaca gaagttgaat caagccattg
     5761 catttccatc aaagagcaaa ttgaaaaacc ataagcatgt ccatatgatg gtccactacc
     5821 taagatataa aacattgttt catctttgta cttatcagca aacactttaa tacgatcctg
     5881 cacctgctta atgccatttt caattacggt atcgataacc ttcatgcctt ctctgaattt
     5941 accgtaatgt tcaaatgttt cggtaacatt gaccaaagat acagttaaat caagaatgat
     6001 ggccatagga ttattgacta tttttgcatc atctccccat tcgtaaagga aactatgatc
     6061 agaaaccttt aataaatccg cagttttatt atgagtcaga ccaacagtca cagctcctct
     6121 agcttgagcg acttctcctg cttttaccgt ttctgctgta tttcctccat gagaacatag
     6181 aatgacaaca gatttatcat ctaattgctt tggggttaca tggttaaatt cgttcgctgt
     6241 atataagcct gtaatacact tcgatgcttc ggctttaaga aaataatctg agacatacat
     6301 atctaccagc gaaccgccac aagccaccaa ataaattcca gaaatctctc catcattttt
     6361 ttctacaatt gcgttaaccg tttttgctac atccatcaac atttcctcct taaaatttta
     6421 aaaatgttaa ttttatccaa aataaaagta actgattaaa tgtaaagata ttacataacg
     6481 tcatataacg tcatgtgaca taattgcatt gtatccgctt tctttgtgtt tgtcaatagg
     6541 aaaaatttat ttctctaaaa aatataaata atctgcagtg aaacttgagt acatatacta
     6601 atttcgaaaa atgcctatga tttaaataat tatggtgctg ggatgaaggt ttataagttt
     6661 gtcttgattt gtttagaaga aatcgttttt gcacacagtt gaattaggaa actactggag
     6721 tggaaaataa agtgatttga cgggtagatg ggtgcactta aatttgaaaa tggcttaaaa
     6781 tgctttattt tgaattgcag aatttctttt agtacgcaat ttatggtctt aaaactgatt
     6841 aaaaagtgat acattgattt taatacaatt tatgatacaa aaaatgacct cctttcttaa
     6901 ataaaagagg tcattttgtt ttgtctcata atcgattgtt tttgatacag tagttatatt
     6961 cagaaaaaat aaagactctt ctgagttgat aatcctttgg attatatacg gatacagatg
     7021 tagacataaa acaagctcaa ttttcaaaaa tggcattact cacctttttg gtgaattatt
     7081 aaactaaaaa agatgaattt ttttatgtac tataagatgt aggtgtactc tagttaaagt
     7141 aattctttat gtactctgta acatcgaata catcttctaa taaaaatgca cgcaataatc
     7201 tgtcaattag catatttacc ttgattggta ttaccatttt acctaaattt ttctcgatat
     7261 atccactgaa atgacctacg ttaacacttg attttaattt atcaaatcga ctatattcat
     7321 taatgtttac ctcggttaag cgtaaatcca acatctcacg taataatgcc tcattaatat
     7381 tggttgaatc cactaaatct tggataaaat cgtcctcttc actaagctga tattcattga
     7441 ggtaatcagt aaattcccat ccttctttga taactaattc cccattattt acatcattta
     7501 gaatcatctc agcatatggc tgtaactcca ctggtaattg cgcaaatgtg cgatgtaagt
     7561 cgtttaacaa tgattgaatt aaattcgaat cacgttcttc ttttatattc atgtattttt
     7621 tgaagtttgt gtttaaatac tcataattaa tacgactacg actaccttca ggtaattggt
     7681 aatcaatgtc atacgctata ctatcatttc cgtctctagg ttctctctat ctcgctgtaa
     7741 cgttgtgcca agatattaaa ttcatattct gtgattacta ctgttatagg ttcataatcc
     7801 tggatttcat aagtcgattt tgcccatgtg aatccctgta tcatcgctga ttcataacaa
     7861 tggattagtt gattataaag atttacaaat tgcttaattt cccctggaac ctccggtaaa
     7921 tgactgaagt tttctatgcc agaaatatta aatacggact taatttcttc gaatatatcg
     7981 ttcaactttt ctaagttatt atataatttt tcaacaaata acccttttgc ttgtttgcct
     8041 gagtataact caatagcctc ttcaatgttc tgttccatcg tatgtgcttt acgataataa
     8101 cgaatggttc cgaacggttt ttcaggacca ttaagacgat ttgtgcgtga aaaagcctga
     8161 attatgttct gatattcaag tgacttatct aagtataggg tgttgaccca ttttgaatcg
     8221 taacccgtta agagctgatt aacaactata acaagatcta attgggttgc ttcatctact
     8281 gttttgtaag gattcttatg cgctgtgttt tgcaatagtt ttgtacacaa gattgcaaag
     8341 aaaagtacac aatgttgcca cttctggttc catgagtttt atttgtgttg atgggacaac
     8401 caatcagcta tttacgaccc ttgaagatcg cagactttac aaactaactc aatacttcct
     8461 gcgctttcct agaaaggccc gtttaaaggt caagtaccta gtgatggaca tgaatgccag
     8521 ctattgtcag ttgcttaaaa cggtctttcc aaatgcggag atcgtaactg accgctttca
     8581 tattgtccaa cacatcaatc gcagcttcaa tcaattacgt gtccagatca tgaatcgttt
     8641 tcgaacctca cactctgaaa atcagaagaa gtaccgtcgg ctcaagcgat attggaaact
     8701 cttactcaaa gattccacga catgggaggc actcaaacgg cattatcatc gactgtttaa
     8761 acgaccaatt agtcaaacag aaatcgttaa tgagctgtta agctacaacg aagaattgcg
     8821 aactgcgtat catttttgtc aattattacg ctattatttc gttaaacgag atacggtagg
     8881 ctttcaagaa acccttaaaa caatttcatc tacgttacct cagtcgttta aaaagaaatt
     8941 cacgatcttc catcgctacc aatcgggtat ttcaaatgcc tttaaggtgt cccactcaaa
     9001 cggcgtcact gaggggctgt ataacaagat caagctgatt aaacgaattg cgtttggtta
     9061 tcgcaacttt tataactttc gggcacggat ctatttacaa caaggtctga tctttgaaaa
     9121 ctaaaaaaat atgcggcgca cagaacgcgc cgcatatcgg actaagtttt attggctcta
     9181 taatttctag gactgatgga aattttctat ctgtcctagt ttttttgtaa aaaaacaaaa
     9241 agacatacaa aatttccggt agaatagagt ctcctacaac atcattctgg gggaattctt
     9301 gtatgtccat gaatcatttt atcaaacaac tctttactat taaagactca aatatccaaa
     9361 ttcaatcctt tgaagaaact ttttataaaa gtagaaaaag tatcgttatt gagggaactc
     9421 tgatccgtac ctacagacgt tgtccgtgtt gtaaagattc tacaaagcaa atcgttaaaa
     9481 atggcaagaa gatctctatg attctcctga atcgtagcgg taataaacgg acctatcttc
     9541 ggttgaagaa acagcgatac ctctgccgag catgtaaaaa atattttacc gctcggacgt
     9601 atctcgttac cccattctgc tttatttcta agcagattca ttacaagatc ttagaagaat
     9661 tgacagagcg tcaatctata aaagcaattg gtaaacattg cgatgtttct gtgacaactg
     9721 ttcagcggac attgtccgcc ttgtcatcag atatccgtca gaatcttgag tatttacctc
     9781 ggtgtctatt attcgatgag tttcgttctc tttctacatg gcacggtaaa ttttcttttt
     9841 cttgtatgga cggtgagacc gggaaactgt ttgagatctt acctagccgc cgtaaaaaag
     9901 atctcgttgc ttttttcatg cgtttttctc tcaaagcgag gttgggtgta cattacatcg
     9961 taacggatat gaacg
//
LOCUS       DAPBBR010000086         9927 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPBBR010000086 DAPBBR010000000
VERSION     DAPBBR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.090"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            3..359
                     /locus_tag="RD488_002509"
     CDS             3..359
                     /locus_tag="RD488_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HDT7658528.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            375..725
                     /locus_tag="RD488_002510"
     CDS             375..725
                     /locus_tag="RD488_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HDT7658529.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            754..1533
                     /locus_tag="RD488_002511"
     CDS             754..1533
                     /locus_tag="RD488_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HDT7658530.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1544..2221
                     /locus_tag="RD488_002512"
     CDS             1544..2221
                     /locus_tag="RD488_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HDT7658531.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAMILG
                     AIFPAVN"
     gene            2240..3346
                     /locus_tag="RD488_002513"
     CDS             2240..3346
                     /locus_tag="RD488_002513"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDT7658532.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3336..4427
                     /locus_tag="RD488_002514"
     CDS             3336..4427
                     /locus_tag="RD488_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDT7658533.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4440..5180
                     /locus_tag="RD488_002515"
     CDS             4440..5180
                     /locus_tag="RD488_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDT7658534.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            5468..7408
                     /locus_tag="RD488_002516"
     CDS             5468..7408
                     /locus_tag="RD488_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDT7658535.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            7495..9417
                     /locus_tag="RD488_002517"
     CDS             7495..9417
                     /locus_tag="RD488_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDT7658536.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(9697..>9927)
                     /locus_tag="RD488_002518"
     CDS             complement(9697..>9927)
                     /locus_tag="RD488_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HDT7658537.1"
                     /translation="LIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDLKDPAQA
                     VGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
BASE COUNT         3237 a         1648 c         2205 g         2837 t
ORIGIN      
        1 tcatgattaa agtagttatt gcagaccgta tgggtaaagg acaaaatgtg gccaaagggg
       61 tagaagcagc tggtggaaaa gcagttgtcg taccaggaat gggggcagat atgcgtttgg
      121 gcgatgtgat gcaacaagag catgcagata tgggtatctc tttttgtggt agtggtggtg
      181 caggtgcatt aacagcagca acaaaatatg gctatccaga acgacatggt atgcgttcga
      241 ttgaagaagg gatcacagct atcaaggatg gcaaaactgt tctaggtttc ggctttatgg
      301 atcaagagga attagggaaa cgtctgacag aagaatttat caaaaagcat ggaaaataga
      361 aagagggaca tgaaatgagc gttcaaaaga caattcagca aaaagttatc gtctccggta
      421 aaggggaaac aaagcaacat gcttttgcat cagcgttagc agaaattcaa aacaaaataa
      481 tggaacaatc aaacgtatta ttgcgaatcg aaccagtcaa tgtggatatt ttaaaggcgg
      541 tcgaaaacaa atacacagaa cgctttctat ttttcttctt cccacggcaa cgtattagct
      601 atgaagtcga actctctgtt actgtggctg taacagaaat aaaattggca gacatatcgt
      661 tcagccagca aatgactgaa gatccaaatg ggattgccat tccatttgta actaaaaaaa
      721 tctaattttg aatcataagg gggaaagaat aacgtggatt tcgtaatcat tctagtcaaa
      781 tcggtcatta tcgggggatt acttggtttt gcagcatctg tcggggcagc tcgaatgttt
      841 catgcaccta atacacaagg tttaggagct tttagaacat taggcgaaat gaatgcctgc
      901 atgggtgatc cagcttctca tttttcattt ggtttaggct ttttctttaa tgcatgggct
      961 tcttcagttg gtgctggtgc attcacacaa gatgtgacgc atcgaatcat tcccaattgg
     1021 gcagcggcag cacttctagc aaaaaacaaa gatgtcaccc agaccatgca tgatccgaaa
     1081 aaaatgggga tcattggagc ggttatcggg gcagtggtgg tagccttctt aaacacaaca
     1141 gctgcagcaa ttccagaggc gttacaagtg acggcggttt ccgttttggt accagcagcg
     1201 acgattctga tcaatacagt aatgccagtt attttttggt tggcagcttt agacgcaggg
     1261 aaacgaactg gtttttgggg cactcttttt ggtggtatcg cgcaattgat tatgggaaat
     1321 gcggtacctg gtgttgttct aggaatcttg attggtaaag gcgtcgatga gagcggttgg
     1381 aatcgcgtca cgaagagcat gatgatcgct attgttttat tatttatttt cagtggattt
     1441 ttccgtggat ttgatatgga aatgatcaag agcttccagc ttcaagtgcc taattggctt
     1501 gataacttgc acaacatctt tagtgtgaaa taggaggaga atcatggaga caacagaaga
     1561 acaagcaaaa gtattagaag caaagcggca aaagagcttt tggtttgcag actggtcttt
     1621 tccgctaatc gtaggaatta tgtccgctgc tgtatttgca ggaacacaca tgtatgtgat
     1681 gtatggtgtg ggtgcattca atgaagtttc gatcgtggcg atgttaaaag ccgggctgga
     1741 tggcggatcc tatggcgcag cggcagcgtt tggtgctagt ttcttatttg ccagaatttt
     1801 agaaggctct ttagttggga tcttggactt aggcggttcg atcctaactg ggatcggaat
     1861 tggggtacca gcaattctct taagtatgaa aatagcggca ccaatcgata attttgcact
     1921 ctctttattg actggtttgg ttctaggttt gattgttggt ggcatcattg tcttgattcg
     1981 taaatttacg atcaatcaat caaattccac ttttggtgct gacgtcatga tgggggcagg
     2041 aaattcatct ggacgttttt tgggtccatt aattatatta agcgcgtgtg cagcatctat
     2101 tccaatcggc attggcgcta cattaggagc actaggattc tatgcttgga aaaaaccaat
     2161 tgctggaggt gctattttag gagcaatgat tttaggagca atcttcccgg cagtaaatta
     2221 atagaaagag ggtcattaaa tgtttgatac tttgattaaa aatggaaggt tagttgatgg
     2281 atctaaaata gaggtcgcta tagaaaaagg catgattaaa gcagttgcag cagaaataaa
     2341 tcagccggcg caagaagtag ttgacttgga gggaaagtat tatttatccg ctgggtggat
     2401 cgatgatcat gtccactgct atgaaaagat gaatctttat tatgactatc ctgatcagat
     2461 aggggtcgaa aaaggtgtga cgacggtcat tgatgctgga actacgggag cagaaaacat
     2521 ccgtgaattt tatcaattga cgaaatcggt caagacaaat gtgtatgcgc taatgaatat
     2581 ctctaaatgg ggcattgtca aacaagatga acttgctgat ctaacaaaga ttcaagaaga
     2641 tctagtaagt actgcgttag cagaactgcc ggaatttatt gtcgggatta aagcgagaat
     2701 gagtaagaca gttgttggtg aaaatggcat taagccatta gaattagcta aaaaaatcca
     2761 gacagaaaac aatgatctgc cattgatggt tcatatcggt tctgcacctc ctgagttaga
     2821 agaagtattg tcaagaatgg aaagaggcga tgtattgacc cattgtttta atggaaaacc
     2881 aaacggtatt ttagatccaa agacagatca aattaaaaac tttgtctggg atgcttacaa
     2941 taatggtgtc gtctttgata ttggacatgg gacggatagc tttaatttcc atgtggcaga
     3001 aaccgcacta aaagcaggaa tgaaagctac ctctattagt acggatatct acatccgcaa
     3061 tcgtacaaat ggcccagttt ttgatctagc aactacttta gaaaaattga gggtagtcgg
     3121 ctattcttgg gaagaaatca ttgaaaaagt tacagcagtt cctgcacgga attttcattt
     3181 gaagaataag ggccagttag ctgtcaatta tgatgcagat ttgacgatat ttgagattgt
     3241 tgaaaatgaa aaggaattga aagattccaa cggatttaca cgtatagcta aagaacaaat
     3301 tttaccgatt aaaacaatta ttggaggcgt catatatgac aattagctat ggaaagtttg
     3361 atttaaaaga agtcattaat gcatcgggaa aaatgacgat cctaggggtt tctaaggtat
     3421 ctgaaagtgt cctagcagca caacgatttg gaggcgagca tttttttgag atgagtgatc
     3481 ttgccatcaa aaccggcgct tatctttctc aattactgaa agtggaagat gcgcaaatcg
     3541 tttcttctgc ttcagcaggg attgctcaat ctgttgctgc tttaatcgga cagggcgaca
     3601 tgtaccatgt ctatcatccc tatacagaaa aaatcgctag acgggaaatc atcataccta
     3661 agggacataa tgtagattat gggacaccgg ttgaagtaat ggttgctcaa ggtggaggaa
     3721 aagtcataga agctggctat gcaaatatgt gtacaccgga acatgtttcc atgatgatta
     3781 cggaaaaaac tgctgcgctt ctatatatta aaagtcatca tgcagttcag aaaagtatgc
     3841 tgacggtggc agaaatggta gaagttgcca aagctcatcg tttgccattg atcgttgatg
     3901 cagctgcgga agaagattta ttcaaatata gcgaaatggg cgttgactta gtgatttact
     3961 ctggggcaaa agcaatcgaa ggtccgagtg ccggactggt cataggaaaa aagaagtata
     4021 ttcaatggat tcggctacag tctaaaggta ttggccgagc aatgaaaatc ggtaaagata
     4081 atattttagg ctttacccag gcactagaag attatttaaa aaatgggagc gaatccggtg
     4141 actccatgaa gcaacgatta gcgccttttg ttaacgcaat caatcaactt cctgaccttt
     4201 cagcgaaaat agttcaagat ggtgccggca gagatattta tcgagcaagt gtaacgatta
     4261 atggcgataa aagtgcgaaa gaagtcattc aggaattaaa agcacgaaat ccagcagtct
     4321 acacccgaga atatcaagca aataacggaa tcattgagtt cgacattcgt tccgtcagcc
     4381 aaaacgaaat ggaaaaaatt ataaaaagat tgagagaaat catgtaggag gcttttaaat
     4441 tgtcagttat cccaaattat tataaaaatc gtgtatgttt aaatgtatta gctcattcag
     4501 ttgaaaatgc aaaagcatgc tatgaagcag cggaagggca tgtcgtacta ggtgtgctat
     4561 cgaaaaatta tgctagcgat gaagcagcaa tcgaagatat gaaaaggtac caagacgcaa
     4621 ccaataatgc gttgtcagtt ggattaggcg ctggagatcc aaaccaaagt cagatggttt
     4681 cgcgtttatc tggggtttta caaccacaac atgtcaatca agtatttact ggcgtgggga
     4741 cttctcgtgc tttattgggc caaaatgata cagtcatcaa tggattggtt tcaccaacag
     4801 gtaagatcgg ctatgtcaat attgctacag gtccgttaag ttcacaagcg ccagcagctg
     4861 aagtgcctat tgaaactgcc attcaaatgc tgcaagacat gggaggtact tcaatcaagt
     4921 atttcccgat gaaaggctta gcacataggg aagaatttaa agcagttgcg gaagcttgcg
     4981 caaaatatga attctattta gagccaacag gaggaattga tctttcaaac tttgaagaaa
     5041 ttctgaaaat tgcaatcgat gcaggtgtaa aaaaagtgat tcctcatgtt tatagttcaa
     5101 ttatagataa agaaacagga gatacgcgta taggagacgt aaagatacta ttaagcatgg
     5161 taaaaaaaat tattcactaa ctcattagaa aataagaagc ttattccaga atgaaattaa
     5221 atggaataag ctttttataa ttaattacgg aaattgttaa tgtagataat aatttagatg
     5281 tacgtaagca gaagtacaga aatgtaagat tttccaatat tattttattc aacataataa
     5341 atcgtatatc aattttttta gcgaaatttc tatttattcc aagaatttca gttattacgg
     5401 aatcattttg tgcttaataa aaagaaaccg tttttatata ctataaatgt agaaaggcgg
     5461 taggaaaatg aaaaaaatta ttgcaatcac atcctgtcca gttggtattg cccatacata
     5521 catggcagca gaaaacttag agaaagcggg gaaagcagtt ggcgccgagg taaaagtcga
     5581 aacacatggt tccatcggta ttgaaaatga attgactgca agagatatcg aagaagcagc
     5641 tggtgtaatc atcgcagcag atactaaaat agataaatca cgattcggcg gtaaaccttt
     5701 gataaccgta ggtgtgcaag aaggaatcca ccatgcagat gagttggtga gagatatttt
     5761 agcaggaaaa gcgccagtct ataaaagtac ggaggcaatt atttcttccg aaaataaaag
     5821 tgaatcagaa aatttaggta aaaaaatcta taagagtttg atgaatggcg tttcgtacat
     5881 ggtacctttc gtagttacag gagggttatt gatcgcgatt tctttaacat taggaggaac
     5941 agctacacct gaagggatca agataccaga aggaacgatt tgggcaacga tgaatagtat
     6001 cggaagtatc gctatggggt tgatggttcc aattctatct gcatttattg cgcaaagtat
     6061 tgcagatcgt ccaggacttg ttcctggatt tgttggtggg atgttagcgg caaacggagc
     6121 attatatggt agtgatgcga atgcgggatt cttaggcggg atcatcactg gatttttagc
     6181 aggattcatt gctttaggaa tcaagaaagt gcgagtaccg aaagctttac aatcgatcat
     6241 gccaattatt gttatcccaa ttttaggatc attggcagtt ggttttgtgt ttatctatgt
     6301 tattggagaa ccagtagctc ttctatttag ttcattgact cactttttag cagggatgca
     6361 aggaggaagt gaaattgttc tagctatgat cttaggagcg atgattgctt ttgatatggg
     6421 ggggccgttc aataaagtag cctttttgtt cggatctggc ttgattgcag aaggcaatta
     6481 ttccattatg gggccaattg ctgtagctat ctgtatccct ccattagcat tggggctggc
     6541 atcattgatt ttaaaaacca aatttacgaa aacagaacga gaagctggta aggcgtcctt
     6601 agcaatggga ctgtttggga ttacagaagg cgctattccg tttgcttcaa cagatccact
     6661 acgggtgatt ccaagcattg taatcggggc aatgacagga agtgtgatcg cgatgctttc
     6721 aggagtgaca gatcatgtag ctcatggcgg tccgatcgta gcggttttag gagcagtgga
     6781 tcacgtagcc atgttttttg tagcagtgat tgctggtatt gctgtaaccg tgctaatgtt
     6841 aagaatcctt aaaccgacat tacaacaaac tgcggttgct gcagcaaatg gtgtgacagt
     6901 agcagatcta tcagagactg aaacaagtga tgtttatacg aaaactgaaa cttttgattc
     6961 tatcacggat attatgtcag atgaagcaat cgttttaggt gaaacagcaa caacaaaaga
     7021 cggagtaatc gaagatttag tccaacgttt agaaaaaaca gcggcgatca cagataaaac
     7081 cagatttaaa gaagtcatct atgatagaga acatgaaagt acaacgggaa tcggtatggg
     7141 gattgctatt ccacatggaa aatcagctta tgttcttaaa ccaacagtgg catttgccag
     7201 aagtcaatct ggggtagatt ggcattcttt agatggaaaa cctgcacata tgatctttat
     7261 gattgctgta cctgaaaaca gccaaggtga tatgcacttg aaaatactgc aacgtctatc
     7321 acgtaaattg atggatgatg acttccgtca agcactgatg gaagcgccag ataaaacaac
     7381 agttcaccaa ttattaagcg aaatgtaaca taagatgaaa aatcgaccgt gatgagacat
     7441 aatagatgtg ttatcatgat cgatttttta tttagaaggg agtttctgca cattatgaat
     7501 cagcgtcagc aatctttgat ctatcaatta agtgagaaca ataattatat aacaacaaaa
     7561 aagctagcag agcatttcca tgtgtcagaa agaacgattc atagcgattt gaataccatt
     7621 gaaacttggt tgagagacaa acatctgcct ttaatgtttg aaagaaaaaa aggtacaggt
     7681 atcttgttga atggtctgcc tcacgaaagg gaacaactga aacgagcgct taatgaagag
     7741 actcaaacag aaatggataa aaaacagctt cgtcagttat tgattttcca tctgctagta
     7801 gcaaaagacg gatttagtct tgaagaactt tcagaaaaac tatatgttgg aaaacgtacg
     7861 attcgtaaag aattgacaga gttgcaaagc ttttttgagt atcaccattt acagctagta
     7921 tccaaaacaa aactaggaac ttttcttaaa ggcgatgaac aagaaaaaag acagttgctt
     7981 gttaagacat tacgaaatat gcagaaagaa gatccacaaa gtccgtcgtt gaaagaattc
     8041 ttcgctaaag atacattaaa agttatccaa catacattac aagatgtttt ttatgaaaac
     8101 catttagaac agccgaatgg actggctagt gtggagattc acatctactt tatgctcgag
     8161 cgaatgaaac agtaccagaa agtgaaatta agtaaagacg aaaacgaagt cgtggaacac
     8221 acccaagcac aaaagttaag tagtcaaata ttagcaaaac tagccaccat ctatccaatt
     8281 gaattttctc ctgatgaaat caattatctg gctttgcgta tcgccaatct ttttacaaat
     8341 tcacaagcag ccacacgttt tcaaaaggaa tctagcgcac ttgctgatca tttgatcgaa
     8401 caagtggaac agtttctagg ctattcatta aaagaagatc agctactaaa acaaaattta
     8461 aggtctcatt tatcttcaac ttattttcga ctccattatg gtttgcagat ttctaatcca
     8521 ttgacgaaaa atgtgtttag tacgtacaca caacttttct tagttttaca gttaatttta
     8581 gaagattatt ttgaaaagga aaatttttat gttccacaag aggagacagc ttatttaacg
     8641 atccatttcc aagcagcgat cgagcgacac aaacatcaga aaagtagaag atatcaaacg
     8701 gttttagtta gtgaatattc aaaagctatg gctacttttc tcgaagcacg gctgaacaga
     8761 gaacttccag aattaacgat tatggatcta gttgaatata agccagaatt aaagagacaa
     8821 gattttccct ctgttgattt tatcttggct acgttaccat ttaaacatat aagcattcca
     8881 gtaatcgaga tctcaccaat gatcacagaa actgatctag cctatttgac aaaatatatg
     8941 ctggagcatg tgcctatcaa gaagaaaaaa acatttgatc tagcaagctt tactcatcca
     9001 tttctgatct ttcctcaact tgaacggaca gacccagccg atattttaaa ctttatggga
     9061 aacgtcttag tggaacatca ttatgtggag ccggaattca tcgattctgt cttggaaaga
     9121 gacagtcact ccagtactag agtagcacca tttgtaacaa tccctcacgg taatccgctg
     9181 tatgtgaagc attcgatgat ttctattgct acaatgaaag aaccagtcct atggcacggg
     9241 gaacagatac gtatcgtact gctattagca ataaagaaaa atgatttgaa acatgcagag
     9301 ttcaaaaaaa tattttctgt tattcactat ctagaaaagc agccagaaca aatggctcag
     9361 ttgatgcaat ccaatcatcc gctagaaatc ttaacgttgt tatctagtta tgaataagta
     9421 gcgattaaaa aactgccttt atatttataa taattctatc tatttatttg gaagtagaaa
     9481 actaaataca aaaaaagagg atgtggccaa agttgtggca catcctttta ttttgagttt
     9541 cttataattt tttatagttg cttacgatgt cttgactact ggtaaacggt gttcaagaga
     9601 caatttgtcg gcaataaggc acaattttgt aaaatatgga aagctatttt tttaacattg
     9661 tttcttagtg cttgaaaaat cattttgaat acttctttat acgatcgatg tacgttgatt
     9721 taagtctaaa acttttcttt tgattccttc tctgactttt ctgaattccg ttaatatttc
     9781 ttcttcgctc ccgacagctt gtgcaggatc ttttaggtcc cagtgaaggt gttcgtgatt
     9841 gtttggaacg gcagggcact tgtctttggc atcaccacaa agtgtaatga tcaagtctgc
     9901 ctgagtaaag taatctctat caatcaa
//
LOCUS       DAPBBR010000087         9233 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPBBR010000087 DAPBBR010000000
VERSION     DAPBBR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.091"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            114..494
                     /locus_tag="RD488_002519"
     CDS             114..494
                     /locus_tag="RD488_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDT7658538.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            476..1390
                     /locus_tag="RD488_002520"
     CDS             476..1390
                     /locus_tag="RD488_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDT7658539.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            1635..2324
                     /locus_tag="RD488_002521"
     CDS             1635..2324
                     /locus_tag="RD488_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658540.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(2445..2531)
                     /locus_tag="RD488_002522"
     CDS             complement(2445..2531)
                     /locus_tag="RD488_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7658541.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            3168..4112
                     /locus_tag="RD488_002523"
     CDS             3168..4112
                     /locus_tag="RD488_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDT7658542.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            4133..4666
                     /locus_tag="RD488_002524"
     CDS             4133..4666
                     /locus_tag="RD488_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7658543.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            4681..4851
                     /locus_tag="RD488_002525"
     CDS             4681..4851
                     /locus_tag="RD488_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658544.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            5261..5695
                     /locus_tag="RD488_002526"
     CDS             5261..5695
                     /locus_tag="RD488_002526"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658545.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            6985..7908
                     /locus_tag="RD488_002527"
     CDS             6985..7908
                     /locus_tag="RD488_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7658546.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            7924..8463
                     /locus_tag="RD488_002528"
     CDS             7924..8463
                     /locus_tag="RD488_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7658547.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         3466 a         1541 c         1646 g         2580 t
ORIGIN      
        1 agagcttgcc aagcccttta gtgagcttta gtgagcttta cttattgtac ctttttaggt
       61 acaatggtat tgcgaacgat acgtccgtag gacgtactga aagggtggga cttatgagcg
      121 aacaaaatca atatttggct agcaatcatt ctaaaaaata tacctatcga tccgagccaa
      181 aacaaatcag ttttcgagtg agcgaatccg aatttgcaaa gctgaagcag tcagctgaag
      241 ctttgcaaat gagtgtgccg gctttcgtga aagccaaggc acaaaacgcg cgtctggtga
      301 caccgaaagt ggcgccagac attgctcagg caatcgcgcg cgatttagcc aaagctggcg
      361 ggaatatcaa tcaaattgcc aagtggtgca acacacacca acacgacgtt gatcctggcg
      421 acgcccaacg cttatccgaa aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc
      481 aacagttaaa gtaagccgaa ccacttcttg tagccgagcg atcaattacg ccgaaccacg
      541 agcaaccgtc aaaacaggga taaactgtga cattgattat gccaaaagcg aaatgaaaca
      601 aattcgcatg ctgtatggaa aagacgatcg tgtacaagca cacttattga tccagtcttt
      661 tcgaccagga gaaattaccg ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa
      721 aatagcccct gaccaccaaa tcgcgattta cacacataca gacaaagacc atattcataa
      781 ccacattgtc attaactccg tcaatctgga aactgggaac aaatttcaag cccatggtca
      841 agcattttta aacaaatgtt atgacctaaa tgacgagatt tgtcttgaac atgacttaac
      901 aatcactgaa cgagggaaga aacccgaaaa acgaaccatg tctgaaatca aattaaaaga
      961 aaaaaatgaa cctgtttgga aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa
     1021 caaaaaaact cgaacgtata accaattttg tgattctctt aaaacattcg gcattcattg
     1081 cttgaatcgt gggaaaaatt ttacttacga attgatccac aaaaagaaaa aagtacgatc
     1141 caacaaacta ggaaaggatt acgaaaagga gacgatttta catgagctgg acagacgaga
     1201 acgagcctac aatcaacaac gaaccaacga gctacgaaga gctcgagcta gcattcgcga
     1261 aactgcaaaa gaagtacgaa gagaacaacg aactcttacg actgaacaac cggaaattag
     1321 accgactcga agaaaccatg accaacacgt tgaaagagga gcagactacc aacaagaatt
     1381 atcgttctaa aacgttacaa gacatagaaa atgaaataaa gaaacaacgt gcttttcttg
     1441 caccttatac caaagaaaga atacaaacta caattgattc acaagtcaaa aaattccacc
     1501 atgcgctatt aaaccagcga aataaagaac agaaaaaagt aattatgcag cgatcaatgg
     1561 atattcttgc ccccttatgt tgcttaatca tgacactgtt agccttttgg ctggtatggg
     1621 gagaataaat agaaatggca ttctatttac cctatctact catttttgcc agtattttag
     1681 gaattatttg gcttagctat aaggcttatc aaacaagata ttcattaaaa ggctctaaaa
     1741 ttcgatttaa gaggttttta ttgccagggg ttatatttac attatcaatc gttttaagtg
     1801 gtttattcgg cgttttagag ggaaataaac gtatttcaag aagtatttta ttaggggata
     1861 tcactcaaaa gtatgaagca gcatgtgata aaaagaaaaa ggagcaagtg ttaacacaaa
     1921 aaatggaaga gtttaccact tgttatgagg aaatgaacga tatttttgtg aatcaagaaa
     1981 aacgtttgac ggataaaaac atggaaaaac tcactcgtct ttatcaaaac ttgccagaaa
     2041 aacagcaaaa agaggttcaa gacaactatg agcgaaccaa aaaagacgtg caatatttta
     2101 aagatacgca gacagaagaa gcttgttata atttattcag tgatacaatc cctttttcaa
     2161 ctagtgaaca ggaacgaaaa gaacggcaac aatcagttac ctacgaacgt tataaagcac
     2221 tgcttcagca agcaacgaac atacaaaatc caacgaaaaa agaaacggca ttaaattatc
     2281 taaaaagtgt caaggaatgg ttagatcagc aacagcaaaa ttgaatttga tcggcaatca
     2341 tgttaaacta aacatgcaaa tgatcaaaca ttagatacac gaaagcccca gagaggtcgg
     2401 attctctggg gctttttttc aggttgatgt cgcctttatt gattttactt cttgtttcgg
     2461 ttattcaacc aataactgaa taaagagaca caaacttcta taagaagggg gcaaatgaac
     2521 aattcaaaca ttagatacac ctccttccag tcgcaagact gtcggatagg cgacaagtta
     2581 ttatatctta aaaaattaaa cttgtgtggt gtttttaagt atcgcttatt ttagggttgt
     2641 tagggcttgc cctgaccgcc tgtaaggcgc tttaaagcta gataaggatt tttatccaag
     2701 actgtcttaa aacggcttag ataagcattc agaaccgctc aaaggcctct ttaccaacat
     2761 gtttttagca aaggagcctt taggcgactg cgcagtacaa tgtgagagcg tagcgatcac
     2821 acctttttgg cgaccgtagg aagcaaggtt ttggattggc agttttgaaa aatgcgcgaa
     2881 cctgtttaaa gaaaaaagaa gtggttttta ggcgggaaaa ttagcccccc tctttttata
     2941 tctcttttta aacctctttt taaacctctt taccgtaagc tgtgtcctta ctctaccaat
     3001 ggatacagaa tgttatgaag gacattttgt ctgtttatga aggacatttt gtctgtttat
     3061 gaaggacatt ttgtctgttt atgaaggaca ttttgtctgt ttgaacgtca aatatgaatg
     3121 tcttgacatt taaaaaatgt cattcataat tggattgagg tgattatatg gctaatgaga
     3181 ttgtaaaata ccaccatgaa ttaaatacaa ttcctttaag aaaatttaca ccggttgaaa
     3241 tgaatttgtt tttttccatc gtgtctagaa tgcgtgaaaa aggggataag acagttcgtt
     3301 ttacgtttga ccaactaaaa gatttaagta actacaaagc aactgcaaat gtacgatttg
     3361 tagaagattt aaaagcaact tatgaaaaaa tcttatcttt acgctttggt cgtagaagtg
     3421 agtctgggct ttcttacgat atgtttgtaa tgtttacaga atttaaaatc aacggggacg
     3481 tagaaaatcc ttacgtagat atacgaattt acgaaaaagc actgcctttg ttaaataatt
     3541 tagacgagtg ggtacgctat tctttacaac aattcaacga gctacaaagt ggctatgcaa
     3601 agactatgtt tcgtctgtta aagcaataca gaaccaaagg tttcgcatat ttctccaaag
     3661 aagactttct tgaattatta gatattccta aaagttataa gcaacctgat atagataaac
     3721 gagttataaa acctatacgt caagaactaa ctgcaatctt caaaggacta acaatcaaaa
     3781 agaaatacgg aaaaggacgg ggaaaacctg ttattggcta tcaatttacg ttcaaacctg
     3841 agatcaaaaa agcagacgac tttaacaaac atgcaccaac caaagaagac caaaataaag
     3901 cattggcttt agctgataaa caaaaagaat acgaagaacc cgctacaaca attaacgaaa
     3961 aaatcaaaca gaagaaacga gaacttgaac tcctccaaca aatcaaacaa ctagaaaaag
     4021 agaaaaaagc tcttgaaaaa caaacagagt ccgcactttc ggaaaaagag aaaaaaagtt
     4081 tattatctga tttagataat ttattccagt agcaacctag gaggcaacca gtatgcaacc
     4141 acaagaaacc tttacaataa aggaattgtc agatcttttt aagatgagta ggcaagcaat
     4201 atcgaaacat atccaaaaat tagattcttc catgatagct aaaaatgagc gtggttataa
     4261 ggttgtattg cgttctggag tattgcaact tgctcgcaac ttagacaatc aaaggttgct
     4321 agataagttg cataaacatg aacaaaacaa cgataaaaat gcttatatac caaacaaaaa
     4381 cgtggttgca aacaagttgc tagatcagtt gcgtgaagaa aatgaatttt tacgagaaca
     4441 acttgccctc aaagagcaaa ataattctca tatacaaaaa ctactcgacc agcaacaaca
     4501 actcaccctg caagccaacc aacaaatcga aaaacttcag gagcaactgc agttgactta
     4561 tacggaagag tcttcagaga atagttcaac gactctttct gaagcaacag aaacaatgga
     4621 cgaacaaaca aagaattgga aaaaatggtg gcagctatgg aaatgaagaa ggaaatactt
     4681 atgacaaaaa aacacttgct attcggttct atcctactag gaatattaag ctttagccca
     4741 atgttattat cagtggccaa caaaggaaat aaaaaagggg aactaaaact caatcctaat
     4801 tactacaaca gtcaaaatga ggaagtattt gtagaaaaac ttgataaata agaaaagact
     4861 gctcgtacga gcagtctttc tgaaagagat tatcctatta ttaaccttag aaaagaataa
     4921 taaatgaata tgagatatgt aaaaagcata acaaacacaa acaaaaataa caagtattta
     4981 aaaaatgacc gatcaatatt cacaaagaat tagaaagaaa caaccgcaga aaaccaagcc
     5041 ttaaaaagag cttttaacct agaccaataa aaattcacaa aatcagcgcc tggatccctt
     5101 ggtacaggcg ttacttggta gtatacacat tatgtctact aacctttaaa ataacacgtt
     5161 ttataaaata aaccctcttg acaatattta attttctgat tattctaaat atatacagaa
     5221 agcgctttcc taggatttta tatctaagga ggaagtaaca atgaaaaata aaattattaa
     5281 aattattact tgtctatttt tgttcggtat gattgttgga gcaagtactc cgttaaatct
     5341 gtttcctttt agtgctagag gtataaaagt ggaagctgca agttcacgat ataatcataa
     5401 tcatcgtgga tttacttgct ataaaatgaa ctattatgtt actaataaaa tgtgtagaga
     5461 tttgaaaaaa aattataata agctaaagac tcctgctcaa attgcatctt ttattcctat
     5521 tggtggagtt ggaacatggg ttattacaaa tgcttttagt agtgctgttg atgcaatgaa
     5581 tgtctttgta agagctgcaa atcaaggaaa aggtgtacaa ttaacatata atgctcactt
     5641 tagcaataca acatcatatc aatacaatga ttacgctcgt tatgtaataa aataatcaga
     5701 aagtgaaact atctcatgaa taaaaagatt ttagctgtaa ttatttcaat aatagtttta
     5761 atcactatgt tcttcatatt taggctaatt ttcaatataa gcttacaaaa aagtattctt
     5821 tatctaattc ctatagcatt tatcttagca atttttagaa gtatttacgg aaataaaaac
     5881 tctaaatagc taaaaataaa tcatactaaa ttttacaaaa agtggctagc attttctagc
     5941 cactttttgt attgtggagc gtgggttttg agggggattc aagggggagc ttgcgcccct
     6001 ttgacaagcg gttatttgca ccaaatacgg aggtatttgg ctagcaaata tagagcttgc
     6061 caaacccttt tagtgagttt tgtagaaagt acctttaaag gtactttcac attacgaacg
     6121 atacgtccgt aggacgtact gaaagggtgg gacttatgag caaattaatg caaaatttgg
     6181 ctagcaaaaa agctaaaaaa tatatgctaa taatcgagcg aaataaacac tttttcaagt
     6241 gagcgaatcc gccatgacaa agctgaagca gtttatttca gctttgtcat ggcgtgtgcc
     6301 gactttttta aaagtctagg cacacgagca aatatcttta tcaagctcta atttgcgttt
     6361 taagacgttt gaaacgccta agtatataaa tatataagaa taggtttaag agtgcttaaa
     6421 tcgaatttta gagggcattt agacaatttt agggttgtta gggcttgccc tgaccgcctg
     6481 taaggcgttt taagaacaag ataagggatt tatactagga ctgtcttaaa atgtcttaaa
     6541 cgaacgctca gagcttctca aagggttcct tatgaacggc ttttagcaaa ggagccggag
     6601 gcgactgcgc agtataatgt gagagcagag cgatcacacc tttttagcga accgtaggga
     6661 gcaaggtttg gaattggcag ttttgataaa ttcgcgaacc tgtttagaga aaaaaggagt
     6721 gattttttag gcgggaaaat tagcctcccc tctttttata tctcttttta tatctctttt
     6781 tatatctctt ttatgtcggc tgtgtcctta ctctcccaag caattcagag ttttttcaag
     6841 taggttttct acgcttttca agtaggtttt ctacgctttt caagtaggtt ttctacgctt
     6901 ttcaagtagg ttttccgaca ttattgagta tttttataaa gtatgttact tttatttcat
     6961 actttataaa agtaggagaa gcttatggca aatgaaattg taaaatatga aaatagatta
     7021 aatcatattc ctctgagaaa atttaatagt cgtgaaatga acttattttt ttcaattgct
     7081 tcacgtgtac gtgaaaaagg tgtagatgag attatttttt catttcacga tttgaaaaaa
     7141 ctaagcggtt atacagaacg tggggaacaa tttataaaag atcttagtag cacgtatgac
     7201 aaattattaa gtattaatgc ttggaatgat gatggaaata ctttaactaa atttgttgct
     7261 ttcacaaaat atagcattat acgagataaa caacttgtta taatttcagt taatccagaa
     7321 tttaaaggac tttttaatca attaaagaac tggacaagat ttaatctaga gcaatttact
     7381 aatttggata gcacatattc aaaaactatg tttcgattat taaaacaata tcgaactcaa
     7441 ggctggactg aattttccaa agaaaaattt tttgatttac tagatattcc taaaagttat
     7501 tggaatagtc cgtcaaatat tgacaaattt atcttaaggc caattaaaga agaactcact
     7561 cccttattta aaggattaac tattcgtaaa aaatatggta aaggtcgagg taaacctgtt
     7621 atcggttatc gttttacttg gaaagctgaa attaaccatg ctgacgattt ttccaaaggg
     7681 aaacaagaag atttacgtat aaaattattt aatattgatc acaatggaga attaacacga
     7741 gaagaaaaat ggcgcgctaa agatcgaata ctaaatcttc ccttaggcac tcatgaagct
     7801 gattttaaac aacaacaaca aactgaagaa aaacaggcag aaaaacgaga actttcaaac
     7861 aaactcaaac aagatttact aggaaattta caaaacttat tcgattaagc ttaaggagta
     7921 tttatggcag ataaaacaat caaagaactt gcggaagaat taggagttag taaaacagca
     7981 attaacaaaa aagtttctga caaaaatcga aaactttggt ttgcaaaaaa cggaaacaag
     8041 tttgtgatta acgaaaccgg tcaaaaagct ataaaatcaa tgtttttagt cgataacgca
     8101 aacttaaatc gaaaactagt tggcgaaaaa tcaaaaacca aaaaccataa aaacaccaac
     8161 caagtttccg aattaaaact cctttctttc ctagaaaaac agttaaatcg aaaagatata
     8221 cagctacaag aaaaagataa tcaaataaaa caaatgcaaa aattactcga ccagcaacaa
     8281 caactcactc tacaagcgaa ccaacaaatt gagaacctac aagaacagct ccatttaact
     8341 tatacagaag aaactccaac aaccgaatca actgcctttt ctgaaaaaaa agcagacaat
     8401 acacaaccac ttattgaaaa aaagtggtgg caaatttgga aatctaatag aaccaatctc
     8461 taaaattttc tagaagttag ttcggatagt agaggaaaaa gttgtactac ctgatgggga
     8521 gatcactcaa atttttatga gaaagaaaaa atagtttaca actgtaaaca atcaatgttt
     8581 atagttgtaa actatcaaac tatatggtga cttattgctt aaaataggtt gaaatctcac
     8641 tcaatttttg gtggaaaaac aaaataaatt ctaatcgatt ttgttgaaaa agtcataaaa
     8701 aaacaaatgt gattttaaca aaatttcaaa aaaatcgttt gaaatttcgt ttattttttt
     8761 tgagaatttt gatcatcgta gggtcattgt agaatcatta tgagatcatc gtgggatcat
     8821 cgaataaagt atgggaaagg cttgcggtgc ttggtattaa gggcattctc cgcctcccag
     8881 gttcttgacc attttctctc aacgtggtaa aaatcccact tataagagaa aatggtcaag
     8941 aacctaaacg gtcggcgaag aaaacatacc aagcaccaca agcaaaaaaa gttagagtaa
     9001 cttccaaaaa agaaaaattt tttagaacaa cttttgaaaa tttaattttg atttatatcc
     9061 gttcaattta aacatttgat aaactgaagg ctagtattta aaatgtgtat acaagtggta
     9121 gcgttaaaaa aagtggaggt ataacctatg ttaaaaaaaa ctgtgttggt actgggttct
     9181 atttctctag gaatattagg ttttagcccc atgctattat ccgtaattgg aaa
//
LOCUS       DAPBBR010000088         9126 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.092, whole genome shotgun sequence.
ACCESSION   DAPBBR010000088 DAPBBR010000000
VERSION     DAPBBR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.092"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(101..364)
                     /locus_tag="RD488_002529"
     CDS             complement(101..364)
                     /locus_tag="RD488_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDT7658548.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(463..1758)
                     /gene="rho"
                     /locus_tag="RD488_002530"
     CDS             complement(463..1758)
                     /gene="rho"
                     /locus_tag="RD488_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDT7658549.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(1755..3026)
                     /locus_tag="RD488_002531"
     CDS             complement(1755..3026)
                     /locus_tag="RD488_002531"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7658550.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGTKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(3191..4060)
                     /locus_tag="RD488_002532"
     CDS             complement(3191..4060)
                     /locus_tag="RD488_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDT7658551.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(4352..5962)
                     /locus_tag="RD488_002533"
     CDS             complement(4352..5962)
                     /locus_tag="RD488_002533"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDT7658552.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(7155..8495)
                     /gene="glnA"
                     /locus_tag="RD488_002534"
     CDS             complement(7155..8495)
                     /gene="glnA"
                     /locus_tag="RD488_002534"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDT7658553.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(8523..8915)
                     /locus_tag="RD488_002535"
     CDS             complement(8523..8915)
                     /locus_tag="RD488_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7658554.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         2566 a         1967 c         1565 g         3028 t
ORIGIN      
        1 tttttcagca tcaaacgaag ttttaaattg gcaaaaaaca taaaaaaaca gactatccct
       61 atcagatagt ctgctaaacg ttgagttatc agcgttttta ttattccgca gcgtttgcgt
      121 ctttgagacc gtattttttg ttgaaacggt ccacacgtcc gtctgcttgt gtgaattttt
      181 gacgtccagt gtagaatgga tgtgagtcag aagttacttc gacacggatg actgggtatg
      241 tattaccgtc ttcccattca actgtttctt gtgaagtttt tgttgaacct gacaagaatt
      301 tgaaaccagt tgttgaatcc atgaatacta ctgggtggta atctggatgg atgttttctt
      361 tcatgatttt ttcgctcctt tgccctgctc catttgctga accagagttg atttgtcgat
      421 ttacaacatt aacatcttaa catgtttcag tcaaggttgc aattatcttt tcagatttct
      481 ggtcggattt tttttaccaa aggagacatc ttgaaattct ttgaaaaatt gctgattgtt
      541 ttttgtttta cgcaaaaagc ggatcagttg ttccgtatat tctaatgaat ctccagtcat
      601 attttttcga agtttccaaa tttcttctaa ttcttcactt ggcatcaata attcttcttt
      661 tcgggtacct gattttttga tatcgatggc tgggaagatc cgacgttcag ataattcacg
      721 tgaaagttgt aattctagat ttccagttcc tttgaattct tcatagatca cgtcatccat
      781 acggcttcct gtatcgacta aagcggtcgc taaaatcgtc aaactgccac cttcttcgat
      841 gtttcttgct gccccgaaaa atttcttagg tttatacaat gcggctgggt caatcccgcc
      901 actcaatgta cgtccgcttg gtggaacgac taagttatag gcccgagcaa gtctagtaat
      961 actatccatc aagataacga catctcgttt atcttcgact aaacgcattg cgcgttccaa
     1021 tactaattca gaaactcgag tatggttttg cggctgcaga tcaaatgtag aagataccac
     1081 gtcgcctttc acgcttcgtt ctagatccgt tacttcttcc ggtcgttcat caatcagtag
     1141 aacgattaat tctacttccg gatagttttc ggtgatacca tttgcgattt cttttaatac
     1201 agaagttttc cctgcttttg gcggtgcgac gatcaatcca cgctgaccaa aaccgattgg
     1261 agaaaagata tcgatcattc gggtagatag tctttgcggt gttgtttcca gttgaagctg
     1321 tctttgcgga taaagaggtg ttaaggctgg aaaatgcgga cgttcttttg cttcttccgg
     1381 atcttttcca ttaacgcttt ccacgtgcat caaaccataa taacgttccg attctttagg
     1441 tggacgggct tttcctgcca ctttgtcccc atttctcaaa ctgaatcgtc tgatttgtga
     1501 ggcagaaata tagatatctt ctgcacttgg tccataattg attggccgta aaaaaccgta
     1561 accatcttga ccaacgatat ccaatattcc ttccatataa taaaatcctt gtttctctgc
     1621 ttgtgcacga atcacagcta gagataattc ctttttattc atcttactgt aataaggaat
     1681 tttaaattct ttggcataac tataaacttc ttttaacgtt ttgttctcta gttctgccat
     1741 tgtcaaataa tcgctcattc agctcccact tcctctatca tttcaattga tgcccctaag
     1801 gctgttagtt tctcgataat atgatcataa ccgcgtaaga tataatctac attgtaaatc
     1861 gtcgttgtcc cttctgccaa tagtccagca atcactaaac aagcacctgc ccgaagatca
     1921 gaagccacga cttctgtgcc gtgaagttta tttggaccat tcacgatgat catatttcct
     1981 tccacggtaa tatcagcgcc cattcgtgct agttccggca catggttcac acgtttcgca
     2041 tagatcgtat cgatgatttc tgaagtgcct gtagtcatca atagtaacgc agtaagtggc
     2101 tgctgcagat ctgtggcaaa tcctggataa ggataggtca tgatgtttgc gggttttaat
     2161 tctttcgagg ggtaaacttc gatttcatct tcgctgattt tcatatggac accaatttcc
     2221 tgcaattttg ctataaagct ttccaaatgt tcaaagatca catttttcac tttgatacca
     2281 tttcctactg cagctgctaa tgctagatag gttcctgctt cgatgcggtc aggaatcatg
     2341 aaatgccgac agccatgtaa tgtttcgact ccttcgatac ggatcacatc tgtacccgct
     2401 cctcgaactt ttgtccccat attattcagt aaagttgcca catctatgat ttccggttct
     2461 cgtgcagcgt tttcaattac tgtctgtcct tttgctttta cagcagctaa catcacattg
     2521 atcgttgctc cgactgaaac cacgtccatg aaaatccgat tgccacgcaa tcctttattt
     2581 tctgtccgta aatacatggc accatgttca tttgtcactt cagcacctag agcttcaaat
     2641 cctttgacgt gtaggtcaat cggtctaggg cctaaataac agccacctgg caggcctact
     2701 accgcttcgc caaatttacc aagcagtgtt cccataaaat aataagaagc acgcaaacta
     2761 ttgatttttc cgtgcggcat cggaatcgat acgacttctc gaggatcgat ttctagtatg
     2821 ttgttggaaa aatggacagt tgcgcccatg atctctaaaa tttcaattaa tgaatgaaca
     2881 tcttgtatgt ccggcacacc ttccaagatc actggggaat cagctaagat tgcagctgga
     2941 atcaatgcga ctgcactatt ttttgcaccg ctgatcgtta cttcaccagc taaaggtcgg
     3001 tttcctttga ttacgatttt tttcatctgt ttccaccttg tttattaatc ttttttcatg
     3061 gatatgcttg tattttatca tagataaaaa aaagaaacga gcatggtctg ccgttttaag
     3121 taaaaaagaa tggagagcga cttcaaaagt cgttctccat tcctatatat cgtatctgtt
     3181 atgtggatgc ttacgctttg ttagctgaac cgaaccagtc gatatgagat ttagcatctt
     3241 caacgattgc tgctttacct ggagctaata atttacgagg gtcgaatcct ttaccttctt
     3301 tatctttacc agcttcgata tatttacgag tagctgcagc aaatgataat tggaattcag
     3361 tgttaacatt tacttttgag atacccattg agatagcttt ttcgatttga tcttgaggaa
     3421 tacctgatcc gccatgtaat actaaaggca tgtctggacc tacagcatca gcaattgctt
     3481 gtaagtggtc aaaagctaat cctttccagt tttctggata ttgaccatgg atgttaccga
     3541 taccgcaagc taagtagtcg atacctgtag caaccatttg tttgcattct tcaatatcag
     3601 ctaattcgcc gttaccgatg attccgtctt cttctccgcc gattgaacca acttcacatt
     3661 caactgagat accttttgca tgtgcttttt caacaacgtc tttagctaat ttcaagtttt
     3721 cttcaaatgg tagatgtgaa ccatcgaaca ttactgaagt atagcctaat tcgatacatt
     3781 ccaaagcagc ttcgtaatca ccatggtcta agtggatagc aactggaaca gtgatgttca
     3841 ttgcttcaac taaatcagtg attaaatctt tacagatttt gtaaccaccc atgtatttag
     3901 ctgcacccat tgatgtttgg ataagtactg gtgcttgttt tgcttcagcc gcttcaagga
     3961 ttgcttgagt ccattccaag ttgtttgtgt tgaatccgcc gacagcgtaa ccgcctttac
     4021 gagcagcttt taaaaattca gctcctgata ctactggcat aataaaattc ctcctaagtt
     4081 ttgtaaaact aaatttgtta agacaattct taaccaacga ccctatttta ccaaacattt
     4141 cggtagtttt ctactaaaat caatgaaaat gaaaattttc aagaagtttt ttgcaaaaaa
     4201 taaaatatcc aatagcgctt taatcgaaaa aagtcttttg ctttctatct tttttcctac
     4261 aaataataac aaatcagaaa aagagaaaag tgacaagaaa attgcttatc cccttctctt
     4321 gctacttttc tctttctatc aagttcaaaa attattttgt ttcgtgatct gctaatgatg
     4381 ctccgacaaa tgctttgatt aatttttgcg ggcgatttgg acgagaaatc aattctgggt
     4441 ggaattggca tcccacaaag aattttttct ctggcagctc tacgatttct actaaacggt
     4501 tatctggtga gacacctgaa aagactagcc cttgttcttc aaacaattga cgatatttgt
     4561 tattgaactc atagcggtga cggtgacgtt cttgcacaac atcggctcca tcatatgctt
     4621 cagccgtctt cgttcctttt ttgattttac atgggtataa tccaaggcgt aaagttccac
     4681 ccaaattctc gatgttttcc tgatcagcca ttaaatcaat aatattgttt gctgtatctg
     4741 gattcgtttc agctgatgac gcatcttcta atccaacgac gttacgtgca aattcgacac
     4801 aagccatctg cataccaaga caaataccta aaaacggaac gtcattttcg cgagcataac
     4861 gaatcgcttc gattttccct tctactccgc gatcaccaaa tccaccagga accaagattc
     4921 catctgcgtc tttcaaacgt tcttctacat tttctctcgt taattcttgt gctttgatcc
     4981 aatcgatctc gatgtctgaa ttataggcga aaccagaatg tttcaatgct tcaactactg
     5041 agatatatgc atctggtaac tcgacatatt taccgacaag cgcaatccgt acttttttct
     5101 tcaagttcaa gacacgttct tctaattctt tccattctgt catgtctgct tctggtgtat
     5161 ctagttttaa atggtcgcaa acaatttgat ccattccttg tgcttgtaaa actaatggga
     5221 tggagtaaag tgtatctaca tctggcgact cgataactgc ttctggttcg acatcacaaa
     5281 attgtgccaa tttgtttttc acgctttgag aaacaggttg ctctgtacgt accaccaaaa
     5341 tattcggttg gatacctaaa ccacgtagct cttttacact gtgctgcgtt ggtttagttt
     5401 tcatttctcc agcagctttc aagtaaggaa tcaatgttgt atggatatac ataacattat
     5461 ctgtaccgac atctgctttc atttgacgaa gtgcttcaag gaatggcaaa gattctatat
     5521 cccctactgt tccccctact tctgtaatga tcacatctga atcagtcatt ttagctgctc
     5581 gcatgatttt ttctttgatc tcatttgtaa tatgaggaat aacttgaaca gttgctccca
     5641 agtattcgcc cttacgttct ttacgcaaaa cttcagaata gatttttcct gtcgtcacgt
     5701 tggagtattt gttcaaattg atgtcaataa aacgttcgta gtggcccaga tccaaatctg
     5761 tttcagcacc atcatctgtt acgaatactt ctccgtgctg atatgggctc atcgtccccg
     5821 gatccacgtt gatgtatgga tcaaattttt ggatagttac ttttaagccg cggtttttca
     5881 ataagcgtcc taaagaagct gcaacaatcc cttttccgat tgatgaaacg acaccgccgg
     5941 tcacaaaaat atattttgtc ataagttcaa aaactccttt ttaatttatg tgcaggaaaa
     6001 gtctcagaca ataaacaaag ctccctattc ttcaataaga atagggagcc gaaatttctg
     6061 taaacttctg accctctaaa agggtgccca aggtgtataa tacaagctga ctaagggaaa
     6121 gtcaagtact caaatgaata ctatccgctt acaatttttt ctttttcgat atcctttgag
     6181 aaattatttc ttaagtcctt tatgagtgca aaaaaaattt aacccacata ataagcttga
     6241 tataaacata gctaacgtta aacctaagca aatcagaaaa tcgttactga aaaattttaa
     6301 gtgaaataat agataaaaaa ataaaacaaa cattatgata gataatatcc cacctaacaa
     6361 agaactactt tttcctactt gcagcaacag tttatatagc ttatcgtaga aacaatcttt
     6421 ttctttcacc cttatttacc tcctttacgt aaaaaacgta gtccacagtt ctcggatttt
     6481 tggcatatct tttctattaa ataatatcaa aaacaaaaca attccactaa ttttttcaaa
     6541 gatgaccttt ttttcaacaa aagtgccttg tagggattca ttgaaggtaa cgaatcacat
     6601 aagtaaaaaa taaggagatg cgacaaaagt cgtgcctcct tatttctaaa taaacggtgt
     6661 tctcctgcca actcctcggt cacaagtcac aatatccatc aaacatgaga agctgttttt
     6721 gaaattattt cttgtgattc ggagttaaat ggtaggctca caacctctgg ataaacggta
     6781 ttcaaaagcc agtttctcgg tattaagcca aatttatgca aaaatgtaga aagccatttt
     6841 cacaaaattt ttcttaatac tcgaaactaa acgtcttttt caaaacctct tggtaaacgg
     6901 tgttcaaaag cttgcatctg cggtaataag ttcagccaat tcaaaaacaa gaaaagctgt
     6961 ttttgcttgg ctattcttat tacttgttgc agggcagctt tttcacaacc tctccactaa
     7021 acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaat atgaggaact
     7081 atttttccgt tagtttctct aatactcagg tcaaaacgct gatttcacag cctctaattc
     7141 acggtattcc tgttttaata aagttctaga tattgttctc tttcccactc ggaaacagtt
     7201 tgtctgaatg ccgcccattc gagacgtttt gcttcaacaa aatttgagaa gatatgttgt
     7261 cctaatgcgt caatcattac attatcctta cgcaattctt tgatagcatt atggatagtt
     7321 gaaggtaagt cctggatatg tgcagcttct ctttcttcct catccattac ataaatgtta
     7381 cggtcaacag ctgctggcgg tgtgatctga ttacggatac cgtctagtcc tgcttgcaac
     7441 aatactgcca ttgccaagta tgggtttgca gatggatcaa ctgaccgcaa ttccaaacgt
     7501 gtggataaac cgcgagattc tggtacacgt actaatggcg aacgattacg gccactccat
     7561 gcgacataaa caggcgcttc ataacctgga acgagacgtt tataagaatt gactgttgga
     7621 ttgcaaacgg ctgtgtaggc acgagcatgt ttcagcaaac cacctaagaa atgataagct
     7681 gtttcactta gttccaattc accgtcttta tcatagaaaa catttccttc atcattgaac
     7741 aaagacatat tgcaatgcat accagaacca ttgatcccaa ataacggttt cggcatgaaa
     7801 gtcgcgtgaa gtccatgctt gcgtgcaatc gttttgacaa cgagcttgaa ggtttggata
     7861 ttatcacaag catctaccac atctgcatat ttaaagtcaa tttcatgctg tcctggcgct
     7921 acttcatgat gtgaagcttc cacttcaaag cctagacttt ctaattccaa cacgatgtca
     7981 cggcggcaat tttcacctaa atctgttggt gcaaaatcaa aataaccacc tttatcattc
     8041 aaggtcgttg tgatcccacc gtcttcgtct aatttaaata agaagaattc tggttcaggt
     8101 cctaaattga aagaggtaaa accaaggtcg cgcatatctt tcaatgctcg tttcaaattc
     8161 ccgcgaggat cgccggcaaa tggtgtccca tccggattat agatatcaca aattaaacga
     8221 gcaacttttc catgagcact ttcccacggg aagatcatcc aagtggagag atctggatac
     8281 aaatacatat cgctttcttc aattcgaaca aatccttcaa tcgaagaacc gtcaaacatc
     8341 attttatttt ctaatacttt gtcgatctgg ctcactggaa cttctacatt tttgatcgta
     8401 cctaagatgt ctgtgaacat caatcgtaaa aatcgtacgt tttcttcctc aatgattcgt
     8461 ttgatttctt cacctgttat ctgtttcttt accatggtat ccctcttcct tttttaattt
     8521 attcagtcaa agaattgtct ttgcaatcct tgcgactgat aatgacctgt tttgcttaac
     8581 ccaccttgcg ccaaaatctc atcacgaaaa atttgtcgaa cgtcatgatc tgtcaacggc
     8641 ttcttgtttt ttgcttcttg ttttttcgcc tgtgccattt cgtatacacg tttgatccca
     8701 gccatattca atccctctga aagatagtct ttaatctcaa gcaacatatc aatatcattc
     8761 agcgaataca tacgtcggtt tccttcgctt cgttccggat gaactaaatc ttgttcttca
     8821 taatagcgaa tttgccgagc agacaaatca gtcagcttca taactgtacc aattggaaat
     8881 acggacatag atcggcgcaa ttccttttct cccatcagac gtcccctttc gttttataag
     8941 ttggctaaag tgtaccaatt aaaaaaaata ttgtcaactg catatgttag gttttctaac
     9001 atgagatctc tattttttat aaaataacaa aaaaataaga acacaaaaaa ggtatctagt
     9061 tgattttcgt accagatacc ttttattttt tattatactg tactatcctt tattagtgtt
     9121 tttatt
//
LOCUS       DAPBBR010000089         8228 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPBBR010000089 DAPBBR010000000
VERSION     DAPBBR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.093"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="RD488_002536"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="RD488_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDT7658555.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="RD488_002537"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="RD488_002537"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDT7658556.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="RD488_002538"
     CDS             2591..3376
                     /locus_tag="RD488_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7658557.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="RD488_002539"
     CDS             3389..4240
                     /locus_tag="RD488_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HDT7658558.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="RD488_002540"
     CDS             complement(4364..4816)
                     /locus_tag="RD488_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7658559.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="RD488_002541"
     CDS             complement(5281..5649)
                     /locus_tag="RD488_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HDT7658560.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="RD488_002542"
     CDS             5799..6281
                     /locus_tag="RD488_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HDT7658561.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="RD488_002543"
     CDS             6318..7328
                     /locus_tag="RD488_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDT7658562.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="RD488_002544"
     CDS             complement(7443..8156)
                     /locus_tag="RD488_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658563.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DAPBBR010000090         8067 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPBBR010000090 DAPBBR010000000
VERSION     DAPBBR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.094"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..883
                     /locus_tag="RD488_002545"
     CDS             <1..883
                     /locus_tag="RD488_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDT7658564.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            931..3060
                     /locus_tag="RD488_002546"
     CDS             931..3060
                     /locus_tag="RD488_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDT7658565.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3035..3724
                     /locus_tag="RD488_002547"
     CDS             3035..3724
                     /locus_tag="RD488_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658566.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4132..4818)
                     /locus_tag="RD488_002548"
     CDS             complement(4132..4818)
                     /locus_tag="RD488_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7658567.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4954..5148)
                     /locus_tag="RD488_002549"
     CDS             complement(4954..5148)
                     /locus_tag="RD488_002549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658568.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5198..5638)
                     /locus_tag="RD488_002550"
     CDS             complement(5198..5638)
                     /locus_tag="RD488_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDT7658569.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5642..6487)
                     /locus_tag="RD488_002551"
     CDS             complement(5642..6487)
                     /locus_tag="RD488_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDT7658570.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6636..8054
                     /gene="pepV"
                     /locus_tag="RD488_002552"
     CDS             6636..8054
                     /gene="pepV"
                     /locus_tag="RD488_002552"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDT7658571.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2481 a         1515 c         1713 g         2358 t
ORIGIN      
        1 tatttcagta ccggttgcac tgttctcatt tatgggctcg attatggctg gaatctttgc
       61 taatatcgtc aatttcaaac aatatcaaac gatttatgct ggtttcaatc cagcggctga
      121 aagctatact tataatgact atttccaaat tggtatgatt gggatgattg taagcttagt
      181 tgtggtacta acggtcgcta atatatcaat gaacaaaaag aaacgctatg caatggcagc
      241 aaacgtacca gctgaaggtg gcgacgcacc aatgatctca tggttagccg tattattacc
      301 agttttaggg gtcgttcttt tagatcttca aatcatctta ggttttattc tagcaggtat
      361 ctgggcattg ctgtttactg gaaaattgcg cggaggttat aaagaaatct gtcgtcagtt
      421 tgcgaaatta tttacagatg gcgcagtcga tgttgcacca atggttggtt tcttgatgac
      481 cttagcgatg ttcaataatt cagctgcgta tgcttctcct tatttttcag ctatttttgg
      541 agattggata ccgcaatcac cattagtctt ggcaatcgta tttgctatat tgacaccact
      601 aggatttttc cgcggtccaa tgaatctagt cggttcaggc tcagctattt tagctgtcgt
      661 gttagctgtt aatccaacga tgtcgccagc ctttttgttc ccgttatttg caattacaac
      721 gattgctcct cagcatttag atattacaca atcttgggtt gcttggggat taggttatac
      781 aaaagtaact tctcgagaat atatgaagaa atccatccca actggttgga tcatcggtgc
      841 gatcttatgc ctgatcacgt tcttattgta cgggaacgcc tagtaaacaa aacgtcgata
      901 aaaacgatta gataaatgga ggaaaagaaa atgaaacgtt ttgtgcgaat gggaattgat
      961 gttggcggta cacatacgaa agcagtcgca atcgataatg cgacgcacga aatcatcgga
     1021 aaatcttcag tgaaaacaac ccacgatgat gtccgtggag tagctgcagg tgtcgttcag
     1081 tcttttcaaa attgtttgcg ggaaaataat atcagtccag aagatgttgt gtttgttgca
     1141 cattctacca cacaagcgac taatgcactg attgaaggag acgtagcaaa agtcggcgta
     1201 atcgggatgg caaaaggtgg attagaaggt tttttagcaa aacgacaaac tagattgaac
     1261 gatatcgatt tagggaataa gaaaaaaata gagattgtca atgcattctt acctgtcaaa
     1321 aacttaaatg tagaccgtgt ttcagaaacg atttcttctt tagaaagaga aagagcggag
     1381 gtcttggttt cttctatggc atttggagta gataatgggg aaccagaacg agttgtttat
     1441 gaagcagcat ctgtgaaagc gatccctaca acgatggctt ctgacatcac aaaattatat
     1501 ggattgacaa gaagaactcg gacagcagca atcaacgcat ctattttacc aaaaatgcta
     1561 gatacggcaa cctcgacaga agactccgta cgagaagcag gggtcaatgt ttctttgatg
     1621 attatgcgcg gagacggcgg agtaatggaa atcaatgaaa tgaaaaaacg acctgtttta
     1681 accatgcttt ccggtcctgc tgcatcagtc atgggctctt tgatgtactt gagagcgtct
     1741 aatggtgttt attttgaagt aggcggaaca acaaccaata tcggggtcat taaaaatgga
     1801 cgtccagcaa tcgattattc aattgtaggt ggccacccaa catatatctc ttcattagat
     1861 gttcgggttc taggtgtggc aggcggttcg atggtacggg ctaatcagtc aggaatcatc
     1921 gatgtcggtc cacgttctgc acatattgcc ggtctagatt atgcagtatt tacggagaca
     1981 gaaaaaatca aaggtcctaa ggttgaattt ttctctccta aagaaggaga ccctgctgat
     2041 tacgtcaagg tagtgatgga agacggagaa gaagtgacta ttacaaatac atgtgcagcc
     2101 aatgttcttg gattagtgca agaagaacat ttttcttatg gaaatgtccc atctgcacga
     2161 aaagccatac aggcattagc agactattgt catacgacgg ttgaagacat cgcagagcag
     2221 atcatggaaa aatcctatgc taagattgaa ccggtgattt tagaattggc agacaagtat
     2281 cacttggaga aagatcagat ttctcttgta ggtgtagggg gcggcgctgc ctcattgatt
     2341 acttacttta gtaataaaat gggtgtgaaa tattcgattc ctgaaaacgc cgaagtgatt
     2401 tcttctattg gtgtagcact tgcaatggtc cgagatgttg tagaacgtat catcccttcg
     2461 ccaagtaaag aagatatacg atcgttgaaa aatgaagcga tgaataaagc gattgaatca
     2521 ggcgctacac cagaatcgat cgaagtccac gtagaaatcg atccacatac ttcaaaagta
     2581 acggctatcg ctactggttc tacggaagtg aaagcaaccg atctaaccaa ggagatcaca
     2641 acagaagaag cactagagct tgctgcagag gatatgcgat taaataaaaa tgaagtttgc
     2701 ttattggaaa atacaccttt cttttatgta tgcggcgaac agaatcgttc aaaaaatgct
     2761 ggaagtcttc ggatcatcga tcaaaaagga tttatcaagg tccaacgtgg acatgcttca
     2821 tgtatgaaaa caactgcagc caattatatg acagctgtcg aacaactttg ggaagatatg
     2881 gcagtttatc aaactgaatt gattgcccga ccagaatttt atctctgctt aggagcaaga
     2941 gtctctgatt ttacagcgac ggatctggaa caactacagc ttttgatgga tctggaagta
     3001 tctactatgg aaccggagga agaagtgatc gtcgttgccg gaaatatcaa acaaacataa
     3061 gttagaagag ttactaaacg aattacaaca gatccccgaa gaaatttggg gattctacca
     3121 gtttcggcga gatttatttt ggaaaaagat tcctttgtcc aagcagaaaa ttcttataca
     3181 acaatcaatc gattgtggta tcgaaacggc atgtagcatc aaaaaaaagt acccttttgc
     3241 cgatgtagga gaaatctgtg aacaaatggc tgttccaatc gtttcctgtg aatcagagca
     3301 aataaacgaa cgaatcactt ttgcaactta tgcagaagat gaagggatcc gattgatgac
     3361 ggagccgtta gaaaaattaa aatgttcagg actagcttcg atctctaaag aaacagcgca
     3421 agctttgatt attggacatg aactatttca ccacatcgaa gcttctgtta agggaattta
     3481 tacgcaaagc gaaaaaattg tgctgtggcg gttgcctttt tatacacatc aatcaaacat
     3541 tcgtgcattg agcgagatag cagcgatgag tttttcaaaa gagatgaatc aaagcgattt
     3601 ttcgccttat gtattagagg cagtcttact ttggccatat aatgaaattc gtagccaagg
     3661 gatcttagaa gaaataaaag aaatagaaaa aagatgtacg gagtatgatt tagattacaa
     3721 ataaagagac tgtgacaaaa gtcgtgtcac agtccttttt ttccgaataa acggtgttct
     3781 cctgtcaact cctcggtcac aagtcaaaat attcaacaaa catgagaagc tgttttttga
     3841 aattgttcct tgtgactcgg agatgaacgg caggctcacg acctcttgga aaaaggtgtt
     3901 caaaagcttg catctgcggt aataagaaca gccaagttaa aaacataaga agctattttt
     3961 acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctc aataaacggt
     4021 gtgcaatcag ctgaccctcg gtattagctc aaaaaaaacg gcaaaatatg aggaactatt
     4081 ttgccgttta tttctctaat actcaggtca aaacgctgat tccaaaacct cttatttgat
     4141 gggtctgtcc tgaatatctt caaaataatc ggggtaatta tgaatcacgt attcttgctc
     4201 ctcgataatc atatgtaaat gcatcgtgca aagaaatccg acttcatcaa agttatgatc
     4261 aatcattgat tgaagcattg tctgatgttc atctaatact cgaccccagt ctaattctga
     4321 aatcgtcaaa cgtaaccatc tgaaacggtt caagtgcgta ctataacttt ctagccaatc
     4381 ccaaatttct cgttttccag caatttcata acaagttcgg tgaaaatcag tatccaaatc
     4441 aaaaaaagct tttttatttt gagcgatcac tgcctgatcg gtttgttcta gtattttttc
     4501 tagtttagct tgatcttgct tggtcatttt cgcactgcat tcttgcagga tcggtttttc
     4561 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     4621 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     4681 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     4741 tccgggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     4801 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     4861 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     4921 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttggatcgg
     4981 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     5041 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     5101 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     5161 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     5221 aagcgtacgc ttggaataac tgttctaact ccggattgac tttgctcagc ttcactaatc
     5281 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     5341 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt tcccgtatac ttttggatag
     5401 ttgggtggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     5461 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
     5521 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
     5581 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
     5641 ctcatgcctc gttttccatt gattttttac aaaaataatt catccacttc ggaagtgctt
     5701 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
     5761 tatgaagata aacagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
     5821 ctgtgatcat cccagctaaa gtgtcaccca tgccgcctgt tgccatagca gcagaaccta
     5881 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
     5941 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
     6001 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
     6061 agggtagcaa aagatgatta gcaacaagta aacttaaagc agagccatca atcaccagcc
     6121 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
     6181 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
     6241 cagtatccgt ccaatctaca atcattgctt ctggcagatg actgtgaaga gcactccgat
     6301 ttttttcatc agttactaca gtcgtgagac ccgctccact gtgtacggca gctaaagcac
     6361 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
     6421 ttcctttatg tgaaatcttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
     6481 tcagcatcga aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
     6541 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
     6601 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
     6661 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
     6721 agcgcgatga ttcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
     6781 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
     6841 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
     6901 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
     6961 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
     7021 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
     7081 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
     7141 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
     7201 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
     7261 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
     7321 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
     7381 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
     7441 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
     7501 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
     7561 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
     7621 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
     7681 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
     7741 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
     7801 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
     7861 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
     7921 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
     7981 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
     8041 gtttggcgaa ataaaaatac taaaaaa
//
LOCUS       DAPBBR010000091         7925 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPBBR010000091 DAPBBR010000000
VERSION     DAPBBR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.096"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            4..1305
                     /locus_tag="RD488_002553"
     CDS             4..1305
                     /locus_tag="RD488_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658572.1"
                     /translation="MENSAFIMKLNDILSPIAAKIGNQRHLKAISSGMMFGLPFIVIG
                     SFFLIFANPPINIDKYNPDTANIFMKFMASWKDFAVANYDLITAPYNLTMGIIGFISV
                     FGIAFSLANEYKINPSMNGMVASVIYLMVCTPVEEGAINLNFLGTNGLFVAIIIGLLV
                     VEINRLFEVKNIKLKLPDTVPPMVATFINMLVPLLTNIFIFYGINLIFLAATNKIFPE
                     AVMEVLTPATNIAGSLGGFLLIVTLGNILWLFGINGSSIIFPIVFTLGMAQTGLNAEQ
                     LANGETMTHLMNLQMFRISVLGGAGGTLGLVLLMMRSKVPEYRTIGKLSLVPGICSIN
                     EPVIFGLPIVFNPILAIPFLITPIISLLLTYFAQQLGWIGIGFIVDPSFTPFFAQAYL
                     SSMDWRNILFCLLLIVISIFIYYPFFKVMESNKTKLVDEKL"
     gene            1704..2894
                     /locus_tag="RD488_002554"
     CDS             1704..2894
                     /locus_tag="RD488_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7658573.1"
                     /translation="MNYFTTSLMKNLFSNDNNLPAFEQAVTELFRSELEKSLNEILAY
                     ELTDFLDYEPYARTNNENSRNGSYQRKFDTKYGTITLNIPRDRMGEFFTSLLPKYRRR
                     DLFTETTILDLFEEGMSHSEICSMIQKLCGARYSKQTISNITDKALECVDSFKNRILN
                     KEYAIVYLDGTSMPLRRDTVSREMVHIALGITVEGTKEILGYMIAPNESAEIWEELLK
                     DLKSRGVERISLFCTDGLSGMENVIQDIFPGSKIQRCLVHIQRNICAKVRVSDRKEVA
                     NEFKEVYRSKSKEEALTSLKKFIDRWKHKYPSMVKSLSNNDYLFTFYDYPESVRHTIY
                     STNLIEGNNKQLKRSFKKKEQFPTEKSEEKYLVIQFNRYNEKNMNHVHRGFGQTTRED
                     WFKS"
     gene            3063..3485
                     /locus_tag="RD488_002555"
     CDS             3063..3485
                     /locus_tag="RD488_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658574.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            3495..3698
                     /locus_tag="RD488_002556"
     CDS             3495..3698
                     /locus_tag="RD488_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658575.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            4039..4653
                     /locus_tag="RD488_002557"
     CDS             4039..4653
                     /locus_tag="RD488_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658576.1"
                     /translation="MRVAYIRVSSIDQNEQRQVEEMKKFGAERIFIEKQSGATITHRP
                     VFQEVLDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSTVNHE"
     gene            complement(4677..5027)
                     /locus_tag="RD488_002558"
     CDS             complement(4677..5027)
                     /locus_tag="RD488_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7658577.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(5021..5284)
                     /locus_tag="RD488_002559"
     CDS             complement(5021..5284)
                     /locus_tag="RD488_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HDT7658578.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            complement(5625..5804)
                     /locus_tag="RD488_002560"
     CDS             complement(5625..5804)
                     /locus_tag="RD488_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658579.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQKLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            complement(6249..6686)
                     /locus_tag="RD488_002561"
     CDS             complement(6249..6686)
                     /locus_tag="RD488_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658580.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            complement(6702..6953)
                     /locus_tag="RD488_002562"
     CDS             complement(6702..6953)
                     /locus_tag="RD488_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658581.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            complement(6953..7159)
                     /locus_tag="RD488_002563"
     CDS             complement(6953..7159)
                     /locus_tag="RD488_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HDT7658582.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     QTCGKKYTLSYGDYVLIDEKGKKH"
     gene            complement(7602..7862)
                     /locus_tag="RD488_002564"
     CDS             complement(7602..7862)
                     /locus_tag="RD488_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658583.1"
                     /translation="MDKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
BASE COUNT         2558 a         1426 c         1317 g         2624 t
ORIGIN      
        1 tatatggaaa attctgcgtt tatcatgaaa ctgaatgaca tacttagccc catcgcagcc
       61 aagataggta atcagcgcca cctaaaagct atatccagcg gtatgatgtt tggcctaccc
      121 tttattgtta tcggttcttt ttttctgatt tttgcaaatc cacccatcaa tattgataaa
      181 tacaatccag atacagctaa tattttcatg aaatttatgg ccagctggaa agattttgcc
      241 gtagcaaatt atgatctcat cacagcccct tataatttga caatgggaat catcggattc
      301 attagtgttt ttggcattgc attttccctt gccaatgaat acaaaattaa tccttccatg
      361 aatggcatgg ttgcatctgt catttatcta atggtttgta caccagtgga agaaggtgcc
      421 atcaatctta atttccttgg gacaaacgga ttgttcgtcg caattatcat cggcttgcta
      481 gtagtggaaa tcaaccgact atttgaagta aaaaatatta agttgaaact cccagataca
      541 gttccaccca tggtagcaac ctttatcaat atgctcgttc cactgctgac aaatatattc
      601 atcttttatg gcatcaatct gattttcttg gcagcaacaa acaaaatctt ccctgaagcg
      661 gtgatggaag tcctgactcc agcaacgaac atcgctggca gtctaggtgg tttcttattg
      721 atcgtgactt tgggtaacat cctatggcta tttggtatca atggctcgtc aattattttc
      781 cctatcgtct ttacattggg aatggctcaa actggtttga atgctgaaca actggcaaat
      841 ggtgaaacca tgacacactt aatgaactta caaatgttcc gtatttctgt acttggtgga
      901 gccggtggta ctttgggttt ggttttattg atgatgcgaa gcaaagtacc cgaatatcgc
      961 acaattggaa aattgtcatt ggttcctgga atctgttcca tcaacgaacc agtgattttc
     1021 ggattaccta tcgtttttaa ccctattttg gcaattccat ttttgattac gcccatcatt
     1081 tcattattgc tgacctactt tgctcagcaa ctaggatgga ttgggattgg atttatcgtc
     1141 gatccttcct tcacaccttt ttttgcacaa gcttatcttt caagtatgga ctggcgcaat
     1201 attctctttt gcctactgtt gatcgtcatc agcatcttca tctactatcc attttttaaa
     1261 gtcatggaga gcaataaaac aaaattagta gatgaaaaac tatagtcgtc attcttaacc
     1321 ttgtaacgaa aatatggttc tatactattt agtgttgatg ggaaatctta gggtttccca
     1381 tcaacctatt ttttataaaa aagtatactc tggtgtccca caacaaataa aggaagcgcc
     1441 cttgttcaaa aggctacttc ctttattttt attttgcttt aaattttgag tcatcattta
     1501 taagcgaacg taagagataa tagacaccta aaaatagaaa gaaaaataaa ggtaatacac
     1561 gtagtaaaac aaatggagtt tcaaaaataa atggatagca taaaatatct tgtgtaaatt
     1621 cgtttttcta gaaatgtaga aaaaaaggta tatccttagt aaaattagtt cgaccaaaaa
     1681 caatttacga aaggaatata cccatgaact attttactac atctttaatg aaaaacctat
     1741 tttctaatga caacaatctt ccagcttttg aacaggctgt aaccgaactg tttcgttcag
     1801 agttggagaa atctctcaat gaaatactcg catatgagtt gacggatttt cttgattatg
     1861 aaccatacgc tagaaccaat aacgaaaatt ctagaaatgg ttcctatcaa agaaagtttg
     1921 atacaaaata tggaactatt acactcaata ttccaagaga tagaatggga gaatttttca
     1981 cttctcttct gcctaaatac agaagacgag atctatttac cgaaacaacg attttggatt
     2041 tatttgaaga aggaatgagc cattcagaaa tttgttccat gatccaaaaa ttatgtggag
     2101 ctcgctattc taaacagacc atatctaata ttacggacaa agctctggaa tgtgtagatt
     2161 ccttcaaaaa cagaatattg aacaaagagt atgccattgt atatcttgat ggaacatcca
     2221 tgcctttacg ccgtgatact gtatccaggg aaatggtcca tatagcacta ggaatcacag
     2281 tagaaggtac aaaagaaatt cttggctata tgattgcacc aaacgagtcc gctgagatat
     2341 gggaagaact tctgaaagac cttaaatcaa gaggggttga acgtatttct ttattttgta
     2401 cagacggatt gtctgggatg gaaaatgtaa tacaggacat tttcccgggc tctaaaattc
     2461 aaagatgcct ggtccatatt caaagaaata tatgtgcaaa agtaagagtc agtgacagaa
     2521 aagaagtggc caatgaattt aaagaggtat atcggtccaa atcaaaagaa gaagctttaa
     2581 cttctctaaa gaaattcatc gataggtgga aacacaaata tccatcaatg gtgaaaagtc
     2641 tcagcaacaa tgactatctg tttacattct atgattatcc agaaagtgtt aggcatacga
     2701 tttattcaac aaatctgatt gaaggaaaca ataaacaatt aaaacgaagt ttcaaaaaga
     2761 aagaacaatt tccaacggaa aaatctgaag agaaatacct tgtgattcag ttcaatcgtt
     2821 acaacgagaa aaacatgaat cacgtacata gaggttttgg acaaacaacc agagaagatt
     2881 ggttcaagag ctaatctgct ttaccaagga tatactttta cacaaaatta ttgacgctcc
     2941 caaatttaaa cgattatgac attaaaaata tattttatga attttctagt atataacttg
     3001 atttatctgt taagatttat taagaaaacg ttttcttatt tttgatttcg aggtgataga
     3061 caatgaaaaa taagtttatt ttatctttag gtattttaac tattggaatt agtgtaactg
     3121 gaactacaat tcctacattt gctgatagta caaatgaacc aactactgta gtagataata
     3181 accaagaatt aactccttta gataggaacg gaatagccat tggtaaccca actaacgact
     3241 taactgttac tgaaaattat ttaatagttt ctccattact tgctcgagca gcttctaaaa
     3301 cgatacgagt gacaggaacg atgatttttg ataaagttgg ttggccttct agacctcctc
     3361 aatcacggaa ttggaaagaa aaaagaaatg gttattggta ctatggaaaa ttgtatttac
     3421 aaagttataa atcagctgga aacaattgga ttgcgactta ttcaggaacc ttaactagaa
     3481 agtagggatt ttttatgcca gaatttgtga acacaccaaa tttttatcaa gatagcgata
     3541 ttctaagtaa aattaattta ccgaaagaag aatcagcttt acaagttcag cgaactttac
     3601 aggagacaca aaaaattcaa aaatcaattt ctaatctaga agattctgaa gaaaaaagaa
     3661 aaaaaagaga ccaaaaaaca tatcaaaaag aaaaataatg attttaaaaa aagagtgtct
     3721 agtcgacatt ctttttttct aattgaaagt gttcataaaa tcacccattt ctggacactt
     3781 tctgtcattt ttatatttaa ttggcacagt tttttctaat tatttgtcat attcatagtc
     3841 aactatagct acaaaagcaa ctaattttgg agatagattg agatatttaa aaatctatca
     3901 tgaaaaatta gttgcttttg tcacttagcg ctgaaaattt atgccattta tctagaaaaa
     3961 tgacaaacat tgaaaaatct ggttttctca tgtatgatta gggtgtgttt taaatagttg
     4021 cagaaagtag gtaaaaattt gagagttgca tacatacgtg tctcatcgat cgatcaaaat
     4081 gaacaacgcc aagttgaaga aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa
     4141 caatctggcg ctacaattac tcatcgacct gttttccaag aagtattgga ttacgtccga
     4201 gatcaagata tttttattgt ggaagctatt gatcgacttg gaagaaatta cgacgagatc
     4261 atcgcttcag tcaattactt gaagaagaaa aatgtgcagc tgatcattac aagtctaccg
     4321 atcatggccg aagcaattgg caatcctctc ctggataaat tcattaaaga tttgatcatt
     4381 caaattttgg ccatgatcgc tgaacaagaa cgtaccgaat ctaaacgacg tcaggcacaa
     4441 ggcattaaga ttgcgaaagc gaacggtgtt tataaaggac gtcctaagct atacagtgcc
     4501 aatgcaaaag atccccaacg tcgtcttgtt tataaaaaca tcgttgagga tctaaaaaaa
     4561 ggtgttgcga tcgctaagat tgcaaaagac tacaatgtta cgagacaaac cgtatataga
     4621 ataaaaaaag acagcacggt caatcacgaa tagttgatca tgctgctgtt tctattttat
     4681 ttgcttactt tttgaaaaac tgttctaact ttcatcaata actcctcaac taaactatca
     4741 tgcgcttttt ccaaaaaaat acactctctg gcttcataat caattgtcgt tagttgatct
     4801 aataatactt ttcctgttgt cttcatttca tattctgagt ttatatttac atatagcgga
     4861 tagtttctag ttgtactaga aattggagca actgtaacaa cgttactata atccgcaata
     4921 atatcatgac ttaaaacaat ataaggcctt ttacctgtct gttcgtgtcc agatcgaggt
     4981 gctgtattca ataatagaat atcgccttgt ctaggttttc tcaccatttt tcattaccta
     5041 ctgcttcacc taaattttga atcgtcacat gatttctttc atcagtgtaa ttttcaaata
     5101 actgttcaat tgttaattca ttttctatat tagccgcttc gataattagc cgcttctgac
     5161 cgtttacttc ttcttgtatt atcttcactt tgtcttctgt atgaattcca agatattcca
     5221 taatatactt tggcaatcta aggccattac tatttcccca tttttttata ggtaacattt
     5281 ccatagtaga cacctctttc tgtatataca tagtataaca tacataagaa aaaacgtata
     5341 tacttaatta tccttttcta ttaaattaga ttaacattcc atgaatccat aaactatgtt
     5401 aacatttata tgaaaatagt cgaaaggaaa tcataatatg tttaagaaaa caaaatcttt
     5461 agaatcaggt aagaaaaaaa ttgatctaaa aataatctct tctggatact ttaaagattt
     5521 catagttatt gatacaaaat ggaataaaaa ggatatagaa aatattctaa atagtaggaa
     5581 caattaagtg ctatcacttt tgtttcttca aatgaaaagt gacgtcactt tttgagtgct
     5641 ggtacatcaa atcctgcttt ttcttgcgcg atcaatagat ctaacgcaat acacataatc
     5701 ttagattcac tttttccgta cttctgcttt agtttctgca attctttttg tctcttttca
     5761 tccaacgtaa cgggtaaccg tttatttcct attgcaattg gcattagtac tctctccttt
     5821 catcgaaata accctatgaa aaatatggct gcaatcaact tgaatattag actcacaagg
     5881 gctaacacaa agcgccaaaa gattaaacaa aacaccagta ttaccaaaaa tactacgaag
     5941 tttaaatgca cagctgcact atgtcgcata attatttcgc caacaaatag tactaacaat
     6001 aagggaataa tcttgttcaa atggatcacc ttctttctct tgagttatcg ggctttgccc
     6061 gtttatttcg catcacctaa gcggcggggg cggttggagc gattggtgcg aaataagaac
     6121 cattccctta gttactaggc tttttttgtc cttatttcac acattctcac ttttcggtat
     6181 aaatgattat tgaccttttt ttctttcaaa tcgttgatat ggaatccgtt gttagttgat
     6241 aaatcacctt attcattttc gttgtcttcc tttttcatgg tgtaatatgc gccatactta
     6301 ttgatatttt caaaataatc taaccattca cttgaaacag tcttggcttt tttcgtttcg
     6361 ataaatttcg catacgttag ttctaaagct tggtattcag aaggtttgat tgtgcttggt
     6421 ttgacgccta cttccaagca tagtaaggct tggaaaaacc attttgcatt ttgctttttc
     6481 agttcttcca gtgttcgata gtacgtcgca atgagattca tttcgacacc tgattcaatc
     6541 atttcttcca cagctaccga caatttttct ttataatgtt tctttggaac acgtgtttcg
     6601 ttgtatagga acgtcatatc ctccattttt tgtgccattt tatccaaagg taatttgaca
     6661 aattcgtcat agtaattttg agccatattt ttttctcctt tttagttctc taatttggtt
     6721 aaccaatatt cgttttcata agtttccatg ttttcttgat aatgcagttc atatcctgca
     6781 atcttcacta ggtcttcaaa tagcatagtc ggtgcatcct ctactaaagg ggtttctatc
     6841 gtccagtacc gcggaataag taaagcttct gctacttttt cagaaatgac ttctttgtcc
     6901 accaaaattt gaacgacttc ttttacagtc aataatttgt gttgtgtttt catcagtgtt
     6961 tctttccttt ctcatcaatc aaaacataat cgccataaga caaggtatat tttttcccgc
     7021 atgtttgaca ttgatacaaa cgatagcttt tgatacattt cgctctttct ccacaatcgc
     7081 attcgacagt atgtggtgca tgatagtttg ggaataattc gctgaaggga acaccccaat
     7141 aatcaaattt ctttcgcatg attgattctg cctcctctta ggaaagggtt tacttccttt
     7201 cgttagttct ttctttattg atttgttggc cagaatgaat caacgaaaag cgacaaggac
     7261 aagggcgcgc agcgtgccat ttacccttgt ccttgtcgct ttttggtgat aaaaggcaac
     7321 ttgttgccgg tctggcaaat caataaagag atagcgaaca ggaacgaacc ttttggtgag
     7381 aggaagtttt tcctattttg tcttgctttg caagacccct tatcttagtg aacgtgcaac
     7441 gttcacttcc tttcttctcg aacggcggtg gcggttggag tgagagaaag gtttttcaat
     7501 tgagaaggcg cttgtgcctt cctaaacagg ccttttcctg ttcccgtttc tatgtaaaac
     7561 aaaaagagct gcaatcctca tttaggacta caactcttct tttatatgcc catcgatcgc
     7621 gtaaaatgat cgggatttct aacatacatg ctagcaataa ctagctgatt tcgtttattg
     7681 aagtgacctg tgacggcaat attgtatttt ccatcatcca taattagcag tttatcgata
     7741 atttcaatat ctgcaactac acaattaatc gattcatgaa ttgtttgtaa agtaaagcga
     7801 accaataatg gttgtgtttt tattactcgg attttatcaa gcaaaccaac atatttgtcc
     7861 atcacaatca cctcgctaaa attatagcaa aaacaaccaa aattgagaat ttttattcga
     7921 tttta
//
LOCUS       DAPBBR010000092         7605 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPBBR010000092 DAPBBR010000000
VERSION     DAPBBR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.097"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            80..946
                     /locus_tag="RD488_002565"
     CDS             80..946
                     /locus_tag="RD488_002565"
                     /inference="COORDINATES: protein motif:HMM:NF012376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HDT7658584.1"
                     /translation="MITLKNHKLELLQFTDIHIGQAPFNEEDQKTFAMIDQTLAKTTA
                     DLIVITGDLIWSDGVIEPTKGLEALAEIFNKYPIPLAITYGNHDSEETIDRHDLHELE
                     KKLFNHLALKANQFFDPNQKECFTIEIKDDNQLVNVLYFIDSGANALIDYESYDWVSL
                     EQIKWYDETFAKYQKINHTKDLLFLHIPLPEYLQAGERIVEGRFWEMNPRISAPKLNT
                     GLFSHLLENNHLLGTFCGHDHDNNFEGIYLGQRLIYGNVTGYNCYGDLPRGYRKITLK
                     PDQMTTSIETFE"
     gene            complement(1116..1544)
                     /locus_tag="RD488_002566"
     CDS             complement(1116..1544)
                     /locus_tag="RD488_002566"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658585.1"
                     /translation="MLKCYGEAELLEMLKRNEFEEDSPIRSVEDLLGHLDQASPMMWV
                     TVYVPEVQSVYGIHRETLISTGQSHRSTSKPVALLEATGYQTSEHVFVSELAALLQME
                     VVPKNREIFELQLFERKRGKYMLRRWQMIGDQPVLIAQRG"
     gene            complement(1563..2027)
                     /locus_tag="RD488_002567"
     CDS             complement(1563..2027)
                     /locus_tag="RD488_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658586.1"
                     /translation="MNEPDMTNQFRVGEVILQRMIDRKEFEDIYRSVTRKNTVDAYYF
                     DAGRRIVTVFAYYLGSISGSSVDEERIVGELMALMATMERDSIPGVVVWDKISKLPGT
                     PEHSMQLASEKAIEDTFTFLLAAAKAEEPYYLNGGTETIVSMIAAEVEQDCR"
     gene            complement(2101..2409)
                     /locus_tag="RD488_002568"
     CDS             complement(2101..2409)
                     /locus_tag="RD488_002568"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658587.1"
                     /translation="MDKSKEIIFMPDYLVKDHTVLVLDSANNLHGFLSIESTDDHFVF
                     TNDIDLLKTVPKIIAEELATDIRASEGDYIPVTNKDTGEVSELGSDDLQIVFSAVEWC
                     "
     gene            complement(2434..2685)
                     /locus_tag="RD488_002569"
     CDS             complement(2434..2685)
                     /locus_tag="RD488_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658588.1"
                     /translation="MVKFEDQPKQGYTGIRTLETIASVFEDIQASGDMGQGEKNLRYL
                     QLMNELEEDHGAMIVNPTKTDLNLPAVALYRKVSQARVF"
     gene            complement(2678..3130)
                     /locus_tag="RD488_002570"
     CDS             complement(2678..3130)
                     /locus_tag="RD488_002570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658589.1"
                     /translation="MICRYCNKKVLKLEGGQYHCANCELDFFENQLIEFRSGLYREPT
                     VETDPFFFQYTTTKELLQMTYVELLSRLKLARGVYRELRKKVYGHNSQADDLDRENLK
                     AVTSAKLVIENIMIEKHGYYPASVFESVIDKEVLKNKKQMREVEKKHG"
     gene            complement(3284..3511)
                     /locus_tag="RD488_002571"
     CDS             complement(3284..3511)
                     /locus_tag="RD488_002571"
                     /inference="COORDINATES: protein motif:HMM:NF037117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658590.1"
                     /translation="MRKTISLTSNNIKVSGHIGTWYVYASRVYHGRRLFLVEHETYGD
                     HAANLILDKTGNCVMEDVWNGWEDYEVYIES"
     gene            complement(3609..3821)
                     /locus_tag="RD488_002572"
     CDS             complement(3609..3821)
                     /locus_tag="RD488_002572"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658591.1"
                     /translation="MDALRKLEVTLYNKQWFTLIGIEACLKNQDGFSAEEVLDQIQGC
                     LEEYKHVEGAMMEEYQQQNFAKLETV"
     gene            complement(4473..5798)
                     /locus_tag="RD488_002573"
     CDS             complement(4473..5798)
                     /locus_tag="RD488_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HDT7658592.1"
                     /translation="MKIAYDYPFKPLTPPKGFFKWCSSQITGYRWANKERTIVSTTRP
                     EAPIISKRLTKASNLNRSERCYPFALVLSSKTRVEIQSFGIWVGIENGVETYEIARTN
                     LECFCNDVHYQQHYFRNKWYGGLLNHGYMTGSYTNTQFYPNKWREKLAKNSPLKYCNL
                     KDISWYHLAHAYKYRREIEFLKLIHADKFADDMLFSAMHVIRDRVRGKSIDYRTVNMK
                     WLRKHKGILKNSTITFCEMRLKEAIRKCHGKPIAGIEEILTVEDLKRIPTCVGLTSFQ
                     KWAVAQDLDFGMYVDYLNMLDELGIGVDKENAMPKEFRAAHDEKAKLVGVKENKEYEK
                     EFNERVLQLKGLEKRLGDVQIVAPKEMGEMLVEGQNLRHCVGGQYYIRRHAKGETTIL
                     FVRKADKLDEPYLTLEMRNHRIVQLRGKRNQAAPPEIEQIIEKWVKTAN"
     gene            complement(5804..6655)
                     /locus_tag="RD488_002574"
     CDS             complement(5804..6655)
                     /locus_tag="RD488_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658593.1"
                     /translation="MVKASQQNAKNSAFGYCCVAQRPKGAKTMKNGTIKRMADLKSAL
                     REENQKKQLSIFDETLGYAAIDFRIDHQQKGERSISWVTLIAAPSVKMKTVGEFLERL
                     EVYPDQTVVATVGLEGGYSPVHLAMDGLGKETWLVLCDEIAYHNFFSPPEHSELEVEF
                     DLKGAVKEHLKIQLETSKNPTETRLAGWLEQQEDSELLIGVLKEEKSLSELVQFCIQK
                     ASASKGKQSAMMVSDEVVFQWVREYYTTDIEMKNSSSVKGTMQTTPTPQVIETERKEE
                     EQQISLF"
     gene            complement(6846..>7605)
                     /locus_tag="RD488_002575"
     CDS             complement(6846..>7605)
                     /locus_tag="RD488_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HDT7658594.1"
                     /translation="HTSCDDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVV
                     ADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKELLSKNEFLYDEYFDCYICPQDQMLA
                     FSTVTREGYREYKSNPKECVNCPLLNQCTKSKNHQRVITRHVWGDLMDEVEHLRLTDL
                     NKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWK
                     GKEPLFFCSKIRNEVDKKLFQDRVTSLEQLLSTV"
BASE COUNT         2049 a         1783 c         1387 g         2386 t
ORIGIN      
        1 ttaaaaaaag ttattaaagc gtttgcatta ttttttgata gggtttattt taataacgta
       61 ttaagaaagg atgttaccct tgattacttt aaaaaatcac aaacttgaac tattgcaatt
      121 taccgatatc cacatcggtc aagctccttt taatgaagaa gatcaaaaaa cttttgccat
      181 gatcgatcaa accttagcga agacaaccgc tgatttgatc gtgataaccg gcgacttaat
      241 ttggtcagat ggtgttattg aacctacaaa agggttagaa gctttagccg aaattttcaa
      301 taaatacccg attccattgg caatcactta cggcaatcac gactccgaag aaaccattga
      361 tcgtcacgat ctccacgaat tagagaaaaa actcttcaat catctggctt taaaagccaa
      421 tcaattcttt gatccaaatc aaaaagaatg ttttacaatt gaaattaaag atgataatca
      481 attagttaat gttctttatt ttatcgattc cggcgccaat gccttaattg attatgagag
      541 ctacgactgg gtttctttag aacaaatcaa gtggtacgac gaaactttcg cgaaatatca
      601 aaagattaat catacaaaag atctattgtt cctccacatt ccattacctg aatatctaca
      661 agccggcgaa cggatcgtag aggggcgttt ttgggaaatg aatccgcgaa tttcggcacc
      721 aaagcttaat accggcttat tcagccattt actagaaaac aaccatttac tcggcacttt
      781 ttgcggtcat gatcatgata ataatttcga aggcatctat ctgggccaac gattgattta
      841 cggaaatgtc accggttata actgttatgg cgatttgcca cggggctacc gtaagatcac
      901 cttaaaaccg gatcaaatga cgacttccat cgaaactttt gaataaagaa agaacagcta
      961 gtaatctgct agctgttttt tatgtagcaa aatcagtcct aaaatagtca ttcattttag
     1021 gactgattct aatttaatta gtagttgtcg tttttgttgc ttttcatcca ataaaggtca
     1081 cctcagctta cacaacactc atctttaaat aataattagc cacgttgggc aattagtact
     1141 ggctgatccc caatcatttg ccagcgacgc aacatgtact tcccccgttt tcgctcaaac
     1201 agctgtaatt caaagatttc tcgattcttg gggactacct ccatctgtaa aagcgccgct
     1261 aattcagaaa caaagacatg ttcacttgtt tgataacctg tcgcctctaa caaagcaact
     1321 ggcttagatg tactcctatg gctttgtccc gtagaaatca acgtctctcg atgaataccg
     1381 tacacacttt gaacttctgg tacatacacc gtcacccaca tcattggact ggcctgatcc
     1441 aggtgtccaa gcagatcttc aacactccga atcggtgaat cctcttcaaa ctcgtttctc
     1501 ttaagcattt ctagtagctc agcttcacca tagcatttca acatattttc tgcctcctgc
     1561 tgctacctac aatcctgttc tacttcagca gcaatcattg atacgatagt ttccgtccca
     1621 ccattgagat aatacggctc ttcagccttt gcagctgcaa gtaaaaaagt aaaggtgtct
     1681 tcgattgctt tttctgaagc aagctgcatg gaatgttccg gtgtgcctgg aagttttgaa
     1741 attttatccc aaacaacaac accaggaata ctgtcgcgct ccattgttgc catcaaagcc
     1801 ataagctccc caacgattct ttcctcatcg actgaagaac cagagatact tcccaagtaa
     1861 taagcaaata ctgttacgat tctacgccct gcatcgaaat agtaggcgtc caccgtgttc
     1921 tttcgggtca ctgagcgata aatgtcttcg aattctttcc gatcaatcat tcgctgaaga
     1981 atgacttccc caactcgaaa ctgattcgtc atatccggct cgttcattaa tttctacctt
     2041 cttttctcct attagttgaa tccatgcatt catcatgatc gttagactca gccgctacct
     2101 ttagcaccac tctaccgcag aaaatacgat ttggaggtcg tctgaaccca attcagatac
     2161 ttcgccagta tctttatttg ttactggaat atagtcgcct tcagaagcgc gaatatcagt
     2221 tgcaagttct tccgcaataa ttttcgggac ggttttgagc aggtctatat catttgtaaa
     2281 aacaaaatga tcgtcggttg attctatact caaaaaaccg tgaaggttgt ttgctgaatc
     2341 taaaactagc accgtatgat cttttactaa atagtctggc ataaagatga tttctttcga
     2401 tttatccatt cgtaaactcc tctcaagttc cgcctaaaat actcgagctt gagaaacctt
     2461 ccggtataat gcgaccgcag gcaaattcag atccgtttta gtcggattca caatcatagc
     2521 tccgtggtcc tcttccaact cattcatcag ctgcaagtat cgcaaattct tctcgccctg
     2581 tcccatgtca ccgctggcct gaatatcctc aaatacactc gcaatcgttt ctagcgtccg
     2641 gatacctgta tacccctgct tcggttgatc ctcaaattta accatgcttt ttttccacct
     2701 ctcgcatttg ttttttattt ttcaaaactt ctttatctat aacagactca aaaacgctgg
     2761 cgggataata gccatgtttt tcaatcataa tattttcgat gacaagcttt gctgaagtga
     2821 ctgccttcag gttctcgcga tccagatcat ctgcttggct attgtggcca taaacttttt
     2881 tcctcaactc acgatagacg cctctcgcca gcttcagccg agacagcaat tctacatagg
     2941 tcatctgcaa taattctttt gtcgtcgtgt attggaaaaa gaacggatct gtttcgacgg
     3001 tcggttctcg atacaatcca gacctgaact caatcagttg gttctcaaaa aaatccagct
     3061 cacaattggc acagtgatac tggccccctt ctagcttcaa aaccttttta ttacaatatc
     3121 gacaaatcat cacaaatccc cccgttttca caaatagtat atcatgctaa ataaacaatg
     3181 ctgctcttct tttttaccaa gaattagcct acaagaacat acccaagctg aagactctca
     3241 gcttaggtca tcctaagatc agactggtgc ctactctttc ccttcagctt tcaatataca
     3301 cctcataatc ttcccaccca ttccaaacat cttccatgac acagtttccc gttttatcca
     3361 gtatcaagtt ggcagcgtga tccccgtagg tttcatgttc tacaagaaat aaacgacgtc
     3421 cgtgatacac tcgactggcg tatacatacc acgtacctat atgcccgctt accttgatat
     3481 tgttcgatgt taatgaaata gtttttcgca taattcaaca ccctttcaat gattccggaa
     3541 aacaacctgg caaggaccag gtcgtcatcc gaattacatg ccttgcattt ccgattgttc
     3601 agctggtatc acacggtttc caacttagca aaattttgtt gctgatattc ttccatcatt
     3661 gccccctcaa catgtttgta ctcttccaga caaccctgta tttggtccaa aacctcttca
     3721 gcggaaaaac catcctgatt tttcaaacaa gcctcaatcc caatcagtgt aaaccattgt
     3781 ttgttgtaaa gtgtgacttc caattttctt aaagcatcca tgtaaaaaac tccttttttg
     3841 ttggtttgaa acccattttt ttaggagcta gggcggagct ggaatcttta aagaaattcc
     3901 aattttggtt tgtccagtcg tgccctttgt tcctatttgt catgggttca ttttttccag
     3961 tgtgcttagg tcgtttgctg tggttatgct ctagatcggg cccggtggca ggtaaagggc
     4021 ggcggatttt gccgcttgta taccctttac ctgccaccgg gtttgatcta taaccacaaa
     4081 cagcaaacaa cctttgcaca caaaatgaaa ccggaatagg agcggcgatt gacgaacaaa
     4141 acaaaattcg ctcggaattt tcaggcgggt gatttccccg ccgtcttgcg agaagtcgga
     4201 gctatgcttc gagcaagacc tttcaatcct tttgcttttt tgccctggca aaaatgactg
     4261 aatcggctga cttggcggag gaacgcagcc aaccaaagca actgcgactg gcgaaggcac
     4321 gtagccatca agcggttaga ttctgtcact aggcaaaaga agactgtcgc gttttgagcc
     4381 aagggcaact gcaccgcagg cgaagcgcca gttttacccg ataagcggct taccagaatg
     4441 ctgtgctttt catcactctg gtaaacgtct tatcagtttg cggttttaac ccatttttct
     4501 attatctgtt cgatttcagg aggtgccgct tggtttctct tcccacgcaa ttgaacaata
     4561 cggtgattcc tcatttctaa ggtgagatag ggttcatcta acttgtccgc tttccgaaca
     4621 aagagaatcg ttgtttctcc cttcgcatgt cttctaatat aatactgacc accgacacaa
     4681 tggcgaaggt tctgcccttc caccaacatc tcgcccattt cttttggtgc aacaatttga
     4741 acatcaccta gacgtttttc aagccctttc aattgcaata ctcgctcatt aaattctttt
     4801 tcatattctt tattttcttt aacgcctacc agttttgctt tttcatcatg agctgctctg
     4861 aattcctttg gcatggcgtt ttccttatct acaccgattc cgagttcgtc taacatgttg
     4921 aggtagtcca catacatgcc aaagtcaagg tcttgtgcaa cggcccattt ttgaaagctg
     4981 gttagcccaa cgcatgttgg tatacgtttc aagtcttcca ccgtcagaat ttcttcgatt
     5041 ccagctattg gttttccatg acactttctg atagcttcct ttaatcgcat ttcacagaac
     5101 gtaattgtag agtttttcaa aattcctttg tgtttccgaa gccatttcat gttaaccgtt
     5161 cgatagtcga tacttttccc tcgtacccta tcccgtataa cgtgcatagc cgaaaataac
     5221 atgtcgtccg caaatttatc cgcatgaatg agttttaaga actcaatctc ccgccgatat
     5281 ttataggcgt gggcgagatg gtaccaagaa atatctttga gattacaata ttttagcggt
     5341 gaattttttg ccagtttttc tcgccacttg ttgggataga actgcgtatt cgtgtatgag
     5401 ccagtcatgt aaccatgatt cagcaaccct ccataccact tatttctaaa ataatgttgc
     5461 tgataatgta catcattgca gaaacattca aggttcgttc gagcaatttc ataggtttcg
     5521 acaccattct caattcctac ccaaatgccg aaagattgaa tttcaacacg agttttgcta
     5581 cttaacacga gcgcaaaggg gtaacagcgt tctgatctat tcaaatttga agcttttgtc
     5641 aatcgcttgg aaataatcgg ggcttctggt cgtgttgtcg aaacaattgt ccgttctttg
     5701 ttcgcccagc gatagcccgt aatttgcgaa ctacaccact tgaaaaaccc tttcggtggc
     5761 gtgagtggtt taaatggata atcgtatgcg attttcatag tagttagaac agactaatct
     5821 gctgttcttc ctcctttcgt tctgtttcaa tcacttgagg tgttggtgtg gtctgcatgg
     5881 ttcccttcac tgaacttgaa tttttcattt caatatcagt cgtgtaatat tcccttaccc
     5941 actgaaaaac aacctcatca cttaccatca tagcggactg ctttcctttg cttgctgaag
     6001 ctttctgaat acaaaattga accaattcgg atagggactt ttcttctttt aagacaccaa
     6061 ttaataactc agaatcttct tgttgctcta accaacccgc aagccttgtt tcagttgggt
     6121 ttttagacgt ttctagttgt atttttaggt gctctttcac tgcccctttc aaatcgaatt
     6181 caacttccag ttccgagtgt tcaggtggtg agaaaaaatt gtggtaggca atttcatcac
     6241 agagaacgag ccatgtttct ttccctagac cgtccattgc taaatggacg ggtgagtagc
     6301 caccttccag tccgactgtc gcaactactg tttggtcagg atagacctct aatcgttcca
     6361 aaaactctcc cacagtcttc attttgaccg aaggtgccgc aatcaacgtg acccacgaaa
     6421 tacttcgttc acctttttgt tggtggtcga tacgaaaatc aattgccgca tatccgagcg
     6481 tttcatcaaa aatcgagagc tgttttttct ggttttcttc cctcagtgca gacttcaagt
     6541 ctgccattcg tttgatagta ccgtttttca tggttttcgc tccttttggt ctttgcgcta
     6601 cacagcagta gccaaacgct gaattttttg cgttttgttg cgaagctttt accatgcagc
     6661 agccaggcgg caagggtgcg tagcacattg cttgcccttg ccgcctggcg aagccacttg
     6721 cgagaaatag aatgagtagg cgcagcctgg aggctcattc tatttcgtag ctagtcggcg
     6781 tctgcaatgg taaaaatgta gcgcaaaacc aaaaaattca aatagaggaa cccggcacgg
     6841 gttcctcaga ctgtagacaa aagctgttcc aaactcgtaa ctcgatcttg gaacagcttt
     6901 ttatctactt cgtttcgaat ttttgaacaa aaaaataaag gctccttgcc tttccatagc
     6961 caggtggcta atttctttaa attcattgca gcaaacacta gcatcgtatg cgtcgcgact
     7021 ttttccaagc ctcgatactt ggtccaacgc atcccatgct tttcttttgc atccgcgaat
     7081 attcgttcaa tcgtttgttt ccgttttttg taaattgatt tattcagatc tgttaggcga
     7141 agatgttcca cttcatccat cagatctccc caaacatgtc tcgtgatgac tcgttgatga
     7201 tttttacttt tggtacattg gtttagcaga ggacagttca cacattcttt tggattggat
     7261 ttgtattctc ggtacccttc tcgagtaacc gttgaaaaag cgagcatttg atcttgcgga
     7321 caaatataac aatcaaaata ctcgtcatag agaaactcat tttttgataa tagctccttt
     7381 ttccctttgg gccttgaata aggcaaacaa ggtcgaaggt tcaaatgagt caaaaagtga
     7441 acaaacttag gtgtcttata cccagcatca gcgacaacac aattgatttc aggaaaaagt
     7501 ctcttcgatt gtttgacgag ctgaaaggcg acttgactgt catgaatatt tccaggagtg
     7561 atgattgtgc taagaataaa tccattgtcg tcgcatgaag tatgg
//
LOCUS       DAPBBR010000093         7600 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPBBR010000093 DAPBBR010000000
VERSION     DAPBBR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.098"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(943..1356)
                     /locus_tag="RD488_002576"
     CDS             complement(943..1356)
                     /locus_tag="RD488_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDT7658595.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="RD488_002577"
     CDS             complement(1812..2297)
                     /locus_tag="RD488_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658596.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="RD488_002578"
     CDS             complement(2436..2651)
                     /locus_tag="RD488_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDT7658597.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="RD488_002579"
     CDS             2875..3675
                     /locus_tag="RD488_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7658598.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="RD488_002580"
     CDS             3694..5562
                     /locus_tag="RD488_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7658599.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="RD488_002581"
     CDS             5555..6046
                     /locus_tag="RD488_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDT7658600.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="RD488_002582"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="RD488_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDT7658601.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="RD488_002583"
     CDS             6606..>7600
                     /locus_tag="RD488_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDT7658602.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAPBBR010000094         7590 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPBBR010000094 DAPBBR010000000
VERSION     DAPBBR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.099"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(83..1114)
                     /locus_tag="RD488_002584"
     CDS             complement(83..1114)
                     /locus_tag="RD488_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658603.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(1121..1951)
                     /locus_tag="RD488_002585"
     CDS             complement(1121..1951)
                     /locus_tag="RD488_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658604.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAKTGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(1948..2763)
                     /locus_tag="RD488_002586"
     CDS             complement(1948..2763)
                     /locus_tag="RD488_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7658605.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDILSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(2760..3584)
                     /locus_tag="RD488_002587"
     CDS             complement(2760..3584)
                     /locus_tag="RD488_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDT7658606.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(3574..4674)
                     /locus_tag="RD488_002588"
     CDS             complement(3574..4674)
                     /locus_tag="RD488_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7658607.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4852..5637
                     /locus_tag="RD488_002589"
     CDS             4852..5637
                     /locus_tag="RD488_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HDT7658608.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            5670..6053
                     /locus_tag="RD488_002590"
     CDS             5670..6053
                     /locus_tag="RD488_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDT7658609.1"
                     /translation="MSNLRDYNQEAPIHCLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            6129..6260
                     /locus_tag="RD488_002591"
     CDS             6129..6260
                     /locus_tag="RD488_002591"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7658610.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            6229..6465
                     /locus_tag="RD488_002592"
     CDS             6229..6465
                     /locus_tag="RD488_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7658611.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(6543..7514)
                     /locus_tag="RD488_002593"
     CDS             complement(6543..7514)
                     /locus_tag="RD488_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDT7658612.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         2175 a         1812 c         1508 g         2095 t
ORIGIN      
        1 aaatcaattc taccttagat gttcttatat cactctatca gtcctatttg acaaagagcc
       61 agaaatgttt gccgactata cactagcttt gttgtgcaaa atgctgagta tcaatttcca
      121 cagggattgc tagaatatct ttcagctgaa tgtataaggc atcgctaatt ttctcttccc
      181 gatcgttcaa ccgatccact aaaatttctt tgccctccag cgtttgaaaa acataccgtt
      241 gaatgttgcc taaaataaat gattccttcc atagaaccgg aatcttaacc ccctgaggaa
      301 ccggttcaaa ttgaatcagc tccggtctta aataataaat gcagcgattg cccttagcgg
      361 aaaactcgtg ggtatactga ttcagctcat accattcgaa acgattatag ttgccgataa
      421 attccgcaac aaatcggctc tgaggattct gatacaattc cttcgaggtg gaaacctgag
      481 ccacccgccc agcttccatc acaaaaatcc gatcactgat tcgcatcgcc tcttcttggt
      541 catgagtcac aaaaatcatc gtcatcccta gcgattgctg gatagcgcgc aaatcccgct
      601 gcagctgttt tctaattcgg gcatccaaag cacttaatgg ctcatccagc agcaggactt
      661 tcggttcagt gaccaatgag cgagccagtg ccacccgttg tcgttgaccg ccagaaagaa
      721 actggacatt tttatctgcc tgctccgtca tatccaccaa tgatagcatc tcaaaaacct
      781 tttcctgaat cacctcagga ctcagcttct ttaccttcaa accaaaggct acattttcaa
      841 aaacagtcat agttggaaac aatgcatact gttgaaaaac aaagccgata ttgcgatcct
      901 tcgtaggctt atcggcaata ttctcattgt ccagcacaat ctcaccgctc tttggttgtt
      961 ccaatcccgt gatacagcgc agcaacgtag actttccgca cccgctggga cctagtaaag
     1021 taaccagctc acccttttca atctgaattt catcaatagc taaaatctgt ttttcatcaa
     1081 aaaacagatt gagatcatgt atttctaaaa acattttccg tcacaactcc tttaagggct
     1141 tctttttcga ctgcttctct tccctcgtct gcttaaggga cagctgttgc ttttgtcgat
     1201 aagtcagcat aaaggtagtt aaagcaattc ccaccataaa cagcaaatac aaaaccatca
     1261 cagcgctagc caaatggccg ttttcgttca tccgccgcag catatagatg cgtaccgtct
     1321 gaaatcgacc gccaatcaac aggttcgtca gcatgtactc cccaaaaacc gaagaaaaaa
     1381 tcatcagaga aactagggtc acaccgatac ggatgtttgg aaacagcacc tggataataa
     1441 tcgtagacat cggggcgccc aaggtttctg ctgcatccac taattccttc agattaatta
     1501 agcgcatctg gttgttaaga ctaagataga caatcggcaa cgccgtaata aacaatgcac
     1561 ctaccaacac tacaaacatt gggataccag ttttagcata cgttcgaagc aaagccgtta
     1621 ccaaaatcac tcctggtaaa gcatacggca gcaggagcag cttttccagc caacgattca
     1681 aacgagggaa atacaaatga atccaaataa tggtgggaat catcaacaac agaatcgtca
     1741 ccaagaccac acctgctaat aaaagtgagc gacccaccgc agcaataaat tccctgtccg
     1801 tcagcagctg ttggaaccat tgcaaggtaa aatcactagg taaaagcgat tttgaccatt
     1861 tagtggagct ggcatacaaa atcgttccaa taatcggcag caagtaatac aggacaaagc
     1921 agaacaaaat cggttttatt aactttttca cgtctgcacc accttgcctt tcttttgaat
     1981 aatcaacatt gccgttacca gcaggacacc taaagcgact gccaacgcac tgcctaaatt
     2041 aggcttggcg aacacatctc ccgacactaa agccgcaatt cgaatcgtta aaagatttac
     2101 attactgctg gtcagggcat acgctgtttc ataggtcccc atgccattag caaataagat
     2161 gacaaaggtg ctggcaatcg atggtcgcaa aaaaggcaaa gccaccttga accaagcata
     2221 cgctgatgaa gcgcccagca attgtgcgga ctccagccat tcctttttca cttccttcat
     2281 gctgggatac aaaaacaaga cccctaacgg aatttggaaa taggtatacg tgatggtcaa
     2341 tccccaccaa gaatacaaat tgaagtccgc tagaaatggc aaaatcattt tcagcacacc
     2401 tacattcccc aacaaaataa taaaagagaa tgccagcgga atcccagcaa aattagctgc
     2461 caaattggaa acaaaggtga ttttctcctg caatttagtc gatagattca ttaagcataa
     2521 acataaaata aacgtcccga ttaacccaat cacactggag ctgacagcaa tcagtacgct
     2581 gttaacaaag gcctgtgtgt aatatttgtt gcttaaaata tcactgtaat tggccaatgt
     2641 ccactggtta gttaaatcac tgtgcaagct gcacagaacc ataaaaagca gcggcagcag
     2701 taaaaatgca cagaagataa aggaggcagg aaccagaacc aagcgttttt tcatctcttt
     2761 catcccctca tcaattcttg aatgtcctgc attttctctg acggtgcaat tcctaataac
     2821 cagcaaaaca atggagccgc cagcagctgt ggtacagttt gttccttcag cttttggcgt
     2881 ttatttgaaa tcaaataaaa aggaacttca cgatgtgcag ccaagctgcc gccatgcagt
     2941 ccgtgcgcat ccatcccgtg atccgcagtc accacgactt gataaccttt ttgcagccat
     3001 tcaggaaggt aaatagccaa taatctgtcc gcctgattaa ccgctgctgc atattcatga
     3061 gaatcggcgg taaatttgtg accgacatca tcaatattca tcgaatgtac gaccaaaaag
     3121 tctggctgat actgattcac taaataatgg gcatccgcaa ataaatgcga atcagggtaa
     3181 gtgtcctcac tataaaagat gccatgctga atcagtcgct cctcctgatg ctggatgcga
     3241 tcaaccaaac gattataggg ggcttgattg tacaactcgc tgtaccagtg gtaagcggcg
     3301 gctcctgttt ttccgccagc ttccttaact aattcaaaca gcgaccactc tttggatcgc
     3361 tgagcatggt aattactata gatgccattt tcataggctg gaacgccggt catcagtact
     3421 tcgtataacg gacgtgaatt gctgggcagc tcacttttta ccttcaataa gcttgcttgc
     3481 tggtgctcaa ctaaatgatt catgaaccca agctgggcga cggctgtgtc gtagcgacag
     3541 ccgtctagta taactacaat cagtttgtca agtctacttt gcataggtca gtacctccgc
     3601 ctgccaaagc tctggaagct ctacagaggt cttgttccaa gcttcattgt cttcaactgg
     3661 caccgccgct tcataagcat cctccggcag taatttttca gctacttctt taggcagctc
     3721 taccttgcga ataggtcgcg catagccctt tgccaaattg atttgccctt catcagataa
     3781 aatatattcc cgtgctagct ttgccgcatt gggatgaggg gcatttttat tgattaaggt
     3841 tgtatacccg ctaatgatgg agccgtctgt tggcacagtt acctcaaaac gctcggagtc
     3901 aatttggtca cgataattta gtccattgaa gtcccaaaca actgccacat cgatttcacc
     3961 tttttcaaga tttgctacgc tggcatcaac ggtggacaaa cggccttttt ctgccatttt
     4021 tttgtagtaa ttcagacctg gctgaatatc cttttcgtca cctccgttgg caatcgccgc
     4081 agccaataca gcaaattgtg cttggttggc aatcgtcaca tcccccacgc taacttgata
     4141 gtcaccctct tgcagctcct tccagctagt cggtgcttgc ttcacattct ctttatcggt
     4201 gataaaggaa atggttcccg tatagcttaa caaccaatcc ccatcatcat cctttgccca
     4261 atccggaatt tcctcccaat agttggtctt ataaggtaag gttaactctt tgctttcagc
     4321 caacggaccg aagctgatac cgacatcacc aatatcggcg gttccatttt ttccttctga
     4381 ttcaaactta gccaattctt ctgcactgga catatccgta tccacgtgac ttaagccgta
     4441 ttctttttca aggtcgttcc aagtgcctac ccaatttgcc caagtatccg gcattcccaa
     4501 gctggcaatc tctccttctt ccttggcttt ttctataatc gtatctaaag agtcgtctgc
     4561 cgcagccgat tgcttcgttg cttcacctga gccgcagcct gtcagcagga tacttactgt
     4621 tgctgcacaa aataaaccga tagtcatgtt acgaattttt tcattcattt tcattcattc
     4681 ttctcccctt tcgataattc cattctaaca aagctttgta atgagagaat caatttcttg
     4741 aaaaggtttc atgaacaatg taaaggttgt atatggtttg taaatttcga cgaattcccg
     4801 ttaaccttct aaagcttttg cggtatgata gtagaaaaaa ggaggatccc tatgcagtat
     4861 tatgatcagc atctccacac gtatttttcc tttgattcag aggaaaaatt tgaaaactat
     4921 ttagcctatc agccggagtt tttcgtttct acggatcact ttgatttaaa caatccatct
     4981 accggaaaag atgacattcc ggattatcca gcctatataa acaaactgga ctctttaaaa
     5041 gaaacctatt ccaccaaatt tctgcgaggt atcgagattg gcgttgttcc aggacaagaa
     5101 gagcggatcg tggattacct cgctcagcat ccttatgatt taaagctggt aagtattcat
     5161 caaaatggcc gctttgatta tatggacgat gtggttttaa ccaaagatcc cattcaaact
     5221 accaaggaat attttgatca gatgttgcag gtcttgacgg attttccaga aggagatatt
     5281 ttgactcact ttgattatgg attacgccgc ttcaccttca cagcggaaga attcgcggag
     5341 cattttgagg ctcagctgct aacgattttc aaaaaggttg ttgaacgaga attggcgatg
     5401 gagttaaatg ccaagagctt cttgaaatac ggcaacgaag acctttaccg ttatgccgtt
     5461 cctttgtatc aaagtgtcgg cggaaagctc tttaccttag gctcggatgc tcatgttgcc
     5521 gaagattatc agctgggctt taaaaaaatg agtcagctgt tggcagactg tcaggtagaa
     5581 aagttgctag tcattcaagg aaaagaacgc cgcctgacgc cgctgccgat tttgtgattc
     5641 ctatataata gaagaaagtg gtgaaaaaaa tgagcaacct gcgggactac aatcaagagg
     5701 cacccatcca ttgtttaatt gcgcgacatt gggatgcgtt gaaaattgag gcggtttgcc
     5761 gatccttgtt agcagccgtt ccaaaacaac aactggaaaa ttttttggtg gctgacagct
     5821 tgcagcggga aaaagttcag gcttattttg cagcctttaa agatcagcct ttggaatatt
     5881 tgcatgcgca gtttcatctt ttttatcaag tagccgcccc agatgactac aacgatttac
     5941 gaggacagct gcaattgacc tttcaagcgg atgaaaccgc ctataccgtt ttattgggaa
     6001 tggctcgcct tggtgatcag gcgaaggtcg agtggcggat tttcgatatt tgatggcagg
     6061 atcaaggcgt ttcagttgca aaccttcctc tctttcaatt agaaaaaccg cagcaggaag
     6121 aagtttgtgt gctggtcacc gatgctggtg aaattcgtct ccgcttattt cctgaccaag
     6181 ctcccctggc tgtagccaac tggcgctccc tagctgagca aggcgtttat gacaacacac
     6241 ctttcggctc gtgtcattaa ggaatttgtt attcaaggtg gcgctttgga tggttctggt
     6301 gatgaagctg tttccagcta tgagggcttt ttcgctgatg aagtgcatcg cggactttat
     6361 cattttaatg gcgccttggc cttaggggac cacggccccc acaccaacgg caaccagttt
     6421 tttattgtgc aaaacacaaa ggcgcaggct gacctgctaa tgtaaagcaa gcatacttgg
     6481 agcttggagg actaccggag ctggatggtc gttatactgt ttttggataa gtataccaag
     6541 ggttagaaat cgtagcagcg atcgcagctc agccgacaaa cagtgaagat gtaccgattg
     6601 agccagtgtt cattcgacaa attaacttcg aaaaaacatc gtaaaaagac actcacagac
     6661 ttcagcaaaa gctctattct tgagctggct gcagctagtg agtgtctttc atttatccat
     6721 aagataaagc ttggattcaa taaataaata aatgttttgg ttaaagctgt gaccagcaaa
     6781 tgaggaaccg tgcgagccag ttgatctgcc aatgcaaaca tttctttagg tgaaggcgct
     6841 ggcgtgtctg ccaacggata ctccagtccc aatgcttggt aaccgtgcat accatagcag
     6901 tggtacggta gtaattctaa cggtacgaac cgatcaagat ctgccacaaa acaagcaatc
     6961 gtcagcagct cggtcaggtt catattgata cctggaacca caggaactcg aattcgcact
     7021 tcgcagttag gatactcaat taaaaagcga cgaatattct tcaaaatttg ttggttatct
     7081 aagccggtcc attgtttgtg gagcttgctg gtaaacattt ttacatccac aaacaatgta
     7141 tccacatagg gagctacctt ttggatttca ttataagcac cacaaaagct ggtttccagt
     7201 acggtattga ttccaatgta tttcgatttt tgcaaaattt ctttagcaaa atccgcctga
     7261 accagtgcct cgcctccgct aatggtcact ccgccatccg agtgaaagta aaaaacagca
     7321 tccttctcaa tctcatccat tacctcttca gcggtcatgg tctggccaaa tcctttttca
     7381 atctgcttgc tttgtgattc gggaatcgaa caccaggcac agcgtaatgg gcagcccttt
     7441 aaataaacaa cggtccgtaa accagcacca tcatgtagag aaccctgttc tattcttaat
     7501 actgttcctt ccatatagat ttttgaatta cacactagtt taaactaaaa cacacaagga
     7561 aaaacttacc atttaatcat aaaattagct
//
LOCUS       DAPBBR010000095         7159 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPBBR010000095 DAPBBR010000000
VERSION     DAPBBR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.100"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            24..1316
                     /locus_tag="RD488_002594"
                     /pseudo
     CDS             24..1316
                     /locus_tag="RD488_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1835..2569
                     /locus_tag="RD488_002595"
     CDS             1835..2569
                     /locus_tag="RD488_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7658613.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            2585..3754
                     /locus_tag="RD488_002596"
     CDS             2585..3754
                     /locus_tag="RD488_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7658614.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            3770..4765
                     /gene="lacD"
                     /locus_tag="RD488_002597"
     CDS             3770..4765
                     /gene="lacD"
                     /locus_tag="RD488_002597"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7658615.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            4844..5770
                     /locus_tag="RD488_002598"
     CDS             4844..5770
                     /locus_tag="RD488_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7658616.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            5789..7039
                     /locus_tag="RD488_002599"
     CDS             5789..7039
                     /locus_tag="RD488_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7658617.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDANRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2349 a         1194 c         1470 g         2146 t
ORIGIN      
        1 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gccgaaaagt
       61 tagctgaatc cattctgaat gcctatcaac ctgaatctgt cgatgacatg caagatgctt
      121 tgaaagatgt gtttgggccc ctttttgaaa aaatgcttca aggagaattg aataatcatt
      181 taggttatga tgcccattct aaagagccta aggaacacga taaccgtcga aatggctatg
      241 gaactaaaac gcttaaaacc agttttggtg aagtagctat tgatgttcct agagaccggg
      301 aagcttcctt tgaaccagag ttaattccta agagaaaacg agatgtctcc gacatcgaag
      361 ggaaggttct ttccatgtat gcacgaggaa tgagtcaatg agatattgcc gcaaccgtcg
      421 aagctattta tggctttgat atttcccatg aaatgatttc agatatcact gacgctgtcc
      481 ttcctgaatt ggaagaatgg caagcccgcc ccctagcaaa gtgttatgcc tttctattcg
      541 ttgattgtat gtatgttact ttacgagaaa attatgaagc caaagaatat gctgtacaca
      601 ccattcttgg ctatgatctc aaaggaaata aggagatttt aggattatgg ttaaatcaaa
      661 cagaatctaa aaatcgctgg atgcaagtat ttgatgaact gaaagcacgt ggtgtcgaag
      721 atgtcttttt catttcgatg gacggtgttt ctggcctcga agaaggcgca aaagcgatct
      781 ttccatcggt aattgttcag cgctgtattg ttcatcttgt tcgaaatgca ttgcgctata
      841 ttccaagtaa ggactataag gaagtctgcc gagatatgaa aaagttctac ggtgcttctt
      901 ctctaaacgc tgcacatgct gcttttgaca gttttcaaaa tcggtggtct cattattctg
      961 gtgctgtaga tgtctggaaa cggaactttg cacatgttga acaactattt gattatggta
     1021 gtgccattcg aaaaattatg tacactacca atgcggttga aagtgtccac tccagcttca
     1081 gaaaagtcac aaaaaaagga gcgttctcta atgagaatgc actcctaaaa ctactttatt
     1141 tacgcacgaa agaattacac gcgaagtggt caggtggtcg aattcaaaac tgggctatgg
     1201 tgcttaatca gttaatgatc aacgagacct tctcctctag aatgaaaagt atgcgattta
     1261 ccttccgtaa caacggtagg tttattcaac tatgtgtccg atcaaaattt atctgatttc
     1321 aaaatagccg agagaattat ggtggttaaa aactcttaac tatttaactt ccacagttta
     1381 gttgacaaac ccacttaatt ctgataacga aaaacatatt cgaatgatta aacagaagta
     1441 aatacttatt taaataactt ttaattttca tgttcataaa tgatttgaaa ccaaagcaaa
     1501 tgcgttgcac ttttcctccg tcttccgaaa atcgttcaat tcactggtaa gtagtcattt
     1561 gatagtttga ggcaaattgt tgattgatga agggtaggag ctaaaaaaag ataccagttg
     1621 aagagagaaa aagaaaaaaa tagagggtgt tcttgaatga aaaaagttgg aaaattattt
     1681 ttcatttcct tttattccta ttaaaatcag tgatgtcaat catattaaca agactaaaaa
     1741 tgaaaataaa aaaaagattg ttcttagtat tgactcataa aaaataccac tactatactt
     1801 acattgtggt tatagccagt taggagagac atcgatgcaa aatacctttc aatcaaaatc
     1861 actttattat cagctggtag aaatattgaa acaacgaatc gaaaacagta tggtcgctca
     1921 tgacaagctg ccatcagaaa gagagttgac cagtttttat ggcgttagtc gcacgacggt
     1981 gcgactagca ttgcaagaac tggaaaaaat gggctacatt tatcgacagc atggaaaagg
     2041 aacctttgtt tcggaattaa ggacaaatgc gactgatcta gctggcgcat atagttttac
     2101 cgaacaaatg cgggcaatgg gcaaacatcc tgaaaccaag atattggcct tcaagaagat
     2161 tgaagcaact aaatatttag cgagtcatct gaatgttcaa ctaggtgagc ctttatttca
     2221 attagaccga ttgcgcttag ctgatgattt gccaatgatg atcgagaaat cctatttgcc
     2281 agtgaagcta tttatgtccc tttctcaaga aattctattt ctgaaacctt tatataattt
     2341 gttttcagag aatttcaatc aaatcgtacg gttggctgac gaggaatttt atgccagcat
     2401 tgtccagaaa gaagatagtg agttgctaaa tattccagaa ggatcaccag tgctccattt
     2461 agttcgctca acctataatc tcgagaacga agtgattgaa tttacattaa gtgtagcgcg
     2521 ggctgataaa tttcattata agatcaggca tctgcgttcc actaactgaa ttggaggaaa
     2581 gaaaatgttt atgttctcaa aagaagaact acgaaagcta ggagcagaaa atactacccg
     2641 agaaattcga caacaaccgg aactgtggca tgagacgttt gaccgttatc aagaaacagt
     2701 tgcagattta gatcgtttgt ttacggatgc gaaacaacat gctggagagc gaccaatccg
     2761 agtcattttt acaggggccg gaacctcgca atatgtggga gatacactaa ttccgtttct
     2821 tactagtcaa ggaaatacga accagtttat ttttcaaagt attggttcga ccgatatcgt
     2881 tgctacgcca aaagaatacc tgattcctga tgagacaacg atcttggtct catttgcccg
     2941 tagtggaaat agtccagaaa gtctagccgc agttaagatg gccaatcagc tggtcaacaa
     3001 gatctatcat atcgtgatca cctgtgcacc agacggatta ttggctacac aaatgcctac
     3061 aaaaaaagaa aatctagttt tactaatgcc aaacaaagcc aatgacgctg gttttgctat
     3121 gacaagcagt ttcagctgta tgacgctgac tgcgctactt atttttgatc aagcaagcaa
     3181 tcagcaaaaa gaaagatatg ttcatcaatt aagccgacta ggagaagaag tcatccaacg
     3241 agaatcagag atccaagggt atctggcatc agactttcat cgcatcattt acttaggttc
     3301 gggaagttta ggcggattga ctagagaagc gcaattaaaa gttctcgagt taactgctgg
     3361 aaaaatcgca accgtatttg atacatcttt aggattcaga catggtccca aatcttttgt
     3421 caatgagcaa acattggttt tcctgtttgt cagcaatgac tcatatacgc agaaatacga
     3481 tgtagacatg ctggaagaaa tcaaaaatga cggtattgcc caacgcgttg ttggaattgg
     3541 tcaaaagggt tcattgttta gtggtgattc ctttgaatta gttgcagatt cgttactgcc
     3601 ggatggctat cttgctttag cagatatcat ggtagcccaa acgatcgcat tactttgttc
     3661 ggtgaaggtt ggtaatacac cagatacacc atcgccaagt ggaacagtca atcgtgtggt
     3721 caaaggcgta acgatttatc catatgaaaa ataggaaaga gtgtgaagca tgttagaatg
     3781 gtcggaaaat aaaagacaag caatggaacg tctatcgacg ccagaaggca ttattaccgc
     3841 tttggcgatc gatcagcgag gcgcgctgaa gaaaatgatg tcggctttag ggatggaagc
     3901 gacaaaggaa aaaattgagc agtttaaaac actaatttcc caagaattga ctccttatgc
     3961 ctcagcaatt ttattggatc ctgaatacgg actgcctgct gcacagaagc gtgcagcagc
     4021 gagcggtctg ctgttggcat atgaaaaaac tggttatgat caaaccgtac ccggccgctt
     4081 gccggatctg ctgtcggact gttcagttct gcgattgaaa gagttaggtg cggatgcggt
     4141 gaaattttta ctgtattacg attatgaaga agcagaggaa atcaatcggc aaaagcaagt
     4201 ttttgttgaa cgaattggaa gcgaatgcat ggctgaagga ctgccatttt atttagagtt
     4261 attgtcatat gatgctaaaa atgtagatac gaaatcgctt tcctatgcca aagcaaaacc
     4321 gcgcaaagtg atcgaaatga tgaaagaatt ctcgaaaacc cagtataaag tagatgtctt
     4381 aaaggttgaa gtaccagtaa acatgtcatt tgttgaagga aatgcaacag gggagatcgc
     4441 ctatacacgt caagaagctg ccgcttattt taaagaacaa agcgatgcaa cagatttgcc
     4501 gtatatcttc ttaagtgctg gggtatcagc ggcattattc atggagacat tgcgttttgc
     4561 caaacatgct ggggcacgat tcaacggtgt actctgtggc agagcaactt ggaaagatgc
     4621 agtcgctcct tttgttgaaa aaggagaagc ggcaacttta gaatggctga cagaacaagg
     4681 gacacaaaac attcgtcaat tgaatgaagt gataagagaa actgccatcc catggtatga
     4741 gaaagtaagt gaaagcactt gttaatgttt ctaatatatt agtagtgata agagatatgt
     4801 gtgattataa tttatcatta ttgaaactgg gaggatattt tatatgaata aaagattgtt
     4861 agattattca gcttcagatt ttttgaaagc taagccgatg gaattaaagc aggcaatttt
     4921 ggcttctgaa ggtagaacaa ttatggcaga aaatgtgcca agtagctgtc cttacatggg
     4981 aaaatcagtg acaaatgcag aattggagag agctgctgga gctgatttaa ttttgtttaa
     5041 tgcactagat ctttttaatc ctcaaatttc aggtgtacct ttaactctaa aagagaatcc
     5101 aataatctgg attaaaaaag ctttaggaag agctattggt gtaaatttag aacctgtaga
     5161 caaagaagtt ttgatgagtg aaaatcgaac tgaaatttca agtggtagaa tcgtttctcc
     5221 tgagacttta aaaaaggcaa atgaattagg ctttaatttt atttgtttaa ctggaaatcc
     5281 aggaacagga gtatctaata gaactattga gaaagcaata acattatcca aatcaatttt
     5341 taatggatta attatcgctg gaaaaatgca tggtgctggt gttgatgaac caattatgaa
     5401 cttagatata gcaaaaagat ttattaaaac aggtgtagat attttattag ttcctgctcc
     5461 atacactgtt ccgtatttca tggaaagtga tttgcgagga atcgttgatt atataaaaga
     5521 ttttaataga aataaatcta ttgaggaaaa agttctagta ctaacggcta atggaacaag
     5581 ccaagactct tctgaccaag aaactattaa aaaaattgca ttagcatcaa aagcatgtgg
     5641 agctgatatt caacacatag gggattcttt aaatggtatt tgtcttccag aaaatatttt
     5701 tgctttgggt caagcaattc ggggatatcg tcatcaaatt attatgttag gaaaatctaa
     5761 ttatcgttaa ttaaggagga aatgaaagat gatcgacaaa gttcaaaaaa tagctgcaaa
     5821 aattagtaat caaagacatc tactagcttt aagagacagc atggctgcag ttatgccatt
     5881 aatcattatt ggttcctttt ttatgttatt agcaaatttc ccgatagaag gatttacaaa
     5941 atggttatct gaaattggag tacaatcctt tttgaacaaa gcatcagatt caacatttgg
     6001 tattattgga ttagctgtta cctactcttt gggacacaat ctagcaaaga cttatggtgt
     6061 agactcatta tcagcaggat tattatcttt gagtggatat gttttactta cacctttatt
     6121 ggatgcagat ggttctatag gatttccaac aaaatacttt ggtacctcgg gtctttttgt
     6181 tggtattatt gtagcacttg tatctacaga aattttccgg tggtttgtac ttaaaaatat
     6241 tacaattaaa atgccggcaa gcgttccacc aaatgtaagc cgagctttcg ttgctattat
     6301 tcctggcttt tttgtcgttc tactatggtt tattgttgtt gtaatttgtt ataaacttgg
     6361 aattgaaaat gttcatgctc ttattgcaga tacactcgca aaaccactat ctttactgac
     6421 gaaaacttta ccaggaatta tattggttat acttattcaa tgtttctttt ggatgtttgg
     6481 tattcatggt gcacaggtaa cggggccaat aattgaaccg ttattattgc aaaactctga
     6541 tgcaaataga attgcttatc aagctggaaa agaacttcct aacattataa cttatgaatt
     6601 cttatataac tttgtttttt ctggtggtgc aggttgttta tttgcacttg ccattttaac
     6661 atttttcttt tcaaagagtc aggaaaataa aactttaggt aagttatcaa tcgctccagt
     6721 aagttttcaa gtagcagagc cccttctatt tgggtttcca actatattaa atataaaaat
     6781 gttaattcca tttgtaactg caccagtagt aacaacatta attacttatt tttcaatgag
     6841 tatgggatta gttgcaaaac ctgtaggagc aacaatccca tggacaactc caccgataat
     6901 tgccggattt ttagcttctg gtggacgaat aagtggtgca gtgattcaag taataacaat
     6961 tgcaataaat gttttgatat actatccatt ctttaaatta gatgataatg ccaagctaaa
     7021 aagcgaaaaa aatgattaga actacctata tgtttctaac tgtagttaag tatgaaaaga
     7081 ctatttttaa atttagcatt tttgcgctat cggcgtagat gaagtatcac gataacgaaa
     7141 ttagtttctt tcatttaga
//
LOCUS       DAPBBR010000096         6643 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPBBR010000096 DAPBBR010000000
VERSION     DAPBBR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.101"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1..859)
                     /locus_tag="RD488_002600"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="RD488_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="RD488_002601"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="RD488_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDT7658618.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="RD488_002602"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="RD488_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="RD488_002603"
     CDS             complement(2603..3421)
                     /locus_tag="RD488_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7658619.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="RD488_002604"
     CDS             3582..4271
                     /locus_tag="RD488_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7658620.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="RD488_002605"
     CDS             4285..5787
                     /locus_tag="RD488_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7658621.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="RD488_002606"
     CDS             5800..6276
                     /locus_tag="RD488_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7658622.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         2172 a         1033 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttccttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAPBBR010000097         6051 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.102, whole genome shotgun sequence.
ACCESSION   DAPBBR010000097 DAPBBR010000000
VERSION     DAPBBR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.102"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..587)
                     /locus_tag="RD488_002607"
     CDS             complement(<1..587)
                     /locus_tag="RD488_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658623.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVF"
     gene            complement(735..1277)
                     /locus_tag="RD488_002608"
     CDS             complement(735..1277)
                     /locus_tag="RD488_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDT7658624.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1412..1801
                     /locus_tag="RD488_002609"
     CDS             1412..1801
                     /locus_tag="RD488_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658625.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1805..2569
                     /locus_tag="RD488_002610"
     CDS             1805..2569
                     /locus_tag="RD488_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7658626.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2698..3645
                     /locus_tag="RD488_002611"
     CDS             2698..3645
                     /locus_tag="RD488_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7658627.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3775..4515
                     /locus_tag="RD488_002612"
     CDS             3775..4515
                     /locus_tag="RD488_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658628.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4806..5474)
                     /locus_tag="RD488_002613"
     CDS             complement(4806..5474)
                     /locus_tag="RD488_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7658629.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            5608..5895
                     /locus_tag="RD488_002614"
     CDS             5608..5895
                     /locus_tag="RD488_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658630.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
BASE COUNT         2144 a          998 c         1160 g         1749 t
ORIGIN      
        1 ataaatacac ctagactgac gatgaagagc atatccaaca gatttcctgc gacttggatc
       61 gtcgaagggt tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa gctgtaaata
      121 aaacaggtga caggaactaa tcgaaagaag agcggacatt tcaattggct aaaaatgagt
      181 gaaaaaataa aataagtaaa aatggataaa atcacgacta aaccattcat gataaagaag
      241 aaaagcgtat tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa cgttttaaat
      301 gcaatcaata cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa aaaataggca
      361 ccgaaataaa cagaaaacag taagccgcaa agagaagaca aaatcaaaaa aaacggattt
      421 tcttcggctt ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc actagaaggc
      481 gcatgtgagg tcttaaggta tgaataacat agaaaaaata agatcgtcaa agttgcaaaa
      541 aaagagccta aatgtaaaaa attagtggtt ctacgttgaa tttccataat atctccaaat
      601 taaattgata agtatataaa gtataataac aaattgatga gtatatgtcg atgtttttta
      661 atcaaaataa taaataaaaa ctgtctaaca tttaaaattt aatttagata ttagacagtt
      721 tttaagtttg tgagttattt tccttgtcgt tttctcactt ttttagtcca gaaaccacct
      781 gaaatatatt ttggctcata agaaatgata aaagcacgct cttcgatttc tttgatcagg
      841 cgatacagtt cacgttcgct ttttctagga gaaagtattt cgagaactag ccgctcacct
      901 tccagcccca ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag tatacccggc
      961 aaacttttat cttctgcgct atttgctggc aaaatcgttg tgaccatgat gtatcctaat
     1021 gccaatttgt cttcaatcaa aattccgaca ctgataccta ctgcgtaacc taacgcatag
     1081 acaaataaat tcagtggatt atctaaacga tctaaaacaa gggataagcc gacgatataa
     1141 atcgtgatct cgaccatact gacaagtgga gcaatcagtc gatagccttt cattgtcaac
     1201 atgaaacgta acgtgttcag agtgatataa gcaaaattaa tgaggaagat catccccaac
     1261 atttttggat caatcatttg taaaactcct ttcatttata taacaacaat atcaaaaaaa
     1321 atcgtaagtg aagaaaaatt gaaactttat acatacaaaa aaatgataaa atgattataa
     1381 tagaattata aagataggtt aggtgattaa aatgaaaacg gtcaatcgtg tgttttgtgc
     1441 cagccacgtg ctaagtctcc ttctcagtat atacttaggt gtctattcga ttcaacagcc
     1501 aattgaggta gagaacattg tttttcagat gtcgctgaca gatggtttaa ttttaagcgt
     1561 ttttttcttt ttgatactgt ttattggtaa tattttcggt agcgttgcca gttttttgaa
     1621 tttttctatt tatccactcc tttcgctagc attaggagtg gtgggacttt gttctctgtg
     1681 cttatttccc gagccattca gtcctgcatt tatattattt ggtacactga acctgttcca
     1741 gacaactgtt ggagcatggt tgctatggcg atcaggaaat ttaatgaaaa taggtgagta
     1801 acaattgaat ccaattatat tgaaacgttc tgtccatcat attccagtgt tagaagttgt
     1861 tctgaaagaa ttaagagagg aacgtattcc cgttgtcatc tattatcacg gatggcagac
     1921 aagtaaggag ttagttttga cgcaaggaag aaaaattgcg cagcagggca ttcgtgtgat
     1981 cctgccagat gcgatgaatc atggggagcg caaacagccg gtttcttcta ttccatccta
     2041 tacattttgg gatagtatct acggaaatct gtttgaattt gacacactta tcaagcattt
     2101 agaaaaaaga ggtcttctac atgatcagct tgcagttggc ggggtttcga tggggggaat
     2161 gacaacatgc gccttgttgg ctaaacatcc tcatatagta gcgggcgtgt gtttgatggg
     2221 ttcccctgca cctttggaat atggaaaaga aatcgtaagg cgcgcatcgg aatataatta
     2281 tgtcgtacca aaagactatt ttgatttgat ttcatgggtt aagagctatg atttgtcatt
     2341 gcagccggaa aagttagctg gacgtcctct gttcttttgg catggacaag ctgacgaaaa
     2401 aatcccttat atacaaacgg aacgatttgt agaaaaaaat cggcataagt cttacggaaa
     2461 agaaattgtt tttcgttcct caaaaacaca gcgacatatg gtacaaatac cactaatgga
     2521 agaagcttcc acttttttag caaaaaattt gataaaaaag tataaataat tgaaacggaa
     2581 aatcactcat gacgatagag gattttccgt tttttatttt gggctataat aaactctgtt
     2641 aggaaaattt ggtataattg atagtaagaa tgacaacatg ttagaaagga agagagcatg
     2701 cccactttag cagatgttgc aaaacgtgcc aatgtttcaa aaatgacggt ctctcgagtc
     2761 atcaatcatc cggaacaggt gactgacgaa ttgaaagagt tagttttctc agcaatggct
     2821 gaactggatt accgtccaaa tattgctgca aaagcacttg tcacgaatcg gtcgcagatc
     2881 atcaaattat ttatactgga agaaatcgac acaactgagc cctattacat gaatttgctg
     2941 atgggaatcg ctaaacggat cggtaaagcg cattattctc tccaattagt tacaaatgat
     3001 gccttcgacg tcggttcttg tgatggatac atcatcacag gtgtcagaaa aaaagacttc
     3061 gattggatcg accgtttgga aaaaccagtt gtcttgtttg gggaaaattc tgaaggatat
     3121 gattatgtag acagcgataa tgaatatggt acagcaaaag caacgcaata tgccttagaa
     3181 agagattatc aaacgattat ttatatcggt atcgaagtgg acgagccttt tgaaatttca
     3241 agggaaactg gttatttatc tgtgatgaag gaagttgatc ttcctagtaa aatcttgcgg
     3301 tttccaaatc attcgacaga agtagaaaga tatatgacag aaaactgggc agattttaca
     3361 gataaaactt gttttgtatg tagttcagat cggctagcac taggagcagt aagagggatt
     3421 ataaatgctg gaggacactt gcccgaagaa tttggtgtga ttggatttga tggggtattt
     3481 ttagaccaaa tcagttcacc taaattgaca acgatcaagc aagatattat acgtatgggt
     3541 gaagtatgtg gagaaatgtt gttaaaaaaa atagaagaaa aaggggcgag tcaaggttat
     3601 cgtcgttttt ttcctgaact agttatcaga gagacaacga attaagtctt attactatat
     3661 atatatttat gaaattcatc gctattttct taaaataatc agcgcattgc tactgaaaac
     3721 aatgaatctg tgctattatt gagaaaagtt ccatttttga gaaggatggt ttgaatgaaa
     3781 gaaatcagac gaaaacattt ccgttttcct gcgtacgatg atgagttagg cgtaaaatta
     3841 accaacgaca agaagcgagt attatttgac ggacaagaag atcttttgac tgaacagaat
     3901 cagtccccgt ttgaacagat gaaagaattt catttcacga acacgaacac cgagaaaatc
     3961 cgtcgcaagc gtcgtgcaac aaatggattg aagtcagctc cgcgtaagga aaatttggaa
     4021 aagcataaag gaaaattacc ggattatacc ggccattacc aatcagaaat cacatcgaca
     4081 ggacgaaaaa aactttttgg tgattcctct cgttctgtca gacaaagtga aacaaggaca
     4141 gagtccaagc atactacacg aaacgcatct gttgacacga aggtgcggga gcgttcttat
     4201 tttgttccta aatatgtacc cgcatcgatt atcccagacc ctagagaaag caaaatttct
     4261 gaggatcatt taatcgaatc gatgaaaaaa acggatgact cttatctgtt gttcgataca
     4321 gaaccgacgc cgtatcaaga aaaaagaaat ggtgagccgt ctgtacgaac attcaatcga
     4381 acaaaaacgt tagaggaaac aaagcagtca gaagaaaaaa aatcgaaaaa aagccatggt
     4441 atcttagaac gctcattaca aggattgatc gatgatcaag gaaactcttt gggagaaaat
     4501 agctatttta aataagtgat atacaaattt atattcggct acagttggaa aggaaacgct
     4561 gcggcgtttc cttattttat actctatccg aaagtttata tcgtatcctc aaattttttt
     4621 gagtttaagc gaattttttc tcccaataag taagaaaata atggcaaaat aaaaaaacaa
     4681 actattttcg cagatcgttt gcaaaaatag tttatttttt tataaagaag attttactga
     4741 ataatatcat tttagtttac ataatgatat ttctgtaaat taaataaagt agtgaaaaat
     4801 aagaatcagt gctctaactg ttcaagagga tcaagtggtt caaatgtttc tgtagtctgt
     4861 tttgcttcca attggggcaa aacagatcca atttccagat acttcacttt attcaatgta
     4921 taagatagaa tagaacagct aagtaatgta tacagaaaat gtgtgagatc caaataaagc
     4981 aaggagacaa ctaaaatacc aaaagtaatc aagaaaagac ttttgccaat cttaatatga
     5041 aaatattttt caatggcttg ataaatgata tctgttccgc ctgtgcttcc gccgaatcga
     5101 aagacgagac cgcaaccaat gccagaaaga atacctgtca tcaaactatt gatcagtaga
     5161 ctatctacag caaaatgtat atgaaggctc tcccataaat gtaaaaagaa aactagcgca
     5221 aatgttccga cgatcgtccg gagaaaagcg tgttttccaa aaagaaacaa tgagataagc
     5281 aataaaggta aattaaaaag cagtgaagtg acagaaggag cgaatccaaa aagattatgc
     5341 aaaagcaaag caataccagt aaccccacca tctgccagct tagatggaat attgattcct
     5401 gtcacagcta atccgtagat tcctgcgcct aaaatgattc cgcacaattc tgtaaataaa
     5461 tttaattttt tcatttctag cctcttttct tttgaaaatt ttcagcaact tctttattat
     5521 actgacttat actcttactt caagaggaaa atgaaaaaaa attatttttg gctgtttctt
     5581 tttatttatc aaataaggag tggaaaaatg cgagcagcag acttattgac aattcttaca
     5641 aaatcaccca aaaaaacaga gtatcaagga gtttttttgg ctcaagaaca aaaactggtg
     5701 cctgtgacaa tggtccagat aaataaagca aatcaattta tctttttatt tgaacacggc
     5761 aaagcaccac ttgctatgaa agacatcttt ctttttttga tgaagaaccg tgagaaagct
     5821 gtttattatc agtcaaaaga agaactcatt cctctttatg gagtgaaaga gatagaaaat
     5881 aaagtggtga tataagtaaa aataagaaaa caagacgttt atgatgtcaa aacaaccatt
     5941 ttttacattt ttggcaaaaa agtgtcatga tacagtataa tattcgttga acaggccaat
     6001 aaaggtgttc tcccccacga gatttctact ttattggctg tttcttttta t
//
LOCUS       DAPBBR010000098         6044 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPBBR010000098 DAPBBR010000000
VERSION     DAPBBR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.103"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(29..1501)
                     /locus_tag="RD488_002615"
     CDS             complement(29..1501)
                     /locus_tag="RD488_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDT7658631.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWINDPNGFIY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVMEGKVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMTAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQEKIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPHHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            complement(1515..2363)
                     /locus_tag="RD488_002616"
     CDS             complement(1515..2363)
                     /locus_tag="RD488_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7658632.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LTSFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            complement(2360..3226)
                     /locus_tag="RD488_002617"
     CDS             complement(2360..3226)
                     /locus_tag="RD488_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7658633.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQLGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            complement(3269..4582)
                     /locus_tag="RD488_002618"
     CDS             complement(3269..4582)
                     /locus_tag="RD488_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDT7658634.1"
                     /translation="MKRRMLAIAAILALTAGGLAGCGSKEKSSGSSDSGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMESGDEMLTYAY
                     TPFVWSNGGDVVNADGTKAEDYFNDKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMLLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDGSA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQISGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQVIDTSLK"
     gene            complement(4724..5695)
                     /locus_tag="RD488_002619"
     CDS             complement(4724..5695)
                     /locus_tag="RD488_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7658635.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGFSPYPNETNNRKAGFYNICEKNKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            complement(5821..6044)
                     /locus_tag="RD488_002620"
                     /pseudo
     CDS             complement(5821..6044)
                     /locus_tag="RD488_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         1827 a         1309 c         1024 g         1884 t
ORIGIN      
        1 accataaatc atcactgagc tctcccttct atagattaat taagccgctt tccaatgaaa
       61 aggttacttc actgtctgcc agcaaaagaa aatcctgtcc tttttctgtc tcataaaaag
      121 ttgtactcat agtcagacga tcatttagaa aaagctcaat agctgaagta tcacggaaaa
      181 tttcgatggt tagacaatta ttttccaaag gaatcgtcac actgcgcttt ttcaacactt
      241 ccttttcagc tcctgataaa tcatacggca tgtgttccct ggaagcagta aagcactccc
      301 gttcaacatc atagttaagc agtaatgtat ggtggggtcc cttcgcatag tgaagttcta
      361 gtttcgttgc ctgttttaaa ttgatttcca agcgtaaata gtgctggtca tatactaagt
      421 ccttcagtaa gaatcgattc tcttcagtct tcgcccattc aatcttttcc tgcggatcaa
      481 ttacttgata aattgatgaa actggccgtt gcaacaattg attatcagcc accctcagct
      541 ctctaggcaa ggtcatggaa cctgaccaac catggcccag atcattcgta ggtattttac
      601 gctgccacat ttgcatccaa gcagtcatta ttctttggcc tgcttcgttt tcacaggtct
      661 ggggggcata aaaatctaaa ccgccatcga tttcatgaaa attctctact agaaatttgc
      721 ctgtttgcca atcgacagta ccaatgaaag caacagttga gttcgtattt tggtaagcat
      781 tgccttgtgg agtcatttga ataggagaaa gaatcaagac ttctttgcca tctagttcaa
      841 acaagtctgg gcattcccat acaatgcctt gttctggagt tccctccagc aatacggaat
      901 aaaactccca agttagtaaa tctttggaat ggaacatcac aatttgtcca cgagcatctg
      961 cagttttagt agcgactaca gtaaaatagt cttcttttcg ctgaaacact ttgggatcgc
     1021 ggaaatcttc ggtcgttgca acagaagcta agtgatcttc tgcgatgatt ggatttccgg
     1081 catatttttc aaagtgaatg ccatcttctg aaactgccaa acactgaact tgtcgaactt
     1141 tcccttccat aacattgtgt cctgtataaa tcaaatacag cttgccatcc ttttctatag
     1201 cactgccgga aaaacagcct tccttgtcat agctttcacc tggtgccagt gctactggca
     1261 aatgctccca gtgaattaga tccttgcttt tagcatggcc ccaatgcatt ggtccccaga
     1321 tgctgtcgta aggataatat tgataaaaca agtgatactc ctcttgataa taaataaaac
     1381 catttggatc attgatccag ccaatcggag ccatcaaatg aaatttattc cggtattctt
     1441 gattgactgt ttgagcattt ttctcaataa actcattggc ctttaaaagt ttttgcaaca
     1501 ttcactattc actcctattt tatacccgtt ccagaaccgc caagtccctg cagaatatat
     1561 ttttgtgcaa cgatataaac aataatcagt ggaatcgttg caatggttaa aacagccatc
     1621 acttgattga tataaactgg ctgtgtagta ttgatcgtag taattgccac ttgcattgaa
     1681 aatttgctgc tgtcagttaa gaccattaac ggccaaatat aatcattcca gctggagata
     1741 aaggataaga cacctactgt ggctatggct ggtttagaca ttggcagcat gatgtgaaag
     1801 aaaattttaa caatatttgc accatctaat ttcgctgatt caatgatttc ttctggaatc
     1861 gcgataaaga aatttctaaa caaatagata ttaaacgcgc tggccatcgc tggtaaaatc
     1921 actgccaagc gagtattcac taagcctagt gaattaacga tggtaaattg cggaattaaa
     1981 accgtctcca tcgggacaat cagcagagct aacaaagctc caaagataat tttcttgcct
     2041 gaaaaattaa ccttcgcaaa ggcaaaaccc gccaaagagt ttacaatgat tgacccacag
     2101 gcaaaggtta aaccataaaa aatactgttt aataaataag ttcccacact gaaccgggaa
     2161 ataacttctt gataagtttt aaaccaatta gctggattca aactaggtaa aaaagctttg
     2221 aaggaagtta aattttgata gacatctgct tcaggcttca tagaggaaac taccatccac
     2281 agcattggga aaatgaataa tgccgctaaa aggaacagca aacaatattc tacgatcatt
     2341 agcggtccaa atttcttagt catgctggat catcctcctt taccaatttt ctttgagcaa
     2401 ttgtaattaa accaatcatg gtggtaaaga ttaacgcaat ggagctggag tagcctacca
     2461 tacggtctgt aaatccagtt tggtaaatgt aataaaccat tgtcatagta gaattcattg
     2521 gtccaccttg agtcattacc attggctgaa tgattagttt aaaggccgaa atcaatgtgg
     2581 taagtaaaat aaaaatcgcc gtgggcttta ataatggcat ggtgatatag cgaaattgct
     2641 gaaacttaga aaaaccatca atttcggctg cctcataaac gtcttgcgga atgttttgca
     2701 ttccccctaa aaacagcagc atctgatatc ctgcaccttg ccatgccgat acgaaaacaa
     2761 gcgtatacat tgcttgtttg ggactagtca aaaaaggctg cgaagcaatt ccaatctttg
     2821 caaatagcgt attaaccaga ccttcattag gatttaacaa gtacaaccat aaaatcgaaa
     2881 taacgactaa ggacatcacg actggcgcaa aaaaggctac tttaaaaaag atatttcctt
     2941 tacgattttt gttgataata agtgccattc ctaaagctgc ccctaattgg accggaataa
     3001 tccaaacaac aaatttagcc gtgttccaaa tactttttac aaaaattgga tcagcgaaca
     3061 gtcgcttaaa attttctaag ccgataaatt gtctagcatc tggcgttaac aaataataat
     3121 cagtaaaggc ataataaatt accatgatta cgggtatgat cagaaaaatc gtcagcagca
     3181 gcaaagctgg cgctagaaat ccgtaaccta tcaaattgtc tttcattgtc ggttttttta
     3241 acacttgatt ggcccccttt agaaacttct attttagtga agtatcaatt acctgttgca
     3301 tttcagcagc gcgactatct gctacttttt gtacatctgg gttttcctcg aagtagctaa
     3361 tatcttgaac tgcttgttgg aatgctctag atacttgcgg ataagctaca accactgggc
     3421 gggcatgtcc agaaatttgg ttttgcttaa ttaatacctg cattccttcc gacacttcat
     3481 ctttaattaa atcaactgtt gaatttctga taggtagaac actgttccct aaactcataa
     3541 tacgactaga ttctgtactg gttgcaaact taataaaggc cgcagaacca tcctttttct
     3601 ctgttttctc agtcattgct aactgccagc tgccggttgg tgaaactaac tccccagttg
     3661 catctgaaac ggggtaaggc aaaataccat aatcaatctc ttgatagttt tcctctaaat
     3721 ctgccattgt ccaagaaccg ctcagcagca tggcatattt gccagtttca aatccttttt
     3781 caataggact gattgtggtg taaccttttt caaccaattc ttgaataaat tccaacgctt
     3841 caacggattt tttatcgtta aaatagtctt cggctttggt tccatcagca ttaacgacat
     3901 cgccgccatt cgaccataca aatggtgtat atgcgtaggt cagcatttcg tctcccgact
     3961 ccatttgcat atcaattgca ggcgttttgt atttatcagt cagcttttgg caaattgctt
     4021 gaaattccgt ccaagtccaa ggatcttcta acgtcggcaa ttgatcttct gtaattccag
     4081 catctttgaa caacgactta ttgtaataga cacccacact ggactctgag aaaccaaacg
     4141 catacatttt gccatcgtag gttccttgct gaataatgct gtctaataca tcatccatgt
     4201 ccgcatcttt caaataatca tctaatggag caatgactcc tgaatgagca taagctgcag
     4261 tattcggtcc atctaacgta ataacatcag gaagggtatt ggttgtaatt gcagcattta
     4321 ctttatcctc atatccaccg ccgcttccgc tacgaggaat atactcagta acagctttat
     4381 attcaccctc gtattcatca ttaaaattgt tcacaatctc tgcccaagct tttccttcag
     4441 gcgtttcatc agaaaactga acccaaatct taatttctcc tgaatcactg ctgcctgaac
     4501 ttttctcctt actgccacat cctgcaagtc ctccagctgt taatgctaaa attgctgcaa
     4561 ttgctaacat tctccttttc atcgatgttc ctcctatttt ttgaaacgtt tccgttttat
     4621 tctccaatta attggtaacg tttccaatta attggtttta agatatcatt gaaaccactt
     4681 tctgtcaacc tatctcaaaa aaaaatcgtt ataaaccggt tttttactct ttagtcgttt
     4741 ctccagcgtg aaagaaaacc ggtactacca cacgcttagg cggttcttca tttaaaatca
     4801 tcgccatgag tgtttctact gaaaccttgg ccatttcctc tatcggctgt acaatcgtcg
     4861 atagtaaata gtctttttgc aacgatagct tgactccatc aaaaccaata atttgaaaat
     4921 ccttaggtgc ttccttccct agtttttttt gggcttttat cacatccaaa gccatgaaat
     4981 cattgatggt aaaaatgcta tcaatttcag gattatccga aaaaaaagcg agcaattgtt
     5041 cctccaaatt gctaattggt tcaggcatat ccaatacctt cacagctatt ttatttttct
     5101 cacaaatatt gtaaaaacca gctttacgat tgtttgtttc gttagggtaa ggtgaaaaac
     5161 ccccaacata gcacaagttt ttacagttac gagtaagtag ttcttgagcg gcaatttgcc
     5221 cacctaaata attatctgcc gttacataag aaacctgttc cgaaaaatgg cggtctatac
     5281 tgacaaatgg taaatttgat gatacatatt tatcaatgtc tgaataggta atacctataa
     5341 ttccgtctac tttactctgc ttgaccattt ggatatattc tttttctttt tccgcactgc
     5401 cgttcgcatt acacaaaaaa agcttataat ttttttggct gagagcttcc tctacatagt
     5461 aggcaaactc ggaaaagaag ggatgccaaa tcgtaggtaa aataagagct attgtattgc
     5521 tgctattcgt tttcatacct ctggcatatt catcaggctc ataattaagc tcactaattg
     5581 cagccattac tttttctttg gtaacctctt tcacctttac tccatttatt actctagata
     5641 ccgtacccac accaactcct gctaacgcag caacatcctt catagtagtt ttcacttcac
     5701 gaacaactcc tctcaaaaga atttcaggta ttattatacc aaaagaagaa aacgattcca
     5761 aattagcagg aatattttta ttttaaaata gatattagac gtgaagcttt tcgtaaaaaa
     5821 attttcgtat tcagatttac cggattgact ctgtcgccaa tataggccgg catactttgt
     5881 caattttatt tcatcagaaa aacgttcaat tggaccaatt tcagcgagta ttccagcagc
     5941 ctaaacagga ccaatacctg ggatactggt taaacattga tactccggta gcaccacgac
     6001 taagtcgtca atggctttat ctaagtcttt aattaacccg tggt
//
LOCUS       DAPBBR010000099         5945 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPBBR010000099 DAPBBR010000000
VERSION     DAPBBR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.104"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..450)
                     /locus_tag="RD488_002621"
     CDS             complement(<1..450)
                     /locus_tag="RD488_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7658636.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="RD488_002622"
     CDS             674..1465
                     /locus_tag="RD488_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7658637.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="RD488_002623"
     CDS             1431..2384
                     /locus_tag="RD488_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDT7658638.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="RD488_002624"
     CDS             complement(2782..3756)
                     /locus_tag="RD488_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7658639.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="RD488_002625"
     CDS             3871..4305
                     /locus_tag="RD488_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7658640.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5452)
                     /locus_tag="RD488_002626"
     CDS             complement(4430..5452)
                     /locus_tag="RD488_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDT7658641.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5844..>5945
                     /locus_tag="RD488_002627"
     CDS             5844..>5945
                     /locus_tag="RD488_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HDT7658642.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIR"
BASE COUNT         1869 a         1121 c         1019 g         1936 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttatta ttctactaag ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact tttatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc gtctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taaga
//
LOCUS       DAPBBR010000100         5898 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPBBR010000100 DAPBBR010000000
VERSION     DAPBBR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.105"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(976..1149)
                     /locus_tag="RD488_002628"
     CDS             complement(976..1149)
                     /locus_tag="RD488_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658643.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1152..1550)
                     /locus_tag="RD488_002629"
     CDS             complement(1152..1550)
                     /locus_tag="RD488_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658644.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1766..2821
                     /locus_tag="RD488_002630"
     CDS             1766..2821
                     /locus_tag="RD488_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HDT7658645.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2841..3194
                     /locus_tag="RD488_002631"
     CDS             2841..3194
                     /locus_tag="RD488_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658646.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3376..3672)
                     /locus_tag="RD488_002632"
     CDS             complement(3376..3672)
                     /locus_tag="RD488_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658647.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3676..4494)
                     /locus_tag="RD488_002633"
     CDS             complement(3676..4494)
                     /locus_tag="RD488_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7658648.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4720..4941
                     /locus_tag="RD488_002634"
     CDS             4720..4941
                     /locus_tag="RD488_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HDT7658649.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4943..5209
                     /locus_tag="RD488_002635"
     CDS             4943..5209
                     /locus_tag="RD488_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7658650.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5322..5861
                     /locus_tag="RD488_002636"
     CDS             5322..5861
                     /locus_tag="RD488_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658651.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
BASE COUNT         2065 a          982 c          874 g         1977 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttt cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaatcaa aatttaaatg ttttaatatt acaaataaaa tcatgttatt
      541 gtaaaatggt ataaaaaagc taaatattct atttttgtta ttttattagc aggaaaattt
      601 aaatagtttt acaagaatcc gtagaaatat attggttttg ccttcagatt aatactggat
      661 catattaatc tgaatataat atatgaacta ataaatagct taacctcgct attttgtttt
      721 ttctgatcac tatctataca gcattagtaa atagaatttt aaaaataaaa aaattaagac
      781 aaaaaagtat caacataaac atatacatat acacgtttat gttgattcac ttaatttgtc
      841 ctttaaaaag cacttatttt aatataatgt tattttataa tcttattaca agctgattgt
      901 taggcgttgt cctttcatta catttattaa cggttatttt attgtttaat ttattaatta
      961 tttttgatct aaaacttagc ttaacaaata aataattaac caaccgccag ataaaaatgc
     1021 gatcattgct aatacataag caaagataaa aatatgttcg atcagcttaa accctgatgc
     1081 gattaagcag accaagtaaa atagaaattc tcttacagat aatggtaatt ttctaactag
     1141 catactcata attaacaccc caaagtaata ttgtattttg aacattttac atccaataca
     1201 gcatcaatca accattgcca atcaaaaata caaggcttca ttgaagtatg tttttcagat
     1261 gaaaagatat aatataattt cttcggaata atattttcag ttgttgggat caagctaaat
     1321 ctaataccgt ctaactcata gctaccagct ttctctccat taaaaatttc cttagcactt
     1381 tcttctaaag aatcaaaata tttttcgaca gcaatctttg aagcttttac tattgaagca
     1441 tttccctttt cgataaaatc tgcttttgtt ttaccgacaa taagtaattc ttgatcagta
     1501 aaatcttcta aaataatggt agtgtaattc ttatttcttc tcaatcgcat caggatcact
     1561 ccttaatata atttatgttt ttataatatc ataataagat aaatttgcaa gcatttattt
     1621 acaccttttt atttacactt tattataatt aattagactt ttatgattgc atttttttct
     1681 tataaacagt tgcaactaat agtaaatagg tgtaaactat tttcgtaccg aaataccata
     1741 aacacaaaca gaaagaggtc ataccatgaa agaaccatta ttgttttccg ttgacttagg
     1801 gaataaatca gtaaaagaaa tgagtacaca cgtttctcca ctctcacttc cctctcgtat
     1861 tttgaacaaa aatatcatta attcaggacg tttttctaat ataggttcct cattaaaacg
     1921 atcactaaac gtttctgaat atagcctagt aaacactact gaaagctatt actttgggaa
     1981 ggatatacac gagctaggaa aagatgacta cgtgatagaa tcactaggtt ttgggatcag
     2041 cagatacaag caggaaacct accaaaatat cctatctttc tctttagcta acctagcacg
     2101 tttagaagat caatctgatg acgttttaac cgctaatcta gttttaggtc tgccttcatc
     2161 cgactatacc gaaacaatcg tcaaatacgt gatgcaacaa gccacacgac aacattcagt
     2221 tgaagttgac ggtaaagctt ataatataaa cgtagatacc gtttgggtac tgccacagcc
     2281 gattggaaca ctatataacc tcctacttgc tgatgatggt agtgtacaag atgaaacatt
     2341 gatcagtcag aagatcggtt ttgttgatat tggtggtggc acgaaacttt ttgatgttgt
     2401 ccaaaatttt gaaattgacg aaaacaaccg tgaacaaaag gataccggta tttttacttt
     2461 atataatcgt atcgtaaata tgcttgacct tccgatcagt cctaatgctt tccaacttga
     2521 aaagattatc cgagaaggca aagaaaaagg cgtatatcta tttaaaccaa gcggaaatga
     2581 aagttttgat atttcagaag tagttgaaag agaaataaaa acatacacca atatggttgt
     2641 tgcagaagtt ttagctacat tcaaaaactt cacaacctta gataaagttg tctttactgg
     2701 tggtggggct tctattatcg acaaacaact tgtaaaagat aaaattccgc ataccttgtt
     2761 tgttgaagac agtgaatttt ctaatgtaaa aggcttttac aagtttggtt taactcaata
     2821 aaacagcgaa ggagatcaac atgaataagg gaaaatcaga gcgttatgta gttataatca
     2881 atagagaaaa ggttagcgag ttacctttag cagagtttct tgaatctgaa tatgaaacac
     2941 taggcgttaa atactctcag acgatcaaaa aagctttgaa tctatatcgg cgtgtaaaga
     3001 acaatgaagt tacaattatt gaagcaggca acgatagaaa cgatagcaaa gtagctgaag
     3061 taaagaataa accaactgat cataacccta ttcaacaagc gcatccttca acggttacat
     3121 ccgatcattc agcaaagaaa gaaaagccaa tgctaaaagg gttcaatgca ccaagtaaca
     3181 aagacttact ttaaaaataa aaaggcgagg ttacaatacc tagccttttt attatgtaca
     3241 aatacaaaca taaacatata cgtatacatg tatataaaca tgtatacgta tatatccata
     3301 aacacgtata cgaaatttag ttaagctata cctaaccgct tattccaata aaaaaagtga
     3361 tcagctttaa actgatcact caccaaaaac ttcatcatac aagttatcta tcatttcacc
     3421 aagtaaagct gaatctgatc gaattcctaa cttttcgctg attttagata gtttctttct
     3481 ttgtgatggt tgaagcgtga attgataatt tttcttcttt tcagaactat cactttttag
     3541 tttagctacc aaagaacttg ttgtttcttt aggtgtttgt ttaggttctt caactgcttc
     3601 aaccacttca ggaacttctt ctacttcagc ttcagcgaat tttttaaatc tattttcttt
     3661 cacttcaatc actccttatt cttgtgccgt atcaattatt ttgttgtata gcgtaaacgt
     3721 gctttcaaag aaatccttat tcttacgata gatattctta tccttagcga actcagcaat
     3781 attcttacct tctaagctag ttgcattaag caattccttc tcttgtacat atccaagata
     3841 attagataac gttggtacca attctaggaa ctcacgactt gaattagtat tatgtttgat
     3901 cctgctaccg atcgtagcgt atttagtttc catcagtgtt tcaccagtct taatatcaat
     3961 caactgtttt gctagtgcat caatatcttt accaagctta agcaaagctt caaaaccatc
     4021 tttagatgga tcagaaatgc ctacgacaag atcagataca gcccaagcat tttgagctag
     4081 tagacctgca tcattatgag tatcaatcag aattagatca tacttctctt taagctgttc
     4141 atagttaaca acgatccatc taaacagtag ggttctgttg ttaggcatat cacgcatttg
     4201 catctcaact tgttttaaat cttcacctgc tactaaaata tccatgttct catttatagc
     4261 taaaggttca gctgatccat gaagatataa atgattgatt gtattctctc ttttcgcttt
     4321 actgaaagca tcaggaaatc gttttgatag gttttgcgac ttatcttcat caatatacag
     4381 caccttcata cctaaatttt cgacagcata tccacctaga ttgtagattg ttgttgtttt
     4441 acctgttcca cctttttcaa tgtttccagt aatgattgac aacttctttt ccatgattaa
     4501 acctccctta ttaatctttt gtaactccat tatacactat aaacacgttt atgtatatat
     4561 ttatatacat aaacgtgttt atatttatat ttgcttttat attctacaac ataaacatat
     4621 atatgtatat gtttatgttt atgtatatat tcaaatatat aactattgca tttgtcatac
     4681 aatcgtagta caatgtaatt gaaaaggagt tgataaacta tgccagtaat aagtattcgt
     4741 gtatctaaag aagaaaaaga ttttcttgaa aaagttgctg aattcaacgg agataacatt
     4801 tctgaattta tgcgtagtaa ttccctgcaa acagcagaaa cgttagtaga ctttgccacc
     4861 tacaagcaac taatgaaaga gcatgaggaa aacgatcaaa gtatttccca cgaagatatg
     4921 ctaaaagagt taggcttata agatgactta ccaagtaaga tatgaacgtg aagctcaaaa
     4981 agcgctaaaa aaaatggata agtttcaggc aaaggttatc ctaaactgga tcgagaaaaa
     5041 tcttgtaggc actgatgatc caagaaagca tggtaaaggt ctaacagcta ataaatcagg
     5101 ctactggcga tatagggtag gtgcataccg tataatagct gatattagcg agcatgaagt
     5161 gacaattctt atattgtcta ttggtcacag aagtgaagtt tataagtaac agacaagctg
     5221 ataaggcttg tctgtttttt tgttaaccca acaaaatcac tgtttacgat cccactttac
     5281 ctaaaaaaga acaatatcct cttgatatta tacacaccag tgtgtataat ataagtgtaa
     5341 acaagctaat taactttcaa aaggagcgat tttttatggg atggtatggt gattattcat
     5401 cagcaaatga agtgatcgaa gaaaagaaag ggtacgccaa aaatggtttg gaaatcgtag
     5461 gtaccaaagt aacgaagacc tatggaatta tccttttcaa agatgcagaa ggaacctacg
     5521 atattgacag cttcatcttt cgagatgaaa tgtacaaacc aatctacttc ttaaatgaca
     5581 gtcctgctta ctttaagaaa attccgaaaa aatggttgaa attctttgtc ggtgatcaag
     5641 aaaaaatggt taagctacaa ctagatagaa ttaaagaaga aagcaataaa ccaaaacttg
     5701 atgacttatt agttgcaggt aaaacttact caatctggga tggatcgtat gtcgctgtct
     5761 atcagtataa actcaaacgt agctttattt ttcgactaca agatggatca ctcactcggt
     5821 tcactcgact atcagcagga gatgttaagg aagtaaccta aaacttaaat acataaacat
     5881 aaacgtgtat acgtttat
//
LOCUS       DAPBBR010000101         5743 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPBBR010000101 DAPBBR010000000
VERSION     DAPBBR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.107"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            191..916
                     /locus_tag="RD488_002637"
     CDS             191..916
                     /locus_tag="RD488_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658652.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            906..1415
                     /locus_tag="RD488_002638"
     CDS             906..1415
                     /locus_tag="RD488_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658653.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1485..2933)
                     /locus_tag="RD488_002639"
     CDS             complement(1485..2933)
                     /locus_tag="RD488_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7658654.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2933..3649)
                     /locus_tag="RD488_002640"
     CDS             complement(2933..3649)
                     /locus_tag="RD488_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7658655.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3630..3980)
                     /locus_tag="RD488_002641"
     CDS             complement(3630..3980)
                     /locus_tag="RD488_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7658656.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4124..4897
                     /locus_tag="RD488_002642"
     CDS             4124..4897
                     /locus_tag="RD488_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7658657.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5068..5434
                     /gene="ssrA"
                     /locus_tag="RD488_002643"
     tmRNA           5068..5434
                     /gene="ssrA"
                     /locus_tag="RD488_002643"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1666 a         1125 c          996 g         1956 t
ORIGIN      
        1 tattgtcgct gctcctcttt tcgaataaac agtgttcaaa agcttgcatc tacggtaata
       61 gaatagggca gcttcttcac aacctcttgc tttttacaaa atattttctg gttttaattc
      121 gtgatttcac taaaggaatt tcatacttta ttcatattca ttttctatac tttttataga
      181 ggtgaaaagt atgaaaataa tccgctatgc tactgctcga ttaatttatt acaaaaagca
      241 gacaatactc tattgtttat tttcaagctt ttctgctttt ttattgatag catgcctgac
      301 tctttaccat tcgcaatcgg ctttagccaa tcaagtccaa gatcggcttt catttattgg
      361 cgcttctgca tctacagagc ttcttccggc tttagaatta gctagccgat tttatataaa
      421 aggcatattc agtttatttt ttctatttgc cttccttttt atctttttct tttactattc
      481 agtcaggcaa aacaagcagg aattgatcaa ttggcgcctg actggtcttt ctaaaaccaa
      541 attattcctt tttattttct ggcagctgtt ctttcctctc tttctttgtt gtatcttggt
      601 tttattgtgg atcgtcagct tccagtcagt ttatgaagcg cttcttcaaa ggatcaattt
      661 tcttgtctta aagactactg aactgccaga tatccgtgat atcttgactt cggtaagcgg
      721 acttacaatt ccgatggatc aacagacttt ttttaccatc gatttccaaa atgatctttt
      781 tttcacagat atacttaagg gatttgccca aactcttatt gggctcagtg gatgctgtct
      841 cattcttagt ctattccctt tcactttttt tatccatcat ttgcaaagta ggaggcctgg
      901 acgtaatgaa acctgaatat ttgattcatg ctgaacactt gaccgttatt ttgtgtcctc
      961 tcgaaaaaca gcataaaata ttggagcact tgaaaaaaga ggttcttgtt gcaaaactgg
     1021 ataattttgc gatcatccaa aaaaattggc cgatgtttcc ttatctgaat cttaaagacc
     1081 atgtcctgtt ggatgtaccg gaaaaagaaa tcaaacaaga tcgtttggcc tatcaagaaa
     1141 aacttgatat ctctccttcc ttgcttaatt gtgcggcagc tgagttgacg tcttttgaaa
     1201 aagtaaagct gcaattactt catgccttgc tttccaagcg aaacaatatt gttattgaag
     1261 atacatttga tgaacttagt gtattggaga tccaagagct actccacttg ctttcttatt
     1321 tagctcatga agaaaatcaa ggtatcttac tctttactca tgatgctact attgctcaaa
     1381 gtccttatat tgatcgttta gagcccgcgg gctaaatcaa tcattttata gtaaaaacaa
     1441 gcggtataga agatcgattc atgatctttt ataccgcttg ttttttactc ttttttgatt
     1501 tctacgtcag gcaaacgaac agcgaatttt gttccttttc ctagttcgct ttctacttct
     1561 aattttcctt tatgcaagcg tacaagttgc tgcacgattg gtaaacctaa tcctgattca
     1621 ccatattttg tattttttct tgaaggatct actttataat aacgatccca gatacttttc
     1681 atttgttgtt cagacattcc aattcccgta tcttcaatcg tgatgatcgt ttcaagatag
     1741 cctttttcta aagtaatcgt gatttggccg ttttcagtaa actgtatcgc gttttgaata
     1801 atattgacca tgatttggac aaatcggtca taatcagcgt aaacatcaat atcatcaacg
     1861 gctttcaatg tcaatgtatc tcctgctgct tctgctttag cttctaactg tgcaacaata
     1921 tttttcaatg tttctgttcc attgaatttt ttaatgacca tactgatttg attcgtacgg
     1981 attttttcat aatccaagtt ttcattcacc aaacggatca gacgctctgt ttcatttttc
     2041 atcaatttaa tcgcgttttc tcgctgattt tcagggattg cattgtattc taacccttcc
     2101 agaagtccgt tgattgtcgt aagaggtgtt ctcatctcgt gagaagcatc tgccataaat
     2161 tgtcttcgac gattttcttg ttcttcaatt tctgcttgag attctttcaa tgaattcgtc
     2221 attttattga aatcatctgc taactcatca aattcatctt tgtcatgtac ggggagctgt
     2281 acatcaaaat taccattcgt cacttctttc gtcgcattcc ttaaccgatt gatacgctta
     2341 acttggaatg ctgcaaaagc atagctggca ataactgcaa cgatactgga aaaaataaat
     2401 cctttgaaca ggttcagtgt aattggacga acgctgttat cgatatttcg cgcaggttga
     2461 ctaactacaa gtgctccata gaattcatga ttcaaattaa atggcacaag tgcgtaagag
     2521 gtcgcctgtg cttgtcctaa aatattttta ttcgatgtga atttttcttg acgtccattc
     2581 ctcagatttt tccattgatc agctgttaag gtaaaattca gtaaagctgt attagtcgga
     2641 taaatgacac gttcgttttt atcgataaat ataaagttca cattttgttc tgtcagtact
     2701 tgctctgtca gcagcaatgc attttgaaac gcctgatctt gactaaactg cgggagcgta
     2761 tcggcatagg tttgcgttgt cttttcaact gattcagcat atccaaacag ttgctggtaa
     2821 ttgttttctt caatcgtttg ttttgtcagt tgtgtaaaag aaactccaac gatcaataag
     2881 atcaacgcga ccattccgca aaaagctaag agttgctgat acaaataacg cattaggcaa
     2941 caccagaatc atcgaatttg tagccgactc cccaaacagt ttggatgact tgtggtccga
     3001 ccttttcgat tttttgtcgt aatttcttga tatgggcgtc cactgtccgt tcatcaccaa
     3061 agtactgata atcccagact aattcaagca actgctcccg agagaatact tgacgtggtt
     3121 tttttgctaa agtaaacaat agatcgaact ctttaggcgt cagtccttca attggccggt
     3181 tgtccagata cgcttctcgt gttttcgtat tcatcttgaa atgactagtc tcgatatcaa
     3241 aatgatcatc tgaaactgct gcttcttctc ttgcttctgc caactcacta cggcgatgca
     3301 aagctttcat tcgagcaata agcgtcagag gactgaaagg ttttgtgaca taatcatctg
     3361 cccccatctc taagccgatc acctgatcgc tttcagaatc tctagctgtc agcatgataa
     3421 tcggcacagt acttgaaact ttgcggatct ctcttcctac tagcataccg tccagtgtgg
     3481 gcaaattcag gtctagtgta atcatatccc aatgttgtgg gttttctaaa aaggcatcga
     3541 gcccttcttt tccatcatac ttgaaagttg cttcccaacc ttcatttaag aaaaacatct
     3601 gcatcatttc agaaacagat tgattatctt caatcattaa aatattcatt atcgttccct
     3661 ccagtttcca ggtcatattt ctgtaatttc ttttctgtca taataaaaat aggcataatt
     3721 ggaaatacta gcagaagcat ttcaatcaga aaataattcg tatgcccaga tgtctttaaa
     3781 taatagccga tcaatgccat cagtaagccc ataagaaaaa accagtttcc gcttgtcttt
     3841 tgagccagcc gccaatgagc gtctgttttt gcggcaagag gcgaatgata cccataaaaa
     3901 ggcagatttc cttttgaggg cagaatccga aaaagactgc caattattaa gaataagata
     3961 ccaatactga aaaaaatcat tctttccctc ctaaattctc ttcttatagt atactctaaa
     4021 ttgttgactg aaccaatatg ttcaggaatt cttcacgaaa ggtttgtctt ttgttcattc
     4081 tttgttaaga taaacttatt ccaataaaaa aggagtttta tttgtgtcaa attatcgtgc
     4141 aatcactttc tttgatcttg atggaacatt actagatgcg aaatcaaaaa tcacacccga
     4201 agtggcaaaa gctatgaacg cattaaaaga aaacaatgtt ctccccgtca tcgctacagg
     4261 acgtacagaa gcagaaatcc actctatcat ggaagatgcg ggcattactt ctgcggtcac
     4321 catgaatggt tctttcattc gagtagacgg cgaagaaatc tattctcaaa cattttcttc
     4381 agaagaatgt caaaaaatgt atgatcatgt acagttgaac ggtcatgaac tttcttacta
     4441 taacgatcag aaaatctggt gtaccggtca tagccaaaca atgatcaatg cttacgactt
     4501 cattcattca gatgttccgg aaattgatcc tttaggcttt aaagaaaaca cagtaaatat
     4561 gttgctgatc ttatctcaat caggtgacga atactatcac gaacattttc ctgagctaac
     4621 tttttatcgg aatggtcctt actcgatcga tacagtgaag aaaggaatct caaaaggggc
     4681 aggtgtcaaa cgtctgcaaa aagaacttca gctggaaaaa gttcctactt ttggatttgg
     4741 cgatggtccg aatgattttg ccttgttgga agcttgcgac aacaaaatcg ctatggacaa
     4801 cgcctatgac ggattaaaag aactttctac ctttatcaca aagaaaaata cagaaggcgg
     4861 aattgtccac gcattgaagt attttgatct gatttaagat ctttttttga agctacctct
     4921 tttcttaaga aaatcgctta ttttttctta agaaaggggc agttattata taaataatgg
     4981 gatatgattc gcttttttat tgaatttatc ccaatatatg ctatactaat tttgtatgaa
     5041 aaatacacgt aacccttgtt agctaacggg gacgttacgg attcgacagg cacagtcgag
     5101 cttgaattgc gtttcgtagg ttacgtctac gtaaaaacgt tacagttaaa tataactgct
     5161 aaaaacgaaa acaactctta cgctttagct gcctaaaaac agttagcgta gatcctctcg
     5221 gcatcgccca tgtgctcgag taagggtcct aactttagtg ggatacgttt caactttccg
     5281 tctgtaagtt gaaaaagaga acatcagact agcgatacag aatgcctgtc actcggcaag
     5341 ctgtaaagtg aatccttaaa tgagttgact atgaacgtag atttttaagt ggcgatgtgt
     5401 ttggacgcgg gttcgactcc cgccgtctcc atatatgtat ggttgagaca gataaacatg
     5461 tatgaaaaac gttgttaaat caacgttttt ttattttggt caaggagaga aaagtagaga
     5521 aatacaaaat tttttgcatt gattttgcat tcaaaaaaac attcaaacat ttagaaatcc
     5581 ccaatacgta ttcaggaaaa tctattttaa ggtttacaaa aagaactttt gttcgtacac
     5641 tctttttgag gtgaactttt atgctgatgg aaggaaaaac acaattatgg tttaagcatg
     5701 ttccttcaaa taagtttttt taattattat ttgtcaaatt aag
//
LOCUS       DAPBBR010000102         5699 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPBBR010000102 DAPBBR010000000
VERSION     DAPBBR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.108"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="RD488_002644"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="RD488_002644"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="RD488_002645"
     tRNA            203..276
                     /locus_tag="RD488_002645"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="RD488_002646"
     tRNA            316..405
                     /locus_tag="RD488_002646"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="RD488_002647"
     tRNA            420..491
                     /locus_tag="RD488_002647"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="RD488_002648"
     tRNA            507..579
                     /locus_tag="RD488_002648"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="RD488_002649"
     tRNA            589..661
                     /locus_tag="RD488_002649"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="RD488_002650"
     tRNA            697..772
                     /locus_tag="RD488_002650"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="RD488_002651"
     tRNA            774..854
                     /locus_tag="RD488_002651"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="RD488_002652"
     tRNA            861..934
                     /locus_tag="RD488_002652"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="RD488_002653"
     tRNA            937..1009
                     /locus_tag="RD488_002653"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
     gene            1021..1092
                     /locus_tag="RD488_002654"
     tRNA            1021..1092
                     /locus_tag="RD488_002654"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1053..1055,aa:Gln,seq:ttg)
     gene            1138..1208
                     /locus_tag="RD488_002655"
     tRNA            1138..1208
                     /locus_tag="RD488_002655"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1170..1172,aa:Cys,seq:gca)
     gene            1229..1313
                     /locus_tag="RD488_002656"
     tRNA            1229..1313
                     /locus_tag="RD488_002656"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1263..1265,aa:Leu,seq:caa)
     gene            1375..1447
                     /locus_tag="RD488_002657"
     tRNA            1375..1447
                     /locus_tag="RD488_002657"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1408..1410,aa:His,seq:gtg)
     gene            1457..1528
                     /locus_tag="RD488_002658"
     tRNA            1457..1528
                     /locus_tag="RD488_002658"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1489..1491,aa:Gln,seq:ttg)
     gene            1546..1630
                     /locus_tag="RD488_002659"
     tRNA            1546..1630
                     /locus_tag="RD488_002659"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1580..1582,aa:Leu,seq:caa)
     gene            1885..2760
                     /locus_tag="RD488_002660"
     CDS             1885..2760
                     /locus_tag="RD488_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7658658.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            2864..3628
                     /locus_tag="RD488_002661"
     CDS             2864..3628
                     /locus_tag="RD488_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HDT7658659.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            3615..5057
                     /locus_tag="RD488_002662"
     CDS             3615..5057
                     /locus_tag="RD488_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7658660.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            5068..>5699
                     /locus_tag="RD488_002663"
     CDS             5068..>5699
                     /locus_tag="RD488_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HDT7658661.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIY"
BASE COUNT         1720 a          965 c         1287 g         1727 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
     1081 cagctacccc agtttctata atttattctt tattttatag attgataata gtataatggc
     1141 ggtatagcca agtggtaagg cagaggtctg caaaaccttc atcaccggtt caaatccggt
     1201 taccgcctta gtactaataa atcaacttgc cggcgtggcg gaattggcag acgcgctgga
     1261 ctcaaaatcc agtgcccgtt gagggcgtgc cggttcgacc ccggccgccg gtattgacta
     1321 agatgtcttc atcttagttt tttattgaga aattaaataa catcttttat gatggcgaat
     1381 gtggcgaagt ggttaacgca ccggattgtg gctccggcat tcgtgggttc gattcccatc
     1441 attcgccctt tattcttggg gtatagccaa gcggtaaggc aagggacttt gactccctca
     1501 tgcgttggtt cgaatccagc taccccagtt attattttta aatttgccgg cgtggcggaa
     1561 ttggcagacg cgctggactc aaaatccagt gtccgttgag gacgtgccgg ttcgaccccg
     1621 gccgccggta taattatcaa tatagcaact ttcttataga gagttgctat attttttttg
     1681 tttttatgta attacctcca aatcaattcg atacaagtat tatcataaaa cgagtaaaaa
     1741 agatattgat aacgctttta ttatgtgtta aactattttt gtaaattatg tagggtgcta
     1801 ctattcaatt aggcacgacc taagaaaggg ttctttctta ggtcgttttt tgtctttaaa
     1861 aattgtttgg agacaaaaat atgtatgaag gagtctgcaa gttgttttgt tttatcatat
     1921 agaggaggtg aattaacggt gtatgtgatg aaaaagctga atcataatgc tgtattgatc
     1981 gatgacgatg gaatagaaaa aattgcgatg gggaaaggga ttggcttttc tgctaaagtg
     2041 agtaagccat ttgatgttga ggatgctgac aaattatttg tattagattc taaagaaaag
     2101 atcaaacgat tcagtgagat agtctcgcag attccaatcg aatttatgga ttttgcggaa
     2161 gaagtgattg aactgataac agctaggatc tcctctccat tagattcaaa tatctatatt
     2221 acattgacag atcatattta ttttgctatt caacgaaaaa gagaagatag agatgtcaca
     2281 gcaattatgt tgccagaaat gagattcctt tatccaaatg aatatgatat agcagtagaa
     2341 gtggtcgagc gaatcaatca tcgatatcaa accgagttag ggtcaaatga agtaggattc
     2401 atcactatgc atatcattaa tgctgagcta ggagagccta atagtttaaa gagcttaaaa
     2461 atagtagaaa tgacgaccac gattttgtcc catctagaaa aatcctattc aaacgtttat
     2521 gataaagaat cactgactta tcatcgctta atggttcata tcaaattcct ggttaaacgc
     2581 ttgatttatc aggaagaaac gccagtagaa aatattggtt tttttactga aacatttaaa
     2641 catagcaaag cgtattgtac agcactaaag attaaagata tcatcgaaca gcaatttcaa
     2701 cttgccattc aagaaaatga aatcatctat ttggcaattc atctagcaag aatctattaa
     2761 aataagggcg taactatcta taggcgcaac caaatgacac atagtaaatg gactatgatt
     2821 atttggttgc gcctatttta gtagaaaaaa gaaggagaat gaaatgggaa aagtgatttt
     2881 taattcggat gattttggct atagccatgg tgtgaattat gggattatgg atgcttatca
     2941 gcgaggaatt ttgacatcaa ctacattgat ggcaaatatg ccgggtttcg agcatgctgt
     3001 gaaactaaga aaggaaatgc ctaggctagg tgtaggagtc catttaacat tgacgtgtgg
     3061 caaaccactc ctcaaaactg tcgatactct tatcgaaagc ggagagttca gatccttatc
     3121 ttattatcag catccattta acattgacaa agatcaactg tatcaggaat ggaatgctca
     3181 gattcaaaaa atttatcatg cggggatcat accaactcat ttagacagtc atcatcatac
     3241 tcatactttg gatgaaaatc aggaggtagt tgttacatta gcaaaaaaat atgatttgcc
     3301 ggttcggagc aactttgaac gaaaagatga agttcgtcat gtcgattatt ttgagccttg
     3361 tttcgatgtc gtaggagaaa ctgatgaaaa aaaacgacaa atcaatacga gtgtggaaga
     3421 atatttggca agtttactca tgatattgag agaagataaa acgatcgaag tcatgtgtca
     3481 cgcagcgtat ttggatcagg aattgttaaa tggttcaagt tttgtgtatc ctcgtaccca
     3541 ccaagtcgaa tttttaattc attcagcatt tgctcaaaaa gtgaaaaatg atcctttgat
     3601 tgagttagta acatatgagg atatttaata gaggaggaat aaaaatgaat gttaaatcaa
     3661 atgtgcagaa gcttggaaga gcgatgctac ttccagttgc agcgatgcca ttagcgggat
     3721 tgatcatgcg tttatcagct gacgatatgc tgaacatccc agtaattggt gcagctggaa
     3781 atgccgtttt tggaaacttg gatatcttat ttgctatagg agttgcaatc ggttttgtca
     3841 aaaataagga caaaggaata cctgcactta ctggtttttt agcgattgct accttgaaaa
     3901 aaggcttaga aattatggac ccagaagtga atatggggat ttttggtgga attatttccg
     3961 gtttagtagc ggcatggacg tataatcgct ttaaagaaca aaaattacca gtagtttttt
     4021 cttattttgc gggcgaaaaa ttcccattga ctatggtgat gattctacaa acaatcgcag
     4081 ctgttttttt gggctttatc tggccgctca tccaaattgg gattgataat tttgcaaaac
     4141 tgctcgttga tatgggagca ttaggtgtgg ggatatttat gtttttgaat cgtttgctga
     4201 tcccctttgg actgcaccat gtgttgaata cgtatattta ttacgattta ggaagctata
     4261 catctcctag caaggaagtt ttcagaggag agatgacacg ctttatcaac ggagatcctc
     4321 aggctggact gtttttatca ggtttttttg tagtaatgat gtttggtata ccagctatat
     4381 gtctagctat ctataaagca gcttataaag aaaataaaga gatggtcaaa ggaatcatgg
     4441 gaagcggtgc aggaacttca tttattgcaa atatcactga gcctgttgaa tttagtttca
     4501 tgtttctttc tcctatgttg tacgtgatcc atgcactttt tgccggttta gcagggattg
     4561 tctgttactt attcaatata cgaattggtt ttacattcgg agcatgtatt gttgattatc
     4621 tcatcaattt tcgaatcgct accaatgcta ttttgattct tccaatcgga attttctttt
     4681 ttgccttgta ttacgttact ttttattatt tgatcaataa gagaaacatt cagacattag
     4741 gacgtgaagc taaggcagag tttggcaatg aagtaacctt agaagaaaca gagttagggt
     4801 tagcaagtaa aaattatgaa tatatggcaa caaaaatgct acaagcgttt ggaggaaaag
     4861 ccaatatcct ggatgtctat agttgtaata cacgcctacg ggtagaggta gtggatccca
     4921 ccatggtcga ggaacagcga atcaagcaat tagggataag cgggatcatt aaaccaactg
     4981 aaaaaaatta tcaaattatc atcggcttag aagtgactta tgttatggca gaattcaata
     5041 aattattaga agaatagaaa ggaaaagatg atgatgaaaa aacagattat cactatagct
     5101 ggaggcggga gtacgtatac accaggaatc gttcaagcca ttttgaacaa tgaaaaacgg
     5161 ttgccattat ctgaaatacg tttatatgat attgatgaag aaagaaatat ggatatgtac
     5221 ttgattgtta aatttatgct gaaaagaaaa ggtttttcaa atattcgcat tcgtgcaacg
     5281 gatgatccaa agcttgcttt tacaggatgc gattttgttt tctcacaaat tcgtgttgga
     5341 ggattggaga tgcgagaaaa ggacgaaaag attccactta aacatggatt agtaggacaa
     5401 gaaacgtgtg gactcggagg atttgcttat gggatgcgct caatcaaagg tttattggaa
     5461 attgtcgatc atatacaaga ctatgccccc aaagcatgga ttttgaatta tacaaatcca
     5521 gagtcgatcg tttctgaagc tgttcgtcgt aaatatccga atgtaaaaat gattaatgcc
     5581 tgtgatatga ctatttcaat tgaagaaacg attgcagtga attacggtta tgatcgtaag
     5641 aattggatcg ttacgtatta tggtttaaac cactttggct ggtatacatc gatttatga
//
LOCUS       DAPBBR010000103         5694 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPBBR010000103 DAPBBR010000000
VERSION     DAPBBR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.109"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(46..2970)
                     /locus_tag="RD488_002664"
     CDS             complement(46..2970)
                     /locus_tag="RD488_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDT7658662.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3116..3691
                     /locus_tag="RD488_002665"
     CDS             3116..3691
                     /locus_tag="RD488_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658663.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3905..4600
                     /gene="vanR"
                     /locus_tag="RD488_002666"
     CDS             3905..4600
                     /gene="vanR"
                     /locus_tag="RD488_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7658664.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4578..>5694
                     /locus_tag="RD488_002667"
     CDS             4578..>5694
                     /locus_tag="RD488_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7658665.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVEL"
BASE COUNT         1754 a         1078 c         1077 g         1785 t
ORIGIN      
        1 ctaaaatact ttgttttttt acctgtctac ttgacagggg gcagttcact ctgagttaaa
       61 atggtattct cctagtaaat taatatgttc ccaacctaag ggcgacatat ggtgtaacaa
      121 atcttcatta aagctacctg tccgtttttt atattcaact gctgttgtta ggtggagagt
      181 attccaaata cttatagcat tgataattat gtttaaagca ctggctcttt gcaattgatg
      241 ctgtatggtg cgttctctaa gctcaccttg ttttccgaag aaaatagctc ttgccaatcc
      301 attcatggct tctcctttat tcaatcctct ttgtattttt cttcttaatg attcatccga
      361 tatataattc aaaataaaga tcgttttttc tattcggccc atctcacgta aggctgtagc
      421 taagctgttt tgtcttgaat aggaacctag cttccccata ataagggatg ctgaaactgt
      481 tccctccctt atagaatgag ctaatcgcaa aacatcctca taattttctt taatgacctt
      541 tgtatttatt tgtccacgta aaatggcttc tagttttgga tactcacttg ctttatctat
      601 cgtaaataat tttgagtccg ataaatccct tattcttggg gcaaatttaa atcctaataa
      661 atgagtcagt ccgaatattt ggtcagtgta accggcagtg tctgtataat gttcctctat
      721 gtttagatcc gtctcatgat gtaacaaacc atccaaaaca tgaatcgcat ctcttgaatt
      781 agtatgaata atctttgtgt agtaagaaga gaattgatca cttgtaaatc ggtagatggt
      841 ggctcctttt ccagttccat aatgtggatt tgcatctgca tgtagtgatg aaacacctag
      901 ctgcattctc ataccatctg acgaagatgt tgtaccgtcg ccccaataga aaggcaattg
      961 taatttatga tgaaagttta ctaatatggc ttgggcttta ttcatggcat cttcatacat
     1021 gcgccattga gatacattgg ctagttgctt atatgtaagt ccgggtgtgg cttcggccat
     1081 cttgctcaag ccaatattca ttcccattcc taaaagggca gccatgataa tgattgtttc
     1141 ttccttatct ggttttcgat tattggaagc atgagtgaat tgctcatgaa atcctgttat
     1201 atgggccaca tccatgagta aatcagttaa ttttattctt ggtagcatct gataaaggct
     1261 tgcactaaat ttttttgctt cttctggaac atctttttct aagcgtgcaa gtgatagctt
     1321 tcctttttca agagaaaccc catctaactt attggaattg gcagctaacc actttaacct
     1381 ttcattaaag ctgctggttc tctccgttat ataatcttcg aatgataaac taactgataa
     1441 tctcgtattc cccttcgatt gattccatgt atcttccgaa aacaaatatt cctcaaaatc
     1501 cctatattgt ctgctgccaa caatggaaac atctcctgcc cgaacatgct cccgaagttc
     1561 tgttaaaaca gccatttcat agtaatgacg attaattgtt gtaccatcat cctcgtataa
     1621 atgtcttttc catcgttttg aaataaaatc cacaggtgag tcatcaggca cttttcgctt
     1681 tccagattcg ttcattcctc ggataatctc aacagcttgt aaaagtggct catttgcctt
     1741 tgtagaatga aattccaata ctcttaatag cgttggcgta tattttctta gtgaataaaa
     1801 ccgtttttgc agtaagtcta aataatcata gtcggcagga cgtgcaagtt cctgagcctc
     1861 ttctactgaa gagacaaagg tattccattc aataaccgat tctaaaacct taaaaacgtc
     1921 taatttttcc tctcttgctt taattaatgc ttgtccgatg ttcgtaaagt gtataacttt
     1981 ctcatttagc tttttaccgt tttgtttctg gatttcctct tgagccttac gaccttttga
     2041 taacaaacta agtatttgcc tatcatgaat ttcaaacgct ttatccgtta gctcctgagt
     2101 aagttgtaat aaatagatgg ttaatatcga ataacgttta ttttcttgaa agtcacggaa
     2161 tgcatacggc tcgtatcttg agcctaagcg agacagctgc aacaggcggt tacggtgcaa
     2221 atgactaatt tgcactgttt ctaaatccat tcctcgtatg tattcgagtc gttctattat
     2281 ttttagaaaa gtttcgggtg aaggatgacc cggtggctct tttaaccaac ccaatatcgt
     2341 tttattggat tcggatggat gctgcgaggt aataatccct tcaagctttt ctttttgctc
     2401 atttgttaga gatttactaa ccgtattaaa tagcttcttt tcagccattg cccttgcttc
     2461 ccacaccatt ctttcaagtg tagtgatagc aggcagtata attttgtttt ttcttagaaa
     2521 atctatgcat tcatgcagta gatgaatggc atcaccattt tccaaagcta attgatgaag
     2581 gtacttaaat gtcattcgat attcactcag ggtaaaagtt acaaagtcgt attcacttcg
     2641 aatttctttc aaatgatccc aaagtgtatt ttccctttga ggataatgat caagcgagga
     2701 tggactaaca ccaatctgtt tcgatatata ttgtatgacc gaatctggga tgcttttgat
     2761 atgagtgtat ggccaaccgg gataccgaag aacagctaat tgaacagcaa atcctaaacg
     2821 gttttcttcc ctccttcgct tattaactat ttctaaatcc cgtttggaaa aagtgaagta
     2881 ggtccccagt atccattcat cttcagggat ttgcataaaa gcctgtctct gttccggtgt
     2941 aagcaattct ctacctctcg caattttcat tcagtatcat tccatttctg tattttcaat
     3001 ttattagttc aattatatat caatagagtg tactctattg atacaaatgt agtagactga
     3061 taaaatcata gttaagagcg tctcataaga cttgtctcaa aaatgaggtg atattttgcg
     3121 gaaaatcggt tatattcgtg tcagttcgac taaccagaat ccttcaagac aatttcagca
     3181 gttgaacgag atcggaatgg atattatata tgaagagaaa gtttcaggag caacaaagga
     3241 tcgcgagcaa cttcaaaaag tgttagacga tttacaggaa gatgacatca tttatgttac
     3301 agacttaact cgaatcactc gtagtacaca agatctattt gaattaatcg ataacatacg
     3361 agataaaaag gcaagtttaa aatcactaaa agatacatgg cttgatttat cagaagataa
     3421 tccatacagc caattcttaa ttactgtaat ggctggtgtt aaccaattag agcgagatct
     3481 tattcggatg agacaacgtg aagggattga attggctaag aaagaaggaa agtttaaagg
     3541 tcgattaaag aagtatcata aaaatcacgc aggaatgaat tatgcggtaa agctatataa
     3601 agaaggaaat atgactgtaa atcaaatttg tgaaattact aatgtatcta gggcttcatt
     3661 atacaggaaa ttatcagaag tgaataatta gccattctgt attccgctaa tgggcaatat
     3721 ttttaaagaa gaaaaggaaa ctataaaata ttaacagcct cctagcgatg ccgaaaagcc
     3781 ctttgataaa aaaagaatca tcatcttaag aaattcttag tcatttatta tgtaaatgct
     3841 tataaattcg gccctataat ctgataaatt attaagggca aacttatgtg aaagggtgat
     3901 aactatgagc gataaaatac ttattgtgga tgatgaacat gaaattgccg atttggttga
     3961 attatactta aaaaacgaga attatacggt tttcaaatac tataccgcca aagaagcatt
     4021 ggaatgtata gacaagtctg agattgacct tgccatattg gacatcatgc ttcccggcac
     4081 aagcggcctt actatctgtc aaaaaataag ggacaagcac acctatccga ttatcatgct
     4141 gaccgggaaa gatacagagg tagataaaat tacagggtta acaatcggcg cggatgatta
     4201 tataacgaag ccctttcgcc cactggagtt aattgctcgg gtaaaggccc agttgcgccg
     4261 atacaaaaaa ttcagtggag taaaggagca gaacgaaaat gttatcgtcc actccggcct
     4321 tgtcattaat gttaacaccc atgagtgtta tctgaacgag aagcagttat cccttactcc
     4381 caccgagttt tcaatactgc gaatcctctg tgaaaacaag gggaatgtgg ttagctccga
     4441 gctgctattt catgagatat ggggcgacga atatttcagc aagagcaaca acaccatcac
     4501 cgtgcatatc cggcatttgc gcgaaaaaat gaacgacacc attgataatc cgaaatatat
     4561 aaaaacggta tggggggttg gttataaaat tgaaaaataa aaaaaacgac tattccaaac
     4621 tagaacgaaa actttacatg tatatcgttg caattgttgt ggtagcaatt gtattcgtgt
     4681 tgtatattcg ttcaatgatc cgagggaaac ttggggattg gatcttaagt attttggaaa
     4741 acaaatatga cttaaatcac ctggacgcga tgaaattata tcaatattcc atacggaaca
     4801 atatagatat ctttatttat gtggcgattg tcattagtat tcttattcta tgtcgcgtca
     4861 tgctttcaaa attcgcaaaa tactttgacg agataaatac cggcattgat gtacttattc
     4921 agaacgaaga taaacaaatt gagctttctg cggaaatgga tgttatggaa caaaagctca
     4981 acacattaaa acggactctg gaaaagcgag agcaggatgc aaagctggcc gaacaaagaa
     5041 aaaatgacgt tgttatgtac ttggcgcacg atattaaaac gccccttaca tccattatcg
     5101 gttatttgag cctgcttgac gaggctccag acatgccggt agatcaaaag gcaaagtatg
     5161 tgcatatcac gttggacaaa gcgtatcgac tcgaacagct aatcgacgag ttttttgaga
     5221 ttacacggta taacctacaa acgataacgc taacaaaaac gcacatagac ctatactata
     5281 tgctggtgca gatgaccgat gaattttatc ctcagctttc cgcacatgga aaacaggcgg
     5341 ttattcacgc ccccgaggat ctgaccgtgt ccggcgaccc tgataaactc gcgagagtct
     5401 ttaacaacat tttgaaaaac gccgctgcat acagtgagga taacagcatc attgacatta
     5461 ccgcgggcct ctccggggat gtggtgtcaa tcgaattcaa gaacactgga agcatcccaa
     5521 aagataagct agctgccata tttgaaaagt tctataggct ggacaatgct cgttcttccg
     5581 atacgggtgg cgcgggactt ggattggcga ttgcaaaaga aattattgtt cagcatggag
     5641 ggcagattta cgcggaaagc aatgataact atacgacgtt tagggtagag cttc
//
LOCUS       DAPBBR010000104         5667 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPBBR010000104 DAPBBR010000000
VERSION     DAPBBR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.110"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            118..1272
                     /locus_tag="RD488_002668"
     CDS             118..1272
                     /locus_tag="RD488_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7658666.1"
                     /translation="MEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSIN
                     GELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQ
                     REMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKE
                     PTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSF
                     QNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKA
                     GTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEY
                     RSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1370..2743
                     /gene="tet(L)"
                     /locus_tag="RD488_002669"
     CDS             1370..2743
                     /gene="tet(L)"
                     /locus_tag="RD488_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7658667.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3307..4569
                     /locus_tag="RD488_002670"
     CDS             3307..4569
                     /locus_tag="RD488_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7658668.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            4814..>5667
                     /locus_tag="RD488_002671"
     CDS             4814..>5667
                     /locus_tag="RD488_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HDT7658669.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT         1954 a          800 c         1165 g         1748 t
ORIGIN      
        1 tatcatggaa gcgcaaaaag caacataggg attgagcagc ttatagaagt gataacgaat
       61 aaattttatt catcaacata cagaaagaag tctgaacttt gcggaaatgt cttcaaaatt
      121 gaatattcgg aagaaagaca acgtcttgca tatgtacgcc tttatggcgg aatcctgcat
      181 ttgcgggatt cggttagaat atcggaaaag gaaaaaataa aaattacaga aatgtatact
      241 tcaataaatg gtgaattatg taaaattgat aaggcttatt ccggggaaat tgttattttg
      301 caaaatgagt ttttgaagct aaatagtgtt cttggagata caaagctatt gccacagaga
      361 gagagaattg aaaatccgct ccctctgctg caaacaactg ttgaaccgag caaacctcaa
      421 caaagggaaa tgttacttga tgcactttta gaaatctccg acagtgaccc gcttctacaa
      481 tattatgtgg attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg
      541 gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct
      601 acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg
      661 ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt
      721 ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca
      781 gttatggaag ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacggat
      841 tgtaaaatct gttttaagta tggcttatac tatagccctg ttagtacccc agcagatttt
      901 cggatgcttg ctcctattgt attggaacaa gtcttaaaaa aagctggaac agaattgtta
      961 gagccatatc ttagttttaa aatttatgcg ccacaggaat atctttcacg agcatacaac
     1021 gatgctccta aatattgtgc gaacatcgta gacactcaat tgaaaaataa tgaggtcatt
     1081 cttagtggag aaatccctgc tcggtgtatt caagaatatc gtagtgattt aactttcttt
     1141 acaaatggac gtagtgtttg tttaacagag ttaaaagggt accatgttac taccggtgaa
     1201 cctgtttgcc agccccgtcg tccaaatagt cggatagata aagtacgata tatgttcaat
     1261 aaaataactt agtgtatttt atgttgttat ataaatatgg tttcttgtta aataagatga
     1321 aatatttttt aataaagatt tgaattaaag tgtaaaggag gaattaatta tgaagtgtaa
     1381 tgaatgtaac agggttaaat acaaccaaat tttaatttgg ctttgcgttt tatctttttt
     1441 tagcgtatta aatgaaatgg ttttgaacgt ctcattacct gatattgcaa atgattttaa
     1501 taaaccacct gcgagtacaa actgggtgaa cacagccttt atgttaacct tttccattgg
     1561 aacagctgta tatggaaagc tatctgatca attaggcatc aaaaggttac tcctatttgg
     1621 aattataata aattgtttcg ggtcggtaat tgggtttgtt ggccattctt tcttttcctt
     1681 acttattatg gctcgtttta ttcaaggggc tggtgcagct gcatttccag cactcgtaat
     1741 ggttgtagtt gcgcgctata ttccaaagga aaataggggt aaagcatttg gtcttattgg
     1801 atcgatagta gccatgggag aaggagtcgg tccagcgatt ggtggaatga tagcccatta
     1861 tattcattgg tcctatcttc tactcattcc tatgataaca attatcactg ttccgtttct
     1921 tatgaaatta ttaaagaaag aagtaaggat aaaaggtcat tttgatatca aaggaattat
     1981 actaatgtct gtaggcattg tattttttat gttgtttaca acatcatata gcatttcttt
     2041 tcttatcgtt agcgtgctgt cattcctgat atttgtaaaa catatcagga aagtaacaga
     2101 tccttttgtt gatcccggat tagggaaaaa tatacctttt atgattggag ttctttgtgg
     2161 gggaattata tttggaacag tagcagggtt tgtctctatg gttccttata tgatgaaaga
     2221 tgttcaccag ctaagtactg ccgaaatcgg aagtgtaatt attttccctg gaacaatgag
     2281 tgtcattatt ttcggctaca ttggtgggat acttgttgat agaagaggtc ctttatacgt
     2341 gttaaacatc ggagttacat ttctttctgt tagcttttta actgcttcct ttcttttaga
     2401 aacaacatca tggttcatga caattataat cgtatttgtt ttaggtgggc tttcgttcac
     2461 caaaacagtt atatcaacaa ttgtttcaag tagcttgaaa cagcaggaag ctggtgctgg
     2521 aatgagtttg cttaacttta ccagcttttt atcagaggga acaggtattg caattgtagg
     2581 tggtttatta tccataccct tacttgatca aaggttgtta cctatggaag ttgatcagtc
     2641 aacttatctg tatagtaatt tgttattact tttttcagga atcattgtca ttagttggct
     2701 ggttaccttg aatgtatata aacattctca aagggatttc taaatcgtta agggatcaac
     2761 tttgggagag agttcaaaat tgatcctttt tttataacag gaattcaaat ctttttgttc
     2821 cattaaaggg cgcgattgct gaataaaaga tacgagagac ctctcttgta tcttttttat
     2881 tttgagtggt tttgtccgtt acactagaaa accgaaagac aataaaaatt ttattcttgc
     2941 tgagtctggc tttcggtaag ctagacaaaa cggacaaaat aaaaattggc aagggtttaa
     3001 aggtggagat tttttgagtg atcttctcaa aaaatactac ctgtcccttg ctgattttta
     3061 aacgagcacg agagcaaaac ccccctttgc tgaggtggca gagggcaggt ttttttgttt
     3121 cttttttctc gtaaaaaaaa gaaaggtctt aaaggtttta tggttttggt cggcactgcc
     3181 gacagcctcg cagagcacac actttatgaa tataaagtat agtgtgttat actttacttg
     3241 gaagtggttg ccggaaagag cgaaaatgcc tcacatttgt gccacctaaa aaggagcgat
     3301 ttacatatga gttatgcagt ttgtagaatg caaaaagtga aatcagctgg actaaaaggc
     3361 atgcaatttc ataatcaaag agagcgaaaa agtagaacga atgatgatat tgaccatgag
     3421 cgaacacgtg aaaattatga tttgaaaaat gataaaaata ttgattacaa cgaacgtgtc
     3481 aaagaaatta ttgaatcaca aaaaacaggt acaagaaaaa cgaggaaaga tgctgttctt
     3541 gtaaatgagt tgctagtaac atctgaccga gatttttttg agcaactgga tccaggagaa
     3601 caaaaacgat tttttgagga aagttataaa ttattttccg aacgatatgg caagcaaaat
     3661 attgcttatg caacagttca taatgatgag caaacccctc acatgcattt aggtgttgtg
     3721 cctatgcgtg atggaaaact gcaaggaaaa aatgtgttta atcgtcaaga actgttatgg
     3781 ctacaagata aattccccga gcatatgaaa aaacagggtt ttgagttgaa gcgtggtgaa
     3841 cgtggctctg accgtaaaca tattgagaca gctaaattta aaaaacaaac tttggaaaaa
     3901 gagattgatt ttctagaaaa aaatttagca gttaaaaaag atgaatggac tgcttatagc
     3961 gataaagtta aatcagattt agaagtacca gcgaaacgac acatgaaaag tgttgaagtg
     4021 ccaacgggtg aaaagtccat gtttggtttg ggaaaagaaa taatgaaaac agaaaagaaa
     4081 ccaaccaaaa atgttgttat atcggagcgt gattataaaa acttagtgac tgctgcgaga
     4141 gataacgata ggttaaaaca gcatgttaga aatctcatga gtactgatat ggcgagagaa
     4201 tataaaaaat taagtaaaga acatgggcaa gttaaagaaa aatatagtgg tcttgtagag
     4261 cgatttaatg aaaatgtaaa tgattataat gagttgcttg aagaaaacaa gtctttaaag
     4321 tctaaaataa gcgatttaaa gcgtgatgtg agtttaatct atgaaagcac taaggaattc
     4381 cttaaggaac gtacagacgg cttaaaagcc tttaaaaacg tttttaaggg gtttgtagac
     4441 aaggtaaagg ataaaacagc acaattccaa gaaaaacacg atttagaacc taaaaagaac
     4501 gaatttgaac taactcataa ccgagaggta aaaaaagaac gaagtcgaga tcagggaatg
     4561 agtttataaa ataaaaaaag cacctgaaaa ggtgtctttt tttgatggtt ttgaacttgt
     4621 tctttcttat cttgatatat atagaaataa cgtcattttt attttagttg ctgaaaggtg
     4681 cgttgaagtg ttggtatgta tgtgttttaa agtattgaaa acccttaaaa ttggttgcac
     4741 agaaaaaccc catctgttaa agttataagt gaccaaacaa ataactaaat agatgggggt
     4801 ttcttttaat attatgtgtc ctaatagtag catttattca gatgaaaaat caagggtttt
     4861 agtggacaag acaaaaagtg gaaaagtgag accatggaga gaaaagaaaa tcgctaatgt
     4921 tgattacttt gaacttctgc atattcttga atttaaaaag gctgaaagag taaaagattg
     4981 tgctgaaata ttagagtata aacaaaatcg tgaaacaggc gaaagaaagt tgtatcgagt
     5041 gtggttttgt aaatccaggc tttgtccaat gtgcaactgg aggagagcaa tgaaacatgg
     5101 cattcagtca caaaaggttg ttgctgaagt tattaaacaa aagccaacag ttcgttggtt
     5161 gtttctcaca ttaacagtta aaaatgttta tgatggcgaa gaattaaata agagtttgtc
     5221 agatatggct caaagatttc gccgaatgat gcaatataaa aaaattaata aaaatcttgt
     5281 tggttttatg cgtgcaacgg aagtgacaat aaataataaa gataattctt ataatcagca
     5341 catgcatgta ttggtatgtg tggaaccaac ttattttaag aatacagaaa actacgtgaa
     5401 tcaaaaacaa tggattcaat tttggaaaaa ggcaatgaaa ttagactatg atccaaatgt
     5461 aaaagttcaa atgattcgac cgaaaaataa atataaatcg gatatacaat cggcaattga
     5521 cgaaactgca aaatatcctg taaaggatac ggattttatg accgatgatg aagaaaagaa
     5581 tttgaaacgt ttgtctgatt tggaggaagg tttacaccgt aaaaggttaa tctcctatgg
     5641 tggtttgtta aaagaaatac ataaaaa
//
LOCUS       DAPBBR010000105         5590 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPBBR010000105 DAPBBR010000000
VERSION     DAPBBR010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.111"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(57..608)
                     /gene="raiA"
                     /locus_tag="RD488_002672"
     CDS             complement(57..608)
                     /gene="raiA"
                     /locus_tag="RD488_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDT7658670.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(736..1455)
                     /locus_tag="RD488_002673"
     CDS             complement(736..1455)
                     /locus_tag="RD488_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDT7658671.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(1452..2765)
                     /locus_tag="RD488_002674"
     CDS             complement(1452..2765)
                     /locus_tag="RD488_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7658672.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(2846..3166)
                     /locus_tag="RD488_002675"
     CDS             complement(2846..3166)
                     /locus_tag="RD488_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7658673.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(3274..3561)
                     /locus_tag="RD488_002676"
     CDS             complement(3274..3561)
                     /locus_tag="RD488_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658674.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            3688..4332
                     /locus_tag="RD488_002677"
     CDS             3688..4332
                     /locus_tag="RD488_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDT7658675.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(4391..5098)
                     /locus_tag="RD488_002678"
     CDS             complement(4391..5098)
                     /locus_tag="RD488_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7658676.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5318..5488)
                     /locus_tag="RD488_002679"
     CDS             complement(5318..5488)
                     /locus_tag="RD488_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658677.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
BASE COUNT         1610 a         1175 c          966 g         1839 t
ORIGIN      
        1 ttgcggcagc tgtcagtagc tgctgcaagt tttcgttgtt atttaagtaa ggctgatcag
       61 tctgtttcaa tcagtccgta ttttccatct ttacggcggt aaacgatact tgtaccattt
      121 gtttctgcat cttcaaaaat aaagaagtta tgtcccagca tgttcatttg taagactgct
      181 tcttcactat ccattggttt caatgaaagg cgtttcgtac gtacgatatc taattcagaa
      241 tcattttcgt tttcgtcctc ttcattgaat aaagcagcag catctgcagt attcatgccc
      301 gtttcacggg atttacgatt aatttttgtt ttgaatttgc ggatttggcg ttccaattta
      361 tcaacaacca aatcgatact tgcgtataaa tctggagaag tttcttcggc acgtaataca
      421 agataaggta atgggatcgt tacttccact tttgctgttt tttctgtata aacttttaag
      481 ttcacatgcg ccgttgcatc gggtgcgtca ctgaaatagc gttctagttt gcctactttt
      541 ttctcaacgt agtcgcgaat cgcttcagtt acttcgatat tttcgccgcg tacattatat
      601 ctaaacataa aaattacccc tttcgtctac cacaatcaag aaggagaagg accactcttt
      661 ccctcttctt aattctatta tatcgaactc taggttattt gcaaattaaa tcgctatcaa
      721 atttccacat ctaattcatc tcgccaaaga aatggttcgg atgattttcg gctgtgcgac
      781 ctgcaaacaa tctgctgcgt ggaaaagagt ctgtcctgtt gtatagacat catcaataat
      841 caatattttt ttattttgta tcttagaaaa ggtgactgca agttcaaaag gttgaggcat
      901 ctccaatctt tcctttcgcg tgttttttgc ttgagccagc agatgcttct ctcttttgag
      961 tagcatctga aaaggaattc ttgctgcttt caacatctcg cttacttgat tgaatcctct
     1021 ttctgttcgc cttttttcag ataaaggtat tggacaatag atgtatgtcg ggtattcttt
     1081 ttttatctgc gtccatttat atgcaaaggt gcctgctagt cggatatctc ccataaactt
     1141 gtattgattg agccaggcct tcatattttc atcgtacaca aaaaaggcac ggtgctgaaa
     1201 atcataggtc ggatatttct tcttccattc ttgacagtca ctgcagtaaa cgggaataga
     1261 ctttactttc tttttcgtac tctctagatt gaaatggatt ggtttttgac agccagaaca
     1321 gcctcttgtt tccaataaat gaaattgtgc gcgacaaact gaacaagtct gaggtaatct
     1381 gtatttcgaa acaccaataa tctcgctgaa tgttaaattt tggaagatat ctttactgca
     1441 gcaactgcac ctcacagcat cttcttccct tcttcattca tttctttgat ttcctgacaa
     1501 gcttttcgaa tagctgcagt tttttcttca tagaaaaagt atacttgact gttcgtataa
     1561 ggccctttac gatcggctct tcctgcgatt tgtaccaaag aagatttagt aaaaaccgga
     1621 tgatccgctc ctaaaacgat aacggatatt ctttcaaatg tgactccacg ttcaaggatc
     1681 atcgtggtta acagtatatc atattttgct tctcgcattt tctggacttt ttccgcccgc
     1741 tgattgtctc ttgaagaaac atctgtgatc tcatatctcg gaagagcctc ttgaagtgtg
     1801 gctttcaaac gatgcatcat cgtgatactt ggacaaaata aaaggatatg gttttcttta
     1861 attaattgat gaatgatccg caccaaagat tttatcttct tcttgttctt gcatttttgt
     1921 cgccaattat tcatgaaaac caagacgggt tcaggaagca aacgccgatg aaagcgtaaa
     1981 gcaagtttgt ggatgtcaaa cgtctgcttg atttccttta gtaacttttt atcaggtgtg
     2041 gcacttaagt agatgaatcg tccgtctggt ttaatcgctg tttgcacagc atgagctaat
     2101 cctgcatccc cgttataagg aaacgcatcg atctcatcga tcactattaa atcaaaggac
     2161 cgataaaaac ggtatagctg atgaatcgta cagataacaa aagaagtaaa ggtataagcc
     2221 gttgctgtat tcccatggag caacgtgatt ttttcttctg gaaaaacata acgatagcgt
     2281 aaaaacaatt cattacaaac atcgactcgc ggtgtacaaa tcgctactct tcctccagct
     2341 tttaaagttt ccactaaaat aggataaagc atctctgttt tccctgcacc tgttacagcc
     2401 caaataagat gatgtctttt ttctgaatgg caaagtattc tctttgagat ttccgtttgt
     2461 ttttcagtaa gctgtcctgt ccaaaaaaag acgacttctc gaggttttgc ttcaggctga
     2521 tcaaacaaat ataaatcttg ttgagtgtcg catcgcccta aatatagaca atgtgtacaa
     2581 aaataaccgt aatctgcaag ctgtccatca atgacggacg tcctcattcc acagcgatga
     2641 caaagaatcc agttgcccaa acgttccact gctgcgatct tctcataatt tggtaaattt
     2701 acctcctcac agtctattgc ttcaatatct ctcgtcagaa gccttctacc ccaaaaatga
     2761 ttcatattct tcgccctaaa aaaatatacg aaaaaacaag cgatctattt tttggatcgc
     2821 ttgttcgata gttatactgt tctatttatt cacctatgag cgtgattgct tgatctaaca
     2881 ctttttcgcc attcatcata ccataatcag ccatattgat gacatctaaa ggaatgcctt
     2941 ttggttccag acgtttctca aaatcagctt tcataaagcg aacttgtggg cctaataaca
     3001 acacatccac gtctttattt gcaaggttgt tatctgcgtc agaagcggac acagcgaaaa
     3061 tatccgagtc gattcctttt gcttcagcag ctttttgcat ttttgttact agtaaacttg
     3121 tgctcatacc agccgaacat acaagcatga ttgttttttt agccatactt ttctctcctt
     3181 tttaaaacaa actatgcaaa cgttttcttc gcgtctgtta ctctattata taaaaagaaa
     3241 gaaatttgtc aacgttttct aaacgcggtt tatttaatca aatagccaac tagatttcac
     3301 taatttattg aacacgacat attctttgtc caaattgatg acaactactt catagcctgc
     3361 atttatccag ccataggcac ctttttcagg gtgtttataa tcatttgccc accaatctgt
     3421 actttccctt gctgttttgg gaagtccgtt actgggaaac agcagttcgt caaattgggt
     3481 aaaggtcaac gttacttgag agccgccatt gttcttcaaa taatgcgtaa ttgcatcgta
     3541 ctttttcatt cgttcctgca tccccagatc cacctgcctt tgtctttatt atcgcatact
     3601 acagcaattg cgcaaccgtt acagtgttga aacaacctag aactttattt atactgaata
     3661 aagaaaatga aaaaaagagg tgacaagatg atcgagcgct atcgtacaat aaaagaaaat
     3721 ggacaaagtg agattgagat caaaaaatca cgctttatct gttctcttag acgaatagaa
     3781 tcagaggacc aagcaaaaag tttcattcaa gaaataaaaa aagaacattg gaaagcgaac
     3841 cataactgca gcgccttcat cattggagaa aaaaatgaaa tccagcgaag cagcgatgat
     3901 ggagaaccaa gtggaacggc gggcgtaccg atgttggaag tcctcaaaaa aaatcaactg
     3961 atcaatgtag ctgcagtagt cactcgatat tttggaggaa cgaaactcgg cacaggcgga
     4021 ttaatacgag catacactca tgcggtctct caagcattgt ctgacattgg aatcgtagaa
     4081 ggtaccttgc aacaggagat ctctgtgatg atcacgtatc cgcaactagg aaaattacag
     4141 aattatcttg aactccaaca tttttttata aaagaaatcc aatatactga tcaagttagc
     4201 gtcatctgtg ctgtagatga aaaaagtgct gaccacttta aagaatccat cattgagctg
     4261 ctgaacggac aagtccaatt tgaagagggt tctgtttctt atcacgagca actgataact
     4321 gatcatatat aaaaacaggt gattctgatt ctcttttatt tctaataagg aatcagggat
     4381 cacctgtttt ttatttttcc aaataaaact caaaacgatt tcctacgtat tgcgtacgca
     4441 catactcaaa cggcgtaccg tcttcaaaat aagaaatctg gcgcaaacga agaactgcat
     4501 ctcctcgttt tacctctaaa tagtcagcaa ttttctcaga agccaacaca gcagtaatcg
     4561 tttgattcgc tggaccgatc tttttcccgc ctttttcttc tagcgtgcga tacaacgatt
     4621 cagtaatctc tgctttgctg tagccatcga tcagcttttg tggaacactg gcaacttcaa
     4681 aacaaatagg gacatcatct gcgaaacgaa tacgttccat tcgcaagatc gtgtcatctt
     4741 tactcaagtt tagtttttcc atttcacttg agcttggcga agtcaagaaa taagagattg
     4801 tccgactaga cggtactcga ttttgtgatt ccataatttc tgtaaaactt gttgcaccag
     4861 acattttttc ttgtactttt tctcgcgcaa catacgtacc cgaaccgatc tttctttcta
     4921 agattccttc atctgccaag ttttgaattg cttgtctcaa cgtcatacgg ctgacattga
     4981 atttcactgc taattctctt tctgaaggaa gacggtctcc gactttccat ataccctgtt
     5041 cgatttcatt ttttaattgg tcatgaatct gtatatatac aggtaattga ttcgacataa
     5101 cgtacacccg tcctttcgtt tcttctatta taactggtat atacctgatt cacaactgaa
     5161 aaagataaag gtttctatcc atcaacagag gatttagaca cacatcgttc tccctactcc
     5221 tattgtcaga aacaattttt tagatatgtt caacctagaa aataacaaaa gaccctaaaa
     5281 tcgatgaaaa tgccgactta tggatctttt gttattatta gcggttttta gccatccatt
     5341 tttttgtatg attcgttggg cgttttgatt ttacctggac cgcttttccg ccttttttcg
     5401 gaatattcac ttcaatattg tatttttctg atttgaccaa atcatataac ttttcagctg
     5461 cttcgtctac tttttctttc catttcatgt ggatccctcc aattcttgta gttaacttaa
     5521 ctctatctta attcagcaga atcttcaagg aacaaggtag caaagcaaaa aaaagagctc
     5581 tcgaactaac
//
LOCUS       DAPBBR010000106         5409 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPBBR010000106 DAPBBR010000000
VERSION     DAPBBR010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.112"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(153..551)
                     /locus_tag="RD488_002680"
     CDS             complement(153..551)
                     /locus_tag="RD488_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDT7658678.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="RD488_002681"
     CDS             complement(548..1321)
                     /locus_tag="RD488_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7658679.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="RD488_002682"
     CDS             complement(1318..2001)
                     /locus_tag="RD488_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7658680.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="RD488_002683"
     CDS             complement(2168..3055)
                     /locus_tag="RD488_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7658681.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="RD488_002684"
     CDS             complement(3052..3921)
                     /locus_tag="RD488_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7658682.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="RD488_002685"
     CDS             complement(4058..5344)
                     /locus_tag="RD488_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7658683.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
BASE COUNT         1660 a         1209 c          904 g         1636 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atgcaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcgtcatac
     5401 caaaatttg
//
LOCUS       DAPBBR010000107         5199 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPBBR010000107 DAPBBR010000000
VERSION     DAPBBR010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.113"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            23..694
                     /locus_tag="RD488_002686"
     CDS             23..694
                     /locus_tag="RD488_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7658684.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="RD488_002687"
     CDS             753..1193
                     /locus_tag="RD488_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658685.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="RD488_002688"
     CDS             1205..1873
                     /locus_tag="RD488_002688"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7658686.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="RD488_002689"
     CDS             1937..2560
                     /locus_tag="RD488_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HDT7658687.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="RD488_002690"
     CDS             2616..3002
                     /locus_tag="RD488_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HDT7658688.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="RD488_002691"
     CDS             3215..4606
                     /locus_tag="RD488_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDT7658689.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1727 a          861 c         1095 g         1516 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata gttcctcata
     4801 ttttacgttt ggttgagctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
     4861 aggtcgtgag cctgccgttt cactctgagt cacaaagagc aatttcaaaa aatagcttct
     4921 catgtttgtt gaatattgtg tcttgtgacc gaggagttgt caggagaaca ccgtttacca
     4981 gaggttgtga cttgttttta gtcacgacct ctttttttat ttattccata taaatacaca
     5041 ttatttattc cgaaaagtga aagcgcaaat aacaaaaaca accaacttat ttattattaa
     5101 agaaaagcgt atttaagtag gacgattctg ttgagagctt tcgtagattt tcccattttc
     5161 ctatggtaaa ctgacaaagt tgagaatgtt agaacagat
//
LOCUS       DAPBBR010000108         4912 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPBBR010000108 DAPBBR010000000
VERSION     DAPBBR010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.114"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            241..2613
                     /locus_tag="RD488_002692"
     CDS             241..2613
                     /locus_tag="RD488_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658690.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIREEIERFEKGESSFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGQSELQAGIQAVANNIGIQIRDITESEIYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKLSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVQQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2674..4134
                     /locus_tag="RD488_002693"
     CDS             2674..4134
                     /locus_tag="RD488_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDT7658691.1"
                     /translation="MTEKKMSLIDRCKQMDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEAKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLITELKPKHERQNF
                     LVRDNRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVHCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNASFDQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAILFQQGRQQERE"
     gene            4145..>4912
                     /locus_tag="RD488_002694"
     CDS             4145..>4912
                     /locus_tag="RD488_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7658692.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKTTRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYRYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADQGKTYKRLWINSLEKEAIYQGFQQLRDAGETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGISGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKAQVTAQNGTFDAKFDPNETQVTQEAFEA"
BASE COUNT         1875 a          813 c         1055 g         1169 t
ORIGIN      
        1 ctaatgagtt ggtagtgata acagtggttc gggtaacaga ctaaacaggg tagacaaacg
       61 ctacaggagg aaatagcaaa ttcccgttgg atcctttcca tacatccatt gtactctgag
      121 aaatcacaca atatcgaaac aaattccgtt aggaatgtgt tattcaataa attttataat
      181 ctagaaacat tttgaataaa aactattaga caaatgatat tttacgagga ggaaacggac
      241 atggcagaag aaaaagaacc actagacaat agtcgtttgg gaaaatccaa aagaaaatta
      301 gtacgattgc aaaatgaatt aaatgaacaa atcgaaaaga tgtttgaaca ccaaaaaatg
      361 acgaacggtc aaccaatgaa cgacaagagg aatggccgtt catggtttaa ccagcaagaa
      421 cgaatcgaaa ataaagtcca aagtctgaga gaagagatca agcaacaaga aaaacaggta
      481 gaaaaacttg aaagacaaga agagctaaag gaaatgggtt ataacaagta cggcggacta
      541 gatatgacga tcgaaaatat tccaagaatc agagaagaaa tcgaacgctt tgaaaaaggt
      601 gaatcgtctt tttcagccgc cacgatccga aaatatcaac ggaagttgga aacattagaa
      661 cagctgaaag aaaaatcaga aaaaggaaaa gaaaatatcc tccctgaagt acaagcgatc
      721 attgacagcg gacgagtaac gcaatggaaa aaaaatccga ccatttattt tctgaaaggc
      781 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      841 caagccacat cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgcgcca
      901 actgattctc tgaaggagaa agaaaacgat catttctatc gagtagaatt caacgaaaat
      961 gatccagaaa aaggattgaa aagttatggt ggagagatcg taacattaga attgatcgat
     1021 caactcaaaa cgttggacaa ccaatacgct gcagaagcag gttattataa attctatttt
     1081 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
     1141 aacagtaatc aacccatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
     1201 gaacaaaaac aaacggtcaa aaatgaacct gtttcgaaag aacaaatgca gtcgaaagaa
     1261 acaaaaacaa aacaaaaggg atatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1321 aaatcacttt cgcaacaggc actggatgcg gtgaaaaagc atacccattc tcctgaagac
     1381 gtcaaagaac ttttgaactt tatgtctcgt tttccagaac gatcctttag aaatcaatta
     1441 ttgattgagg aacaatttcc aggtgcaacg gcttgtttag gtcgtgccgc gttgaaaaaa
     1501 gaaggaatct atatcaaaaa aggggaacaa gggaacaaga tctttgtcag aaaaacggtc
     1561 aaaggatttt atgagaaagg acgtggcttt gttcgagaaa cagaagctac accagaagat
     1621 aaaaaacgaa tcgaaagtgg tcaaatcgaa gtgatcaaaa aaccttacta cacgattgaa
     1681 aaagtgtttg atatcacaca aactcagtta aaacctgaag actatccgaa aatcttcccg
     1741 aaccgtgtct ttgattttca attggatcaa acagggcagt cagaacttca agctgggatt
     1801 caagcggtag ccaacaatat cgggattcaa attcgagata ttacggagag tgaaatctat
     1861 caaagagaat taggacaagc acgtggggcg tatgttcgta acgaatttac tggcgaagaa
     1921 gaaatcgtca tgaatactcg aaatactcct acgcagcatt tagctacaag tattcatgaa
     1981 ttagcccatg caagaatgca caaactttca gaattagata ccgcaactaa agaattgcag
     2041 gcagaaatga cttcttatat tgtgtgcaaa cattttggaa tggacacgtc ggagaaagct
     2101 attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa ggaagctgcg
     2161 gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat tcaaaccatt
     2221 tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc agaagtgcag
     2281 caggagcata aaaatactgt agaaacggca gaacaaaaga atattgtgcc tgttggttca
     2341 ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg aacgttacat
     2401 ttgaaggatg cggcgtttat tgaagatccg cagcataatc aagtaatttt aaaaggaaaa
     2461 agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct aggaaatcca
     2521 ttccgatttt cacttgagac agtgtcagaa gtggccaaac gaaaaaatga aatctattat
     2581 gaacaacaat tgtcacaaaa agaacgcgta taaaacaagt aagaaagact atctgaaaaa
     2641 tggatagtct tttttctttt gggaggtttg aaaatgacag agaaaaaaat gagtctcatt
     2701 gatcgatgca agcaaatgga tattgtggat tttgcacgaa acaatggaat ggctgtagtc
     2761 aataaaggac gtgactatcg cttagaagac catgattcgt ttgttttcga tcgaagaaaa
     2821 caacgttttt attggaatag tcaaaatatt agtggcgaca ttattgaatt agctaaactt
     2881 ttttttatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc cactgatttt
     2941 attctaaaga atgaagccaa aacagaacga gtagaaaatc ttcattttga gacagaaaag
     3001 tacaaagatc accccgttga ttatcaacca cttacagaaa aaggaaggaa ttatctgaag
     3061 gaagaacgaa aattgccaga gtggctgatt gattatgcag aaaaagaagg attgattact
     3121 gaactaaagc caaaacatga acggcaaaat tttttagttc gagacaatcg tttagatcat
     3181 gcagttgcct ttttatggaa agatccacag acaaaagaga ctgtgggggc gagttatcaa
     3241 ggaacgttta ttgattatga acgttttggt gagagaggaa catataagca tatagataaa
     3301 aattcgacag cgaatcatgg ctttaaccta aagatcggtg accctaagca gttaaaattt
     3361 tttgagagta gtattgattt acttagctac gctgcactga atcgtgatca gttaaacgat
     3421 acgtggttag tctctatgga agggttaaaa caccatgtga tcagtcatta ttttggtgag
     3481 gcagtatctg aattgagaaa gaaacaagcc tttcctcaat cgattgagat ttgtgtggat
     3541 aatgatcgtg caggacatat tttctacgaa aaggaacaat taatgggcgc agtcgatcca
     3601 tttacgaatc agaaagtaca ttgtgaacga ggaatcgcta atgattggca agtgccaaaa
     3661 gaatacaaaa tcatttatga agaagtcgca aaagaagaaa aggtcacacc agaagctatt
     3721 atggccatac acaagacaga aaacaatctg caattaacga accaactggt ttccgctcac
     3781 aaagtcaatg cgtcttttga ccagcagctt tctgttaacg attcaataga agctattaat
     3841 ttgaaagata tttgtagaga agtcgcaaaa gaattaaaag gttgtgaacg cgtggatggt
     3901 acgtacgatt ttgatcgttt ttatcaagaa aaaggggata ttaatgctca gattcttttc
     3961 tcttataaag cagaacaata ctacaaaggc tataaaaatc atgaacatga atttgtacct
     4021 gaagtgaaaa aggattggaa cgatcaattg aagcatgaga tccagcaaca agaaatcaga
     4081 aagcaaaaac gtgccatatt gtttcaacaa ggcagacaac aagaaaggga gtgaaatcgt
     4141 catgatgaaa accgttattt tagcagaaaa accgtcacaa gcgaaggctt atgccgatag
     4201 cttttctaaa accacccgaa aagacgggta ttttgagatc caagatcgat tgttttcggg
     4261 agaaactgtg atcacgtatg gttttggtca tttagttgag ttagattcgc cagatatgta
     4321 cgatgaaaat tggaaacaat ggtcattaga gcatttgcct attttcccta cacattatcg
     4381 ctatcatgtt cctaaagata agaaaaaaca atttaacgta gtgaaacagc aacttcaatc
     4441 ggccgacacc attattattg cgacagatag cgatcgtgaa ggggaactga tagcttggac
     4501 gatcattcaa caagcaggtg cagaccaggg aaaaacctat aaaagacttt ggatcaactc
     4561 cttagaaaaa gaagcgattt atcagggatt ccagcagtta cgagacgctg gagagaccta
     4621 tccaaaattt gaggaagctc aagcacgtca gatcgctgat tggttgatcg gcatgaacgg
     4681 tagtccacta tatagtttac tcttgcagca aaaaggcata tcaggaagct tctccttagg
     4741 cagagttcag actccaacgc tttatatgat ttatcagttg caagaaaaga ttaggaactt
     4801 caagaaagaa ccctactttg aaggaaaagc ccaagtaacc gctcaaaatg gcacatttga
     4861 tgccaagttt gatcccaatg aaacccaagt gacgcaagaa gcatttgaag cg
//
LOCUS       DAPBBR010000109         4787 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPBBR010000109 DAPBBR010000000
VERSION     DAPBBR010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.115"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            960..1928
                     /locus_tag="RD488_002695"
     CDS             960..1928
                     /locus_tag="RD488_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7658693.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            1945..2469
                     /locus_tag="RD488_002696"
     CDS             1945..2469
                     /locus_tag="RD488_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7658694.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTETHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            2845..3126
                     /locus_tag="RD488_002697"
     CDS             2845..3126
                     /locus_tag="RD488_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658695.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            3128..3544
                     /locus_tag="RD488_002698"
     CDS             3128..3544
                     /locus_tag="RD488_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658696.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPATNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            4211..4435
                     /locus_tag="RD488_002699"
     CDS             4211..4435
                     /locus_tag="RD488_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HDT7658697.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            4455..4742
                     /locus_tag="RD488_002700"
     CDS             4455..4742
                     /locus_tag="RD488_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7658698.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
BASE COUNT         1837 a          782 c          805 g         1363 t
ORIGIN      
        1 cactttagtg agttttgtag aaagtacctt taaaggtact ttcacattac gaacgatacg
       61 tccgtaggac gtactgaaag ggtgggattt atgagcgaac taatgcaaaa tttggctagc
      121 aaaaaaagtt aaaaaatata tgctaataat cgagcgaaat gaacactttt tcaagtgagc
      181 gaatccgcca tgacaaagct gaagcagttt atttcagctt tgtcatggcg tgtgcctaga
      241 cttttaaaaa agtcggcaca cgagcaaata tctttatcaa gctctaattt gcgttttaag
      301 acgtttgaaa cgtctaagta tataaatata taagagtagg tttaagagtg cttaaatcga
      361 attttagagg gcattcagac aactttaggg ttgttagggc ttgccctgac cgcctgtaag
      421 gcgctttaag aacaagataa gggatttata ctaagactgt cttaaaacgt ctcaaacgaa
      481 ggctcatagc ttctcaaaga gttccttatg aacattttta gcaaaggagc cggaagcgac
      541 tgcgcagtat aatgtgagag cagagcgatc acaccttttt aagcgactgt agggagtaag
      601 attcccagtt gagaaaaatg cgcgaatctg tttggagaaa aaagaagtgg ttttttaggc
      661 gggaaatttt gtccccctct tttataatct ctttttaaac ctctttttaa acctctttac
      721 cgtcggctat atccttactc tcccaaggga atgacgcttt tatctacatc gttttgtctg
      781 tttatctaca tcgttttgtc tgtttatcta catcgttttg tctgtttatc tacatcgttt
      841 tgtctgtttg tacattgaat tagtacatcg acgatgttaa tataagatgt agataaacag
      901 gcattttgta tttcataacg tgtatctctt gtgcgagtaa gaaaggagct attttaaata
      961 tgtctaatga aatcgtaaag tatcatcatg aattaaatac aattccgttg cgaaaattta
     1021 caccagtcga aatgaatttg ttcttttcta tcgtatcaag aatgcgtgat gtaggtgata
     1081 aaaaagtaca atttacattc gagcaattaa aagatttaag caattataaa gcaactgcaa
     1141 atgttcgatt catagatgat ttagaaacaa cgtatgacaa attaatggat ttacgttttg
     1201 gtagaagaag tgctgacggt ttgcaacgtg aacgttttgt tttatttaat caatttaaaa
     1261 tcgacggaaa atctgatatt ccttttgctg aaatacaagt tcatgaaaaa gccttaccct
     1321 tacttaataa tcttgaagaa tgggtgcgct attctctcca acaattcaat gaattagaaa
     1381 gcagttattc aaaaacaatg tttcgattac taaaacaata cagaaccaaa ggtttcgctt
     1441 atttttcaaa agaagacttt catgaattac ttgatattcc taaaagttac aaccaaggta
     1501 cgattgatca acgtgtgttc aatccaatac gacaagaact aaccgcaatc tttaaaggtt
     1561 taacaatcaa aaagaaatac ggaaaaggac ggggaaagcc tgtcattggc tatcaattta
     1621 catttaaacc tgagataaaa aaatcagacg actttaacaa acatgcccca acaaaagaag
     1681 aacaaaacaa agcattagaa ctagctaacc aacaagttca atctgaaaaa gcacctactt
     1741 cattacaaga aaaaatcaaa gaacaaaagc gaaaattgga acttttacaa cagttagaaa
     1801 agttagaaag agaacaaaat acccaaaata aagaaaataa tgcacaaaaa tcagagataa
     1861 attccgatat tccttcagaa ctaaaaaaag acttattaga caatcttcaa aacttattca
     1921 aagattgagg ggtttttaga ttttatgaca gaaaaaacaa tcaaagaact tgctgaagaa
     1981 ttaggagtta gtaaaacagc aattaacaaa aaagtttctg acgaaaatcg aaaactttgg
     2041 ttttcgaaaa tcggaaacaa gtttgtgatt aatgaaaccg gacaaaaggc tataaaatca
     2101 atgtttttta acgaaaacga aaactcaaat caacaactag ttggcgaaaa aacgaaaacc
     2161 gaaacccaca aaaacgccaa ccaagttccc gaattagaag tcctttctct cctagaacaa
     2221 cagttaaatc aaaaagatat gcaactacaa gaaaaagacg agcaaataaa acaaatgcaa
     2281 aaattactcg accaccaaca acaactcacc ctgcaagcca accaacaaat cgagaaactg
     2341 caggaacaac tacagttgac ttatacggaa gaatcttcgg aaaataaatc aacgactctt
     2401 tctgaagaaa cagaatcgat agaaaaacaa tcaaagacgg agaaaaaatg gtggcaattc
     2461 tggcaataaa accagcaatt taaattaata aaaattgctg gttttattct tctttttgct
     2521 tttgcgagca gagcaacatg gacccatgtt gcgatatttt ggtggcgccc caatccccgt
     2581 tttttcgttg aatcttactc ggactgcact cgttttacag ctgatttttc tgaattttga
     2641 aagagcataa ggaaacgtgg tatcactttc ttacgaaagg tgctagatag gctgtgccta
     2701 tcacgtttct cagaaaaaaa tttgctatca cttttttgcc attgtggcta ggctatgtat
     2761 agtgttttgg cgaaaaatag ctatacaaat actatatttg tatgatatac ataaattata
     2821 tactgatacg aaaggaaaat ttccatggac attttagttc gaaatatcaa tcccaaaatt
     2881 attacaagaa tagataaacg ttgtcaggaa ctaacaacca aaacgggcaa aaaatggagt
     2941 cgaaatcaat acctaaaaat tttaatcgaa aacgattttg accacgaact tatgaattac
     3001 aaaaaagatc aattcgattt attattcgaa aaatttattg ccattcaagc agaaaatacg
     3061 aacatactaa atgactatgt tcacacaaac aaccaactca ttgaaacact tatcggagga
     3121 atataacatg agaaaaactt ctgttcaaaa acacgtaacc ctttatccca gtcacgttga
     3181 cgttttagat tccatcatcg aaaaaaatcc agacgtcaac aattattcag aagccattcg
     3241 ctttttatgt atgagttatg aacctgctac caatacaacc acaaccagta accaagcaaa
     3301 actcaatgcc atgggaaaag aaatttctat catgacagaa atcatggcag aatttgctga
     3361 tttatatcta aaagatactg gtgttcttat cggtacaaat tctaaagtgt atcaagaagt
     3421 gaaagaaaaa attgaaaatc aactcaatcc ttcccgacga aatcaaccca aaaatcgtca
     3481 aaaagaaacc aatcaaacct ttacttctgg aaattttgac ccaacaaact ttctaaaaag
     3541 ataaaaaaag aaaccgatcc ctaaaaaaat tcctcgattt ctttttaggg atcagtcttc
     3601 cagcaagatt tgcaagttgg taccaacttg cgaaaaaaaa gaaaaatccg cttatgcaac
     3661 ttcttctttt tgtattttgg ggcgctaccc caatccccaa gtatcggtta tttaatagcg
     3721 cggaaatcca aagaatagga cgtaccctga aacaaaaaaa gactgctctc acgagcagcc
     3781 caaaatgaga ttatcctatt catcaacata aaaatattac aaagtgaaga actagagaaa
     3841 gacaaaaaaa gcatatcaaa tcctctcaaa aataacaagt cttaaaaaaa tgacagataa
     3901 aaatgcacaa agaattagat atagataacc gcgaaaaatc aagctttaga aagttgcttt
     3961 tagctagacc aattaaaaat cacaaagtga gcgtctctat ccattggtag aggggctact
     4021 tggcatagtg tacattatgt ctactagctg tttaaataac tgatcttata attttattta
     4081 aacgattatg aattcaaaac tactttttat gacgttaatc attgttatat aataaaatgt
     4141 tatataataa aattactaag attatttaat ataacaagca attttaaaaa aacgaaaagg
     4201 aaaaacaatc atgaaaaaga aagtattaaa acattgtgtt attctaggaa tattaggaac
     4261 ttgtctagct ggcatcggta caggaataaa agttgatgca gctacttact atggaaatgg
     4321 tctttattgt aacaaagaaa aatgttgggt agattggaat caagctaaag gagaaattgg
     4381 aaaaattatt gttaatggtt gggttaatca tggtccatgg gcacctagaa ggtagtggta
     4441 gggaggttat tataatggat tttactaaag aagaaaaact tttaaatgca attagtaaag
     4501 tatacaatga agcaactata gatgactatc ctgacttaaa agaaaagctc tttctttatt
     4561 ctaaagaaat cagtgaggga aaaagtgttg gtgaagttag tatgaaatta agtagttttc
     4621 ttggaagata tattttaaaa cataaatttg gattacctaa atctttaata gaattacaag
     4681 aaattgttag taaggaatct caagtatata gaggatgggc ttctattggt atttggagtt
     4741 aattctttgg aataaaatga aaatgggact gaagaatcaa ttctgat
//
LOCUS       DAPBBR010000110         4782 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.116, whole genome shotgun sequence.
ACCESSION   DAPBBR010000110 DAPBBR010000000
VERSION     DAPBBR010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.116"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(207..1169)
                     /locus_tag="RD488_002701"
     CDS             complement(207..1169)
                     /locus_tag="RD488_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7658699.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="RD488_002702"
     CDS             complement(1171..2610)
                     /locus_tag="RD488_002702"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDT7658700.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="RD488_002703"
     CDS             2795..4741
                     /locus_tag="RD488_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HDT7658701.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1521 a          820 c          789 g         1652 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa at
//
LOCUS       DAPBBR010000111         4177 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPBBR010000111 DAPBBR010000000
VERSION     DAPBBR010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.117"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(51..1199)
                     /gene="nagA"
                     /locus_tag="RD488_002704"
     CDS             complement(51..1199)
                     /gene="nagA"
                     /locus_tag="RD488_002704"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDT7658702.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1275..2111)
                     /locus_tag="RD488_002705"
     CDS             complement(1275..2111)
                     /locus_tag="RD488_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658703.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2295..3512)
                     /locus_tag="RD488_002706"
     CDS             complement(2295..3512)
                     /locus_tag="RD488_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7658704.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3661..3840)
                     /locus_tag="RD488_002707"
     CDS             complement(3661..3840)
                     /locus_tag="RD488_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658705.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3895..3978
                     /locus_tag="RD488_002708"
     tRNA            3895..3978
                     /locus_tag="RD488_002708"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3929..3931,aa:Leu,seq:gag)
BASE COUNT         1216 a          890 c          694 g         1377 t
ORIGIN      
        1 ccttaaaacc aaacttaaga agtttagttt taaggttaac ttaaattata ttatgcgtgg
       61 aaacgttcca cgccatctag ataagttgct tccaatgtca tatcagggtt caatacgata
      121 aagtctgcat cgcgtccttg agcgattttt ccacatgtat catcgatttt acagctgatt
      181 gctggaatca gactagccat catgactgct tgttctggtg ttgctaatcc ccagtctaca
      241 acatttttaa ttgcttcttt caatttcaat atacttccag ctaagttgcc agattctaga
      301 cgtgctgttc cttcttttac tactactgga aattcgccta aattgtaatt tccatcaggc
      361 atcccaccgg ccatcataca gtctgtaatt aatgcgacat gatcatgtcc tgctttttcc
      421 attaggattc ccgcagcatt tggatgtaca tgatggccat cacaaatcaa ttcagaaaag
      481 acatgttcta aagataataa cgcacccacc atacctggtt cgcgatgatt caatccacgc
      541 ataccattga aagcatggac aaatacactt gcgcctgctt caacagcttt ttgcgcttct
      601 tctagtgtag cattactgtg tcctagagaa acaactactc cttcttcagt cacttgtttg
      661 acaaactctt ctacaccttg acgttccggt gctaaagcaa tttttttgat taaaccacct
      721 gaagcttctt gccattcatg gaaagtatcc aaatcaggat ccccgaaata acttgggttt
      781 tgtgcccctt tgtgttcttc tgtgaagaaa ggaccttcaa aatagattcc tttgatttta
      841 gctcctggtg cttcctgata cattttgccg attgtctcag ctacatcttt taaacgttct
      901 ttgcttgacg tcaatgttgt tggtaaaaat gaagtcactc cacaagataa cagaccttca
      961 gacatcactt tgatgccttc tgcatcatta tccattacat catgattcat atagccgtga
     1021 atatgtgtat ctaccaaacc aggagcaatc catttgccgc tttggtcaat gatgttgact
     1081 tctccctcag gtagttcttt ggtgtattca ccaaaaagtc catcggtaat ttcaagatag
     1141 cctgcatgtt tgacacctga cgctaaaaag aatttgtcag catagataaa agttctcatt
     1201 ctattctctc cctttgtttt tctacctcta aagtactctt atttagagaa gaagtcaaga
     1261 atggtctaca ccatttacaa attttttgaa atttgtttca cagcttgtgc taagccttca
     1321 tagaatgctg ctctttctgg ttcttcttta cgcttgtata ttaagctttt aagcacaaat
     1381 aaatcattga ggtaatagta gctattcttc tcttgagccc aatagattcc ttgattcacc
     1441 tgttctaacg cttcgtcgat ttcattttga tggaataaga aatttccata attataaaaa
     1501 atttgcgaaa attcactttt tgatcgttca tcagctgatt gatgcagcag ttggatgctt
     1561 cgactcaaat agtagcgtgc ttcagccgtt tttcctgcca caccatatat ttttccgata
     1621 caactaatca gttgtatttc tgtgtcagaa acatggattc tttctttttg gctagagtag
     1681 cttaatgctt ctttcaaata ataaagggac tgagagatat tttgacgcaa cgtgaattcg
     1741 caaacaccga gataataata atagcgttga aagtcagttg cttgatacag attttcagaa
     1801 atatcagaag attttagtac ttgttctaac ttccgataat cacgtttttg gaaacaacta
     1861 tccaacagtt caaataattt atcgtttgtc cgagtagttt ttcgagagag attcatcaca
     1921 tgatcaatcg ttacccctag ccgttgacaa atctgcatca tcaccaatac attcggcagt
     1981 tcctcattat tttcgatccg acttaataca ctttgtgaac aaatatcatg cgaaagcatt
     2041 ttttgcgtca ttttttgttc ttttcgaatc tctttaatga tcgttccaaa ggactcgatt
     2101 aacgtttcca taagtatcct ccccaaaata tgcgtattcg cattctattc gtattttact
     2161 ttaggaagtc gcaaacttca agaaaagact tgcaactaaa taatatactt tagttattta
     2221 agaaaactcc actagaaaga gagcctcagt gtgtttgtct gtggccctcc tactgaaaaa
     2281 tttggttttt aaaatcattt ttggcgatag gttgctagga attctctcat tttcttagct
     2341 gtttgtttca aatcatccat tttaggaaga taaacgattc gaaaatgatc tggctggttc
     2401 caattaaatc caccaccatg tacaagtaga atatgatgtt catgtaaaaa gtccaaaacg
     2461 aatttttcat catccaaaat attgaatcgc tttgtatcaa tttttgggaa tatataaaaa
     2521 gcagcttttg gttttacggc tgaaagacca ggaatatcat tgattgcatt atagatatat
     2581 tctctttgtt catagatcct tccgcctggc aggagcagct catcgacact ttgataaccg
     2641 cctagcgcgg tttggataat ttgctgagac aatacattgg aacacaaacg catggaggac
     2701 aacatattca gcccttctat atagcctttg acgtgtgact tatctccact taggaccatc
     2761 cagcctactc gaaatcctgc tacacgatga gatttggata gaccgttcag cgtaacaacg
     2821 aacaaatcag gcgctaatgt agcaatcgga atatgttcta gaccatccat cactaagcga
     2881 tcatagattt cgtcggaata aataatcagg ttattttgtc gagctacttc aacgatttct
     2941 tctaataatt cttttggata aagtgcccca gtaggattat taggattaat gataacaata
     3001 gcttttgtcc gactcgttat ttttgatttg atatcatcaa tatcaggata ccattctgcc
     3061 tcttcatcgc aaatataatg aacaggtgtg cctccagcta atgcaataga agccgtccac
     3121 aacggatagt ccggcattgg aaccagtact tcatctccat tgtccagcaa cccctgcata
     3181 cacatcgtga tcaattcgct cactccgttg ccggtgtaga tatcattgat cgtcacattc
     3241 ggaaaatgtt tcagttggca atattgctca attgcttttc tagcagaaaa gatccccttg
     3301 gaatctgagt agccttctga gtcacgggca ttcatgatca aatcacgaat gacttcgttt
     3361 ggtgcttcaa atccaaaagg tgcgggattt cccgtgttca attttaaaat actaatgccc
     3421 tcttcttgca tccgctccgc ttcttctaga acgggaccgc gaacatcgta actgacacct
     3481 tctaatttgt tggatttttc aaattctctc atcacttagc caatccctca tttcaaaaag
     3541 ttagaacttt ccaaattttt tgttatttac tatttcaata tcatactcca tcctagaaaa
     3601 ttttgccact tatttaggaa aaacgtaagt attaaaaaaa cacaaacaag cgttgagaac
     3661 ttaattgtca tgatagtcat tccatagatt cgctgcccaa tccattgcaa ttccacaaat
     3721 gattcctagc ataaaaccaa gcaaaaaacg tccgaatgca agtccaatca atacacctaa
     3781 gatcattccc agtcctgaaa attctccgtc atatttctcc atcttaataa gtcctcccat
     3841 ttttgagctt gacaactatg taaaacctcg ctatcattag tgtgttatta ttacgcagat
     3901 gtgttggaat tggcagacaa gcatgattga gggtcatgtg agcgttagct cgtgtgggtt
     3961 cgagtcccat catctgcact acaactcgtg aagttaattt tgcttcacga gtttttttgt
     4021 ttgaacgttt ctttatgcca ttatatacat atcactgtat cctttacaaa aagaacgtac
     4081 aatcatgtaa acagcctgag gtgagtatat gaaggtcgga aacaagctac tcgtagaaac
     4141 ttgcaagtgt taaaacaatt aatcgaaaaa cgagtaa
//
LOCUS       DAPBBR010000112         3879 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPBBR010000112 DAPBBR010000000
VERSION     DAPBBR010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.120"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..85)
                     /locus_tag="RD488_002709"
     CDS             complement(<1..85)
                     /locus_tag="RD488_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658706.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
     gene            155..316
                     /locus_tag="RD488_002710"
     CDS             155..316
                     /locus_tag="RD488_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDT7658707.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="RD488_002711"
     CDS             335..1612
                     /locus_tag="RD488_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658708.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="RD488_002712"
     CDS             1622..2278
                     /locus_tag="RD488_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658709.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="RD488_002713"
     CDS             2278..3654
                     /locus_tag="RD488_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658710.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
BASE COUNT         1547 a          413 c          676 g         1243 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagaaag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaacta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa acaattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt tgggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg gagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgtt
//
LOCUS       DAPBBR010000113         3407 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPBBR010000113 DAPBBR010000000
VERSION     DAPBBR010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.121"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..292)
                     /locus_tag="RD488_002714"
     CDS             complement(<1..292)
                     /locus_tag="RD488_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY"
                     /protein_id="HDT7658711.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS"
     gene            complement(548..1156)
                     /locus_tag="RD488_002715"
     CDS             complement(548..1156)
                     /locus_tag="RD488_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7658712.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(1162..2193)
                     /gene="vanA"
                     /locus_tag="RD488_002716"
     CDS             complement(1162..2193)
                     /gene="vanA"
                     /locus_tag="RD488_002716"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7658713.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(2186..3154)
                     /locus_tag="RD488_002717"
     CDS             complement(2186..3154)
                     /locus_tag="RD488_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7658714.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT          931 a          803 c          629 g         1044 t
ORIGIN      
        1 tactatcaag caacccgtat ccatttatta attcgtcatg tttagataaa ttcacgatat
       61 ctgacttcac actttcttgg cgaacaggat atttactatt gattaatagc agatttcctt
      121 gataaacctg ttcttctgta attgttttct cttgggtatt ttcagaagtc ccactatttt
      181 ctaaatgttc tttgggattt tgatcataat tttgaaattc gactttttcc tgagaaaaca
      241 gtgcttcatt aacgtagtca taacctaagt atattaagaa taacaataac aataaaaaaa
      301 aacaacttct tcattttcag tctcctcctt aactatatag ttggaagtat gaaatatttc
      361 tagaatcttc cccttaaacg gcacaatctc gtttgagatt gtgccgtttt gccccgtaga
      421 aggcactctc ttcgggtttt cggtctgtac tgaaatcaag gtattattgg gaatcccagc
      481 ttaaatcata gataccgtaa gggattttat tctttattta aaactttgca acagaaccgt
      541 taaaagttta tttaacgggg aaatcaaaat agctattggg gtatggttcg tctcttaata
      601 catagtgcca ccattcgagg ctatatgctt caaacccact gttttccatg atggagcgca
      661 aacgtctgcg attttgcgct tcattgcatg atattccatt tgccgcatga tgagagcgtt
      721 catccataaa atcaaatcgg ctccccattg gtacaagctc acccgtgtct aatcgataaa
      781 gcgtaagatc aatggcactg ccgcggctat ggcttgattt tgaagccacg tatccttttg
      841 aaatcatctc agttcggtca atattgggat aataactttc ctttgtcagg ttattttccg
      901 gctgtgcagc ccattgcata aaacagttta cagcacgctt aggacggtaa ccgtcccata
      961 gaagcaatcc gtacccttgg gtagcagcca gttcttttgc cttcaaaagc gattcagcca
     1021 actcgtatgt ccctacaatg cgatttactt cataaccgtc aaccggtttt ccggtgaaat
     1081 tatcccaagt ggcatattta gcgtcccaac gaacaccgtg tactatttca tctaaaaaag
     1141 taaatcctat ttccatgctt atcacccctt taacgctaat acgatcaagc ggtcaatcag
     1201 ttcgggaagt gcaatacctg cagcggccat catacgggga taacgactgt atgacgtgaa
     1261 accgggcaga gtattgactt cgttcagtac aatgcggccg ttatcttgta aaaacatatc
     1321 cacacgggct agacctctac agccgagcgc tttatatatt ttttttgccg tttcctgtat
     1381 ccgtcctcgc tcctctgctg aaaggtctgc gggaacggtt ataactgcgt tttcagagcc
     1441 tttttccggc tcgacttcct gatgaatacg aaagattccg tactgcagcc tgatttggtc
     1501 cacctcgcca acaactaacg cggcactgtt tcccaatacc gcacaaccga cctcacagcc
     1561 cgaaacagcc tgctcaatta agattttgct gtcatattgt cttgccgatt caattgcgta
     1621 gtccaattcg tccgcgctat tgactttttt cacaccgaag gatgagcctg aacgcgccgg
     1681 cttaacaaaa acaggatagg taaacgtagc tgccaccggc ctatcatctt tattaataac
     1741 ccaaaaggcg ggagtagcta tcccagcatt tttcgcaacg atgtatgtca acgatttgtc
     1801 catacaaatt gctgagcttt gaatatcgca gcctacaaaa gggataccgg acaattcaaa
     1861 cagaccttgt atggatccat cttcacctga cttgccatgc aaagctgaaa atgctacatc
     1921 aacatggttg atttcatatt catggttctt tttaacaagt aatccgtgca tttttttatc
     1981 cggcgagagt acagctgaat agcaattgtc gttttcccat tccgcgcaag gtttttcgca
     2041 cattttccat acaccagatt tcgtaattcc aatgtataac ggctcgtatt tttctttatt
     2101 aatgttagcg gctatctcta ttgcagattt taccgatacg tcatgctcct ctgagcaacc
     2161 cccaaacagt attgcaactt ttattctatt catgctcctg tctcctttca aaatccaaac
     2221 agtttttaat ggttttttca acggtatcac gcaacgcttg ctcggtataa taggccgtat
     2281 gcggtgtgat tatcacgtta ggcattcttt gaagtttaag taaaaattga ttatcaattg
     2341 gtttttgggt gcaatcagag tagaaaaact cttcctctcc ttccaataca tccaatgcgg
     2401 caccgcccag tttcccgttt tctaatgctt taaccaactc ataggtatct acaagtggac
     2461 cgcgcccagt attgataaga aatgctcctt gcttcattct ctgtatttgt tcgtggctga
     2521 taatatagtg cgtatccgta ttgagcggca catgaagcgt aacgatatcg ctattttgca
     2581 gcaactcatc aaacggtaca tagtttacct ctatacttcg gctgcgacta taagccaaca
     2641 ctttacatcc aaatcctcgc agccgctcaa taaccgcttt gcctatctgg cccgttccca
     2701 ccacaccaac tgtcatgtcg ctgagtacct tgccacggtc gctgtccaac ctgaaatcat
     2761 gtttttccac agagcgcaca atcgatttta cgttgcgtac tgccataaga attagcatca
     2821 tagtataatc ggcaacgcta tccggcgagt acgccacatt gtcgacagtg atgcccattc
     2881 tcttagcagc agttgtatct atatgattgc agccgatgct tcgggtagaa atatatttca
     2941 caccggctct cttcagcgca agaagaatag aggcggaaat ctctgattta tgtcccacac
     3001 tgatacattg attgaaaggc gcggatttgg cgttggattc cgacacgttg gcgttaatta
     3061 tcgttgccat aacgccaaag cgaggcgaaa gagcatggaa tgcatctgcc tcatcctgct
     3121 cacatccata aacagtaatg ccgatgttat tcataattaa gaccaaccct ttctgtgaaa
     3181 ggcaccaaat aaaacgggga tgccaatggt aatcttgtca aatctttctc tgaagaacga
     3241 aaacggctcg ttcttacggt attaagtcta ccgtgtaaga acgagccgtt tcttaatatt
     3301 aaattgttaa tttcctaaga aaaagtaaag ataaccttga gattttccta aaaaattata
     3361 tacatctctt aggacctcct tttatcaacc aagtctggca tcgctgg
//
LOCUS       DAPBBR010000114         3380 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPBBR010000114 DAPBBR010000000
VERSION     DAPBBR010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.122"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            179..1285
                     /locus_tag="RD488_002718"
     CDS             179..1285
                     /locus_tag="RD488_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7658715.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            1302..2326
                     /locus_tag="RD488_002719"
                     /pseudo
     CDS             1302..2326
                     /locus_tag="RD488_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            2332..2811
                     /locus_tag="RD488_002720"
     CDS             2332..2811
                     /locus_tag="RD488_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDT7658716.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            2827..>3380
                     /locus_tag="RD488_002721"
     CDS             2827..>3380
                     /locus_tag="RD488_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HDT7658717.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
BASE COUNT         1028 a          566 c          785 g         1001 t
ORIGIN      
        1 gaaaacgttg tttctccaag ttcttttttt aatttccaag taactgaaag ttacttttgt
       61 tatttaacat ttaggtcaat tttagacagt ttttgttcaa aaagcgatat ttatagtgga
      121 cggtattact gctatattaa ggatataaaa tgaaagcgtt taaaaaggtg gcgtaaagat
      181 gattattaaa gaagagattt ttgtacctaa agaattagtg aaagaaaaaa ttgacctgct
      241 cgttgaaaac ctgacaacga tcaaagacga taatggtgaa tttttgttgg actttgatgg
      301 actgaaagta gatgacaaaa gctggacagt gtggaattgg ccacaaggtg tcggtctata
      361 tggtatttat aaaaattacc agatgacaaa aaatcctcgc gcttatcaag tggtcaatga
      421 atggtttgag gatcgtatgg aagaaggcgc tccgcccaaa aacgtcaata caatggcacc
      481 gctattgact atggcttact tgtatgaaga cacgaaagat tcacgctatt tgccttattt
      541 agaacaatgg gcagaatggg tcatgaatga catgcctcgg acaaatgaag acgggttaca
      601 gcatgccaca tatggaccgg aaaataagaa tcagttgtgg gacgatacat tgatgatgac
      661 agtgcttcct ttggcaaaaa tcgggaaact gttgaatcgc ccagaatatt tagaagaagc
      721 tcgttaccag tttatgatcc atatcaaata cttgatggat aaacgaacag gattgtggta
      781 tcacggctgg acgtttgaag gaaatcataa ctatgccgaa gcattttggg ctcgtggaaa
      841 ctgctggttg acgattgcta ttccagagat cattgaaatc ttagaattat cgaaagaaga
      901 tgcattgcgc aaattattga tcgaaacact tgaagcacaa gtgcgtgcat taaaaactta
      961 tcagtctgaa agcggtttat ggcatacgtt gttggatgat ccttcttctt acgtagaatc
     1021 ttctgcaact gcaggatttg cttacggtat tttgaaagcg gtccataaac gttatttacc
     1081 acaagaatat aaagaagtcg cttatcgtgc tatccaagga ttgcttgaac aaatcgatga
     1141 aaaaggagaa gttcaaaacg tttcaatcgg gacaggaatg ggggacagtt tagattttta
     1201 tcggaatatc ggaatcacag caatgcctta tggacagtcg ttaacggtgc tttgtttgac
     1261 agaattgctc gtctcttatt gttaaaagaa aggaaaccca tatgaaaaaa acatcactgc
     1321 tgtttgcagc aagttcgctt agcctaggtc tgctaggtct aagcggctgc ggaaataatt
     1381 ctagtgtggc aactgtcgca gatgcagacg taaatgagat agttaccttg cgctttgctt
     1441 atgcaagcaa cagccagtaa ttgatgcaat gaatgaattt gggcgtttag taaaagaaaa
     1501 aacagatggt tccgtacaga tccagtattt cccagatgga caactgggtg gagaacgtga
     1561 actgatcgaa ttgacacagt caggagcagt agatttcaca aaagtaagtg cctcagcgtt
     1621 ggaaagtttc tctaaagatt attcgatttt ttccgttcct tatctattca atgatgaaga
     1681 acatttcttt aaggtgatgg ataatgaaga aataatggag ccaatctacc aatcgaccaa
     1741 aaatttagga tttaccggat tgacctatta tgattctggt cagcgcagct tttatatggt
     1801 agacggtccg atccatacgc cggaagattt gaagggaaag aagatccgtg tgatgcaaag
     1861 cgaaaccgct atcaaaatgg tagagctttt aggcggttcg cccgtaccta tgggaagtga
     1921 tgaagtgtac acgtctcttc aatccaattt gatcaacgga tcagaaaaca atgaatttgt
     1981 cttgtataca gctggacatg gcggggtagc taaatactat tcctatgatg agcatacacg
     2041 tgtgccagat atcatcatca tgaatgatgc catcaaagaa cagctaactg atgaacagga
     2101 aaaagccatt gaagaagcag cgaaagaatc aacggttttt gaaattgaag cttttgcaaa
     2161 agcaattgaa gaagaaaaag ctttagcaca agaagaacat ggagtccaat tcaatgatgt
     2221 agataataca ccgtttcgag aggcagttgc cccacttcat gatatattca aaaacgatcc
     2281 tacctacaaa gacctttatc aaaagatcca agagcaagga gcgtagctgt aatgaaaatg
     2341 attttaaaca aggtattaga gatcctggga gctgttttgc ttgttgggat ggtcgctgtt
     2401 gttttatggc aagtattttc cagaacggtt ttaggaaatc caaatacggt cacggaagag
     2461 cttgttcgat tcggtcttgt ctggtttgcc atgttgtctt ccgcgtatgt tgtgggacaa
     2521 aaagcacgtt tagccgtaac ggttttaagt gaaaaattaa ctggcaaaaa aagtaaaatt
     2581 ttagaagttg ttgttcaaag tttatttctg gtatttgctg cgatgatcat ggtgtatggc
     2641 ggatggaatg ctgtcacatt gacaatgggg cagatctcgc cttctttaag tattcctatg
     2701 ggatatgttt atctgtcagt acctgtatcg ggggtactca tcattatcta tagcctgatc
     2761 aatctaatcg atacattaag caacaagcca gcaattcaag aaaaaatata aaaatggagg
     2821 aataaaatgg caatagaagc cggattagtg ttattttttg tatttgttgt gttgcttgta
     2881 ttagggatgc cgattgctat aagtattgca ttctcatcga tgatgacttt attgttagtt
     2941 ataccgtttg atgtttctgc ttttagttca gctcaaaaaa tggtgggaag tatcaatagt
     3001 ttttcgctga tcgctattcc gtttttcgtt ctctcgggca ttatcatgaa taatggaggg
     3061 atagctaaga aactagtgga ttttgcgatg ttgttcgtcg ggcgcgtgcc gggggctttg
     3121 gctcatacga atgtgttagg gaatgcttta tttggttcca tctctagctc ggccattgcc
     3181 gcttctaccg cgattggtgg agtgttgatc cctcagcaag tggaagaagg atatgaccgg
     3241 aagtttgcga cagcggtcaa tatcgcgtca gctccgacag gtatggtcat tcctccaagt
     3301 actgctttta tcatgtattc acttgttgct ggtggtgctt cgatctctgc tttgtttatg
     3361 ggaggttatc tcgtaggcgc
//
LOCUS       DAPBBR010000115         3338 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPBBR010000115 DAPBBR010000000
VERSION     DAPBBR010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.123"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(50..1849)
                     /locus_tag="RD488_002722"
     CDS             complement(50..1849)
                     /locus_tag="RD488_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDT7658718.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            1972..2478
                     /locus_tag="RD488_002723"
     CDS             1972..2478
                     /locus_tag="RD488_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7658719.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            2557..3279
                     /locus_tag="RD488_002724"
     CDS             2557..3279
                     /locus_tag="RD488_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7658720.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
BASE COUNT          996 a          602 c          698 g         1042 t
ORIGIN      
        1 agttagccca ttctggacta actctttttt tattgtgata aaatagaaat cagataaatt
       61 cttctgtcaa ttccatgaac gtttggatat cttcagtcac catgtcgata cctgcttgcc
      121 aaaaatctgg ttgggtaaga tcgacattca aatgtttctt cgcaagatct tccgtcgtca
      181 ttgaggcagt atcgcgtagt aaatggatat attcttcttc aaaatttgct cccttttggt
      241 tggcgtaagc atagatgccc aaactaaaga ggtagccaaa tgtgtatggg aagttataaa
      301 acggtacgtc atcaataaag aaatgcaatt ttgcagccca gaaatatgga tggtaagtag
      361 ctaaagctcc ttgatagcct tctttttgcg cctcaaccat catctctgtg atcttatctt
      421 ctgagactaa tccttcttgc cgtgcttcat agaatcgatt ttcaaaaatg aatcgggaat
      481 ggatattcat gaacatagct aaagcatttt gcagttttgt atctagcaaa ttgatttttt
      541 cttcttttgt ttttgcgact tttaatgtag catcggctac gatcagttct gcgaatgtac
      601 ttgctgtttc tgcgacattc atggcatatt cgcgatttaa agaaggtaaa tcccacatcg
      661 tgctgctatg gaaagcatgt cctagttcat gagcaagtgt cgcaacctca ttaacagaat
      721 tactgtaggt cataaagatc cttgattctt ttgtttctgg taactcagta caataaccac
      781 caggacgttt cccaggacga tcttctgctt cgatccagct cttttcaaaa gcagattggg
      841 caaatttagc catttttgga ctgaatttgt taaagttttc gataataaat gctgctgctt
      901 cgtcaaaact aaaggttttt tctttcaaat cgcctaaaat aataggtgca tcttgatctt
      961 gccattccat tttttcttta ccgaaaagat tagcttttct agtcaagtaa ttaacaaggg
     1021 gttgtttgtt tttctggatt gtatcccaca tgacagacaa tgtttctttc ttcaaccgat
     1081 tgtactctaa tggtttttgt agaaaatctg tgacaccatg aagttcatag tcagaaagtc
     1141 taaaaccatc taaatgattc aaagtatccg tgaagagggg tgccttttct ttccaggctt
     1201 cttcccatgc tgcgaaaagt gtttctctga cttttggatc tggatcgccc atcatcttat
     1261 tgaaggcttg tccagcagat aattcgacta cttgtccatc ttgttcgaag ggaatcgaaa
     1321 tgctggctac aatcgtatca taatgactgc tccaagcatt tagaccatct aaagaaagcg
     1381 tatttataat gttttcttca gcttctgata ataattgtga gccatcacga cgaatctcgt
     1441 ttaaacgaaa agcaattgtt tcaaacgaag attgagaaag catctgattc caatcattgt
     1501 cagatatttc tgcaaatttc tttgacaata cagtttcggc tgattgcaga cgaggcagca
     1561 ttgcgtaaag cttgcctgat aagacctttg catctgaatc attgacattg gcagaaagca
     1621 atgcagtaat atagctgctg cattgggtaa aaccattcgt aatcgtttct tgcaattgaa
     1681 gaatagcgtt taactgctct gcattgtcag aactaggtga ccattttgtt acgcggtgat
     1741 aatactcgtt catttggtct tccaattgct tcatccgttg gttcaaagca tcagaatgac
     1801 tgcctccgga aaaaatagaa tctagattcc aatttaatga ataactcatg aaaaaactcc
     1861 cttcatattg taatacaaaa ttaagtatag cactttttta tggaagaagt ctctatgaaa
     1921 atgattgttg tttcttcaaa aaaagtctaa gataaaatac agaggtgact tatgaattct
     1981 tcaaaaaaac aaatgaaaaa cggaaatatt tatttagtaa tcgcactgat agtcgttata
     2041 atcttatttt acagttcttc tcaaacttac ggacagcaat cacaagtttc gcgattagaa
     2101 agctggctgc ctaatcagcc atttaaagac acattagcgg gtatacgttt taattatggt
     2161 ggaagtatgg tgagtatcga ccatctgggc tacgccaaat ttttagagtt ctttttaagg
     2221 aagggcgcac atttcggtac ctattttatt ttgggaggca gcttgttttt aggtgttttc
     2281 cccaagctaa aaatttggtg gctgacagcg atccttgctt ggctttcagc aacagggtac
     2341 gcaggtttgg acgaattcca tcagatgatg accggtggac gaacacctat gttccaagat
     2401 gtcatgttgg attcgatcgg tgctctgact gctgtgatat tatgtgtgct ttttgcggca
     2461 ttcaagaagc gtttatagat tggctgtggc tttgtttttt tgtgaaatag tactagaata
     2521 gaagtgtatt ctcaaaagaa caagggagga aaaatcatgt caggacatag taaatggcat
     2581 aatatccaag gaagaaaaaa tgcccaagat gcaaaacgag ggaaagtctt tcagaaactt
     2641 tctcgtgaaa tttatatggc agctaaagca ggcggtcctg atccatctat gaatccagct
     2701 ttgcggcttg ttgtggacaa agcaaaagct gcaaatatgc ctaacgacaa tgtggaacgg
     2761 gcgattaaaa aggctacgag tgccgtagat gaaacgaatt acgatgaaat cacgtatgaa
     2821 ggatatggtc cgggtggagt aggaatctta gtccatgcat tgacagataa ccgtaatcgg
     2881 acagcgacaa atgtccgagt agcttttact cgaaacggtg gatcactggg agaaacgggt
     2941 tcagtcagtt acttgtttga ccgcaaagga tatatcgcta ttgaacgcga tgggttgact
     3001 gttgatgaag agacgatgtt tgaggatgta ttagaggcgg gggcagaaga tctgcaaact
     3061 tctcctgaag tattcgagat ttatactgca ccagaagatt ttgctgctgt acgagatgag
     3121 ttggaaaaag agttcacttt ggcgcaagca gaattgacga tgattccaca aacgacgatt
     3181 gatttaaatg aggaacaaaa agagcaattg gaacgtctag tagataagct agaagacgat
     3241 gatgatgttt cagaagtctt tactgctgct gaaatgtaag tagcacattg ttagataata
     3301 aaaagaaagc acctgtacca atcgtacggg tgctttct
//
LOCUS       DAPBBR010000116         3205 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPBBR010000116 DAPBBR010000000
VERSION     DAPBBR010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.124"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1646..2164)
                     /locus_tag="RD488_002725"
     CDS             complement(1646..2164)
                     /locus_tag="RD488_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HDT7658721.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1079 a          568 c          454 g         1104 t
ORIGIN      
        1 ataaagaaaa aattcaagca acaattcaaa aaaatcttaa ctgctgagat tgatgtagca
       61 atatctcaat catcaacaaa gtacgatcct gcctttcaaa agcttattga taaatgttta
      121 ttcattataa aaataaaaga aaaatttatg tcagcttttt tcatcaaagt ggtaatgata
      181 attcgtctat taattgtatt ttttaggaaa tatggtataa ttgttttaac gaaaaggtaa
      241 ttcatgatac accaaaaacc actagctggc gggctagtgg ttttctttta cgttctattc
      301 agattaacgg gtaggcttac tgtctttttt ggcaataatt ttgcaatcaa gccatttaca
      361 gatgtaatgc gcggatactt ctgctaagat tgcaaaaaac atatcgaaaa ggtaattcat
      421 aatacaacct cctccccttg ccataatagg ccggggtagc agacagcata aatattatac
      481 cataactgaa aatttcattt tagtacattt caatatattg atgaaccagc acaataaaac
      541 atgccatgac taacagaaaa aaacttatta aaccagatat aacttgtaaa catccaacta
      601 tatagaaaac gtaaattttc tatatagttg gattaagata acgactattt attttatcat
      661 atttttacta taccctatac ttttacttgg tatatttatg aataatcgca aatttacccc
      721 tatactacta gtttgtaagt tagattaata aaaatactaa agttatttgt tcttttatta
      781 aatacaccta caacttataa attgatggta tttagataac acgaaagaat aaaaataaca
      841 gctgatagta aagtttgttg acgattgcta ctcaatcgaa agtgagttag tgcgtatgaa
      901 cttgcttctg aaaacttatg aaatgaaaga ccttttacat cttgcagaaa tcgttactgg
      961 gattaaacta agcaataaaa actaatgttc ccctcattct ttgaacttct actatttgat
     1021 ttatttattc tgataaatga cgatttcacc ttcaggatct tcaaatcccg tatagaattt
     1081 atttaagatc tcttcagtat cagtaatagg ataggcgata ggccacatac cctttgatgg
     1141 ttagaataaa ctgctcaaaa tctgtatcgt atgttggctt tagcatatta acaaaggcta
     1201 tctccaaatt ataaaccata agcgttgaat cgttcttaac aatttcaatt cttcctaacc
     1261 caaagtcaga agatataatt accggacttg ccttaccctt catgtgggtt gttgagattc
     1321 catatttaaa gggaattgtc ggtactatcg gcggtctgaa aaacatccca aaaataaaaa
     1381 aatctttccc ctgctagtct cctaagtccc tttgtagcgg atatggcacc ataatctcat
     1441 tttatcgaag tgagtcatgg tttatctgtt ggccaaccaa aattgataca atctaacgat
     1501 gcaccctcta cggcattcta ggggagtgca cttgcattca cccaataaaa accggcagtt
     1561 agcaaagaac ttatgtagtc gtatgttctt actgttaaca tacaagaggt ctcctttcca
     1621 caattgctta gcagtaaacg ggaatttaca aagctaatct cttccatttt cttatctttg
     1681 ttctaaaagt cccaaatgga gcaactgtat ttacatgaat aaatttatat acttcccata
     1741 cagccgtttt ggttgcctcg tctgcccatt ttcttttgtg tgcagtgaat agatcttcat
     1801 cactcattga atcaatcatc atgttaatat catcaatatt acgattgaga atttcctcta
     1861 attctttcaa tggtagatgt gcataggtat ttgtaaacca cttatataac tctcctaact
     1921 gattccattt aaattgatca gaaggcgttt taacagataa tccatttctt tcatcatttt
     1981 cccattttag aattaaattc gtccaaccaa cttgatatgc taaattttca gcaggtgttc
     2041 tatccacttc ctcaactctt ttatccttca attcttcagg aatagtttca aattctaaaa
     2101 tatatttagt ataagtccta tttatttctt tttttaattc ttctttattt ttatatgttc
     2161 tcattatatt acctccataa attcctaatt gtctccttta attcatctat aatttcatcc
     2221 acgatatttt aatccgttct acaatgcata tctgatatgc attgactgtc taactcatat
     2281 gtgaatgatt tataaaatat cccaacgtct catctaaaga aatgttgatc gtcagcaagg
     2341 agctaaaaaa tacgaatata tttcttttgt agtaaaatcg gactggtttg catatcattt
     2401 tcttcgtaaa tatcaaaatc atgttaacta ctatcaatta ctaataaaaa ctaccacttt
     2461 aagcgttaag aactgttaag tttagttaag tgaggatagt tcacaaaatc cattgttaaa
     2521 cttcacgaaa gtggtaaaac tcaaaatgct ttatatagga ttacagcatc gctctttctt
     2581 cgattgcgcg ttgggtaaaa aatattatga agtaaaaatt gacgatgaca cgttccttac
     2641 ggctcatcag atgaaacagc tacaaaaacg aaatgatcaa ctcgaagaaa atttaattct
     2701 aaaaaagcga ttgccatatt cacgcctcgc tcgacgaact attaaaggtc aagatttacc
     2761 tgaagatcat cctttttagg aaattgaagc tttttatgtt gcacaatgca tttataatac
     2821 tacaatgatg ttttcaccag atattcttct agggtgcggt gtaatgaaac agatacactt
     2881 gcaaaagaaa attcaccgcg aatttactaa aattatgaat aattatgtta atcttccgaa
     2941 atttttttcc aaaattaagg gatcaagctg gtgttataga ttgtttaagg ttggcaaaaa
     3001 aataacttct ttttaaacaa ttatagaaaa ccgatactct gttaagttgg ttgacacggt
     3061 gtcgattttt atgactttct tattctgaaa cttcactaac ggacagtacc taaaaagtct
     3121 atagtatgga cgtttacgag tactatttta tcaaaaatgc tgctcatttc aacttatatg
     3181 ttttagtgaa ctacccccac ttagc
//
LOCUS       DAPBBR010000117         3140 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPBBR010000117 DAPBBR010000000
VERSION     DAPBBR010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.125"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(14..676)
                     /locus_tag="RD488_002726"
     CDS             complement(14..676)
                     /locus_tag="RD488_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7658722.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            901..1185
                     /gene="groES"
                     /locus_tag="RD488_002727"
     CDS             901..1185
                     /gene="groES"
                     /locus_tag="RD488_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDT7658723.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            1236..2861
                     /gene="groL"
                     /locus_tag="RD488_002728"
     CDS             1236..2861
                     /gene="groL"
                     /locus_tag="RD488_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDT7658724.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         1080 a          532 c          689 g          839 t
ORIGIN      
        1 tttatagtca tgtttatact agcccttttt ggacagctaa ttgaacaaga acaactaatg
       61 tgttcattcc tacgtgtgtg atcatcgatg tccagatccg accagttgct ttgtactcta
      121 ggctgaagaa gaaacctagg aaaaagtaga ttagcagatg accatcatta tgagcaaacg
      181 caaacagcaa agagctgatc actgctccga cccaaaaatt tgaatatcga ctgatgatcc
      241 ccagtatact gcggcggaat acgaactctt ccatgatggg tccagcaaca gttgtcgcca
      301 aaataaaagc gggtgcttcc atgatcatct ggatgatatt ttgtgtattc tcggaagggg
      361 ttgctttgcc aaacaataca gattctaaca tgacagcgat gctttgcaga atcaatgcga
      421 caaagattcc aaccaatcca taaataacaa tctttggagc agaagctttt tttaccgctg
      481 attcgatcgc taagggttca cgttgcttaa aataaaaaat agctaggaca acggcgccta
      541 gtatatacat gactgcagtt gctgtgatca attcagacgt agattttaca agtcctatcg
      601 aagctaggat caagggtgag ataaaaatta gaccatagca aaaaatgctg aggaagctat
      661 atttttttaa agacatgtaa ttcctccttt taagggataa caagcatgca aggcaagctt
      721 atatcgattg atttcaatta tatcataatt tcaataagca gctgtcagaa taaaatttct
      781 tttctttgat ttaaaagctt gcaaaaaaga gggagaatga gtattattaa aaatgtaggt
      841 tagcactcga aggttaagag tgctaacaga ttaaaaaaag agttatcgga gggatttatc
      901 gtgttaaaac cattaggtga tcgcgtcatt atcgaagtcg caaaagaaga agaaaaaact
      961 gtcggaggaa tcgttttagc ttctgctgct aaagagaaac cccaaactgg gacagttgtt
     1021 gcagtcggtg aaggccgttt gttagaaaac ggtgaaaaag ttcctgccgc tgtaaaagca
     1081 ggcgaccaag ttatgttcga aaaatacgcc ggtacagaag taaaatacga aggaaaagaa
     1141 tatctgatcg tcgcaggaaa agatatcatg gcgattgttg agtaaatttg gaagataaaa
     1201 aaataatcaa aaataatcaa tgaggtgaat caatcatggc aaaagaattg aaatttgcag
     1261 aagacgcacg cgcagctatg ttacgcgggg tagataaatt agcagataca gtgaaagtaa
     1321 cattaggacc taaaggccga aatgtcgtac tagaaaaatc ttacggctct ccattgatca
     1381 caaatgatgg tgtgacgatc gcaaaagaaa tcgaattaga agatcatttt gaaaacatgg
     1441 gtgcaaaact tgtatcagaa gtagcatcaa aaacaaatga tattgcagga gacggtacaa
     1501 cgacagcaac tgttctgaca caagcaatcg ttcgcgaagg tttaaaaaac gtaactgcag
     1561 gtgctaatcc tctaggcatt cgtcgcggga tcgaattggc aacaaaagca gcagtcgaag
     1621 aattgcataa tatctcaact gttgttgatt caaaagaagc cattgcacaa gtagcagctg
     1681 tttcttcggg ttctgataaa gttggacatt tgattgctga tgcaatggaa aaagttggaa
     1741 acgacggtgt catcacaatc gaagaatcaa aagggatcga aacagaacta gatgttgtag
     1801 aaggtatgca gtttgatcgt ggttacttat cacaatatat ggtaacagat aacgacaaaa
     1861 tggaagctgt tctagaaaac ccatatatct tgatcacaga caaaaaaatc tctaacatcc
     1921 aagatattct gccattgtta gaacaaatct tgcaacaatc acgtccattg ttgattattg
     1981 ctgacgatgt agatggtgaa gcattgccaa ctcttgtatt gaacaaaatc cgtggaacat
     2041 tcaacgtagt agctgtaaaa gctcctggtt tcggcgatcg tcgtaaagca atgcttgaag
     2101 atatcgctat tttgacaggt ggtacagtaa ttactgacga tctaggttta gaattgaaag
     2161 atgtaacaat cgaaaactta ggaaatgctt ctaaagttgt tgtagataaa gacaatacaa
     2221 cgatcgtaga aggttctgga gaaaaagaag caatcgaagc tcgtgtgcaa ttgatcaaaa
     2281 accaaattgc tgaaacaact tctgattttg accgcgaaaa attacaagaa cgcttagcta
     2341 aattagcagg tggtgtagct gttgttaaag ttggtgcagc tactgaaaca gaattgaaag
     2401 aattaaaatt acgcattgaa gatgcattga atgctacacg tgccgcagta gaagaaggaa
     2461 tggtctcagg tggtggtaca gctctagtga acgttatcag caaagtttct gctgtagaag
     2521 cagaaggaga cgtggcaaca ggtatcaaga tcgttgttcg tgctttagaa gaaccaattc
     2581 gtcaaatcgc tgaaaacgct ggttatgaag gatcagtgat tgttgataaa ttgaagaacg
     2641 tggaactagg cactggtttc aatgctgcta ctggagaatg ggtaaacatg gttgaagcag
     2701 gtatcgtaga cccaactaaa gtaacacgtt ctgccttgca aaatgccgct tccgtttctg
     2761 ccttgttatt aacgacagaa gcagtcgttg cagataaacc agaaccagca gcgccagcag
     2821 ctcctgcaat ggatccatca atgatgggcg gtatgatgta agaaaaagca acttgcttat
     2881 ctacaactga tcattagtga aagacagata aaaagaggct ggaacagaag cgtttaactc
     2941 caagaaataa gaagaaattc acggaaattg cttttcaaat ttttgtgaat ttcagcttat
     3001 ttccgaagga gttgcttctg cttccgctgt ttatacgtgt ttagagcgtg agacaaaagt
     3061 gttctttact tttgtcccac gctctttttt gtgtgtaatt ataatgaaaa tagttatttt
     3121 taatagttat aatattttat
//
LOCUS       DAPBBR010000118         3014 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPBBR010000118 DAPBBR010000000
VERSION     DAPBBR010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.126"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            178..360
                     /locus_tag="RD488_002729"
     CDS             178..360
                     /locus_tag="RD488_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDT7658725.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            463..747
                     /locus_tag="RD488_002730"
     CDS             463..747
                     /locus_tag="RD488_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658726.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            763..999
                     /locus_tag="RD488_002731"
     CDS             763..999
                     /locus_tag="RD488_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658727.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1021..1275
                     /locus_tag="RD488_002732"
     CDS             1021..1275
                     /locus_tag="RD488_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658728.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1357..1542
                     /locus_tag="RD488_002733"
     CDS             1357..1542
                     /locus_tag="RD488_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HDT7658729.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1609..2004
                     /locus_tag="RD488_002734"
     CDS             1609..2004
                     /locus_tag="RD488_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDT7658730.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1994..2371
                     /locus_tag="RD488_002735"
     CDS             1994..2371
                     /locus_tag="RD488_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658731.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2393..2767
                     /locus_tag="RD488_002736"
     CDS             2393..2767
                     /locus_tag="RD488_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658732.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLWKYKILFL
                     FWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1059 a          507 c          524 g          924 t
ORIGIN      
        1 gtttatgttt atgtatatgt atatgaatat aaacgtatta ggtacgaaca cttttaaatt
       61 cttttctggg ctttgttttt agggtagggc taaaaaaaac atcaccatct gatccaaaac
      121 agctcagaaa cgcatttaaa cgtatctgat accaatatta cagaaggagt gtatcgtatg
      181 attaacctat ttcttttagt gacagctagt acattattct ttactggaat atcactgata
      241 atttcctatt tgatctataa gaaagccgaa aatcacacaa gcaaagcaat cggactagcc
      301 gtttcatcct ttttaacttt gctgacttta tttgttactt tatcgttttc ttttgtttag
      361 aacagctgat ccattagcac ctttttctct ttacattata cacactgttg tgtataatgt
      421 atttgtaaac aagctaatta acttttagga aggagtgaca agatgctaac agctacttta
      481 cagcaaccta ctcacgttgc tattgcagaa agttatacaa ttaatgcagg gatcgttaaa
      541 cagctgatca aggatcgaga attcaaaaag tttaacagtc ggcaagcgta taacagacag
      601 ctaaagaaag ctattctaaa gcacaaagat tccttcatcg ggaacttgga aagtgtagat
      661 gttaaaactg tttcaacggc attttcagtt gttgaagtga ctattgacgg tcgcttgatt
      721 tctctatttg cttttggaat taattgatag ggagtgtgaa ctttggaagg taagactttt
      781 gcagaaattt ggactgaatt tattgaggta ccaactcgca ttgatccgat aacttctgaa
      841 aaggtattgg atgcagactt ctacaatctc aaagcaggta ctagccttga atgcgtttgg
      901 atgtatttag aagagcattt caaaggcgta acgctcggtc acgtcttata ccacaatggt
      961 gccgagtggg atgcaattgg aaatatccat ttttcttaat ataagaaagg agaacacaat
     1021 atgaattata ccgatgaaga acaaatcgct ttggaatacg ttttcacaaa tgaagaaggg
     1081 gaggaaattg aaaaagtctt gatcatttca tcaaaagact tggagaaggc tttggcttat
     1141 gaaccatacg aatcaaccgt aactgtcatt gaattcttag atacctatac ttctaatgat
     1201 acttgggaaa ttatgaatat ttgcaacgct aataacattc aatttgctga aaaaaccaat
     1261 aaatcatttt attagttttg caataaaaca tcctcttttt ctattgattc catacacaac
     1321 aatgtgtata atagattttg taaagggagg gtagctatgc ctaagacagc aagagaaatt
     1381 gtaaaaattc tcaaatctaa cggcttcaaa aagactggac aaactggcag tcatgcaaaa
     1441 ttttataatt ccaagactaa aagaacggtc gttgttccga tccacaatgg tgatgtacca
     1501 ctaggaacag aagctaatat ctggaagcaa gcagggcttt aacagccttg ccttcctatt
     1561 tggtattagg catactatcc tctcttacac tagaaaagga gcgaggaaat gaagacaaaa
     1621 aatatttttt atccggcaat cttcgagaaa gaaggagaag cttataacat cgttttccct
     1681 gacttaccgg aaatatctac ctttggaaat agtcttgaag aagcatattt aaacgctaag
     1741 gatgctttag gattagcgct atatagtgta ccagatgcag aatttcctaa accatcagca
     1801 gtggaagaat taactttgaa agccaaccaa gtggtagtaa tcatccaact aaacattaaa
     1861 cttttccgaa gaagcttaaa tacaaaaaca attagaaaaa atgttagtgt tccggaatgg
     1921 ttagttcttt tagggaagga gaaaaacata aacttctctc aactacttca aaaagcacta
     1981 gaagaagagt tgcttgaaaa gtaaaaagga gaccgaacct atgaaagcta cacacttaaa
     2041 ctatttctct cgaacgttaa tcaataatct attaaaagat acaactggca ttagcgttag
     2101 taccaaacac tttgccaatg atctaattat ttttgaggat aataacttgc gaattgagat
     2161 gtttattgaa caggcaaccc ctaactcaat acctgaattc tgctatacgc acactgaaaa
     2221 aatgaaacat gcaaaatcag ttaaagatgt tgaagcatta agtgaatcac taacgaacgc
     2281 tttaaacctc gttaagaagg caaaattgtt atttgaattt caaaccgact accacaatga
     2341 gttgcttgct caatctgaaa ttttagatta attgaaacag gagaagagaa agatgaaaca
     2401 aacacaaaca gaaaccgtta acgatacgct tgctgatcaa ttagcaggtt attataaatt
     2461 atttgagatg ggtaaagcac agcgcttgat ccactatctt tggaaataca aaattttgtt
     2521 tcttttttgg gaatcaacac taacattctc agttcttttt tataagtcag atttttataa
     2581 tcaacactta gttttaggga gttttttgct tatctacacc attttgatgc ttaatttata
     2641 tacctacatc acacttgaag aacacttagt aattagcgat gcagggatcg agagaaacat
     2701 caaaagggta tccttcaaga tcacgttaaa caagcctacc gataaaaagc tctcagaagc
     2761 gttctgagag cttttgacat tttcttgtat aattttatcc taacacatta caaagcacct
     2821 aattcgagct tatatcaagc aaatttgcta tttattactc aatacatatc taaaaattac
     2881 ttgatggaaa attagataca tggtaagcat gaaaagaaaa tcaatttgag cagatgcagt
     2941 acaatacata gcaatttaaa agctctcaga aggcttctga gagcttttaa tatattcttt
     3001 gataatttgt cttt
//
LOCUS       DAPBBR010000119         2979 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPBBR010000119 DAPBBR010000000
VERSION     DAPBBR010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.127"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1012
                     /locus_tag="RD488_002737"
     CDS             <1..1012
                     /locus_tag="RD488_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDT7658733.1"
                     /translation="ENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQR
                     NEKALMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLL
                     SEKNYPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTT
                     FFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSK
                     SFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNS
                     HNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINF
                     DK"
     gene            1069..1461
                     /locus_tag="RD488_002738"
     CDS             1069..1461
                     /locus_tag="RD488_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658734.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            1462..2901
                     /locus_tag="RD488_002739"
                     /note="aph(2'')-Ia"
     CDS             1462..2901
                     /locus_tag="RD488_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDT7658735.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT         1185 a          340 c          524 g          930 t
ORIGIN      
        1 agaaaaccga caaagtcaac gaaatggcta ttatgagcgc agctttacga cacgtgtagg
       61 cacgctagaa ttaaaagtac ccagaacacg tgatggccat ttttcaccca cagtgtttga
      121 acgttatcaa cgaaacgaaa aagccctcat ggcttcaatg ttggaaatgt atgtatcagg
      181 cgtttcaact cgtaaagtat caaaaattgt ggaagaactt tgtggtaaat ccgtctctaa
      241 gtccttcgtt tctagcttaa cagaacagct agaacctatg gttaacgagt ggcagaatcg
      301 tttattatca gaaaaaaatt atccttactt aatgaccgat gtactctata taaaagtacg
      361 agaagaaaat cgagtactct caaaaagctg tcatatagcg attggaataa ccaaagatgg
      421 cgaccgtgaa attatcggct tcatgattca aagtggcgaa agcgaagaga cctggacaac
      481 attttttgaa tacctaaaag aacgcggttt acaaggtacg gaactcgtta tttctgatgc
      541 gcacaaagga ttagtctctg ccattagaaa atccttcacc aacgtaagtt ggcaaagatg
      601 ccaagttcac ttcctaagaa atatctttac caccattcct aaaaaaaatt caaaatcttt
      661 cagagaagct gttaaaggaa tttttaagtt cacagatatt aacttagcgc gtgaggctaa
      721 aaatcgattg attcatgatt atatcgatca accaaaatat tcaaaagctt gcgcatcatt
      781 ggatgatgga ttcgaagacg cctttcaata taccgtacaa ggaaattccc acaatcgact
      841 aaagagtacc aatctaattg aacgactgaa tcaagaagta cgcagaagag aaaagattat
      901 tcgcatcttc cccaatcaaa catcagccaa tcgcttaatt ggagccgttc ttatggacct
      961 acatgatgaa tggatttatt cttcaagaaa atacatcaat tttgataagt agaaatggta
     1021 aaaacattgt atagcatttt acacaggagt ctggacttga ctgagtttat ggaagaagtt
     1081 ttaattgatg ataatatggt ttttgatatt gataatttaa aaggatttct taatgatacc
     1141 agttcatttg ggtttatagc taaagaaaat aataaaatta taggatttgc atattgctat
     1201 acacttttaa gacctgatgg aaaaacaatg ttttatttac actcaatagg aatgttacct
     1261 aactatcaag acaaaggtta tggttcaaaa ttattatctt ttattaagga atattctaaa
     1321 gagattggtt gttctgaaat gtttttaata actgataaag gtaatcctag agcttgccat
     1381 gtatatgaaa aattaggtgg taaaaatgat tataaagatg aaatagtata tgtatatgat
     1441 tatgaaaaag gtgataaata aatgaatata gttgaaaatg aaatatgtat aagaacttta
     1501 atagatgatg attttccttt gatgttaaaa tggttaactg atgaaagagt attagaattt
     1561 tatggtggta gagataaaaa atatacatta gaatcattaa aaaaacatta tacagagcct
     1621 tgggaagatg aagtttttag agtaattatt gaatataaca atgttcctat tggatatgga
     1681 caaatatata aaatgtatga tgagttatat actgattatc attatccaaa aactgatgag
     1741 atagtctatg gtatggatca atttatagga gagccaaatt attggagtaa aggaattggt
     1801 acaagatata ttaaattgat ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt
     1861 attttagacc ctcataaaaa taatccaaga gcaataaggg cataccaaaa atctggtttt
     1921 agaattattg aagatttgcc agaacatgaa ttacacgagg gcaaaaaaga agattgttat
     1981 ttaatggaat atagatatga tgataatgcc acaaatgtta aggcaatgaa atatttaatt
     2041 gagcattact ttgataattt caaagtagat agtattgaaa taatcggtag tggttatgat
     2101 agtgtggcat atttagttaa taatgaatac atttttaaaa caaaatttag tactaataag
     2161 aaaaaaggtt atgcaaaaga aaaagcaata tataattttt taaatacaaa tttagaaact
     2221 aatgtaaaaa ttcctaatat tgaatattcg tatattagtg atgaattatc tatactaggt
     2281 tataaagaaa ttaaaggaac ttttttaaca ccagaaattt attctactat gtcagaagaa
     2341 gaacaaaatt tgttaaaacg agatattgcc agttttttaa gacaaatgca cggtttagat
     2401 tatacagata ttagtgaatg tactattgat aataaacaaa atgtattaga agagtatata
     2461 ttgttgcgtg aaactattta taatgattta actgatatag aaaaagatta tatagaaagt
     2521 tttatggaaa gactaaatgc aacaacagtt tttgagggta aaaagtgttt atgccataat
     2581 gattttagtt gtaatcatct attgttagat ggcaataata gattaactgg aataattgat
     2641 tttggagatt ctggaattat agatgaatat tgtgatttta tatacttact tgaagatagt
     2701 gaagaagaaa taggaacaaa ttttggagaa gatatattaa gaatgtatgg aaatatagat
     2761 attgagaaag caaaagaata tcaagatata gttgaagaat attatcctat tgaaactatt
     2821 gtttatggaa ttaaaaatat taaacaggaa tttatcgaaa atggtagaaa agaaatttat
     2881 aaaaggactt ataaagattg attatataat atatgaaaag ctattataaa agacattagt
     2941 attaaatagt ttaaaaaaat gaaaaataat aaaggaagt
//
LOCUS       DAPBBR010000120         2945 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPBBR010000120 DAPBBR010000000
VERSION     DAPBBR010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.129"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..173
                     /locus_tag="RD488_002740"
     CDS             <1..173
                     /locus_tag="RD488_002740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658736.1"
                     /translation="DEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFI
                     ADLYKENGVELK"
     gene            170..1474
                     /locus_tag="RD488_002741"
     CDS             170..1474
                     /locus_tag="RD488_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7658737.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            1570..2439
                     /locus_tag="RD488_002742"
     CDS             1570..2439
                     /locus_tag="RD488_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7658738.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(2551..2871)
                     /locus_tag="RD488_002743"
     CDS             complement(2551..2871)
                     /locus_tag="RD488_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDT7658739.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
BASE COUNT          974 a          557 c          595 g          819 t
ORIGIN      
        1 aagatgaaaa attgaaaaaa agacaagaat tacttgaaga agtgtatacg gaacgttttg
       61 gaacaaaaga agagagagaa acggtccgtt tttattctgt ctccgaagag aaaaatctag
      121 atacgacatt cattgcagat ttgtataaag aaaatggggt ggaactgaaa tgatctcaat
      181 cacccataca ggtaatttat tcttagatac ttgtttgtct attatgtatt tttttctcgt
      241 ttcttatccg attttaggcg gatttgtatg gtttattggt gtctggtgtt atgtgttttt
      301 atacaaacat aagcaaaaag aatgggtaga tgttcccttg agtgtcgaac cgttcatcac
      361 gatcatggtg ccagcccata atgaagaaat tgtgatcgaa gatacaatcg agtatttgat
      421 gacgaaattg aattatcaca actatgaggt attagtgaca gacgatggtt caacggacca
      481 aacaccagaa atattagcta gactgatgaa aaaatacgct aatcttcgtg tggttcggat
      541 cgaaaaaaat aaaggaaaag cccacgcgtt taatatcgga cttgcctttg caaaagggaa
      601 attgatttta agcaatgatg cagacacggt accggagcca gatgcactga ttaggtatgt
      661 gaattatttc attcgccctg gtgcaagaca tattgctgcg gtcactgcaa atatggatgt
      721 ccaaaatcgt accaaattga ttgcaaaatc tcaaacggtt gaattctcaa gtatcgtggg
      781 catcattaaa cgaacacagt cagctgtttt cggtggtctt tatgcgtaca gtggagcaaa
      841 tacgatgtat cgaaaagaag ccttgatcga tgtgggcgga ttcagacaag atcgagcgac
      901 agaagacatc agtattgctt gggatcatca gttaaatgac tggttatctg tttttgctcc
      961 tgagattatc tttttcatgg aagtacctgt gacgttgaag atgctatatc gacacagaaa
     1021 acgttgggca aaaggtggaa cagaagtctg gctgacgaat ttcaaaaaag tgatgctcca
     1081 tccttttaaa catattggaa gaacgatcat cttcattgat caaacattga gtattgtctg
     1141 gtcaatattc ttttgtattt ccgtagttct ttttgctgga ttaatcgggc attatgtata
     1201 tcaaggaaac tacgaacaga tttatattac ttttacattc agttttgtgt tcatctgctt
     1261 tgaaatggtc gcaggatttt tccagttgct agcttcgctg attgtagatg atcgacgaag
     1321 aaaattgaaa taccttcttt tcgcaccact atatatgctt ttgttctgga tagtgaacgc
     1381 gataacgatc gtgacgactt tcattccagc agtcaaaacg attttaggtt atggaagcgg
     1441 gacatggaaa agcccggaac gtacaaaaaa ataaaagatg caccgttttt tagacaaaca
     1501 gcctgttgtg tttatggttc ttccaaacat ttttgcttat aataagaaat tagttaaaaa
     1561 gtagtaagga tgggaaaagt gatgaaaaaa agaatgaagc cgttaatctg gccaattgct
     1621 gtttccagta ttttcttatt gggacagaca gcttttgcgg aaacttctga acctgctcaa
     1681 acagaacctt caacaaccat aagctcttct ggtgctgaaa acggtgcctc ggaaacagaa
     1741 atgacttcca atgtaccgac agataattca ggagaaacga tttcatcttc agaagataca
     1801 tcaataaata gttctacctc ttctgaccaa atcgatcatt tgcaagactt ggaaaataaa
     1861 agaaaagaac tcgaagaagc attagaagct gcaaaaaaca aattgaaaga agaccaagca
     1921 gcaatcgatc aagatttagc tgatcttaaa aataaagtgg gaaatgaccg tgcacaactt
     1981 gagaaaaagc ttgccgaagc gaaagcaaaa gcggaagctg tccaaacaga tcttgacggg
     2041 aagatccaac aagcaaaaga attcaatcag caattaaatc aggttgctca aacagcttct
     2101 ggaaagctaa gtcaaactca agcggatatc acagcggcca gtcaagcaat ccacggaaag
     2161 atcagcgaag cacaaacagt tgctaatgat tttgaagcaa aaaaagctga cttagcagct
     2221 agtttccaac gaataaaaga tattttgcat tcggcaggag aaaaatcagt gacctctgga
     2281 agcacgacag aaacagttca gcaaacgaca gagccatcca aatcaacaag tcagactttg
     2341 ccaaaaacaa atgaaaaaac agcttctgtc agttattcct tagcaggggc gggtgtgtta
     2401 gtcgcagcag cttacggaat catccgcaaa aagaaataaa aaagagagga tgggaaggta
     2461 gagtacctcg aagttagact gaaaaatcta attcttgagt gccactacat gtcccatctc
     2521 tctttagtta ttaaaacaga tgtcccctac ttatctcgtg gagacagctg ttccactaca
     2581 tgtgaccatc agcatgccat tgtcgctgcc taatacttca tagtccattt ttacgccaat
     2641 gatcgcatca gctcctaatg cttttgcacg ttcggccatt tcggcaagtg cttcttctct
     2701 tgcacccatt agttcgtttt catagctttt tgagcggccg ccaaagatat ttcgcaaccc
     2761 cgcctccaag tctttaaatg catggatccc agtaatgacc tcaccaaaaa cgatcccttt
     2821 ataagctact acggcttttc cctctacact gttcgttgtt gttgtaatca ttcgatcact
     2881 cctctctttt aattaaagta taacaaactt caagaagcac tacacatatt ttcccaaaat
     2941 tagaa
//
LOCUS       DAPBBR010000121         2919 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPBBR010000121 DAPBBR010000000
VERSION     DAPBBR010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.130"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(37..1356)
                     /locus_tag="RD488_002744"
     CDS             complement(37..1356)
                     /locus_tag="RD488_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7658740.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1353..2006)
                     /locus_tag="RD488_002745"
     CDS             complement(1353..2006)
                     /locus_tag="RD488_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7658741.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2294..>2919
                     /locus_tag="RD488_002746"
     CDS             2294..>2919
                     /locus_tag="RD488_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658742.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPR"
BASE COUNT          956 a          476 c          322 g         1165 t
ORIGIN      
        1 ctatttttca ataactattg caaaattaca tcttaattaa gaaaatattt ttattttaaa
       61 gataaaaaat tcttcatcct gcaatacttt atattctata ttgtaattat tcagaatatt
      121 acttacaata tataaaccta atccattact attttcctta tttaaatcaa atttaacatc
      181 aaatatttta tccatattcg aaattttatt gttaccgtat gaattctcta tatataacca
      241 atcattaact atcccaatat taattacccc atttacatca gtatatttta ccgcattact
      301 aatcaaatta gatagaataa tctttaaagc tgtttttcct atataaacat tctcgtctaa
      361 tatataatta ttgacagtta ttttcttttg atttgctaat atttcatact tttttaatat
      421 gtcttctaat gtatcattta ttttcaaata ttcttcatca ttattcaaat tttctataga
      481 atgaactgat aatatttgag aaatattttt tgttaaacta tcaacgattt caatacattc
      541 attaatataa atatctcttt ctttatattt tccaatattg tatttcatgt tttccagtat
      601 tattttaaga ctagcaagag gggttttaag ttcatgggat gcacctttaa aaaagtcata
      661 ttttaacttt tctaatttta aaatttcttt atttttaaat tccaaatcgt caattgttct
      721 taataaagta gaatacaaat cattaatttg ttgttttaat tctccaactt catcattaga
      781 gctaactttt aaactcattt ttttatcaag tttcatcatt ttatcagtaa caatttttat
      841 ttcttgtata ttatttttta ttgattttgc ataaattaaa gaaataatag cagaaaataa
      901 aattgatatt aataaagaat atggtaaaaa tttaaggctt aaatctttcg catctttttg
      961 catatcagct gtagaaacaa attgtagatt tgttttttta ccatcattaa gctttatttc
     1021 tctttcttca attatcaaag aattactatc actttctaaa ttaacattta tattatcttt
     1081 gatttgtatt tcattcttat tatttttttc ttttatgaat acttttattt cactactctt
     1141 ggaataaaac tccaaagttt gttctatata ttttatttct tttccattca tattactaga
     1201 aatttcattt gccatattat gaatcttttc ttttctcgtc tccaaatatg ttttaggaaa
     1261 gataaaaaaa attaatgaat gaactaatat aattattatt ccaagaacag aaaatatttg
     1321 tatgaacatt tttggaaata tctttaattt tttcattttc tctccaattt atatcctaca
     1381 tttcttatag tagttataca gtctaattgt aatttttttc taagttcttt tatatataca
     1441 tctattactc gatcataagg agtttcttcg ctatctttcc atacataatc aataatttgc
     1501 attcttgtta acacttgtcc attattatcc aataaacatt ttaatacttc tagttctttt
     1561 gcatttacat ctatttcttc accatttatt ttagctgtat agctattaaa attaaccgat
     1621 agatccttat attcaaactt ctctaaatgt ccataattct tcttaattaa agaatctatt
     1681 ctagctttta agaccggcaa tgaaaatggc ttttctacat atccgtctac taaattagta
     1741 aatgcatcaa ttttatattc ttcatcacta aatgcagtca agattagaat tggtaaattg
     1801 cttttctttc taatttcttt caacacttct aaaccattta taaaaggtat ctgaatgtct
     1861 aagataacca aatttatatc gctattaaat tttgacaagg cttctcttcc atctttagct
     1921 tgaataacag tatatccaaa ttctgaaaga tattcactta ttccctctct tatcatatta
     1981 tcatcttcaa cagttaatat tttcatatat acctccactt aagcctatac actagatatt
     2041 atacagcata ttatggctct ataatatcta gtgttggtga cgccttctgt tgccaatact
     2101 ttttcttttt tttaataaat gcaaacagac accttgaaat cctttagaat aaagggttct
     2161 ataatatttt gtgttgttgg aaaatcgaag gcgattttct actaacactt tttcttcgtt
     2221 tcaactcaaa aagagactca cttttggtaa aatttagtcg accaaaacat caccctacca
     2281 aaggagtcgc tctatggata atcatactag aaaattactc ggattaacag ataaacattt
     2341 attttttgat gaagaatggc tgattgaaaa agaatataaa ggcgttcaag cgcagtttat
     2401 taaagggaga ttggatgact caccttccca ttgtgaacac tgtggatcga ttcgtattat
     2461 ccgcaacggt tcctatacga cacgtactca gatattgaaa gtcaaagaaa agttgactat
     2521 tttagaatta aaacgtaccc gttttctatg ctatgattgt gggcagacct tttctgcgaa
     2581 aacggactta gttgatgaac atcatcaact aacaaaggaa ctgaagcagg cgattctcat
     2641 agaactgtac gaaaatcaat cacgtaaact aatcgctaag aagtacttcg tctcggatgg
     2701 gacggtgaca cggatcttgc gtgaagcaac gaagcattac cagccacgta tgaacttcct
     2761 tccgacggtg ttgtgtatgg atgagttcaa atcaatgaag tctgtttctg gttccatgag
     2821 ttttatttgt gttgatggga caacccatca gctatttacg atccttgaag atcgcagact
     2881 ttacaaacta actcaatact tcctgcactt tcctagaaa
//
LOCUS       DAPBBR010000122         2786 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.131, whole genome shotgun sequence.
ACCESSION   DAPBBR010000122 DAPBBR010000000
VERSION     DAPBBR010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.131"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            78..2159
                     /locus_tag="RD488_002747"
                     /pseudo
     CDS             78..2159
                     /locus_tag="RD488_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
     gene            2239..2634
                     /locus_tag="RD488_002748"
     CDS             2239..2634
                     /locus_tag="RD488_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658743.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT          969 a          347 c          550 g          920 t
ORIGIN      
        1 tcatcgtcat tcctcctgct atctttttct attattctac cttatctgat agtagattta
       61 aaactttgca acagaaccag gggattaatc caggtggctt cgatggggta tatactccat
      121 atttagatac tgctgtaaaa gagttgcaga ctgatgcagg gtttaatgga agcgctgtaa
      181 ctggagtttt ggatgcgaaa tgggccaaag cgttatttga tatgagtgct tttgttcttg
      241 ttcccggcgg agatagtaaa attagaaaaa tgcagcaatg gttaaatgta aattatttag
      301 aatacacggg aataatgcct tgtgatggta tttatcaaag aaattcaaat caagcattaa
      361 tttttgcatt acaagctgaa ctaggatatt ctcccagtga agcaacaggg tcttatggta
      421 atgggacaac tagtaaaact tatcctgtgt ctgaaggtaa ctcgggaaac tatgtaagaa
      481 taattcaata tggattatat gttaatggtt attttgaaga cggtacattc gatggtattt
      541 tcactaaata tatgggttta gaagtactgg cattccgaaa atttatggta ttgcctgaat
      601 atactgaaat agcagatgtt gttgtaataa aaggactatt gtctagcgct ggagatatta
      661 gaagatctgc agatggcgca gatacttcta cgcaattaac tagatctcaa atccaaacat
      721 tggttgataa tgatataaaa atagttggta gatatcttac tggtactgtt ggaattggaa
      781 aagatgaacg aaataagtat ctaactacag aggaattgaa taatattttt tctaaaaatt
      841 tatctgtgtt tcctatctat caagatggag gtgcagcatt agcttatttt acttatgatc
      901 gtggcttatc agatggtaag aaggctatag atgcagcaaa aaatctaaat ataccattaa
      961 caacagttat ttattttgct gttgatctag acatgttagg ggaagaaatt cttgcatatg
     1021 ctggagaata ttttaagggg gtatctgctg taatgtcata tagcgggtat caaacgggtg
     1081 tttacggaac aagaaatgtt tgttctcaaa taatcaataa cgggtatgct tcgtttgcat
     1141 ttgtttcaga tatgtcgact ggttatagtg ggaatttagg ttttcctatg cctagacaat
     1201 ggtcttttga tcaatttgtt gaatttacca taggaagtgg caacggagct gttggtatcg
     1261 atttaatcgc tacatcgggt agagatagcg gatttaatga gttatcaaat gatactaata
     1321 atgataatta cattgccaaa tacaatcaga aggttataaa tcagatggta cgtgcgtatc
     1381 aatatctatc acaagctggt cttgataatc cttggaaccc tcatttgaca ttttatagat
     1441 atgtaaatta ttctggtttg tcatgggaca tcatttcttc tcctgtaaca gagcatgata
     1501 gaaaaattta tgatgaatat aggaataaat taactaatag cgagggcctg tataattatt
     1561 ttatagatcc taatactggt tcaataatag gtttgcctca cttaattgtg acgttacaat
     1621 cacagatgtt tctagccgac acaatcaatg atagtgtttc tgactttgca ggttggttag
     1681 gagatttaat gacttgctgg ggtgaagtta agaaattagg aatacaaatg gagcaaggtg
     1741 tatttgcatt agtaggtacg gctgcaggtg gaacatttag tctagaagat ttataccaag
     1801 atgttgacgc ggtaaatgtt tataccttag caaaaagaaa ttctgattca acagctttat
     1861 cggctttaaa aacgtactat tgtgataagg gtgctattga tagatttaat caatttgtta
     1921 agaacagatt tggttcttca gataaaatcg cttcagtaac aaatagttta ttagaaaatg
     1981 acgaaacagt tgatatctta ggtgtaggga taatttcatt tttcattgat aaaatagtta
     2041 ataattcact tgggacagat tttacttatc ttgattttat tggagatgag gggaaagttg
     2101 caaatggatt ttctgaaaaa attattcaat ttcaagaaaa tagaagtaaa cttaattaag
     2161 aatcgtttac tatttaaaca gtgtcctttt cctttttaaa tatatacgat aaaataagta
     2221 tatgaattgt aaaaggacat gatgattatg gaagaaatag aatggaataa tctgactcaa
     2281 aataataaaa ataattctgg atgtggaatt atctttatgt ttgttatagt tttgggaata
     2341 gtagtacttt taataactgt caagatagta gattactttg cgaatactcc tgaagaacaa
     2401 atacagagaa aacttcctga gtttgaaaga gtaccacctt atgatccaag agataattca
     2461 tttcaagtaa aaaaattaaa agagtctcca aatgaaatgt ggtttgaagt tacagttgaa
     2521 tcaagcgact tcaaagaaaa aaagaaagaa tacaattata ttgtaaaggc aaaagtatca
     2581 aaaagattta tttttaaccc taaattagaa atatatagtg ttgtaataga ataatagtgt
     2641 taaaaaaatt gtaaaagtta aagaagtcaa attctgatgt gaaaaataaa atataccatg
     2701 gaagacataa aagaaaaact ggataactag tttatttaat ggcagaccgt taaggcctgc
     2761 catttttatg tattttagcg gaataa
//
LOCUS       DAPBBR010000123         2766 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPBBR010000123 DAPBBR010000000
VERSION     DAPBBR010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.132"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            124..717
                     /locus_tag="RD488_002749"
     CDS             124..717
                     /locus_tag="RD488_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7658744.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKEAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDEYAIQPHYTNKENFDLGITETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            733..1632
                     /locus_tag="RD488_002750"
     CDS             733..1632
                     /locus_tag="RD488_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDT7658745.1"
                     /translation="MTPTQFKAKTRNFATEKHLNPQIVQRYYMMEKLLERIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTADPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERINEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKVERKQNFKRSQQMNQEMER"
     gene            1635..2120
                     /gene="ssb"
                     /locus_tag="RD488_002751"
     CDS             1635..2120
                     /gene="ssb"
                     /locus_tag="RD488_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7658746.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTATFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            2165..2398
                     /locus_tag="RD488_002752"
     CDS             2165..2398
                     /locus_tag="RD488_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658747.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGRDNSFWRLTKVTIAATAVILTAILPLYM"
     gene            complement(2557..2679)
                     /locus_tag="RD488_002753"
     CDS             complement(2557..2679)
                     /locus_tag="RD488_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HDT7658748.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
BASE COUNT          997 a          456 c          546 g          767 t
ORIGIN      
        1 tgttaaagaa ccagcagcgg attcaaaaag aaattgaatt agatcgataa atttctttct
       61 tgttaatata aaactaacat gttatagtta tgttagtttt atattaactt taggggaaaa
      121 gcaatgaaag acaaaatcca gtgtattttt gataaacata atgggaatct atccttgaag
      181 gatgctagaa gtgaaggatt atcgcctatg acgttagatc gattagccga aaaggacaaa
      241 atagaaaagg tagcaccagg tttctatacc ttaaaagaag cgttcgtgga tgaattgtat
      301 ctcgctcaaa gtatctattc cagagggatt ttttctcatg agactgcgct cgatcttttt
      361 caagtaggaa cgtatatccc taaaaagatc aatatgatgt ttcctaaagg atacaatgtt
      421 tcaaaggaga aattagacga gtatgctatt caaccgcatt acacgaataa agaaaatttt
      481 gacctgggaa tcacagaaac agaaagcttt tacggcaata aaattttagt ctatgattta
      541 gagcgaacgt tatgtgacat gtggaatcca agatacaaag caagcgtaga ggtaaaacaa
      601 gaagcattaa aagaatatat gacaagtacc agtagaaata caaataagct aagaagatac
      661 atggatattt taaaatcacc aaaagaaatg actttgtata tgttgccact ttattgagag
      721 gagtaaaggt gaatgacacc gacgcaattt aaagcaaaaa cgagaaattt tgcaacagag
      781 aaacatttaa acccacaaat tgtccaaaga tattatatga tggaaaaatt attagaacgt
      841 attgttgaat cgccttatca tgatgatttt gtattaaaag ggggatttct gatcggatca
      901 aaatacgggt tagaaaaccg ttcaactgtt gatattgata cgacttatcg aaattcgaaa
      961 ctaacaaaag aaaagttaga aactgttttt tctgaattaa cagctgatcc cacaaaagat
     1021 ggaattcgat ttgaattaaa gggattaaca gagacgaggg aagctgatta ttacccaggt
     1081 tttcaagcaa agtttattgc ttatcttgag aatgcacgtg taccatttaa attagatatt
     1141 acttcaggtg attctattat tccagcggca ttgatgtatg aacacaaatt aatgtttgaa
     1201 gataaaacga ttcatattcc agcttatcct acggaacaaa ttctagctga aaaattacat
     1261 gccacgttta gttttggaaa agataattcg cgcatgaaag atttttatga cctgtatatg
     1321 attccgaaat tagaacgtat caatgagaaa aatttgtata aaagtgttca aggaacattc
     1381 aaggaaagaa ataatcaatc ggtgtttaag catttgtatg accaggaaat gcctcaattg
     1441 gtgaaggatg aggggttgag ggaaaagtgg aaaagatacc aacaagaaaa ctattttgcc
     1501 aaagacattt ctttcgaatc tacactaact tccgttgatt ccctgatgca atcaattgta
     1561 gagcaagaga aggtagaacg aaaacaaaat tttaagagat cacaacaaat gaaccaagaa
     1621 atggagagat aaagatgatt aataatgtaa ctttagtagg acggttaacc aaagatccag
     1681 atttacgtta taccgcaagt ggcacagcag tagcgacttt taccctagcc gtcaaccgaa
     1741 atttcgcgaa tcaaaacggc aatcgagaag ccgattttat taactgcgtg atttggcgca
     1801 aaccagcaga aacaatggcg acattagcta aaaaaggcgg cttgatcggt gttgtcggac
     1861 ggattcaaac acgaacttat gacaaccagc aaggacaacg tgtgtatgtg actgaagttg
     1921 tagcagataa ctttcaacta ttagaaagta aagcagcgac agagagccgt gcgcacgctg
     1981 atcaatcgtc caccagtcca agcaccgcca cctttgaaca acgggataca gcgacgccta
     2041 acaacaatgg attgaacgct tcacagaatc catttggtgg acaatcaatc gatattagcg
     2101 atgatgatct accgttttag ttcgagaaag aaggagtaag catggcaaaa aaaatagtct
     2161 gacgatggat ctattgatac ccgtaattgc atttatagac gggatttctt tgggcgtcac
     2221 tgaaaatcct ttggtaaata gaattgcgaa aggatcacta tttcttgtat tcgtgtatct
     2281 tgtatgttct tatcttttaa aaagagcagg aagggataat tccttttggc gattgactaa
     2341 agtcacaata gcagcgacag ctgttatact tacggctatt ctaccgcttt atatgtaggg
     2401 ttaacgggaa atcgttgaac ttcttgcgaa atattgctat aatgaacatg aaaaagagga
     2461 gttgcgctaa caacccctca ttaacagcac cgattaaaga acggtggcag aatattagtt
     2521 atttggaaat aaccgctgac ctgctaaagt ggacggttat ttctttttgt catttttaag
     2581 catatttaca atcaaactaa tcaaagcaat ggtaaacata ccaaaaccaa gaatggtttg
     2641 aattgtctca tatgcggaca aaaggcttac tcctttcata gattttagca cttacattca
     2701 taagcaccac cacctttcca gaagtcgcca ccgtcttcaa actttactgt cttgactatt
     2761 atagca
//
LOCUS       DAPBBR010000124         2596 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPBBR010000124 DAPBBR010000000
VERSION     DAPBBR010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.133"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..2056)
                     /locus_tag="RD488_002754"
     CDS             complement(<1..2056)
                     /locus_tag="RD488_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDT7658749.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMA"
     gene            2181..>2596
                     /locus_tag="RD488_002755"
     CDS             2181..>2596
                     /locus_tag="RD488_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658750.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLA"
BASE COUNT          843 a          426 c          437 g          890 t
ORIGIN      
        1 aagccatatg cccatcaccc catatcttag aggtggcaag tttcctgtgt gcatgtatta
       61 ttttttgatt agctcctgaa agtgtatcca ctcgaatata atgatgattg acatagacaa
      121 gacgatcata ctttaaagaa tcaaatcctt cttttgaaac cggggaaaaa ccaatattgc
      181 aggactctga taaaagaact gctaataaac taatatccaa gtctttcatt ttggtgtcct
      241 tgtcacttaa gtggttaaat gattgagtaa gatttaactg ttggtttact tccaataaca
      301 aatctgacaa atcaatttta ggaagtaact gctgaatgcg acgtctaaaa gacttatctt
      361 cctttttttc atatgtcttt ttaagtctag agacaaccag gcgatctgca ttttctattc
      421 tggccatttt agaagtaggc caacgattta gcgcttcttt ataagacagt tccaaatcgt
      481 tctttaacca taaagacatt tcatttgctg aagaaggaag atctagttgt tctaataaaa
      541 cgtatttttg ttgaacccaa gttttctcat caatcaagca atccatagga ttgttatata
      601 agacactctg aggaatataa atatcatggc gttttaaaga ttgaattaac aattcgacag
      661 ctgcaatcaa tacacattta ttagtttgtt cagggtattc atgaatgtaa taaatccatt
      721 tctttggaag agtatgttta atagctccaa acattttgta agtaatcggc ttaggaaatc
      781 tattattaat gaaggtccag agttccttac agttgttacc gtagtcattg ctgtcaaatg
      841 ttagtgtagt taaaatatcc ggaataaatt ttctgaactt tcgataagtg ttcagaagtt
      901 cagaaatggc tattggttca cgatcatttt taaccaatag ccgaacttgc gatacagctt
      961 cggtaacatt ttcctcagaa tatttttcta agatacgatc gcgaagggat agttcattag
     1021 tatcagaatg actggacatt actaaatcta caatatctga aagtgtcgat gcggctcgat
     1081 ctagatcttt tatggtacga agacgttctt tagattcctt atttttggcg cgtctaaaaa
     1141 cagtttcaaa aaaattagat agtgctaaaa tttgttcatc catagcctta cgtttgtata
     1201 tgaaaataaa tgccactaac aacgccagtt ttttctgttc actcattcgt tgaattaatt
     1261 gagctttagc tttaaatgca taatttgcaa gaacttttat tttcccttca ggaatagatt
     1321 ccatcttcca tttttcagta gagaaagctt gaaattgctt tagtcggtca aaacctctgg
     1381 ctatttcttt atgactatcg tcagctaacg gggttctcaa aatgtccatt ttgattattg
     1441 ccccataaac tggagttcca attaattcta aatgattgag aagccgcttt ctctcatctt
     1501 cagttggaac caaagacaat tgtcggtata aatgctcttc agctttttca attgcactag
     1561 caacaaaacg agaaaaagta gtaattccag gtaaaacaat cttttcatcc agacattttt
     1621 ttagaagcat atcaaacaac atatctgaag attctgttgt atacagcgct ctatttaaaa
     1681 gccagttagc taggtatgtt tctatttccg gttggttgaa atcttgatat ccataatgtg
     1741 attttatcaa ttttgtgtgc tgatacctgg tctgtctcct gctatagtag ataatttctc
     1801 caggatcaat atttagttga gttgctacat aactcaatac attttgggga atattggtaa
     1861 gatctaatat aaaagttcct aaaaaacgta gtgagactaa ctgtagtgca aaacctaatc
     1921 tagtagctgg tcgtcgtata gtctccatca attctaaatc tttttcatgc aaataaaaaa
     1981 attggtttaa ttgttctgta ctaggttctc ctaaataaat gccaaatgct tttttgttac
     2041 ttttgatttc atccatttaa accctccatg aagtaaattt taagtctaca taaaatttat
     2101 ttttaaaaat gctatgatag cagtaaaact acaagtaaat tttacatgta aattatatca
     2161 cttttaaaaa ggagtttttt atgggaaaaa ttggctatat tcgagtatct tcacaagatc
     2221 aaaatttgga tcgacaattg gcaatgatgg aaggacttaa cattgataaa ttattccaag
     2281 aaaaagccag tggtaaagat actgagcgtc ctgagtttca aaaattacta aattatatcc
     2341 gtgaaggtga ttgcgtcatc gttacatcac tagatcgttt aggaagagat tatgaagata
     2401 taaaaaatac agttgctttt atgaaacaga aaaaagtagc gttaaaaata ttagatgcac
     2461 agtttttaga ttttaatact ggaaatgaac tcctggatac cgctatgttc gatatgtttt
     2521 tatcactgct aagttatatt gcacaaaacg agcgtgagaa aattcgtgaa cgtcagcggc
     2581 aaggagtatt attggc
//
LOCUS       DAPBBR010000125         2402 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPBBR010000125 DAPBBR010000000
VERSION     DAPBBR010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.135"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            207..2069
                     /locus_tag="RD488_002756"
     CDS             207..2069
                     /locus_tag="RD488_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7658751.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..2401
                     /locus_tag="RD488_002757"
     CDS             2069..2401
                     /locus_tag="RD488_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7658752.1"
                     /translation="MKMSDEALRIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          467 g          716 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taagaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
     2401 at
//
LOCUS       DAPBBR010000126         2364 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPBBR010000126 DAPBBR010000000
VERSION     DAPBBR010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.136"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            150..1451
                     /locus_tag="RD488_002758"
     CDS             150..1451
                     /locus_tag="RD488_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7658753.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1555..1755)
                     /locus_tag="RD488_002759"
     CDS             complement(1555..1755)
                     /locus_tag="RD488_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7658754.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            2151..2300
                     /locus_tag="RD488_002760"
     CDS             2151..2300
                     /locus_tag="RD488_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658755.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          768 a          453 c          408 g          735 t
ORIGIN      
        1 cgtacaaaaa aaccgtcttt tcttggctct ataatttcta ggactgatag aaaatcattc
       61 tatcggtccc ttttgagcat gaaaaaacaa aacatacaga agctccgtta gaattgaatc
      121 accacaacac aatcaaagga gcgttctgta tgcctgatct tcatcatatc aaactactac
      181 ttggaatcaa agataaaaac attttcatca caaatgtgga atcgaagagc attaagaata
      241 tcaagagtct tgttgtttct gcgacgttaa gtaaagaaat tcgtcgctgt cctttgtgta
      301 aacagatgaa tcatgaaggc atgatcgtta agaacggaaa gaaaaaatcg ctcattcaac
      361 ttaataaatg tgcgaaccaa ctgacttatc ttgctttagc gaaacaacgc taccactgtc
      421 gtggctgcca cacctatttt acggcgaata cctacattgt cgatagaaac tgctttatcg
      481 ctaaacaagt gcgctataaa attttagaag agctaactga aaaacaagca atgacgacaa
      541 ttgctaagca ttgcggcgtt tcttggtcga ccgtttctcg gacactcgct tctctgatcc
      601 ccatgacaaa agtaaaaaga aattggttac cgcgttgttt attaatggat gaatttcgtt
      661 cactgaaaaa tcaagtcggt ccctactcct tttcttgtat ggatggcgat actggaaaat
      721 tactggatat tcttccttca cggaagaaaa aggctctcgt ttcttatttt atgcaatttg
      781 aacgacgcgc acgattgaag gtaaaggtca tcgtgacgga catgaatgtt tcttatgcct
      841 ctctgataaa ggaatgtttt ccaaaggcaa aactcgttgt ggatcgtttt cacattgtca
      901 aacatctcat tcgtaaattt gaggatattc gcgtacgaat catgaaaagc tttgatcgaa
      961 acgatccaac acaagccaaa tattatcgac aattaaaggc gttgtctcgg cttctgatca
     1021 aacgacagga caagcttgtt tatgacaaat ggaccaaatg gcgcaatttt ggttgggcgt
     1081 atctcaccga aagtgaagtg gtggatcgtc tgctttcgat ctctgacgaa ttacgaatcg
     1141 cctattttta ctatcaagaa attcttcaag cgtttcacga caaagaggcg gacactttct
     1201 ttaaacttgt aagaacgatg cccaattccg ttccaaaaga actgcattct ataaaaaaag
     1261 cttttataaa ctatgaatcc ggcattcgtt tagccctcga attgccttat tcaaatgcca
     1321 aaatagaaaa tctgcatacc cacatcaaag cattgaaacg agtcgcttat ggctttcgaa
     1381 gctttcggaa aatgaagacc agaattttct tactaaataa tctgattacc tatgaatcaa
     1441 aaaacatcta aagtagaaaa ggaattctac cttagatgtt cttatctcac tctatcagtc
     1501 ctatttgaca aagagccctt ttctttcgaa aagacggtta aaagtcaatt tttattaagc
     1561 tttaacaatg tttgttgctt gagggccacg ttgaccatct tcaacatcgt aagacactgc
     1621 ttggccttct tctaaagttt tgaagccgtc accttggata gctgaaaaat gtgcaaatac
     1681 atcatttcca tcttcaccag tgataaagcc aaaacctttg tctgcgttga accattttac
     1741 tgtaccgtta ttcataaata aattcctcct gatacgtatc aatgtacgtt ttttcgttgc
     1801 aataaatatt tgataggcaa aaggagtttt atctatgtag atatatcgct caaattacgt
     1861 ttcaaaatag attactcatt taatatatca tgctttttct aataacacaa ggataatgca
     1921 atgaaatata aaattcattg tcttctattg tcttcgaatc gaagaaaaag ttgaataacc
     1981 gcgattgatt cactttttgt tttcttgttt atttgctttt atctgcaact tttgacttta
     2041 aaatttctta actatgaaaa cctttcaatt ggtggtatac ttataaatgg aatttcgtta
     2101 tcaacgcgtt cgttgccttt cagcaagtat ttaaagaaag gagaatggct atgacattct
     2161 ataacaaaga tatacaatat cgagtaacct tggatacaga tttgaatcta tttgtcgttt
     2221 ttgacaaaga aaataccaat catgtagcga caggtgttac gatcgaacaa gcagtgcaag
     2281 aattaaaaaa atctgcataa ggagtggaaa ccctcatatg gacgattctc gttcttctct
     2341 ttaaacgcat ctactggtag ataa
//
LOCUS       DAPBBR010000127         2363 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPBBR010000127 DAPBBR010000000
VERSION     DAPBBR010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.137"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(62..1444)
                     /locus_tag="RD488_002761"
                     /pseudo
     CDS             complement(62..1444)
                     /locus_tag="RD488_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1906..2187
                     /locus_tag="RD488_002762"
                     /pseudo
     CDS             1906..2187
                     /locus_tag="RD488_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
     gene            2261..>2363
                     /locus_tag="RD488_002763"
     CDS             2261..>2363
                     /locus_tag="RD488_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7658756.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQEL"
BASE COUNT          709 a          395 c          401 g          858 t
ORIGIN      
        1 acttgtattg tgcaatagtt ttttacaaaa aaaaggggtg cggatatttt tttggacctt
       61 tttaacaaat atatctttgc ttcttccgat attgaagagg gcttagccct cctaaagata
      121 acttaattcg ttgattatta taccaatgaa tataattatc caatttgttt ataaactgat
      181 tgatcgttgt attcttccag tcacgttgat aaaacatctc gttttttaat cgtccaaaga
      241 aaccttcgca cgctgaatta tctggtgaat aacccttttt agacatagag tgaagcaagt
      301 tggctttgtt ccaatagtcc aactaacaat agcaccatcg taacaatcga caagtggtga
      361 taagtagatt ttccctgcga gaattctaaa ttcagtaata tctgttaacc atttttcatt
      421 tggcttcttt gctttaaaat tccgatttaa taaattgggg tgtgcaggag aaatttcccc
      481 agcatacgaa gaatactttt ttcgtctaga aaatttaaca aatagatttt cctcagtcat
      541 caatctacgt acaacttttt cagaaagctt tttacccata ttttttaaag cttggtgaat
      601 tctacggtaa ccatacgcac agaagttatg attgaaaatc gtgataatta atttgacgtt
      661 ctttgtaata cttatctggt ttctcaagtg cttgtttttg ataaaaatag ctgcttttag
      721 gaaactggag ctgttgaaga agctctttca aggtgaactg atttcgtaag gcatcaatca
      781 atatcgtttt ttcttgattt gatagacaaa gaagattgac gcctttttct ttttttagca
      841 gttcagccgc tccttcgagt aatgcttttt cgagctgtaa ttggtgtact tgtttttgta
      901 agtcttctac ttcctttaaa agtagctctt tttgtttttc ctgatttttt aaagtcatac
      961 acaatggaaa atcctttcca agaaccgtgt ttttccattg atatagagta actctactaa
     1021 ttcctccaga ttcggctaaa tttttcctat tagtttgcgg tttatagaat tttttcaaca
     1081 cagcttcttt ttgatcttgt gttaacttta ccgcactttt tcggagtttt ctagctcctg
     1141 gtgcaagttc ttcacaccgc tgccgcaagg actctctatt aggataacca agcatgcgaa
     1201 tggttcgtgc ataacattga ccatattcaa aataatgatt caccgctatt cgtttttgtt
     1261 cttcagaata ctttgatttt tttcggtgct cctgatggag ctctccggat tccaaatact
     1321 ctttatacca tttccgtagt gcaccaatcg acggataccc taattctcga atggttgcag
     1381 cataagagca atcgtatttt aaaaataact gaattgccct tacacgctct ttgtgggaaa
     1441 acacacggac attcctccta agtttatttt ttcgtccagg attatgtccg cacccccttg
     1501 ctttctgatg acttattctg gttctttgag tgtcaatgca tagatgtgat gtagctagtt
     1561 agaaaaaaat tttgaatact ctttttttct ttcagactcc tttttaagta agattttgaa
     1621 gtgtgagtta cggggtcaga aacttaaaag tttttgatcc tttattttca agtctgattt
     1681 ggcagctttt cggcagctca tttatttatg gtcagaaata gatgctgaaa ttttaatcta
     1741 ttagcaaata gtccagaacg tatgaagagg agtcggatat catttgtcat taacaccata
     1801 aatatttata aaattcgtgt tcacctacaa ttaaatttaa tatataatat tcgttgtaag
     1861 ggcttataat tttttgttaa tgaacaagat aggaagaaac atttaatgga cagttttcag
     1921 agattgtcac tagtaaatca atttgagtta ttggctaaat ttgaggacca aaacagatct
     1981 tattatgaaa gaaaaatcga aatattgaga gaaggttacg agtatcatta tgatgatgaa
     2041 atttggagtg atctttctga gccatttccg aaagaagatt ctcgatttgt attagatgta
     2101 ttgaacatgt atcgagatat caattttagt aaatcaaagc taaacttaga tgaaaaccaa
     2161 attactaatt catactatac tcatttcggt tctgttgcaa agttttccaa aaaatctatt
     2221 ttagtgtaaa attgagaaaa aagacagaga ggacagagta atgaatcatt ttaaaggcaa
     2281 acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt acaatctaag
     2341 ctatcgtgaa gttcaggaat tgt
//
LOCUS       DAPBBR010000128         2337 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPBBR010000128 DAPBBR010000000
VERSION     DAPBBR010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.138"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            233..961
                     /locus_tag="RD488_002764"
     CDS             233..961
                     /locus_tag="RD488_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDT7658757.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRTNESDYNKRDQVLL
                     VKLNEEISVEEAVRTFNASDMVNYAEPNYVVELEPLNDVEEPNTTDSLGNRSIILNDP
                     NWSKQANLREISMPSAWEETKGSKDVKVAVIDSGIDYQHEDLSGNVDESLRYDFFDDD
                     TDPMDTMGHGHILPGLLVLKQTTN"
     gene            991..2118
                     /locus_tag="RD488_002765"
     CDS             991..2118
                     /locus_tag="RD488_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDT7658758.1"
                     /translation="MVPIRVFGSSGGTSLAILTEAINYASQKGFPIINFSIGSVVYSS
                     TEEAIKNYPGLFVAAAGNNGIDMTDKPFYPASLDIPNIITVGNSSGYERSSDSNYSKT
                     GVDLFARGFRVFSTFLGSKYTYMSGTSMATPHVTGSAALALSLDPDLSTDELKKIILN
                     SVDSFYELSDLCLTGGRLNTNNVVRQVTGKLTASNITLRLNSEWSDEIAKEMCHVHWI
                     DQSGNDLTDQVVVLKNEVDTSNFGDYEVVFASPDLTDQISVTVTVPRLRKLTLGKETA
                     TIDIGSAWDSVIAIDTFQVKAIDDFGNDVTNQVQVTINADIDTINSIQAVIKFEVPEL
                     GLAQIGRLNITAKNSTINGLNEVSIEHVKKIMSFSKKNLDI"
     gene            2073..2337
                     /locus_tag="RD488_002766"
                     /pseudo
     CDS             2073..2337
                     /locus_tag="RD488_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          806 a          319 c          497 g          715 t
ORIGIN      
        1 tttaaacggt agttacttag ttcttctttg atttgcgtga aatagagggg atttattttt
       61 ctggttacgt gattaaaaaa tccaaaaaat gagcatagga acggttatga ttttagggtg
      121 tgttttaatg agatattgtg atttcattaa caagtgtata ataatctgtt gttgagttag
      181 taaataagta atagagctaa ctctaaaata aaactattag gaggagatgt aggtgaaaaa
      241 gtttaaaaag aaaatatatt taggattggt tgttggggtg agtatgtttg ggttcatggc
      301 tcatactaaa caagtaactg cagatactaa ccaaaaagaa aggattatga gccaattaga
      361 tgactctcaa atagagtatg tacccaatga gctaattgtc agtttaaagg ctacacaaag
      421 aatttcaaca gagaaaaata aaccgcaaaa tttattgggt gtaaaagtta tggtggaaaa
      481 agatttgacc cttaggacaa atgaaagcga ttataataag cgagatcaag tattattagt
      541 gaaattgaac gaagaaatta gtgtggaaga ggcagtaaga acatttaatg cttctgatat
      601 ggtcaattat gcagagccaa actatgtggt tgaactagag ccgttgaatg atgttgagga
      661 gccaaataca actgattctt taggaaatcg atcaattatt cttaacgatc ctaattggag
      721 taaacaagct aatttaagag agattagcat gccatccgct tgggaagaaa ccaagggttc
      781 taaggatgtg aaggtagcgg tcattgattc aggaattgat tatcaacatg aagatctttc
      841 tggaaatgta gatgaaagtt tgagatacga tttttttgac gatgatacag atcctatgga
      901 tactatggga catggacaca tattgccggg attattggtg ctcaaacaaa caacgaatta
      961 ggtgttgctg gaataaattg ggatgttacg atggtaccta tacgtgtatt tggtagtagt
     1021 ggaggtacca gtttggcaat cttaactgaa gctattaatt atgcatccca aaaagggttt
     1081 ccaattatca attttagtat aggtagtgtt gtttatagca gtacagaaga agcaattaaa
     1141 aactatcctg gattattcgt agcagcagct ggaaataatg ggatagatat gactgataaa
     1201 cctttttacc cagcttcttt ggatatacct aatattatta ctgtaggaaa ttctagtggt
     1261 tatgaacgaa gttctgattc aaattatagt aaaacaggtg ttgatttatt cgctagaggg
     1321 tttcgtgttt ttagtacatt tctaggaagt aaatacacgt atatgtcagg tacctcgatg
     1381 gcaacacctc atgtcactgg tagtgctgca ttagcgttgt cactagatcc tgatctatct
     1441 actgatgaat taaaaaaaat cattttaaat agtgttgatt cattttatga actatctgat
     1501 ttatgtctta cagggggaag actaaatacg aataatgtcg tacgacaagt aacgggtaaa
     1561 cttactgcat ctaatatcac attaagatta aatagtgaat ggtcagatga aattgctaaa
     1621 gagatgtgtc acgttcactg gattgaccag tcaggaaatg atttgacgga tcaagtggtt
     1681 gttctaaaaa acgaagtgga tacatctaac tttggcgatt acgaagtagt atttgcatca
     1741 cctgatttaa cagatcaaat ctcagttaca gtgaccgtac ctcgattacg taaacttacg
     1801 ctaggaaaag aaacagcaac cattgatatt ggttccgcat gggatagtgt catagccatt
     1861 gatacttttc aagtgaaagc tatagatgat tttgggaatg atgttacaaa tcaagtacag
     1921 gttactatta atgctgatat agatacaatt aattcaattc aagcagtgat taagtttgaa
     1981 gttccagaat taggcttagc ccaaattggt agactgaata ttactgcaaa aaatagtaca
     2041 atcaatggat tgaatgaagt tagcatcgag cacgtaaaaa agattatgtc gttttcgaag
     2101 aagaatttgg acatttagag ggtgatacga ttgtcggcat ccaccataaa agtgtcgtca
     2161 tcacactcgt tgagcgactt tcgaaagcca ttatcgcctt gaaaccagaa ggccgtaagg
     2221 cagttgatat tgaaaattcg attaatgaat ggcttcaatc cgtacccaaa aatcttttca
     2281 aatcaattac ctttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatg
//
LOCUS       DAPBBR010000129         2145 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPBBR010000129 DAPBBR010000000
VERSION     DAPBBR010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.139"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            727..945
                     /locus_tag="RD488_002767"
                     /pseudo
     CDS             727..945
                     /locus_tag="RD488_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            1205..1459
                     /locus_tag="RD488_002768"
     CDS             1205..1459
                     /locus_tag="RD488_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7658759.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            1460..1777
                     /locus_tag="RD488_002769"
     CDS             1460..1777
                     /locus_tag="RD488_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7658760.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          736 a          333 c          393 g          683 t
ORIGIN      
        1 atcaagcaaa tttgcccttt gtatttttct ttagttaaac aattttcctc gaaatagata
       61 tttaggtcta gaatatttag ggtatctttg ataagctgag tatgagacat cttgaatcct
      121 cctatgaatt ggtagccaaa ttaattctaa aggatttcag ggtgtctttt ctatattttt
      181 ttatacaaaa aagatgttgg tgaagttcac caacatcaaa aagtatagag cctttcatta
      241 tatcaccaaa ccccatcagc gtgcaggctg atggggtttt tttacgtttc tatattatag
      301 aattaacggg taggcttact gtcttttttg gcaattttgc aatcaagcca tttgcagagg
      361 taactgcaca ctacatctgc aaatggcttg attgcaaaaa caaaatcaaa aaggtatttc
      421 attatatctc ctcctcccct tgacagatta ggccggggta gcagacagca aaactattat
      481 aacataactg aaatacctaa atgacatata cagatatgat aatttatgta ttgatttttc
      541 taacaaaagc acatatttta atatatacta cctattttag gtagtatata tttttagata
      601 caatatcgat cagttttgag gaaatgaaat tctagatatt ttttgctaaa tagagttact
      661 ttcaatattt tttaacgtaa ttaggcagaa gtcactcatc ctctataggt ttgtgatgaa
      721 attgccattg atccatttaa gtaagagcaa aaaactggag gtttatcagg taattggtct
      781 aatggattta agtatgcggt caccgtgtat agagttgctt atgagattca agaaaataaa
      841 gttattccag tattgctata tggaacacat aacaattttt atgaattagc cgagaacact
      901 cgcaacttta ttcgtgtaga tgaatcggct tcggttgagt tataacttta gctatatcaa
      961 tcaaccgacc gacatatgtt aaatctatat ataataaaaa tacctactta aatggatgtt
     1021 aacggaagtg tatggtgagt agttcactcg tattttgata tcgtttgtat atgttttcag
     1081 cgttctaagt ggcttatttt gtccaataat aatatggagt ggaatccctt aagaaacacc
     1141 gttggcaatt gttgttataa catgttataa tttattcatc aaaaactaaa aggagtgtga
     1201 taacatggga aaagaactaa aggttagaaa gatcggcaat agcgtgggag tgatccttcc
     1261 aagctctctt ggattaaaaa gcggagacac tatccaagcc aaacaagaag gcaacttatt
     1321 catattagat actactcaaa tagcaaaaga acacgatcgc aaattgattg aagaaagttt
     1381 ccaagacttt gagaaaggtt taacagtttc agaaattgaa atggtaaaag ctttcggaaa
     1441 atacggctgg agtgaataga tgaaagagta cacgctagtt tattctaaaa gtttccagac
     1501 cagccttgaa acgataatag aagaatggga aaatgagctt gctctgtctc cagccagcat
     1561 aaaaagattt gtaggtgcga tccagaaggc tttagaacta accaaaaatt ttccaactat
     1621 gcatgaggaa gtttccgaaa tctatggaat ggatatccca acatatcgga tcgtgatcgg
     1681 caaaagctat gccttatttt atcggatcga ccatgaaaaa aaagagatac ttgtaggacg
     1741 tattttccaa tctaaacaaa tgaaactagg cttttaacaa taattaggca aaagtcgctc
     1801 atcctctaca ggtgggtgat taatgccgct cgatatggtt gttaaccgtc ggttactcga
     1861 agattgatat ataagactta gtaccttttt attttgctcc atgttatggc cgaaggtcta
     1921 aagatacaat cattagtcta gagaaaaatt aagaaccgta ggaactacgg ggatcgcttg
     1981 gtgaataaga gacactgcta ttagtgaaaa aataagatat caagtacgct ctattcccaa
     2041 aaatttcgtg actttactca tgagaggttc aagtagtata tttttaatca aaattgacgt
     2101 aacttttaat aaatactacc taaataaggt agtatttatt tttgt
//
LOCUS       DAPBBR010000130         2101 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.140, whole genome shotgun sequence.
ACCESSION   DAPBBR010000130 DAPBBR010000000
VERSION     DAPBBR010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.140"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            360..902
                     /locus_tag="RD488_002770"
     CDS             360..902
                     /locus_tag="RD488_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658761.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1058..1432
                     /locus_tag="RD488_002771"
     CDS             1058..1432
                     /locus_tag="RD488_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDT7658762.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
     gene            complement(1539..>2101)
                     /locus_tag="RD488_002772"
     CDS             complement(1539..>2101)
                     /locus_tag="RD488_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HDT7658763.1"
                     /translation="NVLDRTFTQEQPLEAIVTDLTYVRVRKKWHYICLILDLFNREII
                     GYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDRGKEFDNQTIHEILNGFGITRSLSR
                     KGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETP
                     IQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          748 a          328 c          400 g          625 t
ORIGIN      
        1 ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt gacatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcaa attgatgaag cagatcccaa
      181 agggctgctt catcaatttt ttcgtaagtg tccgtacact tactgtgctt gctcatatat
      241 taatcgatca tatactaatc gtgtaagaac aactttaagc ataatactta tattgttata
      301 ccatagtttg gaaaaataaa aaattatatt tcatcaacgt ttcataaaag gtgtgtagaa
      361 tgttattgaa agtagctata aaatgctatt gtgtaaaaaa taaaggagga ataatttatg
      421 aaaaaatagt accaagagga gcatgcctat tacttgcatt atgtttgagc ttaagcgcag
      481 ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga aggacaatcc ataagttctg
      541 aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga aacttttaag ccatcagatt
      601 atacattgga ggcaaagaaa gaatatgttt atgaatattt agggcttaaa tttaaactct
      661 cagacaaatt tagaaattat atagctgata aaaagatagc gatgttagat gatcaaagtc
      721 ctatagataa agaactaaag tatgctattt tgacatttga gaaaatgaca gaagaacaaa
      781 agaatgcagt tatagaaaag atgggcgatg gatataaaaa ttggcaaaat gagcttgaaa
      841 gaattgggac tattggtata tttgaaaaaa atacatcaga agaaaaaaat ctaaaattat
      901 aaaatgtgat actcatacta aaataggagt ttcaagtgat ggaaaatacg attgctattt
      961 aagcacaaat agcggagctg aaagtaatct tctggatgaa ttaaaaagaa ctgagattca
     1021 aattatagat aaaaaagaac gtcctaaaaa tggttttgtg ctatcagaaa aaactgattt
     1081 agaaaataca gaagcattta acaaagaatc ggttaaagat ttacgtaaac taccaacaaa
     1141 ggacataaat ggcaaggatt ttacaagtaa agattttgag aagtatgatc ttactatggt
     1201 aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa attcctgatt tggttgaggt
     1261 tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga gttgttacag atcctgttga
     1321 tgataacggt gaaaacaagg aagcaattga aaagtcaaag ttaatacatg aaaagacaaa
     1381 ggcttcatat cctttcttaa tgccagatgt ggaatggcaa cacttttttt gacaaaaatt
     1441 ataaggtgtt gtgaatgctg cggtgttatg gctccgattg cccttgacaa tgagcatcct
     1501 cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc tccagaggta
     1561 tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg aatttggatc
     1621 ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg cacataatca
     1681 aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac gaattctact
     1741 ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc cttcctactc
     1801 aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt atcaaattcc
     1861 tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat ccgtccaaag
     1921 gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat aatttctcga
     1981 ttaaacaaat caagtattaa gcagatataa tgccactttt tcctcacgcg aacataagta
     2041 agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc taatacattc
     2101 g
//
LOCUS       DAPBBR010000131         1934 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPBBR010000131 DAPBBR010000000
VERSION     DAPBBR010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.142"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..563)
                     /locus_tag="RD488_002773"
     CDS             complement(<1..563)
                     /locus_tag="RD488_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDT7658764.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="RD488_002774"
     CDS             complement(750..1400)
                     /locus_tag="RD488_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658765.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
BASE COUNT          685 a          385 c          233 g          631 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttt
//
LOCUS       DAPBBR010000132         1844 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPBBR010000132 DAPBBR010000000
VERSION     DAPBBR010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.143"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..613)
                     /locus_tag="RD488_002775"
     CDS             complement(<1..613)
                     /locus_tag="RD488_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658766.1"
                     /translation="MTETKFIQDPWSKMTTRNGLRGDEAISALQKSIRRGKEKEACEF
                     AYEMYITSPQFEEKLWRRLLAISVEDVGMGNPMAAIMINNLNAMRKEFQYNESDRAMY
                     FFHAIRYLCQSEKDRSSDLLKNIVIKSFAMGYIPEIPDIALDKHTVRGQAMGRGSEHF
                     LHEASKVIPQAKVDNDYKEQYEKIIETYDPDHVVPSTFSFNPWQ"
     gene            654..1346
                     /locus_tag="RD488_002776"
     CDS             654..1346
                     /locus_tag="RD488_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7658767.1"
                     /translation="MDVEMLIDKYQLNDSEAEVLRFMKKNRQSLKNIGIRDVAKASYV
                     STATIINMAKKIGYSGYSELVFALGNSQSDITMPSTFSNEEKEAFIHLMSAYRDKRIM
                     ILGSGFSQNLANYFSESLNLYGFRATANSHLEFLRQQVQQDILLFIISNSGDTVRLAE
                     LAKIANDHFIDVIAFVGQKNSKIGTLATLTISTETYIPQKISDYQPNLFFGTTLNQFE
                     LLLSAALKAIYK"
BASE COUNT          563 a          347 c          329 g          605 t
ORIGIN      
        1 cttgccaagg attaaatgaa aacgtacttg gcacgacgtg atctggatca taggtctcga
       61 tgattttttc gtattgttcc ttgtagtcat tatcaacttt tgcttggggg atcactttac
      121 ttgcttcatg caaaaagtgt tctgaaccac gccccattgc ctgtccccga acagtatgtt
      181 tatccaacgc aatatcagga atttctggaa tatatcccat agcgaaactc ttgataacaa
      241 tgttcttaag taaatccgat gaacgatctt tttcagattg gcataggtaa cgaatcgcgt
      301 ggaaaaaata catcgcacga tcggattcat tgtattggaa ttctttgcgc atggcgttta
      361 agttattgat catgatggcg gccataggat tgcccatgcc cacatcctca acactgatcg
      421 ccaatagcct tctccagagt ttctcttcaa attgtggtga ggtgatatac atttcataag
      481 caaattcaca tgcttctttt tcttttcctc gacgaatcga tttctgtaat gctgagatag
      541 cttcatctcc acgtaagccg ttacgggtag tcatttttga ccacggatct tgaataaatt
      601 tcgtttctgt cataatataa tactcctatt agataaaatt tgaggtgaat cttatggatg
      661 ttgaaatgct tatagataaa taccaactga atgactcaga agctgaagtc ttacgattta
      721 tgaaaaaaaa tcgtcagtct ttaaaaaata ttgggattcg tgacgttgcc aaagcatcgt
      781 atgtttctac tgcaacgatt atcaatatgg cgaagaaaat tggatattcc ggttatagtg
      841 agttggtatt tgctctagga aacagccaat ctgacattac gatgccaagc acattctcca
      901 atgaggagaa ggaagcattc atacatttaa tgtctgcgta tcgcgataaa cggattatga
      961 ttcttggctc aggtttttcg caaaatctag ccaattattt ttcggaatct cttaatctat
     1021 atggatttcg tgcgacggcc aatagtcatt tagaatttct tagacagcaa gtgcaacaag
     1081 atattctgct ttttattatt tccaattctg gtgatacagt tcgattagcc gaattagcta
     1141 aaattgcgaa cgatcacttt atcgatgtga tcgcatttgt tgggcaaaaa aattcaaaaa
     1201 tcggtacgct ggcaacatta accattagca cggaaaccta tattccacaa aaaatatctg
     1261 attaccaacc aaatcttttc tttggcacga cactgaatca atttgagctt ttgttgagcg
     1321 cggcgctgaa ggctatttat aaatagaaga acgctgtggc cactgtttct tcaaaatcta
     1381 gtataaagaa tcttctttag aatgtaattg ttttctgtgt gttctgaaca tgtttaggaa
     1441 tttccaaact tgtttagaaa actttctcat tccctccgct gtagaattga actcacataa
     1501 aaaacatcta aaccaaaata tctacaagct tggaaaggat aataggttgt tattaaaaat
     1561 aatttttatt cctgaacctg aataattcat agctttaatt ctttggcaca ttttattgaa
     1621 atatgtatca ctaatatccc tatcaactga ttttgactaa aaagttactt caaacattca
     1681 ctgttcaaaa atattgagga ataaattttg ggtgtaaggc attttgagca tacttctccc
     1741 tggataactt cccagtaaaa aaatcgttag attgttggat tagatccatt gactgcctcg
     1801 cctcaggcga gcaaagaccc tgtagaattc attctgatac acat
//
LOCUS       DAPBBR010000133         1841 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.144, whole genome shotgun sequence.
ACCESSION   DAPBBR010000133 DAPBBR010000000
VERSION     DAPBBR010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.144"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..549
                     /locus_tag="RD488_002777"
     CDS             <1..549
                     /locus_tag="RD488_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7658768.1"
                     /translation="TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYL
                     YRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKRFDEPKVVVTDKAPSITSAFKKLKE
                     YGGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTR
                     KEGTLFGFSVCTEIKVLLGIPA"
     gene            528..815
                     /locus_tag="RD488_002778"
     CDS             528..815
                     /locus_tag="RD488_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDT7658769.1"
                     /translation="MIGNPSLNHRYRKGFYSLFKTLQQNQNTNSYQAAILTAVNLGGD
                     TDTTAAVTGALAGILYGGEVIPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            884..1150
                     /locus_tag="RD488_002779"
     CDS             884..1150
                     /locus_tag="RD488_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7658770.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            1140..1409
                     /locus_tag="RD488_002780"
     CDS             1140..1409
                     /locus_tag="RD488_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7658771.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT          623 a          332 c          395 g          491 t
ORIGIN      
        1 acaatttatc gttgggtgca agaatatggc aaactacttt atcaaatttg gaaaaagaaa
       61 aataaaaaat ccttttattc atggaaaatg gatgaaacgt acatcaaaat taaaggaaaa
      121 tggcattatt tgtatcgagc catcgatgca gatggtttaa ccttggatat ttggttacgt
      181 aaaaaacggg acacacaagc agcgtatgct tttcttaagc ggttagtgaa gcggtttgat
      241 gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt taagaaacta
      301 aaagaatacg gcggctttta tcaagggaca gaacatcgta ccattaaata cctgaataat
      361 ttgattgaac aagaccatcg cccagtaaag agacgcaata aattctatcg aagtttacgc
      421 actgcctcta ccacgattaa aggcatggaa gccatccgag gattatataa gaaaacccga
      481 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
      541 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      601 accaaaatac gaatagttat caagcagcca tattgactgc ggtcaattta ggaggggata
      661 ctgatactac tgctgccgta actggtgctc ttgcgggtat tctttacggg ggtgaagtga
      721 tccctgaaaa ttggagaaaa tcgcttcaaa atgaccagct tcttaaaacg atcagtcaga
      781 gattttgcga taccgtgcta tctcaaagaa tttgaataat ggatatgatg caaatcttgt
      841 ttgtactaac gttgtattga caaaaaggat tttatttagt acaatgttag tacaaatgat
      901 gaacggaggt agaatcatgt ctcaatcaac cattacattt aggattcccg acgatgaaaa
      961 agaactggta ttagaatatg caaaagcaca caattcttca ttgaccgaac tttatcgaaa
     1021 tgctgtactg gataaaatcg aagatgaaat cgatctacgg actttacgga gtgcaattga
     1081 agtttccaaa gagaaaaaag agagtggtat ttctcaagag gaaatggaga aactgctaaa
     1141 tgaattataa agtcatctac atgccgcaag cccagaagca attaaaaaaa atggacagaa
     1201 accaagctaa aataattgtc gcctggatca gaaagaattt agaaaacacg actgacccgc
     1261 gtcagcacgg aaaaggtttg actggaaata agagtgggga atggcgctat cgaattggaa
     1321 actatcgaat attggctaat atttgtgatt ctgaaattga aatccagata ttctcaattg
     1381 gacatagaag tacaatatat aaaagataac cgtttttgga acgaagtaga gtttcgaaag
     1441 tcaatgtata atcttttgaa ttttgcataa taccacaggt agaaactacc cgatactatc
     1501 ggttggtttc tgctttttta tttggtcttg aagaagaaaa cgagtgatct gtggcaaaga
     1561 aagaaacaaa aaaaggacaa aactgttgct tcgcctgcgg tgcagtcgcc cttggatcaa
     1621 agcgcgtctg ttttcttttg gctagtggca aggtctaact gcttggtggc tacgtgcctt
     1681 cgccagtcgc agctgccttg gttggctgcg tgcctccgcc aagtcggccg acctcaccat
     1741 ttttgcctac gcaaaaaggc caaaaggatt taaaggaatc cgtcgaagca tagctccaac
     1801 ttctccggat caaaaagcgg taggaacccg tgccgggttc c
//
LOCUS       DAPBBR010000134         1755 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPBBR010000134 DAPBBR010000000
VERSION     DAPBBR010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.145"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(148..231)
                     /locus_tag="RD488_002781"
                     /pseudo
     CDS             complement(148..231)
                     /locus_tag="RD488_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            580..1665
                     /gene="xerS"
                     /locus_tag="RD488_002782"
     CDS             580..1665
                     /gene="xerS"
                     /locus_tag="RD488_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HDT7658772.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT          649 a          299 c          246 g          561 t
ORIGIN      
        1 atatgcttct atcattacaa gctcgtttgg tgtaagatgg gtataagtca tttatgttca
       61 ctctccttgt atgctttagc gggtattaca atttgagtgt aacataaatg gcttttttat
      121 ttgtctcgct taattataca aacggcgatc taaaaaaatt gtatctccag gatgcaaccc
      181 attttcttta agaaattcct tttaaattgt taatactact gagtgcccca cttctctgaa
      241 ttttctttaa cttctccctc ccctttttta tttgtatata cattcatata cgcttgttaa
      301 tatcaaatca accgtagtct ctcttatgtc taattatata gaaagattgt tctttctata
      361 taatttagac aatttaaaaa attaagattg cctccttctg tttcctttcc tattcatgta
      421 taccatttat tttaaattat taaatctata cctatttatc tgcttttttg aaataaatta
      481 ataaatttca aagtatacca attgacaaaa cactctataa ttggtatagt ccaattatag
      541 agatactcct ctcccctact tatcgaaagg atgaataaca tgaaaaatac agaaatatat
      601 caaaaaatag atacaatcat acttcatatg cccgattata taaaagattt tgttcaagat
      661 cgtgaggata aagatcaatc acctcgaact actttagaat atctaaaaaa ttataagctc
      721 ttttatgaat ggcttctgag tgagtctatc gttcccgata cttcaatcac ctcgataaga
      781 cagttaactg cctatgatct aaacttgtac aaatctcatt tgaaacgtcg cacaaaggaa
      841 aatgtaaaaa aagagacaac aaaaactaag ctcaaagata ataataactt aggtctatct
      901 acttctacta tcaatagaaa tatcacagca ttaaaggttc tatttaaata tctttcgaaa
      961 agttccaata atcctttagg aaaaccatac ttagaaaata atcctatgga tcaagtagca
     1021 actatcacag ataaaactac gttagctgcc cgtgcaaacg caatcgagaa aaaattattt
     1081 ctagacgaag atacacaaaa ttatctagat tatattgcca atgaatataa aaaaactttg
     1141 agcaaacgag ctttgatcta ttatcaacga gatgtagaaa gagacctggc gatcaatgca
     1201 ttgattttag gatctggatt aagactctcc gaggttgtaa atattaattt agaggaccta
     1261 tctttagaaa agaataatgt ggtagtaact agaaaaggaa ataagagaga cgcagtaaat
     1321 atagcagcat ttgcaatgga atatttagct aattatctag ctattcggaa agaacgatac
     1381 aaagtaacag aaaacgaaaa agctttattt ctagcaattt atcaaggaga agccaagcgt
     1441 atatccggta ttgcaatcga acggatggta gcaaaatatt caaaaggatt cagagtccaa
     1501 gtcagtccac ataaattacg tcatactttg gctactagac tctatcaaca gacaaattca
     1561 ttggtattaa ctgcccaaca attgggacat acaagtacaa atacaacaac tttatatact
     1621 catatagaca atgcagctac aattgatgct ttgaacgctt tgtaaatgta gtaaaaaata
     1681 gtataataat gaagcctgtc tctaaaatta gataaaagcc caactttaaa ggcaagcttc
     1741 attatcattt ttata
//
LOCUS       DAPBBR010000135         1715 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPBBR010000135 DAPBBR010000000
VERSION     DAPBBR010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.146"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            476..727
                     /locus_tag="RD488_002783"
     CDS             476..727
                     /locus_tag="RD488_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658773.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
     gene            761..1039
                     /locus_tag="RD488_002784"
     CDS             761..1039
                     /locus_tag="RD488_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658774.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
BASE COUNT          607 a          232 c          327 g          549 t
ORIGIN      
        1 atacaaataa ttggtttatt ctggcaggcg taatgctttt ttctagtttc tatttattta
       61 gtaatgctct attagcacag cgagggaaat ataagtttaa aatattagat tagatattat
      121 ttttagaggg gataaatata aaatgaaaag aggttattta taatggaaaa agtattacca
      181 attaagagct actgtattcc aaggcttttc atcatagaat ttcaaaagta aagacatgtg
      241 tttcacaaat agtgtctatc ctggctaaat aattcttcca ctatctgctt taatttcagt
      301 agacttttcg gcaagttatt tgctaatgag atgaatagag attacaactc gcctataacc
      361 gcttaaaaca agctttttta aagtatagtt agcaagtcgt attcatatgt tcaaagagga
      421 gggcttatga actttgaatt cattccgtgt gaacagaaca gtagggggaa gtaaaatgaa
      481 agaaaagcct ataaataaat ggtcattgta taaaaattca atgtttggag ttgttatctt
      541 tggtgtttgt gctggattat tccttttcat attattacaa acggtgactc ttttctcttc
      601 taatcctact tatggatgga gagacagtat agccttaggg atgtttgcgg gaggatatgg
      661 attcttattg ttgttctcaa ttctcacact aagtccaatc catggactca ttcaactttg
      721 gaagtaagaa cgagccttaa acttttcgtt ctcggaagaa atggaaaaac acaacataac
      781 aggcagtatg tatgtggatg atcaatggtt tatcagcact gatgaggtaa aaatagctgc
      841 cattaggaga gattacctgc agaaaattca taaaataaaa gatcctaatg ggaaaaaggc
      901 aaggttaatt ataactttga taacatctaa tggtaagaag ttaaaacttg caggatcata
      961 tgataatgtt aaaaagttcg aacattggta tctgcaaaaa gacagcatta gtcttaataa
     1021 acaatttgaa aaaaattaat caaagtcatc ggcaacacga ataatttgac atcttgatat
     1081 tgtgatataa gcaaaaacgg catttctgag accgaacagc ataaaaaatt taaatgttgg
     1141 aatttatata agcaaaaccc aagaagctag atgcgataga gcatttaatt tcttggggtt
     1201 ttgcttggga atcagcatat caattaaaat gatcatctcg gtatttcaaa agtgggtacg
     1261 attacaaata gttggagcaa aatagtgggt aaaattacca ttccagtgtc tgtcttgcct
     1321 ctttttcgtc aatcacaaat agacgagatt cataggaaaa atcgatacag ggtatgattt
     1381 caatgatatt atgaccaatt acaaaataga ttgataaagc attttttgca tttttataat
     1441 agtttattga taataatgta tgagatacag tataatgatt taaaaggtaa cgtgttgtga
     1501 ccgaattaaa tgaattaatg cctatttttt atattcctta gtggacaaaa atggagacag
     1561 tgaagttagg agcattgtat cctttgttgc gtagttcaaa aaagtaagcg atttctataa
     1621 tggtcagggt aaacggtgag ggctgtccac gtaaatccta ctattgaaat cacaatgatc
     1681 ggacattcaa aaggtggtgc tgaagcagca aattc
//
LOCUS       DAPBBR010000136         1652 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPBBR010000136 DAPBBR010000000
VERSION     DAPBBR010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.147"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            96..506
                     /gene="spx"
                     /locus_tag="RD488_002785"
     CDS             96..506
                     /gene="spx"
                     /locus_tag="RD488_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7658775.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     TLAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            520..876
                     /locus_tag="RD488_002786"
     CDS             520..876
                     /locus_tag="RD488_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7658776.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVEKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            1547..>1652
                     /locus_tag="RD488_002787"
     rRNA            1547..>1652
                     /locus_tag="RD488_002787"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          591 a          256 c          311 g          494 t
ORIGIN      
        1 ttattttgat ttttttttat attttattag ctaataattg gtattttaaa agaaattact
       61 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
      121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagacc ttggcagcga
      241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
      361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
      661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      721 attgcgattg acctttcctg tgtagaaaaa aaacaactga tttttttatg cacacaacat
      781 accaacctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      901 ctgagcattc catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
     1021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1141 ttgttgacat gttagaaatg acatgataag ataactgagt cgttaaaaaa ggaccgcttg
     1201 cgaagcttga ttctatcgaa aaaacttcaa aaaagttctt gacaaataac aaacgacaag
     1261 ttatgataaa tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa
     1321 gagttgacaa ttacttgtct ctctgatatg atataaaagt tgctgcggca gccaaaaacg
     1381 aatcgggaaa cactcctgat gaagtagacc tttgaaaaat gaacaaagta agacaaacca
     1441 aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca tttttaacaa gcaagcaata
     1501 tgctagcaaa caaattgagc ttaacaatcg caaggttgtt cgaacttttt atgagagttt
     1561 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg aacgcttctt
     1621 tttccaccgg agcttgctcc accggaaaaa ga
//
LOCUS       DAPBBR010000137         1605 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPBBR010000137 DAPBBR010000000
VERSION     DAPBBR010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.148"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(81..635)
                     /locus_tag="RD488_002788"
     CDS             complement(81..635)
                     /locus_tag="RD488_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7658777.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1378..>1605
                     /locus_tag="RD488_002789"
     CDS             1378..>1605
                     /locus_tag="RD488_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HDT7658778.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIKIGYIASEKDRIIDYLADKDYDLKLLSVH"
BASE COUNT          550 a          280 c          187 g          588 t
ORIGIN      
        1 cttccgaaaa ttcagttatc ttcattaatc tcaccttcta agttttcatt atacacaaaa
       61 aatatatcct aatatctcaa ttagcctccc aatttaaaac cacgtaacga tgcccctatt
      121 tcatcttcag ttataccaat gtaccttttt gtaattgctt gcgagctatg attaaaaata
      181 aacattaagg tagcaatgtc tctagttttc ttgtagtagt gatacccaaa agtttttctt
      241 aatgtatgtg ttcctatatc atctcttcct aatttttctg ctatatctgc atatatctga
      301 tagacacgat cccttgttat atgtcgacct tgttgccgac ttggaaataa ccaatcattt
      361 tcttctttac cttcagtata taataaaatc tcttctctca aattatctat aaaaatcggt
      421 tttcgcttac ctgttttatg ttcaacaata ataggcttac ttttacctcg tatgtctcca
      481 acttttaatc ctataatatc tgacatacgt aacccattat tgattccaaa caaaaataaa
      541 aaactatctc tttctggatt acttgttctt cttagccaaa actgaaaatc ttgtatctct
      601 tcatttgtcc ttaacggttg tacattatag ctcactattg tttcccttct taaaaatatt
      661 ctgagttcat gattatatat atattttacc ataatcatga acttatatat atactctgtt
      721 aaaagtgaag aaaatcaagg ggtttagttt atgattttat atcatttcag taactcagaa
      781 tattccgact tttttgtaca aaaaaattaa ccttacttat atgaagattc taacctctta
      841 tttaaatttt agacgggcaa ttatccgtag aagttcttag aatagctaat ttacataatt
      901 aaattatatg aaatttaagt ttgaacaata tactaagaac tccccttact ataaagtgaa
      961 ataaattagc atatgaataa ccgtgctacc aagcttttca ttaataaaat atttttattg
     1021 atattttata actttacgca agatcataat tttgtctgtg tagatatttc gttatatcac
     1081 taaagataat aagatttaat gacctcatta atattgtttg ctagatccaa actcttatta
     1141 aactttcctt gctataaaac ccaaacatag taataaaaga ataacttatt acctttaaat
     1201 tatactacca acaaatggta gtatattatt aatttatata atatgaaacc taaaatatag
     1261 tagtataccc gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta
     1321 aatcaacaaa aaaacgcata tagtagtctc aaatctccca agaaatgagg actacatatg
     1381 cgttcatcaa aatatactga acattttgac ttagccaatc ctgttactaa agtcgatgat
     1441 atccccgatt atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat
     1501 cgtgttttaa aaggcatcaa aatcggttac atcgcttctg aaaaggatcg gatcatcgac
     1561 tatttagccg ataaagatta cgatttaaaa ttactcagtg tgcat
//
LOCUS       DAPBBR010000138         1571 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPBBR010000138 DAPBBR010000000
VERSION     DAPBBR010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.149"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            55..>1571
                     /locus_tag="RD488_002790"
     CDS             55..>1571
                     /locus_tag="RD488_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7658779.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWN"
BASE COUNT          532 a          282 c          327 g          430 t
ORIGIN      
        1 gtttcttgtg gtattctgta acaaaatcag ttcgattcaa ggtggtgaaa aattttggaa
       61 actacagata cgttgcttca gttgcttcaa gaagcccata aaaccaatca agcacaacaa
      121 caaaccattc agaatcttac aactgaaatc caactattga atgaaaaggt caattattta
      181 accaacaaat tatttggacg ctctaaagag actctctttg aggaaacgaa tgggcaattg
      241 aatcttttta gtgatgaaga aatttctgta agtgttccag aagcagctgc caccattatt
      301 ccagtaaaag gacatcaacg agttgtagga acgaaagcag acaaaatcaa acacttacct
      361 ataacagaga aagaacatct ccttcctttg gaagaacaat tttgtgaaca ttgcggttca
      421 cagatgaaag atatcggacg gacaaaagta cgagaagaaa ttcgtttcca tcaggctatg
      481 ttggattgtc tcacccatta tcaacatacc tattgttgta aaagctgcga aaaagaagga
      541 ctttcttctt ttaaaaaagc gatcgttcct aaacctttga tttctaatag cttaggttcc
      601 aatagtttag tggcggaaac gatccggatg aaatttggtc agaaagttcc tgcctatcgg
      661 caagagaact attggaaaca aacacatggg ttggatattt cgagagataa tatcaccaat
      721 tggcatatta aagcagtgca aaacgcgtta gaccctttag gagaacgatt aagagtctat
      781 cttaatcaag aagagattct acacggggat gaaacaagtt atcgtgtgat tgaaagtgcc
      841 aaaacagata cctattactg gcagttttgt acaggaaaag acagtcagca tcccatcgtt
      901 tattatcacc acgacgaaag tcgtgctgga gatgttccga aaacttttct caaggagttt
      961 acagggtatt tacactgtga cggctatagc gggtataatg ccgtggaaag tgtacgactt
     1021 gtctattgtt tcgcgcatgt tcggcggaaa tttttcgaag caattccaaa aggaaagaaa
     1081 aacacggata ttcccgcagc tcaagcagtc aaacaattgg ataaatggtt tgtcctagaa
     1141 aagaaatgga aagacttttc tcctgagaag cgattaagct gtcggcaaca agaactgcgt
     1201 ccattattta ttgcttttta tgagtggatg gcaacgatag atcctgttgc aaaatccaag
     1261 ttggatgcag ccgttcaata tgcgtgtaaa ctacgaagtg gttttgaacc tatttttgaa
     1321 gatggtcgtt tagaactcac aaataatcgt gcggagcgaa atatcaaaga gctggtgata
     1381 ggacggaaaa attggttgca ttccacaagt cttgaaggag cacgaacttc aggaatcatt
     1441 ctgagtgtat ataaaacagc agaacttaac ggattgaatc ctgtaaagta tctagagttt
     1501 ctatttgata agataccaaa tcttcccgta ctttcagcag aaactttaga tcaactgttg
     1561 ccttggaaca a
//
LOCUS       DAPBBR010000139         1567 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPBBR010000139 DAPBBR010000000
VERSION     DAPBBR010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.150"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            174..791
                     /locus_tag="RD488_002791"
     CDS             174..791
                     /locus_tag="RD488_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658780.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            832..1131
                     /locus_tag="RD488_002792"
     CDS             832..1131
                     /locus_tag="RD488_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HDT7658781.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1165..1332
                     /locus_tag="RD488_002793"
     CDS             1165..1332
                     /locus_tag="RD488_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7658782.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1377..>1567)
                     /locus_tag="RD488_002794"
     CDS             complement(1377..>1567)
                     /locus_tag="RD488_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658783.1"
                     /translation="QKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAK
                     ENGISRPTIYKIKKANDL"
BASE COUNT          520 a          247 c          325 g          475 t
ORIGIN      
        1 aatataatca tgcgggagtg taaacttact gtttcaaaaa gtatactttt tgacatgcct
       61 tgattttctt tgtttatgta tggcataata accacataat acaatttgaa acgtttctga
      121 tttaatctga ttgttttgaa acaattttag tgaaaaaagg gtagataaaa acgatgagaa
      181 aattttttta tatccgggtc agtagttatg atcaatcgat cgaacgacaa ctgatttccg
      241 cgaaggaatt aggaatccct gaagaatata tatttgtaga aaaagccagc ggcaaagatt
      301 ttaaacgccc tgaatatcaa ttaatgaaac ggatgtttcg aaaaggagat ttactctatc
      361 tacaatcatt agatagacta ggcagaaata aacaaatgat tttagaagaa tggcgagaat
      421 taactaagga aaagcagatt gatatttctg tgttagacat gcctctgtta gatactgcta
      481 gttacaagca actagatggg ttagagacgc ttatctctga cttaattctg caattactca
      541 gctatatggc cgaagacgag cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag
      601 ctgcgaaaca aaagggtgta aaattcggca gaaagaaaat tgctttacct cctgaatttc
      661 ctgcgatcta ttctgactgg aaagcaggaa agataactgc agtctatgct atggatcaat
      721 tgggcatgaa acgaaatacc ttttatcgac gggtgaaaga atatgaacat accttgcacc
      781 acttttcttg atagatataa cagctattag acgggaaggg agagtttgaa aatggactta
      841 acgaatcaaa gggtcgtttt tactggaacg ctgcagcaaa tgacacgaac ccaagccatc
      901 ggtttggttc actctttaaa cggccattgt caatcaagtg ttacttcaaa aacaaatttc
      961 ctggtttgtg gtcagtattc taagtcgttg tttgatgatt ctctctatac aaaaaaggaa
     1021 caaaccgcgc gggacttgat tgcgttaggt catgagatta ccattttatc agaagtcgaa
     1081 ttttatgcgt taattagtca acagttgaaa gaatggcaac ggtatttata atcgttagta
     1141 aaatttacaa ggaggaaaat ttttatgaag cgaaaatctt atgatcgttg gggcattgaa
     1201 ataactagtt ttaatcgaaa tattgctttt cacgtggagt gtgactgtgg ggaattagca
     1261 aaaagtgttt atcaaaaaaa ttacttttac tgtcctaaat gccatcgccg atacggggta
     1321 catggaacat agaaacgaaa tagtgcggta gaaaagcgaa tgaatgtagt atatttctac
     1381 aaatcattcg ctttctttat tttataaata gttggtcgag agatcccgtt ttcttttgca
     1441 atctctgcaa ctggaatgcc ttgctttaac atgtccacca cggttttaaa aactaagcgt
     1501 ttttgcggat ctgttgagtt aatagaatac tcgattggtc gtcccttata tcggccggct
     1561 ttttgag
//
LOCUS       DAPBBR010000140         1558 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPBBR010000140 DAPBBR010000000
VERSION     DAPBBR010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.151"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            44..103
                     /gene="ermCL"
                     /locus_tag="RD488_002795"
     CDS             44..103
                     /gene="ermCL"
                     /locus_tag="RD488_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HDT7658784.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            152..886
                     /locus_tag="RD488_002796"
     CDS             152..886
                     /locus_tag="RD488_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HDT7658785.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          584 a          245 c          211 g          518 t
ORIGIN      
        1 tgtgctataa ttattctaat ttcataaaaa ggagaattaa tatatgggca tttttagtat
       61 ttttgtaatc aacacagttc attatcaacc aaacaaaaaa taagtggtta taatggattg
      121 ttaatataaa acctcatagg agtgggttat aatgaacaaa aaaaatataa aagatagtca
      181 aaactttatt acttcaaagc atcatataaa tgaaattttg agaaatgtac atttaaatac
      241 aaatgataat attattgaga ttggttcagg gaaaggtcat ttcacgtttg aattagctaa
      301 aaggtgtaat tatgtaaccg ccattgaaat agatcctaaa ttatgtagga taactaaaaa
      361 caaacttatt gaatatgaga acttccaggt tatcaataaa gatattttac aatttaagtt
      421 tcctaaaaat aagtcatata agatatatgg aaatataccc tacaatataa gtacagatat
      481 aattcgaaaa attgtttttg aaagcacagc tacagaaagt tatttaatag tggaatatgg
      541 atttgctaaa aggttgctaa atacaaatcg ttcactagca ctatttttaa tgacagaagt
      601 tgatatatcc atattaagta aaatccctag agaatacttt catccaaaac ctagagttaa
      661 tagctcgtta attgtattaa aaagacaccc ttcaaaaata tcactcaaag atagaaaaca
      721 atatgaaaat tttgttatga aatgggttaa caaagaatac ataaaactat tttccaaaaa
      781 ccaattttat caagccttaa aatatgcaag aattgacgat ttaaacaata ttagctttga
      841 acaattcttg tctcttttca atagctataa attatttaat agataagtta aggggtgcat
      901 aaactgcatc ccttaactta tcttattttg cttaaacaat cttggcccgt aaactgcata
      961 actcatatgt aaatcgctcc tttttaggtg gcacaaatgt gaggcatttt cactatttcc
     1021 ggcaattact tccatgtaaa gtataaccca ctatactttg caagcaaagt gtgggctcgc
     1081 cgaggggtct tgcagacggc tctttcggct cttttgagcc gagtatcagc gcacccttat
     1141 ggtgcaatta gctgatacct gtttgacgat ttgctgccct accttttcgg taggtatgca
     1201 aacctcaaac caaaataaaa acccccttcg acttcgtcag ggggttttta tttatataaa
     1261 tctccgtaaa taatcgcgat ttaataacat cttcaatttt atttttttgc gtattttaga
     1321 aatgttttca ctaaaaaata tattatacaa aaaatacagt aatcgattat aattctttgc
     1381 cagttaaata tcatatcgtt attaaaatat cggaaaaaaa tatcaacaac aataaatgca
     1441 aaagaagacc ataaaaattg tttattactc atacatactc tccatttcta tcatttttaa
     1501 atttaccagt catctctcaa aaatctccta gctatttttc ttttttaacc acataccg
//
LOCUS       DAPBBR010000141         1456 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPBBR010000141 DAPBBR010000000
VERSION     DAPBBR010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.152"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            108..1040
                     /locus_tag="RD488_002797"
     CDS             108..1040
                     /locus_tag="RD488_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HDT7658786.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="RD488_002798"
     CDS             1112..>1456
                     /locus_tag="RD488_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658787.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAPBBR010000142         1437 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPBBR010000142 DAPBBR010000000
VERSION     DAPBBR010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.153"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            135..>1437
                     /locus_tag="RD488_002799"
     CDS             135..>1437
                     /locus_tag="RD488_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HDT7658788.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRR"
BASE COUNT          454 a          294 c          269 g          420 t
ORIGIN      
        1 attaaaacca tgtgaaactg cctcacggca gcttacaatt actttttcat cttcacccgt
       61 taagtgatga aaaaagaacc cctttctgct atggttaaag tgactaaacc aaccaaaaga
      121 aaggagttct tttcatgact agcttacaca aaaaccaagt aaaattcaat tcaaatatca
      181 ctatttctca tacaggtggt caattatcga gtgattcggg tctcgtccta gtgaaagagc
      241 tgatgaacat ctttggtttt tctgaactgg ctaagcaaca cattcacatt gaagacgaac
      301 gagcgtattt tactcatgac aacttatcca tacttgagca gttcattatg caattaattg
      361 ctggttactc agctgattct gcagctaatc tcctgagaca agatcctgtg tttaaagctg
      421 ttttagatag gaaagaactc gcttctcaat cttcactttc ccgattttta gatcgactat
      481 ctgaggagaa tatccatgaa cttcaagctt tgaaccaaga acttatcgat aaagcacgcc
      541 tcatccgtaa tgatacggaa ttaatcattg atttagattc gacccattca gatacatttg
      601 gtcaccaaga acaaacgaat tataatacac actaccaaac ctatggttac catccattgg
      661 tagcttttga cggattgact ggtgacttct taaaagctga actacgttca ggaaatcaat
      721 atacatcaaa aggcgtaaag gagtttctca cacctttatt agagcactat aatcactctc
      781 taccaaacac tgacatcttg gttcgtggag acagcgggtt cgctacacct ggtgtgtatg
      841 attcgtgtga atcaaaaaag agtcattatg ttattcgact gaagaataat cgtagactag
      901 gtcaaatagc tgagaaatca gtactttatg gcgataatca aaagtgggaa gaacgagaag
      961 ttcagtactt ctcgaccact tatcaagcac aatcctggtc acaaagtcgt cgcgtgtgta
     1021 tacgctcaac acgtgaagcg ggcgaactac tctttcgaca tgaatttatc gtgacgaatc
     1081 tatcagaaaa tgtttctcct gataccatct tttctatcta tgccaaacgt ggcacaatgg
     1141 agaacttcat taaagaagcg aaagctggct tttactttga caaaacagac agtcctcgct
     1201 ttttggagaa tcatgtccga atgatgctca gcttgatagc ttacaactta gtcaacttct
     1261 taagaacgat tggctttgaa gaagtccaaa agggaatgac cattcattct attcgattga
     1321 agtttctgaa agttgctggg aaattagtcc aaacgggtag acgagtctat ctcaaattat
     1381 ctagttatca tgtgtatcag aatgaattct acagggtctt tgctcgcctg aggcgag
//
LOCUS       DAPBBR010000143         1424 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPBBR010000143 DAPBBR010000000
VERSION     DAPBBR010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.154"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(150..1337)
                     /locus_tag="RD488_002800"
     CDS             complement(150..1337)
                     /locus_tag="RD488_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HDT7658789.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAPBBR010000144         1413 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPBBR010000144 DAPBBR010000000
VERSION     DAPBBR010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.155"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            90..1382
                     /locus_tag="RD488_002801"
     CDS             90..1382
                     /locus_tag="RD488_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7658790.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          458 a          289 c          258 g          408 t
ORIGIN      
        1 atctttttta ttttccaaaa catatagaaa agacaccttg aaatccttta gaattaattt
       61 ggcgaaccaa cccaaaagga ggaatcaaga tgtcttacac tcaccttatc aaagaaacat
      121 tagatattct agacttatca gttactttta acgaaaattg tctcacaaaa gaaaaataca
      181 aagggcaaat ctgtcatatt tatcgtggaa acttgattta tacagcccaa gaatgcatcc
      241 actgtaaaca ccagattgct tcagatattg tgcgttgggg tacaacaacc gtccggttgt
      301 taatgaacga tgtttctgaa tgccgtacct acctcgaatt gaaaaagcaa cgcttcaaat
      361 gcaaagcttg tcagcggacc tttgtcgcag atacttctgt tgcgaaaaaa cactgtttca
      421 tcagtgagaa agtccgctgg tctgtcgtga ctcgtctgaa aaaaaatacc tcaatgacag
      481 agatcgccgc tcagaaaaat ctatcggtct cttctgttta ccgtattatg aagcgatttt
      541 atcgtccgtt gaatcctttt cggacaccgt tacctaaggt actttgtttt gatgaattca
      601 aatcagttcg gggtgtttca ggtgctatga gtttcatcat gatggatgga caaacacagc
      661 gcttgttgga cattgtcgag aaccgacaac tgcctttttt aaaacgttat tttagtcatt
      721 tttcacgaga aattcgtgaa gcggtcgaat ggatcgtgat tgatatgtac gctccttatg
      781 tatcgctcgt taaaaagctg tttccaaaag cacagctgat cattgaccgg tttcacatcg
      841 tccaacatat tggtcgtacc tttcgcaatc atcgaatcaa agaaacgaac caactattaa
      901 aaagcaaaga acaaaaacac tatcaattag gtaagcaatt aaaaagatac tggaaacttc
      961 ttcaaaaaga tgaacgcaag cttgattata ctcgacgcct ttggcgacct ggcttcaaag
     1021 ctcatttaac agagaccgat attgtggatc gcttactgaa agggagccct gctttgcgtg
     1081 taggctatca gttatatcaa gactttcttt acgctgtaaa ggaacgagac tacgtatcgt
     1141 ttgaagaact acttaccaat aatatcatgc ttcccgaagg ctatcagacg accttgagaa
     1201 cgttccagaa atttctgcca caaatcaaaa atgctttaca acaaagttat tcaaatggcc
     1261 cacttgaatg tctgaacaac catatcaaag tgttaaaacg aaatgcatat ggctttcgta
     1321 gcttttataa tttcaaattg cgcatcatga ttcgtcatgg caacgcattg attttcaact
     1381 aaaaaagatc aagaggaact gatccacttg atc
//
LOCUS       DAPBBR010000145         1374 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPBBR010000145 DAPBBR010000000
VERSION     DAPBBR010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.156"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            33..1372
                     /locus_tag="RD488_002802"
     CDS             join(33..474,474..1372)
                     /locus_tag="RD488_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HDT7658791.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          576 a          177 c          239 g          382 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DAPBBR010000146         1352 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPBBR010000146 DAPBBR010000000
VERSION     DAPBBR010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.157"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            82..>1352
                     /locus_tag="RD488_002803"
     CDS             82..>1352
                     /locus_tag="RD488_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HDT7658792.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFL"
BASE COUNT          459 a          260 c          257 g          376 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg at
//
LOCUS       DAPBBR010000147         1292 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPBBR010000147 DAPBBR010000000
VERSION     DAPBBR010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.158"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            141..398
                     /locus_tag="RD488_002804"
     CDS             141..398
                     /locus_tag="RD488_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658793.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="RD488_002805"
     CDS             complement(630..1061)
                     /locus_tag="RD488_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HDT7658794.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          489 a          167 c          161 g          475 t
ORIGIN      
        1 ttctgtccac gttcatatta ctccaaagtt ttcctcattc caaaagaaaa gcacagaata
       61 cacaaagaag cgtttttatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaaat tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 acaaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatccc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca cacataaaaa taaaaaacat
     1141 ttgtatttta tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct
     1201 atttgtttac ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga
     1261 atctaaataa taaattttta tgtaccgccc ct
//
LOCUS       DAPBBR010000148         1236 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPBBR010000148 DAPBBR010000000
VERSION     DAPBBR010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.159"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            2..>1236
                     /locus_tag="RD488_002806"
     rRNA            2..>1236
                     /locus_tag="RD488_002806"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          373 a          245 c          361 g          257 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaattgagaa tgatggaggt agagcactgt
      901 ttggactagg ggcccatctc gggttaccga attcagataa actccgaatg ccattcattc
      961 atatccggga gtcagactgt gagtgataag atccatagtc gaaagggaaa cagcccagac
     1021 caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg atgtggggtt gcacagacaa
     1081 ctaggatgtt ggcttagaag cagccaccat ttaaagagtg cgtaatagct cactagtcga
     1141 gtgaccctgc gccgaaaatg taccggggct aaacatatta ccgaagctgt ggagtacacc
     1201 tttaggtgta ttggtaggag agcgttctaa gggcgt
//
LOCUS       DAPBBR010000149         1216 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPBBR010000149 DAPBBR010000000
VERSION     DAPBBR010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.160"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..707)
                     /locus_tag="RD488_002807"
     CDS             complement(<1..707)
                     /locus_tag="RD488_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7658795.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNA"
     gene            complement(993..1199)
                     /locus_tag="RD488_002808"
     CDS             complement(993..1199)
                     /locus_tag="RD488_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7658796.1"
                     /translation="MNLIYDEIAIDPYKGEQKTGDLSGIWSSGFKYAGTTYRVAYEII
                     ENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT          388 a          241 c          165 g          422 t
ORIGIN      
        1 gcatttttga gtacaacatt tttaatcaaa tgttccccat aaatctcttg ggcttgttta
       61 tacatttcct gatctactgc gtcaccgctt tccaacatga aaggaataac accagcaaca
      121 tataaatttg tatcaaattc tttcacaaaa aagtccatat actcaagata ttgcatcgca
      181 tttctcatcg attttacttg ggtctgtaag acgacgattg cccagtccgc aatgtacatc
      241 gcggatttac tatatacaga aatagaaggt gggacatcta aatagatgac gtcaaactca
      301 tcaaataatg gttctagctt ttctttcata tatttgaatt gggacaatga atcattatat
      361 tggtctttga tccaatcatc atacatttca aaggacatgt ctgctggaag tatatagagg
      421 ttattgatta ctttatagac agcctcttta ggtggaagat tgtttatcaa cacgtcagtc
      481 acagtatttt cgtaaacaat cggttcacct tctccgcctc cttcttcgtt agtgaagttc
      541 atatgcgtta agttcatcac atcagaagta tttccttgca tatccaagtc aattatcaag
      601 gttctttttc cttcattaac tgctgattca aaccctaaca tttgcgcgca cgtactttta
      661 cctacgccac ctttaaaatt accgattaca tattttttcg ctaccacgtt cctacctctt
      721 ttcttttagc aatattcatt tgatactatt ataacatatt tatttttagt tactaccaaa
      781 aaaaagatat atatgtacta ccttataatt aataagtaaa aggtagtaca taaataagga
      841 aaagctgaaa tatattgatt tatagctttc ctcaaagtaa tgacgttatt taatttatcg
      901 agaagcagag aatactcgcg actttagtca tgtagatgaa tcagatcttc gataaaaaag
      961 aagccgtcct tcttaagaac gacaacaaat cactagatta attttttcaa ctgttcataa
     1021 aagttttcat gcgttccaca taacaatact ggaataacct tgttttctat aatctcgtaa
     1081 gctactctat atgttgtgcc cgcatatttg aacccactag accaaatacc tgataaatcc
     1141 ccagtttttt gttcaccctt atatggatca atcgcaatct catcataaat taaattcaaa
     1201 aatttttctt tcaatg
//
LOCUS       DAPBBR010000150         1193 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPBBR010000150 DAPBBR010000000
VERSION     DAPBBR010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.161"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1076
                     /locus_tag="RD488_002809"
     CDS             <1..1076
                     /locus_tag="RD488_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7658797.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAPBBR010000151         1173 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPBBR010000151 DAPBBR010000000
VERSION     DAPBBR010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.162"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..128)
                     /locus_tag="RD488_002810"
     CDS             complement(<1..128)
                     /locus_tag="RD488_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658798.1"
                     /translation="MIQELNRLMTYIEARLTKEISLAEAAKTMGLSEYHLKRTFSF"
     gene            complement(497..>1173)
                     /locus_tag="RD488_002811"
     CDS             complement(497..>1173)
                     /locus_tag="RD488_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7658799.1"
                     /translation="IVIPPAIFFYYSTLSDSRFKTLQQNHPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVEPSEPTEPSEPTEPSEPTEPSEPTEPTEPTEPTEPTEPGKPTEP
                     SKPTEPNKPTEPSKPTEPNKPTVPNKPVDTNPIENPVNTDTGVVIVAVEDSKPIIQLA
                     DGTTKKVEAKEIGANVQKDGTVTVKGSDGKMKVLPKTGDTENIALSVLGSVMVLGSAF
                     IFKKRI"
BASE COUNT          279 a          230 c          231 g          433 t
ORIGIN      
        1 ataaaagaga acgtacgctt taaatggtat tcagataatc ccatcgtttt agcagcctct
       61 gccagtgaaa tctcttttgt taatcgtgct tcgatatacg tcatcaaccg attcaactct
      121 tgaatcattt cttccacctc acctatgtac ttattctata taagattccg ttattggact
      181 tgataaatgc tagactaata ttatcggttg catcctttgg aatgacaaat catttaaact
      241 tgattttcat gcacgtactc ctaaaaaaat aatgactttt tccgactcat ttgtcttcaa
      301 caactattaa acgtctctgt acgcacaatt gctaacagaa tactcgatag gttctgttgt
      361 tattggtgtt gcctagaacg attctaagcg cttgtttaat tttaaggtat acattcccct
      421 tcaaaacgtc ctagaatgat tcaataaaag catggctgct agtgaaactt gcgaccacgc
      481 ttttataaat acttaattag attcgctttt taaaaatgaa tgctgatcct aataccatta
      541 ctgaccctag gacagacaat gcaatatttt ctgtgtctcc tgtttttggt aaaactttca
      601 tttttccgtc tgaaccttta accgttactg ttccgtcttt ttgaacgttt gcaccaattt
      661 ctttagcttc aacttttttt gttgttccgt ctgctaattg aataatcggt ttactatctt
      721 caactgcaac aatcacaacg cctgtatctg tattaactgg gttttcaatt gggtttgtgt
      781 ctactggttt gtttggtact gttggtttgt ttggctctgt tggtttactt ggttctgtcg
      841 gcttgtttgg ctctgttggt ttacttggtt ctgtcggctt gcctggttcc gttggttccg
      901 ttggttccgt tggctccgtt ggttctgttg gttcgcttgg ctctgttggt tcgcttggtt
      961 ctgttggttc gcttggctct gttggttcgc ttggctcgac tggatcaact ggatcaactg
     1021 gatcgactgg atcgactgga tcaactggat cgactggatc aactggatca actggatcga
     1081 ctggatcaac tggatggttc tgttgcaaag ttttaaatct actatcagat aaggtagaat
     1141 aatagaaaaa gatagcagga ggaatgacga tga
//
LOCUS       DAPBBR010000152         1147 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPBBR010000152 DAPBBR010000000
VERSION     DAPBBR010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.163"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>1147
                     /locus_tag="RD488_002812"
     rRNA            <1..>1147
                     /locus_tag="RD488_002812"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          299 a          261 c          355 g          232 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggt
//
LOCUS       DAPBBR010000153         1080 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPBBR010000153 DAPBBR010000000
VERSION     DAPBBR010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.164"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(144..1080)
                     /locus_tag="RD488_002813"
                     /pseudo
     CDS             complement(144..1080)
                     /locus_tag="RD488_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          315 a          210 c          213 g          342 t
ORIGIN      
        1 aaaacgccaa acattcccga ttctattcta taggtcgggt tatttgacgt acaggtactg
       61 ttctatgggg cgcttacgat gttttaaaag atgtgtttgg tctcttattt gaaaaaatgc
      121 ttcaaggaga attgaataac catttagggt atgacgccca ttctaaagag ccaaagaaac
      181 atgacaatcg acgaaacggt tatggcaata agacgcttaa aacgagcttt ggtaaagtaa
      241 acattgatgt tcccagagac cgggaggctt cttttgaacc tgagttgatt cctaatagaa
      301 aacgagatgt ctccgacatc gcagactgta gacaaaagct gttccaaact cgtaactcga
      361 gcttggaaca gctttttatc tacttcgttt cgaatttttg aacaaaaaaa taaaggctcc
      421 ttgcctttcc atagccaggt ggctaatttc tttaaattca ttgcagcaaa cactagcatc
      481 gtatgcgtcg cgactttttc caagcctcga tacttggtcc aacgcatccc atgcttttct
      541 tttgcatccg caaatattcg ttcaatcgtt tgtttccgtt ttttgtaaat tgatttattc
      601 agatctgtta ggcgaagatg ttccacttca tccatcagat ctccccaaac atgtctcgtg
      661 atgactcgtt gatgattttt acttttggta cattggttta gcagaggaca gttcacacat
      721 tcttttggat tggatttgta ttctcggtac ctttctcgag taaccgttga aaaagcgagc
      781 atttgatctt gcggacaaat ataacaatca aaatactcgt catagagaaa ctcatttttt
      841 gataatagcc cctttttccc tttgggcctt gaataaggca aacaaggtcg aaggtttaaa
      901 tgagtcaaaa agtgaacaaa cttaggtgtc ttatactcag catcagcgac aacacaattg
      961 atttcaggaa aaagtctctt cgattgtttg atgagctgaa aggcgacttg actgtcatga
     1021 atatttctag gagtgatgat tgtgctaaga ataaatccat tgtcgtcgca ttaagtatgg
//
LOCUS       DAPBBR010000154         1061 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPBBR010000154 DAPBBR010000000
VERSION     DAPBBR010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.165"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(36..992)
                     /locus_tag="RD488_002814"
     CDS             complement(36..992)
                     /locus_tag="RD488_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658800.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAPBBR010000155         1049 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPBBR010000155 DAPBBR010000000
VERSION     DAPBBR010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.166"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..203
                     /locus_tag="RD488_002815"
     CDS             <1..203
                     /locus_tag="RD488_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7658801.1"
                     /translation="IYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQVTDTLVSMFTE"
     gene            256..1038
                     /locus_tag="RD488_002816"
                     /pseudo
     CDS             256..1038
                     /locus_tag="RD488_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
BASE COUNT          438 a          155 c          137 g          319 t
ORIGIN      
        1 ccatttactc aaccaatcta atcgagtctt tcaataagca aattaaaaga tacagccgta
       61 gaaaagagca gtttcaaaat gaagaatcac tagaacgctt tctagtcagc atttttgata
      121 catacaatca aaaatttcta aacagaagcc ataaaggttt tcaacaggta accgatacat
      181 tagtttcaat gtttactgag taactaatta ttttgcagga ggacaattta tttacacaaa
      241 attattgacg ctccccaaga tatgctagat tactactatt ttgaaaaaaa tttatcatat
      301 aattatgtaa tacatttaaa aacttttaca ggaatgattt ttaaattcgc caaccgtcga
      361 tatggattaa aatataatcc cgtaaatggg gtttctttag caagaaaacc taagacaaac
      421 gaagaaataa aaaaagaaaa agatggttat ttatcaaaag aagaagttca aatgattgct
      481 agtaaacaaa aaagttcaca tcaacagtca cgttattctt taattactaa atttttgttt
      541 ttaactggac tacgttatgg tgaattgata tctttgactg aatctgatta tgatggtaat
      601 aaaattacgg tttctggtac ttatgattac gagttaaaaa ttaaaacaac aactaaaaat
      661 acaggttctt atagaaccat tgaattatca agtaatgcta aagaaatcat agatcaatta
      721 attgaagaaa acaaattaat taagaataat aaagataaat acattttcat ctctaaaaat
      781 ggtaacccga tatctattca agcatataat caatctttaa gagcagtatc caaagaatta
      841 aacatagata aaaaagtttc ttctcacatg ttaaggcatt cccacatttc tctacttaca
      901 gaattaggaa tcccattaaa agccattatg gatcgtgtag gacatgaaga ttcaaaaaca
      961 acattaaaga tttatactca tacaactaaa aatatgcaaa atcaactagt agaaaaacta
     1021 ggaaaaatag aaatttaaat tgccccttt
//
LOCUS       DAPBBR010000156         1035 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPBBR010000156 DAPBBR010000000
VERSION     DAPBBR010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.167"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>1035)
                     /locus_tag="RD488_002817"
     rRNA            complement(<1..>1035)
                     /locus_tag="RD488_002817"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAPBBR010000157         1024 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPBBR010000157 DAPBBR010000000
VERSION     DAPBBR010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.169"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            71..>1024
                     /locus_tag="RD488_002818"
     CDS             71..>1024
                     /locus_tag="RD488_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HDT7658802.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYD"
BASE COUNT          376 a          190 c          176 g          282 t
ORIGIN      
        1 tacaaaaaag gaagtccctt ctgtagaata aagttaacga caaccaattc acagaaaaga
       61 ggacttccct atgaatgatt ttactacaga aattgtgcaa actctagtca ctaaaggcga
      121 tttaaatgaa ttattccgtt cgcacttaga aaaagcgata aacacactcc tacggactga
      181 attaacggct tttttagatt acgaaaaata tgatcgcact ggttttaatt caggtaattc
      241 gagaaacggt tcttactttc gatcaatcaa aaccgaatat ggtgaattaa cattggaaat
      301 acctagagat cgtaatggtg agtttaaaca acaaacttta ccagcctaca aaagaacaaa
      361 cgatacattg gaaaccacta ttatccattt attcgaaaaa ggtgttacga tgtctgaaat
      421 tgctgatttg atcgaaaaaa tgtacggtca tcactatact ccacaaacca tgtccaacat
      481 gactaaagtt ctgactgaag aagtaaatgc ctttaaatcc agagccttaa atgataagta
      541 tgtcgctatt tttatggacg ctacttacat tccactaaaa cgtcaaaccg tatccaaaga
      601 agcgatttat attgccattg gtatacgaga agacggcact aaagaagtac tgagttatgc
      661 gattgctcca actgaatcaa catacgtttg gaatgagctg ctacaggata ttaactccag
      721 aggagttcaa gaagtcttgc tttttattac ggacggctta aaaggcatga aagatactat
      781 ccatcaaatt tatcctaaag caaaatatca gcattgttgt atccatgtat ctcgtaacat
      841 cgctcataaa gtacgtgtca aagaccgaaa agaaatctgt gatgacttta aggctgttta
      901 tcaagctaac tcaaaagaag aagcgaatac cttcttatcc ggcatgattg agaaatggaa
      961 gaaaaactat cctaaagtga cgcagtcact catagaaaac caagacttat taacttttta
     1021 tgat
//
LOCUS       DAPBBR010000158          962 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPBBR010000158 DAPBBR010000000
VERSION     DAPBBR010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.170"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            87..160
                     /locus_tag="RD488_002819"
     tRNA            87..160
                     /locus_tag="RD488_002819"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            complement(673..>962)
                     /locus_tag="RD488_002820"
     CDS             complement(673..>962)
                     /locus_tag="RD488_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658803.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          305 a          159 c          162 g          336 t
ORIGIN      
        1 tagtcacact ccaagctatg cgataacagg tttgttgcca cacattctac tggttgattg
       61 tttatggctt tatgtggcaa caaccagtac ccttagctca gttggtcaga gcagacggct
      121 cataaccgtc cggtcgtagg ttcgagtcct acagggtaca ttaacgtagc catttgaatc
      181 gttctgtgtt agaatttttt gaagagtatt atacaagcta aagcttttct tcattgccac
      241 tcaaatgagt ggctttttta tgtatccttt tatggattaa tgaaaggatg tttcacatag
      301 ttatatttct gtatatttga aaagttttac tttgattttt aaatagaaag acatttgggt
      361 taaattgtga gatgataata aagaagagtt taaagcgcac cccaagccac ttccccataa
      421 gtgtgttacg ctttaaactc ttttatattt gaagctatta aaaggcatac catatttttg
      481 aaaaaaagtg agaaaaaagg cttacaattg gagtggtagt taattagtga cttatttttg
      541 attttatagc actgatacta taaaatatag atatcatcat attacacaat cttaatacta
      601 acttaaaaaa tatctccttt cacaagtatg gtgataaaat tcgttccggg ctaccttttt
      661 aggtagccta ctttaatctt tgtatctttc tggatcaacg aaagtatact ttatatagtc
      721 ataacgccga tgatcgctac gtgcgtccgg cacgtcagtc acgatatcaa acaaaaagta
      781 tacatccttc ttcattctag ttttcgcagc aggaattttg aaatagttct tattagaata
      841 gtagagattg attaataagc tatcttcgat tgctaaaaag aaaacttctg aattccatac
      901 tttataaaaa tctttgataa atctattcga agggtcaaat ttaaaccata attgtgtctc
      961 at
//
LOCUS       DAPBBR010000159          935 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPBBR010000159 DAPBBR010000000
VERSION     DAPBBR010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.171"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            81..>935
                     /locus_tag="RD488_002821"
     CDS             81..>935
                     /locus_tag="RD488_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HDT7658804.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKG
                     ITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLESRFES
                     ILLAYSVLL"
BASE COUNT          338 a          167 c          158 g          272 t
ORIGIN      
        1 gaaaatgtct aaacatgttg gtaaatcaac aaaaaaacgc atatagtagt ctcaaaactc
       61 ccaagaaatg aggactacat atgcgttcat caaaatatac tgaacattat acagatactt
      121 ttataacatt caaggaaatt atgagaactg tttctaacat ataccacaat tgtgtaccag
      181 ataagattaa aaaccgaaga aatactgatc aactgaagca acgcgataca gtgattattg
      241 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
      301 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      361 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      421 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      481 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      541 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      601 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      661 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaatc catgaaaagc
      721 ttgcccttaa gggcattact atatccgttc cgccacgtaa aaacatggat aaatcagaaa
      781 aactagacca cagcttactt ggaaaacaaa gaaaaacagt tgagactgtt ttttcttcct
      841 tagaaaaatt aggttgtcaa aatttcaact cacgttctgt taaagggcta gagagtagat
      901 ttgaaagcat attactggct tacagtgttc tatta
//
LOCUS       DAPBBR010000160          934 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPBBR010000160 DAPBBR010000000
VERSION     DAPBBR010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.172"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            21..>934
                     /locus_tag="RD488_002822"
     CDS             21..>934
                     /locus_tag="RD488_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7658805.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEV"
BASE COUNT          329 a          174 c          177 g          254 t
ORIGIN      
        1 attataagga gtgagtacaa atgacctata cccatcttac accaactgaa ctcgtaatga
       61 tagaagctta tttcaatcaa tcacactctg tttcaaaagt agcccatctg gtacaacgtt
      121 ctcgacaaac catttataat gtctatcgtt ttcttaaatc tggtggaagc gcaataagct
      181 actatgaaca atataagaaa aacaaacgta actgcggaag acgtccgatt gtgttaccag
      241 atgggcaaca agaatacatt caaaaaaagg tggctcaagg gtggactcca gatgtcctta
      301 ttggtcgagc agagtttcct attgcttgtt cggtacgtac actatatcgg atgtttaaag
      361 ataaaacctt tgaccctcac gatttaccaa tgaaagggaa aagaaaacca aacggacata
      421 aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca ggatagaaca actgattata
      481 tacagttcaa tcatgagttt ggtcacctag aaggtgacac cattgtcggt ggaaaacata
      541 aaagtgcggt gatcacgtta gttgagcgat tatctaaagt gatcatcacc ttgaaacccg
      601 ctggtaggca agctatagat attgagaata gactgaatca atggtttcaa tctgtaccga
      661 aacacttgtt taaatccatc acatttgatt gtggaaaaga gttctcgaat tggaaaaaga
      721 ttagtaatac caatgatatt tcgatttatt tcgctgatcc aggaacacct tctcaacgag
      781 gactaaatga acattcgaat ggcttattac gtaaagatgg cttatataaa gctatggatt
      841 ttaataaggt atccgaaacc tttatccaat cggtggcatc aaaacgaaat catattccta
      901 gaaaatcatt acactatcgc acaccattgg aagt
//
LOCUS       DAPBBR010000161          925 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPBBR010000161 DAPBBR010000000
VERSION     DAPBBR010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.173"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..582)
                     /locus_tag="RD488_002823"
     CDS             complement(<1..582)
                     /locus_tag="RD488_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658806.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYK"
     gene            complement(822..>925)
                     /locus_tag="RD488_002824"
     CDS             complement(822..>925)
                     /locus_tag="RD488_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658807.1"
                     /translation="WTCPICHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          286 a          162 c          122 g          355 t
ORIGIN      
        1 tttgtaaaaa tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat
       61 gtcaatattt ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa
      121 ttccctgtaa ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc
      181 acccattcca ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc
      241 agtttgttta tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc
      301 aaaaattttt tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac
      361 tgataattga tactctatat tacatgactt aattagtttt ttagatcccc cctccagata
      421 ggcatatgtt tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc
      481 ataaattaaa aatgactgtc tatttagccc ataatctaat acaacttctt catactcata
      541 tttctttaaa tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt
      601 gttatttatt gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt
      661 agtgaactac tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc
      721 ttgggaagag agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac
      781 caagctatcc ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag
      841 tgtagcctta gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga
      901 gtatgacaaa tagggcaagt ccatt
//
LOCUS       DAPBBR010000162          855 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPBBR010000162 DAPBBR010000000
VERSION     DAPBBR010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.174"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..518)
                     /locus_tag="RD488_002825"
     CDS             complement(<1..518)
                     /locus_tag="RD488_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HDT7658808.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDP"
     gene            complement(529..735)
                     /locus_tag="RD488_002826"
     CDS             complement(529..735)
                     /locus_tag="RD488_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDT7658809.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          233 a          190 c          140 g          292 t
ORIGIN      
        1 ggatctgtat gatcgcccca gatgttttgt gttacccata aatgcgattt gattcccggt
       61 tggttataag gagtgtccaa cgttaatgga ataccatatt tcattgctga atctctagcc
      121 aattcaacgt atgccttgta gtttttctca aacgttgctt tatcatgtgt gtgttgtaac
      181 tcaatctgca caggactgtt ggcattagca tacgaaccag caccgtactg tacataacca
      241 ggttgaccga cttgataaac aattccgccg tctcccacaa tataagcagt ataagcgcta
      301 gtccatgaac gttgcatata ctgcgcttca ttgcgtcctg ttgctgtttc attagccgtt
      361 tcatgcagta aaatatactg attatttgct acttgtgagc taccttcatt tgcgcccaaa
      421 ttaaattcat tgttgatagt ataggcaaat ccgttaattg gcaataaaaa aagagccgtt
      481 aacaggctca tcgcagtaat agtaattttc tttttcatat ctatcctcct atttatctga
      541 tgaaattttc ttatacgttc gatttgatac acctaaaata ctccctagaa atgctccaaa
      601 acctgtaata atcatcaccg ttatatctgt gtaccgccag ttaacacctt ttccgacaag
      661 accgacaaaa gtcgctaaag cggggataac tactatagcg atccatttca aaatatcaaa
      721 ggttctattg ttcatactat ccacctccct tcattggttg ggctactttc tttttcaatc
      781 gcttgttttc ttctatcaat atttctcttt ctgaaagcaa ggcatcaatt tgcccgtcca
      841 gttgttcaat tttat
//
LOCUS       DAPBBR010000163          766 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPBBR010000163 DAPBBR010000000
VERSION     DAPBBR010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.175"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            661..>766
                     /locus_tag="RD488_002827"
     rRNA            661..>766
                     /locus_tag="RD488_002827"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          135 g          192 t
ORIGIN      
        1 gaattcctta ggcagctttt gctgtgtaga aaggaataaa taataacgaa agttcaaaag
       61 ctaatgccga ctattctaga cattaaagaa gacgaaaacg aacgataaag aaagaaaagt
      121 tatgaataat cgtttattga aaaaaacttg aaaaaataca aaaaattcgt tgaccaagct
      181 aaatttagtt ggtatattat tacttgtcca aaagacagaa gaaaatattt attcaaaaac
      241 ataacaaaaa agttattgac atgttactaa cgacatgata agataactga gtcgttaaaa
      301 aagaaccact tgcgaagctt gattctatcg aaaaaaactt caaaaaagtt cttgacaaat
      361 aacaaacgat aagttatgat aaatgagttg ccgaaagatt tcgaaaaacg aaatcgaaaa
      421 aaacttttaa aaaagagttg acaatcgctt gtctctctga tatgatataa aagttgctac
      481 ggcagccaaa aatgaatcgg gaaacactct cgatgaagta gacctttgaa aactgaacaa
      541 agtaagacaa accaaatgtg tagggcgtct tgattcaatt caagacaaca aacattttta
      601 acaagcaagc aatatgctag caaacaaatt gagcttaaca atcgcaagat tgttcgaact
      661 ttttatgaga gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa
      721 gtcgaacgct tctttttcca ccggagcttg ctccaccgga aaaaga
//
LOCUS       DAPBBR010000164          748 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPBBR010000164 DAPBBR010000000
VERSION     DAPBBR010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.176"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            21..>748
                     /locus_tag="RD488_002828"
     CDS             21..>748
                     /locus_tag="RD488_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7658810.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAI"
BASE COUNT          262 a          129 c          140 g          217 t
ORIGIN      
        1 attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa cttgtaataa
       61 tagagtctta tttcaaaatg aatcaatctg ttgctaaaac tgcccattgc ttgaatcgtt
      121 caagacaaac gatccataaa gtatatctgt tcttcaagca aggaaaatca gccttagaat
      181 attatcaaca gtataagaaa aacaaatcaa actgtggtag acgtccgctt gttttacccg
      241 aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc gatgtgattg
      301 ttggtcgtgc agcgtttcct attagttgtt ctgctcgtac catttatcgt atgttcaaaa
      361 aggggctatt tgattcttct gacttaccga tgaaaggcaa gcgtaaaccg aatggacatc
      421 aagaaagacg tggaaaacaa actttccgcc gctctattca tgaacgtgaa aaggattata
      481 gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt ctgaaacata
      541 aaagtgctgt aattacctta gttgaacgat tatcaaaagt tatcatcaca ttgaaaccgt
      601 gtggtagaca agcgattgat attgaaaaaa aattaaatca atggtttgaa tctgtaccga
      661 aaaacctatt caaatccatc acttttgatt gtggaaagga attttcaaat tggaaacaga
      721 tcagtaatgt caatgatatt gccattta
//
LOCUS       DAPBBR010000165          734 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPBBR010000165 DAPBBR010000000
VERSION     DAPBBR010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.177"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            53..>734
                     /locus_tag="RD488_002829"
     CDS             53..>734
                     /locus_tag="RD488_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HDT7658811.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
BASE COUNT          239 a          129 c          153 g          213 t
ORIGIN      
        1 tttatggatg atgtctacag tcttttcttt tataatagat ttatgaaaac gaatgcaagg
       61 agtgatagct atgatgtcta aaaacaatac gaatggtaga aatcaatttg cgatgcttac
      121 gattgatgat ctagttcctc aagatcatct cgttcgaaag attgatgccg cgcttgattt
      181 tgaatttatt tatccaatcg tcgaagccac ttactccgat ttaggtcgcc caagtatcga
      241 tccagtgatt ctgatcaaat tggtgtttat tcagtattta ttcggtatcc gttccatgcg
      301 acaaaccatt aaggaagtcg ataccaatgt cgcttaccgc tggtttttag gctactcctt
      361 cgaggagaaa atcccccatt tctcaacttt tggaaagaat tatgttcgcc gatttagaga
      421 aacgacggtg tttgaggata tttttgccta tattttagaa caagcagtta aagcaggttt
      481 tgtaacagag gataatttgt atctggattc tacccacatc aaagctaacg ccaataaaca
      541 taagtttacg aaagaaatga cccatgatga agcgaaagcc tatcaggatg aattagaaga
      601 tgagatcaat cgtcaacgaa tagaggctgg aaaacgccct tttactttgg acttagaaaa
      661 ggaagtgaag ctgaaagaaa gaaaaataag taaagctgat ccggaaagcg gctactacgt
      721 caaaggcgaa cgag
//
LOCUS       DAPBBR010000166          698 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.178, whole genome shotgun sequence.
ACCESSION   DAPBBR010000166 DAPBBR010000000
VERSION     DAPBBR010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.178"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..688
                     /locus_tag="RD488_002830"
     CDS             <1..688
                     /locus_tag="RD488_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658812.1"
                     /translation="LERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFPNAQLIIDR
                     FHIVQHIGRTFLNHRVKETTVRLKGNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVW
                     RASFKDYLTESEIADRLLAACPNLRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLP
                     ETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRNFYNFKLRIM
                     IRHGKTFLTK"
BASE COUNT          230 a          140 c          130 g          198 t
ORIGIN      
        1 tttagaacgc tatttttctc ggttttcatt agcgactcgt gaagccgttc aattgattgt
       61 tattgatatg tatgcgcctt atgtttcgtt ggtgaaaaag cttttcccga atgctcagtt
      121 gatcatcgat cgtttccaca tcgtccaaca tattggcaga actttcttga atcatcgagt
      181 gaaagaaacc acggtacgac ttaaaggaaa ttcccactct caacgagggt tagggaaaaa
      241 attgaagcgc tattggaaac tcctacaaaa agaagaagca aagttaaact atgaaaaacg
      301 ggtttggcgt gccagtttta aagattattt gactgaaagt gagattgccg atcgactgtt
      361 agctgcttgt cccaacttac gccaaggcta tcagttatac caagacattc tttatgcggt
      421 aaagaaaaga gatcagtcac tatttgagga ttgtttaact agagacatta gcggtctgcc
      481 agaaacctat acaaccactt tacgaacgtt taaaaagttt ctgccacaga tccaaaatgc
      541 gcttcactac agctattcaa acggaccatt ggaatgctta aacaaccaca tcaaagtatt
      601 aaaacgcaat gcgtacggct ttcgcaactt ttacaatttc aaactacgaa ttatgattcg
      661 tcatggcaaa acatttttaa ccaaataaac agaacaga
//
LOCUS       DAPBBR010000167          678 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPBBR010000167 DAPBBR010000000
VERSION     DAPBBR010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.179"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..129
                     /locus_tag="RD488_002831"
     CDS             <1..129
                     /locus_tag="RD488_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7658813.1"
                     /translation="SGITMEKTKKGLLKQWDRKSHELFISILKELEEHENWYAEVE"
     gene            130..678
                     /locus_tag="RD488_002832"
     CDS             130..678
                     /locus_tag="RD488_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658814.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          283 a           95 c          145 g          155 t
ORIGIN      
        1 tcaggtatta cgatggagaa gacaaagaaa ggtctcttaa aacaatggga tcgcaaaagc
       61 cacgaattat ttatcagtat tttgaaagaa ttggaagaac acgagaattg gtatgcggag
      121 gtggagtaat tggctgacat caaaggactt gatatttttg ggaacaacaa aggactcgcc
      181 aaaataaaaa aagaagcaga agcaaagaaa aagcagcaag caattacacc atctgaaaat
      241 aagcaattag aagtgcacca agttcaagaa ataaaaactt cctccaatgt tgaaagacag
      301 agtagaggaa gaacaaaaaa agttggcgca ccaatcagaa agtttgataa ggtttattcc
      361 accaagcatc ctttaaaact gtcgactttg ttaaatgcga cttccagagt tttagtagaa
      421 aagtatgaga ctaatatgac aagagatgaa ttgcttagaa aagctttaga tgagtatatt
      481 aaacagaatc ttacgcaaga agataagcaa gatttgttta atgacgtggt gaaagaacta
      541 gacttgttca gagaaaaata tccaattgtt ccagaattag atgatcgtgg agaaataata
      601 agaactacca gtcagataaa acaagatacc gaagactcac tgcgcaaagg gtggggaatg
      661 aataataaag ttagataa
//
LOCUS       DAPBBR010000168          629 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.180, whole genome shotgun sequence.
ACCESSION   DAPBBR010000168 DAPBBR010000000
VERSION     DAPBBR010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.180"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(42..620)
                     /locus_tag="RD488_002833"
     CDS             complement(42..620)
                     /locus_tag="RD488_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658815.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT          244 a          111 c           81 g          193 t
ORIGIN      
        1 aaatccctca cctaatacta aagcgaggga ttttttgtat attatctgtt tatcaccgtt
       61 attataaagg tacaaatacc aagcacggtt aatccaaatt gcataaattc atttttttgt
      121 acactcatgc ttttcattag ctctttaact gccattagta ctaagatggc gataacaaca
      181 taaagtatat agtacgtccg cattccggaa gcccatactg tgggagaaaa tcccataatt
      241 aaccttgaac aaaatcccat tatcatcaaa ataactaaaa aaatagaagt tttcttattg
      301 tcaaaactta aataaattcc aacaattaaa catagtaata atgccaagac tactaaagta
      361 gctatccaag tacctggata aaaaagtgac agtttcgttc ctaactctgt aaagagatta
      421 ttcaggttac tactactcca aatcattgcc cttttatttc cattgacgta agtaaagctt
      481 tgacccattg tattaccaaa ataaataatc aggtttaaga aaaacggtaa tgcagtcaat
      541 atacgcacat aatagttttg acatttccta tatgttagaa ggaaaattaa gaaaaatagc
      601 aataaaaata agatattcat gtctaaaaa
//
LOCUS       DAPBBR010000169          619 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.181, whole genome shotgun sequence.
ACCESSION   DAPBBR010000169 DAPBBR010000000
VERSION     DAPBBR010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.181"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(26..379)
                     /gene="tnpB"
                     /locus_tag="RD488_002834"
     CDS             complement(26..379)
                     /gene="tnpB"
                     /locus_tag="RD488_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDT7658816.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(369..563)
                     /locus_tag="RD488_002835"
     CDS             complement(369..563)
                     /locus_tag="RD488_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658817.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          179 a          133 c          103 g          204 t
ORIGIN      
        1 acattttttg tgttaacccc ccagcttaaa aaactccttt ttttcctggc aaaatagctc
       61 gaggttgatc gatacttaat ccttctaaca accatcgaac ctgttggttc gttaaggttc
      121 gaacttcgtc tttcgtccga ggccatttta acttgccgtt ttctatccgc ttataacaga
      181 gaagaaaacc atcaccgtcc caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa
      241 ataaaaaaac ggcatcttcg taaagctcga gttgatactc ttgttgaata agactggcaa
      301 gaccatcaat tccttttcgc aaatctgttt ttccgcacac aatataaata tgtttggttt
      361 gaagtaaatc ataaagcatt ggacaacagt tctttcaaaa tagcttgaag aatataattg
      421 ttaataccgt tatagatcaa aacttcagaa ccattctctc ttttgatgcg catcgctaac
      481 ttggcagccg cgggtttacc tttttctggt gcactctttt cgtttcctaa ttggacagga
      541 acaatctcat ttaatttata catagaaaac ctccagactt cttgatagct caagtatatc
      601 ttgaggtgca tttgttagt
//
LOCUS       DAPBBR010000170          593 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.182, whole genome shotgun sequence.
ACCESSION   DAPBBR010000170 DAPBBR010000000
VERSION     DAPBBR010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.182"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..580
                     /locus_tag="RD488_002836"
     CDS             <1..580
                     /locus_tag="RD488_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7658818.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          204 a          105 c          122 g          162 t
ORIGIN      
        1 aggaatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata cagatccttg
       61 cggttatctt tctgaaatgg gtgtaagtaa agaaaaacta gcctatgatt tggctcatgg
      121 ttttacggat gataatccaa ctacttcgga tgataatcca actacttcgg aggataaacc
      181 agtaattgat ccaactcgag caggtgctgc aaattctacg ctgacagatg gaacaaatta
      241 cgcccacgtt gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag ctggatggca
      301 cattgctaat tataaatacg agtatatttt cattatggac tacaatactg gaaaagaact
      361 agctagagta agagctgatg ggatttatag accagacgta aatcaagctt ataatacttt
      421 aggaaatgtt ggctatcatg tatctttcaa tatgcgtgat ttccctaata agaaagtata
      481 cgtcatgatg cgtgcgacaa acgatccaga aggaaatact aagggtggag cacaagattt
      541 tcatgacaag cgttggtatt taaatattcc acaacgataa aaaattcccc cct
//
LOCUS       DAPBBR010000171          593 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.183, whole genome shotgun sequence.
ACCESSION   DAPBBR010000171 DAPBBR010000000
VERSION     DAPBBR010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.183"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>593
                     /locus_tag="RD488_002837"
     CDS             <1..>593
                     /locus_tag="RD488_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HDT7658819.1"
                     /translation="GVSLPEDRLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATK
                     LDDKSDADKYNPEGQKVTTELNKEPDASEAIKNKKDLPKDTMYTWKEKVDVSTAGNKK
                     GTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPTL
                     PEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT"
BASE COUNT          235 a           99 c          133 g          126 t
ORIGIN      
        1 ggcgtaagct tgccagaaga tagacttccg gtgttgaaag caaaagatgg ttacacagat
       61 gcgaaatggc cagaagaagc aacccaacca attacggcag atgatacaga atttgtatca
      121 agtgcgacaa aactggatga taaatctgac gctgacaagt ataatcctga aggtcaaaaa
      181 gtgactacag aattgaataa agaaccagac gcatctgagg caattaaaaa taagaaagat
      241 ttaccaaaag atactatgta tacttggaaa gaaaaagtag atgttagcac agctggaaat
      301 aaaaaaggta ctgttgtagt gacatatcca gatggatcat ctgatgaagt tgaagtggat
      361 gttacagtga cagacaatcg ttctgacgcc gataaatatg aaccaacagt agaaggcgaa
      421 aaagtagaaa ttggaggcac agtagattta acagataatg ttactaactt gccaacatta
      481 ccagaaggaa caacagtaac agatgttact cctggcggta caattgatac caacacacca
      541 ggcaattacg aaggtgtcat tgaagtaacg tatccagacg gtacgaaaga tac
//
LOCUS       DAPBBR010000172          587 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.184, whole genome shotgun sequence.
ACCESSION   DAPBBR010000172 DAPBBR010000000
VERSION     DAPBBR010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.184"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..217)
                     /locus_tag="RD488_002838"
     CDS             complement(<1..217)
                     /locus_tag="RD488_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658820.1"
                     /translation="MEDKKEKLFDLIANAYNSKSYNNVEVKEGFLQDAKKIREDKPYP
                     EIIISVYKHLSKLKAEERMDRLQLTRQK"
     gene            complement(207..410)
                     /locus_tag="RD488_002839"
     CDS             complement(207..410)
                     /locus_tag="RD488_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HDT7658821.1"
                     /translation="MILGIVLLSVSTLGITVDAATYYGNGVYCNTQKCWVDWSRARSE
                     IVDRGVKAYVNGFTKVLGGVGGR"
BASE COUNT          193 a          114 c           53 g          227 t
ORIGIN      
        1 ttttctgtct agttaattgt agcctatcca tgcgttcctc agcttttaat ttagataaat
       61 gtttgtacac tgatataata atttcaggat atggtttatc ctctcgtatt ttcttagcat
      121 cttgaagaaa tccttctttt acttctacat tattatatga ctttgaatta tatgcattcg
      181 caattaagtc aaaaagtttt tcttttttat cttccaccga ctccacctag cacttttgta
      241 aaaccattaa cgtaagcttt tactcctcta tcaacaatct cagagcgagc tctactccaa
      301 tctacccaac atttttgagt attacaataa acaccatttc cataataagt tgcagcatct
      361 actgtaattc ctaaagtaga tacactcaat aaaacaattc ctaaaatcaa aaaatactaa
      421 caaatttttt cttcatataa ttgcctccct tttttataaa acaattatat gtaattttca
      481 gaacattttt gcaaaatttt cataaatagt atctttagtg tcataatcgt caccaatatt
      541 ctgtaagatc aatcaaattt tatctcacta ataataatag tcttaat
//
LOCUS       DAPBBR010000173          557 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.185, whole genome shotgun sequence.
ACCESSION   DAPBBR010000173 DAPBBR010000000
VERSION     DAPBBR010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.185"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..477
                     /locus_tag="RD488_002840"
     CDS             <1..477
                     /locus_tag="RD488_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7658822.1"
                     /translation="VSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGT
                     NYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQA
                     YNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          201 a           95 c          107 g          154 t
ORIGIN      
        1 gtaagtaaag aaaaattagc atatgattta gctcatggat ttaccgatga aaatccaaca
       61 acttctgaaa acaagcctgt cattgatcca acacgagctg gtgcagctaa tcctacactg
      121 acagatggaa cgaattacgc ccacattgat cagtttggag aaatcgaaaa tgcaaatttg
      181 catgtagctg gatggcacat tgctaactat aaatacgagt atatcttcat tatggattac
      241 aatactggga aagaattagc tcgagtaaga gctgatggaa tttatagatc agatgtaaat
      301 caagcttata atacttctgg aaatgttggc tatcatgtat cttttaacat gcgtaacttc
      361 cctaataaga aagtctatgt catgatgcgg gcaacgaatg atccagaggg aaacactaaa
      421 ggcggtgcgc aagatttcca tgacaaacgt tggtatttaa atattcctaa acgataaaaa
      481 tagctcctcg ttgaggagca ttacataact atattgacaa ctataaaaat cattcgataa
      541 aatagtgatg ttatcgc
//
LOCUS       DAPBBR010000174          548 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.186, whole genome shotgun sequence.
ACCESSION   DAPBBR010000174 DAPBBR010000000
VERSION     DAPBBR010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.186"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>548)
                     /locus_tag="RD488_002841"
     CDS             complement(<1..>548)
                     /locus_tag="RD488_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7658823.1"
                     /translation="SLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW
                     ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT
                     IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQE"
BASE COUNT          147 a          119 c           84 g          198 t
ORIGIN      
        1 tcctcttgtt cgagttccaa tgcttctaat gatttaccgg acatatattt ctctaaaagg
       61 tcatcgtttc cctctattac cgtatcccat tgttcagatt cggtaaagtt cgtcacacac
      121 atattaggat acagttctac cttctgtttg attacaattt cggcagaaag tttctcttta
      181 atatcctgat aaaccgttga taaatcaatt ccattttggt caatcttatt gataaaaaag
      241 attgtgggaa tccccatttt cctaagtgca tgaaataata tacgagtttg tgcttgtacg
      301 ccatcttttg cagaaatcag tagaattgcc ccatctaaaa ctgataatga acgatatact
      361 tctgctaaga aatccatatg tcctggcgtg tctatgatgt tcaccttcgt attttcccac
      421 tgaaaagagg ttattcctgt ctgaattgta attcctctct gacgttctaa aagcgtatta
      481 tccgtcctcg ttgtaccttt gtccacgctt cctaattctg taatcgctcc actgttatat
      541 aataagct
//
LOCUS       DAPBBR010000175          542 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.187, whole genome shotgun sequence.
ACCESSION   DAPBBR010000175 DAPBBR010000000
VERSION     DAPBBR010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.187"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(70..156)
                     /locus_tag="RD488_002842"
                     /pseudo
     CDS             complement(70..156)
                     /locus_tag="RD488_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          208 a           87 c           52 g          195 t
ORIGIN      
        1 tgaaatacct ctttgttact cataattata ccataattag tcacgaatgc aaccaataga
       61 aaaaaatact tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt
      121 ttgtgaagca ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct
      181 tctattataa aagaagatat atattatttc ttaattacct actaccttaa accaaaattt
      241 aagtactacc taatttaagt agtacttaaa taatctaaaa aatagttatc ccaattgtta
      301 tgcttttata atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata
      361 tttaggtagt gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca
      421 actaagttat gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta
      481 caagcatgta gttttatctg ttaattatgt actacctaaa taaattagtt tataattaac
      541 aa
//
LOCUS       DAPBBR010000176          517 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.188, whole genome shotgun sequence.
ACCESSION   DAPBBR010000176 DAPBBR010000000
VERSION     DAPBBR010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.188"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
BASE COUNT          169 a           87 c          117 g          144 t
ORIGIN      
        1 tatccataaa actaatataa agcttggtac gattctgttt gtaagacata cgaatagtat
       61 cagaggtagg agccaagctg cctgatatta aattatcgat aaagtagaaa ggttaagcat
      121 tagccgctgc aataactaat gctaggagac agcaacgtgt aaccattacc gcacgtgttt
      181 ctgaatggtg gtagcgaccg atttgaacgg ctagggcgga aatacggtgc aaatgcacgg
      241 tggtttcatg caatgcttac agggcgtatt ttgtaagggt atgtaacgga gataattccg
      301 acggtaatgg atgtgagagg ccaagccgac gctgacggta gggcaaacaa acatagttgc
      361 actctagcga tcgttattta tttttaacgg tcaaactagg gtacaactat gcttaaaaca
      421 cttcgcctca acttctggta gcaaaagtga ttttgaaagt caaaatattt tttatgagtt
      481 atttacaatt ctaaaaaaca agtgtattaa tctacta
//
LOCUS       DAPBBR010000177          510 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.189, whole genome shotgun sequence.
ACCESSION   DAPBBR010000177 DAPBBR010000000
VERSION     DAPBBR010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.189"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..405
                     /locus_tag="RD488_002843"
     CDS             <1..405
                     /locus_tag="RD488_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658824.1"
                     /translation="ARLHEKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHK
                     LAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREW
                     TCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          180 a           79 c          103 g          148 t
ORIGIN      
        1 gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa gttgagtaca
       61 gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa aggtatgttg
      121 cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt tgtgactaaa
      181 ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa atggtttccg
      241 tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct tgaaattcga
      301 gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc tagtatcaat
      361 attctgaccg aaggtctaag actacattct atgggattgg cttagatcca atcatcaaga
      421 accgtaggaa ctacggggat agcttggtaa ataagagaca ccgctgttag taaagaaata
      481 cgctatcaag tatgctctat tcccaagaag
//
LOCUS       DAPBBR010000178          507 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.190, whole genome shotgun sequence.
ACCESSION   DAPBBR010000178 DAPBBR010000000
VERSION     DAPBBR010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.190"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..491)
                     /locus_tag="RD488_002844"
     CDS             complement(<1..491)
                     /locus_tag="RD488_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7658825.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMD"
BASE COUNT          139 a          106 c           95 g          167 t
ORIGIN      
        1 tcatccatac acaacaccgt cggaaggaag ttcatacgtg actggtaatg cttcgttgct
       61 tcacgcaaga tccgtgtcac cgtcccatcc gagacgaagt acttcttagc gattagttta
      121 cgtgattgat tttcgtacag ttccatgaga attgcctgct tcagttcctt tgttagttga
      181 tgatgttcat caactaagtc cgttttcgca gaaaaggtcc ttccacaatc atggcagaga
      241 aaacgggtac gttttaattc taaaatagtt aacttttctt tgactttcaa catctgagtg
      301 cgtgtcgtat aggaaccgtt gcggataata cgaaccgatc gacagtgttc acaataggaa
      361 ggagagtcat ccaattttcc tttaataaac tgcgcttgaa cgcctttata ttctttttca
      421 atcagccatt cttcatcaaa aaataaatgt ttatctgtta atccgagtaa ttttctagta
      481 tgattatcca ttgagagact cctttgg
//
LOCUS       DAPBBR010000179          490 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.191, whole genome shotgun sequence.
ACCESSION   DAPBBR010000179 DAPBBR010000000
VERSION     DAPBBR010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.191"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..415)
                     /locus_tag="RD488_002845"
     CDS             complement(<1..415)
                     /locus_tag="RD488_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658826.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFF"
BASE COUNT          187 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaaacgg ctttccaaat gatgaaatac ctaaatctaa cttattaaga aagttgaaat
       61 ttttatattc aggaaaccat ttattaattt catgtgcagc acgtaatgca ttccctggag
      121 ttgtcaaaga gaaaattaat tctgctaagc ttattattga aaatactgat aacttataat
      181 tatatcgtcc attgacaatc aaatataaac taactatact tgttagaaca aaaaaacagg
      241 cgttgacttg ttcttgatta gttaaaaata tcaataaagg aatacttacc caatatattt
      301 ttctatttat ttcttctcct cttaagagtt gaaaaaacgg ataaaaagtt agtaaactaa
      361 atgctactgg ccactgatag ttcaaggtgg ttgctctcca accggtttcc cccattactg
      421 tcaatggtat taaacagtat atagagcaaa ccaataataa atttttaaca tttattttct
      481 caaaaacata
//
LOCUS       DAPBBR010000180          487 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.192, whole genome shotgun sequence.
ACCESSION   DAPBBR010000180 DAPBBR010000000
VERSION     DAPBBR010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.192"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>487)
                     /locus_tag="RD488_002846"
     CDS             complement(<1..>487)
                     /locus_tag="RD488_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDT7658827.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DAPBBR010000181          486 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.193, whole genome shotgun sequence.
ACCESSION   DAPBBR010000181 DAPBBR010000000
VERSION     DAPBBR010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.193"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
BASE COUNT          166 a           65 c           82 g          173 t
ORIGIN      
        1 ataacgtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc atgtatccaa
       61 aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa aaaatgagat
      121 aaaaagtaaa tggaatcatt taaggtaatc tgaaataaaa aatatacagc cctgtggtac
      181 tttacctaca aggctgtata tattttttac tctcagcgtt tttgactccg tgtctgactc
      241 cgttttattg attttgaatg ttattcaatg accatttaac aggtcaaatt tgatgttttt
      301 gattccgtat gacgccgttt gatatctagt gatatagtga tttgagtcta catcgaataa
      361 gggaataaac caataaaaaa tgatttagaa tattaaaata acaaaaaaga ggactacctg
      421 tattagtcct cttttttgac cagattttga ccagtctatt ttacatccta gtatatttat
      481 atgagc
//
LOCUS       DAPBBR010000182          484 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.194, whole genome shotgun sequence.
ACCESSION   DAPBBR010000182 DAPBBR010000000
VERSION     DAPBBR010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.194"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            43..249
                     /locus_tag="RD488_002847"
     CDS             43..249
                     /locus_tag="RD488_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658828.1"
                     /translation="MVKFPQFKLNPAASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQ
                     ISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          211 a           62 c           50 g          161 t
ORIGIN      
        1 ggtaaaaaaa taaaaaaatg tgacaagtgt tttgaatcag ctgtggtaaa gtttcctcaa
       61 tttaaactaa atccagctgc ctcgatacaa tttcaaggac atgtatttga tgttttagct
      121 aaagataaca taaaaaaata caaaaaaggt aatatattcc atattgatat acaaatatct
      181 tctaatttag aagatataaa aaaagccttt aaaattaaaa caattggcac tgctcctaat
      241 tttaaataac aaaaaaatta ctagataatc taaaaacagg atggcattat gagaacaata
      301 actaaacttc ctatatcaca tattttgtaa ttagtgaaaa gcaaattgac tactatcata
      361 agttaatgac tctcatctta atatttaaaa tatattcata tttttctatt ttatctaaat
      421 gcgattttca tatctaataa tagaaaaata aacaattaac aataaaaaag tcttcattta
      481 ttgt
//
LOCUS       DAPBBR010000183          483 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.195, whole genome shotgun sequence.
ACCESSION   DAPBBR010000183 DAPBBR010000000
VERSION     DAPBBR010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.195"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1..454)
                     /locus_tag="RD488_002848"
                     /pseudo
     CDS             complement(1..454)
                     /locus_tag="RD488_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          112 a           93 c           85 g          193 t
ORIGIN      
        1 cttgagccgt aggcctttcg gctgcggata aattcttcag cgactacttc ttcaagttct
       61 gattcgtctt tctttggttt tgattgataa taataggact gacgtgatag acctaatatt
      121 ctgcacatcg ctgatatagg gtaaagatgc ttattcgcat cgattacttg tctcttcgtc
      181 cgaatatcag cgctgcttgc tttaaaatat cattttccat ttctaattgc tggtttcttt
      241 tacgtagttc taacaattct ttttgttcag gcgtaagatt atctttttct ttgaatgaac
      301 cactcgtttt agattgcttt acccatttgt caaatgctga agccgttagt tcatattctc
      361 gaatgatttc tacacgtggc tttccagcta agtaaagatt gacgatttgt tgcttgaatt
      421 cttgtgaaaa agttcttcgt gttctcttag acataaaaat tcctcctggt atgttttctt
      481 cta
//
LOCUS       DAPBBR010000184          471 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.196, whole genome shotgun sequence.
ACCESSION   DAPBBR010000184 DAPBBR010000000
VERSION     DAPBBR010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.196"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1..471
                     /locus_tag="RD488_002849"
                     /pseudo
     CDS             1..471
                     /locus_tag="RD488_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
BASE COUNT          174 a           96 c           98 g          103 t
ORIGIN      
        1 tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct cattcaaaga
       61 aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga aaaataagca
      121 actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac gaaaagacaa
      181 gtaattgatg ccaacaagca taaatattcc atatcagcga tgtgcaaaat tctaaatatt
      241 tctcgtcaga cctactatta tcaagcgaaa ccgatcgaaa atgagtccga cttagaagag
      301 atcgttcagg aagagtttat tcgaaaccga aaggcttacg gtacccgaaa attgaagaag
      361 tgtttagcaa agcgtgggct tcaactcagt cggcgccgaa tcggtcgaat catgaaacgc
      421 cgcggattga catctaccta tacgatcgct cattttaaag ggcaacgaac a
//
LOCUS       DAPBBR010000185          456 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.197, whole genome shotgun sequence.
ACCESSION   DAPBBR010000185 DAPBBR010000000
VERSION     DAPBBR010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.197"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(116..400)
                     /locus_tag="RD488_002850"
     CDS             complement(116..400)
                     /locus_tag="RD488_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7658829.1"
                     /translation="MNQMKNEKDQPFDPDYLNRCMKTVVKENKEIREITIHGFRHTHC
                     SLLFEAGATLKEVQDRLGHANSDITLKIYTHVTTEAKRETANKLALYLDS"
BASE COUNT          124 a           68 c           74 g          190 t
ORIGIN      
        1 attgtgtttt atgtgtctta cgtttgttta atatgtatgg aaagccttta ataggtgaat
       61 agaaaattta tttttgttga actaaaaaag aagctaattc gtatgaacta gcttcttagc
      121 tatctaaata taaagcaagt ttatttgctg tttctctttt agcttcagtt gtgacgtgag
      181 tataaatctt caaagttata tcactattag catgacctag acggtcttgg acttctttca
      241 atgttgctcc tgcctcgaat aacaatgaac aatgagtgtg tctaaaaccg tggattgtga
      301 tttctcgtat ttctttattt tctttaacaa cagttttcat acaacgattc aaatagtcgg
      361 ggtcaaatgg ttggtctttt tcattcttca tttgattcac ctcttttcct tttttatttt
      421 tacgaggatg attataccat ttttggttat ctaata
//
LOCUS       DAPBBR010000186          453 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.198, whole genome shotgun sequence.
ACCESSION   DAPBBR010000186 DAPBBR010000000
VERSION     DAPBBR010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.198"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            93..422
                     /locus_tag="RD488_002851"
     CDS             93..422
                     /locus_tag="RD488_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7658830.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          174 a           53 c           81 g          145 t
ORIGIN      
        1 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
       61 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
      121 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
      181 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
      241 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
      301 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
      361 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
      421 gaaatcgttc cttcaaaaca tgtcattaag tat
//
LOCUS       DAPBBR010000187          443 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.199, whole genome shotgun sequence.
ACCESSION   DAPBBR010000187 DAPBBR010000000
VERSION     DAPBBR010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.199"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            2..>443
                     /locus_tag="RD488_002852"
     CDS             2..>443
                     /locus_tag="RD488_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HDT7658831.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKE"
BASE COUNT          154 a           70 c           89 g          130 t
ORIGIN      
        1 gatgaatcat tttaaaggaa agcaatttca gcaggatgtg attattgtag ccgtgggcta
       61 ctatcttcgt tataacctta gctatcgtga agttcaagaa atcttatatg atcgtggcat
      121 taacgtttct catacgacga tttatcgttg ggtgcaagaa tatggcaaac tactctatca
      181 aatttggaaa aagaaaaata aaaaatcctt ttattcatgg aaaatggatg aaacgtacat
      241 caaaattaaa ggaaaatggc attatttgta tcgagccatc gatgcagatg gtttaacctt
      301 ggatatttgg ttacgtaaaa aacgggacac acaagcagcc tatgcttttc ttaagcggtt
      361 agtgaagcag tttgatgaac cgaaggttgt agtcacagat aaagccccct ctattacaag
      421 tgcctttaag aaactaaaag aat
//
LOCUS       DAPBBR010000188          415 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.denovo.200, whole genome shotgun sequence.
ACCESSION   DAPBBR010000188 DAPBBR010000000
VERSION     DAPBBR010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.denovo.200"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..339)
                     /locus_tag="RD488_002853"
     CDS             complement(<1..339)
                     /locus_tag="RD488_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7658832.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAPBBR010000189        20862 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.045, whole genome shotgun sequence.
ACCESSION   DAPBBR010000189 DAPBBR010000000
VERSION     DAPBBR010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.045"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            267..1304
                     /locus_tag="RD488_002854"
     CDS             267..1304
                     /locus_tag="RD488_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7658833.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="RD488_002855"
     CDS             complement(1393..1716)
                     /locus_tag="RD488_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7658834.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="RD488_002856"
     CDS             complement(1703..2410)
                     /locus_tag="RD488_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7658835.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="RD488_002857"
     CDS             2496..2837
                     /locus_tag="RD488_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HDT7658836.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="RD488_002858"
     CDS             complement(3008..3856)
                     /locus_tag="RD488_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658837.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="RD488_002859"
     CDS             4454..5317
                     /locus_tag="RD488_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7658838.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="RD488_002860"
     CDS             5417..5899
                     /locus_tag="RD488_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7658839.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="RD488_002861"
     CDS             complement(6162..6629)
                     /locus_tag="RD488_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDT7658840.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="RD488_002862"
     CDS             6752..7603
                     /locus_tag="RD488_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7658841.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="RD488_002863"
     CDS             complement(7854..9812)
                     /locus_tag="RD488_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7658842.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="RD488_002864"
     CDS             complement(9809..10681)
                     /locus_tag="RD488_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7658843.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="RD488_002865"
     CDS             complement(11023..11895)
                     /locus_tag="RD488_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7658844.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="RD488_002866"
     CDS             12023..12592
                     /locus_tag="RD488_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7658845.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="RD488_002867"
     CDS             12659..13396
                     /locus_tag="RD488_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7658846.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="RD488_002868"
     CDS             13627..14895
                     /locus_tag="RD488_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7658847.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="RD488_002869"
     CDS             15382..15846
                     /locus_tag="RD488_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7658848.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="RD488_002870"
     CDS             15830..16459
                     /locus_tag="RD488_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7658849.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="RD488_002871"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="RD488_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7658850.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="RD488_002872"
     CDS             18338..18784
                     /locus_tag="RD488_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7658851.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="RD488_002873"
     CDS             complement(18983..19498)
                     /locus_tag="RD488_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7658852.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="RD488_002874"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="RD488_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6632 a         3702 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctaagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAPBBR010000190        20762 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.046, whole genome shotgun sequence.
ACCESSION   DAPBBR010000190 DAPBBR010000000
VERSION     DAPBBR010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.046"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..212
                     /locus_tag="RD488_002875"
     CDS             <1..212
                     /locus_tag="RD488_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7658853.1"
                     /translation="ELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSST
                     HRGPSELCGNVFKIEYTKKRQRLAY"
     gene            447..683
                     /locus_tag="RD488_002876"
     CDS             447..683
                     /locus_tag="RD488_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658854.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            690..2642
                     /locus_tag="RD488_002877"
     CDS             690..2642
                     /locus_tag="RD488_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HDT7658855.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="RD488_002878"
     CDS             complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="RD488_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HDT7658856.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3573..4613
                     /locus_tag="RD488_002879"
     CDS             3573..4613
                     /locus_tag="RD488_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7658857.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4711..4899
                     /locus_tag="RD488_002880"
     CDS             4711..4899
                     /locus_tag="RD488_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDT7658858.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4957..5310)
                     /locus_tag="RD488_002881"
     CDS             complement(4957..5310)
                     /locus_tag="RD488_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7658859.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5841..6263
                     /locus_tag="RD488_002882"
     CDS             5841..6263
                     /locus_tag="RD488_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7658860.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6260..6490
                     /locus_tag="RD488_002883"
     CDS             6260..6490
                     /locus_tag="RD488_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7658861.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6988..7188
                     /locus_tag="RD488_002884"
     CDS             6988..7188
                     /locus_tag="RD488_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7658862.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7215..8408
                     /locus_tag="RD488_002885"
     CDS             7215..8408
                     /locus_tag="RD488_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7658863.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="RD488_002886"
     CDS             complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="RD488_002886"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7658864.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10100..11023)
                     /locus_tag="RD488_002887"
     CDS             complement(10100..11023)
                     /locus_tag="RD488_002887"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDT7658865.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11219..11824
                     /locus_tag="RD488_002888"
     CDS             11219..11824
                     /locus_tag="RD488_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7658866.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12132..13148
                     /locus_tag="RD488_002889"
     CDS             12132..13148
                     /locus_tag="RD488_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7658867.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13289..14590
                     /locus_tag="RD488_002890"
     CDS             13289..14590
                     /locus_tag="RD488_002890"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDT7658868.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14636..15298
                     /gene="deoC"
                     /locus_tag="RD488_002891"
     CDS             14636..15298
                     /gene="deoC"
                     /locus_tag="RD488_002891"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDT7658869.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKERALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15319..15717
                     /locus_tag="RD488_002892"
     CDS             15319..15717
                     /locus_tag="RD488_002892"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDT7658870.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15783..16865
                     /locus_tag="RD488_002893"
     CDS             15783..16865
                     /locus_tag="RD488_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7658871.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17077..18639
                     /locus_tag="RD488_002894"
     CDS             17077..18639
                     /locus_tag="RD488_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7658872.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18632..19765
                     /locus_tag="RD488_002895"
     CDS             18632..19765
                     /locus_tag="RD488_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658873.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19765..20721
                     /locus_tag="RD488_002896"
     CDS             19765..20721
                     /locus_tag="RD488_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7658874.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
BASE COUNT         6767 a         3681 c         4264 g         6050 t
ORIGIN      
        1 tggaactcga acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc
       61 atggaagtgc aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat
      121 tttattcatc aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat
      181 atacaaaaaa aagacaacgt cttgcatatt aagtagttca gttttggagt acaaaaagtg
      241 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
      301 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
      361 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
      421 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
      481 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
      541 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
      601 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
      661 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
      721 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
      781 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
      841 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
      901 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
      961 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     1021 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     1081 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     1141 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     1201 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     1261 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     1321 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     1381 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     1441 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     1501 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     1561 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     1621 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     1681 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     1741 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     1801 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     1861 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     1921 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     1981 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     2041 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     2101 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     2161 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     2221 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     2281 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     2341 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     2401 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     2461 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     2521 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     2581 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     2641 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     2701 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     2761 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     2821 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     2881 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     2941 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     3001 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     3061 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     3121 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     3181 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     3241 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     3301 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     3361 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     3421 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     3481 acttacttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
     3541 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
     3601 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     3661 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     3721 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     3781 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     3841 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     3901 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     3961 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     4021 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     4081 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     4141 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     4201 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     4261 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     4321 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     4381 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     4441 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     4501 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     4561 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     4621 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattctt taatatagat
     4681 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
     4741 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
     4801 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
     4861 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
     4921 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
     4981 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
     5041 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
     5101 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
     5161 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
     5221 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
     5281 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
     5341 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
     5401 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
     5461 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
     5521 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
     5581 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
     5641 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     5701 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     5761 cgttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     5821 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     5881 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     5941 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     6001 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     6061 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     6121 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     6181 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     6241 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     6301 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     6361 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     6421 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     6481 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     6541 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     6601 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     6661 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     6721 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     6781 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     6841 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     6901 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     6961 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     7021 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     7081 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     7141 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     7201 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     7261 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     7321 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     7381 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     7441 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     7501 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     7561 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     7621 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     7681 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     7741 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     7801 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     7861 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     7921 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     7981 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     8041 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     8101 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     8161 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     8221 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     8281 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     8341 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     8401 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     8461 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     8521 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     8581 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     8641 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     8701 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     8761 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     8821 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     8881 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     8941 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     9001 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     9061 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     9121 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     9181 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     9241 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     9301 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     9361 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     9421 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     9481 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     9541 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     9601 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     9661 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     9721 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     9781 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     9841 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     9901 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     9961 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
    10021 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
    10081 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
    10141 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
    10201 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
    10261 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
    10321 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
    10381 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
    10441 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
    10501 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
    10561 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
    10621 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
    10681 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
    10741 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
    10801 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
    10861 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
    10921 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
    10981 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
    11041 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
    11101 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
    11161 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
    11221 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
    11281 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
    11341 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
    11401 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
    11461 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
    11521 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
    11581 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
    11641 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
    11701 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
    11761 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
    11821 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
    11881 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
    11941 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
    12001 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
    12061 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
    12121 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
    12181 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
    12241 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
    12301 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
    12361 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
    12421 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
    12481 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
    12541 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
    12601 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
    12661 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
    12721 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
    12781 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
    12841 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    12901 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    12961 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    13021 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    13081 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    13141 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    13201 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    13261 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    13321 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    13381 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    13441 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    13501 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    13561 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    13621 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    13681 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    13741 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    13801 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    13861 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    13921 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    13981 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    14041 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    14101 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    14161 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    14221 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    14281 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    14341 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    14401 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    14461 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    14521 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    14581 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    14641 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    14701 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    14761 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    14821 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    14881 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    14941 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagagc gtgcgcttgt
    15001 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    15061 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    15121 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    15181 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    15241 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    15301 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    15361 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    15421 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    15481 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    15541 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    15601 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    15661 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    15721 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    15781 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    15841 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    15901 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    15961 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    16021 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    16081 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    16141 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    16201 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    16261 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    16321 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    16381 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    16441 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    16501 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    16561 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    16621 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    16681 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    16741 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    16801 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    16861 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    16921 aacaagaatt gttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    16981 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    17041 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    17101 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    17161 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    17221 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    17281 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    17341 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    17401 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    17461 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    17521 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    17581 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    17641 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    17701 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    17761 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    17821 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    17881 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    17941 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    18001 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    18061 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    18121 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    18181 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    18241 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    18301 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    18361 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    18421 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    18481 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    18541 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    18601 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    18661 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    18721 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    18781 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    18841 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    18901 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    18961 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    19021 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    19081 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    19141 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    19201 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    19261 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    19321 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    19381 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    19441 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    19501 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    19561 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    19621 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    19681 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    19741 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    19801 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    19861 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    19921 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    19981 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    20041 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    20101 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    20161 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    20221 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    20281 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    20341 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    20401 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    20461 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    20521 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    20581 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    20641 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    20701 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    20761 tt
//
LOCUS       DAPBBR010000191        17274 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.051, whole genome shotgun sequence.
ACCESSION   DAPBBR010000191 DAPBBR010000000
VERSION     DAPBBR010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.051"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(134..577)
                     /locus_tag="RD488_002897"
     CDS             complement(134..577)
                     /locus_tag="RD488_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7658875.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="RD488_002898"
     CDS             complement(795..2135)
                     /locus_tag="RD488_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7658876.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="RD488_002899"
     CDS             2404..3300
                     /locus_tag="RD488_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7658877.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLAYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPIPSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="RD488_002900"
     CDS             complement(3450..4391)
                     /locus_tag="RD488_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7658878.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFRSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKTAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4516..5637
                     /locus_tag="RD488_002901"
     CDS             4516..5637
                     /locus_tag="RD488_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7658879.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPHGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5895..7397
                     /gene="eat(A)"
                     /locus_tag="RD488_002902"
     CDS             5895..7397
                     /gene="eat(A)"
                     /locus_tag="RD488_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7658880.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKSQPKHLSISYVRQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7425..7991
                     /locus_tag="RD488_002903"
     CDS             7425..7991
                     /locus_tag="RD488_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7658881.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8202..9263
                     /locus_tag="RD488_002904"
     CDS             8202..9263
                     /locus_tag="RD488_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7658882.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9266..10162
                     /gene="murQ"
                     /locus_tag="RD488_002905"
     CDS             9266..10162
                     /gene="murQ"
                     /locus_tag="RD488_002905"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7658883.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10176..12158
                     /locus_tag="RD488_002906"
     CDS             10176..12158
                     /locus_tag="RD488_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7658884.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSAATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12223..12669)
                     /gene="nrdI"
                     /locus_tag="RD488_002907"
     CDS             complement(12223..12669)
                     /gene="nrdI"
                     /locus_tag="RD488_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDT7658885.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12880..14304
                     /locus_tag="RD488_002908"
     CDS             12880..14304
                     /locus_tag="RD488_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7658886.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14485..15258)
                     /locus_tag="RD488_002909"
     CDS             complement(14485..15258)
                     /locus_tag="RD488_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7658887.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15255..16160)
                     /locus_tag="RD488_002910"
     CDS             complement(15255..16160)
                     /locus_tag="RD488_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7658888.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16314..16634)
                     /locus_tag="RD488_002911"
     CDS             complement(16314..16634)
                     /locus_tag="RD488_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HDT7658889.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17108..>17274
                     /locus_tag="RD488_002912"
     CDS             17108..>17274
                     /locus_tag="RD488_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 family protein"
                     /protein_id="HDT7658890.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVN"
BASE COUNT         5573 a         3129 c         3539 g         5033 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggtgttccag
       61 aagtagcttc ttcttatttc ttgaagctga tcacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg gatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgt caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gttccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaataacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat ggctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgattagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccgccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa gcgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttaat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat ggatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttgcttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ctatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc ttttaagcca
     3181 atcccatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaataaataa
     3301 aaaacctaca ttttgaagag attatgtacc gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttc attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc taatatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gttttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cattatggct atagatcgga tttaattttg cttcttgaaa gacttccaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacgaaa catatcatct
     4141 aattgattcg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtgt gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc tccagctatt
     4381 gcgattttca tgttttttct ctcctttatc aatgagttcc cttttagtat atagaaaaat
     4441 ggaagaaaat agcattgttt tgtttgaaaa aaatgaaaaa aagtgtctta cttaagaaga
     4501 aagtgaggga tacagatgga tattttggcg gcaattgatt catttaaagg aagtgcttct
     4561 tcatttgaac taaatcaggc agttctaaat ggctgggaag atcgtaaagg aagaaaaatc
     4621 aatgtgccga ttgcagatgg cggagaaaat actgcagaag caatctatta cgcgctcggg
     4681 ggaacatggc gcaccattga tgggatggat cttttattcc gtcagcgaaa aatcagctat
     4741 ttattgacaa cttggcaagg aaaaaatacc gcagtcatcg aatctgcaca agcattgggg
     4801 ttagatctac ttgataaacc aacggatcaa actatccgac ttgcttccag ttatgcctta
     4861 ggagaactta tcaaagatgc actgcttcaa gaagtagaac aaattattgt cactttagga
     4921 ggaagcgggt gtagcgatgg tggtctagga ttactccaat ccttgggtgc ttctttagaa
     4981 gggtacacag aaggaaatcc tttattatct actaaaaaac ttcattttga tcgaagaaac
     5041 gttcttgttt ctaaagtaaa attgattatc gctgcagatg ttaccaatcc atatacaggt
     5101 caacaaggag ctgcttggca atttggaaga caaaaaggag gaatagatac gacgctagct
     5161 ttcttagata aacaagcagg aaagattgct cagcaaataa aagatttctg ggaggtggat
     5221 ttagatgata ttccaggaag tggagcagca ggcggtattg gtggagccct ttttttgttg
     5281 ggagcgaaga tggtttctgg tttcgattta gtcagccaaa tcactggatt ggaaaaaaag
     5341 atcgaacaag cagatgtcat cattacagga gaagggcgga tcgatcagca aacgatccac
     5401 ggaaaagttc cacacggtgt agcagtgctt gcaaaaaaat atcgaaaacc aataatcgct
     5461 atttgcggaa gtagagacca agagctagaa ggactctctg attttctccc aattgtctta
     5521 agtattcatt tgggtccaat aggtttagaa gaagcaatgg aacacaggca aacattagaa
     5581 aaaacaaaaa tcttaggaca gacacttagc agatttttca ccatcctccc gaagtagttg
     5641 acaaaatcat tttctttatg ctatcgtaat ttcaaatata ggacaaagtg agggatccgt
     5701 gcattgaaaa attaagtcga ttgatgaaag ctgcattcag actgtacctt gtggagacaa
     5761 ggaagcagtg tgcagatttt cgggattggc ttggtttttt cgatgtatgg gtctttttgt
     5821 gtgtatccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg tcttttttta
     5881 cgaggtgatg gaaaatgtct aaaatcgaaa taaaaaatct gacattcggc tacgacagcc
     5941 aaggcacatt attatttgaa caagcaaatc taaattttga cacacaatgg aaactaggac
     6001 ttatcggacg aaacggtcga ggaaagacaa ctttactgaa tattctacaa aacaaactac
     6061 cttatcaagg gcaagtaatc catcagcaag aatttgccta tttcccgcaa cagacaaaag
     6121 ataaagaacg tttaacctat tacgtgttaa atgatattac ggattttgag atatgggaaa
     6181 tcgaaagaga gctccaattg atgcaaacag atcctgaaat cttatggaga gaattcagca
     6241 cactatcggg gggagagaag acaaaagtcc tactggcact tttatttgtg gatgacactc
     6301 atttcccgtt aatcgatgaa ccaacgaatc atttggatat ctctggtaga aaacaagtag
     6361 cggcttattt gaaaaagaaa aaacaaggct tcatcgtggt cagccatgac cggggattta
     6421 tcgatgaagt agtggaccat gttttagcaa tcgaaaaaag tcaactggaa ctttatcaag
     6481 ggaatttctc tatctatgaa gaacagaaaa aacttcgtga tgaatttgaa atggctcaaa
     6541 atgaaaaatt gaaaaaagaa gtcagtaggc taaagaaaac agcagctgaa aaagccgaat
     6601 ggtctcgttc ccgagaagga gataaaacaa agaaacaagt cggattcatc gatactgaat
     6661 ctagacgagt gaataaagga gcagtgggtg ctgatgctgc acggacgatg aaacgatcca
     6721 aagcaatcgt gaatcggatg gagacccaga tcagcgagaa agaaaaacta ttaaaagata
     6781 tcgaatatat cgattctttg acgatgaata gccaagcgtc tcaccataag cgacttttaa
     6841 gcgtagaaga tcttcaatta gggtatgaaa atctgttatt cgagccaatt cattttacaa
     6901 tcgagcctca tcagcgggtg gcgatttcag gtcctaacgg tgcaggaaag tcatccatta
     6961 tccattatct tctgggggca ttcaacggca aggttatagg agaaaaatcc cagccaaaac
     7021 atctgagcat tagttatgta cgccaaaatt atgaagacaa tcgaggaacg ttggcggaat
     7081 ttgcagagaa aaaccaagta gactaccaag catttttgaa caacctccga aagcttggga
     7141 tggaaagaga tgtttttcat aacaagatcg agcagatgag tatgggccaa cggaaaaaag
     7201 tggaattggc taaatcttta tcacagccag ctgaactata tacatgggat gaaccattga
     7261 attatttgga tgtcttcaat caagaacaat tagaacaact gatcttgaac gtgaaacctg
     7321 ccatgttact agtggaacat gatcaaacct tcctggataa agtatctact gagattattt
     7381 ctcttgagag aatctaaccc ttgtaatctc aagaacaaca aggtatggtt aaggggaact
     7441 ttgccaacga aggagagaat cacatgcttt atgtaacgag acacggagaa acaacttgga
     7501 acgcacaagg attagtttgc ggacgggcag atgtgccgct gactgaaaaa ggacagatgc
     7561 aggcacagaa actagcagaa aaggtagtag atttgcctgt tccaatcacg aaaatcatcc
     7621 attcccctct tcaacgagca agagatacag cacaagcagt tgctgatcgt ctcagcttgc
     7681 cgctgaccgt tgatgaacga ttggtagaaa tggattttgg ggattatgat ggactgccaa
     7741 gcaaagatga gaactttcaa aaagcacgtt tagcgttcgc tgtacgattc ccaaatgggg
     7801 agtcagtctt agatgtgtat gcacggatcg ttcctttatt gaaagaatgc atcgaagacg
     7861 aagaaaatgt ctatctgtta gtttgccata atgccttgat aagagtgatc aatgcttatt
     7921 ttcatccgat gcctaatgag gggttcttta cattcatggt agataataca gaattggttt
     7981 cttatgagta attatgtttt tgtgttattt aaataaaata tttcaaggca ctgcttttgc
     8041 ttagcagtgc cttttttagg ttatgacaat tcttttgata atataaactc aacctttaga
     8101 aatgaaattt aattatttta ataaaagtat tgaaattttg tttctttaga tatatactct
     8161 agtcatagaa atgaagacgg atacagaaaa agagggataa tatgtttggc ttttcaatat
     8221 ttatgaacga ttctttgtca gaagagaaga aacagtatat ccgccaaatg gcatccaatg
     8281 gctttgtcgg tattttcact tccatgcata taccagaaga tgatgtttcg gcatatcaaa
     8341 agcgattgat cgaactagga agcgaagcga aaaagaataa actagaattg atggtcgata
     8401 tttcaggaga ggcattggaa cgagcgggtt tttcattaga agatctaacg cctttgaaag
     8461 caattggtgt aacaggttta agaatggatt atcatatttc caatcagcag attgccgact
     8521 ggtcacatca attgaaaatc agtttgaatg ctagcacgat cacgcctaaa gatatcgatg
     8581 aattgaaaga agcagaagct gatttctcac agattgaagc ttggcataat tattatccac
     8641 gtcccgaaac agggctggac aaagaatggt atcagaaaaa aaatcaatgg ctcaaaattc
     8701 aaggtctcct tgtccaaggt tttgtaccag gagatacaga gttgagaggc ccactatatc
     8761 aaggattgcc aactttggaa gaacatcgag ggatccatcc tcttgcaggc gctctagatc
     8821 tattagcaag taacacggat attgtttaca tcggagatgc aggtctgtca gaaaacgttc
     8881 aggagcaatt tgcttctttc caaaaagaac agacagtctt gctccatacg gaacctgtag
     8941 atgaagaatt ttacgaatat atattaggga agcatacgaa tcggcaagac gatgcaagag
     9001 atgtcatacg aagcgcagat gcacgttttc gagagattcc gcctatccca gcaagaaata
     9061 cagctacgcg tatgaaaggg tctattactt tagataacga aaagtatttg cgctatatgg
     9121 gtgagatcca attaaccaaa tatgatttgc cagcggatga aaaagtgaat gtagtagcta
     9181 aagttatcaa agaagagcta ccattgatca accaaatcaa agctggtatg aactatcaat
     9241 ttataagaaa agaaggaaga taaaaatgag caaaatcaat ttagagaacc taacaacgga
     9301 acgcagaaac caagaaactt ttggattaga tgagatgagt atttctcaag ccgttcaact
     9361 aatgaacaaa gaagatcaga aagtggccgc tgcggttgaa aaagaactga caagtatcga
     9421 accagtgatt gctaacacga ttgagtcctt taaaaaaggt ggacgtctga tttatatggg
     9481 agccggaaca agtggaagac taggtgtgtt agatgctgct gaatgcgtac cgacattcgg
     9541 tgtagaaccg gaaatggtca taggtctaat tgctggtgga gaagaagcaa tgactgtagc
     9601 tgtcgaaggg gccgaagatt cttatgagct agggcaagaa gatctaatca agctgaattt
     9661 gacaaaaaat gatatagtta ttggtatcgc agctagcggt cgtacaccat atgtgatcgg
     9721 tggattagat tacgcaaaat cgatcggtgc tgtcacagga acgatttctt gcaataaaca
     9781 agccgaaatc agtaaacacg cggatttccc aatcgaagtc gatgcaggtc cagaattttt
     9841 gacaggctct actcgattga agtcaggaac agcacaaaaa cttatcttga atatgatttc
     9901 tactatcagt atgattggta taggtaaagt attcaataac ttgatggtcg atgtcaaacc
     9961 aacaaatgaa aaactaatcg aacgctcaaa acgaatcatc atgcaagcga cagaagctga
    10021 ttacgaaaca gctgaaaagt actttgaaga agcagatcaa aatgttaagc tggctatcgt
    10081 catgattttg acaaatagtg ataaagagga agctcaagca aaattagctg aagcaaacgg
    10141 atttgtaaaa gggaccttat gagggggaaa agaccatggc aaaaaacgaa ctgactttgg
    10201 aagaactggc aaaacaaatt tataaagggg caggcggcat gggcaatgta gaaagcattg
    10261 tccactgcat gactcgtgtg cgtatgaaga tcatcaatga tgatcttgta aatgtctctg
    10321 aattaaaagc gattccagga gtgcttggtg tagtagaaga tgaacagctt caagtcatca
    10381 tcggacctgg gaaagtgaac aaagtagcac agcaaatggt tgatttggca ggcgtgaaat
    10441 taggagaaaa actttcttct gtaagtgcag ctacagcaaa ttcatcagca tctggaaaag
    10501 accgtgtaaa cgaacgggca caagaaatga aagcggcaca aaaatcgaaa caaaaaccat
    10561 ctaaaatcaa atcggtatta aaagacattt ctaatatctt tgtgccaatg attcctgcat
    10621 ttgtcggtac tgggatcgtg gcagggattg ccgcagtttt agcaaactta gtcacagccg
    10681 gaacacttga tgcagcaaca tggcaacaat atatcgatgt gatgaacatc ttgaaaaacg
    10741 ggatgtttag ctacctagtt atctatacag gtatcaatgc tgcacaagtt tttggtgcaa
    10801 caccaactct tggtggagtt atcggggccg ttgtgatgct gacagggatg aatccggaag
    10861 caccactgaa aaacttattt actggtgaag ctcttgcagc tggacaaggt gggatcctag
    10921 gtgtcatctt cgctgtttgg ctattgtcaa tcgttgagaa aaaactgcat aaagtagtac
    10981 ctgatgcggt agatatcatc gttacaccaa ctctttcatt gattgccatc ggtctgattg
    11041 aaattttctt catcatgcct ttagcaggtt tcatttctga tggcatggtc ggtgggatca
    11101 actgggtact tggcgttggt ggagcatttg ccggcttcgt tctaggcaca ttattcttgc
    11161 cgatggttat gttcggactg catcaaattt tgactccaat ccatgtgcaa atgattgatg
    11221 aaactggtcg tacgctattg cttccaattc ttgcgatggc tggtgcagga caagtgggtg
    11281 cagcattggc attatggatt cgctgcaaaa aagataaaga attaacagaa atgatcaaag
    11341 gagctttacc agtcgggatc ctaggaatcg gcgaaccatt gatttacgga gtaacattac
    11401 ctctaggacg cccatttatt actgcttgta tcggtggagg tatcggcggg gcagtgatcg
    11461 gaatgatcgg aaatgtcggg gctatcgcta ttggaccttc aggagccgct ttgatcccat
    11521 tgatctctga cggtaaatgg ttaggctaca tccttggatt attggcagct tatgctggtg
    11581 gcttcgttgc tacattcttc ttcggtattc ctaaagaccg tttagaaaaa gaagaattag
    11641 cgactgaaac agccacagta aatgaagtgc ctgaaaaagt agtacctcaa acttcagctg
    11701 aaagtgtgac tatcctctca tcagttgctg acggaacagt tgtttcttta gataaagcaa
    11761 gtgatccagt ttttgcacaa aagatgatgg gtgaaggcta ctttgtagaa ccagaaaacg
    11821 gacatatcta ttctccagtt actggggtag tcagctctgt cttcccaacg aaacacgcta
    11881 ttgggatcac aacgccaaat ggtttagaaa tcttgcttca tatgggaatc aacacagttg
    11941 acttaggcgg tacgccattt gatgtgaaag taacagaagg gcagcaagtg acacctgata
    12001 cgcttgtagc agaagctgac ttagaagcga tcaaagcagc aggcaaagaa acatccatga
    12061 tcgtcttggt aaccaatatg gatcgtgtaa aaaactttgt cttggaaaaa acaggtaaag
    12121 caaaagcaaa agcacctgtg atggatgtca aagcttaata tgatagaaac aatagaaacg
    12181 aaagaagaaa ctgaaatcta tttttcagct tcttcttttt tattatttat tgttttctgc
    12241 taaaatctga taaattcgtg tcacatcaga tggtgttccc cgtaattcat aatctgccaa
    12301 gaaaggaaag ccaaatgttt gtgcatattg tttggctgtt agacaatact gattattgaa
    12361 gtttttattt ccgctaccga ctacaccaag acaaagttta tgattgtctt catgttccag
    12421 atattcacgc atcgtttcgg tcaagatttc tgtatcaccg ttatctaaac catttccgcc
    12481 gtctaaataa gtaggaacga aagtaaaaaa tggttctgtt tctttcgtaa aatcactatt
    12541 ttcatggatt tcttttaaag taacttcagg attgacagga tcttctgcat gcattttttc
    12601 agcatattct gctagatgtt tggcaaaggc acgcgtattt cctgaaatcg atatatataa
    12661 aatgttcatg gatcatcctc caattctttc cttttagtat agcatctttt ttaagttttt
    12721 tggtggtgta atttggaaag ggactaggcg ctttgcttgt ataatgagaa aaaagccggt
    12781 agaattatat ttctattaaa gtttttatta attaagtaaa aataaaaaag gtttgttata
    12841 ctttttgata aaagcggttt tattttggag gatgcttaca tggatacaga gcaacagaaa
    12901 aaaggaattg gtttaattcc acttgctgcc ttagtaattg gttcagcgat tggaggtggc
    12961 gtatttggta ttatgacgga catctccgga tcggctggcg gcccagctat tttcagttgg
    13021 gtactcgtag gaacagcaat gttgatgctc tccttgtcga tcaataatat caataaaaaa
    13081 cgtccagatt taaaaggcgg gatctttagt tacgcagaag aaggttttgg ccgtttcgct
    13141 ggttttatca gcggttgggg ttactggctc acatgctggt taggcaacgt agcttttgca
    13201 acattgttga tgagcgcatt aggatatttc ttcccagtat ttgaaggtgg gcaaaatctg
    13261 gcatcgatcg tgatgagtac agtcttttta tggggatatg catggctagt gaatcgggga
    13321 gtcgaaaatg ctagtttcgt caatgctatc gtcacattct gtaaattagt gccattattt
    13381 ttatttattg tagtagctat cagcacgttt tcgatccaac aattcattga taacttttct
    13441 agcgacatta tattgaatgc gaatggacag ccgatcccgt tttccagtca agtattgagt
    13501 tgcatcatgg tgatgctttg ggtatttgtt ggtattgaag gagcctctgt cgtaggttca
    13561 cgagcaaaaa aacaatcaga tgttgggaaa gcaacgattc tagggatatt cggcttgatt
    13621 attatttacg tcttggtttc catgcttcca tatgggacaa tgacgatgaa tcagctgcaa
    13681 acgatcaagg cgcagcctgc tatgggctat gtgtttgaaa tgatggttgg taaatgggga
    13741 gcagtcgtga tcaacggcgg tttgatcatt tctttagttg gtgtttggct ctcatggacg
    13801 atcttaccga ttgaaacaat gggaaacatg gctgaagacg gacttttgcc taaagcatgg
    13861 ggaaaactca acaaaaatgg ggcaccaact tatgctatcg tattgacgac gttatgtacg
    13921 aatgtctttt tactttcatt attattcact gacagtgctt ataactttgc ttacacactt
    13981 ggtacagcag ctattttctt cacgtggctt ttcttaggat tgtaccaaat gaaactttct
    14041 tatcagcgga aagaatgggt ccaattttta gtagggcttt tagcaagtgc ctttcaagta
    14101 tgggctatgc tagtcgtagc ctttaatgaa gtaatgcttg ttcttgttct tttcttgcca
    14161 ggcatttatt tttacctcaa agcacgtaag gagcaaaacg agcctgtaca acatatccac
    14221 ttagataaga ttttacttat aggtgtgacg atggtcggag tgattgcaat ggttttattt
    14281 gccactggga tgcttcacgt atagaagtat aaaagaagta taaagagagg ttgtgagcct
    14341 gtcgtttatt caaaaacata ctaggaaagg agctgtgaca caaatgttgt cacagctcct
    14401 ttttcagaat aaacggtgtt taagagacag ccaatcggca ataaggctga acgtctcttt
    14461 cacagcctct tttttgatga gtcatcatac attttttcgc ttaaatacga gatatcctaa
    14521 tgctaagaac aaaacgatgt aagctaaatt accgaatagc atttgattag tagaaagatg
    14581 agtcaattgc ttcatgatct cttcgtttcc aatttggttt tgcagattca acatactgat
    14641 cggattccat ttgatccact cccatttttg gatgagtgca ataaggatac cagatatgat
    14701 tgacgaagca aaataaaaga cgattcctgc tgagatggat gcaccggaac tattgataaa
    14761 gcaagcaatc atcaacacta aacttaaaat cagccataaa ccgatataac tacccaaagt
    14821 ataagtgaac aagctttgga tcagtgtttg accagtagaa accttctccg tgaaggaaat
    14881 cgaagggaaa agaatcagtt tcatcaacac agtgacaata atagctaaaa ggtataaata
    14941 aacagaataa ataactaatg tgatccattt gcttactaat atttctcctc gagaatactt
    15001 tcgataaagg agatttttca atgtaccata ttgtgcttcc atcgaaatga tcgtgcttgc
    15061 agctgcaatc atgataaaga caatccaaga tgtggcacta aaaagctgag cagtcatttc
    15121 aactggatca atgatcgtcg tgtatttttt ggctagaagt gctgttccta tgagcaaaac
    15181 aactaataga acagataaaa cagcagttga ctttttcttg atcaatttaa ataattcttg
    15241 ttttacaagc aatgtcattt ttcttcttcc ccctttactg aatccagaat ttccaataga
    15301 gaagattcca aatcattcgt cagatgctgg acgtctgtca catggatatt ttgtgcagac
    15361 aatagctgga tcacggttcc taataattct tcgttttctt ttaaaagctt gattttatca
    15421 ggatcttcca aagtatatcc agcttctgtc aagatcgttc gagcagctag atcatttgtt
    15481 gtagagataa cgatgaaatc ttgcgctgtt tggttcaatt cagccattgt acattgtttg
    15541 atgatctttc cttgattgat caggatcagc tcatcgacca ttttttcaag ctcgctgagt
    15601 aagtgactgg agatcaagaa agaggtgccc tgagtagcca agtcggtaat gatttttcgc
    15661 acatctcttg ttgcttgtgg atccaaaccg ttcatcggct catctaaaat aacgatagac
    15721 ggatggttca gtaaggcaag agcaattccc aatttttgtt tcattcccaa cgagtaggat
    15781 ttcgcttttt tgtgaatgta cttttccatc ttgagctgat tcacgatagt gtcgatagca
    15841 gatacatcgt tggtttcaga gaataacttc agatgatcat agcctgttaa gaatggatag
    15901 atacccgggt attcgatcaa tgctcctact tgttccaacc ctttatgact agagggagaa
    15961 atctcatttt caccaataca gattgttcca tctgagtaat ggatcagtcc taaaatagct
    16021 ttcatgatcg ttgtttttcc agcgccatta ggacctacta atccaacgat tttgccaggg
    16081 gataagctaa aactgacatc gctgagggct tgtttgtgac caaagttctt ggataattct
    16141 tggaccgaaa gacttttcaa aaatattcac tccttttcta tagatagtac aagcatacac
    16201 ctgatgagtg gagaagtcgc taggtcattg gacttatttc ttattttttc ataaaaaaat
    16261 tgaatattaa ataaaaaggc ttattttttc tgatcagtac ttattccaag tgtctagtgg
    16321 ccgctagtaa tcttgatgcc aatgatactg atgagtagca tccccacaaa gaaccaagtg
    16381 gaaagattca gcttatcatg aaacaagacc acaccaatta tgaccgaacc aactgcgcca
    16441 atccctgtcc agataggata agagagactc atcggcaaac ttttgattgc ctttgacaaa
    16501 aagtaaaaac tagcaatcat gccaatcact gtgtaaaaag aataattgat tttagaaaaa
    16561 ccatcactcc atttcatcat cgttgaccag aatacttcca aaattcctgc tatgattaat
    16621 tccatccatg ccatacttac attcctcctt aactataaaa aaatacacaa aaagaggaaa
    16681 atcatccctt aaaagaccta atggaatgat catcctcttt atcctacccg gtggcagatc
    16741 gtatatcttt ttctgtagta tagcacacct atccagatat cggcaatctc atacttttta
    16801 gtaaagtgta ccaagcactg acggatatat cgttagcgga aaagaagatg aatgctttgc
    16861 aatttcatag aaagaagttg ttatttatta atcatttaaa aaaaacagta actagacctt
    16921 atttctatat attatcgggc aataaattaa aaaaagcttt accttacaat aagtaagata
    16981 atttttgtga taaaaaaata acgaaaaata tttaaaaata gtgtctattt cgtgagaaaa
    17041 caactatatt ttttatgtgt tttgctttat aattaaaaaa atattgtcat tttatggagg
    17101 aaaatatatg gaaaattatc ttagcctttt aggcgtcttg attgttattc tcgggtttgc
    17161 atttaaatta gactcgatat tgatcgtaat ggttgcttta gttgttacag ctttgactgg
    17221 cggtcttggc attcaaggaa tgttagaact tttaggtaca agttttgtaa acaa
//
LOCUS       DAPBBR010000192        10858 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.077, whole genome shotgun sequence.
ACCESSION   DAPBBR010000192 DAPBBR010000000
VERSION     DAPBBR010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.077"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            40..639
                     /locus_tag="RD488_002913"
                     /pseudo
     CDS             40..639
                     /locus_tag="RD488_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
     gene            792..1277
                     /gene="vanZ"
                     /locus_tag="RD488_002914"
     CDS             792..1277
                     /gene="vanZ"
                     /locus_tag="RD488_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HDT7658891.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(1564..1893)
                     /locus_tag="RD488_002915"
     CDS             complement(1564..1893)
                     /locus_tag="RD488_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658892.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            2198..2527
                     /locus_tag="RD488_002916"
     CDS             2198..2527
                     /locus_tag="RD488_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7658893.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2517..2804
                     /locus_tag="RD488_002917"
     CDS             2517..2804
                     /locus_tag="RD488_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7658894.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(3083..3646)
                     /locus_tag="RD488_002918"
     CDS             complement(3083..3646)
                     /locus_tag="RD488_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658895.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(3839..4411)
                     /locus_tag="RD488_002919"
     CDS             complement(3839..4411)
                     /locus_tag="RD488_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HDT7658896.1"
                     /translation="MNKAIFWDLLGTLGGDSRTLINQNFNFFKDTIPALKKAAQSHYL
                     NIIITNQSHISHGRITMAEYTDALESLINELEKNDIQITDVYTCPHARKDNCDCKKPQ
                     PTFVNEALKKYDLNPSKCFVVGDSGKNDMMLAKNAGINSVLLLTGEGIDSLTKYRHLW
                     SETKPTFIAENSLDAINKIHMYADGDSSDS"
     gene            5199..5774
                     /locus_tag="RD488_002920"
     CDS             5199..5774
                     /locus_tag="RD488_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658897.1"
                     /translation="MKNKFKYLFTILALLPITTSTLITPTIAKASEKQEDSVSYEIVK
                     NDLYIQFEEELAELIASNQSTVSVPDLFSTQSVLSTSSQDNSISEEQFFSLVEKYDGA
                     ELTAVVNSQDAFTTKFVNGGVNSYATSYRGLNALRSELKYNAGALKVGGTLVGTAGGL
                     LGVLLGMVTGDYLSGHCDDAAAGVSAFIQAG"
     gene            complement(5957..6709)
                     /gene="istB"
                     /locus_tag="RD488_002921"
     CDS             complement(5957..6709)
                     /gene="istB"
                     /locus_tag="RD488_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HDT7658898.1"
                     /translation="MMLNEQTEVKLAELKLSGMLESYREQMTNKEYQSMSFEDRFNLM
                     VDLEHSRRKNNKLQRLIKSANFRNASASIEDIEYHPDRNLDKNLILKLASGTYLEEHH
                     NIILMGASGNGKTYIANAFGIQACRQYYNVKYIRLPELLDELTISKNQADGSFRKIIN
                     RYKKVQLLIIDEWLLTNLSLENSTFLLEIIESRLKTASTIFCSQFHPEGWHEKLGNPQ
                     IADAILDRIIHDSYQILVDGKVSMRERYGIRN"
     gene            complement(6709..8250)
                     /gene="istA"
                     /locus_tag="RD488_002922"
     CDS             complement(6709..8250)
                     /gene="istA"
                     /locus_tag="RD488_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDT7658899.1"
                     /translation="MFRYRRILEMHSEGISIRSIAASTGNSRQKITEVIRKAEEKGIA
                     RALSEEMTDQWLGEFLFPEKQLEANGRHLPDFDKIHKELAKPNVTLTLLHQEYAVECR
                     MSGKIPYAYRTFCDYYNAFARKHKATMRIRRKPGEIMEVDWAGSPAYVIDRDTGEKVK
                     AYVFVATLPCSQLSYAEAFLTMKSVAWITAHNHAFEYFGGSTDIIVPDNLKTGVKKNE
                     GIDVILNESYRELGEHYGSIILPARVSTPKDKPSVEGSVGVISTWIIAALRNTHCFTI
                     EDLNREIRMKLNEFNERPFTKKPGSRIRAFEEEEKFALNPLPLAPYKMSVWKKAKVQL
                     NYHVSVESMFYSVPYEYIQQNIDIRMTENLIELYFNSMRIATHKRLYGKFGQYSTVRD
                     HMPDNHKMYVDHTPESSMEWAETIGSSTVKVVQHLLDRYQNEKQALKSIMSLKSFGKK
                     YSKNEIETACSTALNLASLPSVKIIQTILKGNKQKRATSQSHIEDTNIEKHGFTRGAS
                     YFGGK"
     gene            9164..9628
                     /locus_tag="RD488_002923"
     CDS             9164..9628
                     /locus_tag="RD488_002923"
                     /inference="COORDINATES: protein motif:HMM:NF037267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5626 family protein"
                     /protein_id="HDT7658900.1"
                     /translation="MRQVLLVVTLCLSFFLFEVNTVEAYVANNGVYYNLIQGGTQEFM
                     EVDEEGNPILIRVEEVPGLSLFSVNNGNYKISGSKFGMWKANYYVTVSNNQFIRAYSP
                     SAVAVTGSFTSTRLSLVSSKKASYTLEWKAGILSSNSYLDATLTDNSINITY"
     gene            complement(9625..10149)
                     /locus_tag="RD488_002924"
     CDS             complement(9625..10149)
                     /locus_tag="RD488_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7658901.1"
                     /translation="MQNDIRGKIKKSRHIKGISQSEVAKYLNISRQSISKWENDTSSP
                     DINNLTLLSSLYEISIDDLLKEKKEVKKNIKENSIEIIESKNKLIYLKNNTNRDEGLV
                     LLLISLIGCLISPLGLIIAPVVLKRNKATNTFYKGVIAASVICFTVSLFVSYGHFSNI
                     FHWGGSTNVEYIEN"
     gene            complement(10199..>10858)
                     /locus_tag="RD488_002925"
     CDS             complement(10199..>10858)
                     /locus_tag="RD488_002925"
                     /inference="COORDINATES: protein motif:HMM:NF015755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7658902.1"
                     /translation="LFDSRFKTLQQNRYVDIIGYDTYDKINHAYAFGGVAMTINTIQA
                     YLDIPIDFFVTLNMQGLEQIVDSIGGITLTPTATFTQDSYSFYQGEIINLDGKASLAY
                     SRNRHADDSGDYGRQARQREIIMAIIEKGTKVTTLATKIPSLIKSLQGNMTTNLSVDD
                     MWTIINKYSTALGNIEQVQLKGEGQLLDDGIYYEMINEESLEEVQNILQKQLDYHLNI
                     D"
BASE COUNT         3440 a         1820 c         1894 g         3704 t
ORIGIN      
        1 tattctttag gatattaaaa ttaactagca ccacgggtta atatttatat gtcaaaagaa
       61 atagcacaaa aattttcaga gatggtcaat gatgctgtaa agggtggcgt tagtcatttt
      121 attattaata gtggctatcg agactttgat gagcaaagtg tgctttacca agaaatgggg
      181 gctgagtatg ccttaccagc aggttatagt gagcataatt caggtttatc actagatgta
      241 ggatcaagct tgacgaaaat ggaacgagcc cctgaaggaa agtggataga agaaaatgct
      301 tggaaatacg ggttcatttt acgttatcca gaggacaaaa cagagttaac aggaattcaa
      361 tatgaaccat ggcatattcg ctatgttggt ttaccacata gtgcgattat gaaagaaaag
      421 aatttcgttc tcgaggaata tatggattac ctaaaagaag aaaaaaccat ttctgttagt
      481 gtaaatgggg aaaaatatga gatcttttat tatcctgtta ctaaaaatac caccattcat
      541 gtgccgacta atcttcgtta tgagatatca ggaaacaata tagacggtgt aattgtgaca
      601 gtgtttcccg gatcaacaca tactaattca aggaggtaag gatggcggaa tgaaaccaac
      661 gaaattaatg aacagcatta ttgtactagc acttttgggg taacgttagc tttttaattt
      721 aaaacccacg ttaactagga cattgctata ctaatgatac aacttaaaca aaagaattag
      781 aggaaattat attgggaaaa atattatcta gaggattgct agctttatat ttagtgacac
      841 taatctggtt agtgttattc aaattacaat acaatatttt atcagtattt aattatcatc
      901 aaagaagtct taacttgact ccatttactg ctactgggaa tttcagagag atgatagata
      961 atgttataat ctttattcca tttggcttgc ttttgaatgt caattttaaa gaaatcggat
     1021 ttttacctaa gtttgctttt gtactggttt taagtcttac ttttgaaata attcaattta
     1081 tcttcgctat tggagcgaca gacataacag atgtaattac aaatactgtt ggaggctttc
     1141 ttggactgaa attatatggt ttaagcaata agcatatgaa tcaaaaaaaa ttagacagag
     1201 ttattatttt tgtaggtata cttttgctcg tattattgct cgtttaccgt acccatttaa
     1261 gaataaatta cgtgtaagat gtctaaatca agcaatctga tctttcatac acataaagat
     1321 attgaatgaa ttggattaga tggaaaacgg gatgtgggga aactcgcccg taggtgtgaa
     1381 gtgaggggaa aaccggtgat aaagtaaaaa gcttacctaa cactatagta acaaagaaag
     1441 cccaattatc aattttagtg ctgaggaatt ggtctcttta ataaatttcc ttaacgttgt
     1501 aaatccgcat tttcctgacg gtacccccaa actaagattt catagataga ttttctgata
     1561 actttaaaaa acacgaatag cggaaaggat gtcttcattc gctaaagagt aataaactac
     1621 ttttccatct tgacgtgatt ttgccattcc atgttttttt aaaaaacgta aatggtgtga
     1681 cgttgtagcg acactagcag taagtatttc tgctaaatca cagacgcaca tttccttata
     1741 ggtttctaaa gcatagaaaa ttttaattct agaaaaatcg ctgaaacatt tccctaacac
     1801 aagtaagttt gaaaaatctt tttgatccaa tttatttttt attccattta ctttttcttt
     1861 atgtacgaca gtcacttggc aaactttttt cattcatctc acctcacatt caaacgatta
     1921 tttgaatgaa gtatacctat ttgatcactc ttttgtcaat ctaccttaat tccaatacac
     1981 tattataagc aatttcatgt attgaagtaa acttacttgc aagtgcgttt ttgattccaa
     2041 gttaaaaaca tattattatt ctacataatt tcctaatcaa ataaaactcc tttgaaaatt
     2101 gttctaaagg agttttatta ttttgtattt ctactaaaaa tagcgtacaa tgtaattact
     2161 aagtaattac gaaatgtaaa ataatggagg aaataatatg attacaaaaa caagaaaaca
     2221 aggaaattct attatgttaa cggtccctaa agaattcgat gtgcccaatg gtgttgaagt
     2281 agaagctaag cttgtagaga atggtatcct ttatgagttt gtagagccta aaaaagaatt
     2341 ttttgatttt agtgaagata ttttggctga tattctttca gaaggttata gcaaacaaga
     2401 gatcttaaaa gaatttagaa atagaaaaaa tgcgttaact tctgcattta aatctattgc
     2461 tgaagatact gttgcaaatt ctaaaccgat gacaaaagag gagttggcag cagaaattgg
     2521 cttatgagat tctaccttct aaacacgtaa taaagtatct aaaaaaatta aaagagaaaa
     2581 cattaaaaga acaattttta acgataattt atgatgagat agcagttcgt cctcattcgg
     2641 gagaacaaaa aacgggtgat ttatcaggaa tttgggctat tggattcaag tatgcaggta
     2701 cgacatatcg cgttgcatat gaaattaaag ataatgcagt gatacctatc ttactatgtg
     2761 gaacgcatga aaatttttat gaacaattaa aaaagattag gtaagaaccc aatgtttcaa
     2821 cttgagagga tagacgacac tttaaaagat aatttttaac agctgagagt tgtaataccc
     2881 tataatttta aaccactaac ctatatattt atgaaaaata gaaaaaatta aaacgcattt
     2941 taagcctctt tcaaattaaa agcttcatcc ttatgcacaa agagggctta aaatgcgtta
     3001 ttttatattg ttttttagta ataataaaaa aatcactcta attctcccat aaatattata
     3061 gattcctaaa gattaaaata gattattccc tattgtcttt taagtagcgg tagagtgttg
     3121 ccttgctaat accagtcatt tccgtaattt cttttacgct ataaacctga cttttataca
     3181 attttactgc tcgatcaaca tctttctggt tcactcgtgg acggccacct ttacgacctc
     3241 tcgcacgtgc acttttcaaa ccttctttgg tacgttcaac aattaaatca cgttcgaact
     3301 gactaaatgc ttggaagaca gtcatcatta agcgtccgtg aggcgtgctg gtatcgaagt
     3361 tttctttcaa gctcaccagc ttaacatggt gttcttcaaa ataggtaaca aggtcaatca
     3421 aatcctttgt actacgaccc aatcgagaaa aactttctac aattaccgta tctcccggac
     3481 gaattttatc ttttaaacga tttagttggg gacgaaccgc tttggttccc gtcattttct
     3541 cagttaggat ttcattacaa ttttgttcat tgagtaagtc taattgacga tttagttctt
     3601 gtgaacgtgt actcactcgg gcataaccat aaatgtatcc actcatgctt ttcttccttt
     3661 cgtactttaa ttctggcttg attgtatcat aaaagggagt tatagataca tagttaatgc
     3721 aacaagttat gatacaaaat atgacctctt ttatttaata aaagaggtca tttcattttg
     3781 tctcataatc gattgttttt gatacggttt ttagtaataa atggagactc ttctggtatc
     3841 atgaatcaga agagtctcca tctgcataca tatgtatttt atttatagca tctaaactgt
     3901 tttcagcaat aaaagtaggt tttgtttcac tccacagatg tctatatttg gttaaactat
     3961 caattccctc tcccgttaaa agtaaaacac tgtttatacc agcatttttg gccaacatca
     4021 tatcgttttt accggaatcg cctactacga aacacttact tggatttaaa tcgtattttt
     4081 ttaatgcttc attgacaaat gtaggttgag gcttcttgca atcacaattg tcttttctag
     4141 catgagggca agtgtataca tccgttattt gaatgtcatt tttctctaac tcatttatta
     4201 agctctctaa ggcatcagta tattctgcca tagtaatacg tccatgtgaa atatgacttt
     4261 gattcgtaat gatgatattt agataatgac tttgtgccgc tttttttaag gccggtattg
     4321 tgtctttaaa aaaattgaaa ttttgattaa tcagtgttct actatcccct cccagcgtac
     4381 ctaacagatc ccaaaatata gctttattca tggatatttg tctccctctc attttaagaa
     4441 tagttaacta acaagccaag gtgcttacag tatttaaaag tagttcttcg taattaaaac
     4501 aaaaatatta ctttttgaaa aagcatattt tattttgcca gtttaactat atcatattta
     4561 caggagccac tctctattca ctttctatat gaacttcttt tgagggaatg gatatttcga
     4621 atcacataat cactgatata gaagagactt agaatttcag ttatattttg atacagcaaa
     4681 gagtgtaaaa aagaagatac cctcgttggc gaaaaacatt tgaatacaaa ccttactttt
     4741 ttgatgggat ttccatgcta ggagcacata aaaaactaag gtgataataa atttatagtg
     4801 atttagtgtg gaggttcttt tgttaattga aaccataaat agtaaaaaaa tctattttta
     4861 atgattgtac atattaaaga gaaaattgat atacaccagc ttatcaaagt tgagattaat
     4921 actactactt tgacctatga agatgatttt ataaatacct tatagtaaag aaaagttcaa
     4981 ttttttctgc tatcatcttt ttttataaaa gcaacgatta gtttcccaga tgtaaataga
     5041 aaagtgcttt tgaaacagct cgaaaaacat aataatagat tgtgagagga ggaaaaacta
     5101 ttgcaaaatc attacgtaag agatgttact cttgcttaga ttttttattt ttcaagttgt
     5161 ggtattaaaa gtagaaaaaa tagaaagaag gataaaaaat gaaaaataaa tttaagtatt
     5221 tatttactat tttagcctta ttgccaatta ctacatcgac cttaattact cctacaatag
     5281 ccaaagcttc tgaaaaacag gaagattctg ttagttatga aattgtaaaa aatgatcttt
     5341 acattcagtt tgaagaagag ttagctgaat tgattgcttc caatcaatca actgtttcag
     5401 tccctgattt attttctaca caatcagtat tatctacttc tagtcaagat aattctatta
     5461 gtgaagagca atttttttct ttagtcgaaa aatatgatgg agctgaattg acagctgttg
     5521 ttaattcaca agatgctttc acaactaaat ttgtgaatgg tggggttaac tcatatgcta
     5581 cttcttacag aggattaaat gcattgcgta gcgagttgaa gtataatgct ggtgctttga
     5641 aagtaggagg taccttagtt ggcacagctg ggggattgtt aggagtatta ttaggcatgg
     5701 ttacagggga ttatttatct ggccattgcg atgatgcagc agcaggtgtt agtgccttta
     5761 ttcaagctgg ttgaatacgg catcgaaaat gtaccactag agcattgttt tttaccacta
     5821 agtgcaaaga aatgtaccag taagtgcgac gcggttacca tttcaaataa taaaagcgac
     5881 aataatgacc acaaggtcaa ctaagagcca ctcatgaaaa tcatggagtg gctcttaatt
     5941 tattttaatg actcatttaa ttacggatgc cgtaacgttc acgcatagaa actttaccgt
     6001 ctaccagaat ttgataagaa tcatgtatga tcctatctag aatggcatca gcgatttggg
     6061 ggttgccgag cttttcgtgc catccttctg gatggaattg agaacagaaa atagttgatg
     6121 ctgttttaag acgggattcg attatttcca atagaaaggt ggaattttct aacgaaagat
     6181 tggttaatag ccattcatcg atgatgagta attgaacttt tttatatctg ttgattattt
     6241 ttcgaaaact accatctgct tgatttttcg agatggttaa ttcatctagt agttcaggga
     6301 gtcggatgta tttcacgttg tagtattgcc ggcatgcctg tattccgaag gcattggcga
     6361 tatacgtttt cccattccct gaagcgccca tcaaaatgat gttatggtgt tcttccaaat
     6421 aagtcccact ggctagtttt aaaatgaggt tcttatctaa attacggtcc ggatggtatt
     6481 cgatatcctc aatgctggca gaggcatttc taaagtttgc agatttaatc aaccgctgta
     6541 gtttattatt ttttcgccgg gaatgctcca gatcaaccat gaggttgaag cggtcttcga
     6601 aactcatgga ttggtactct ttatttgtca tctgttcacg ataggattca agcatgcctg
     6661 aaagtttcaa ttcagctaat tttacttctg tttgctcatt taacatcatt atttccctcc
     6721 aaaataggac gcaccgcgag tgaatccatg cttttcaatg ttagtgtctt caatatgtga
     6781 ttggcttgtt gctcgcttct gcttgttgcc ctttagaatg gtctggataa ttttaacaga
     6841 aggcaaagaa gccagattta aagctgttga acaggccgtt tctatttcat ttttagaata
     6901 ctttttacca aagctcttca aagacatgat cgactttaag gcttgttttt cattttgata
     6961 acggtctaag aggtgttgaa caacctttac tgttgaggaa ccgatggttt cagcccattc
     7021 catcgaggat tctggggtat ggtccacata cattttgtga ttatctggca tatgatctct
     7081 gacagtcgaa tactgcccaa atttcccgta cagacgttta tgtgttgcga ttcgcatgga
     7141 attaaaatat agttcaatta gattctctgt cattcgaata tctatatttt gttgaatgta
     7201 ttcgtatgga acggaataaa acatgctttc aactgagacg tggtagttta gttgaacctt
     7261 tgcttttttc cagacagaca tcttataagg tgccagtgga agaggattaa gtgcgaattt
     7321 ttcttcttcc tcgaaggctc tgatcctgga tcctggtttc ttagtgaacg gtcgctcatt
     7381 gaattcattt aatttcattc tgatttcacg atttaaatct tcgattgtaa aacaatgcgt
     7441 attgcgtaag gcagctataa tccaagtgga gatgacgcct acgctgcctt caacactggg
     7501 cttatccttg ggagtagaaa ctcgggcagg taaaatgatg gacccgtaat gttcccctag
     7561 ctctcgatat gattcattaa ggatgacatc gatgccttca ttctttttta cacctgtttt
     7621 tagattatcg ggaacaatta tgtcggtaga accgccaaaa tattcaaatg catggttatg
     7681 tgccgtaatc caagccaccg atttcatcgt taggaatgct tccgcataag acaattggct
     7741 gcacggtaag gttgccacaa agacataagc ctttactttt tcacccgtat ctcgatcgat
     7801 gacataagct ggcgatccag cccaatccac ttccataatt tcaccaggct tccgacggat
     7861 gcgcatagtg gctttatgct ttcgcgcgaa cgcattgtaa tagtcacaaa atgtacgata
     7921 ggcgtaaggg attttcccac tcatgcgaca ctcaactgcg tattcctgat gaagaagcgt
     7981 caaggtcacg tttggtttgg ccaattcctt gtgaatcttg tcgaagtcag gcaggtgccg
     8041 tccattggct tctaattgtt tttctggaaa caaaaattcg cctagccatt gatcggtcat
     8101 ttcttccgac aacgccctcg ctatcccttt ctcctcagct tttcggataa cctcagtaat
     8161 tttctgacgt gagttccccg tgcttgctgc aatactgcga atactaattc cttcactgtg
     8221 catttcaagt atccttcgat aacgaaacat aataaaaata cctcctgtaa aataaatgtc
     8281 acaccctaag gtgtgcacct acattataca agaggtattt gtggtacact gctttgcact
     8341 tactggtaca tttctttgcc gagcctggta aaaattattg cagagatggt acattttcga
     8401 tgccgtaatc actggttaca ctagaggagg atctagggta acccttactg aaggtttccc
     8461 tattagccat attgatagta tttatgaagc tgtaattaat taagcaagaa atgtggagat
     8521 gataaaaagc agttctctct tgggtaaaga gaaaactgct tttatctttt tcgctaatgc
     8581 tttttggaat tacctcgctg tctaaaaagg gaagtcacag aaaaaagaat taacacacta
     8641 cctattatta ttggtagtac agttaaaaga gtaatcttac taagatcaaa atcagaactt
     8701 gctacactat taataacaaa aaacaagcca accaaaaaag taaatacaga tagatattta
     8761 ttagtcataa aagaatcttc ctctcgtatt tttttgttct aggaagctat gctaatctaa
     8821 gttcttccta agtatagtgt ctcatctaag tatagcttaa ttaagcatct tatggtttac
     8881 atcaggtcac tttatagttg caaccgctca aatttgcttt ttgattttat tatctacgtt
     8941 attagtaaaa aattagttga tttggttttt ttatttcgtt gatattttat ctgtttagta
     9001 agtagagttg gtaacagtga atgtttacta acccagatac acttatatat gcgtccattt
     9061 gtagagagag ccgtttcaat ataagaatgt tcacaaaatg ttctcttact aattaaaccc
     9121 gtatatatta aactatgagt atattaattt taggagggat tttttgagac aagttttatt
     9181 ggttgttact ttatgtttat ctttcttttt atttgaagta aacactgtag aagcatatgt
     9241 ggcaaataat ggagtctact ataacttaat ccaaggtggc acgcaagagt tcatggaggt
     9301 agacgaagaa ggaaatccta tcttgattcg tgtggaagag gttcccgggc tctccctgtt
     9361 ctccgtcaac aacggaaatt ataaaatatc tggatctaaa tttggaatgt ggaaggcaaa
     9421 ttactatgtg acagtctcga ataaccaatt tattagggcc tactcccctt ctgcagtcgc
     9481 agtgaccgga tcctttacta gcacgagact gtctctcgtc tccagcaaaa aagctagcta
     9541 cacattagaa tggaaagctg gaattttatc tagtaactct tatctagatg ctacactgac
     9601 agataattcc attaatatta cgtattagtt ctcaatatat tccacgttag tggagccgcc
     9661 ccaatgaaag atattactaa aatgtccata ggagacaaac aggcttactg taaaacagat
     9721 gactgaagca gcaatcactc ctttataaaa agtgtttgtt gctttatttc ttttcagaac
     9781 aacaggcgca ataattagtc caagaggaga aatcaaacag ccgattaagg aaatgagcaa
     9841 taaaactaac ccttcatctc ggtttgtatt attttttaaa taaattaatt tatttttaga
     9901 ttctattatc tctatactat tctcttttat atttttttta acttcttttt tttcttttaa
     9961 aagatcatcg atagagattt catataaact acttaataaa gttaagttgt ttatatctgg
    10021 ggaactagta tcattttccc atttagaaat agattgtcta gatatattta aatattttgc
    10081 tacttcactt tgagagatgc cttttatatg ccgtgatttt ttaatttttc ccctaatgtc
    10141 attctgtatc ctctcctatt aatgactttt atttattgga tattaagaaa tagattattt
    10201 agtctatatt caagtgataa tctagttgtt tttgaaggat attctgaact tcttctaaag
    10261 attcttcgtt aatcatttca tagtatattc cgtcatcaag tagttgtcct tcccccttta
    10321 attgaacttg ctctatattt cctaaagcag tggaatattt attaataata gtccacatat
    10381 cgtcaactga cagattagta gtcatatttc cctgaagact cttaatgagt gaaggtatct
    10441 tagttgctag tgtagtaact ttagttcctt tctctataat tgccattatt atttcccttt
    10501 gacgagcttg tctcccatag tcacctgaat catctgcatg acgatttcga gagtacgcta
    10561 aggaagcctt cccatctaag ttaataattt cgccttgata aaatgaataa ctatcttgtg
    10621 taaaagtggc agttggagta agagttattc ctccaataga atcaacaatt tgttctagac
    10681 cctgcatatt taacgttaca aaaaagtcaa taggtatatc taagtatgct tgtattgtat
    10741 ttatagtcat ggctactcca ccaaaggcat aggcatggtt aattttgtcg taagtatcat
    10801 aaccgataat atcgacataa cggttctgtt gcaaagtttt aaatctacta tcaaataa
//
LOCUS       DAPBBR010000193         8062 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.095, whole genome shotgun sequence.
ACCESSION   DAPBBR010000193 DAPBBR010000000
VERSION     DAPBBR010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.095"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            128..1564
                     /locus_tag="RD488_002926"
     CDS             128..1564
                     /locus_tag="RD488_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7658903.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="RD488_002927"
     CDS             1753..4200
                     /locus_tag="RD488_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7658904.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="RD488_002928"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="RD488_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7658905.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="RD488_002929"
     CDS             complement(5690..6793)
                     /locus_tag="RD488_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7658906.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD488_002930"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD488_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7658907.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2696 a         1375 c         1751 g         2240 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga aa
//
LOCUS       DAPBBR010000194         5775 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.106, whole genome shotgun sequence.
ACCESSION   DAPBBR010000194 DAPBBR010000000
VERSION     DAPBBR010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.106"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(86..3010)
                     /locus_tag="RD488_002931"
     CDS             complement(86..3010)
                     /locus_tag="RD488_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDT7658908.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3156..3731
                     /locus_tag="RD488_002932"
     CDS             3156..3731
                     /locus_tag="RD488_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7658909.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3945..4640
                     /gene="vanR"
                     /locus_tag="RD488_002933"
     CDS             3945..4640
                     /gene="vanR"
                     /locus_tag="RD488_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7658910.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4618..5769
                     /locus_tag="RD488_002934"
     CDS             4618..5769
                     /locus_tag="RD488_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7658911.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
BASE COUNT         1782 a         1090 c         1090 g         1813 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccgt ctaaaatact ttgttttttt
       61 acctgtctac ttgacagggg gcagttcact ctgagttaaa atggtattct cctagtaaat
      121 taatatgttc ccaacctaag ggcgacatat ggtgtaacaa atcttcatta aagctacctg
      181 tccgtttttt atattcaact gctgttgtta ggtggagagt attccaaata cttatagcat
      241 tgataattat gtttaaagca ctggctcttt gcaattgatg ctgtatggtg cgttctctaa
      301 gctcaccttg ttttccgaag aaaatagctc ttgccaatcc attcatggct tctcctttat
      361 tcaatcctct ttgtattttt cttcttaatg attcatccga tatataattc aaaataaaga
      421 tcgttttttc tattcggccc atctcacgta aggctgtagc taagctgttt tgtcttgaat
      481 aggaacctag cttccccata ataagggatg ctgaaactgt tccctccctt atagaatgag
      541 ctaatcgcaa aacatcctca taattttctt taatgacctt tgtatttatt tgtccacgta
      601 aaatggcttc tagttttgga tactcacttg ctttatctat cgtaaataat tttgagtccg
      661 ataaatccct tattcttggg gcaaatttaa atcctaataa atgagtcagt ccgaatattt
      721 ggtcagtgta accggcagtg tctgtataat gttcctctat gtttagatcc gtctcatgat
      781 gtaacaaacc atccaaaaca tgaatcgcat ctcttgaatt agtatgaata atctttgtgt
      841 agtaagaaga gaattgatca cttgtaaatc ggtagatggt ggctcctttt ccagttccat
      901 aatgtggatt tgcatctgca tgtagtgatg aaacacctag ctgcattctc ataccatctg
      961 acgaagatgt tgtaccgtcg ccccaataga aaggcaattg taatttatga tgaaagttta
     1021 ctaatatggc ttgggcttta ttcatggcat cttcatacat gcgccattga gatacattgg
     1081 ctagttgctt atatgtaagt ccgggtgtgg cttcggccat cttgctcaag ccaatattca
     1141 ttcccattcc taaaagggca gccatgataa tgattgtttc ttccttatct ggttttcgat
     1201 tattggaagc atgagtgaat tgctcatgaa atcctgttat atgggccaca tccatgagta
     1261 aatcagttaa ttttattctt ggtagcatct gataaaggct tgcactaaat ttttttgctt
     1321 cttctggaac atctttttct aagcgtgcaa gtgatagctt tcctttttca agagaaaccc
     1381 catctaactt attggaattg gcagctaacc actttaacct ttcattaaag ctgctggttc
     1441 tctccgttat ataatcttcg aatgataaac taactgataa tctcgtattc cccttcgatt
     1501 gattccatgt atcttccgaa aacaaatatt cctcaaaatc cctatattgt ctgctgccaa
     1561 caatggaaac atctcctgcc cgaacatgct cccgaagttc tgttaaaaca gccatttcat
     1621 agtaatgacg attaattgtt gtaccatcat cctcgtataa atgtcttttc catcgttttg
     1681 aaataaaatc cacaggtgag tcatcaggca cttttcgctt tccagattcg ttcattcctc
     1741 ggataatctc aacagcttgt aaaagtggct catttgcctt tgtagaatga aattccaata
     1801 ctcttaatag cgttggcgta tattttctta gtgaataaaa ccgtttttgc agtaagtcta
     1861 aataatcata gtcggcagga cgtgcaagtt cctgagcctc ttctactgaa gagacaaagg
     1921 tattccattc aataaccgat tctaaaacct taaaaacgtc taatttttcc tctcttgctt
     1981 taattaatgc ttgtccgatg ttcgtaaagt gtataacttt ctcatttagc tttttaccgt
     2041 tttgtttctg gatttcctct tgagccttac gaccttttga taacaaacta agtatttgcc
     2101 tatcatgaat ttcaaacgct ttatccgtta gctcctgagt aagttgtaat aaatagatgg
     2161 ttaatatcga ataacgttta ttttcttgaa agtcacggaa tgcatacggc tcgtatcttg
     2221 agcctaagcg agacagctgc aacaggcggt tacggtgcaa atgactaatt tgcactgttt
     2281 ctaaatccat tcctcgtatg tattcgagtc gttctattat ttttagaaaa gtttcgggtg
     2341 aaggatgacc cggtggctct tttaaccaac ccaatatcgt tttattggat tcggatggat
     2401 gctgcgaggt aataatccct tcaagctttt ctttttgctc atttgttaga gatttactaa
     2461 ccgtattaaa tagcttcttt tcagccattg cccttgcttc ccacaccatt ctttcaagtg
     2521 tagtgatagc aggcagtata attttgtttt ttcttagaaa atctatgcat tcatgcagta
     2581 gatgaatggc atcaccattt tccaaagcta attgatgaag gtacttaaat gtcattcgat
     2641 attcactcag ggtaaaagtt acaaagtcgt attcacttcg aatttctttc aaatgatccc
     2701 aaagtgtatt ttccctttga ggataatgat caagcgagga tggactaaca ccaatctgtt
     2761 tcgatatata ttgtatgacc gaatctggga tgcttttgat atgagtgtat ggccaaccgg
     2821 gataccgaag aacagctaat tgaacagcaa atcctaaacg gttttcttcc ctccttcgct
     2881 tattaactat ttctaaatcc cgtttggaaa aagtgaagta ggtccccagt atccattcat
     2941 cttcagggat ttgcataaaa gcctgtctct gttccggtgt aagcaattct ctacctctcg
     3001 caattttcat tcagtatcat tccatttctg tattttcaat ttattagttc aattatatat
     3061 caatagagtg tactctattg atacaaatgt agtagactga taaaatcata gttaagagcg
     3121 tctcataaga cttgtctcaa aaatgaggtg atattttgcg gaaaatcggt tatattcgtg
     3181 tcagttcgac taaccagaat ccttcaagac aatttcagca gttgaacgag atcggaatgg
     3241 atattatata tgaagagaaa gtttcaggag caacaaagga tcgcgagcaa cttcaaaaag
     3301 tgttagacga tttacaggaa gatgacatca tttatgttac agacttaact cgaatcactc
     3361 gtagtacaca agatctattt gaattaatcg ataacatacg agataaaaag gcaagtttaa
     3421 aatcactaaa agatacatgg cttgatttat cagaagataa tccatacagc caattcttaa
     3481 ttactgtaat ggctggtgtt aaccaattag agcgagatct tattcggatg agacaacgtg
     3541 aagggattga attggctaag aaagaaggaa agtttaaagg tcgattaaag aagtatcata
     3601 aaaatcacgc aggaatgaat tatgcggtaa agctatataa agaaggaaat atgactgtaa
     3661 atcaaatttg tgaaattact aatgtatcta gggcttcatt atacaggaaa ttatcagaag
     3721 tgaataatta gccattctgt attccgctaa tgggcaatat ttttaaagaa gaaaaggaaa
     3781 ctataaaata ttaacagcct cctagcgatg ccgaaaagcc ctttgataaa aaaagaatca
     3841 tcatcttaag aaattcttag tcatttatta tgtaaatgct tataaattcg gccctataat
     3901 ctgataaatt attaagggca aacttatgtg aaagggtgat aactatgagc gataaaatac
     3961 ttattgtgga tgatgaacat gaaattgccg atttggttga attatactta aaaaacgaga
     4021 attatacggt tttcaaatac tataccgcca aagaagcatt ggaatgtata gacaagtctg
     4081 agattgacct tgccatattg gacatcatgc ttcccggcac aagcggcctt actatctgtc
     4141 aaaaaataag ggacaagcac acctatccga ttatcatgct gaccgggaaa gatacagagg
     4201 tagataaaat tacagggtta acaatcggcg cggatgatta tataacgaag ccctttcgcc
     4261 cactggagtt aattgctcgg gtaaaggccc agttgcgccg atacaaaaaa ttcagtggag
     4321 taaaggagca gaacgaaaat gttatcgtcc actccggcct tgtcattaat gttaacaccc
     4381 atgagtgtta tctgaacgag aagcagttat cccttactcc caccgagttt tcaatactgc
     4441 gaatcctctg tgaaaacaag gggaatgtgg ttagctccga gctgctattt catgagatat
     4501 ggggcgacga atatttcagc aagagcaaca acaccatcac cgtgcatatc cggcatttgc
     4561 gcgaaaaaat gaacgacacc attgataatc cgaaatatat aaaaacggta tggggggttg
     4621 gttataaaat tgaaaaataa aaaaaacgac tattccaaac tagaacgaaa actttacatg
     4681 tatatcgttg caattgttgt ggtagcaatt gtattcgtgt tgtatattcg ttcaatgatc
     4741 cgagggaaac ttggggattg gatcttaagt attttggaaa acaaatatga cttaaatcac
     4801 ctggacgcga tgaaattata tcaatattcc atacggaaca atatagatat ctttatttat
     4861 gtggcgattg tcattagtat tcttattcta tgtcgcgtca tgctttcaaa attcgcaaaa
     4921 tactttgacg agataaatac cggcattgat gtacttattc agaacgaaga taaacaaatt
     4981 gagctttctg cggaaatgga tgttatggaa caaaagctca acacattaaa acggactctg
     5041 gaaaagcgag agcaggatgc aaagctggcc gaacaaagaa aaaatgacgt tgttatgtac
     5101 ttggcgcacg atattaaaac gccccttaca tccattatcg gttatttgag cctgcttgac
     5161 gaggctccag acatgccggt agatcaaaag gcaaagtatg tgcatatcac gttggacaaa
     5221 gcgtatcgac tcgaacagct aatcgacgag ttttttgaga ttacacggta taacctacaa
     5281 acgataacgc taacaaaaac gcacatagac ctatactata tgctggtgca gatgaccgat
     5341 gaattttatc ctcagctttc cgcacatgga aaacaggcgg ttattcacgc ccccgaggat
     5401 ctgaccgtgt ccggcgaccc tgataaactc gcgagagtct ttaacaacat tttgaaaaac
     5461 gccgctgcat acagtgagga taacagcatc attgacatta ccgcgggcct ctccggggat
     5521 gtggtgtcaa tcgaattcaa gaacactgga agcatcccaa aagataagct agctgccata
     5581 tttgaaaagt tctataggct ggacaatgct cgttcttccg atacgggtgg cgcgggactt
     5641 ggattggcga ttgcaaaaga aattattgtt cagcatggag ggcagattta cgcggaaagc
     5701 aatgataact atacgacgtt tagggtagag cttccagggt tctgttgcaa agttttaaat
     5761 aaagaataaa atccc
//
LOCUS       DAPBBR010000195         3970 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.118, whole genome shotgun sequence.
ACCESSION   DAPBBR010000195 DAPBBR010000000
VERSION     DAPBBR010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.118"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="RD488_002935"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="RD488_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDT7658912.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD488_002936"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD488_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7658913.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1254 a          613 c          818 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DAPBBR010000196         3970 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.119, whole genome shotgun sequence.
ACCESSION   DAPBBR010000196 DAPBBR010000000
VERSION     DAPBBR010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.119"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="RD488_002937"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="RD488_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDT7658914.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD488_002938"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="RD488_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7658915.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1253 a          613 c          819 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DAPBBR010000197         2948 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.128, whole genome shotgun sequence.
ACCESSION   DAPBBR010000197 DAPBBR010000000
VERSION     DAPBBR010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.128"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            295..1263
                     /locus_tag="RD488_002939"
     CDS             295..1263
                     /locus_tag="RD488_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7658916.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1256..2287
                     /gene="vanA"
                     /locus_tag="RD488_002940"
     CDS             1256..2287
                     /gene="vanA"
                     /locus_tag="RD488_002940"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7658917.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2293..2901
                     /locus_tag="RD488_002941"
     CDS             2293..2901
                     /locus_tag="RD488_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7658918.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          876 a          561 c          714 g          797 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccgct tccagcgatg ccagacttgg
       61 ttgataaaag gaggtcctaa gagatgtata taatttttta ggaaaatctc aaggttatct
      121 ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc ttacacggta
      181 gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg acaagattac
      241 cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt aattatgaat
      301 aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt ccatgctctt
      361 tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga atccaacgcc
      421 aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat ttccgcctct
      481 attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag catcggctgc
      541 aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa tgtggcgtac
      601 tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt acgcaacgta
      661 aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga ccgtggcaag
      721 gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa agcggttatt
      781 gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg aagtatagag
      841 gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac gcttcatgtg
      901 ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag aatgaagcaa
      961 ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga gttggttaaa
     1021 gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg agaggaagag
     1081 tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact taaacttcaa
     1141 agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca agcgttgcgt
     1201 gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca ggagcatgaa
     1261 tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg tatcggtaaa
     1321 atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt tatacattgg
     1381 aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat gggaaaacga
     1441 caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac ttgttaaaaa
     1501 gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc atggcaagtc
     1561 aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt ttgtaggctg
     1621 cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg ttgcgaaaaa
     1681 tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc cggtggcagc
     1741 tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct tcggtgtgaa
     1801 aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac aatatgacag
     1861 caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg tattgggaaa
     1921 cagtgccgcg ttagttgttg gcgaggtgga ccaaatcagg ctgcagtacg gaatctttcg
     1981 tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa ccgttcccgc
     2041 agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa tatataaagc
     2101 gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg gccgcattgt
     2161 actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc cccgtatgat
     2221 ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat tagcgttaaa
     2281 ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca cggtgttcgt
     2341 tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga cggttatgaa
     2401 gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc aaaagaactg
     2461 gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa gcgtgctgta
     2521 aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga aagttattat
     2581 cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa atcaagccat
     2641 agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga gcttgtacca
     2701 atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa tggaatatca
     2761 tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag tgggtttgaa
     2821 gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc caatagctat
     2881 tttgatttcc ccgttaaata aacttttaac ggttctgttg caaagtttta aataaagaat
     2941 aaaatccc
//
LOCUS       DAPBBR010000198         2565 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.134, whole genome shotgun sequence.
ACCESSION   DAPBBR010000198 DAPBBR010000000
VERSION     DAPBBR010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.134"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(39..341)
                     /locus_tag="RD488_002942"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="RD488_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1055..1345)
                     /locus_tag="RD488_002943"
     CDS             complement(1055..1345)
                     /locus_tag="RD488_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7658919.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2244)
                     /locus_tag="RD488_002944"
                     /pseudo
     CDS             complement(1553..2244)
                     /locus_tag="RD488_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          759 a          472 c          356 g          978 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgatttc tacatttgtt ttttcttgtg tcagtgttgc
     1741 gatttgttga ttcaaaccat ttacagtatt ttgtaattct gaaagttttg cttgtgcttc
     1801 ttgtagtctt gctgtccaat ctgcattcag atgattgatt tcatcatttt tttggttgat
     1861 ctcatctagt ttgacattga tttcattttg tttgctttgt agttgtgcat ccttgctgac
     1921 taattgactt tctaagtttt gtttttctgc tgccgattga tttttttggt tttctaattc
     1981 atttactttt gtttggtatt cttggacatc tgcctttgaa tcttgcaatg tctgttcttt
     2041 ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct ttatctgtca atgtatgatc
     2101 aagctgtgtc agattctcat tgattgtatc aatatctgtc tctccacccc acaaaataat
     2161 ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat agaaatgcaa cgacaatccc
     2221 accagtaata aatttctttt tcatttgcat agctccttaa tccaatactt ttacatgcta
     2281 aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa ttacatatgt aattttaata
     2341 taaatactat caaatactca tttaatcctc cttttttatc tatttaaaaa atctttttta
     2401 tagagaaaaa tgcaggttaa tactttctta aataaatatt tatggtgaac aaaaacaaaa
     2461 aagcaagttt tattaaacgt aacccttttc atttcataga ttactgtatt tattacaaaa
     2521 aacgcggatt tgtcataaat tgtcatgctt cttttaccta tgaaa
//
LOCUS       DAPBBR010000199         1998 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.141, whole genome shotgun sequence.
ACCESSION   DAPBBR010000199 DAPBBR010000000
VERSION     DAPBBR010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.141"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            47..439
                     /locus_tag="RD488_002945"
     CDS             47..439
                     /locus_tag="RD488_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7658920.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            440..1879
                     /locus_tag="RD488_002946"
                     /note="aph(2'')-Ia"
     CDS             440..1879
                     /locus_tag="RD488_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDT7658921.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          831 a          153 c          343 g          671 t
ORIGIN      
        1 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
       61 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      121 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      181 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      241 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      301 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      361 atatgaaaaa ttaggtggta aaaatgatta taaagatgaa atagtatatg tatatgatta
      421 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      481 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      541 tggtggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      601 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
      661 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
      721 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
      781 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
      841 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
      901 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
      961 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1021 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1081 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     1141 aaaaggttat gcaaaagaaa aagcaatata taatttttta aatacaaatt tagaaactaa
     1201 tgtaaaaatt cctaatattg aatattcgta tattagtgat gaattatcta tactaggtta
     1261 taaagaaatt aaaggaactt ttttaacacc agaaatttat tctactatgt cagaagaaga
     1321 acaaaatttg ttaaaacgag atattgccag ttttttaaga caaatgcacg gtttagatta
     1381 tacagatatt agtgaatgta ctattgataa taaacaaaat gtattagaag agtatatatt
     1441 gttgcgtgaa actatttata atgatttaac tgatatagaa aaagattata tagaaagttt
     1501 tatggaaaga ctaaatgcaa caacagtttt tgagggtaaa aagtgtttat gccataatga
     1561 ttttagttgt aatcatctat tgttagatgg caataataga ttaactggaa taattgattt
     1621 tggagattct ggaattatag atgaatattg tgattttata tacttacttg aagatagtga
     1681 agaagaaata ggaacaaatt ttggagaaga tatattaaga atgtatggaa atatagatat
     1741 tgagaaagca aaagaatatc aagatatagt tgaagaatat tatcctattg aaactattgt
     1801 ttatggaatt aaaaatatta aacaggaatt tatcgaaaat ggtagaaaag aaatttataa
     1861 aaggacttat aaagattgat tatataatat atgaaaagct attataaaag acattagtat
     1921 taaatagttt aaaaaaatga aaaataataa aggaagtgag tcaagtccag actcctgtgt
     1981 aaaatgctat acaatgtt
//
LOCUS       DAPBBR010000200         1031 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-003
            SAMN36683393-rid18908953.guided.168, whole genome shotgun sequence.
ACCESSION   DAPBBR010000200 DAPBBR010000000
VERSION     DAPBBR010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683393
            Sequence Read Archive: SRR25390899
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831668.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831668.1
            Genome Coverage       :: 94x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,878
            Genes (coding)                    :: 2,815
            CDSs (with protein)               :: 2,815
            Genes (RNA)                       :: 70
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 29 of 63
            Pseudo Genes (incomplete)         :: 25 of 63
            Pseudo Genes (internal stop)      :: 15 of 63
            Pseudo Genes (multiple problems)  :: 5 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683393-rid18908953.guided.168"
                     /isolate="VREC-003"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            85..144
                     /gene="ermCL"
                     /locus_tag="RD488_002947"
     CDS             85..144
                     /gene="ermCL"
                     /locus_tag="RD488_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HDT7658922.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            193..927
                     /locus_tag="RD488_002948"
     CDS             193..927
                     /locus_tag="RD488_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HDT7658923.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          415 a          136 c          139 g          341 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccagc ttgtgctata attattctaa
       61 tttcataaaa aggagaatta atatatgggc atttttagta tttttgtaat caacacagtt
      121 cattatcaac caaacaaaaa ataagtggtt ataatggatt gttaatataa aacctcatag
      181 gagtgggtta taatgaacaa aaaaaatata aaagatagtc aaaactttat tacttcaaag
      241 catcatataa atgaaatttt gagaaatgta catttaaata caaatgataa tattattgag
      301 attggttcag ggaaaggtca tttcacgttt gaattagcta aaaggtgtaa ttatgtaacc
      361 gccattgaaa tagatcctaa attatgtagg ataactaaaa acaaacttat tgaatatgag
      421 aacttccagg ttatcaataa agatatttta caatttaagt ttcctaaaaa taagtcatat
      481 aagatatatg gaaatatacc ctacaatata agtacagata taattcgaaa aattgttttt
      541 gaaagcacag ctacagaaag ttatttaata gtggaatatg gatttgctaa aaggttgcta
      601 aatacaaatc gttcactagc actattttta atgacagaag ttgatatatc catattaagt
      661 aaaatcccta gagaatactt tcatccaaaa cctagagtta atagctcgtt aattgtatta
      721 aaaagacacc cttcaaaaat atcactcaaa gatagaaaac aatatgaaaa ttttgttatg
      781 aaatgggtta acaaagaata cataaaacta ttttccaaaa accaatttta tcaagcctta
      841 aaatatgcaa gaattgacga tttaaacaat attagctttg aacaattctt gtctcttttc
      901 aatagctata aattatttaa tagataagtt aaggggtgca taaactgcat cccttaactt
      961 atcttatttt gcttaaacaa tcttggcccg taaactgcat aactcatatg taaatcgctc
     1021 ctttttaggt g
//
